Homo sapiens

105 known processes

PTPN6

protein tyrosine phosphatase, non-receptor type 6

(Aliases: HCP,SHP1,PTP-1C,HPTP1C,HCPH,SHP-1,SH-PTP1,SHP-1L)

PTPN6 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of leukocyte mediated immunityGO:0002703381.000
Mouse
leukocyte activationGO:00453211640.999
Mouse
serotonin transportGO:000683730.999
lymphocyte activationGO:00466491330.998
Mouse
regulation of cellular amine metabolic processGO:0033238110.998
gamma delta t cell activationGO:004662930.997
cellular amino acid metabolic processGO:00065201160.996
osteoclast differentiationGO:0030316210.994
negative regulation of tumor necrosis factor biosynthetic processGO:004253630.992
amine metabolic processGO:0009308440.990
positive regulation of leukocyte activationGO:0002696800.990
cell activationGO:00017752130.990
Mouse
tumor necrosis factor superfamily cytokine productionGO:0071706450.989
organic hydroxy compound transportGO:0015850630.989
regulation of leukocyte activationGO:00026941150.987
Mouse
leukocyte differentiationGO:0002521980.987
Mouse
positive regulation of cell activationGO:0050867810.985
regulation of cytokine biosynthetic processGO:0042035350.985
defense responseGO:00069523150.984
Mouse
negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000282380.984
Mouse
immune response inhibiting cell surface receptor signaling pathwayGO:000276740.984
regulation of mononuclear cell proliferationGO:0032944650.981
Mouse
immune system developmentGO:00025201950.977
Mouse
monoamine transportGO:0015844100.977
adaptive immune responseGO:0002250490.977
Mouse
biological adhesionGO:00226103310.976
Human Mouse
negative regulation of immune system processGO:00026831360.976
Mouse
enzyme linked receptor protein signaling pathwayGO:00071673030.971
Human Fly
regulation of cell differentiationGO:00455953930.970
Mouse Fly
regulation of cell activationGO:00508651250.969
Mouse
b cell activationGO:0042113330.964
Mouse
lymphocyte proliferationGO:0046651700.963
Mouse
immune responseGO:00069553070.962
Mouse
regulation of leukocyte differentiationGO:1902105610.959
Mouse
positive regulation of immunoglobulin mediated immune responseGO:000289140.958
positive regulation of lymphocyte activationGO:0051251730.957
hemopoiesisGO:00300971800.957
Mouse
negative regulation of interleukin 10 productionGO:003269370.954
serotonin secretionGO:000182010.954
hematopoietic or lymphoid organ developmentGO:00485341860.953
Mouse
phosphatidylinositol mediated signalingGO:0048015550.952
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002460400.951
Mouse
interleukin 12 secretionGO:007261010.950
positive regulation of cell proliferationGO:00082843010.948
positive regulation of gamma delta t cell activationGO:004664510.946
regulation of erk1 and erk2 cascadeGO:0070372990.943
leukocyte mediated cytotoxicityGO:0001909270.939
Mouse
regulation of immune responseGO:00507762010.937
Mouse
regulation of regulatory t cell differentiationGO:004558940.936
negative regulation of t cell activation via t cell receptor contact with antigen bound to mhc molecule on antigen presenting cellGO:200118910.933
regulation of myeloid leukocyte mediated immunityGO:000288640.933
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822290.932
Mouse
negative regulation of t cell mediated cytotoxicityGO:000191510.930
negative regulation of transportGO:00510511760.929
regulation of gamma delta t cell activationGO:004664310.926
regulation of tumor necrosis factor biosynthetic processGO:004253480.926
mononuclear cell proliferationGO:0032943710.924
Mouse
cell type specific apoptotic processGO:00972851250.924
negative regulation of peptidyl tyrosine phosphorylationGO:0050732200.922
negative regulation of myeloid cell differentiationGO:0045638420.918
negative regulation of dendritic cell differentiationGO:200119920.917
negative regulation of myeloid leukocyte differentiationGO:0002762160.917
negative regulation of cell differentiationGO:00455961710.916
type i interferon secretionGO:007264110.916
regulation of cellular amino acid metabolic processGO:000652160.915
negative regulation of alpha beta t cell activationGO:004663630.912
regulation of cell migrationGO:00303342890.903
positive regulation of mast cell activationGO:003300520.903
positive regulation of immune responseGO:00507781590.901
Mouse
lipid metabolic processGO:00066293810.898
lymphocyte mediated immunityGO:0002449480.897
Mouse
regulation of gamma delta t cell activation involved in immune responseGO:200119110.885
positive regulation of regulatory t cell differentiationGO:004559130.885
regulation of leukocyte proliferationGO:0070663670.878
Mouse
regulation of cellular ketone metabolic processGO:0010565500.876
regulation of alpha beta t cell activationGO:0046634130.874
immune response regulating signaling pathwayGO:0002764970.873
Mouse
positive regulation of leukocyte differentiationGO:1902107370.871
single organismal cell cell adhesionGO:00163371480.871
Mouse
negative regulation of adaptive immune responseGO:000282090.867
Mouse
negative regulation of leukocyte differentiationGO:1902106240.861
peptidyl tyrosine modificationGO:00182121700.854
positive regulation of cell differentiationGO:00455972110.851
regulation of transforming growth factor beta secretionGO:200120110.849
myeloid cell differentiationGO:00300991170.848
Mouse
defense response to virusGO:0051607710.846
negative regulation of leukocyte apoptotic processGO:2000107160.844
negative regulation of interferon beta productionGO:003268840.843
regulation of lymphocyte proliferationGO:0050670640.839
Mouse
b cell proliferationGO:0042100220.834
regulation of leukocyte apoptotic processGO:2000106250.830
fc receptor mediated inhibitory signaling pathwayGO:000277420.828
leukocyte mediated immunityGO:0002443590.826
Mouse
regulation of production of molecular mediator of immune responseGO:0002700250.824
cytokine biosynthetic processGO:0042089370.821
negative regulation of apoptotic processGO:00430663160.819
Fly
negative regulation of multicellular organismal processGO:00512413170.817
regulation of humoral immune response mediated by circulating immunoglobulinGO:000292330.809
Mouse
regulation of peptidyl tyrosine phosphorylationGO:00507301080.809
phagocytosis recognitionGO:000691030.809
leukocyte migrationGO:00509001070.802
positive regulation of lymphocyte proliferationGO:0050671460.802
negative regulation of protein metabolic processGO:00512483910.800
positive regulation of map kinase activityGO:0043406800.798
positive regulation of cellular amine metabolic processGO:003324070.794
regulation of response to external stimulusGO:00321012220.792
regulation of osteoclast developmentGO:200120410.791
immune response regulating cell surface receptor signaling pathwayGO:0002768510.789
Mouse
regulation of t cell differentiationGO:0045580190.779
erk1 and erk2 cascadeGO:00703711040.778
regulation of interferon beta secretionGO:003554710.770
metal ion homeostasisGO:00550651690.766
Mouse
negative regulation of cell proliferationGO:00082852280.765
Mouse
negative regulation of programmed cell deathGO:00430693210.761
Fly
regulation of myeloid cell differentiationGO:0045637810.761
regulation of protein serine threonine kinase activityGO:00719001790.758
Mouse
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.753
Human Fly
positive regulation of t cell tolerance inductionGO:000266620.749
production of molecular mediator of immune responseGO:0002440370.747
regulation of myeloid leukocyte differentiationGO:0002761390.744
myeloid cell developmentGO:006151550.740
Mouse
t cell differentiationGO:0030217290.731
regulation of interleukin 10 secretionGO:200117940.727
menstrual cycle phaseGO:002260120.721
cellular ketone metabolic processGO:0042180800.719
regulation of blood coagulationGO:0030193420.713
positive regulation of cytolysisGO:004591930.711
positive regulation of dna metabolic processGO:0051054730.710
positive regulation of b cell activationGO:0050871170.706
regulation of anatomical structure morphogenesisGO:00226032860.701
Fly
negative regulation of catalytic activityGO:00430863350.701
Mouse
negative regulation of leukocyte activationGO:0002695260.698
Mouse
immune response inhibiting signal transductionGO:000276540.696
determination of adult lifespanGO:000834020.695
myeloid leukocyte activationGO:0002274340.691
t cell tolerance inductionGO:000251740.690
regulation of dendritic cell apoptotic processGO:200066840.690
myeloid leukocyte differentiationGO:0002573600.682
positive regulation of t cell proliferationGO:0042102330.680
cell killingGO:0001906340.677
Mouse
mast cell activation involved in immune responseGO:000227940.666
negative regulation of cell deathGO:00605483450.662
Fly
regulation of osteoclast differentiationGO:0045670180.656
t cell activationGO:0042110990.653
Mouse
response to biotic stimulusGO:00096072760.649
negative regulation of cell activationGO:0050866330.648
Mouse
positive regulation of lymphocyte differentiationGO:0045621130.644
regulation of b cell proliferationGO:0030888180.644
positive regulation of t cell differentiationGO:0045582110.641
positive regulation of developmental processGO:00510943140.632
regulation of establishment of protein localizationGO:00702012420.626
g protein coupled receptor signaling pathwayGO:00071862070.625
negative regulation of osteoclast developmentGO:200120510.622
negative regulation of t cell mediated immunityGO:000271050.617
memoryGO:000761330.612
t cell mediated immunityGO:0002456250.605
regulation of natural killer cell mediated cytotoxicityGO:0042269160.595
immunoglobulin mediated immune responseGO:0016064100.592
Mouse
regulation of mapk cascadeGO:00434082620.588
regulation of map kinase activityGO:00434051080.586
Mouse
actin cytoskeleton organizationGO:00300362070.576
negative regulation of cytokine biosynthetic processGO:0042036110.575
regulation of ion transportGO:00432691890.568
Mouse
t cell activation via t cell receptor contact with antigen bound to mhc molecule on antigen presenting cellGO:000229140.567
multicellular organismal agingGO:001025930.565
positive regulation of immune system processGO:00026842830.564
Mouse
positive regulation of cellular amino acid metabolic processGO:004576430.559
negative regulation of cellular amine metabolic processGO:003323930.557
regulation of tolerance inductionGO:000264340.555
defense response to other organismGO:00985421290.554
leukocyte apoptotic processGO:0071887310.536
regulation of cell cycleGO:00517263930.527
dendritic cell apoptotic processGO:009704840.525
negative regulation of secretion by cellGO:1903531520.524
lipid biosynthetic processGO:00086101770.522
activation of mapk activityGO:0000187450.514
positive regulation of b cell proliferationGO:0030890120.510
cell activation involved in immune responseGO:0002263300.510
cellular amine metabolic processGO:0044106410.505
negative regulation of leukocyte mediated cytotoxicityGO:000191150.501
positive regulation of immune effector processGO:0002699400.501
negative regulation of immune responseGO:0050777400.500
Mouse
regulation of mast cell activation involved in immune responseGO:003300630.499
negative regulation of lymphocyte proliferationGO:0050672150.498
Mouse
regulation of immunoglobulin mediated immune responseGO:000288970.491
Mouse
metal ion transportGO:00300012720.488
Mouse
positive regulation of jak stat cascadeGO:0046427350.478
positive regulation of programmed cell deathGO:00430682490.469
cation transportGO:00068123310.469
Mouse
glucan metabolic processGO:0044042220.458
anion transportGO:00068201610.456
positive regulation of b cell differentiationGO:004557910.455
positive regulation of alpha beta t cell proliferationGO:004664150.453
regulation of alpha beta t cell differentiationGO:004663750.441
regulation of protein transportGO:00512232130.438
regulation of defense responseGO:00313471540.437
negative regulation of osteoclast differentiationGO:004567180.437
circulatory system developmentGO:00723592620.436
Human
nervous system developmentGO:00073992930.435
Human Fly
t cell receptor signaling pathwayGO:0050852210.432
Mouse
positive regulation of t cell activationGO:0050870540.431
negative regulation of protein modification processGO:00314002000.430
cytokine productionGO:00018162470.428
leukocyte proliferationGO:0070661740.427
Mouse
regulation of stress activated protein kinase signaling cascadeGO:0070302850.419
cellular chemical homeostasisGO:00550821800.415
Mouse
positive regulation of nervous system developmentGO:0051962540.414
negative regulation of dendritic cell apoptotic processGO:200066930.409
negative regulation of phagocytosisGO:005076540.407
interferon beta secretionGO:003554610.407
alpha beta t cell activationGO:0046631150.403
response to lipidGO:00339932060.401
regulation of mast cell degranulationGO:004330430.400
positive regulation of mapk cascadeGO:00434101900.397
negative regulation of cellular component organizationGO:00511292350.395
positive regulation of leukocyte degranulationGO:004330230.392
positive regulation of cell deathGO:00109422630.389
immune effector processGO:00022521590.387
Mouse
lymphocyte differentiationGO:0030098350.384
Mouse
positive regulation of b cell mediated immunityGO:000271440.383
actin filament organizationGO:00070151280.378
positive regulation of peptidyl tyrosine phosphorylationGO:0050731850.370
cellular response to lipidGO:00713961270.369
negative regulation of serotonin secretionGO:001406310.369
regulation of cell developmentGO:00602841610.366
Fly
negative regulation of t cell activationGO:0050868180.353
Mouse
macrophage activation involved in immune responseGO:000228110.351
regulation of synaptic plasticityGO:004816730.349
cell developmentGO:00484683280.346
Mouse Fly
dephosphorylationGO:00163112090.338
response to organonitrogen compoundGO:00102431560.338
Human
negative regulation of developmental processGO:00510932470.337
mast cell degranulationGO:004330340.335
mapk cascadeGO:00001652880.330
lymphocyte activation involved in immune responseGO:0002285200.330
response to cytokineGO:00340972320.329
actin filament based processGO:00300292240.327
regulation of anion transportGO:0044070250.326
regulation of type i interferon productionGO:0032479260.324
negative regulation of cell developmentGO:0010721480.323
cd8 positive alpha beta t cell activationGO:003603730.318
regulation of calcium ion transportGO:0051924790.314
Mouse
positive regulation of cellular catabolic processGO:00313312840.313
cytoplasmic transportGO:00164823790.312
Mouse
regulation of immune effector processGO:0002697910.311
Mouse
regulation of immunoglobulin productionGO:000263740.311
activation of immune responseGO:00022531140.310
Mouse
protein dephosphorylationGO:0006470810.309
cellular response to nitrogen compoundGO:19016991440.307
Human
negative regulation of type 2 immune responseGO:000282930.305
response to other organismGO:00517072610.305
regulation of jak stat cascadeGO:0046425440.305
cytokine production involved in immune responseGO:0002367270.304
negative regulation of ion transportGO:0043271390.302
negative regulation of protein secretionGO:0050709290.296
negative regulation of cellular amino acid metabolic processGO:004576320.295
positive regulation of mononuclear cell proliferationGO:0032946470.295
regulation of ion homeostasisGO:2000021730.289
Mouse
response to estradiolGO:0032355230.289
positive regulation of myeloid leukocyte mediated immunityGO:000288810.289
oogenesisGO:004847720.288
Fly
immune response in mucosal associated lymphoid tissueGO:000238610.286
regulation of dendritic cell differentiationGO:200119830.285
negative regulation of phosphate metabolic processGO:00459362670.285
organic hydroxy compound metabolic processGO:19016151470.284
regulation of lymphocyte activationGO:00512491030.284
Mouse
endothelial cell migrationGO:0043542860.281
positive regulation of leukocyte proliferationGO:0070665480.281
vesicle mediated transportGO:00161923710.275
Fly
tumor necrosis factor biosynthetic processGO:004253380.274
b cell differentiationGO:003018360.273
Mouse
tumor necrosis factor productionGO:0032640430.272
positive regulation of apoptotic processGO:00430652460.272
photoreceptor cell differentiationGO:004653020.270
Fly
calcium ion homeostasisGO:00550741220.269
Mouse
secretionGO:00469032540.257
regulation of defense response to virusGO:0050688330.255
interferon gamma biosynthetic processGO:004209580.255
regulation of platelet aggregationGO:009033040.254
peptidyl tyrosine phosphorylationGO:00181081700.253
cellular calcium ion homeostasisGO:00068741170.253
Mouse
regulation of protein localizationGO:00328802960.253
negative regulation of protein kinase activityGO:0006469980.248
Mouse
negative regulation of mapk cascadeGO:0043409560.248
Mouse
b cell mediated immunityGO:0019724100.244
Mouse
regulation of antigen receptor mediated signaling pathwayGO:0050854100.244
Mouse
carbohydrate transportGO:0008643370.242
Human
gamma delta t cell activation involved in immune responseGO:000229010.241
immune response activating cell surface receptor signaling pathwayGO:0002429450.240
Mouse
immunoglobulin transcytosis in epithelial cellsGO:000241410.240
negative regulation of kinase activityGO:00336731060.240
Mouse
innate immune responseGO:00450871780.239
Mouse
negative regulation of lymphocyte mediated immunityGO:0002707120.235
Mouse
regulation of cytokine secretionGO:0050707570.232
cellular ion homeostasisGO:00068731680.232
Mouse
signal transduction by phosphorylationGO:00230142970.225
positive regulation of blood vessel endothelial cell migrationGO:0043536160.225
angiogenesisGO:00015251470.224
negative regulation of phosphorus metabolic processGO:00105632670.221
regulation of natural killer cell mediated immunityGO:0002715160.220
regulation of lymphocyte differentiationGO:0045619220.215
Mouse
positive regulation of glucose transportGO:0010828170.215
Human
positive regulation of alpha beta t cell differentiationGO:004663840.214
regulation of b cell activationGO:0050864240.213
Mouse
negative regulation of map kinase activityGO:0043407270.213
Mouse
reactive nitrogen species metabolic processGO:200105730.210
regulation of defense response to virus by hostGO:0050691220.208
positive regulation of immunoglobulin productionGO:000263940.207
jak stat cascadeGO:0007259460.207
interleukin 10 productionGO:0032613170.206
endocytosisGO:00068971590.202
Fly
regulation of transferase activityGO:00513383550.199
Mouse
monosaccharide metabolic processGO:0005996740.199
coagulationGO:0050817780.196
Mouse
cellular homeostasisGO:00197251960.195
Mouse
regulation of adaptive immune responseGO:0002819330.194
Mouse
regulation of endocytosisGO:0030100720.193
negative regulation of intracellular signal transductionGO:19025321830.193
Mouse
regulation of cytokine secretion involved in immune responseGO:000273970.190
response to peptide hormoneGO:0043434610.189
Human
negative regulation of type i interferon productionGO:003248050.189
secretion by cellGO:00329402260.189
regulation of interferon beta productionGO:0032648220.188
regulation of b cell differentiationGO:004557720.188
Mouse
long term memoryGO:000761620.187
energy reserve metabolic processGO:0006112220.183
small molecule biosynthetic processGO:00442831570.182
regulation of cellular response to stressGO:00801352440.182
blood vessel endothelial cell migrationGO:0043534420.180
cortisol secretionGO:004340040.180
regulation of t cell mediated immunityGO:0002709180.179
positive regulation of protein phosphorylationGO:00019343130.179
tyrosine phosphorylation of stat proteinGO:0007260330.179
regulation of serotonin secretionGO:001406210.178
regulation of dna metabolic processGO:00510521530.176
regulation of hemostasisGO:1900046420.176
regulation of phosphate transportGO:001096630.175
regulation of tumor necrosis factor productionGO:0032680430.174
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002824190.174
negative regulation of secretionGO:0051048580.174
positive regulation of endothelial cell migrationGO:0010595390.173
phagocytosis engulfmentGO:000691170.172
Fly
cellular response to oxygen containing compoundGO:19017012760.171
Human
positive regulation of phosphorylationGO:00423273940.170
cell junction organizationGO:0034330790.167
neuron projection developmentGO:00311751060.166
leukocyte degranulationGO:0043299110.163
response to virusGO:00096151260.163
negative regulation of transferase activityGO:00513481240.163
Mouse
epithelium migrationGO:00901321190.162
Fly
hematopoietic progenitor cell differentiationGO:0002244380.160
Mouse
regulation of tumor necrosis factor superfamily cytokine productionGO:1903555440.160
negative regulation of calcium ion transportGO:0051926190.159
neuromuscular junction developmentGO:000752830.159
t cell selectionGO:004505840.158
small gtpase mediated signal transductionGO:0007264780.157
positive regulation of protein kinase b signalingGO:0051897420.156
positive regulation of regulated secretory pathwayGO:190330780.156
cellular response to dna damage stimulusGO:00069743790.156
single organism carbohydrate metabolic processGO:00447231930.154
cell cycle phase transitionGO:00447701730.154
regulation of protein secretionGO:0050708860.153
regulation of epithelial cell migrationGO:0010632930.153
positive regulation of isotype switchingGO:004583020.153
cellular response to peptide hormone stimulusGO:0071375560.152
Human
response to oxygen containing compoundGO:19017003690.152
Human
negative regulation of antigen processing and presentationGO:000257850.148
growthGO:00400072020.147
positive regulation of alpha beta t cell activationGO:0046635100.146
positive regulation of cellular component organizationGO:00511303760.145
leukocyte activation involved in immune responseGO:0002366300.144
cytokine mediated signaling pathwayGO:00192211090.144
heterotypic cell cell adhesionGO:0034113280.143
granulocyte migrationGO:0097530400.141
cytokine metabolic processGO:0042107380.139
regulation of coagulationGO:0050818440.137
cellular response to endogenous stimulusGO:00714953360.137
Human Fly
neuron differentiationGO:00301821380.136
Fly
positive regulation of protein serine threonine kinase activityGO:00719021190.135
cellular response to hormone stimulusGO:00328701250.135
Human
regulation of phagocytosisGO:0050764210.135
response to growth hormoneGO:0060416110.135
taxisGO:00423301570.133
regulation of secretionGO:00510461940.132
cellular response to insulin stimulusGO:0032869410.132
Human
t cell proliferationGO:0042098450.130
Mouse
tyrosine phosphorylation of stat5 proteinGO:0042506130.130
female gamete generationGO:000729220.129
Fly
establishment of protein localization to organelleGO:00725941720.129
negative regulation of immune effector processGO:0002698380.128
Mouse
protein catabolic processGO:00301633250.127
positive regulation of catabolic processGO:00098963100.126
lipid transportGO:0006869900.125
cation homeostasisGO:00550801890.124
Mouse
response to estrogenGO:0043627470.124
negative regulation of phosphorylationGO:00423261740.124
protein autophosphorylationGO:00467771230.124
negative regulation of interleukin 12 secretionGO:200118310.124
type i interferon productionGO:0032606270.122
positive regulation of homeostatic processGO:0032846470.120
cell adhesionGO:00071553250.120
Human Mouse
osteoclast developmentGO:003603520.120
regulation of nervous system developmentGO:0051960880.119
Fly
regulation of cytokine productionGO:00018172320.119
nucleocytoplasmic transportGO:00069131760.119
leukotriene metabolic processGO:0006691100.118
regulation of mast cell activationGO:003300350.117
apoptotic signaling pathwayGO:00971902680.117
single organism cell adhesionGO:00986021790.114
Mouse
negative regulation of cellular protein metabolic processGO:00322693530.113
regulation of cell projection organizationGO:00313441070.112
chemical homeostasisGO:00488783060.111
Mouse
stress activated protein kinase signaling cascadeGO:0031098940.111
negative regulation of transforming growth factor beta secretionGO:200120210.111
ameboidal type cell migrationGO:00016671350.110
Fly
regulation of cell motilityGO:20001452990.109
reproductive processGO:00224141060.109
Human Fly
regulation of calcium ion transport into cytosolGO:0010522330.108
Mouse
negative regulation of cytokine productionGO:0001818820.107
ras protein signal transductionGO:0007265730.106
positive regulation of cell cycleGO:00457871400.105
immune response activating signal transductionGO:0002757900.105
Mouse
protein maturationGO:00516042330.104
negative regulation of cell cycleGO:00457861930.103
positive regulation of epithelial cell migrationGO:0010634550.102
midbrain developmentGO:0030901450.102
cellular response to organonitrogen compoundGO:00714171240.101
Human
stem cell differentiationGO:0048863930.101
response to peptideGO:1901652650.100
Human
epithelial cell migrationGO:00106311190.100
Fly
myeloid cell homeostasisGO:0002262340.099
regulation of regulated secretory pathwayGO:1903305100.098
organ morphogenesisGO:00098871470.097
Fly
heart developmentGO:0007507950.097
Human
endothelial cell proliferationGO:0001935650.097
cytokine secretionGO:0050663640.096
positive regulation of cell migration involved in sprouting angiogenesisGO:009005030.096
reactive oxygen species biosynthetic processGO:190340940.095
positive regulation of cell motilityGO:20001471770.095
cytolysisGO:001983580.095
ephrin receptor signaling pathwayGO:0048013150.095
Human
response to molecule of bacterial originGO:0002237820.094
negative regulation of natural killer cell mediated cytotoxicityGO:004595350.093
positive regulation of cytokine biosynthetic processGO:0042108250.092
cellular metal ion homeostasisGO:00068751460.092
Mouse
protein modification by small protein conjugationGO:00324463420.092
cellular response to cytokine stimulusGO:00713451810.090
thymic t cell selectionGO:004506120.090
fc receptor signaling pathwayGO:003809320.089
myeloid cell activation involved in immune responseGO:0002275100.089
response to bacteriumGO:00096171440.088
regulation of leukocyte mediated cytotoxicityGO:0001910190.087
inositol lipid mediated signalingGO:0048017550.087
positive regulation of exocytosisGO:0045921350.087
b cell receptor signaling pathwayGO:0050853180.087
Mouse
negative regulation of activation of jak2 kinase activityGO:190256910.086
positive regulation of cytokine productionGO:00018191670.085
negative regulation of mononuclear cell proliferationGO:0032945150.084
Mouse
positive regulation of neuron projection developmentGO:0010976340.083
regulation of cell shapeGO:0008360480.083
regulation of system processGO:00440571010.082
neurogenesisGO:00220081690.082
Fly
cellular polysaccharide metabolic processGO:0044264270.082
positive regulation of leukocyte mediated immunityGO:0002705240.082
t cell activation involved in immune responseGO:0002286130.081
regulation of growthGO:00400081650.081
regulation of sequence specific dna binding transcription factor activityGO:00510902110.081
regulation of response to woundingGO:19030341010.080
jnk cascadeGO:0007254800.080
cellular response to growth factor stimulusGO:00713631970.080
Fly
neutrophil apoptotic processGO:000178120.080
neutrophil mediated immunityGO:000244640.080
cellular macromolecular complex assemblyGO:00346223240.079
developmental growthGO:0048589480.078
regulation of homeostatic processGO:00328441210.078
Mouse
mitotic cell cycle processGO:19030472860.077
negative regulation of cytokine mediated signaling pathwayGO:0001960220.076
neuron developmentGO:00486661130.076
Fly
type 2 immune responseGO:004209260.075
negative regulation of cytokine production involved in immune responseGO:0002719130.075
cellular response to peptideGO:1901653590.075
Human
modification dependent macromolecule catabolic processGO:00436322120.074
alcohol metabolic processGO:00060661140.074
immunoglobulin biosynthetic processGO:000237820.074
regulation of cell cell adhesionGO:0022407570.074
positive regulation of jnk cascadeGO:0046330520.073
antigen receptor mediated signaling pathwayGO:0050851380.073
Mouse
regulation of jnk cascadeGO:0046328730.072
response to drugGO:0042493810.072
regulation of gtp catabolic processGO:00331241800.072
regulation of vesicle mediated transportGO:00606271300.071

PTPN6 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
respiratory system diseaseDOID:1579140.953
lower respiratory tract diseaseDOID:0050161130.953
immune system diseaseDOID:29141550.881
lung diseaseDOID:85090.785