Homo sapiens

126 known processes

STUB1

STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase

(Aliases: HSPABP2,CHIP,UBOX1,SDCCAG7,NY-CO-7)

STUB1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
protein ubiquitinationGO:00165673141.000
protein modification by small protein conjugationGO:00324463420.999
modification dependent protein catabolic processGO:00199412090.994
protein refoldingGO:0042026140.991
chaperone cofactor dependent protein refoldingGO:007038940.972
modification dependent macromolecule catabolic processGO:00436322120.948
positive regulation of programmed cell deathGO:00430682490.919
cellular protein catabolic processGO:00442572610.898
protein polyubiquitinationGO:00002091100.889
proteolysis involved in cellular protein catabolic processGO:00516032440.880
negative regulation of apoptotic processGO:00430663160.864
protein catabolic processGO:00301633250.846
cellular macromolecule catabolic processGO:00442653800.839
positive regulation of apoptotic processGO:00430652460.827
positive regulation of cell deathGO:00109422630.805
regulation of protein modification by small protein conjugation or removalGO:19033201070.789
positive regulation of proteolysisGO:00458621420.773
negative regulation of cell deathGO:00605483450.745
regulation of jnk cascadeGO:0046328730.682
regulation of proteolysis involved in cellular protein catabolic processGO:1903050910.669
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.531
response to abiotic stimulusGO:00096283360.507
regulation of protein kinase activityGO:00458592890.483
mapk cascadeGO:00001652880.478
regulation of cellular response to stressGO:00801352440.470
ubiquitin dependent protein catabolic processGO:00065112060.470
regulation of stress activated protein kinase signaling cascadeGO:0070302850.461
jnk cascadeGO:0007254800.425
positive regulation of cysteine type endopeptidase activityGO:2001056790.392
protein foldingGO:0006457380.389
negative regulation of protein modification processGO:00314002000.376
positive regulation of cell cycleGO:00457871400.374
regulation of cell cycleGO:00517263930.370
regulation of proteolysisGO:00301622930.346
nervous system developmentGO:00073992930.340
negative regulation of cellular protein metabolic processGO:00322693530.335
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.327
cellular ketone metabolic processGO:0042180800.322
response to topologically incorrect proteinGO:0035966290.314
positive regulation of cellular catabolic processGO:00313312840.305
regulation of kinase activityGO:00435493140.295
negative regulation of protein phosphorylationGO:00019331400.294
regulation of defense responseGO:00313471540.290
de novo protein foldingGO:000645820.290
female gamete generationGO:000729220.289
negative regulation of cell proliferationGO:00082852280.284
cellular response to topologically incorrect proteinGO:0035967190.281
cellular response to dna damage stimulusGO:00069743790.276
apoptotic signaling pathwayGO:00971902680.264
purine nucleoside triphosphate metabolic processGO:00091444120.254
regulation of proteasomal protein catabolic processGO:0061136870.247
nucleoside monophosphate metabolic processGO:00091231910.244
growthGO:00400072020.244
positive regulation of cellular amine metabolic processGO:003324070.238
positive regulation of i kappab kinase nf kappab signalingGO:00431231320.236
chromatin modificationGO:00165682980.232
multi organism cellular processGO:00447641560.232
positive regulation of protein modification by small protein conjugation or removalGO:1903322610.229
cell type specific apoptotic processGO:00972851250.218
negative regulation of cell cycleGO:00457861930.213
protein k48 linked ubiquitinationGO:0070936380.205
negative regulation of phosphorylationGO:00423261740.204
protein targeting to mitochondrionGO:0006626190.201
defense responseGO:00069523150.195
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280690.188
regulation of protein ubiquitinationGO:0031396950.187
i kappab kinase nf kappab signalingGO:00072491660.184
regulation of mapk cascadeGO:00434082620.184
generation of neuronsGO:00486991520.183
purine nucleoside monophosphate metabolic processGO:00091261860.172
negative regulation of programmed cell deathGO:00430693210.170
regulation of endopeptidase activityGO:00525481700.159
regulation of cell differentiationGO:00455953930.159
purine nucleoside catabolic processGO:00061523980.156
purine ribonucleotide catabolic processGO:00091544040.154
regulation of peptidase activityGO:00525471800.153
stress activated protein kinase signaling cascadeGO:0031098940.152
regulation of immune responseGO:00507762010.150
regulation of nucleotide catabolic processGO:00308112050.148
intrinsic apoptotic signaling pathwayGO:00971931270.145
response to nitrogen compoundGO:19016981840.144
oogenesisGO:004847720.143
srp dependent cotranslational protein targeting to membraneGO:000661420.142
negative regulation of apoptotic signaling pathwayGO:2001234970.138
cellular component morphogenesisGO:00329893140.138
Worm
regulation of i kappab kinase nf kappab signalingGO:00431221620.138
negative regulation of protein metabolic processGO:00512483910.137
protein oligomerizationGO:00512591730.137
cellular protein complex assemblyGO:00436231880.136
negative regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:2001240160.130
immune responseGO:00069553070.122
response to lipidGO:00339932060.120
regulation of mitotic cell cycleGO:00073461890.120
regulation of cellular protein catabolic processGO:1903362960.119
positive regulation of catabolic processGO:00098963100.119
negative regulation of phosphate metabolic processGO:00459362670.115
peptidyl serine modificationGO:00182091060.115
dna damage checkpointGO:0000077680.109
cell projection organizationGO:00300302520.109
regulation of cellular amine metabolic processGO:0033238110.107
proteasomal protein catabolic processGO:00104981760.105
regulation of cell growthGO:00015581350.104
regulation of cellular ketone metabolic processGO:0010565500.104
positive regulation of neuron apoptotic processGO:004352580.103
de novo posttranslational protein foldingGO:005108420.100
cell developmentGO:00484683280.100
Worm
purine ribonucleoside catabolic processGO:00461303980.099
establishment of protein localization to membraneGO:00901501210.095
protein localization to organelleGO:00333652800.093
positive regulation of protein kinase activityGO:00458601900.091
positive regulation of cellular amino acid metabolic processGO:004576430.089
regulation of stress activated mapk cascadeGO:0032872840.089
positive regulation of phosphorylationGO:00423273940.089
neuron apoptotic processGO:0051402390.087
regulation of protein localizationGO:00328802960.087
positive regulation of bindingGO:0051099450.086
positive regulation of cell differentiationGO:00455972110.085
cell cycle checkpointGO:00000751170.085
purine ribonucleoside triphosphate catabolic processGO:00092073910.083
regulation of protein catabolic processGO:00421761550.083
regulation of cellular amino acid metabolic processGO:000652160.083
reproductive processGO:00224141060.083
Worm
regulation of apoptotic signaling pathwayGO:20012331750.083
multicellular organismal agingGO:001025930.082
neuron differentiationGO:00301821380.080
determination of adult lifespanGO:000834020.080
cell growthGO:00160491600.080
regulation of response to dna damage stimulusGO:2001020940.079
neurogenesisGO:00220081690.078
response to oxygen containing compoundGO:19017003690.076
establishment of protein localization to mitochondrionGO:0072655220.076
purine containing compound catabolic processGO:00725234110.075
negative regulation of neuron deathGO:1901215320.074
regulation of purine nucleotide metabolic processGO:19005422640.074
extrinsic apoptotic signaling pathwayGO:00971911190.073
response to cytokineGO:00340972320.072
regulation of neuron apoptotic processGO:0043523350.071
ribonucleoside triphosphate metabolic processGO:00091994120.071
cellular response to misfolded proteinGO:007121820.070
ribonucleotide catabolic processGO:00092614050.069
symbiosis encompassing mutualism through parasitismGO:00444031560.068
positive regulation of developmental processGO:00510943140.068
peptidyl serine phosphorylationGO:00181051010.068
protein autophosphorylationGO:00467771230.067
negative regulation of neuron apoptotic processGO:0043524230.066
single organism reproductive processGO:0044702980.065
signal transduction by phosphorylationGO:00230142970.065
regulation of cell cycle processGO:00105642660.064
purine nucleotide catabolic processGO:00061954050.063
positive regulation of protein phosphorylationGO:00019343130.063
g2 dna damage checkpointGO:0031572260.063
purine ribonucleoside monophosphate catabolic processGO:00091691580.062
regulation of cytokine productionGO:00018172320.062
negative regulation of phosphorus metabolic processGO:00105632670.062
regulation of map kinase activityGO:00434051080.060
response to growth factorGO:00708482050.060
positive regulation of peptidase activityGO:0010952880.058
positive regulation of transferase activityGO:00513472270.058
Mouse
negative regulation of mitotic cell cycleGO:00459301020.057
trna modificationGO:0006400100.057
neuron deathGO:0070997650.055
amine metabolic processGO:0009308440.055
actin cytoskeleton organizationGO:00300362070.054
Worm
immune response activating signal transductionGO:0002757900.053
regulation of nucleoside metabolic processGO:00091182090.053
positive regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032436300.052
response to organonitrogen compoundGO:00102431560.052
negative regulation of catalytic activityGO:00430863350.047
rna modificationGO:0009451270.047
ras protein signal transductionGO:0007265730.046
regulation of symbiosis encompassing mutualism through parasitismGO:00439031090.046
tor signalingGO:0031929390.046
regulation of transferase activityGO:00513383550.045
Mouse
positive regulation of organelle organizationGO:00106381950.045
actin filament based processGO:00300292240.045
Worm
dna integrity checkpointGO:0031570710.044
response to light stimulusGO:0009416870.044
negative regulation of cell cycle phase transitionGO:1901988890.043
positive regulation of hydrolase activityGO:00513453310.043
regulation of growthGO:00400081650.043
negative regulation of intracellular signal transductionGO:19025321830.043
positive regulation of neurogenesisGO:0050769490.042
cell adhesionGO:00071553250.042
intracellular protein transmembrane transportGO:0065002240.042
ribonucleoside triphosphate catabolic processGO:00092033910.042
stress activated mapk cascadeGO:0051403930.042
single organism cellular localizationGO:19025803320.042
regulation of extrinsic apoptotic signaling pathwayGO:2001236850.042
regulation of response to external stimulusGO:00321012220.040
regulation of protein serine threonine kinase activityGO:00719001790.040
cell projection morphogenesisGO:00488581290.040
positive regulation of immune responseGO:00507781590.039
nucleoside triphosphate metabolic processGO:00091414220.039
cellular macromolecular complex assemblyGO:00346223240.039
innate immune responseGO:00450871780.039
positive regulation of proteasomal protein catabolic processGO:1901800350.039
positive regulation of neuron differentiationGO:0045666400.038
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434710.038
regulation of locomotionGO:00400123290.037
establishment of protein localization to organelleGO:00725941720.037
positive regulation of cellular component organizationGO:00511303760.036
cell morphogenesisGO:00009022960.036
response to metal ionGO:0010038840.036
positive regulation of cytokine productionGO:00018191670.035
negative regulation of protein processingGO:00109551420.035
purine ribonucleoside monophosphate metabolic processGO:00091671860.035
positive regulation of nucleotide catabolic processGO:00308131850.035
ribonucleoside catabolic processGO:00424544060.034
oocyte developmentGO:004859910.034
positive regulation of cell developmentGO:0010720920.034
regulation of protein maturationGO:19033171500.033
embryonic placenta developmentGO:000189210.032
cotranslational protein targeting to membraneGO:000661320.032
vesicle mediated transportGO:00161923710.032
histone modificationGO:00165702510.032
purine nucleoside triphosphate catabolic processGO:00091463920.032
response to lithium ionGO:001022620.031
immune response regulating signaling pathwayGO:0002764970.031
cellular response to growth factor stimulusGO:00713631970.031
ribonucleoside monophosphate catabolic processGO:00091581580.030
nucleoside catabolic processGO:00091644080.030
dna repairGO:00062811980.029
negative regulation of protein kinase activityGO:0006469980.029
cell morphogenesis involved in differentiationGO:00009041440.029
axonogenesisGO:0007409310.028
regulation of cell migrationGO:00303342890.028
response to unfolded proteinGO:0006986240.028
Mouse
regulation of microtubule polymerization or depolymerizationGO:0031110270.028
protein targeting to membraneGO:0006612420.028
locomotory behaviorGO:000762610.028
neuromuscular junction developmentGO:000752830.027
negative regulation of proteolysisGO:00458611320.027
cell cell signalingGO:00072671550.027
negative regulation of cellular component organizationGO:00511292350.027
protein polymerizationGO:0051258710.027
regulation of cysteine type endopeptidase activityGO:20001161270.026
regulation of tor signalingGO:0032006300.026
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.026
positive regulation of kinase activityGO:00336742040.026
positive regulation of nucleotide metabolic processGO:00459812300.026
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781250.025
autophagyGO:0006914880.025
regulation of neuron deathGO:1901214560.025
negative regulation of cysteine type endopeptidase activityGO:2000117480.025
carbohydrate derivative biosynthetic processGO:19011372070.024
response to other organismGO:00517072610.024
chromatin organizationGO:00063253510.024
regulation of cell motilityGO:20001452990.024
positive regulation of neuron projection developmentGO:0010976340.024
posttranscriptional regulation of gene expressionGO:00106082130.023
gtp catabolic processGO:00061842370.023
regulation of intrinsic apoptotic signaling pathwayGO:2001242720.023
positive regulation of peptidyl tyrosine phosphorylationGO:0050731850.023
skin developmentGO:0043588760.023
mitochondrial transportGO:0006839600.023
positive regulation of locomotionGO:00400171860.023
inflammatory responseGO:0006954790.023
positive regulation of protein polymerizationGO:0032273450.022
cellular amino acid metabolic processGO:00065201160.022
negative regulation of protein modification by small protein conjugation or removalGO:1903321410.022
negative regulation of striated muscle cell apoptotic processGO:001066420.022
small gtpase mediated signal transductionGO:0007264780.022
response to misfolded proteinGO:005178850.022
negative regulation of growthGO:0045926970.022
protein depolymerizationGO:0051261300.022
tube developmentGO:00352951250.022
response to nutrient levelsGO:0031667810.022
cell activationGO:00017752130.021
positive regulation of nervous system developmentGO:0051962540.021
positive regulation of endopeptidase activityGO:0010950840.021
regulation of cell morphogenesisGO:00226041530.021
retrograde transport endosome to golgiGO:0042147450.021
regulation of innate immune responseGO:0045088970.021
regulation of homeostatic processGO:00328441210.020
zymogen activationGO:0031638700.020
inclusion body assemblyGO:0070841170.020
enzyme linked receptor protein signaling pathwayGO:00071673030.020
regulation of nucleotide metabolic processGO:00061402690.020
mitotic cell cycleGO:00002783260.020
positive regulation of map kinase activityGO:0043406800.020
microtubule cytoskeleton organizationGO:00002261760.020
gtp metabolic processGO:00460392390.019
response to temperature stimulusGO:0009266220.019
regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:2001239200.019
regulation of microtubule based processGO:0032886740.019
negative regulation of cellular amino acid metabolic processGO:004576320.019
microtubule based processGO:00070172100.019
negative regulation of cell cycle processGO:00109481210.019
regulation of protein polymerizationGO:0032271630.018
organophosphate catabolic processGO:00464344300.018
cell part morphogenesisGO:00329901370.018
intracellular protein transportGO:00068862700.018
negative regulation of hydrolase activityGO:00513461820.018
heat acclimationGO:001028630.018
cellular amine metabolic processGO:0044106410.017
negative regulation of intrinsic apoptotic signaling pathwayGO:2001243400.017
negative regulation of kinase activityGO:00336731060.017
nucleotide catabolic processGO:00091664080.017
regulation of inclusion body assemblyGO:0090083130.017
multi organism reproductive processGO:0044703540.017
Worm
chaperone mediated protein foldingGO:0061077130.017
regulation of neuron differentiationGO:0045664700.017
regulation of protein complex assemblyGO:00432541470.017
cell morphogenesis involved in neuron differentiationGO:0048667440.017
purine ribonucleoside metabolic processGO:00461284370.017
regulation of cellular component biogenesisGO:00440872810.017
head developmentGO:00603221080.017
small molecule biosynthetic processGO:00442831570.017
nitrogen compound transportGO:00717051910.016
regulation of anatomical structure morphogenesisGO:00226032860.016
mitotic cell cycle processGO:19030472860.016
striated muscle myosin thick filament assemblyGO:007168820.016
regulation of atp metabolic processGO:1903578290.016
negative regulation of peptidase activityGO:0010466910.016
female pregnancyGO:0007565170.016
regulation of viral processGO:00507921030.016
establishment or maintenance of cell polarityGO:0007163310.016
response to drugGO:0042493810.016
activation of cysteine type endopeptidase activity involved in apoptotic processGO:0006919490.016
central nervous system developmentGO:00074171230.016
endocytosisGO:00068971590.015
neuron developmentGO:00486661130.015
er associated ubiquitin dependent protein catabolic processGO:0030433310.015
cellular response to cytokine stimulusGO:00713451810.015
internal protein amino acid acetylationGO:00064751010.015
reproductionGO:0000003630.015
Worm
negative regulation of fibril organizationGO:190290410.015
response to oxidative stressGO:00069791210.015
protein deubiquitinationGO:0016579790.015
post embryonic developmentGO:000979120.015
Worm
glycosyl compound catabolic processGO:19016584130.015
multicellular organism reproductionGO:0032504420.015
Worm
axon cargo transportGO:000808820.015
blood vessel morphogenesisGO:00485141620.014
regulation of ion transportGO:00432691890.014
metal ion transportGO:00300012720.014
macropinocytosisGO:004435110.014
protein acetylationGO:00064731160.014
regulation of transcription during mitosisGO:004589620.014
regulation of protein processingGO:00706131500.014
nuclear transportGO:00511691790.014
positive regulation of stress activated mapk cascadeGO:0032874600.014
positive regulation of cell sizeGO:004579330.013
nucleic acid phosphodiester bond hydrolysisGO:00903051020.013
cellular response to external stimulusGO:00714961110.013
protein localization to membraneGO:00726571600.013
regulation of cytoskeleton organizationGO:00514931770.013
embryo developmentGO:00097901230.013
protein targetingGO:00066051870.012
negative regulation of map kinase activityGO:0043407270.012
regulation of cell projection organizationGO:00313441070.012
positive regulation of dna bindingGO:0043388170.012
myosin filament organizationGO:003103320.012
embryo development ending in birth or egg hatchingGO:0009792340.012
translationGO:00064121320.012
negative regulation of cell growthGO:0030308830.012
trna processingGO:0008033230.012
regulation of peptidyl tyrosine phosphorylationGO:00507301080.011
regulation of secretion by cellGO:19035301770.011
response to hormoneGO:00097251750.011
ribonucleoside monophosphate metabolic processGO:00091611870.011
viral life cycleGO:00190581320.011
receptor mediated endocytosisGO:0006898840.011
positive regulation of nf kappab transcription factor activityGO:0051092810.011
protein homooligomerizationGO:00512601000.011
positive regulation of cell projection organizationGO:0031346640.011
regulation of ras protein signal transductionGO:00465781550.011
response to fungusGO:000962040.011
purine ribonucleoside triphosphate metabolic processGO:00092054110.011
metencephalon developmentGO:002203720.011
spermatid differentiationGO:004851540.011
nuclear divisionGO:00002801280.011
negative regulation of microtubule polymerization or depolymerizationGO:0031111170.011
regulation of cell cycle phase transitionGO:19019871260.011
response to decreased oxygen levelsGO:0036293960.011
axon developmentGO:0061564340.011
positive regulation of meiotic cell cycleGO:005144620.010
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092900.010
regulation of nervous system developmentGO:0051960880.010
immune system developmentGO:00025201950.010
apoptotic mitochondrial changesGO:0008637570.010
neuroblast proliferationGO:000740540.010
adult locomotory behaviorGO:000834410.010

STUB1 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
muscular diseaseDOID:00800001140.394
muscle tissue diseaseDOID:661130.394
musculoskeletal system diseaseDOID:172230.394
myopathyDOID:4231040.063
nervous system diseaseDOID:8634310.060
central nervous system diseaseDOID:3311860.060
neurodegenerative diseaseDOID:12891020.060