IMP: Integrative Multi-species Prediction

Homo sapiens

0 known processes

PTDSS1

phosphatidylserine synthase 1

(Aliases: KIAA0024,PSSA,PSS1)

Entrez: 9791
HGNC: 9587
Ensembl: ENSG00000156471
MIM: 612792
HPRD: 17926
UniProtKB: P48651

Process Predictions
Disease Predictions

PTDSS1 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
post embryonic development	GO:0009791	2	0.351
vesicle mediated transport	GO:0016192	371	0.143
nucleotide biosynthetic process	GO:0009165	109	0.116
organonitrogen compound biosynthetic process	GO:1901566	200	0.107
female gamete generation	GO:0007292	2	0.105
nucleoside phosphate biosynthetic process	GO:1901293	109	0.098
cellular macromolecular complex assembly	GO:0034622	324	0.088
organic anion transport	GO:0015711	103	0.084
carbohydrate derivative biosynthetic process	GO:1901137	207	0.083
cell development	GO:0048468	328	0.081
ribose phosphate biosynthetic process	GO:0046390	82	0.076
regulation of oxidative phosphorylation	GO:0002082	3	0.075
lipid transport	GO:0006869	90	0.072
cellular amino acid metabolic process	GO:0006520	116	0.071
nucleoside monophosphate metabolic process	GO:0009123	191	0.070
purine ribonucleoside metabolic process	GO:0046128	437	0.067
chemical homeostasis	GO:0048878	306	0.066
cellular amine metabolic process	GO:0044106	41	0.062
positive regulation of developmental process	GO:0051094	314	0.060	Worm
oogenesis	GO:0048477	2	0.058
endocytosis	GO:0006897	159	0.055
negative regulation of multicellular organismal process	GO:0051241	317	0.053
alpha amino acid metabolic process	GO:1901605	72	0.051
negative regulation of programmed cell death	GO:0043069	321	0.046
single organism carbohydrate metabolic process	GO:0044723	193	0.046
multicellular organismal aging	GO:0010259	3	0.046
cell adhesion	GO:0007155	325	0.045
nucleoside triphosphate metabolic process	GO:0009141	422	0.042
cellular protein complex assembly	GO:0043623	188	0.039
ribonucleoside monophosphate metabolic process	GO:0009161	187	0.038
regulation of anatomical structure morphogenesis	GO:0022603	286	0.038
system process	GO:0003008	349	0.037
purine ribonucleotide biosynthetic process	GO:0009152	79	0.037
locomotory behavior	GO:0007626	1	0.037
determination of adult lifespan	GO:0008340	2	0.036
amine metabolic process	GO:0009308	44	0.036
epithelium development	GO:0060429	227	0.036
anion transport	GO:0006820	161	0.034
biological adhesion	GO:0022610	331	0.034
carbohydrate metabolic process	GO:0005975	207	0.033
glycoprotein metabolic process	GO:0009100	110	0.033
cellular ion homeostasis	GO:0006873	168	0.032
purine nucleotide biosynthetic process	GO:0006164	84	0.032
cellular cation homeostasis	GO:0030003	163	0.032
actin filament based process	GO:0030029	224	0.031
cellular homeostasis	GO:0019725	196	0.031
embryo development	GO:0009790	123	0.031
mitotic cell cycle process	GO:1903047	286	0.031
cellular component morphogenesis	GO:0032989	314	0.031
negative regulation of phosphate metabolic process	GO:0045936	267	0.030
cellular metal ion homeostasis	GO:0006875	146	0.029
negative regulation of apoptotic process	GO:0043066	316	0.029
single organism membrane organization	GO:0044802	268	0.029
regulation of cell differentiation	GO:0045595	393	0.029
ribonucleoside triphosphate metabolic process	GO:0009199	412	0.029
anatomical structure formation involved in morphogenesis	GO:0048646	284	0.028
cellular response to dna damage stimulus	GO:0006974	379	0.028
adult locomotory behavior	GO:0008344	1	0.028
single organism cellular localization	GO:1902580	332	0.027
cellular chemical homeostasis	GO:0055082	180	0.027
cation transmembrane transport	GO:0098655	238	0.027
positive regulation of cell proliferation	GO:0008284	301	0.026
response to abiotic stimulus	GO:0009628	336	0.026
apoptotic signaling pathway	GO:0097190	268	0.026
regulation of nucleotide metabolic process	GO:0006140	269	0.026
negative regulation of protein metabolic process	GO:0051248	391	0.025
metal ion homeostasis	GO:0055065	169	0.025
mitotic cell cycle	GO:0000278	326	0.024
nucleic acid phosphodiester bond hydrolysis	GO:0090305	102	0.024
reproductive process	GO:0022414	106	0.024
neuron differentiation	GO:0030182	138	0.024
negative regulation of cell death	GO:0060548	345	0.023
cellular modified amino acid metabolic process	GO:0006575	64	0.023
negative regulation of cellular component organization	GO:0051129	235	0.023
ion transmembrane transport	GO:0034220	338	0.023
cation transport	GO:0006812	331	0.023
positive regulation of cellular component organization	GO:0051130	376	0.023
organophosphate biosynthetic process	GO:0090407	163	0.023
translation	GO:0006412	132	0.023
regulation of cell cycle process	GO:0010564	266	0.023
intracellular protein transport	GO:0006886	270	0.023
growth	GO:0040007	202	0.023	Worm
negative regulation of catalytic activity	GO:0043086	335	0.022
glycosylation	GO:0070085	71	0.022
alpha amino acid catabolic process	GO:1901606	26	0.022
nucleoside biosynthetic process	GO:0009163	26	0.022
metal ion transport	GO:0030001	272	0.021
regulation of kinase activity	GO:0043549	314	0.021
glutamine family amino acid metabolic process	GO:0009064	17	0.021
negative regulation of developmental process	GO:0051093	247	0.021
regulation of cellular amino acid metabolic process	GO:0006521	6	0.021
small molecule catabolic process	GO:0044282	92	0.021
cation homeostasis	GO:0055080	189	0.020
tissue morphogenesis	GO:0048729	96	0.020
positive regulation of apoptotic process	GO:0043065	246	0.020
dephosphorylation	GO:0016311	209	0.020
dna dealkylation	GO:0035510	13	0.020
cell activation	GO:0001775	213	0.019
organelle assembly	GO:0070925	176	0.019
purine ribonucleoside monophosphate metabolic process	GO:0009167	186	0.019
positive regulation of transport	GO:0051050	336	0.019
positive regulation of sequence specific dna binding transcription factor activity	GO:0051091	131	0.019
photoreceptor cell differentiation	GO:0046530	2	0.019
purine ribonucleoside monophosphate catabolic process	GO:0009169	158	0.019
developmental process involved in reproduction	GO:0003006	66	0.019
single organism reproductive process	GO:0044702	98	0.018
response to other organism	GO:0051707	261	0.018
organ morphogenesis	GO:0009887	147	0.018
negative regulation of phosphorus metabolic process	GO:0010563	267	0.018
hemopoiesis	GO:0030097	180	0.018
membrane organization	GO:0061024	292	0.018
immune response	GO:0006955	307	0.018
regulation of purine nucleotide metabolic process	GO:1900542	264	0.018
negative regulation of cell proliferation	GO:0008285	228	0.018
cell projection organization	GO:0030030	252	0.018
mitotic cell cycle phase transition	GO:0044772	162	0.018
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.018
striated muscle myosin thick filament assembly	GO:0071688	2	0.017
atp metabolic process	GO:0046034	176	0.017
regulation of proteolysis	GO:0030162	293	0.017
inorganic cation transmembrane transport	GO:0098662	194	0.017
generation of neurons	GO:0048699	152	0.017
inorganic ion transmembrane transport	GO:0098660	231	0.017
oocyte development	GO:0048599	1	0.017
purine nucleoside monophosphate metabolic process	GO:0009126	186	0.017
ion homeostasis	GO:0050801	230	0.017
negative regulation of cell cycle	GO:0045786	193	0.017
response to biotic stimulus	GO:0009607	276	0.017
cell morphogenesis	GO:0000902	296	0.017
purine ribonucleoside triphosphate catabolic process	GO:0009207	391	0.017
hindbrain development	GO:0030902	3	0.016
ribonucleotide biosynthetic process	GO:0009260	81	0.016
nucleoside triphosphate catabolic process	GO:0009143	394	0.016
regulation of transmembrane transport	GO:0034762	139	0.016
receptor mediated endocytosis	GO:0006898	84	0.016
single organism nuclear import	GO:1902593	104	0.016
defense response	GO:0006952	315	0.016
positive regulation of peptidase activity	GO:0010952	88	0.016
activation of cysteine type endopeptidase activity involved in apoptotic process	GO:0006919	49	0.016
epithelial cell proliferation	GO:0050673	128	0.016
cellular ketone metabolic process	GO:0042180	80	0.016
purine ribonucleoside triphosphate metabolic process	GO:0009205	411	0.016
cell cycle phase transition	GO:0044770	173	0.015
myosin filament assembly	GO:0031034	2	0.015
receptor metabolic process	GO:0043112	81	0.015
cytoplasmic transport	GO:0016482	379	0.015
response to external biotic stimulus	GO:0043207	261	0.015
regulation of protein localization	GO:0032880	296	0.015
cytokine production	GO:0001816	247	0.015
transmembrane transport	GO:0055085	399	0.015
purine containing compound catabolic process	GO:0072523	411	0.015
positive regulation of cellular amine metabolic process	GO:0033240	7	0.015
regulation of cellular amine metabolic process	GO:0033238	11	0.015
atp catabolic process	GO:0006200	157	0.015
toxin transport	GO:1901998	4	0.015
protein processing	GO:0016485	226	0.015
purine nucleotide catabolic process	GO:0006195	405	0.015
negative regulation of cellular protein metabolic process	GO:0032269	353	0.015
demethylation	GO:0070988	37	0.014
nucleobase biosynthetic process	GO:0046112	4	0.014
protein targeting	GO:0006605	187	0.014
organelle fission	GO:0048285	149	0.014
neurological system process	GO:0050877	163	0.014
regulation of transferase activity	GO:0051338	355	0.014
negative regulation of intracellular signal transduction	GO:1902532	183	0.014
regulation of peptidase activity	GO:0052547	180	0.014
protein glycosylation	GO:0006486	62	0.014
divalent metal ion transport	GO:0070838	152	0.014
cardiovascular system development	GO:0072358	262	0.014
macromolecule glycosylation	GO:0043413	63	0.014
reactive oxygen species metabolic process	GO:0072593	75	0.014
transmembrane receptor protein serine threonine kinase signaling pathway	GO:0007178	125	0.014
response to oxygen containing compound	GO:1901700	369	0.014
glycoprotein biosynthetic process	GO:0009101	91	0.014
regeneration	GO:0031099	4	0.014
i kappab kinase nf kappab signaling	GO:0007249	166	0.014
lipid localization	GO:0010876	106	0.014
establishment of protein localization to organelle	GO:0072594	172	0.014
actin cytoskeleton organization	GO:0030036	207	0.014
eye photoreceptor cell differentiation	GO:0001754	2	0.014
mammary gland morphogenesis	GO:0060443	2	0.014
nucleoside catabolic process	GO:0009164	408	0.013
reproduction	GO:0000003	63	0.013
response to virus	GO:0009615	126	0.013
protein import into nucleus	GO:0006606	104	0.013
cellular lipid metabolic process	GO:0044255	303	0.013
single organism cell adhesion	GO:0098602	179	0.013
positive regulation of purine nucleotide metabolic process	GO:1900544	227	0.013
regulation of sequence specific dna binding transcription factor activity	GO:0051090	211	0.013
purine ribonucleotide catabolic process	GO:0009154	404	0.013
nucleotide catabolic process	GO:0009166	408	0.013
protein autophosphorylation	GO:0046777	123	0.013
neuromuscular junction development	GO:0007528	3	0.013
cellular macromolecule catabolic process	GO:0044265	380	0.013
purine ribonucleoside catabolic process	GO:0046130	398	0.013
hematopoietic or lymphoid organ development	GO:0048534	186	0.013
anterior posterior axis specification	GO:0009948	2	0.013
cellular response to abiotic stimulus	GO:0071214	117	0.013
immune system development	GO:0002520	195	0.013
oocyte differentiation	GO:0009994	2	0.013
innate immune response	GO:0045087	178	0.013
regulation of cell development	GO:0060284	161	0.013
positive regulation of cell differentiation	GO:0045597	211	0.013
circulatory system development	GO:0072359	262	0.012
negative regulation of phosphorylation	GO:0042326	174	0.012
cellular response to cytokine stimulus	GO:0071345	181	0.012
protein maturation	GO:0051604	233	0.012
regulation of cell cycle phase transition	GO:1901987	126	0.012
regulation of cellular ketone metabolic process	GO:0010565	50	0.012
positive regulation of nucleoside metabolic process	GO:0045979	186	0.012
protein targeting to nucleus	GO:0044744	104	0.012
nucleus localization	GO:0051647	1	0.012
blastoderm segmentation	GO:0007350	2	0.012
ribonucleoside monophosphate catabolic process	GO:0009158	158	0.012
regulation of cellular response to stress	GO:0080135	244	0.012
cell aging	GO:0007569	52	0.012
response to radiation	GO:0009314	151	0.012
regulation of cell cycle	GO:0051726	393	0.012
endomembrane system organization	GO:0010256	196	0.012
purine containing compound biosynthetic process	GO:0072522	88	0.012
behavior	GO:0007610	112	0.012
monovalent inorganic cation transport	GO:0015672	128	0.012
maintenance of location	GO:0051235	112	0.012
regulation of nucleoside metabolic process	GO:0009118	209	0.011
glycosyl compound catabolic process	GO:1901658	413	0.011
negative regulation of catabolic process	GO:0009895	104	0.011
protein localization to organelle	GO:0033365	280	0.011
positive regulation of immune response	GO:0050778	159	0.011
rrna modification	GO:0000154	2	0.011
negative regulation of protein modification process	GO:0031400	200	0.011
regulation of viral process	GO:0050792	103	0.011
regulation of intracellular transport	GO:0032386	195	0.011
myosin filament organization	GO:0031033	2	0.011
regulation of establishment of protein localization	GO:0070201	242	0.011
regulation of i kappab kinase nf kappab signaling	GO:0043122	162	0.011
sex differentiation	GO:0007548	45	0.011
response to growth factor	GO:0070848	205	0.011
neuron development	GO:0048666	113	0.011
regulation of epithelial cell proliferation	GO:0050678	113	0.011
ribonucleoside triphosphate catabolic process	GO:0009203	391	0.011
tube development	GO:0035295	125	0.011
positive regulation of cell death	GO:0010942	263	0.011
blood vessel morphogenesis	GO:0048514	162	0.011
purine nucleoside monophosphate biosynthetic process	GO:0009127	16	0.011
positive regulation of immune system process	GO:0002684	283	0.011
positive regulation of catabolic process	GO:0009896	310	0.011
aging	GO:0007568	66	0.011
protein localization to nucleus	GO:0034504	136	0.011
purine nucleoside triphosphate catabolic process	GO:0009146	392	0.011
glycosyl compound biosynthetic process	GO:1901659	27	0.011
protein complex disassembly	GO:0043241	52	0.011
phospholipid metabolic process	GO:0006644	99	0.011
negative regulation of growth	GO:0045926	97	0.011
regulation of cellular component biogenesis	GO:0044087	281	0.011
nucleoside monophosphate catabolic process	GO:0009125	159	0.011
cellular response to lipid	GO:0071396	127	0.011
regulation of nucleotide catabolic process	GO:0030811	205	0.010
microtubule based process	GO:0007017	210	0.010
negative regulation of immune system process	GO:0002683	136	0.010
cellular response to oxygen containing compound	GO:1901701	276	0.010
negative regulation of transferase activity	GO:0051348	124	0.010
nuclear division	GO:0000280	128	0.010
cellular response to radiation	GO:0071478	65	0.010
divalent inorganic cation transport	GO:0072511	158	0.010
purine nucleoside triphosphate metabolic process	GO:0009144	412	0.010
lipid biosynthetic process	GO:0008610	177	0.010
cell substrate adhesion	GO:0031589	132	0.010
regulation of cell growth	GO:0001558	135	0.010
nuclear import	GO:0051170	106	0.010
epithelial cell differentiation	GO:0030855	141	0.010
gmp metabolic process	GO:0046037	4	0.010
regulation of growth	GO:0040008	165	0.010	Worm
neurogenesis	GO:0022008	169	0.010

PTDSS1 disease predictions

Disease	DO term ID	Size	Probability
disease of metabolism	DOID:0014667	295	0.110
inherited metabolic disorder	DOID:655	242	0.109
nervous system disease	DOID:863	431	0.067
central nervous system disease	DOID:331	186	0.067
neurodegenerative disease	DOID:1289	102	0.037
congenital disorder of glycosylation	DOID:5212	26	0.029
carbohydrate metabolic disorder	DOID:2978	55	0.029
organ system cancer	DOID:0050686	164	0.014
disease of cellular proliferation	DOID:14566	174	0.014
cancer	DOID:162	167	0.014
congenital disorder of glycosylation type i	DOID:0050570	16	0.013
immune system disease	DOID:2914	155	0.013
sensory system disease	DOID:0050155	203	0.010

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