Homo sapiens

53 known processes

SIGIRR

single immunoglobulin and toll-interleukin 1 receptor (TIR) domain

(Aliases: MGC110992,TIR8)

SIGIRR biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular ketone metabolic processGO:0042180800.127
cellular amine metabolic processGO:0044106410.091
monocarboxylic acid metabolic processGO:00327871850.084
regulation of cellular ketone metabolic processGO:0010565500.075
cellular amino acid metabolic processGO:00065201160.067
regulation of cellular amine metabolic processGO:0033238110.062
single organism carbohydrate metabolic processGO:00447231930.062
negative regulation of multicellular organismal processGO:00512413170.062
Mouse
cellular lipid metabolic processGO:00442553030.060
amine metabolic processGO:0009308440.060
negative regulation of cellular protein metabolic processGO:00322693530.057
carbohydrate metabolic processGO:00059752070.056
negative regulation of phosphate metabolic processGO:00459362670.052
regulation of locomotionGO:00400123290.051
lipid metabolic processGO:00066293810.049
positive regulation of locomotionGO:00400171860.049
positive regulation of cellular amine metabolic processGO:003324070.046
response to external biotic stimulusGO:00432072610.045
regulation of cellular amino acid metabolic processGO:000652160.043
regulation of cell motilityGO:20001452990.043
enzyme linked receptor protein signaling pathwayGO:00071673030.043
negative regulation of phosphorylationGO:00423261740.041
positive regulation of cellular amino acid metabolic processGO:004576430.040
negative regulation of phosphorus metabolic processGO:00105632670.040
response to abiotic stimulusGO:00096283360.039
negative regulation of cellular component organizationGO:00511292350.039
negative regulation of protein modification processGO:00314002000.038
negative regulation of protein metabolic processGO:00512483910.037
Mouse
cellular response to dna damage stimulusGO:00069743790.037
regulation of hormone levelsGO:00108171250.037
positive regulation of cell migrationGO:00303351720.037
system processGO:00030083490.036
organonitrogen compound biosynthetic processGO:19015662000.035
regulation of transferase activityGO:00513383550.035
response to oxygen containing compoundGO:19017003690.034
positive regulation of cell motilityGO:20001471770.034
regulation of cellular component movementGO:00512703340.034
response to other organismGO:00517072610.034
negative regulation of catalytic activityGO:00430863350.034
ribonucleotide catabolic processGO:00092614050.033
mitotic cell cycleGO:00002783260.033
positive regulation of cellular component movementGO:00512721810.033
purine containing compound catabolic processGO:00725234110.033
glycoprotein metabolic processGO:00091001100.033
positive regulation of transportGO:00510503360.032
positive regulation of purine nucleotide catabolic processGO:00331231850.032
regulation of cell growthGO:00015581350.031
cell adhesionGO:00071553250.031
regulation of anatomical structure morphogenesisGO:00226032860.031
generation of precursor metabolites and energyGO:0006091680.031
response to organic cyclic compoundGO:00140702040.030
lipid biosynthetic processGO:00086101770.030
cellular response to abiotic stimulusGO:00712141170.030
epithelium migrationGO:00901321190.029
negative regulation of protein phosphorylationGO:00019331400.029
regulation of cellular component biogenesisGO:00440872810.029
positive regulation of developmental processGO:00510943140.028
response to biotic stimulusGO:00096072760.028
negative regulation of growthGO:0045926970.028
response to hormoneGO:00097251750.027
positive regulation of phosphorylationGO:00423273940.027
cytokine productionGO:00018162470.027
Mouse
defense responseGO:00069523150.027
Mouse
glycerolipid metabolic processGO:00464861070.027
response to drugGO:0042493810.027
growthGO:00400072020.026
chemical homeostasisGO:00488783060.026
immune responseGO:00069553070.026
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.026
cell growthGO:00160491600.026
secretion by cellGO:00329402260.026
peptidyl tyrosine modificationGO:00182121700.026
organophosphate biosynthetic processGO:00904071630.025
regulation of cell differentiationGO:00455953930.025
negative regulation of developmental processGO:00510932470.025
purine ribonucleoside triphosphate catabolic processGO:00092073910.025
dephosphorylationGO:00163112090.025
purine ribonucleoside triphosphate metabolic processGO:00092054110.024
cellular component morphogenesisGO:00329893140.024
post embryonic developmentGO:000979120.024
organophosphate catabolic processGO:00464344300.024
ras protein signal transductionGO:0007265730.023
regulation of cell migrationGO:00303342890.023
cellular response to endogenous stimulusGO:00714953360.023
ribonucleoside triphosphate metabolic processGO:00091994120.023
regulation of growthGO:00400081650.023
purine nucleotide catabolic processGO:00061954050.023
negative regulation of cell growthGO:0030308830.023
cardiac muscle contractionGO:0060048340.023
response to virusGO:00096151260.022
positive regulation of protein phosphorylationGO:00019343130.022
signal transduction by phosphorylationGO:00230142970.022
female gamete generationGO:000729220.022
positive regulation of organelle organizationGO:00106381950.022
organic hydroxy compound metabolic processGO:19016151470.022
cellular macromolecular complex assemblyGO:00346223240.022
positive regulation of cellular component organizationGO:00511303760.022
response to lipidGO:00339932060.022
small gtpase mediated signal transductionGO:0007264780.022
regulation of kinase activityGO:00435493140.022
tissue migrationGO:00901301190.022
nucleoside triphosphate metabolic processGO:00091414220.022
epithelial cell migrationGO:00106311190.022
negative regulation of cell deathGO:00605483450.022
cellular macromolecule catabolic processGO:00442653800.021
purine nucleoside triphosphate metabolic processGO:00091444120.021
peptidyl tyrosine phosphorylationGO:00181081700.021
regulation of protein complex assemblyGO:00432541470.021
purine nucleoside catabolic processGO:00061523980.021
regulation of proteolysisGO:00301622930.021
positive regulation of cell differentiationGO:00455972110.021
positive regulation of nucleotide metabolic processGO:00459812300.021
regulation of cell morphogenesisGO:00226041530.021
cellular protein catabolic processGO:00442572610.021
response to steroid hormoneGO:0048545800.021
regulation of immune responseGO:00507762010.020
response to growth factorGO:00708482050.020
cellular response to growth factor stimulusGO:00713631970.020
actin filament based processGO:00300292240.020
regulation of purine nucleotide metabolic processGO:19005422640.020
wound healingGO:00420601150.020
positive regulation of cell proliferationGO:00082843010.020
striated muscle contractionGO:0006941520.020
positive regulation of cellular catabolic processGO:00313312840.020
positive regulation of hydrolase activityGO:00513453310.019
positive regulation of cellular component biogenesisGO:00440891580.019
positive regulation of erk1 and erk2 cascadeGO:0070374750.019
multicellular organismal agingGO:001025930.019
purine nucleoside triphosphate catabolic processGO:00091463920.019
cellular response to cytokine stimulusGO:00713451810.018
Human Mouse
negative regulation of immune system processGO:00026831360.018
nucleoside phosphate catabolic processGO:19012924120.018
oxidation reduction processGO:00551143960.018
regulation of nucleotide catabolic processGO:00308112050.018
protein modification by small protein conjugationGO:00324463420.018
muscle contractionGO:0006936730.018
membrane organizationGO:00610242920.018
regulation of protein kinase activityGO:00458592890.018
ameboidal type cell migrationGO:00016671350.018
apoptotic signaling pathwayGO:00971902680.018
regulation of mitotic cell cycleGO:00073461890.018
mapk cascadeGO:00001652880.018
negative regulation of cellular amino acid metabolic processGO:004576320.018
positive regulation of immune system processGO:00026842830.018
erk1 and erk2 cascadeGO:00703711040.017
pyruvate metabolic processGO:0006090260.017
regulation of nucleoside metabolic processGO:00091182090.017
regulation of purine nucleotide catabolic processGO:00331212050.017
vesicle mediated transportGO:00161923710.017
purine ribonucleotide catabolic processGO:00091544040.017
phospholipid metabolic processGO:0006644990.017
cellular protein complex assemblyGO:00436231880.017
biological adhesionGO:00226103310.017
determination of adult lifespanGO:000834020.017
carbohydrate derivative biosynthetic processGO:19011372070.017
cell morphogenesisGO:00009022960.017
glycosyl compound catabolic processGO:19016584130.017
regenerationGO:003109940.017
purine ribonucleoside metabolic processGO:00461284370.017
regulation of cell cycle processGO:00105642660.017
segmentationGO:003528240.017
hormone transportGO:0009914680.017
compound eye developmentGO:004874910.017
response to woundingGO:00096111680.016
positive regulation of purine nucleotide metabolic processGO:19005442270.016
metal ion transportGO:00300012720.016
defense response to fungusGO:005083240.016
cell substrate adhesionGO:00315891320.016
cell divisionGO:00513011680.016
negative regulation of cellular amine metabolic processGO:003323930.016
cell projection assemblyGO:00300311260.016
glycoprotein biosynthetic processGO:0009101910.016
regulation of bindingGO:00510981110.016
carbohydrate biosynthetic processGO:0016051420.016
lung alveolus developmentGO:004828640.016
innate immune responseGO:00450871780.016
negative regulation of apoptotic processGO:00430663160.016
regulation of erk1 and erk2 cascadeGO:0070372990.016
regulation of peptidyl tyrosine phosphorylationGO:00507301080.016
cell projection organizationGO:00300302520.016
positive regulation of transferase activityGO:00513472270.016
negative regulation of hydrolase activityGO:00513461820.015
protein catabolic processGO:00301633250.015
nitrogen compound transportGO:00717051910.015
regulation of sequence specific dna binding transcription factor activityGO:00510902110.015
regulation of protein localizationGO:00328802960.015
cation transportGO:00068123310.015
single organism cellular localizationGO:19025803320.015
regulation of protein serine threonine kinase activityGO:00719001790.015
regulation of body fluid levelsGO:0050878990.015
regulation of nucleotide metabolic processGO:00061402690.015
glycerophospholipid metabolic processGO:0006650840.015
negative regulation of programmed cell deathGO:00430693210.015
regulation of cell cycleGO:00517263930.015
cellular cation homeostasisGO:00300031630.015
guanosine containing compound catabolic processGO:19010692390.015
response to salt stressGO:000965130.015
carbohydrate catabolic processGO:0016052360.015
alcohol metabolic processGO:00060661140.015
cell activationGO:00017752130.015
neuromuscular junction developmentGO:000752830.015
purine ribonucleoside catabolic processGO:00461303980.015
positive regulation of nucleoside metabolic processGO:00459791860.014
chromatin organizationGO:00063253510.014
positive regulation of protein complex assemblyGO:0031334860.014
nucleoside catabolic processGO:00091644080.014
regulation of protein transportGO:00512232130.014
regulation of secretion by cellGO:19035301770.014
covalent chromatin modificationGO:00165692540.014
ribonucleoside catabolic processGO:00424544060.014
hormone secretionGO:0046879650.014
protein oligomerizationGO:00512591730.014
transmembrane transportGO:00550853990.014
negative regulation of organelle organizationGO:00106391260.014
positive regulation of kinase activityGO:00336742040.014
regulation of establishment of protein localizationGO:00702012420.014
response to fungusGO:000962040.014
negative regulation of cell differentiationGO:00455961710.014
protein dephosphorylationGO:0006470810.014
regulation of response to external stimulusGO:00321012220.014
regulation of nervous system developmentGO:0051960880.014
muscle system processGO:0003012810.014
response to extracellular stimulusGO:0009991850.014
cellular response to external stimulusGO:00714961110.014
monosaccharide metabolic processGO:0005996740.014
actin cytoskeleton organizationGO:00300362070.014
mitochondrion organizationGO:00070051560.014
cell cycle phase transitionGO:00447701730.014
cytoplasmic transportGO:00164823790.014
hexose metabolic processGO:0019318550.014
regulation of synaptic plasticityGO:004816730.013
regulation of secretionGO:00510461940.013
regulation of cellular component sizeGO:0032535820.013
regulation of vesicle mediated transportGO:00606271300.013
single organism cell adhesionGO:00986021790.013
organic acid biosynthetic processGO:0016053970.013
regulation of mapk cascadeGO:00434082620.013
positive regulation of cytokine productionGO:00018191670.013
negative regulation of cell proliferationGO:00082852280.013
chromatin modificationGO:00165682980.013
positive regulation of catabolic processGO:00098963100.013
small molecule biosynthetic processGO:00442831570.013
regulation of response to woundingGO:19030341010.013
regulation of cell activationGO:00508651250.013
cellular ion homeostasisGO:00068731680.013
hematopoietic or lymphoid organ developmentGO:00485341860.013
positive regulation of sequence specific dna binding transcription factor activityGO:00510911310.013
epithelium developmentGO:00604292270.013
positive regulation of protein kinase activityGO:00458601900.013
organelle fissionGO:00482851490.013
glucose metabolic processGO:0006006450.013
anatomical structure formation involved in morphogenesisGO:00486462840.013
proteolysis involved in cellular protein catabolic processGO:00516032440.013
viral processGO:00160321460.013
ion homeostasisGO:00508012300.013
neuroblast proliferationGO:000740540.013
oogenesisGO:004847720.013
maintenance of locationGO:00512351120.013
phospholipid biosynthetic processGO:0008654440.013
calcium ion transportGO:00068161470.013
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.013
regulation of multi organism processGO:00439001570.013
nucleoside triphosphate catabolic processGO:00091433940.012
single organism membrane organizationGO:00448022680.012
small molecule catabolic processGO:0044282920.012
divalent inorganic cation transportGO:00725111580.012
positive regulation of programmed cell deathGO:00430682490.012
amide transportGO:0042886760.012
rho protein signal transductionGO:0007266260.012
regulation of lipid metabolic processGO:0019216960.012
blood circulationGO:00080151130.012
regulation of cell developmentGO:00602841610.012
circulatory system processGO:00030131130.012
prostate gland morphogenesisGO:006051210.012
response to estradiolGO:0032355230.012
histone modificationGO:00165702510.012
peptide secretionGO:0002790510.012
regulation of actin filament based processGO:00329701410.012
cytokine mediated signaling pathwayGO:00192211090.012
Human Mouse
negative regulation of transferase activityGO:00513481240.012
blastoderm segmentationGO:000735020.012
single organism carbohydrate catabolic processGO:0044724330.012
response to cytokineGO:00340972320.012
Human Mouse
response to alcoholGO:0097305640.012
cellular homeostasisGO:00197251960.012
epithelial cell proliferationGO:00506731280.012
endosomal transportGO:00161971290.012
regulation of cytoskeleton organizationGO:00514931770.012
positive regulation of apoptotic processGO:00430652460.012
carboxylic acid biosynthetic processGO:0046394970.012
secretionGO:00469032540.012
cell cell signalingGO:00072671550.012
modification dependent macromolecule catabolic processGO:00436322120.012
spermatid differentiationGO:004851540.011
hemostasisGO:0007599760.011
regulation of protein maturationGO:19033171500.011
immune system developmentGO:00025201950.011
organelle assemblyGO:00709251760.011
regulation of protein processingGO:00706131500.011
macromolecule glycosylationGO:0043413630.011
positive regulation of gtp catabolic processGO:00331261660.011
microtubule based processGO:00070172100.011
endothelial cell migrationGO:0043542860.011
negative regulation of cell migrationGO:00303361020.011
oocyte developmentGO:004859910.011
gtp catabolic processGO:00061842370.011
positive regulation of mapk cascadeGO:00434101900.011
peptide transportGO:0015833740.011
negative regulation of cytoskeleton organizationGO:0051494450.011
ubiquitin dependent protein catabolic processGO:00065112060.011
negative regulation of cell cycleGO:00457861930.011
regulation of dna metabolic processGO:00510521530.011
behavioral response to ethanolGO:004814920.011
plasma membrane organizationGO:00070091150.011
protein maturationGO:00516042330.011
positive regulation of cell divisionGO:0051781590.011
memoryGO:000761330.011
hemopoiesisGO:00300971800.011
regulation of ras protein signal transductionGO:00465781550.011
blood coagulationGO:0007596760.011
regulation of cell divisionGO:00513021160.011
nucleotide catabolic processGO:00091664080.011
protein acetylationGO:00064731160.011
blood vessel morphogenesisGO:00485141620.011
regulation of cell adhesionGO:00301551660.011
negative regulation of intracellular signal transductionGO:19025321830.011
lipid localizationGO:00108761060.011
neurological system processGO:00508771630.011
angiogenesisGO:00015251470.011
response to radiationGO:00093141510.011
inorganic cation transmembrane transportGO:00986621940.011
negative regulation of phosphatidylinositol 3 kinase signalingGO:001406740.010
modification dependent protein catabolic processGO:00199412090.010
oocyte differentiationGO:000999420.010
positive regulation of cell deathGO:00109422630.010
fatty acid metabolic processGO:00066311150.010
protein processingGO:00164852260.010
regulation of small gtpase mediated signal transductionGO:00510561560.010
regulation of extrinsic apoptotic signaling pathwayGO:2001236850.010
positive regulation of secretion by cellGO:19035321080.010
metencephalon developmentGO:002203720.010
nucleoside phosphate biosynthetic processGO:19012931090.010
response to inorganic substanceGO:00100351270.010
glycerolipid biosynthetic processGO:0045017510.010
mitotic nuclear divisionGO:00070671190.010
peptide hormone secretionGO:0030072500.010
regulation of intracellular transportGO:00323861950.010
protein autophosphorylationGO:00467771230.010

SIGIRR disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:00146672950.029
inherited metabolic disorderDOID:6552420.029
disease of cellular proliferationDOID:145661740.023
cancerDOID:1621670.021
organ system cancerDOID:00506861640.020
nervous system diseaseDOID:8634310.015
sensory system diseaseDOID:00501552030.015
central nervous system diseaseDOID:3311860.014
musculoskeletal system diseaseDOID:172230.011
eye and adnexa diseaseDOID:14921500.011
eye diseaseDOID:56141490.011