Homo sapiens

20 known processes

SPC25

SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)

(Aliases: MGC22228,SPBC25,hSpc25)

SPC25 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
sister chromatid segregationGO:0000819540.503
regulation of cell cycleGO:00517263930.482
regulation of cell cycle processGO:00105642660.392
mitotic cell cycle processGO:19030472860.360
mitotic nuclear divisionGO:00070671190.320
nuclear divisionGO:00002801280.307
organelle fissionGO:00482851490.298
attachment of spindle microtubules to kinetochoreGO:0008608170.283
circulatory system developmentGO:00723592620.216
maintenance of location in cellGO:0051651620.208
post embryonic developmentGO:000979120.175
mitotic sister chromatid segregationGO:0000070530.160
protein catabolic processGO:00301633250.132
maintenance of protein locationGO:0045185570.128
nucleus localizationGO:005164710.127
regulation of proteolysisGO:00301622930.117
cellular macromolecule catabolic processGO:00442653800.117
single organism cellular localizationGO:19025803320.107
protein processingGO:00164852260.107
negative regulation of programmed cell deathGO:00430693210.101
nucleoside triphosphate metabolic processGO:00091414220.101
regulation of kinase activityGO:00435493140.098
negative regulation of cell cycleGO:00457861930.094
regulation of mitotic sister chromatid segregationGO:0033047270.091
regulation of mitosisGO:0007088630.089
regulation of protein catabolic processGO:00421761550.086
positive regulation of organelle organizationGO:00106381950.084
purine nucleoside catabolic processGO:00061523980.083
protein maturationGO:00516042330.079
ribonucleotide catabolic processGO:00092614050.077
nucleoside monophosphate catabolic processGO:00091251590.073
nucleoside triphosphate catabolic processGO:00091433940.072
negative regulation of mitotic metaphase anaphase transitionGO:0045841170.070
regulation of mitotic cell cycleGO:00073461890.067
organophosphate catabolic processGO:00464344300.067
regulation of meiotic cell cycleGO:005144540.065
regulation of cell cycle phase transitionGO:19019871260.063
microtubule anchoringGO:0034453240.063
positive regulation of catabolic processGO:00098963100.058
positive regulation of cell cycleGO:00457871400.057
nucleotide catabolic processGO:00091664080.057
protein localization to organelleGO:00333652800.054
ribonucleoside triphosphate catabolic processGO:00092033910.051
regulation of protein processingGO:00706131500.051
regulation of cellular component movementGO:00512703340.050
heart developmentGO:0007507950.050
cell cycle phase transitionGO:00447701730.049
cell divisionGO:00513011680.048
positive regulation of protein phosphorylationGO:00019343130.047
regulation of cell divisionGO:00513021160.046
chromosome segregationGO:00070591140.045
ribonucleoside catabolic processGO:00424544060.045
nucleoside phosphate catabolic processGO:19012924120.045
female gamete generationGO:000729220.045
nucleoside monophosphate metabolic processGO:00091231910.045
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434710.044
mitotic cell cycle phase transitionGO:00447721620.044
ribonucleoside triphosphate metabolic processGO:00091994120.042
protein localization to chromosome centromeric regionGO:0071459120.042
mitotic cell cycleGO:00002783260.041
microtubule cytoskeleton organizationGO:00002261760.040
negative regulation of mitotic cell cycleGO:00459301020.040
spindle assembly checkpointGO:0071173170.039
negative regulation of cell deathGO:00605483450.039
purine ribonucleoside triphosphate metabolic processGO:00092054110.039
ribonucleoside monophosphate catabolic processGO:00091581580.038
purine nucleoside triphosphate catabolic processGO:00091463920.038
proteasomal protein catabolic processGO:00104981760.037
mitotic sister chromatid separationGO:0051306180.037
attachment of mitotic spindle microtubules to kinetochoreGO:005131530.037
modification dependent protein catabolic processGO:00199412090.037
purine ribonucleoside metabolic processGO:00461284370.035
atp metabolic processGO:00460341760.034
peptidyl serine phosphorylationGO:00181051010.034
mitotic cell cycle checkpointGO:0007093680.034
negative regulation of cellular protein metabolic processGO:00322693530.033
regulation of protein kinase activityGO:00458592890.033
modification dependent macromolecule catabolic processGO:00436322120.033
vesicle mediated transportGO:00161923710.033
cell cycle checkpointGO:00000751170.033
regulation of transferase activityGO:00513383550.033
positive regulation of cell divisionGO:0051781590.032
purine nucleoside triphosphate metabolic processGO:00091444120.032
negative regulation of protein maturationGO:19033181420.032
regulation of cellular ketone metabolic processGO:0010565500.031
embryo developmentGO:00097901230.031
cellular protein complex assemblyGO:00436231880.031
regulation of protein localizationGO:00328802960.030
response to abiotic stimulusGO:00096283360.030
ribonucleoside monophosphate metabolic processGO:00091611870.030
maintenance of locationGO:00512351120.030
cellular ketone metabolic processGO:0042180800.030
apoptotic signaling pathwayGO:00971902680.029
negative regulation of protein metabolic processGO:00512483910.029
purine ribonucleoside triphosphate catabolic processGO:00092073910.028
regulation of cellular amine metabolic processGO:0033238110.028
nucleoside catabolic processGO:00091644080.028
tissue regenerationGO:004224630.028
intrinsic apoptotic signaling pathwayGO:00971931270.028
regulation of mitotic metaphase anaphase transitionGO:0030071260.027
negative regulation of cell cycle processGO:00109481210.027
positive regulation of mitosisGO:0045840250.027
positive regulation of hydrolase activityGO:00513453310.027
cardiovascular system developmentGO:00723582620.027
positive regulation of cellular catabolic processGO:00313312840.026
cell activationGO:00017752130.025
male meiosisGO:000714010.025
negative regulation of cell cycle phase transitionGO:1901988890.025
cellular amino acid metabolic processGO:00065201160.025
cellular protein catabolic processGO:00442572610.025
proteolysis involved in cellular protein catabolic processGO:00516032440.025
negative regulation of cellular component organizationGO:00511292350.024
purine ribonucleotide catabolic processGO:00091544040.024
regulation of mitotic cell cycle phase transitionGO:19019901180.024
positive regulation of programmed cell deathGO:00430682490.024
regulation of purine nucleotide metabolic processGO:19005422640.024
nervous system developmentGO:00073992930.024
response to oxygen containing compoundGO:19017003690.023
positive regulation of phosphorylationGO:00423273940.023
regulation of cell differentiationGO:00455953930.023
purine nucleoside monophosphate metabolic processGO:00091261860.023
purine nucleotide catabolic processGO:00061954050.022
purine ribonucleoside monophosphate metabolic processGO:00091671860.022
regulation of cellular amino acid metabolic processGO:000652160.022
single organism reproductive processGO:0044702980.022
meiotic chromosome segregationGO:004513240.022
negative regulation of mitotic cell cycle phase transitionGO:1901991850.021
negative regulation of catalytic activityGO:00430863350.021
posttranscriptional regulation of gene expressionGO:00106082130.021
reproductionGO:0000003630.020
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.020
atp catabolic processGO:00062001570.020
organelle localizationGO:0051640840.020
positive regulation of transferase activityGO:00513472270.020
organelle assemblyGO:00709251760.020
protein dna complex subunit organizationGO:0071824800.019
developmental process involved in reproductionGO:0003006660.019
establishment of cell polarityGO:0030010220.019
microtubule based processGO:00070172100.019
microtubule cytoskeleton organization involved in mitosisGO:1902850150.019
chromosome separationGO:0051304230.019
spindle organizationGO:0007051530.019
glycosyl compound catabolic processGO:19016584130.018
positive regulation of apoptotic processGO:00430652460.018
mitotic spindle assembly checkpointGO:0007094140.018
reproductive system developmentGO:0061458560.018
establishment of spindle orientationGO:005129490.018
cellular response to radiationGO:0071478650.018
regenerationGO:003109940.018
regulation of attachment of spindle microtubules to kinetochoreGO:005198890.018
purine ribonucleoside catabolic processGO:00461303980.018
purine containing compound catabolic processGO:00725234110.018
cellular macromolecular complex assemblyGO:00346223240.018
reproductive structure developmentGO:0048608550.018
regulation of protein maturationGO:19033171500.018
positive regulation of cell proliferationGO:00082843010.018
anatomical structure formation involved in morphogenesisGO:00486462840.018
positive regulation of protein kinase activityGO:00458601900.018
oogenesisGO:004847720.018
establishment of organelle localizationGO:0051656590.018
immune responseGO:00069553070.018
regulation of proteolysis involved in cellular protein catabolic processGO:1903050910.018
regulation of cell motilityGO:20001452990.017
cellular amine metabolic processGO:0044106410.017
multicellular organismal agingGO:001025930.017
nuclear migrationGO:000709710.017
blastocyst developmentGO:000182430.017
establishment of nucleus localizationGO:004002310.017
negative regulation of protein modification processGO:00314002000.017
cellular lipid metabolic processGO:00442553030.017
single organism membrane organizationGO:00448022680.016
dna repairGO:00062811980.016
negative regulation of phosphate metabolic processGO:00459362670.016
negative regulation of sister chromatid segregationGO:0033046170.016
positive regulation of cellular amino acid metabolic processGO:004576430.016
regulation of bindingGO:00510981110.016
reproductive processGO:00224141060.016
microtubule organizing center organizationGO:0031023620.016
ubiquitin dependent protein catabolic processGO:00065112060.016
cell developmentGO:00484683280.016
growthGO:00400072020.016
negative regulation of organelle organizationGO:00106391260.016
negative regulation of apoptotic processGO:00430663160.016
regulation of cellular component biogenesisGO:00440872810.015
regulation of chromosome segregationGO:0051983440.015
positive regulation of cellular component organizationGO:00511303760.015
regulation of proteasomal protein catabolic processGO:0061136870.015
negative regulation of protein processingGO:00109551420.015
regulation of endopeptidase activityGO:00525481700.015
positive regulation of cell deathGO:00109422630.015
leukocyte activationGO:00453211640.015
endocytosisGO:00068971590.014
protein oligomerizationGO:00512591730.014
regulation of locomotionGO:00400123290.014
regulation of mitotic sister chromatid separationGO:0010965270.014
negative regulation of cellular protein catabolic processGO:1903363380.014
negative regulation of catabolic processGO:00098951040.014
response to radiationGO:00093141510.014
protein depolymerizationGO:0051261300.014
cell fate determinationGO:000170930.014
cellular response to dna damage stimulusGO:00069743790.014
establishment of spindle localizationGO:0051293120.014
positive regulation of cell cycle processGO:00900681060.014
spermatid differentiationGO:004851540.014
cytokinesisGO:0000910960.013
positive regulation of kinase activityGO:00336742040.013
amine metabolic processGO:0009308440.013
negative regulation of intracellular signal transductionGO:19025321830.013
biological adhesionGO:00226103310.013
positive regulation of wnt signaling pathwayGO:0030177540.013
ras protein signal transductionGO:0007265730.013
regulation of cellular response to stressGO:00801352440.013
positive regulation of proteolysisGO:00458621420.012
purine ribonucleoside monophosphate catabolic processGO:00091691580.012
regulation of protein serine threonine kinase activityGO:00719001790.012
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic processGO:0031145250.012
negative regulation of cellular amine metabolic processGO:003323930.012
protein ubiquitinationGO:00165673140.012
negative regulation of phosphorylationGO:00423261740.012
neurogenesisGO:00220081690.012
metaphase plate congressionGO:0051310180.012
cell cell signalingGO:00072671550.012
histone modificationGO:00165702510.012
defense responseGO:00069523150.012
dna recombinationGO:0006310770.011
chromatin modificationGO:00165682980.011
enzyme linked receptor protein signaling pathwayGO:00071673030.011
negative regulation of phosphorus metabolic processGO:00105632670.011
positive regulation of purine nucleotide catabolic processGO:00331231850.011
determination of adult lifespanGO:000834020.011
intracellular protein transportGO:00068862700.011
regulation of apoptotic signaling pathwayGO:20012331750.011
neural crest cell migrationGO:000175520.011
regulation of wnt signaling pathwayGO:00301111230.011
regulation of purine nucleotide catabolic processGO:00331212050.011
regulation of cellular protein catabolic processGO:1903362960.011
wnt signaling pathwayGO:00160551560.011
cellular component morphogenesisGO:00329893140.011
reciprocal meiotic recombinationGO:000713140.011
regulation of nucleotide metabolic processGO:00061402690.011
regulation of chromosome organizationGO:00330441030.010
endomembrane system organizationGO:00102561960.010
centrosome separationGO:005129930.010
negative regulation of protein phosphorylationGO:00019331400.010
cytoplasmic transportGO:00164823790.010
positive regulation of mitotic sister chromatid separationGO:190197060.010
cellular homeostasisGO:00197251960.010

SPC25 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
physical disorderDOID:0080015410.050
congenital nervous system abnormalityDOID:2490210.050
disease of cellular proliferationDOID:145661740.033