Homo sapiens

82 known processes

PCM1

pericentriolar material 1

(Aliases: PTC4)

PCM1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cilium assemblyGO:0042384630.990
cilium morphogenesisGO:0060271750.941
organelle assemblyGO:00709251760.610
neural tube formationGO:000184130.608
embryonic epithelial tube formationGO:000183840.491
cellular component morphogenesisGO:00329893140.431
anatomical structure formation involved in morphogenesisGO:00486462840.387
positive regulation of organelle organizationGO:00106381950.386
eye photoreceptor cell differentiationGO:000175420.384
mitotic cell cycle processGO:19030472860.360
ubiquitin dependent protein catabolic processGO:00065112060.349
microtubule based processGO:00070172100.346
regulation of locomotionGO:00400123290.337
single organism cellular localizationGO:19025803320.335
microtubule cytoskeleton organizationGO:00002261760.329
morphogenesis of embryonic epitheliumGO:001633140.315
regulation of organelle assemblyGO:1902115400.309
cellular response to endogenous stimulusGO:00714953360.303
mitotic cell cycleGO:00002783260.298
cell morphogenesisGO:00009022960.296
post embryonic developmentGO:000979120.292
intraciliary transportGO:004207370.290
neuron differentiationGO:00301821380.264
microtubule based movementGO:0007018320.264
regulation of cell motilityGO:20001452990.256
intracellular protein transportGO:00068862700.244
neural tube closureGO:000184330.242
segmentationGO:003528240.238
circulatory system developmentGO:00723592620.233
generation of neuronsGO:00486991520.231
Mouse
modification dependent macromolecule catabolic processGO:00436322120.229
somitogenesisGO:000175620.224
neurological system processGO:00508771630.218
photoreceptor cell differentiationGO:004653020.214
maintenance of locationGO:00512351120.207
Mouse
regulation of cell cycleGO:00517263930.194
modification dependent protein catabolic processGO:00199412090.190
epithelium developmentGO:00604292270.187
cilium organizationGO:0044782680.186
cellular macromolecule catabolic processGO:00442653800.184
cell divisionGO:00513011680.173
heart developmentGO:0007507950.172
regulation of cell divisionGO:00513021160.170
protein localization to organelleGO:00333652800.169
Mouse
positive regulation of cellular component organizationGO:00511303760.169
protein localization to nucleusGO:00345041360.164
regulation of cellular component biogenesisGO:00440872810.163
cytokinesisGO:0000910960.162
regulation of cell cycle processGO:00105642660.159
regulation of cellular component movementGO:00512703340.158
cellular protein catabolic processGO:00442572610.156
protein localization to cytoskeletonGO:0044380110.155
Mouse
regulation of growthGO:00400081650.149
cell projection organizationGO:00300302520.144
photoreceptor cell maintenanceGO:0045494130.144
primary neural tube formationGO:001402030.142
growthGO:00400072020.141
regulation of cell morphogenesisGO:00226041530.141
cellular response to hormone stimulusGO:00328701250.137
cell projection assemblyGO:00300311260.136
cell projection morphogenesisGO:00488581290.134
cell developmentGO:00484683280.133
Mouse
protein catabolic processGO:00301633250.131
axis elongationGO:000340140.131
nucleoside triphosphate catabolic processGO:00091433940.128
convergent extension involved in gastrulationGO:006002710.128
tube closureGO:006060630.128
cellular response to cytokine stimulusGO:00713451810.127
sensory perceptionGO:00076001030.126
positive regulation of cellular component biogenesisGO:00440891580.123
response to cytokineGO:00340972320.119
response to hormoneGO:00097251750.119
protein localization to plasma membraneGO:0072659930.115
cellular response to dna damage stimulusGO:00069743790.112
glycosyl compound catabolic processGO:19016584130.110
microtubule anchoring at microtubule organizing centerGO:007239310.109
Mouse
sensory organ morphogenesisGO:0090596210.106
organelle localizationGO:0051640840.106
Mouse
epithelial tube morphogenesisGO:0060562380.104
cell part morphogenesisGO:00329901370.102
enzyme linked receptor protein signaling pathwayGO:00071673030.099
maintenance of location in cellGO:0051651620.094
Mouse
mrna metabolic processGO:00160711750.093
behaviorGO:00076101120.091
protein modification by small protein removalGO:0070646920.090
cytoplasmic transportGO:00164823790.090
proteolysis involved in cellular protein catabolic processGO:00516032440.089
regulation of microtubule based processGO:0032886740.088
negative regulation of developmental processGO:00510932470.087
Mouse
brain morphogenesisGO:004885410.085
limbic system developmentGO:002176130.085
purine ribonucleoside triphosphate catabolic processGO:00092073910.084
nucleoside catabolic processGO:00091644080.084
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.083
regulation of mitotic cell cycleGO:00073461890.082
cytokine mediated signaling pathwayGO:00192211090.081
maintenance of protein locationGO:0045185570.080
Mouse
response to growth factorGO:00708482050.079
spermatid differentiationGO:004851540.079
mitotic cell cycle phase transitionGO:00447721620.077
hippocampus developmentGO:002176610.076
system processGO:00030083490.074
positive regulation of cellular amine metabolic processGO:003324070.074
purine nucleoside triphosphate catabolic processGO:00091463920.072
positive regulation of programmed cell deathGO:00430682490.071
plasma membrane organizationGO:00070091150.071
morphogenesis of an epitheliumGO:0002009600.070
organ morphogenesisGO:00098871470.070
oogenesisGO:004847720.069
centrosome organizationGO:0051297580.067
tube morphogenesisGO:0035239950.067
purine ribonucleoside catabolic processGO:00461303980.067
nervous system developmentGO:00073992930.067
Mouse
cardiovascular system developmentGO:00723582620.067
positive regulation of protein transportGO:00512221350.066
protein localization to microtubule cytoskeletonGO:0072698100.065
Mouse
regulation of cell cycle phase transitionGO:19019871260.065
regulation of cilium movementGO:000335230.065
convergent extensionGO:006002610.064
nuclear transportGO:00511691790.064
negative regulation of systemic arterial blood pressureGO:000308510.063
purine nucleotide catabolic processGO:00061954050.063
neurogenesisGO:00220081690.062
Mouse
nucleoside phosphate catabolic processGO:19012924120.062
cellular component assembly involved in morphogenesisGO:0010927730.062
tissue homeostasisGO:0001894630.061
anatomical structure homeostasisGO:00602491000.061
regulation of cell projection organizationGO:00313441070.061
regulation of response to external stimulusGO:00321012220.059
neuron projection developmentGO:00311751060.059
multicellular organismal homeostasisGO:0048871670.059
ribonucleoside catabolic processGO:00424544060.058
cellular macromolecular complex assemblyGO:00346223240.058
nucleoside triphosphate metabolic processGO:00091414220.057
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781250.057
regulation of dna metabolic processGO:00510521530.055
regulation of cytoskeleton organizationGO:00514931770.055
positive regulation of developmental processGO:00510943140.054
female gamete generationGO:000729220.054
cell cycle phase transitionGO:00447701730.054
locomotory behaviorGO:000762610.053
purine nucleoside catabolic processGO:00061523980.053
spermatid developmentGO:000728640.053
purine ribonucleotide catabolic processGO:00091544040.053
proteasomal protein catabolic processGO:00104981760.051
regulation of anatomical structure morphogenesisGO:00226032860.051
dendrite developmentGO:0016358240.051
establishment of organelle localizationGO:0051656590.049
cellular amine metabolic processGO:0044106410.049
positive regulation of nucleotide catabolic processGO:00308131850.048
cellular amino acid metabolic processGO:00065201160.048
regulation of cellular amine metabolic processGO:0033238110.048
protein localization to membraneGO:00726571600.048
determination of adult lifespanGO:000834020.047
protein deubiquitinationGO:0016579790.047
lipid metabolic processGO:00066293810.046
purine containing compound catabolic processGO:00725234110.046
embryonic morphogenesisGO:0048598850.046
ribonucleoside triphosphate metabolic processGO:00091994120.046
protein localization to centrosomeGO:007153950.046
Mouse
eye developmentGO:0001654420.046
membrane organizationGO:00610242920.045
cellular response to growth factor stimulusGO:00713631970.045
neuron developmentGO:00486661130.045
dna repairGO:00062811980.045
regulation of intracellular transportGO:00323861950.044
nucleotide catabolic processGO:00091664080.044
response to abiotic stimulusGO:00096283360.044
mitotic cytokinesisGO:0000281190.043
digestive tract developmentGO:0048565750.043
digestive tract morphogenesisGO:0048546560.042
multicellular organismal agingGO:001025930.041
forebrain developmentGO:0030900260.040
Mouse
epithelial tube formationGO:007217550.040
positive regulation of cell projection organizationGO:0031346640.039
head developmentGO:00603221080.039
Mouse
positive regulation of transportGO:00510503360.039
purine nucleoside triphosphate metabolic processGO:00091444120.039
ribonucleotide catabolic processGO:00092614050.038
protein processingGO:00164852260.037
maintenance of protein location in cellGO:0032507560.036
Mouse
purine ribonucleoside metabolic processGO:00461284370.036
single organism membrane organizationGO:00448022680.036
spindle organizationGO:0007051530.036
negative regulation of catalytic activityGO:00430863350.035
developmental growth involved in morphogenesisGO:0060560230.035
single organism reproductive processGO:0044702980.035
establishment of protein localization to organelleGO:00725941720.034
positive regulation of intracellular protein transportGO:0090316760.034
protein maturationGO:00516042330.034
regulation of lipid metabolic processGO:0019216960.034
negative regulation of response to external stimulusGO:0032102830.034
negative regulation of cell cycleGO:00457861930.034
chromatin modificationGO:00165682980.033
embryo development ending in birth or egg hatchingGO:0009792340.033
determination of bilateral symmetryGO:0009855150.033
tissue morphogenesisGO:0048729960.033
negative regulation of apoptotic processGO:00430663160.032
positive regulation of organelle assemblyGO:1902117170.032
positive regulation of hydrolase activityGO:00513453310.032
regulation of nucleotide metabolic processGO:00061402690.031
sensory perception of smellGO:000760820.031
positive regulation of cell divisionGO:0051781590.031
translationGO:00064121320.031
telencephalon developmentGO:0021537170.031
positive regulation of cell cycleGO:00457871400.031
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.031
positive regulation of apoptotic processGO:00430652460.030
regulation of cellular amino acid metabolic processGO:000652160.030
epithelial cell differentiationGO:00308551410.029
nucleoside monophosphate catabolic processGO:00091251590.029
determination of left right symmetryGO:0007368110.029
notch signaling pathwayGO:0007219310.029
circulatory system processGO:00030131130.029
negative regulation of phosphate metabolic processGO:00459362670.029
negative regulation of proteolysisGO:00458611320.029
response to radiationGO:00093141510.029
regulation of gtp catabolic processGO:00331241800.029
digestive system developmentGO:0055123750.029
single organism nuclear importGO:19025931040.028
cellular ketone metabolic processGO:0042180800.028
rna processingGO:00063962550.028
positive regulation of nucleotide metabolic processGO:00459812300.028
pallium developmentGO:0021543100.028
developmental process involved in reproductionGO:0003006660.028
neuromuscular junction developmentGO:000752830.028
retina homeostasisGO:0001895420.027
spindle assemblyGO:0051225290.027
hindbrain developmentGO:003090230.027
negative regulation of cell proliferationGO:00082852280.027
apoptotic signaling pathwayGO:00971902680.027
nucleocytoplasmic transportGO:00069131760.027
positive regulation of catabolic processGO:00098963100.027
subpallium developmentGO:002154420.027
purine ribonucleoside triphosphate metabolic processGO:00092054110.027
pigmentationGO:0043473220.027
establishment of protein localization to membraneGO:00901501210.027
cilium movementGO:000334190.027
ribonucleoside triphosphate catabolic processGO:00092033910.026
positive regulation of cell proliferationGO:00082843010.026
negative regulation of hydrolase activityGO:00513461820.026
negative regulation of programmed cell deathGO:00430693210.026
embryonic organ developmentGO:0048568360.025
negative regulation of phosphorus metabolic processGO:00105632670.025
posttranscriptional regulation of gene expressionGO:00106082130.025
regulation of mitotic cell cycle phase transitionGO:19019901180.025
response to extracellular stimulusGO:0009991850.025
vesicle mediated transportGO:00161923710.024
metencephalon developmentGO:002203720.024
positive regulation of cell cycle processGO:00900681060.024
neural tube developmentGO:002191590.024
fat cell differentiationGO:0045444320.024
adult behaviorGO:0030534180.024
maintenance of protein location in nucleusGO:0051457120.024
positive regulation of cell deathGO:00109422630.024
heart morphogenesisGO:0003007480.024
protein import into nucleusGO:00066061040.024
amine metabolic processGO:0009308440.023
organelle fissionGO:00482851490.023
negative regulation of mitotic cell cycleGO:00459301020.023
regulation of appetiteGO:003209810.023
eye pigmentationGO:004806910.023
somite developmentGO:006105370.023
sensory organ developmentGO:0007423520.023
regulation of protein localizationGO:00328802960.023
oocyte developmentGO:004859910.022
positive regulation of cellular amino acid metabolic processGO:004576430.022
axis elongation involved in somitogenesisGO:009024510.022
organophosphate catabolic processGO:00464344300.022
regulation of cell migrationGO:00303342890.022
gastrulationGO:0007369510.022
purine nucleoside monophosphate metabolic processGO:00091261860.021
chromosome segregationGO:00070591140.021
negative regulation of multicellular organismal processGO:00512413170.021
Mouse
positive regulation of phosphorylationGO:00423273940.021
matingGO:000761810.021
regulation of meiotic cell cycleGO:005144540.021
negative regulation of cell differentiationGO:00455961710.021
Mouse
cilium or flagellum dependent cell motilityGO:000153940.021
nuclear importGO:00511701060.020
gtp catabolic processGO:00061842370.020
positive regulation of gtp catabolic processGO:00331261660.020
mitotic sister chromatid separationGO:0051306180.020
small gtpase mediated signal transductionGO:0007264780.020
response to bacteriumGO:00096171440.020
cerebral cortex developmentGO:0021987100.020
guanosine containing compound metabolic processGO:19010682440.020
cellular response to oxygen containing compoundGO:19017012760.020
regulation of intracellular protein transportGO:00331571230.020
negative regulation of cell cycle processGO:00109481210.020
regulation of cytokinesisGO:0032465450.020
endomembrane system organizationGO:00102561960.020
positive regulation of cellular catabolic processGO:00313312840.020
regulation of epithelial cell proliferationGO:00506781130.019
chemotaxisGO:00069351570.019
blood circulationGO:00080151130.019
brain developmentGO:0007420970.019
Mouse
regulation of purine nucleotide metabolic processGO:19005422640.019
chordate embryonic developmentGO:0043009340.019
regulation of gtpase activityGO:00430871800.019
epithelial cell proliferationGO:00506731280.019
chromatin organizationGO:00063253510.019
positive regulation of intracellular transportGO:00323881040.019
cerebellum developmentGO:002154920.019
embryo developmentGO:00097901230.019
striatum developmentGO:002175620.019
cellular response to nitrogen compoundGO:19016991440.019
transforming growth factor beta receptor signaling pathwayGO:0007179760.019
regulation of protein complex assemblyGO:00432541470.018
protein targeting to nucleusGO:00447441040.018
negative regulation of catabolic processGO:00098951040.018
negative regulation of growthGO:0045926970.018
regulation of proteolysisGO:00301622930.018
negative regulation of cell cycle phase transitionGO:1901988890.018
reproductive processGO:00224141060.018
embryonic organ morphogenesisGO:0048562240.018
regionalizationGO:0003002290.018
dna recombinationGO:0006310770.017
regulation of ras gtpase activityGO:00323181280.017
response to oxygen containing compoundGO:19017003690.017
response to nutrient levelsGO:0031667810.017
mitotic nuclear divisionGO:00070671190.017
epithelial cell migrationGO:00106311190.017
response to foodGO:003209410.017
regulation of protein maturationGO:19033171500.016
negative regulation of protein metabolic processGO:00512483910.016
positive regulation of cell motilityGO:20001471770.016
cilium dependent cell motilityGO:006028540.016
cytoskeleton dependent intracellular transportGO:0030705210.016
mrna splicing via spliceosomeGO:0000398890.016
regulation of cellular response to stressGO:00801352440.016
protein targetingGO:00066051870.016
positive regulation of purine nucleotide metabolic processGO:19005442270.016
regulation of sequence specific dna binding transcription factor activityGO:00510902110.016
rab protein signal transductionGO:003248240.016
negative regulation of cellular protein metabolic processGO:00322693530.016
positive regulation of mitosisGO:0045840250.016
adult locomotory behaviorGO:000834410.015
multicellular organismal reproductive processGO:0048609400.015
stem cell differentiationGO:0048863930.015
Mouse
positive regulation of ras gtpase activityGO:00323201170.015
methylationGO:00322591060.015
regulation of cell projection assemblyGO:0060491470.015
dephosphorylationGO:00163112090.015
developmental growthGO:0048589480.015
rna splicingGO:00083801310.015
negative regulation of response to extracellular stimulusGO:003210550.015
regulation of microtubule cytoskeleton organizationGO:0070507610.015
positive regulation of gtpase activityGO:00435471660.015
negative regulation of apoptotic signaling pathwayGO:2001234970.015
purine ribonucleoside monophosphate catabolic processGO:00091691580.015
regulation of chromosome organizationGO:00330441030.015
developmental programmed cell deathGO:001062330.015
ribonucleoprotein complex assemblyGO:0022618780.015
single organism behaviorGO:0044708280.015
taxisGO:00423301570.015
regulation of cell differentiationGO:00455953930.014
Mouse
dna replicationGO:00062601160.014
muscle structure developmentGO:0061061980.014
regulation of apoptotic signaling pathwayGO:20012331750.014
endothelial cell migrationGO:0043542860.014
memoryGO:000761330.014
actin filament based processGO:00300292240.014
regulation of protein targetingGO:1903533910.014
regulation of cytoplasmic transportGO:19036491490.014
cell adhesionGO:00071553250.014
negative regulation of phosphatase activityGO:0010923610.014
negative regulation of cell deathGO:00605483450.014
negative regulation of epithelial cell proliferationGO:0050680480.014
tube formationGO:0035148100.014
protein importGO:00170381300.014
nucleoside monophosphate metabolic processGO:00091231910.014
mitotic sister chromatid segregationGO:0000070530.014
positive regulation of nucleoside metabolic processGO:00459791860.013
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.013
mrna processingGO:00063971330.013
eye morphogenesisGO:0048592160.013
positive regulation of purine nucleotide catabolic processGO:00331231850.013
biological adhesionGO:00226103310.013
immune system developmentGO:00025201950.013
cellular response to external stimulusGO:00714961110.013
vasculature developmentGO:00019441810.013
response to biotic stimulusGO:00096072760.013
central nervous system developmentGO:00074171230.013
Mouse
regulation of developmental growthGO:0048638300.013
positive regulation of immune system processGO:00026842830.013
histone modificationGO:00165702510.013
regulation of cysteine type endopeptidase activityGO:20001161270.013
pigment granule localizationGO:005187570.013
regulation of response to nutrient levelsGO:0032107220.013
ribonucleoprotein complex subunit organizationGO:0071826810.013
positive regulation of rab gtpase activityGO:0032851390.013
oocyte differentiationGO:000999420.013
response to ionizing radiationGO:0010212650.013
innate immune responseGO:00450871780.012
regulation of nuclear divisionGO:0051783650.012
regulation of cellular ketone metabolic processGO:0010565500.012
pigment metabolic processGO:0042440160.012
maintenance of protein localization in organelleGO:0072595150.012
regulation of protein processingGO:00706131500.012
regulation of immune responseGO:00507762010.012
purine nucleoside monophosphate catabolic processGO:00091281580.012
positive regulation of cytoplasmic transportGO:1903651820.012
regulation of multicellular organism growthGO:004001480.012
chromosome separationGO:0051304230.012
mapk cascadeGO:00001652880.012
establishment of protein localization to plasma membraneGO:0090002680.012
sister chromatid segregationGO:0000819540.012
developmental pigmentationGO:0048066120.012
positive regulation of growthGO:0045927580.012
g2 m transition of mitotic cell cycleGO:0000086410.012
angiogenesisGO:00015251470.012
double strand break repairGO:00063021010.012
guanosine containing compound catabolic processGO:19010692390.012
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377890.012
purine ribonucleoside monophosphate metabolic processGO:00091671860.012
regulation of ras protein signal transductionGO:00465781550.012
cellular homeostasisGO:00197251960.012
er associated ubiquitin dependent protein catabolic processGO:0030433310.012
regulation of cilium assemblyGO:190201760.012
regulation of stem cell differentiationGO:2000736560.011
secretion by cellGO:00329402260.011
regulation of nucleocytoplasmic transportGO:0046822980.011
rna interferenceGO:001624640.011
blastoderm segmentationGO:000735020.011
positive regulation of mitotic cell cycleGO:0045931600.011
positive regulation of cellular component movementGO:00512721810.011
neuroblast proliferationGO:000740540.011
regulation of neurogenesisGO:0050767820.011
Mouse
nucleic acid phosphodiester bond hydrolysisGO:00903051020.011
cellular response to insulin stimulusGO:0032869410.011
regulation of rab protein signal transductionGO:0032483390.011
endocytosisGO:00068971590.011
immune responseGO:00069553070.011
regulation of protein catabolic processGO:00421761550.011
spindle elongationGO:005123140.011
melanosome transportGO:003240250.011
cell morphogenesis involved in differentiationGO:00009041440.011
negative regulation of protein processingGO:00109551420.011
metaphase anaphase transition of cell cycleGO:0044784210.011
cellular protein complex assemblyGO:00436231880.011
ribonucleoprotein complex biogenesisGO:00226131160.011
nonmotile primary cilium assemblyGO:003505840.011
actin cytoskeleton organizationGO:00300362070.011
meiosis iGO:000712740.011
cell cycle checkpointGO:00000751170.011
positive regulation of locomotionGO:00400171860.011
regulation of protein transportGO:00512232130.011
cellular response to organonitrogen compoundGO:00714171240.011
reproductionGO:0000003630.010
regulation of wnt signaling pathwayGO:00301111230.010
response to organic cyclic compoundGO:00140702040.010
positive regulation of cell migrationGO:00303351720.010
gtp metabolic processGO:00460392390.010
dna geometric changeGO:0032392320.010
regulation of actin cytoskeleton organizationGO:00329561160.010
negative regulation of extracellular matrix disassemblyGO:001071630.010
mitotic spindle elongationGO:000002240.010
reproductive structure developmentGO:0048608550.010
regulation of gene expression epigeneticGO:0040029730.010

PCM1 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:8634310.030
sensory system diseaseDOID:00501552030.030
eye and adnexa diseaseDOID:14921500.024
eye diseaseDOID:56141490.021
disease of cellular proliferationDOID:145661740.019
joubert syndromeDOID:0050777180.017
neurodegenerative diseaseDOID:12891020.011
central nervous system diseaseDOID:3311860.011
cancerDOID:1621670.008
organ system cancerDOID:00506861640.007
endocrine gland cancerDOID:170260.002
thyroid cancerDOID:1781130.001
thyroid carcinomaDOID:3963130.001
papillary thyroid carcinomaDOID:396960.001