Homo sapiens

491 known processes

LRRK2

leucine-rich repeat kinase 2

(Aliases: ROCO2,DARDARIN,PARK8,RIPK7,AURA17)

LRRK2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of neurotransmitter secretionGO:004692830.999
neurotransmitter secretionGO:000726940.999
canonical wnt signaling pathway involved in heart developmentGO:006131630.999
regulation of synaptic vesicle exocytosisGO:200030020.997
positive regulation of protein kinase activityGO:00458601900.995
positive regulation of cellular component organizationGO:00511303760.990
neural tube formationGO:000184130.988
negative regulation of non canonical wnt signaling pathwayGO:200005110.987
positive regulation of mapk cascadeGO:00434101900.986
positive regulation of map kinase activityGO:0043406800.982
positive regulation of phosphorylationGO:00423273940.981
regulation of protein serine threonine kinase activityGO:00719001790.981
embryonic epithelial tube formationGO:000183840.971
cellular component morphogenesisGO:00329893140.969
regulation of mapk cascadeGO:00434082620.968
positive regulation of transferase activityGO:00513472270.966
establishment or maintenance of apical basal cell polarityGO:003508820.958
regulation of intracellular transportGO:00323861950.957
cell developmentGO:00484683280.957
establishment of vesicle localizationGO:0051650230.956
regulation of heart inductionGO:009038120.951
outflow tract septum morphogenesisGO:000314840.949
positive regulation of protein serine threonine kinase activityGO:00719021190.948
purine ribonucleoside catabolic processGO:00461303980.943
wnt signaling pathway planar cell polarity pathwayGO:006007150.941
purine ribonucleoside metabolic processGO:00461284370.941
cell cell signalingGO:00072671550.940
positive regulation of cytoplasmic transportGO:1903651820.937
microtubule cytoskeleton organizationGO:00002261760.931
Fly
positive regulation of transportGO:00510503360.924
regulation of cell projection organizationGO:00313441070.923
purine ribonucleoside triphosphate catabolic processGO:00092073910.915
positive regulation of catabolic processGO:00098963100.913
blood circulationGO:00080151130.911
positive regulation of apoptotic processGO:00430652460.910
regulation of protein kinase activityGO:00458592890.907
mapk cascadeGO:00001652880.904
non canonical wnt signaling pathway via mapk cascadeGO:003803040.900
establishment or maintenance of monopolar cell polarityGO:006133910.900
synaptic vesicle endocytosisGO:004848820.900
Fly
lipid transportGO:0006869900.895
positive regulation of protein phosphorylationGO:00019343130.893
positive regulation of kinase activityGO:00336742040.886
synaptic vesicle exocytosisGO:001607930.886
purine containing compound catabolic processGO:00725234110.882
nucleoside triphosphate metabolic processGO:00091414220.882
wnt signaling pathway involved in heart developmentGO:000330650.877
protein polymerizationGO:0051258710.873
single organism membrane organizationGO:00448022680.871
synaptic vesicle localizationGO:009747950.871
guanosine containing compound metabolic processGO:19010682440.871
regulation of ion transportGO:00432691890.870
membrane organizationGO:00610242920.865
regulation of kinase activityGO:00435493140.863
activation of protein kinase activityGO:0032147900.856
primary neural tube formationGO:001402030.849
establishment of monopolar cell polarityGO:006116210.847
regulation of cellular ketone metabolic processGO:0010565500.846
nucleotide catabolic processGO:00091664080.845
regulation of cellular component biogenesisGO:00440872810.843
positive regulation of cell deathGO:00109422630.841
establishment or maintenance of bipolar cell polarityGO:006124520.841
heart inductionGO:000312940.841
striated muscle contractionGO:0006941520.825
regulation of cellular amine metabolic processGO:0033238110.824
positive regulation of cellular amine metabolic processGO:003324070.821
heart formationGO:006091420.819
nucleoside phosphate catabolic processGO:19012924120.802
anatomical structure formation involved in morphogenesisGO:00486462840.801
neuron differentiationGO:00301821380.797
tube closureGO:006060630.796
regulation of neurotransmitter levelsGO:0001505150.794
positive regulation of intracellular transportGO:00323881040.788
specification of organ identityGO:001009230.787
protein localization to organelleGO:00333652800.785
system processGO:00030083490.779
regulation of jnk cascadeGO:0046328730.778
positive regulation of cellular amino acid metabolic processGO:004576430.777
regulation of map kinase activityGO:00434051080.771
regulation of neurotransmitter transportGO:005158870.768
establishment of organelle localizationGO:0051656590.768
developmental cell growthGO:0048588180.768
Worm
purine nucleoside triphosphate catabolic processGO:00091463920.763
nucleoside catabolic processGO:00091644080.760
regulation of heart morphogenesisGO:200082640.760
regulation of microtubule based processGO:0032886740.759
Fly
establishment of tissue polarityGO:000716430.751
cellular response to oxygen containing compoundGO:19017012760.749
positive regulation of immune responseGO:00507781590.748
regulation of transferase activityGO:00513383550.747
regulation of cytoskeleton organizationGO:00514931770.745
Fly
sterol transportGO:0015918390.741
actin filament organizationGO:00070151280.731
single organism cellular localizationGO:19025803320.731
non canonical wnt signaling pathwayGO:0035567140.719
positive regulation of developmental processGO:00510943140.718
anion transportGO:00068201610.718
morphogenesis of a polarized epitheliumGO:000173830.716
negative regulation of heart induction by canonical wnt signaling pathwayGO:000313610.710
secretionGO:00469032540.707
positive regulation of programmed cell deathGO:00430682490.706
vacuole organizationGO:0007033440.698
regulation of cellular amino acid metabolic processGO:000652160.696
ribonucleoside triphosphate metabolic processGO:00091994120.694
circulatory system processGO:00030131130.691
ribonucleoside triphosphate catabolic processGO:00092033910.687
cellular response to abiotic stimulusGO:00712141170.687
negative regulation of apoptotic processGO:00430663160.681
stress activated protein kinase signaling cascadeGO:0031098940.677
wnt signaling pathwayGO:00160551560.676
response to salt stressGO:000965130.672
organelle inheritanceGO:004830820.672
purine nucleoside catabolic processGO:00061523980.671
nervous system developmentGO:00073992930.664
amine metabolic processGO:0009308440.664
positive regulation of jun kinase activityGO:0043507230.660
regulation of protein polymerizationGO:0032271630.658
actin filament based processGO:00300292240.651
ribonucleotide catabolic processGO:00092614050.651
establishment of planar polarityGO:000173630.650
retina vasculature morphogenesis in camera type eyeGO:006129930.648
synaptic transmissionGO:0007268610.647
growthGO:00400072020.643
Worm
positive regulation of protein tyrosine kinase activityGO:0061098240.639
peptidyl serine phosphorylationGO:00181051010.635
neuroblast divisionGO:005505710.631
carbohydrate metabolic processGO:00059752070.627
canonical wnt signaling pathwayGO:00600701160.616
regulation of mitosisGO:0007088630.607
response to reactive oxygen speciesGO:0000302610.606
negative regulation of catalytic activityGO:00430863350.604
regulation of stress activated mapk cascadeGO:0032872840.603
morphogenesis of a branching structureGO:0001763210.595
regulation of cellular response to stressGO:00801352440.593
cardioblast cell fate commitmentGO:004268410.588
cellular protein complex assemblyGO:00436231880.586
negative regulation of cardiac muscle tissue developmentGO:005502670.586
cellular ketone metabolic processGO:0042180800.577
organophosphate catabolic processGO:00464344300.576
mammary gland formationGO:006059210.574
activation of innate immune responseGO:0002218550.566
synaptic vesicle recyclingGO:003646530.561
Fly
dendrite developmentGO:0016358240.560
regulation of microtubule cytoskeleton organizationGO:0070507610.559
Fly
signal transduction by phosphorylationGO:00230142970.557
regulation of fatty acid transportGO:200019180.555
negative regulation of phosphate metabolic processGO:00459362670.551
activation of mapk activityGO:0000187450.546
heart field specificationGO:000312820.534
organic hydroxy compound transportGO:0015850630.526
regulation of carbohydrate metabolic processGO:0006109540.524
positive regulation of stress activated mapk cascadeGO:0032874600.523
regulation of cellular component sizeGO:0032535820.518
neural tube closureGO:000184330.517
endomembrane system organizationGO:00102561960.513
regulation of nucleoside metabolic processGO:00091182090.512
ion transmembrane transportGO:00342203380.511
regulation of proteolysisGO:00301622930.508
Mouse
response to abiotic stimulusGO:00096283360.506
positive regulation of cellular catabolic processGO:00313312840.502
regulation of organ formationGO:000315640.499
organelle fissionGO:00482851490.492
negative regulation of protein modification processGO:00314002000.489
Mouse
peptidyl threonine modificationGO:0018210450.478
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.477
immune response activating signal transductionGO:0002757900.477
regulation of protein targetingGO:1903533910.477
neurotransmitter transportGO:0006836100.476
regulation of anion transportGO:0044070250.473
activation of immune responseGO:00022531140.473
negative regulation of cellular protein metabolic processGO:00322693530.471
Mouse
organelle localizationGO:0051640840.470
exocytosisGO:0006887710.467
regulation of protein localizationGO:00328802960.466
positive regulation of axon extensionGO:004577340.462
retinal ganglion cell axon guidanceGO:003129020.459
negative regulation of cell fate commitmentGO:001045430.459
establishment or maintenance of epithelial cell apical basal polarityGO:004519710.459
positive regulation of defense responseGO:0031349870.456
vesicle localizationGO:0051648260.455
developmental growth involved in morphogenesisGO:0060560230.454
Worm
gtp catabolic processGO:00061842370.452
cellular calcium ion homeostasisGO:00068741170.447
apoptotic signaling pathwayGO:00971902680.447
establishment of protein localization to organelleGO:00725941720.446
non canonical wnt signaling pathway via jnk cascadeGO:003803130.445
negative regulation of cardioblast differentiationGO:005189220.438
regulation of establishment of planar polarityGO:009017550.437
purine ribonucleotide catabolic processGO:00091544040.435
regulation of nucleotide metabolic processGO:00061402690.435
cell morphogenesisGO:00009022960.434
cell projection organizationGO:00300302520.434
epidermis morphogenesisGO:004873030.431
modification dependent protein catabolic processGO:00199412090.430
Mouse
negative chemotaxisGO:0050919110.430
heart processGO:0003015620.429
postsynaptic membrane organizationGO:000194120.428
morphogenesis of embryonic epitheliumGO:001633140.426
cell type specific apoptotic processGO:00972851250.424
response to oxygen containing compoundGO:19017003690.423
establishment of apical basal cell polarityGO:003508910.423
cellular divalent inorganic cation homeostasisGO:00725031280.420
negative regulation of synaptic transmissionGO:005080520.420
receptor internalizationGO:0031623430.419
convergent extensionGO:006002610.413
heart contractionGO:0060047620.409
purine nucleoside triphosphate metabolic processGO:00091444120.408
cellular amino acid metabolic processGO:00065201160.408
single organism carbohydrate metabolic processGO:00447231930.406
transmembrane transportGO:00550853990.404
hindlimb morphogenesisGO:003513720.403
neuromuscular junction developmentGO:000752830.403
positive regulation of jnk cascadeGO:0046330520.397
regulation of anatomical structure sizeGO:00900661010.394
Mouse
regulation of secretion by cellGO:19035301770.391
g protein coupled receptor signaling pathwayGO:00071862070.388
peptidyl tyrosine modificationGO:00182121700.388
regulation of mitotic cell cycleGO:00073461890.383
vesicle mediated transportGO:00161923710.382
epithelium developmentGO:00604292270.381
cytoplasmic transportGO:00164823790.380
post embryonic developmentGO:000979120.376
canonical wnt signaling pathway involved in regulation of cell proliferationGO:004434020.376
glycosyl compound catabolic processGO:19016584130.375
negative regulation of cardioblast cell fate specificationGO:000999710.375
intracellular protein transportGO:00068862700.373
regulation of cytoplasmic transportGO:19036491490.363
negative regulation of programmed cell deathGO:00430693210.363
muscle system processGO:0003012810.354
cell projection morphogenesisGO:00488581290.348
positive regulation of cell differentiationGO:00455972110.348
tube morphogenesisGO:0035239950.347
positive regulation of organelle organizationGO:00106381950.347
regulation of sequence specific dna binding transcription factor activityGO:00510902110.343
regulation of calcium ion transportGO:0051924790.342
locomotory behaviorGO:000762610.337
Mouse
regulation of synaptic vesicle transportGO:190280330.333
ubiquitin dependent protein catabolic processGO:00065112060.332
Mouse
regulation of cardioblast cell fate specificationGO:004268610.330
lipid localizationGO:00108761060.327
jnk cascadeGO:0007254800.327
cardiac muscle contractionGO:0060048340.324
regulation of excitatory postsynaptic membrane potentialGO:006007910.321
Mouse
negative regulation of protein kinase activityGO:0006469980.317
positive regulation of gtp catabolic processGO:00331261660.316
embryonic forelimb morphogenesisGO:003511540.314
small gtpase mediated signal transductionGO:0007264780.313
peptidyl tyrosine phosphorylationGO:00181081700.311
regulation of immune responseGO:00507762010.309
cell divisionGO:00513011680.309
generation of neuronsGO:00486991520.309
myoblast fusionGO:000752010.306
regulation of actin cytoskeleton organizationGO:00329561160.305
purine ribonucleoside triphosphate metabolic processGO:00092054110.304
positive regulation of cell projection organizationGO:0031346640.303
collateral sproutingGO:004866820.298
positive regulation of cellular protein catabolic processGO:1903364370.297
Mouse
regulation of protein transportGO:00512232130.297
organ morphogenesisGO:00098871470.296
Mouse
positive regulation of organic acid transportGO:003289230.295
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434710.295
Mouse
developmental growthGO:0048589480.293
Worm
response to cytokineGO:00340972320.292
neuron projection extensionGO:1990138140.291
Worm
guanosine containing compound catabolic processGO:19010692390.291
negative regulation of cell deathGO:00605483450.291
positive regulation of protein polymerizationGO:0032273450.290
negative regulation of hydrolase activityGO:00513461820.288
purine nucleotide catabolic processGO:00061954050.285
cellular response to metal ionGO:0071248430.283
stem cell divisionGO:001714520.278
cellular amine metabolic processGO:0044106410.277
establishment or maintenance of cell polarityGO:0007163310.276
carboxylic acid transportGO:0046942630.276
vesicle organizationGO:0016050620.274
mitotic cell cycleGO:00002783260.274
cellular macromolecule catabolic processGO:00442653800.272
Mouse
positive regulation of hydrolase activityGO:00513453310.270
ribonucleoside catabolic processGO:00424544060.269
reproductive processGO:00224141060.268
regulation of cardioblast differentiationGO:005189040.267
divalent inorganic cation transportGO:00725111580.262
oogenesisGO:004847720.261
forelimb morphogenesisGO:003513640.260
neuronal stem cell divisionGO:003644510.260
positive regulation of peptidyl serine phosphorylationGO:0033138420.260
cell morphogenesis involved in differentiationGO:00009041440.259
protein catabolic processGO:00301633250.257
Mouse
long term memoryGO:000761620.255
proteolysis involved in cellular protein catabolic processGO:00516032440.255
Mouse
neuron projection developmentGO:00311751060.254
regulation of innate immune responseGO:0045088970.253
positive regulation of canonical wnt signaling pathwayGO:0090263330.252
negative regulation of protein processingGO:00109551420.252
stress activated mapk cascadeGO:0051403930.251
axis elongationGO:000340140.249
memoryGO:000761330.249
protein localization to nucleusGO:00345041360.249
epithelial tube morphogenesisGO:0060562380.247
positive regulation of nucleotide metabolic processGO:00459812300.246
negative regulation of protein phosphorylationGO:00019331400.244
Mouse
negative regulation of secretionGO:0051048580.244
thalamus developmentGO:002179420.242
motor neuron axon guidanceGO:000804520.241
innate immune response activating signal transductionGO:0002758480.239
endocytosisGO:00068971590.238
regulation of gtpase activityGO:00430871800.236
p38mapk cascadeGO:003806690.236
regulation of cell developmentGO:00602841610.235
nucleoside triphosphate catabolic processGO:00091433940.235
regulation of protein complex assemblyGO:00432541470.234
regulation of secretionGO:00510461940.234
cardioblast cell fate specificationGO:004268510.233
long term synaptic potentiationGO:006029110.232
positive regulation of peptidyl tyrosine phosphorylationGO:0050731850.232
single organism reproductive processGO:0044702980.230
positive regulation of sequence specific dna binding transcription factor activityGO:00510911310.230
cochlea developmentGO:009010210.229
regulation of actin filament polymerizationGO:0030833500.225
inner ear morphogenesisGO:004247240.223
endosomal transportGO:00161971290.222
cardiovascular system developmentGO:00723582620.221
cytoskeleton dependent intracellular transportGO:0030705210.220
cerebral cortex developmentGO:0021987100.219
hexose metabolic processGO:0019318550.219
regulation of actin filament bundle assemblyGO:0032231360.219
regulation of cell cycleGO:00517263930.216
astrocyte cell migrationGO:004361510.216
regulation of peptidyl tyrosine phosphorylationGO:00507301080.215
cellular chemical homeostasisGO:00550821800.213
cell surface receptor signaling pathway involved in heart developmentGO:006131180.213
retina vasculature development in camera type eyeGO:006129830.208
mitotic cell cycle processGO:19030472860.208
regulation of icosanoid secretionGO:003230340.207
establishment of cell polarityGO:0030010220.207
positive regulation of immune system processGO:00026842830.206
morphogenesis of an epitheliumGO:0002009600.205
actin filament polymerizationGO:0030041450.205
positive regulation of protein import into nucleusGO:0042307460.204
response to lipidGO:00339932060.204
defense responseGO:00069523150.202
cellular response to mechanical stimulusGO:0071260390.199
digestive tract developmentGO:0048565750.198
positive regulation of icosanoid secretionGO:003230530.198
behaviorGO:00076101120.197
cardiac cell fate specificationGO:006091210.197
positive regulation of prostaglandin secretionGO:003230810.195
gtp metabolic processGO:00460392390.195
neural tube patterningGO:002153220.195
negative regulation of cardiac cell fate specificationGO:200004410.191
cellular macromolecular complex assemblyGO:00346223240.190
peptidyl serine modificationGO:00182091060.190
nuclear divisionGO:00002801280.189
cellular ion homeostasisGO:00068731680.188
somatic stem cell divisionGO:004810310.188
regulation of apoptotic signaling pathwayGO:20012331750.187
atp metabolic processGO:00460341760.187
regulation of cell cell adhesion mediated by cadherinGO:200004740.187
cell migration involved in gastrulationGO:004207410.184
cell projection assemblyGO:00300311260.184
negative regulation of transferase activityGO:00513481240.182
metal ion homeostasisGO:00550651690.182
startle responseGO:000196430.181
vacuolar transportGO:0007034340.181
endodermal cell fate specificationGO:000171440.179
cation homeostasisGO:00550801890.178
positive regulation of stress activated protein kinase signaling cascadeGO:0070304610.178
positive regulation of actin filament polymerizationGO:0030838380.176
regulation of lamellipodium morphogenesisGO:200039240.176
positive regulation of intracellular protein transportGO:0090316760.175
positive regulation of myoblast fusionGO:190174110.173
cerebral cortex cell migrationGO:002179530.173
digestive system developmentGO:0055123750.173
regulation of receptor mediated endocytosisGO:0048259320.172
calcium ion homeostasisGO:00550741220.170
cation transportGO:00068123310.170
membrane fusionGO:0061025430.168
apoptotic mitochondrial changesGO:0008637570.168
modification dependent macromolecule catabolic processGO:00436322120.166
Mouse
positive regulation of secretionGO:00510471160.165
regulation of mitochondrion organizationGO:0010821540.165
regulation of nervous system developmentGO:0051960880.161
organic acid transportGO:0015849650.161
regulation of neuron differentiationGO:0045664700.160
negative regulation of kinase activityGO:00336731060.160
fatty acid transportGO:0015908250.159
innate immune responseGO:00450871780.157
protein processingGO:00164852260.155
positive regulation of innate immune responseGO:0045089790.154
cochlea morphogenesisGO:009010310.153
negative regulation of phosphorus metabolic processGO:00105632670.153
regulation of synaptic plasticityGO:004816730.153
regulation of prostaglandin secretionGO:003230620.153
negative regulation of stem cell differentiationGO:2000737220.151
positive regulation of nitric oxide synthase biosynthetic processGO:005177030.151
negative regulation of protein serine threonine kinase activityGO:0071901570.151
organic anion transportGO:00157111030.150
gastrulationGO:0007369510.150
endosome organizationGO:0007032200.149
cellular protein catabolic processGO:00442572610.148
Mouse
mucopolysaccharide metabolic processGO:1903510270.145
metal ion transportGO:00300012720.145
regulation of cell cycle processGO:00105642660.144
regulation of establishment of protein localizationGO:00702012420.142
immune responseGO:00069553070.141
positive regulation of cell developmentGO:0010720920.141
filopodium assemblyGO:0046847180.141
chromatin organizationGO:00063253510.141
retinal blood vessel morphogenesisGO:006130420.141
cellular lipid metabolic processGO:00442553030.138
digestive tract morphogenesisGO:0048546560.138
mitochondrion transport along microtubuleGO:004749730.138
heart morphogenesisGO:0003007480.137
regulation of lipid transportGO:0032368440.137
negative regulation of transportGO:00510511760.137
calcium ion transportGO:00068161470.137
regulation of gtp catabolic processGO:00331241800.136
hindbrain developmentGO:003090230.135
negative regulation of phosphorylationGO:00423261740.135
Mouse
neurological system processGO:00508771630.135
positive regulation of secretion by cellGO:19035321080.134
secretion by cellGO:00329402260.133
female gamete generationGO:000729220.133
regulation of cardiac muscle tissue developmentGO:0055024130.133
monosaccharide metabolic processGO:0005996740.133
neuron projection morphogenesisGO:0048812500.133
regulation of wnt signaling pathway planar cell polarity pathwayGO:200009520.133
neural tube developmentGO:002191590.132
cell part morphogenesisGO:00329901370.131
regulation of ion transmembrane transportGO:00347651320.131
response to organonitrogen compoundGO:00102431560.131
axonogenesisGO:0007409310.129
Worm
embryonic camera type eye developmentGO:003107620.128
regulation of locomotionGO:00400123290.128
regulation of endopeptidase activityGO:00525481700.127
positive regulation of nucleoside metabolic processGO:00459791860.127
endosome transport via multivesicular body sorting pathwayGO:003250930.127
ion homeostasisGO:00508012300.124
cell cell signaling involved in cell fate commitmentGO:004516850.124
receptor mediated endocytosisGO:0006898840.124
cellular metal ion homeostasisGO:00068751460.123
axon extensionGO:0048675130.123
Worm
regulation of stress activated protein kinase signaling cascadeGO:0070302850.123
embryonic hindlimb morphogenesisGO:003511620.122
positive regulation of ossificationGO:0045778320.122
cell activationGO:00017752130.122
microtubule based processGO:00070172100.120
Fly
regulation of exocytosisGO:0017157460.119
organ inductionGO:000175940.119
positive regulation of apoptotic signaling pathwayGO:2001235700.119
regulation of protein processingGO:00706131500.118
embryonic eye morphogenesisGO:004804820.118
intracellular receptor signaling pathwayGO:00305221040.117
morphogenesis of an epithelial sheetGO:0002011120.117
regulation of defense responseGO:00313471540.116
activation of mapkk activityGO:0000186180.116
regulation of protein catabolic processGO:00421761550.116
Mouse
oxidation reduction processGO:00551143960.114
metencephalon developmentGO:002203720.113
actin filament bundle assemblyGO:0051017540.113
positive regulation of gtpase activityGO:00435471660.113
cell morphogenesis involved in neuron differentiationGO:0048667440.112
mitotic nuclear divisionGO:00070671190.112
regulation of transmembrane transportGO:00347621390.112
single organism membrane fusionGO:0044801370.111
organ formationGO:004864530.110
protein localization to cytoskeletonGO:0044380110.109
carbohydrate biosynthetic processGO:0016051420.109
lamellipodium assemblyGO:0030032260.109
adult locomotory behaviorGO:000834410.109
regulation of cell morphogenesis involved in differentiationGO:0010769830.109
regulation of jun kinase activityGO:0043506270.108
meiotic chromosome segregationGO:004513240.107
regulation of wnt signaling pathway involved in heart developmentGO:000330730.106
response to mechanical stimulusGO:0009612510.106
positive regulation of myotube differentiationGO:001083130.106
cilium organizationGO:0044782680.105
activation of mapkkk activityGO:000018570.105
positive regulation of cell proliferationGO:00082843010.104
positive regulation of protein transportGO:00512221350.104
termination of signal transductionGO:002302130.104
positive regulation of proteolysisGO:00458621420.104
Mouse
syncytium formation by plasma membrane fusionGO:000076820.104
protein importGO:00170381300.104
negative regulation of protein metabolic processGO:00512483910.103
circulatory system developmentGO:00723592620.102
neurogenesisGO:00220081690.102
post golgi vesicle mediated transportGO:0006892360.101
response to oxidative stressGO:00069791210.101
cell growthGO:00160491600.100
Worm
establishment of spindle localizationGO:0051293120.100
peptidyl threonine phosphorylationGO:0018107410.099
positive regulation of fat cell differentiationGO:0045600120.099

LRRK2 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
parkinson s diseaseDOID:14330180.117
synucleinopathyDOID:0050890220.117
central nervous system diseaseDOID:3311860.117
neurodegenerative diseaseDOID:12891020.117
nervous system diseaseDOID:8634310.117