Homo sapiens

36 known processes

INVS

inversin

(Aliases: NPH2,KIAA0573,INV,NPHP2,MGC133081,MGC133080)

INVS biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
establishment of planar polarityGO:000173630.248
cilium morphogenesisGO:0060271750.166
determination of adult lifespanGO:000834020.126
cilium organizationGO:0044782680.118
morphogenesis of a polarized epitheliumGO:000173830.109
multicellular organismal agingGO:001025930.105
establishment of tissue polarityGO:000716430.084
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.081
positive regulation of developmental processGO:00510943140.080
cilium assemblyGO:0042384630.070
cell morphogenesisGO:00009022960.063
female gamete generationGO:000729220.062
regulation of cell differentiationGO:00455953930.060
oxidation reduction processGO:00551143960.059
anatomical structure formation involved in morphogenesisGO:00486462840.058
cellular amino acid metabolic processGO:00065201160.055
cellular component morphogenesisGO:00329893140.053
post embryonic developmentGO:000979120.052
Mouse
amine metabolic processGO:0009308440.052
cell projection assemblyGO:00300311260.051
cellular amine metabolic processGO:0044106410.047
organelle assemblyGO:00709251760.047
cell projection organizationGO:00300302520.046
positive regulation of cell differentiationGO:00455972110.045
positive regulation of cellular component organizationGO:00511303760.045
regulation of cellular amino acid metabolic processGO:000652160.044
response to abiotic stimulusGO:00096283360.042
epithelium developmentGO:00604292270.041
Mouse
cellular component assembly involved in morphogenesisGO:0010927730.040
regulation of cellular amine metabolic processGO:0033238110.040
behaviorGO:00076101120.036
cellular ketone metabolic processGO:0042180800.036
cell developmentGO:00484683280.035
regulation of cellular ketone metabolic processGO:0010565500.035
protein ubiquitinationGO:00165673140.034
protein localization to organelleGO:00333652800.034
positive regulation of cellular amino acid metabolic processGO:004576430.033
negative regulation of transcription from rna polymerase ii promoter in response to hypoxiaGO:006142840.033
purine containing compound catabolic processGO:00725234110.033
ribonucleoside triphosphate metabolic processGO:00091994120.032
wnt signaling pathwayGO:00160551560.032
nucleoside catabolic processGO:00091644080.032
nucleoside phosphate catabolic processGO:19012924120.032
ras protein signal transductionGO:0007265730.032
protein modification by small protein conjugationGO:00324463420.031
purine ribonucleoside triphosphate catabolic processGO:00092073910.031
positive regulation of catabolic processGO:00098963100.031
nucleoside triphosphate metabolic processGO:00091414220.030
oogenesisGO:004847720.030
purine ribonucleoside metabolic processGO:00461284370.030
cellular macromolecular complex assemblyGO:00346223240.029
positive regulation of myoblast differentiationGO:004566360.028
mitotic cell cycleGO:00002783260.028
locomotory behaviorGO:000762610.028
ribonucleotide catabolic processGO:00092614050.028
purine ribonucleoside catabolic processGO:00461303980.028
positive regulation of cellular amine metabolic processGO:003324070.027
organophosphate catabolic processGO:00464344300.027
nucleoside triphosphate catabolic processGO:00091433940.026
purine nucleoside triphosphate metabolic processGO:00091444120.026
cell part morphogenesisGO:00329901370.026
purine nucleotide catabolic processGO:00061954050.026
regulation of cell cycleGO:00517263930.026
negative regulation of catalytic activityGO:00430863350.026
purine nucleoside triphosphate catabolic processGO:00091463920.025
lipid metabolic processGO:00066293810.025
negative regulation of cellular protein metabolic processGO:00322693530.025
glycosyl compound catabolic processGO:19016584130.025
negative regulation of protein metabolic processGO:00512483910.025
regulation of cellular component biogenesisGO:00440872810.025
cell projection morphogenesisGO:00488581290.025
purine ribonucleoside triphosphate metabolic processGO:00092054110.025
nucleotide catabolic processGO:00091664080.025
positive regulation of phosphorylationGO:00423273940.025
regulation of cell cycle processGO:00105642660.025
cytoplasmic transportGO:00164823790.025
purine nucleoside catabolic processGO:00061523980.025
ribonucleoside catabolic processGO:00424544060.025
ribonucleoside triphosphate catabolic processGO:00092033910.024
immune responseGO:00069553070.024
regulation of cell developmentGO:00602841610.024
purine ribonucleotide catabolic processGO:00091544040.024
cellular protein complex assemblyGO:00436231880.024
hindbrain developmentGO:003090230.024
negative regulation of phosphorus metabolic processGO:00105632670.024
neuromuscular junction developmentGO:000752830.024
regulation of cell motilityGO:20001452990.024
regulation of kinase activityGO:00435493140.024
regulation of transferase activityGO:00513383550.024
positive regulation of transportGO:00510503360.024
regulation of nucleotide metabolic processGO:00061402690.023
regulation of striated muscle cell differentiationGO:0051153250.023
protein catabolic processGO:00301633250.023
signal transduction by phosphorylationGO:00230142970.023
motor neuron axon guidanceGO:000804520.023
memoryGO:000761330.022
segmentationGO:003528240.022
positive regulation of hydrolase activityGO:00513453310.022
positive regulation of cellular catabolic processGO:00313312840.022
cellular response to decreased oxygen levelsGO:0036294510.022
mitotic cell cycle processGO:19030472860.022
release of cytoplasmic sequestered nf kappabGO:000858840.022
negative regulation of programmed cell deathGO:00430693210.022
positive regulation of protein phosphorylationGO:00019343130.021
cellular lipid metabolic processGO:00442553030.021
negative regulation of cell deathGO:00605483450.021
carbohydrate metabolic processGO:00059752070.021
regulation of cellular component movementGO:00512703340.021
actin filament based processGO:00300292240.021
regulation of muscle cell differentiationGO:0051147310.021
anterior posterior axis specificationGO:000994820.021
cellular response to dna damage stimulusGO:00069743790.021
photoreceptor cell differentiationGO:004653020.020
positive regulation of cell deathGO:00109422630.020
vesicle mediated transportGO:00161923710.020
cellular macromolecule catabolic processGO:00442653800.020
dephosphorylationGO:00163112090.020
chromatin modificationGO:00165682980.020
regulation of muscle organ developmentGO:0048634270.020
positive regulation of transferase activityGO:00513472270.020
negative regulation of phosphate metabolic processGO:00459362670.020
morphogenesis of embryonic epitheliumGO:001633140.020
positive regulation of programmed cell deathGO:00430682490.020
single organism cellular localizationGO:19025803320.020
small gtpase mediated signal transductionGO:0007264780.020
negative regulation of cellular amine metabolic processGO:003323930.020
protein maturationGO:00516042330.020
regenerationGO:003109940.020
peripheral nervous system developmentGO:000742220.019
apoptotic signaling pathwayGO:00971902680.019
regulation of proteolysisGO:00301622930.019
spermatid differentiationGO:004851540.019
associative learningGO:000830610.019
regulation of dna metabolic processGO:00510521530.019
cell adhesionGO:00071553250.019
histone modificationGO:00165702510.019
regulation of cell migrationGO:00303342890.019
defense responseGO:00069523150.019
negative regulation of cell cycleGO:00457861930.019
covalent chromatin modificationGO:00165692540.019
regulation of sequence specific dna binding transcription factor activityGO:00510902110.019
positive regulation of cellular component movementGO:00512721810.019
response to biotic stimulusGO:00096072760.018
canonical wnt signaling pathwayGO:00600701160.018
response to hypoxiaGO:0001666960.018
regulation of purine nucleotide metabolic processGO:19005422640.018
blastoderm segmentationGO:000735020.018
rho protein signal transductionGO:0007266260.018
regulation of bindingGO:00510981110.018
innate immune responseGO:00450871780.018
cellular protein catabolic processGO:00442572610.018
matingGO:000761810.018
cellular response to endogenous stimulusGO:00714953360.018
positive regulation of muscle cell differentiationGO:0051149150.018
regulation of protein localizationGO:00328802960.018
cell cycle phase transitionGO:00447701730.018
positive regulation of cell proliferationGO:00082843010.018
nervous system developmentGO:00073992930.018
oocyte differentiationGO:000999420.018
negative regulation of cell proliferationGO:00082852280.018
metencephalon developmentGO:002203720.018
biological adhesionGO:00226103310.018
positive regulation of immune system processGO:00026842830.018
negative regulation of multicellular organismal processGO:00512413170.018
regulation of cellular response to stressGO:00801352440.018
mapk cascadeGO:00001652880.018
transmembrane transportGO:00550853990.018
cation transmembrane transportGO:00986552380.018
response to cytokineGO:00340972320.018
microtubule based processGO:00070172100.018
regulation of protein kinase activityGO:00458592890.017
negative regulation of intracellular signal transductionGO:19025321830.017
anatomical structure homeostasisGO:00602491000.017
organonitrogen compound biosynthetic processGO:19015662000.017
regulation of establishment of protein localizationGO:00702012420.017
regulation of locomotionGO:00400123290.017
ion homeostasisGO:00508012300.017
response to other organismGO:00517072610.017
chromatin organizationGO:00063253510.017
embryonic epithelial tube formationGO:000183840.017
cellular response to cytokine stimulusGO:00713451810.017
negative regulation of cellular amino acid metabolic processGO:004576320.017
cellular response to oxygen containing compoundGO:19017012760.017
dna replicationGO:00062601160.017
adult locomotory behaviorGO:000834410.017
regulation of mapk cascadeGO:00434082620.017
membrane organizationGO:00610242920.016
positive regulation of cytokine productionGO:00018191670.016
inorganic cation transmembrane transportGO:00986621940.016
positive regulation of nucleotide metabolic processGO:00459812300.016
cellular cation homeostasisGO:00300031630.016
negative regulation of hydrolase activityGO:00513461820.016
salivary gland morphogenesisGO:000743540.016
single organism membrane organizationGO:00448022680.016
cation transportGO:00068123310.016
nitrogen compound transportGO:00717051910.016
oocyte developmentGO:004859910.016
rhythmic behaviorGO:000762220.016
system processGO:00030083490.016
rna processingGO:00063962550.016
protein processingGO:00164852260.016
regulation of anatomical structure morphogenesisGO:00226032860.016
negative regulation of protein modification processGO:00314002000.016
regulation of protein transportGO:00512232130.016
cell fate determinationGO:000170930.016
muscle tissue developmentGO:0060537620.016
response to oxygen containing compoundGO:19017003690.016
response to oxygen levelsGO:00704821000.016
ion transmembrane transportGO:00342203380.016
regulation of intracellular transportGO:00323861950.016
cation homeostasisGO:00550801890.016
secretionGO:00469032540.016
negative regulation of apoptotic processGO:00430663160.016
enzyme linked receptor protein signaling pathwayGO:00071673030.016
cell growthGO:00160491600.016
regulation of myotube differentiationGO:0010830180.015
regulation of immune responseGO:00507762010.015
maintenance of locationGO:00512351120.015
negative regulation of phosphorylationGO:00423261740.015
response to decreased oxygen levelsGO:0036293960.015
spermatid developmentGO:000728640.015
regulation of purine nucleotide catabolic processGO:00331212050.015
regulation of secretionGO:00510461940.015
small molecule biosynthetic processGO:00442831570.015
visual behaviorGO:000763220.015
negative regulation of developmental processGO:00510932470.015
regulation of response to external stimulusGO:00321012220.015
cellular chemical homeostasisGO:00550821800.015
response to external biotic stimulusGO:00432072610.015
organ formationGO:004864530.015
nucleoside monophosphate metabolic processGO:00091231910.015
myoblast differentiationGO:0045445210.015
compound eye developmentGO:004874910.015
regulation of wnt signaling pathwayGO:00301111230.015
protein targetingGO:00066051870.015
ribonucleoside monophosphate catabolic processGO:00091581580.015
guanosine containing compound catabolic processGO:19010692390.015
mitotic cell cycle phase transitionGO:00447721620.015
positive regulation of protein kinase activityGO:00458601900.015
protein acylationGO:00435431380.015
agingGO:0007568660.015
hemopoiesisGO:00300971800.015
macromolecule glycosylationGO:0043413630.015
protein hydroxylationGO:001812690.014
nerve developmentGO:002167540.014
positive regulation of purine nucleotide metabolic processGO:19005442270.014
positive regulation of nucleoside metabolic processGO:00459791860.014
growthGO:00400072020.014
organophosphate biosynthetic processGO:00904071630.014
glycosylationGO:0070085710.014
negative regulation of cellular component organizationGO:00511292350.014
positive regulation of gtpase activityGO:00435471660.014
neural tube formationGO:000184130.014
regulation of striated muscle tissue developmentGO:0016202260.014
gtp metabolic processGO:00460392390.014
sequestering of calcium ionGO:0051208170.014
secretion by cellGO:00329402260.014
protein oligomerizationGO:00512591730.014
metal ion homeostasisGO:00550651690.014
response to radiationGO:00093141510.014
ribonucleoside monophosphate metabolic processGO:00091611870.014
purine nucleoside monophosphate metabolic processGO:00091261860.014
reactive oxygen species biosynthetic processGO:190340940.014
cellular ion homeostasisGO:00068731680.014
regulation of cell morphogenesisGO:00226041530.014
peptidyl serine modificationGO:00182091060.014
positive regulation of purine nucleotide catabolic processGO:00331231850.014
regulation of chromosome organizationGO:00330441030.014
cerebellum developmentGO:002154920.014
cytokine productionGO:00018162470.014
response to nitrogen compoundGO:19016981840.014
regulation of transcription from rna polymerase ii promoter mitoticGO:004602110.014
positive regulation of gtp catabolic processGO:00331261660.014
regulation of cytoplasmic transportGO:19036491490.014
neurotransmitter secretionGO:000726940.014
lipid biosynthetic processGO:00086101770.014
regulation of canonical wnt signaling pathwayGO:0060828880.014
i kappab kinase nf kappab signalingGO:00072491660.014
neurological system processGO:00508771630.014
purine ribonucleoside monophosphate metabolic processGO:00091671860.014
regulation of neural precursor cell proliferationGO:200017740.014
establishment of protein localization to organelleGO:00725941720.014
metal ion transportGO:00300012720.014
glycoprotein biosynthetic processGO:0009101910.014
positive regulation of immune responseGO:00507781590.014
positive regulation of apoptotic processGO:00430652460.014
positive regulation of synaptic transmissionGO:005080640.014
regulation of gtp catabolic processGO:00331241800.013
tripartite regional subdivisionGO:000735120.013
gtp catabolic processGO:00061842370.013
regulation of synaptic plasticityGO:004816730.013
intracellular protein transportGO:00068862700.013
regulation of nucleoside metabolic processGO:00091182090.013
dna repairGO:00062811980.013
positive regulation of cell migrationGO:00303351720.013
visual learningGO:000854210.013
positive regulation of cell motilityGO:20001471770.013
response to growth factorGO:00708482050.013
positive regulation of kinase activityGO:00336742040.013
reactive nitrogen species metabolic processGO:200105730.013
sequestering of metal ionGO:0051238240.013
positive regulation of locomotionGO:00400171860.013
actin cytoskeleton organizationGO:00300362070.013
epithelium migrationGO:00901321190.013
rna interferenceGO:001624640.013
cellular metal ion homeostasisGO:00068751460.013
positive regulation of nucleotide catabolic processGO:00308131850.013
endomembrane system organizationGO:00102561960.013
regulation of myoblast differentiationGO:0045661120.013
chemical homeostasisGO:00488783060.013
guanosine containing compound metabolic processGO:19010682440.013
meiosis iGO:000712740.013
regulation of growthGO:00400081650.013
neuron projection regenerationGO:003110210.013
regulation of protein processingGO:00706131500.013
nucleoside monophosphate catabolic processGO:00091251590.013
anterior posterior axis specification embryoGO:000859520.013
negative regulation of cell cycle processGO:00109481210.013
regulation of mitotic cell cycleGO:00073461890.013
hematopoietic or lymphoid organ developmentGO:00485341860.013
positive regulation of transcription from rna polymerase ii promoter during mitosisGO:004602210.013
inner ear morphogenesisGO:004247240.013
cell divisionGO:00513011680.013
monocarboxylic acid metabolic processGO:00327871850.013
muscle structure developmentGO:0061061980.013
regulation of transcription during mitosisGO:004589620.013
regulation of nucleotide catabolic processGO:00308112050.013
regulation of cytokine productionGO:00018172320.013
posttranscriptional regulation of gene expressionGO:00106082130.012
peptidyl asparagine modificationGO:0018196110.012
modification dependent macromolecule catabolic processGO:00436322120.012
nuclear transportGO:00511691790.012
mitochondrion organizationGO:00070051560.012
positive regulation of mapk cascadeGO:00434101900.012
regulation of cell growthGO:00015581350.012
actin filament based movementGO:0030048170.012
cellular homeostasisGO:00197251960.012
regulation of defense responseGO:00313471540.012
positive regulation of dna metabolic processGO:0051054730.012
cardiac muscle cell contractionGO:008600340.012
regulation of protein maturationGO:19033171500.012
regulation of reactive oxygen species biosynthetic processGO:190342630.012
negative regulation of transferase activityGO:00513481240.012
morphogenesis of an epitheliumGO:0002009600.012
inorganic ion transmembrane transportGO:00986602310.012
tissue migrationGO:00901301190.012
positive regulation of protein catabolic processGO:0045732750.012
regulation of gtpase activityGO:00430871800.012
carbohydrate derivative biosynthetic processGO:19011372070.012
regulation of meiotic cell cycleGO:005144540.012
regulation of apoptotic signaling pathwayGO:20012331750.012
single organism cell adhesionGO:00986021790.012
sensory perception of painGO:001923340.012
notch signaling pathwayGO:0007219310.012
atp metabolic processGO:00460341760.012
positive regulation of transcription during mitosisGO:004589720.012
cellular response to growth factor stimulusGO:00713631970.012
reactive oxygen species metabolic processGO:0072593750.012
ncrna metabolic processGO:00346601080.012
protein dephosphorylationGO:0006470810.012
ubiquitin dependent protein catabolic processGO:00065112060.012
negative regulation of proteolysisGO:00458611320.012
proteasomal protein catabolic processGO:00104981760.012
peptidyl lysine modificationGO:00182051440.012
atp catabolic processGO:00062001570.012
immune system developmentGO:00025201950.012
response to axon injuryGO:004867810.012
regulation of small gtpase mediated signal transductionGO:00510561560.012
negative regulation of protein phosphorylationGO:00019331400.012
proteolysis involved in cellular protein catabolic processGO:00516032440.012
peptidyl serine phosphorylationGO:00181051010.012
endosomal transportGO:00161971290.012
microtubule cytoskeleton organizationGO:00002261760.011
endocytosisGO:00068971590.011
actin mediated cell contractionGO:0070252120.011
peptidyl tyrosine modificationGO:00182121700.011
muscle cell cellular homeostasisGO:004671630.011
endodermal cell fate commitmentGO:000171140.011
protein homooligomerizationGO:00512601000.011
tissue regenerationGO:004224630.011
negative regulation of protein processingGO:00109551420.011
response to fungusGO:000962040.011
stem cell divisionGO:001714520.011
regulation of cell cycle phase transitionGO:19019871260.011
somatic stem cell maintenanceGO:003501940.011
syncytium formation by plasma membrane fusionGO:000076820.011
generation of neuronsGO:00486991520.011
cellular response to nitrogen compoundGO:19016991440.011
neural crest cell developmentGO:001403230.011
purine ribonucleoside monophosphate catabolic processGO:00091691580.011
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.011
positive regulation of hormone biosynthetic processGO:004688640.011
somitogenesisGO:000175620.011
neuroblast proliferationGO:000740540.011
organic hydroxy compound metabolic processGO:19016151470.011
limbic system developmentGO:002176130.011
protein localization to nucleusGO:00345041360.011
nucleus localizationGO:005164710.011
positive regulation of protein transportGO:00512221350.011
activation of immune responseGO:00022531140.011
regulation of neurotransmitter secretionGO:004692830.011
myosin filament organizationGO:003103320.011
nucleocytoplasmic transportGO:00069131760.011
alcohol metabolic processGO:00060661140.011
regulation of ras gtpase activityGO:00323181280.011
regulation of i kappab kinase nf kappab signalingGO:00431221620.011
protein importGO:00170381300.011
circadian behaviorGO:004851220.011
regulation of peptidase activityGO:00525471800.011
neuron developmentGO:00486661130.011
divalent inorganic cation transportGO:00725111580.011
central nervous system developmentGO:00074171230.011
regulation of response to dna damage stimulusGO:2001020940.011
chemotaxisGO:00069351570.011
positive regulation of secretionGO:00510471160.011
regulation of ion transportGO:00432691890.011
circulatory system developmentGO:00723592620.011
Mouse
nuclear importGO:00511701060.011
negative regulation of synaptic transmissionGO:005080520.011
negative regulation of organelle organizationGO:00106391260.011
methylationGO:00322591060.011
muscle cell differentiationGO:0042692630.011
positive regulation of reactive oxygen species biosynthetic processGO:190342820.011
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.011
plasma membrane organizationGO:00070091150.011
spinal cord developmentGO:002151040.010
neural tube closureGO:000184330.010
cardiovascular system developmentGO:00723582620.010
Mouse
positive regulation of ras gtpase activityGO:00323201170.010
negative regulation of transportGO:00510511760.010
cell substrate adhesionGO:00315891320.010
long term memoryGO:000761620.010
regulation of cell adhesionGO:00301551660.010
lung alveolus developmentGO:004828640.010
positive regulation of i kappab kinase nf kappab signalingGO:00431231320.010
regulation of dna replicationGO:0006275680.010
regulation of endopeptidase activityGO:00525481700.010
myosin filament assemblyGO:003103420.010
negative regulation of immune system processGO:00026831360.010
modification dependent protein catabolic processGO:00199412090.010
negative regulation of protein maturationGO:19033181420.010
regulation of cytoskeleton organizationGO:00514931770.010
tube closureGO:006060630.010
purine nucleoside monophosphate catabolic processGO:00091281580.010
cytokine mediated signaling pathwayGO:00192211090.010
response to virusGO:00096151260.010
sensory perceptionGO:00076001030.010
divalent metal ion transportGO:00708381520.010
regulation of dephosphorylationGO:0035303960.010
negative regulation of cell differentiationGO:00455961710.010
ameboidal type cell migrationGO:00016671350.010
peptidyl threonine modificationGO:0018210450.010
regulation of jnk cascadeGO:0046328730.010
regulation of ras protein signal transductionGO:00465781550.010
organelle fissionGO:00482851490.010
regulation of mitotic cell cycle phase transitionGO:19019901180.010
fatty acid metabolic processGO:00066311150.010
neurogenesisGO:00220081690.010
developmental programmed cell deathGO:001062330.010
t cell differentiation in thymusGO:003307740.010
epidermis morphogenesisGO:004873030.010
thymus developmentGO:004853830.010
cell activationGO:00017752130.010

INVS disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
meckel syndromeDOID:0050778110.986
disease of metabolismDOID:00146672950.035
inherited metabolic disorderDOID:6552420.025
sensory system diseaseDOID:00501552030.023
nervous system diseaseDOID:8634310.023
musculoskeletal system diseaseDOID:172230.023
central nervous system diseaseDOID:3311860.021
immune system diseaseDOID:29141550.019
eye diseaseDOID:56141490.018
eye and adnexa diseaseDOID:14921500.018
disease of cellular proliferationDOID:145661740.018
cancerDOID:1621670.018
organ system cancerDOID:00506861640.017
connective tissue diseaseDOID:651090.016
retinal diseaseDOID:56791180.015
bone diseaseDOID:0080001880.014
cardiovascular system diseaseDOID:12871060.013
neurodegenerative diseaseDOID:12891020.013
muscular diseaseDOID:00800001140.012
muscle tissue diseaseDOID:661130.012
myopathyDOID:4231040.012
retinal degenerationDOID:8466890.012
hematopoietic system diseaseDOID:741000.011
nephronophthisisDOID:12712130.003