Homo sapiens

100 known processes

AIFM1

apoptosis-inducing factor, mitochondrion-associated, 1

(Aliases: MGC111425,COXPD6,AIF,PDCD8)

AIFM1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
determination of adult lifespanGO:000834020.843
dicarboxylic acid metabolic processGO:0043648290.810
post embryonic developmentGO:000979120.762
Worm
multicellular organismal agingGO:001025930.538
oxidation reduction processGO:00551143960.512
mitochondrion organizationGO:00070051560.462
cofactor biosynthetic processGO:0051188310.458
activation of cysteine type endopeptidase activity involved in apoptotic processGO:0006919490.419
carboxylic acid catabolic processGO:0046395710.391
aerobic respirationGO:000906070.377
embryo developmentGO:00097901230.299
Worm
generation of precursor metabolites and energyGO:0006091680.289
vesicle mediated transportGO:00161923710.280
Worm
monocarboxylic acid metabolic processGO:00327871850.274
citrate metabolic processGO:000610120.266
positive regulation of apoptotic processGO:00430652460.266
glutamine family amino acid metabolic processGO:0009064170.257
glutamate metabolic processGO:0006536100.247
glutamine family amino acid biosynthetic processGO:000908450.189
tricarboxylic acid metabolic processGO:007235040.188
nucleoside triphosphate metabolic processGO:00091414220.188
purine ribonucleoside monophosphate metabolic processGO:00091671860.179
organic acid catabolic processGO:0016054710.176
purine nucleoside triphosphate metabolic processGO:00091444120.173
nucleoside monophosphate metabolic processGO:00091231910.168
2 oxoglutarate metabolic processGO:000610340.166
dicarboxylic acid catabolic processGO:004364990.162
female gamete generationGO:000729220.162
energy derivation by oxidation of organic compoundsGO:0015980430.161
cofactor metabolic processGO:0051186870.159
mitochondrial membrane organizationGO:0007006400.158
mitochondrial transportGO:0006839600.151
atp metabolic processGO:00460341760.151
glycerol metabolic processGO:000607140.150
coenzyme metabolic processGO:0006732650.150
lipid metabolic processGO:00066293810.150
cellular amino acid metabolic processGO:00065201160.146
carbohydrate metabolic processGO:00059752070.145
positive regulation of peptidase activityGO:0010952880.144
acetyl coa biosynthetic process from pyruvateGO:000608640.143
tricarboxylic acid cycleGO:000609940.142
positive regulation of hydrolase activityGO:00513453310.138
regulation of membrane potentialGO:0042391950.134
cellular amino acid biosynthetic processGO:0008652300.130
small molecule biosynthetic processGO:00442831570.128
fatty acid metabolic processGO:00066311150.122
cellular respirationGO:0045333210.121
purine ribonucleoside metabolic processGO:00461284370.119
dicarboxylic acid biosynthetic processGO:004365040.109
sulfur compound biosynthetic processGO:0044272380.107
purine ribonucleoside triphosphate metabolic processGO:00092054110.101
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.093
oogenesisGO:004847720.092
endocytosisGO:00068971590.091
Worm
purine nucleoside monophosphate metabolic processGO:00091261860.091
cell developmentGO:00484683280.087
sulfur compound metabolic processGO:00067901010.086
small molecule catabolic processGO:0044282920.081
aspartate metabolic processGO:000653140.081
ribonucleoside triphosphate metabolic processGO:00091994120.079
activation of cysteine type endopeptidase activityGO:0097202570.076
cellular amino acid catabolic processGO:0009063310.073
protein processingGO:00164852260.071
oxidative phosphorylationGO:0006119100.071
mitochondrial atp synthesis coupled electron transportGO:004277540.068
regulation of endopeptidase activityGO:00525481700.067
membrane organizationGO:00610242920.066
mitochondrial electron transport nadh to ubiquinoneGO:000612020.062
neuromuscular junction developmentGO:000752830.062
cellular lipid metabolic processGO:00442553030.061
alpha amino acid catabolic processGO:1901606260.061
alpha amino acid metabolic processGO:1901605720.061
system processGO:00030083490.060
aspartate family amino acid catabolic processGO:000906850.058
ribonucleoside monophosphate metabolic processGO:00091611870.057
embryo development ending in birth or egg hatchingGO:0009792340.057
Worm
acyl coa biosynthetic processGO:007161660.052
receptor mediated endocytosisGO:0006898840.052
Worm
protein maturationGO:00516042330.052
single organism cellular localizationGO:19025803320.052
coenzyme biosynthetic processGO:0009108240.050
atp synthesis coupled electron transportGO:004277340.050
growthGO:00400072020.049
regulation of proteolysisGO:00301622930.047
regulation of cysteine type endopeptidase activityGO:20001161270.047
protein localization to mitochondrionGO:0070585250.047
alditol metabolic processGO:001940050.047
reproductionGO:0000003630.045
Worm
single organism carbohydrate metabolic processGO:00447231930.045
regulation of mitochondrial membrane permeability involved in apoptotic processGO:1902108180.043
response to drugGO:0042493810.043
carbohydrate derivative biosynthetic processGO:19011372070.043
response to organonitrogen compoundGO:00102431560.042
regulation of nucleoside metabolic processGO:00091182090.042
immune responseGO:00069553070.041
agingGO:0007568660.041
positive regulation of cell deathGO:00109422630.039
zymogen activationGO:0031638700.038
acyl coa metabolic processGO:0006637230.037
single organism reproductive processGO:0044702980.036
cellular carbohydrate metabolic processGO:0044262840.035
reactive oxygen species metabolic processGO:0072593750.035
response to hormoneGO:00097251750.035
positive regulation of endopeptidase activityGO:0010950840.034
immune system developmentGO:00025201950.033
positive regulation of programmed cell deathGO:00430682490.031
positive regulation of nucleoside metabolic processGO:00459791860.031
cellular amide metabolic processGO:0043603690.031
somatic diversification of immunoglobulins involved in immune responseGO:000220830.031
response to oxidative stressGO:00069791210.031
apoptotic mitochondrial changesGO:0008637570.029
cellular ketone metabolic processGO:0042180800.029
central nervous system developmentGO:00074171230.029
thioester metabolic processGO:0035383230.029
alcohol biosynthetic processGO:0046165520.028
negative regulation of programmed cell deathGO:00430693210.028
alpha amino acid biosynthetic processGO:1901607230.027
cellular amine metabolic processGO:0044106410.027
ion homeostasisGO:00508012300.026
spermatid differentiationGO:004851540.026
negative regulation of intracellular signal transductionGO:19025321830.025
organonitrogen compound biosynthetic processGO:19015662000.025
positive regulation of proteolysisGO:00458621420.024
cytoplasmic transportGO:00164823790.024
cellular response to oxygen containing compoundGO:19017012760.024
cellular protein complex assemblyGO:00436231880.024
ion transmembrane transportGO:00342203380.024
intracellular protein transportGO:00068862700.024
multi organism reproductive processGO:0044703540.024
thioester biosynthetic processGO:003538460.023
response to abiotic stimulusGO:00096283360.023
negative regulation of transportGO:00510511760.023
organic acid biosynthetic processGO:0016053970.023
establishment of protein localization to membraneGO:00901501210.022
rna interferenceGO:001624640.022
regulation of purine nucleotide metabolic processGO:19005422640.022
lipid localizationGO:00108761060.021
response to oxygen containing compoundGO:19017003690.021
carboxylic acid transportGO:0046942630.021
locomotory behaviorGO:000762610.021
hematopoietic or lymphoid organ developmentGO:00485341860.021
nucleoside monophosphate catabolic processGO:00091251590.021
positive regulation of cellular amino acid metabolic processGO:004576430.020
reproductive system developmentGO:0061458560.020
adult locomotory behaviorGO:000834410.020
carboxylic acid biosynthetic processGO:0046394970.020
regulation of peptidase activityGO:00525471800.020
hemopoiesisGO:00300971800.019
reproductive processGO:00224141060.019
positive regulation of cysteine type endopeptidase activityGO:2001056790.019
positive regulation of cellular catabolic processGO:00313312840.019
neurological system processGO:00508771630.019
cellular ion homeostasisGO:00068731680.019
regulation of mitochondrial membrane permeabilityGO:0046902250.018
regulation of mitochondrial membrane potentialGO:0051881230.018
regenerationGO:003109940.018
nucleoside triphosphate catabolic processGO:00091433940.018
apoptotic signaling pathwayGO:00971902680.018
respiratory chain complex iv assemblyGO:000853590.018
cellular macromolecular complex assemblyGO:00346223240.018
posttranscriptional regulation of gene expressionGO:00106082130.018
regulation of apoptotic signaling pathwayGO:20012331750.018
alcohol metabolic processGO:00060661140.018
organelle fusionGO:0048284360.018
spermatid developmentGO:000728640.018
pyruvate metabolic processGO:0006090260.017
negative regulation of growthGO:0045926970.017
establishment of protein localization to organelleGO:00725941720.017
regulation of growthGO:00400081650.017
cellular cation homeostasisGO:00300031630.017
sleepGO:003043120.017
response to other organismGO:00517072610.017
positive regulation of immune system processGO:00026842830.016
defense responseGO:00069523150.016
multi organism cellular processGO:00447641560.016
organophosphate catabolic processGO:00464344300.016
protein glycosylationGO:0006486620.016
cell cell signalingGO:00072671550.016
negative regulation of phosphorus metabolic processGO:00105632670.016
action potentialGO:0001508340.016
nucleotide catabolic processGO:00091664080.016
purine nucleoside catabolic processGO:00061523980.016
response to woundingGO:00096111680.016
transmembrane transportGO:00550853990.016
response to lipidGO:00339932060.015
positive regulation of purine nucleotide metabolic processGO:19005442270.015
positive regulation of catabolic processGO:00098963100.015
purine ribonucleoside triphosphate catabolic processGO:00092073910.015
anion transportGO:00068201610.015
wound healingGO:00420601150.015
protein targetingGO:00066051870.015
positive regulation of cellular component organizationGO:00511303760.015
cell growthGO:00160491600.015
anatomical structure homeostasisGO:00602491000.015
protein homooligomerizationGO:00512601000.014
purine ribonucleoside catabolic processGO:00461303980.014
glutamate biosynthetic processGO:000653730.014
purine nucleoside triphosphate catabolic processGO:00091463920.014
protein acylationGO:00435431380.014
chemical homeostasisGO:00488783060.014
developmental process involved in reproductionGO:0003006660.014
organic hydroxy compound metabolic processGO:19016151470.014
cellular chemical homeostasisGO:00550821800.014
developmental programmed cell deathGO:001062330.014
maintenance of locationGO:00512351120.014
behaviorGO:00076101120.014
organic acid transportGO:0015849650.014
response to cytokineGO:00340972320.013
regulation of nucleotide catabolic processGO:00308112050.013
negative regulation of cellular protein metabolic processGO:00322693530.013
lipid catabolic processGO:0016042840.013
response to peptideGO:1901652650.013
regulation of immune responseGO:00507762010.013
response to hypoxiaGO:0001666960.013
response to external biotic stimulusGO:00432072610.013
negative regulation of phosphate metabolic processGO:00459362670.012
multicellular organismal reproductive processGO:0048609400.012
ribonucleotide catabolic processGO:00092614050.012
ribonucleoside catabolic processGO:00424544060.012
innate immune responseGO:00450871780.012
mitochondrial fusionGO:0008053130.012
positive regulation of gtp catabolic processGO:00331261660.012
protein targeting to mitochondrionGO:0006626190.012
regulation of purine nucleotide catabolic processGO:00331212050.012
protein localization to organelleGO:00333652800.012
single organism membrane organizationGO:00448022680.012
negative regulation of cell proliferationGO:00082852280.012
response to organic cyclic compoundGO:00140702040.012
multicellular organism reproductionGO:0032504420.012
negative regulation of peptidase activityGO:0010466910.012
protein localization to membraneGO:00726571600.012
rna catabolic processGO:0006401710.012
organic anion transportGO:00157111030.011
protein catabolic processGO:00301633250.011
response to biotic stimulusGO:00096072760.011
regulation of behaviorGO:0050795820.011
negative regulation of protein modification processGO:00314002000.011
negative regulation of cell deathGO:00605483450.011
ribonucleoside triphosphate catabolic processGO:00092033910.011
positive regulation of immune responseGO:00507781590.011
negative regulation of cell growthGO:0030308830.011
positive regulation of nucleotide metabolic processGO:00459812300.011
ribose phosphate biosynthetic processGO:0046390820.011
immune effector processGO:00022521590.011
tissue regenerationGO:004224630.011
organic hydroxy compound biosynthetic processGO:1901617710.011
negative regulation of phosphorylationGO:00423261740.011
dephosphorylationGO:00163112090.011
amine metabolic processGO:0009308440.011
regulation of cell growthGO:00015581350.011
gtp metabolic processGO:00460392390.011
regulation of cytokine productionGO:00018172320.011
midbrain developmentGO:0030901450.011
regulation of response to external stimulusGO:00321012220.011
regulation of hormone levelsGO:00108171250.011
cellular response to hypoxiaGO:0071456510.011
response to oxygen levelsGO:00704821000.010
regulation of membrane permeabilityGO:0090559250.010
regulation of defense responseGO:00313471540.010
sex differentiationGO:0007548450.010
oxaloacetate metabolic processGO:000610710.010
positive regulation of nucleotide catabolic processGO:00308131850.010
positive regulation of developmental processGO:00510943140.010
cellular macromolecule catabolic processGO:00442653800.010
Worm
nervous system developmentGO:00073992930.010

AIFM1 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
inherited metabolic disorderDOID:6552420.977
disease of metabolismDOID:00146672950.977
amino acid metabolic disorderDOID:9252500.749
disease of cellular proliferationDOID:145661740.129
cancerDOID:1621670.129
coenzyme q10 deficiency diseaseDOID:005073060.123
mitochondrial metabolism diseaseDOID:700290.123
immune system diseaseDOID:29141550.065
sensory system diseaseDOID:00501552030.056
nervous system diseaseDOID:8634310.056
organ system cancerDOID:00506861640.046
central nervous system diseaseDOID:3311860.044
carbohydrate metabolic disorderDOID:2978550.041
eye and adnexa diseaseDOID:14921500.022
neurodegenerative diseaseDOID:12891020.018
eye diseaseDOID:56141490.016
gastrointestinal system cancerDOID:3119520.016
leigh diseaseDOID:3652160.015
neuromuscular diseaseDOID:440380.004
neuropathyDOID:870520.004
charcot marie tooth diseaseDOID:10595330.002
charcot marie tooth disease type xDOID:005054230.000