Homo sapiens

14 known processes

SACS

spastic ataxia of Charlevoix-Saguenay (sacsin)

(Aliases: ARSACS,DNAJC29,DKFZp686B15167)

SACS biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
ion transmembrane transportGO:00342203380.249
female gamete generationGO:000729220.185
amine metabolic processGO:0009308440.136
inorganic ion transmembrane transportGO:00986602310.129
regulation of cellular ketone metabolic processGO:0010565500.120
cell developmentGO:00484683280.117
cellular amine metabolic processGO:0044106410.112
lipid metabolic processGO:00066293810.109
cellular ketone metabolic processGO:0042180800.106
cellular lipid metabolic processGO:00442553030.104
regulation of cellular amino acid metabolic processGO:000652160.100
anion transportGO:00068201610.092
nervous system developmentGO:00073992930.091
morphogenesis of embryonic epitheliumGO:001633140.089
cellular amino acid metabolic processGO:00065201160.080
oogenesisGO:004847720.079
positive regulation of cellular amino acid metabolic processGO:004576430.070
mitotic cell cycleGO:00002783260.070
cation transmembrane transportGO:00986552380.069
positive regulation of cellular amine metabolic processGO:003324070.068
negative regulation of cellular protein metabolic processGO:00322693530.067
cell projection organizationGO:00300302520.067
transmembrane transportGO:00550853990.066
regulation of anatomical structure morphogenesisGO:00226032860.064
anatomical structure formation involved in morphogenesisGO:00486462840.062
cellular macromolecular complex assemblyGO:00346223240.062
cellular component morphogenesisGO:00329893140.061
cation transportGO:00068123310.059
microtubule based processGO:00070172100.056
regulation of cellular amine metabolic processGO:0033238110.054
inorganic cation transmembrane transportGO:00986621940.054
cellular response to endogenous stimulusGO:00714953360.053
microtubule cytoskeleton organizationGO:00002261760.052
cytoplasmic transportGO:00164823790.052
regulation of cell differentiationGO:00455953930.050
mitotic cell cycle processGO:19030472860.046
negative regulation of catalytic activityGO:00430863350.046
protein catabolic processGO:00301633250.046
establishment or maintenance of cytoskeleton polarityGO:003095230.045
dephosphorylationGO:00163112090.045
generation of neuronsGO:00486991520.040
cell morphogenesisGO:00009022960.040
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.039
positive regulation of transportGO:00510503360.039
regulation of protein localizationGO:00328802960.039
multicellular organismal agingGO:001025930.038
single organism cellular localizationGO:19025803320.038
determination of adult lifespanGO:000834020.038
protein ubiquitinationGO:00165673140.037
neurogenesisGO:00220081690.037
cell activationGO:00017752130.037
cellular response to oxygen containing compoundGO:19017012760.036
mitotic nuclear divisionGO:00070671190.036
post embryonic developmentGO:000979120.036
protein localization to organelleGO:00333652800.035
embryonic epithelial tube formationGO:000183840.035
positive regulation of phosphorylationGO:00423273940.035
positive regulation of protein transportGO:00512221350.035
negative regulation of cellular component organizationGO:00511292350.034
biological adhesionGO:00226103310.034
response to oxygen containing compoundGO:19017003690.033
positive regulation of developmental processGO:00510943140.033
negative regulation of programmed cell deathGO:00430693210.033
oocyte differentiationGO:000999420.033
cellular potassium ion transportGO:0071804600.032
response to organonitrogen compoundGO:00102431560.032
negative regulation of cellular amino acid metabolic processGO:004576320.032
negative regulation of cellular amine metabolic processGO:003323930.031
protein modification by small protein conjugationGO:00324463420.031
maintenance of locationGO:00512351120.031
regulation of mitotic cell cycleGO:00073461890.030
nls bearing protein import into nucleusGO:000660720.030
chemotaxisGO:00069351570.030
immune responseGO:00069553070.029
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.029
negative regulation of cell deathGO:00605483450.029
regulation of locomotionGO:00400123290.028
defense responseGO:00069523150.028
metal ion transportGO:00300012720.028
negative regulation of phosphate metabolic processGO:00459362670.028
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.028
organic anion transportGO:00157111030.028
photoreceptor cell differentiationGO:004653020.027
regulation of cellular component movementGO:00512703340.027
positive regulation of intracellular transportGO:00323881040.027
neuron developmentGO:00486661130.027
ubiquitin dependent protein catabolic processGO:00065112060.027
regulation of establishment of protein localizationGO:00702012420.026
single organism carbohydrate metabolic processGO:00447231930.026
purine nucleoside monophosphate catabolic processGO:00091281580.026
negative regulation of protein metabolic processGO:00512483910.026
regulation of intracellular transportGO:00323861950.026
cellular protein catabolic processGO:00442572610.026
potassium ion transmembrane transportGO:0071805600.026
regulation of cell cycle processGO:00105642660.026
response to biotic stimulusGO:00096072760.026
positive regulation of intracellular protein transportGO:0090316760.025
motor neuron axon guidanceGO:000804520.025
neuron differentiationGO:00301821380.025
cell divisionGO:00513011680.025
cell adhesionGO:00071553250.025
cell cycle phase transitionGO:00447701730.025
regulation of cytoskeleton organizationGO:00514931770.025
regulation of protein catabolic processGO:00421761550.025
positive regulation of cell differentiationGO:00455972110.025
positive regulation of cellular component organizationGO:00511303760.025
growthGO:00400072020.024
modification dependent protein catabolic processGO:00199412090.024
spermatid developmentGO:000728640.023
chemical homeostasisGO:00488783060.023
regulation of intrinsic apoptotic signaling pathwayGO:2001242720.023
vesicle mediated transportGO:00161923710.023
response to growth factorGO:00708482050.023
negative regulation of developmental processGO:00510932470.023
mapk cascadeGO:00001652880.023
neuron projection developmentGO:00311751060.022
regulation of protein processingGO:00706131500.022
positive regulation of protein kinase activityGO:00458601900.022
proteasomal protein catabolic processGO:00104981760.022
regulation of cell cycleGO:00517263930.022
regulation of cell projection organizationGO:00313441070.022
oocyte developmentGO:004859910.021
neural tube formationGO:000184130.021
actin cytoskeleton organizationGO:00300362070.021
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434710.021
primary neural tube formationGO:001402030.021
regulation of cell morphogenesisGO:00226041530.021
negative regulation of intracellular signal transductionGO:19025321830.021
intracellular protein transportGO:00068862700.021
segmentationGO:003528240.021
compound eye developmentGO:004874910.021
apoptotic signaling pathwayGO:00971902680.021
positive regulation of cellular component biogenesisGO:00440891580.020
taxisGO:00423301570.020
epithelium developmentGO:00604292270.020
potassium ion transportGO:0006813620.020
negative regulation of protein modification processGO:00314002000.020
regulation of cell developmentGO:00602841610.020
enzyme linked receptor protein signaling pathwayGO:00071673030.020
negative regulation of cell cycleGO:00457861930.020
negative regulation of multicellular organismal processGO:00512413170.020
nucleocytoplasmic transportGO:00069131760.020
signal transduction by phosphorylationGO:00230142970.020
regulation of cell motilityGO:20001452990.020
nuclear exportGO:0051168690.019
regulation of neurogenesisGO:0050767820.019
regulation of cell migrationGO:00303342890.019
cellular response to hormone stimulusGO:00328701250.019
regulation of mitotic cell cycle phase transitionGO:19019901180.019
system processGO:00030083490.019
negative regulation of apoptotic processGO:00430663160.019
cell part morphogenesisGO:00329901370.019
negative regulation of phosphorus metabolic processGO:00105632670.019
proteolysis involved in cellular protein catabolic processGO:00516032440.019
regulation of protein transportGO:00512232130.019
regulation of cell adhesionGO:00301551660.019
regulation of nucleocytoplasmic transportGO:0046822980.019
nuclear divisionGO:00002801280.019
vasculature developmentGO:00019441810.018
lymphocyte activationGO:00466491330.018
negative regulation of cell proliferationGO:00082852280.018
locomotory behaviorGO:000762610.018
posttranscriptional regulation of gene expressionGO:00106082130.018
stem cell divisionGO:001714520.018
positive regulation of transferase activityGO:00513472270.018
negative regulation of phosphorylationGO:00423261740.018
central nervous system developmentGO:00074171230.018
organelle fissionGO:00482851490.018
positive regulation of kinase activityGO:00336742040.018
peptidyl serine modificationGO:00182091060.017
modification dependent macromolecule catabolic processGO:00436322120.017
response to nitrogen compoundGO:19016981840.017
regulation of kinase activityGO:00435493140.017
rna interferenceGO:001624640.017
innate immune responseGO:00450871780.017
regulation of proteolysisGO:00301622930.017
nucleoside monophosphate metabolic processGO:00091231910.017
cell projection morphogenesisGO:00488581290.017
positive regulation of immune system processGO:00026842830.017
protein oligomerizationGO:00512591730.017
actin filament based processGO:00300292240.017
single organism reproductive processGO:0044702980.017
cellular homeostasisGO:00197251960.016
response to inorganic substanceGO:00100351270.016
regulation of protein complex assemblyGO:00432541470.016
leukocyte activationGO:00453211640.016
protein processingGO:00164852260.016
regenerationGO:003109940.016
nuclear transportGO:00511691790.016
somatic stem cell divisionGO:004810310.016
regulation of neuron differentiationGO:0045664700.016
organonitrogen compound biosynthetic processGO:19015662000.016
nucleus organizationGO:0006997280.016
chromatin organizationGO:00063253510.016
regulation of transferase activityGO:00513383550.016
regulation of growthGO:00400081650.016
cellular response to growth factor stimulusGO:00713631970.016
regulation of peptidyl serine phosphorylationGO:0033135500.016
glycerolipid metabolic processGO:00464861070.016
cellular protein complex assemblyGO:00436231880.016
associative learningGO:000830610.016
tube closureGO:006060630.016
regulation of mrna metabolic processGO:1903311530.016
microtubule organizing center organizationGO:0031023620.015
response to other organismGO:00517072610.015
negative regulation of cell differentiationGO:00455961710.015
nucleoside triphosphate catabolic processGO:00091433940.015
sister chromatid segregationGO:0000819540.015
negative regulation of hydrolase activityGO:00513461820.015
response to external biotic stimulusGO:00432072610.015
negative regulation of protein phosphorylationGO:00019331400.015
single organism cell adhesionGO:00986021790.015
positive regulation of cytoplasmic transportGO:1903651820.015
cell growthGO:00160491600.015
response to bacteriumGO:00096171440.015
rna processingGO:00063962550.015
posttranscriptional gene silencing by rnaGO:0035194250.015
ribonucleoprotein complex localizationGO:007116640.015
cell type specific apoptotic processGO:00972851250.015
wnt signaling pathwayGO:00160551560.015
negative regulation of protein processingGO:00109551420.015
circulatory system developmentGO:00723592620.015
response to lipidGO:00339932060.015
protein localization to nucleusGO:00345041360.015
purine containing compound catabolic processGO:00725234110.014
response to abiotic stimulusGO:00096283360.014
cytokine productionGO:00018162470.014
single organism nuclear importGO:19025931040.014
positive regulation of cell developmentGO:0010720920.014
organophosphate biosynthetic processGO:00904071630.014
neuromuscular junction developmentGO:000752830.014
blood vessel developmentGO:00015681720.014
establishment of protein localization to organelleGO:00725941720.014
striated muscle contractionGO:0006941520.014
nuclear importGO:00511701060.014
negative regulation of proteolysisGO:00458611320.014
protein maturationGO:00516042330.014
hindbrain developmentGO:003090230.014
positive regulation of protein phosphorylationGO:00019343130.014
centrosome organizationGO:0051297580.014
monocarboxylic acid metabolic processGO:00327871850.014
regulation of cytoplasmic transportGO:19036491490.014
positive regulation of purine nucleotide metabolic processGO:19005442270.014
regulation of leukocyte activationGO:00026941150.014
carbohydrate metabolic processGO:00059752070.014
single organismal cell cell adhesionGO:00163371480.014
regulation of meiotic cell cycleGO:005144540.014
protein targetingGO:00066051870.014
cellular response to organonitrogen compoundGO:00714171240.014
positive regulation of protein complex assemblyGO:0031334860.014
regulation of cellular component biogenesisGO:00440872810.014
regulation of actin filament based processGO:00329701410.014
regulation of lymphocyte activationGO:00512491030.014
regulation of cellular protein catabolic processGO:1903362960.014
intrinsic apoptotic signaling pathwayGO:00971931270.014
muscle structure developmentGO:0061061980.014
neural tube closureGO:000184330.014
blastoderm segmentationGO:000735020.014
regulation of growth rateGO:004000910.014
cell morphogenesis involved in differentiationGO:00009041440.014
positive regulation of immune responseGO:00507781590.013
tripartite regional subdivisionGO:000735120.013
negative regulation of mitotic cell cycle phase transitionGO:1901991850.013
nucleoside triphosphate metabolic processGO:00091414220.013
regulation of nervous system developmentGO:0051960880.013
defense response to other organismGO:00985421290.013
purine nucleoside triphosphate catabolic processGO:00091463920.013
calcium ion transmembrane transportGO:0070588760.013
spindle elongationGO:005123140.013
protein polyubiquitinationGO:00002091100.013
ribonucleoprotein complex subunit organizationGO:0071826810.013
carbohydrate derivative biosynthetic processGO:19011372070.013
ras protein signal transductionGO:0007265730.013
reproductive processGO:00224141060.013
mitotic sister chromatid segregationGO:0000070530.013
phospholipid metabolic processGO:0006644990.013
positive regulation of cellular catabolic processGO:00313312840.013
limbic system developmentGO:002176130.013
regulation of apoptotic signaling pathwayGO:20012331750.013
oxidation reduction processGO:00551143960.013
covalent chromatin modificationGO:00165692540.013
cellular response to dna damage stimulusGO:00069743790.013
immune system developmentGO:00025201950.013
nitrogen compound transportGO:00717051910.013
regulation of cellular response to stressGO:00801352440.013
chromosome segregationGO:00070591140.013
regulation of cell cycle phase transitionGO:19019871260.013
cellular macromolecule catabolic processGO:00442653800.013
monovalent inorganic cation transportGO:00156721280.012
brain developmentGO:0007420970.012
positive regulation of dendrite morphogenesisGO:005077530.012
purine nucleotide catabolic processGO:00061954050.012
establishment of rna localizationGO:0051236390.012
glycerophospholipid metabolic processGO:0006650840.012
purine ribonucleoside triphosphate metabolic processGO:00092054110.012
response to oxidative stressGO:00069791210.012
regulation of immune responseGO:00507762010.012
protein import into nucleusGO:00066061040.012
negative regulation of cell cycle phase transitionGO:1901988890.012
regulation of protein serine threonine kinase activityGO:00719001790.012
regulation of wnt signaling pathwayGO:00301111230.012
response to organic cyclic compoundGO:00140702040.012
dna duplex unwindingGO:0032508300.012
establishment or maintenance of cell polarityGO:0007163310.012
negative regulation of cellular catabolic processGO:0031330830.012
intracellular receptor signaling pathwayGO:00305221040.012
regulation of response to external stimulusGO:00321012220.012
ribonucleoprotein complex biogenesisGO:00226131160.012
regulation of proteasomal protein catabolic processGO:0061136870.012
cellular response to lipidGO:00713961270.012
regulation of protein maturationGO:19033171500.012
spindle organizationGO:0007051530.012
cation homeostasisGO:00550801890.012
cellular response to cytokine stimulusGO:00713451810.012
negative regulation of organelle organizationGO:00106391260.012
mitotic cell cycle checkpointGO:0007093680.012
protein dephosphorylationGO:0006470810.012
actin filament organizationGO:00070151280.012
regulation of neuron projection developmentGO:0010975570.012
endomembrane system organizationGO:00102561960.012
response to cytokineGO:00340972320.012
spermatid differentiationGO:004851540.012
cell fate determinationGO:000170930.011
negative regulation of mitotic cell cycleGO:00459301020.011
regulation of protein targetingGO:1903533910.011
positive regulation of catabolic processGO:00098963100.011
meiotic chromosome segregationGO:004513240.011
regulation of cytokine productionGO:00018172320.011
endocytosisGO:00068971590.011
regulation of cell divisionGO:00513021160.011
tissue morphogenesisGO:0048729960.011
cell projection assemblyGO:00300311260.011
ribonucleoside catabolic processGO:00424544060.011
organophosphate catabolic processGO:00464344300.011
anterior posterior axis specification embryoGO:000859520.011
positive regulation of organelle organizationGO:00106381950.011
mitotic spindle organizationGO:0007052270.011
nucleoside phosphate biosynthetic processGO:19012931090.011
negative regulation of catabolic processGO:00098951040.011
cellular carbohydrate metabolic processGO:0044262840.011
positive regulation of cell deathGO:00109422630.011
regulation of cell activationGO:00508651250.011
positive regulation of nf kappab transcription factor activityGO:0051092810.011
positive regulation of locomotionGO:00400171860.011
anion transmembrane transportGO:0098656760.011
ribonucleoside triphosphate metabolic processGO:00091994120.011
protein importGO:00170381300.011
protein autophosphorylationGO:00467771230.011
memoryGO:000761330.011
angiogenesisGO:00015251470.011
regulation of cell growthGO:00015581350.011
purine ribonucleoside monophosphate metabolic processGO:00091671860.011
glycoprotein metabolic processGO:00091001100.011
protein targeting to nucleusGO:00447441040.011
striated muscle adaptationGO:001488840.011
regulation of chromosome organizationGO:00330441030.011
reactive oxygen species biosynthetic processGO:190340940.010
cellular response to nitrogen compoundGO:19016991440.010
long term memoryGO:000761620.010
response to fungusGO:000962040.010
nucleotide biosynthetic processGO:00091651090.010
hippocampus developmentGO:002176610.010
negative regulation of cell cycle processGO:00109481210.010
regulation of protein modification by small protein conjugation or removalGO:19033201070.010
epithelial cell proliferationGO:00506731280.010
maturation of ssu rrnaGO:003049030.010
convergent extensionGO:006002610.010
chromatin modificationGO:00165682980.010
regulation of dephosphorylationGO:0035303960.010
cellular component disassemblyGO:0022411920.010
small molecule catabolic processGO:0044282920.010
peptidyl tyrosine phosphorylationGO:00181081700.010
tube morphogenesisGO:0035239950.010
syncytium formation by plasma membrane fusionGO:000076820.010
dna replicationGO:00062601160.010
lipid localizationGO:00108761060.010

SACS disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
musculoskeletal system diseaseDOID:172230.027
muscular diseaseDOID:00800001140.014
nervous system diseaseDOID:8634310.014
sensory system diseaseDOID:00501552030.014
organ system cancerDOID:00506861640.013
cancerDOID:1621670.013
disease of cellular proliferationDOID:145661740.013
myopathyDOID:4231040.012
muscle tissue diseaseDOID:661130.012
neuropathyDOID:870520.010