Homo sapiens

0 known processes

PHLPP2

PH domain and leucine rich repeat protein phosphatase 2

(Aliases: PHLPPL,KIAA0931)

PHLPP2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
protein modification by small protein removalGO:0070646920.618
protein deubiquitinationGO:0016579790.517
fear responseGO:004259600.155
cellular protein complex disassemblyGO:0043624360.138
multicellular organismal response to stressGO:003355510.136
behavioral defense responseGO:000220900.105
post embryonic developmentGO:000979120.087
behavioral response to ethanolGO:004814920.081
amine metabolic processGO:0009308440.077
cellular amine metabolic processGO:0044106410.075
multicellular organismal agingGO:001025930.071
cellular ketone metabolic processGO:0042180800.070
regulation of cellular ketone metabolic processGO:0010565500.070
cellular homeostasisGO:00197251960.068
regulation of cellular amine metabolic processGO:0033238110.067
regulation of cellular amino acid metabolic processGO:000652160.067
positive regulation of cell proliferationGO:00082843010.066
regulation of homeostatic processGO:00328441210.062
establishment or maintenance of epithelial cell apical basal polarityGO:004519710.059
segmentationGO:003528240.056
cellular amino acid metabolic processGO:00065201160.054
cellular component disassemblyGO:0022411920.053
vesicle mediated transportGO:00161923710.049
female gamete generationGO:000729220.046
organophosphate catabolic processGO:00464344300.046
glycosyl compound catabolic processGO:19016584130.045
dna repairGO:00062811980.044
negative regulation of cellular amino acid metabolic processGO:004576320.043
blastoderm segmentationGO:000735020.042
nucleoside phosphate catabolic processGO:19012924120.041
cellular response to dna damage stimulusGO:00069743790.041
macromolecular complex disassemblyGO:0032984600.041
negative regulation of cellular amine metabolic processGO:003323930.041
determination of adult lifespanGO:000834020.040
oogenesisGO:004847720.039
establishment or maintenance of bipolar cell polarityGO:006124520.039
dephosphorylationGO:00163112090.038
Rat Fly
protein dephosphorylationGO:0006470810.038
Rat Fly
anterior posterior axis specificationGO:000994820.038
negative regulation of protein metabolic processGO:00512483910.037
protein catabolic processGO:00301633250.037
oocyte differentiationGO:000999420.036
mitotic cell cycleGO:00002783260.035
epithelium developmentGO:00604292270.033
negative regulation of phosphorus metabolic processGO:00105632670.033
cytoplasmic transportGO:00164823790.032
cellular protein catabolic processGO:00442572610.032
positive regulation of catabolic processGO:00098963100.032
regulation of cell migrationGO:00303342890.032
oocyte developmentGO:004859910.031
anterior posterior axis specification embryoGO:000859520.031
modification dependent protein catabolic processGO:00199412090.031
ubiquitin dependent protein catabolic processGO:00065112060.031
double strand break repairGO:00063021010.031
defense responseGO:00069523150.030
locomotory behaviorGO:000762610.030
response to oxygen containing compoundGO:19017003690.030
protein complex disassemblyGO:0043241520.030
purine ribonucleotide catabolic processGO:00091544040.029
positive regulation of cellular amino acid metabolic processGO:004576430.029
lipid metabolic processGO:00066293810.029
cell adhesionGO:00071553250.029
positive regulation of cellular amine metabolic processGO:003324070.029
single organism membrane organizationGO:00448022680.028
membrane organizationGO:00610242920.028
cellular macromolecule catabolic processGO:00442653800.028
tripartite regional subdivisionGO:000735120.028
negative regulation of catalytic activityGO:00430863350.027
regulation of cellular component movementGO:00512703340.027
endomembrane system organizationGO:00102561960.027
negative regulation of phosphate metabolic processGO:00459362670.027
cellular macromolecular complex assemblyGO:00346223240.027
regulation of membrane potentialGO:0042391950.027
negative regulation of protein modification processGO:00314002000.027
modification dependent macromolecule catabolic processGO:00436322120.027
cation transportGO:00068123310.027
positive regulation of cellular component organizationGO:00511303760.027
purine containing compound catabolic processGO:00725234110.026
nucleoside triphosphate metabolic processGO:00091414220.026
endosomal transportGO:00161971290.026
purine ribonucleoside triphosphate metabolic processGO:00092054110.026
single organism cell adhesionGO:00986021790.026
proteolysis involved in cellular protein catabolic processGO:00516032440.025
regulation of protein modification by small protein conjugation or removalGO:19033201070.025
intracellular protein transportGO:00068862700.025
negative regulation of intracellular signal transductionGO:19025321830.025
regulation of cell cycle processGO:00105642660.025
chemical homeostasisGO:00488783060.025
cell developmentGO:00484683280.025
regulation of cell cycleGO:00517263930.025
epithelial cell differentiationGO:00308551410.025
nervous system developmentGO:00073992930.025
Rat
regulation of protein kinase activityGO:00458592890.025
regulation of cell motilityGO:20001452990.024
skin developmentGO:0043588760.024
purine nucleoside catabolic processGO:00061523980.023
neuromuscular junction developmentGO:000752830.023
regulation of cellular component biogenesisGO:00440872810.023
proteasomal protein catabolic processGO:00104981760.023
dna replicationGO:00062601160.023
regulation of locomotionGO:00400123290.023
covalent chromatin modificationGO:00165692540.023
peptidyl tyrosine phosphorylationGO:00181081700.022
microtubule based processGO:00070172100.022
system processGO:00030083490.022
microtubule cytoskeleton organizationGO:00002261760.022
mitotic cell cycle processGO:19030472860.022
negative regulation of phosphorylationGO:00423261740.022
purine ribonucleoside metabolic processGO:00461284370.021
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.021
single organism cellular localizationGO:19025803320.021
regulation of cell adhesionGO:00301551660.020
neurological system processGO:00508771630.020
positive regulation of nucleotide metabolic processGO:00459812300.020
chromatin modificationGO:00165682980.020
posttranscriptional regulation of gene expressionGO:00106082130.020
morphogenesis of embryonic epitheliumGO:001633140.020
cellular lipid metabolic processGO:00442553030.020
actin filament based processGO:00300292240.020
transmembrane transportGO:00550853990.020
signal transduction by phosphorylationGO:00230142970.020
negative regulation of cellular component organizationGO:00511292350.020
cellular protein complex assemblyGO:00436231880.020
secretionGO:00469032540.020
apoptotic signaling pathwayGO:00971902680.020
metal ion transportGO:00300012720.019
negative regulation of cellular protein metabolic processGO:00322693530.019
peptidyl tyrosine modificationGO:00182121700.019
cell cycle phase transitionGO:00447701730.019
cytokinesisGO:0000910960.019
cell divisionGO:00513011680.019
response to alcoholGO:0097305640.019
behavioral fear responseGO:000166200.019
protein modification by small protein conjugationGO:00324463420.019
cell morphogenesisGO:00009022960.019
behaviorGO:00076101120.018
nucleotide catabolic processGO:00091664080.018
nucleoside triphosphate catabolic processGO:00091433940.018
purine nucleoside triphosphate catabolic processGO:00091463920.018
regulation of transferase activityGO:00513383550.018
positive regulation of gtpase activityGO:00435471660.018
positive regulation of transportGO:00510503360.018
negative regulation of apoptotic processGO:00430663160.018
ras protein signal transductionGO:0007265730.018
regulation of mitotic cell cycleGO:00073461890.018
regulation of cellular response to stressGO:00801352440.018
regulation of dna metabolic processGO:00510521530.018
positive regulation of programmed cell deathGO:00430682490.018
regulation of purine nucleotide metabolic processGO:19005422640.018
single organismal cell cell adhesionGO:00163371480.018
regulation of nucleoside metabolic processGO:00091182090.018
actin cytoskeleton organizationGO:00300362070.018
ion homeostasisGO:00508012300.018
histone modificationGO:00165702510.018
organelle assemblyGO:00709251760.018
purine nucleoside triphosphate metabolic processGO:00091444120.017
immune responseGO:00069553070.017
protein maturationGO:00516042330.017
striated muscle myosin thick filament assemblyGO:007168820.017
tube developmentGO:00352951250.017
endocytosisGO:00068971590.017
regulation of mitosisGO:0007088630.017
endosome to lysosome transportGO:0008333210.017
myosin filament assemblyGO:003103420.017
regenerationGO:003109940.017
negative regulation of cell deathGO:00605483450.017
regulation of cytoskeleton organizationGO:00514931770.017
regulation of protein ubiquitinationGO:0031396950.017
mitotic nuclear divisionGO:00070671190.017
response to abiotic stimulusGO:00096283360.017
carbohydrate derivative biosynthetic processGO:19011372070.017
organelle fissionGO:00482851490.017
cellular component morphogenesisGO:00329893140.016
spermatid differentiationGO:004851540.016
protein processingGO:00164852260.016
cell projection assemblyGO:00300311260.016
regulation of kinase activityGO:00435493140.016
mitotic cell cycle phase transitionGO:00447721620.016
organonitrogen compound biosynthetic processGO:19015662000.016
spermatid developmentGO:000728640.016
positive regulation of phosphorylationGO:00423273940.016
regulation of epithelial cell proliferationGO:00506781130.016
positive regulation of cellular component biogenesisGO:00440891580.016
gtp catabolic processGO:00061842370.016
memoryGO:000761330.016
nucleoside catabolic processGO:00091644080.016
protein depolymerizationGO:0051261300.016
regulation of cell divisionGO:00513021160.016
biological adhesionGO:00226103310.016
inorganic ion transmembrane transportGO:00986602310.016
nuclear divisionGO:00002801280.016
guanosine containing compound catabolic processGO:19010692390.016
regulation of protein localizationGO:00328802960.016
epithelial cell proliferationGO:00506731280.016
positive regulation of epithelial cell proliferationGO:0050679650.015
negative regulation of programmed cell deathGO:00430693210.015
regulation of cell cell adhesionGO:0022407570.015
regulation of peptidyl tyrosine phosphorylationGO:00507301080.015
positive regulation of organelle organizationGO:00106381950.015
plasma membrane organizationGO:00070091150.015
regulation of proteolysisGO:00301622930.015
regulation of vesicle mediated transportGO:00606271300.015
negative regulation of protein phosphorylationGO:00019331400.015
protein localization to plasma membraneGO:0072659930.015
ion transmembrane transportGO:00342203380.015
adult locomotory behaviorGO:000834410.015
associative learningGO:000830610.015
cation transmembrane transportGO:00986552380.015
myosin filament organizationGO:003103320.015
regulation of ras protein signal transductionGO:00465781550.015
regulation of anatomical structure morphogenesisGO:00226032860.014
positive regulation of nucleoside metabolic processGO:00459791860.014
ameboidal type cell migrationGO:00016671350.014
negative regulation of phosphatidylinositol 3 kinase signalingGO:001406740.014
sensory perceptionGO:00076001030.014
response to radiationGO:00093141510.014
protein ubiquitinationGO:00165673140.014
regulation of immune responseGO:00507762010.014
regulation of purine nucleotide catabolic processGO:00331212050.014
carbohydrate metabolic processGO:00059752070.014
regulation of mapk cascadeGO:00434082620.014
actin filament organizationGO:00070151280.014
cellular response to oxygen containing compoundGO:19017012760.014
ribonucleoside triphosphate metabolic processGO:00091994120.014
regulation of apoptotic signaling pathwayGO:20012331750.014
negative regulation of multicellular organismal processGO:00512413170.014
cellular chemical homeostasisGO:00550821800.014
cellular component assembly involved in morphogenesisGO:0010927730.014
regulation of nucleotide metabolic processGO:00061402690.014
reactive oxygen species biosynthetic processGO:190340940.014
positive regulation of immune system processGO:00026842830.014
negative regulation of protein kinase b signalingGO:0051898170.014
peripheral nervous system developmentGO:000742220.014
negative regulation of transportGO:00510511760.014
divalent metal ion transportGO:00708381520.014
rhythmic behaviorGO:000762220.014
nitrogen compound transportGO:00717051910.014
gtp metabolic processGO:00460392390.014
regulation of cell growthGO:00015581350.014
negative regulation of cell adhesionGO:0007162640.013
carboxylic acid biosynthetic processGO:0046394970.013
cell projection organizationGO:00300302520.013
sister chromatid segregationGO:0000819540.013
mitotic sister chromatid segregationGO:0000070530.013
regulation of chromosome organizationGO:00330441030.013
protein localization to membraneGO:00726571600.013
neurotransmitter secretionGO:000726940.013
positive regulation of apoptotic processGO:00430652460.013
cation homeostasisGO:00550801890.013
negative regulation of cell proliferationGO:00082852280.013
negative regulation of dna metabolic processGO:0051053570.013
mapk cascadeGO:00001652880.013
cellular response to abiotic stimulusGO:00712141170.013
mitotic sister chromatid separationGO:0051306180.013
enzyme linked receptor protein signaling pathwayGO:00071673030.013
regulation of protein maturationGO:19033171500.013
cell projection morphogenesisGO:00488581290.013
nerve developmentGO:002167540.013
notch signaling pathwayGO:0007219310.013
reproductive processGO:00224141060.013
compound eye developmentGO:004874910.013
motor neuron axon guidanceGO:000804520.013
establishment of protein localization to membraneGO:00901501210.013
positive regulation of purine nucleotide catabolic processGO:00331231850.012
positive regulation of developmental processGO:00510943140.012
inorganic cation transmembrane transportGO:00986621940.012
regulation of protein kinase b signalingGO:0051896610.012
regulation of secretionGO:00510461940.012
ribonucleoside catabolic processGO:00424544060.012
positive regulation of protein kinase activityGO:00458601900.012
small gtpase mediated signal transductionGO:0007264780.012
response to growth factorGO:00708482050.012
anion transportGO:00068201610.012
forebrain developmentGO:0030900260.012
Rat
glial cell migrationGO:000834740.012
hippocampus developmentGO:002176610.012
Rat
limbic system developmentGO:002176130.012
Rat
metaphase anaphase transition of cell cycleGO:0044784210.012
negative regulation of proteolysisGO:00458611320.012
oxidation reduction processGO:00551143960.012
positive regulation of cell deathGO:00109422630.012
cellular response to endogenous stimulusGO:00714953360.012
negative regulation of cell cycleGO:00457861930.012
cellular cation homeostasisGO:00300031630.012
positive regulation of cell migrationGO:00303351720.012
regulation of neural precursor cell proliferationGO:200017740.012
purine nucleotide catabolic processGO:00061954050.012
protein localization to organelleGO:00333652800.012
cellular ion homeostasisGO:00068731680.012
response to ethanolGO:0045471110.012
organelle localizationGO:0051640840.012
chromosome segregationGO:00070591140.012
jak stat cascadeGO:0007259460.012
dna recombinationGO:0006310770.012
positive regulation of cell differentiationGO:00455972110.011
protein kinase c signalingGO:0070528170.011
negative regulation of organelle organizationGO:00106391260.011
rho protein signal transductionGO:0007266260.011
cellular response to growth factor stimulusGO:00713631970.011
generation of neuronsGO:00486991520.011
matingGO:000761810.011
divalent inorganic cation transportGO:00725111580.011
regulation of intracellular transportGO:00323861950.011
protein oligomerizationGO:00512591730.011
establishment or maintenance of apical basal cell polarityGO:003508820.011
neurogenesisGO:00220081690.011
response to light stimulusGO:0009416870.011
growthGO:00400072020.011
single organism carbohydrate metabolic processGO:00447231930.011
taxisGO:00423301570.011
monocarboxylic acid metabolic processGO:00327871850.011
chromosome separationGO:0051304230.011
regulation of cell morphogenesisGO:00226041530.011
positive regulation of cellular catabolic processGO:00313312840.011
regulation of protein processingGO:00706131500.011
regulation of reactive oxygen species biosynthetic processGO:190342630.011
positive regulation of cytoskeleton organizationGO:0051495830.011
purine ribonucleoside monophosphate metabolic processGO:00091671860.011
intrinsic apoptotic signaling pathwayGO:00971931270.011
response to fungusGO:000962040.011
chromatin organizationGO:00063253510.011
reactive oxygen species metabolic processGO:0072593750.011
cell cell junction organizationGO:0045216690.011
sensory perception of smellGO:000760820.011
protein monoubiquitinationGO:0006513390.011
positive regulation of cellular component movementGO:00512721810.011
ribonucleoside monophosphate metabolic processGO:00091611870.011
rna interferenceGO:001624640.011
response to cytokineGO:00340972320.011
regulation of establishment of protein localizationGO:00702012420.011
response to lipidGO:00339932060.011
organophosphate biosynthetic processGO:00904071630.011
blood vessel developmentGO:00015681720.011
positive regulation of hydrolase activityGO:00513453310.011
regulation of dna replicationGO:0006275680.011
positive regulation of i kappab kinase nf kappab signalingGO:00431231320.011
blood vessel morphogenesisGO:00485141620.011
lysosomal transportGO:0007041330.011
negative regulation of transferase activityGO:00513481240.011
purine nucleoside monophosphate metabolic processGO:00091261860.011
i kappab kinase nf kappab signalingGO:00072491660.011
meiosis iGO:000712740.011
regulation of response to dna damage stimulusGO:2001020940.011
response to nitrogen compoundGO:19016981840.011
photoreceptor cell differentiationGO:004653020.011
metal ion homeostasisGO:00550651690.010
cellular metal ion homeostasisGO:00068751460.010
innate immune responseGO:00450871780.010
regulation of cysteine type endopeptidase activityGO:20001161270.010
positive regulation of synaptic transmissionGO:005080640.010
regulation of ion transportGO:00432691890.010
regulation of gtp catabolic processGO:00331241800.010
regulation of nucleotide catabolic processGO:00308112050.010
alcohol metabolic processGO:00060661140.010
negative regulation of hydrolase activityGO:00513461820.010
regulation of endopeptidase activityGO:00525481700.010
cell fate determinationGO:000170930.010
cell part morphogenesisGO:00329901370.010
circadian behaviorGO:004851220.010
regulation of protein transportGO:00512232130.010
mitochondrion organizationGO:00070051560.010
cerebellum developmentGO:002154920.010
regulation of lymphocyte migrationGO:2000401220.010
regulation of protein catabolic processGO:00421761550.010
negative regulation of protein processingGO:00109551420.010
positive regulation of endocytosisGO:0045807420.010
interspecies interaction between organismsGO:00444191560.010
phospholipid metabolic processGO:0006644990.010
leukocyte migrationGO:00509001070.010
regulation of tyrosine phosphorylation of stat3 proteinGO:0042516180.010
reactive nitrogen species metabolic processGO:200105730.010
hippo signalingGO:0035329200.010
maintenance of locationGO:00512351120.010
regulation of i kappab kinase nf kappab signalingGO:00431221620.010
sensory perception of painGO:001923340.010
regulation of peptidase activityGO:00525471800.010
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic processGO:0031145250.010
lipid biosynthetic processGO:00086101770.010

PHLPP2 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:8634310.051
sensory system diseaseDOID:00501552030.051
nonsyndromic deafnessDOID:0050563500.023
auditory system diseaseDOID:2742530.023
disease of metabolismDOID:00146672950.023
central nervous system diseaseDOID:3311860.021
inherited metabolic disorderDOID:6552420.015
autosomal recessive nonsyndromic deafnessDOID:0050565330.015
disease of cellular proliferationDOID:145661740.014
cancerDOID:1621670.014
organ system cancerDOID:00506861640.014
musculoskeletal system diseaseDOID:172230.014
eye and adnexa diseaseDOID:14921500.013
eye diseaseDOID:56141490.013
neurodegenerative diseaseDOID:12891020.010