Homo sapiens

0 known processes

HADHA

hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit

(Aliases: ECHA,LCHAD,HADH,MGC1728,GBP,TP-ALPHA,LCEH,MTPA)

HADHA biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
oxidation reduction processGO:00551143960.951
Mouse Fly
carboxylic acid catabolic processGO:0046395710.915
Mouse Fly
lipid oxidationGO:0034440330.838
Mouse Fly
fatty acid metabolic processGO:00066311150.832
Mouse Fly
organic acid catabolic processGO:0016054710.706
Mouse Fly
determination of adult lifespanGO:000834020.690
Fly
multicellular organismal agingGO:001025930.669
Fly
monocarboxylic acid catabolic processGO:0072329370.626
Mouse Fly
cellular lipid metabolic processGO:00442553030.617
Mouse Fly
lipid catabolic processGO:0016042840.506
Mouse Fly
rab protein signal transductionGO:003248240.401
small molecule catabolic processGO:0044282920.381
Mouse Fly
cellular lipid catabolic processGO:0044242650.377
Mouse Fly
fatty acid oxidationGO:0019395310.350
Mouse Fly
nucleoside monophosphate metabolic processGO:00091231910.346
lipid metabolic processGO:00066293810.338
Mouse Fly
monocarboxylic acid metabolic processGO:00327871850.329
Mouse Fly
energy derivation by oxidation of organic compoundsGO:0015980430.322
ribonucleoside monophosphate metabolic processGO:00091611870.315
purine nucleoside triphosphate metabolic processGO:00091444120.302
purine nucleoside monophosphate metabolic processGO:00091261860.296
mitochondrion organizationGO:00070051560.285
tricarboxylic acid metabolic processGO:007235040.279
post embryonic developmentGO:000979120.241
Worm
lipid modificationGO:0030258840.232
Mouse Fly
aerobic respirationGO:000906070.228
fatty acid catabolic processGO:0009062290.204
Mouse Fly
cellular respirationGO:0045333210.190
protein oligomerizationGO:00512591730.187
purine ribonucleoside monophosphate metabolic processGO:00091671860.181
nucleoside triphosphate metabolic processGO:00091414220.181
purine ribonucleoside metabolic processGO:00461284370.180
purine ribonucleoside triphosphate metabolic processGO:00092054110.150
agingGO:0007568660.134
Fly
atp metabolic processGO:00460341760.115
generation of precursor metabolites and energyGO:0006091680.113
purine ribonucleoside monophosphate catabolic processGO:00091691580.106
ribonucleoside triphosphate metabolic processGO:00091994120.097
membrane organizationGO:00610242920.089
ribose phosphate biosynthetic processGO:0046390820.080
cellular amino acid metabolic processGO:00065201160.079
purine containing compound catabolic processGO:00725234110.079
purine ribonucleotide biosynthetic processGO:0009152790.076
protein homooligomerizationGO:00512601000.075
negative regulation of cell deathGO:00605483450.074
locomotory behaviorGO:000762610.073
system processGO:00030083490.072
purine ribonucleoside triphosphate catabolic processGO:00092073910.070
regulation of purine nucleotide catabolic processGO:00331212050.068
regulation of purine nucleotide metabolic processGO:19005422640.068
nadh dehydrogenase complex assemblyGO:0010257160.068
vesicle mediated transportGO:00161923710.066
Worm
cellular cation homeostasisGO:00300031630.066
organonitrogen compound biosynthetic processGO:19015662000.065
cellular ketone metabolic processGO:0042180800.065
nucleoside phosphate catabolic processGO:19012924120.065
regulation of atpase activityGO:0043462250.064
organophosphate catabolic processGO:00464344300.064
fatty acid beta oxidationGO:0006635220.062
Mouse Fly
cation transmembrane transportGO:00986552380.061
tricarboxylic acid cycleGO:000609940.060
regulation of cellular ketone metabolic processGO:0010565500.058
dicarboxylic acid biosynthetic processGO:004365040.057
purine nucleoside monophosphate catabolic processGO:00091281580.056
regulation of cellular amino acid metabolic processGO:000652160.055
carbohydrate derivative biosynthetic processGO:19011372070.055
positive regulation of cellular amino acid metabolic processGO:004576430.054
response to external biotic stimulusGO:00432072610.054
Zebrafish
transmembrane transportGO:00550853990.054
nucleoside catabolic processGO:00091644080.053
nitrogen compound transportGO:00717051910.053
negative regulation of transportGO:00510511760.053
female gamete generationGO:000729220.053
purine ribonucleoside biosynthetic processGO:0046129230.050
organic hydroxy compound metabolic processGO:19016151470.049
ribonucleoside triphosphate catabolic processGO:00092033910.049
regulation of nucleotide catabolic processGO:00308112050.049
purine nucleotide catabolic processGO:00061954050.048
cellular protein complex assemblyGO:00436231880.048
guanosine containing compound metabolic processGO:19010682440.048
anion transportGO:00068201610.048
embryo developmentGO:00097901230.047
Worm
positive regulation of developmental processGO:00510943140.047
negative regulation of apoptotic processGO:00430663160.047
cellular amine metabolic processGO:0044106410.046
purine nucleoside triphosphate catabolic processGO:00091463920.046
cellular ion homeostasisGO:00068731680.042
cellular homeostasisGO:00197251960.042
ion homeostasisGO:00508012300.041
amine metabolic processGO:0009308440.041
purine ribonucleotide catabolic processGO:00091544040.040
ras protein signal transductionGO:0007265730.040
regulation of nucleotide metabolic processGO:00061402690.040
protein processingGO:00164852260.039
ossificationGO:00015031210.038
epithelium developmentGO:00604292270.038
single organism membrane organizationGO:00448022680.038
nucleoside triphosphate catabolic processGO:00091433940.037
cell developmentGO:00484683280.037
positive regulation of apoptotic processGO:00430652460.036
oogenesisGO:004847720.036
nucleotide catabolic processGO:00091664080.036
growthGO:00400072020.035
regulation of cellular amine metabolic processGO:0033238110.035
secretion by cellGO:00329402260.035
cellular chemical homeostasisGO:00550821800.035
positive regulation of programmed cell deathGO:00430682490.035
response to abiotic stimulusGO:00096283360.034
regulation of secretionGO:00510461940.034
cation homeostasisGO:00550801890.034
negative regulation of catalytic activityGO:00430863350.034
protein maturationGO:00516042330.033
ribonucleoside catabolic processGO:00424544060.033
immune responseGO:00069553070.033
endosomal transportGO:00161971290.033
dicarboxylic acid metabolic processGO:0043648290.032
citrate metabolic processGO:000610120.032
organophosphate biosynthetic processGO:00904071630.032
cellular component morphogenesisGO:00329893140.032
protein tetramerizationGO:0051262470.032
regulation of nucleoside metabolic processGO:00091182090.032
intracellular protein transportGO:00068862700.031
ribonucleotide catabolic processGO:00092614050.031
single organism membrane fusionGO:0044801370.031
regulation of mitochondrion organizationGO:0010821540.031
ribonucleoside monophosphate catabolic processGO:00091581580.031
positive regulation of catabolic processGO:00098963100.030
epithelial cell differentiationGO:00308551410.030
coenzyme metabolic processGO:0006732650.030
positive regulation of purine nucleotide metabolic processGO:19005442270.030
negative regulation of protein metabolic processGO:00512483910.030
inorganic anion transmembrane transportGO:0098661470.030
cellular response to oxidative stressGO:0034599850.030
regulation of atp catabolic processGO:1903289250.029
nucleoside phosphate biosynthetic processGO:19012931090.029
response to oxygen containing compoundGO:19017003690.029
Mouse
apoptotic signaling pathwayGO:00971902680.029
protein localization to organelleGO:00333652800.029
purine ribonucleoside catabolic processGO:00461303980.029
neuroblast proliferationGO:000740540.029
carboxylic acid biosynthetic processGO:0046394970.028
regulation of atp metabolic processGO:1903578290.028
ion transmembrane transportGO:00342203380.028
positive regulation of cell differentiationGO:00455972110.028
cytoplasmic transportGO:00164823790.027
primary alcohol metabolic processGO:0034308170.027
excretionGO:000758890.027
hemoglobin metabolic processGO:002002730.027
response to inorganic substanceGO:00100351270.027
regulation of oxidoreductase activityGO:0051341430.026
regulation of mitochondrial membrane permeability involved in apoptotic processGO:1902108180.026
nucleotide biosynthetic processGO:00091651090.026
negative regulation of cell proliferationGO:00082852280.025
inorganic ion transmembrane transportGO:00986602310.025
mitochondrial transportGO:0006839600.025
regulation of sequence specific dna binding transcription factor activityGO:00510902110.025
cellular amino acid catabolic processGO:0009063310.025
regulation of rab gtpase activityGO:0032313390.025
negative regulation of cellular component organizationGO:00511292350.024
mitochondrial respiratory chain complex i biogenesisGO:0097031160.024
purine nucleotide biosynthetic processGO:0006164840.024
regulation of neural precursor cell proliferationGO:200017740.024
negative regulation of atpase activityGO:003278050.024
nucleoside triphosphate biosynthetic processGO:0009142200.023
purine containing compound biosynthetic processGO:0072522880.023
establishment of protein localization to organelleGO:00725941720.023
positive regulation of nucleotide metabolic processGO:00459812300.023
response to metal ionGO:0010038840.023
reactive oxygen species metabolic processGO:0072593750.022
purine nucleoside catabolic processGO:00061523980.022
negative regulation of oxidoreductase activityGO:0051354170.022
defense response to other organismGO:00985421290.022
response to decreased oxygen levelsGO:0036293960.022
secretionGO:00469032540.022
positive regulation of sequence specific dna binding transcription factor activityGO:00510911310.022
mitochondrial membrane organizationGO:0007006400.022
protein localization to membraneGO:00726571600.021
alcohol metabolic processGO:00060661140.021
cellular amide metabolic processGO:0043603690.021
matingGO:000761810.021
peptide transportGO:0015833740.021
receptor mediated endocytosisGO:0006898840.021
Worm
organic acid biosynthetic processGO:0016053970.021
cell morphogenesisGO:00009022960.021
negative regulation of apoptotic signaling pathwayGO:2001234970.021
inorganic anion transportGO:0015698600.020
negative regulation of programmed cell deathGO:00430693210.020
establishment of protein localization to membraneGO:00901501210.020
acylglycerol metabolic processGO:0006639270.020
cellular macromolecular complex assemblyGO:00346223240.019
response to drugGO:0042493810.019
ribonucleotide biosynthetic processGO:0009260810.019
response to peptideGO:1901652650.019
Mouse
positive regulation of nucleotide catabolic processGO:00308131850.019
regulation of rab protein signal transductionGO:0032483390.018
protein targeting to membraneGO:0006612420.018
negative regulation of secretion by cellGO:1903531520.018
regulation of cell differentiationGO:00455953930.018
cellular response to oxygen containing compoundGO:19017012760.018
negative regulation of multicellular organismal processGO:00512413170.018
positive regulation of hydrolase activityGO:00513453310.018
positive regulation of cellular amine metabolic processGO:003324070.017
positive regulation of secretion by cellGO:19035321080.017
nervous system developmentGO:00073992930.017
regulation of mitochondrial membrane permeabilityGO:0046902250.017
negative regulation of cellular catabolic processGO:0031330830.017
isoprenoid metabolic processGO:0006720390.017
neuromuscular junction developmentGO:000752830.017
negative regulation of protein processingGO:00109551420.017
neuron projection developmentGO:00311751060.017
translationGO:00064121320.017
golgi vesicle transportGO:0048193800.017
negative regulation of transferase activityGO:00513481240.016
generation of neuronsGO:00486991520.016
cation transportGO:00068123310.016
tube developmentGO:00352951250.016
response to oxidative stressGO:00069791210.016
phosphate ion transmembrane transportGO:003543540.016
organelle assemblyGO:00709251760.016
mitochondrial respiratory chain complex i assemblyGO:0032981160.016
cellular response to reactive oxygen speciesGO:0034614500.016
endocytosisGO:00068971590.016
Worm
autophagyGO:0006914880.016
negative regulation of nucleotide catabolic processGO:0030812160.016
mitochondrial atp synthesis coupled electron transportGO:004277540.016
cell part morphogenesisGO:00329901370.016
positive regulation of transportGO:00510503360.016
cellular metal ion homeostasisGO:00068751460.016
cell morphogenesis involved in differentiationGO:00009041440.015
regenerationGO:003109940.015
positive regulation of rab gtpase activityGO:0032851390.015
regulation of proteolysisGO:00301622930.015
positive regulation of purine nucleotide catabolic processGO:00331231850.015
actin mediated cell contractionGO:0070252120.015
positive regulation of ras gtpase activityGO:00323201170.015
negative regulation of cellular amino acid metabolic processGO:004576320.015
regulation of growthGO:00400081650.015
regulation of transferase activityGO:00513383550.015
reproductive processGO:00224141060.015
metal ion homeostasisGO:00550651690.015
regulation of membrane permeabilityGO:0090559250.015
negative regulation of cellular amine metabolic processGO:003323930.014
regulation of stress activated protein kinase signaling cascadeGO:0070302850.014
positive regulation of cell deathGO:00109422630.014
organic anion transportGO:00157111030.014
chemical homeostasisGO:00488783060.014
negative regulation of hydrolase activityGO:00513461820.014
small molecule biosynthetic processGO:00442831570.014
single organism cellular localizationGO:19025803320.014
nadh metabolic processGO:000673410.014
defense response to bacteriumGO:0042742630.014
endomembrane system organizationGO:00102561960.014
icosanoid metabolic processGO:0006690350.014
regulation of gtpase activityGO:00430871800.014
negative regulation of phosphorus metabolic processGO:00105632670.014
anatomical structure formation involved in morphogenesisGO:00486462840.014
regulation of apoptotic signaling pathwayGO:20012331750.014
regulation of protein maturationGO:19033171500.014
regulation of cellular response to stressGO:00801352440.014
positive regulation of mitochondrial membrane permeabilityGO:0035794170.014
positive regulation of gtpase activityGO:00435471660.014
regulation of secretion by cellGO:19035301770.014
negative regulation of proteolysisGO:00458611320.014
regulation of anatomical structure morphogenesisGO:00226032860.014
apoptotic mitochondrial changesGO:0008637570.014
nucleoside monophosphate catabolic processGO:00091251590.014
negative regulation of intracellular transportGO:0032387600.014
negative regulation of stem cell proliferationGO:200064730.014
peripheral nervous system developmentGO:000742220.014
response to nitrogen compoundGO:19016981840.014
Mouse
purine nucleoside monophosphate biosynthetic processGO:0009127160.014
glycosyl compound catabolic processGO:19016584130.014
reproductive structure developmentGO:0048608550.013
regulation of necrotic cell deathGO:001093990.013
single organism reproductive processGO:0044702980.013
regulation of intracellular transportGO:00323861950.013
cytokine productionGO:00018162470.013
regulation of peptidase activityGO:00525471800.013
tissue morphogenesisGO:0048729960.013
glycosyl compound biosynthetic processGO:1901659270.013
atp catabolic processGO:00062001570.013
regulation of endopeptidase activityGO:00525481700.013
regulation of ras gtpase activityGO:00323181280.013
spermatid differentiationGO:004851540.013
cellular response to oxygen levelsGO:0071453550.013
protein catabolic processGO:00301633250.013
cellular response to endogenous stimulusGO:00714953360.013
positive regulation of cellular catabolic processGO:00313312840.013
guanosine containing compound catabolic processGO:19010692390.013
memoryGO:000761330.013
atp synthesis coupled electron transportGO:004277340.013
cofactor metabolic processGO:0051186870.013
response to salt stressGO:000965130.013
defense responseGO:00069523150.013
lung epithelial cell differentiationGO:006048710.012
protein modification by small protein conjugationGO:00324463420.012
terpenoid metabolic processGO:0006721270.012
monovalent inorganic cation transportGO:00156721280.012
leukotriene metabolic processGO:0006691100.012
regulation of hormone levelsGO:00108171250.012
cell projection morphogenesisGO:00488581290.012
morphogenesis of embryonic epitheliumGO:001633140.012
protein ubiquitinationGO:00165673140.012
response to hypoxiaGO:0001666960.012
positive regulation of nucleoside metabolic processGO:00459791860.012
response to cytokineGO:00340972320.012
negative regulation of protein maturationGO:19033181420.012
regulation of neuroblast proliferationGO:190269230.012
positive regulation of nf kappab transcription factor activityGO:0051092810.012
regulation of ras protein signal transductionGO:00465781550.012
2 oxoglutarate metabolic processGO:000610340.012
regulation of membrane potentialGO:0042391950.012
cell cell signalingGO:00072671550.012
maintenance of locationGO:00512351120.012
Worm
positive regulation of protein phosphorylationGO:00019343130.012
necrotic cell deathGO:0070265210.012
purine ribonucleoside monophosphate biosynthetic processGO:0009168160.011
regulation of feeding behaviorGO:006025930.011
hematopoietic or lymphoid organ developmentGO:00485341860.011
tube morphogenesisGO:0035239950.011
neurological system processGO:00508771630.011
response to oxygen levelsGO:00704821000.011
regulation of protein localizationGO:00328802960.011
tetrapyrrole biosynthetic processGO:003301470.011
amide transportGO:0042886760.011
negative regulation of cellular protein metabolic processGO:00322693530.011
regulation of protein processingGO:00706131500.011
protein targetingGO:00066051870.011
negative regulation of developmental processGO:00510932470.011
negative regulation of intracellular signal transductionGO:19025321830.011
regulation of protein transportGO:00512232130.011
cell projection organizationGO:00300302520.011
compound eye developmentGO:004874910.011
response to hormoneGO:00097251750.011
Mouse
response to light stimulusGO:0009416870.011
inorganic cation transmembrane transportGO:00986621940.011
protein localization to plasma membraneGO:0072659930.011
rna interferenceGO:001624640.011
membrane fusionGO:0061025430.011
biological adhesionGO:00226103310.011
innate immune responseGO:00450871780.011
positive regulation of kinase activityGO:00336742040.011
multi organism cellular processGO:00447641560.011
microtubule based processGO:00070172100.011
negative regulation of endopeptidase activityGO:0010951840.010
negative regulation of catabolic processGO:00098951040.010
anion transmembrane transportGO:0098656760.010
response to axon injuryGO:004867810.010
tetrapyrrole metabolic processGO:0033013110.010
negative regulation of phosphate metabolic processGO:00459362670.010
single organism carbohydrate metabolic processGO:00447231930.010
interspecies interaction between organismsGO:00444191560.010
regulation of gtp catabolic processGO:00331241800.010
motor neuron axon guidanceGO:000804520.010
midbrain developmentGO:0030901450.010
regulation of peptidyl tyrosine phosphorylationGO:00507301080.010

HADHA disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:00146672950.813
inherited metabolic disorderDOID:6552420.813
amino acid metabolic disorderDOID:9252500.047
sensory system diseaseDOID:00501552030.042
eye and adnexa diseaseDOID:14921500.042
eye diseaseDOID:56141490.042
nervous system diseaseDOID:8634310.042
central nervous system diseaseDOID:3311860.039
kidney diseaseDOID:557360.033
urinary system diseaseDOID:18400.033
hyperinsulinemic hypoglycemiaDOID:1331770.033
carbohydrate metabolic disorderDOID:2978550.033
disease of cellular proliferationDOID:145661740.027
retinal diseaseDOID:56791180.020
cancerDOID:1621670.020
neurodegenerative diseaseDOID:12891020.020
cardiovascular system diseaseDOID:12871060.020
organ system cancerDOID:00506861640.019
endocrine gland cancerDOID:170260.019
musculoskeletal system diseaseDOID:172230.013
retinal degenerationDOID:8466890.013
retinitis pigmentosaDOID:10584510.013