Homo sapiens

9 known processes

SDHB

succinate dehydrogenase complex, subunit B, iron sulfur (Ip)

(Aliases: SDH2,SDH1,IP,PGL4,SDHIP,SDH,FLJ92337)

SDHB biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
purine nucleoside triphosphate metabolic processGO:00091444120.672
Fly
purine ribonucleoside triphosphate metabolic processGO:00092054110.653
Fly
ribonucleoside triphosphate metabolic processGO:00091994120.647
Fly
purine ribonucleoside metabolic processGO:00461284370.540
Fly
nucleoside triphosphate metabolic processGO:00091414220.531
Fly
purine nucleoside monophosphate metabolic processGO:00091261860.527
Fly
cellular respirationGO:0045333210.526
Rat Fly
purine ribonucleoside monophosphate metabolic processGO:00091671860.521
Fly
ribonucleoside monophosphate metabolic processGO:00091611870.458
Fly
post embryonic developmentGO:000979120.450
Worm
oxidation reduction processGO:00551143960.401
Rat Fly
atp metabolic processGO:00460341760.327
Fly
nervous system developmentGO:00073992930.318
generation of precursor metabolites and energyGO:0006091680.254
Rat Fly
atp synthesis coupled electron transportGO:004277340.249
Fly
determination of adult lifespanGO:000834020.206
Worm
adult locomotory behaviorGO:000834410.156
vesicle mediated transportGO:00161923710.147
lipid localizationGO:00108761060.140
oxidative phosphorylationGO:0006119100.130
Fly
energy derivation by oxidation of organic compoundsGO:0015980430.120
Rat Fly
succinate metabolic processGO:000610510.118
Rat
aerobic respirationGO:000906070.109
negative regulation of cell deathGO:00605483450.104
regulation of purine nucleotide metabolic processGO:19005422640.099
cellular amine metabolic processGO:0044106410.093
regulation of nucleoside metabolic processGO:00091182090.093
regulation of cellular amine metabolic processGO:0033238110.087
microtubule cytoskeleton organizationGO:00002261760.083
cellular amino acid metabolic processGO:00065201160.082
embryo developmentGO:00097901230.079
Worm
organophosphate biosynthetic processGO:00904071630.078
negative regulation of apoptotic processGO:00430663160.076
purine nucleoside triphosphate catabolic processGO:00091463920.075
amine metabolic processGO:0009308440.074
regulation of cellular ketone metabolic processGO:0010565500.069
regulation of cellular amino acid metabolic processGO:000652160.068
cellular ketone metabolic processGO:0042180800.067
nucleoside phosphate biosynthetic processGO:19012931090.065
ribonucleotide catabolic processGO:00092614050.064
lipid metabolic processGO:00066293810.062
glycosyl compound catabolic processGO:19016584130.061
locomotory behaviorGO:000762610.061
mitochondrion organizationGO:00070051560.059
carbohydrate derivative biosynthetic processGO:19011372070.058
respiratory electron transport chainGO:002290470.058
Rat Fly
ribose phosphate biosynthetic processGO:0046390820.056
negative regulation of apoptotic signaling pathwayGO:2001234970.055
cation transportGO:00068123310.054
negative regulation of phosphorus metabolic processGO:00105632670.054
organonitrogen compound biosynthetic processGO:19015662000.053
negative regulation of programmed cell deathGO:00430693210.051
purine ribonucleoside triphosphate catabolic processGO:00092073910.050
cellular chemical homeostasisGO:00550821800.050
regulation of nucleotide catabolic processGO:00308112050.050
mitochondrial respiratory chain complex assemblyGO:0033108230.049
nucleoside monophosphate metabolic processGO:00091231910.048
Fly
mitochondrial transportGO:0006839600.047
negative regulation of catalytic activityGO:00430863350.045
chemical homeostasisGO:00488783060.045
regulation of purine nucleotide catabolic processGO:00331212050.044
spinal cord developmentGO:002151040.043
purine ribonucleoside catabolic processGO:00461303980.042
reactive oxygen species metabolic processGO:0072593750.042
growthGO:00400072020.041
nucleoside catabolic processGO:00091644080.041
purine nucleotide biosynthetic processGO:0006164840.040
regulation of membrane potentialGO:0042391950.040
metal ion homeostasisGO:00550651690.039
cation transmembrane transportGO:00986552380.039
maintenance of locationGO:00512351120.038
ribonucleoside triphosphate catabolic processGO:00092033910.038
circulatory system developmentGO:00723592620.037
regulation of mitochondrial membrane potentialGO:0051881230.037
negative regulation of phosphate metabolic processGO:00459362670.037
nucleoside triphosphate catabolic processGO:00091433940.036
cellular calcium ion homeostasisGO:00068741170.036
ribonucleoside catabolic processGO:00424544060.035
positive regulation of nucleoside metabolic processGO:00459791860.035
ras protein signal transductionGO:0007265730.035
epithelial tube branching involved in lung morphogenesisGO:006044140.034
proximal tubule developmentGO:007201410.034
cellular cation homeostasisGO:00300031630.034
female gamete generationGO:000729220.034
regulation of nucleotide metabolic processGO:00061402690.034
organophosphate catabolic processGO:00464344300.034
response to oxidative stressGO:00069791210.033
small molecule biosynthetic processGO:00442831570.033
lipid biosynthetic processGO:00086101770.033
neuromuscular junction developmentGO:000752830.032
ion homeostasisGO:00508012300.032
inorganic cation transmembrane transportGO:00986621940.031
cofactor metabolic processGO:0051186870.031
steroid metabolic processGO:0008202940.031
protein oligomerizationGO:00512591730.031
multicellular organismal agingGO:001025930.030
Worm
mitochondrial atp synthesis coupled electron transportGO:004277540.030
Fly
purine ribonucleoside biosynthetic processGO:0046129230.029
response to hormoneGO:00097251750.029
cellular homeostasisGO:00197251960.029
nucleotide catabolic processGO:00091664080.029
purine nucleotide catabolic processGO:00061954050.029
regulation of neurotrophin trk receptor signaling pathwayGO:005138620.028
cellular metal ion homeostasisGO:00068751460.028
apoptotic mitochondrial changesGO:0008637570.028
hydrogen transportGO:0006818230.028
monovalent inorganic cation transportGO:00156721280.028
negative regulation of protein metabolic processGO:00512483910.027
negative regulation of cellular amine metabolic processGO:003323930.027
cation homeostasisGO:00550801890.027
negative regulation of cell proliferationGO:00082852280.027
regulation of apoptotic signaling pathwayGO:20012331750.027
regenerationGO:003109940.026
membrane organizationGO:00610242920.026
negative regulation of neurotrophin trk receptor signaling pathwayGO:005138720.026
ion transmembrane transportGO:00342203380.025
apoptotic signaling pathwayGO:00971902680.025
positive regulation of cell proliferationGO:00082843010.025
single organism cellular localizationGO:19025803320.025
positive regulation of hydrolase activityGO:00513453310.025
regulation of kinase activityGO:00435493140.025
positive regulation of cell deathGO:00109422630.025
cellular ion homeostasisGO:00068731680.025
tube developmentGO:00352951250.024
negative regulation of hydrolase activityGO:00513461820.024
positive regulation of protein kinase activityGO:00458601900.024
cofactor transportGO:0051181110.024
embryo development ending in birth or egg hatchingGO:0009792340.024
Worm
lipid oxidationGO:0034440330.024
purine nucleoside catabolic processGO:00061523980.023
negative regulation of intracellular signal transductionGO:19025321830.023
mitotic cell cycle processGO:19030472860.023
negative regulation of cellular amino acid metabolic processGO:004576320.023
gtp catabolic processGO:00061842370.023
purine containing compound biosynthetic processGO:0072522880.023
negative regulation of cellular protein metabolic processGO:00322693530.023
purine ribonucleotide catabolic processGO:00091544040.023
negative regulation of cellular component organizationGO:00511292350.023
positive regulation of phosphorylationGO:00423273940.022
regulation of oxidoreductase activityGO:0051341430.022
purine ribonucleoside monophosphate biosynthetic processGO:0009168160.022
mitotic cell cycleGO:00002783260.022
small gtpase mediated signal transductionGO:0007264780.022
positive regulation of cellular amino acid metabolic processGO:004576430.022
positive regulation of nucleotide metabolic processGO:00459812300.022
lipid storageGO:0019915280.021
ribonucleoside monophosphate catabolic processGO:00091581580.021
microtubule based processGO:00070172100.021
purine nucleoside biosynthetic processGO:0042451230.021
endocytosisGO:00068971590.021
dicarboxylic acid metabolic processGO:0043648290.021
Rat
purine containing compound catabolic processGO:00725234110.021
negative regulation of catabolic processGO:00098951040.021
spermatid differentiationGO:004851540.020
regulation of transferase activityGO:00513383550.020
cell growthGO:00160491600.020
response to antibioticGO:0046677150.020
cell cell signalingGO:00072671550.020
lung growthGO:006043720.020
negative regulation of transportGO:00510511760.019
anatomical structure formation involved in morphogenesisGO:00486462840.019
anatomical structure homeostasisGO:00602491000.019
receptor mediated endocytosisGO:0006898840.019
electron transport chainGO:002290080.019
Rat Fly
purine ribonucleotide biosynthetic processGO:0009152790.019
regulation of neural precursor cell proliferationGO:200017740.019
protein maturationGO:00516042330.019
alcohol biosynthetic processGO:0046165520.019
organic hydroxy compound metabolic processGO:19016151470.019
cellular component morphogenesisGO:00329893140.019
regulation of gtp catabolic processGO:00331241800.018
inner ear morphogenesisGO:004247240.018
cell differentiation in spinal cordGO:002151510.018
guanosine containing compound catabolic processGO:19010692390.018
positive regulation of transferase activityGO:00513472270.018
cellular macromolecular complex assemblyGO:00346223240.018
mitochondrial calcium ion homeostasisGO:0051560110.018
sensory perceptionGO:00076001030.018
nucleoside phosphate catabolic processGO:19012924120.018
positive regulation of cellular amine metabolic processGO:003324070.018
mitochondrial membrane organizationGO:0007006400.018
cellular response to oxidative stressGO:0034599850.018
cellular protein catabolic processGO:00442572610.018
segmentationGO:003528240.018
negative regulation of nucleotide metabolic processGO:0045980290.017
transmembrane transportGO:00550853990.017
proteolysis involved in cellular protein catabolic processGO:00516032440.017
regulation of atp metabolic processGO:1903578290.017
alcohol metabolic processGO:00060661140.017
negative regulation of organelle organizationGO:00106391260.017
striated muscle tissue developmentGO:0014706590.017
reproductive structure developmentGO:0048608550.017
mitochondrial electron transport nadh to ubiquinoneGO:000612020.017
nucleotide biosynthetic processGO:00091651090.016
positive regulation of programmed cell deathGO:00430682490.016
cofactor biosynthetic processGO:0051188310.016
purine nucleoside monophosphate biosynthetic processGO:0009127160.016
negative regulation of cellular catabolic processGO:0031330830.016
lipid catabolic processGO:0016042840.016
nucleoside monophosphate catabolic processGO:00091251590.016
agingGO:0007568660.016
Worm
regulation of ras protein signal transductionGO:00465781550.016
guanosine containing compound metabolic processGO:19010682440.016
regulation of gtpase activityGO:00430871800.016
immune system developmentGO:00025201950.016
steroid biosynthetic processGO:0006694460.016
matingGO:000761810.016
gtp metabolic processGO:00460392390.016
head developmentGO:00603221080.016
organelle localizationGO:0051640840.015
peptidyl serine modificationGO:00182091060.015
reproductionGO:0000003630.015
Worm
cellular divalent inorganic cation homeostasisGO:00725031280.015
biological adhesionGO:00226103310.015
carboxylic acid transportGO:0046942630.015
positive regulation of kinase activityGO:00336742040.015
peptidyl serine phosphorylationGO:00181051010.015
positive regulation of protein phosphorylationGO:00019343130.015
neurological system processGO:00508771630.015
epithelium developmentGO:00604292270.015
nitrogen compound transportGO:00717051910.015
positive regulation of mapk cascadeGO:00434101900.015
ribonucleoside biosynthetic processGO:0042455250.015
protein localization to organelleGO:00333652800.015
system processGO:00030083490.015
establishment of organelle localizationGO:0051656590.015
negative regulation of mitochondrion organizationGO:0010823220.015
ribonucleotide biosynthetic processGO:0009260810.014
oogenesisGO:004847720.014
developmental growthGO:0048589480.014
regulation of small gtpase mediated signal transductionGO:00510561560.014
organic anion transportGO:00157111030.014
nadh dehydrogenase complex assemblyGO:0010257160.014
metal ion transportGO:00300012720.014
regulation of proteolysisGO:00301622930.014
mitochondrial respiratory chain complex i biogenesisGO:0097031160.013
organic hydroxy compound biosynthetic processGO:1901617710.013
cellular macromolecule catabolic processGO:00442653800.013
regulation of peptidyl serine phosphorylationGO:0033135500.013
cellular response to endogenous stimulusGO:00714953360.013
innate immune responseGO:00450871780.013
secretion by cellGO:00329402260.013
tissue regenerationGO:004224630.013
reproductive system developmentGO:0061458560.013
myosin filament organizationGO:003103320.013
ventral spinal cord developmentGO:002151710.013
positive regulation of cell cycleGO:00457871400.013
regulation of lipid metabolic processGO:0019216960.013
divalent inorganic cation homeostasisGO:00725071360.013
immune responseGO:00069553070.013
response to reactive oxygen speciesGO:0000302610.013
inorganic ion transmembrane transportGO:00986602310.013
cytoplasmic transportGO:00164823790.012
rho protein signal transductionGO:0007266260.012
protein kinase b signalingGO:0043491690.012
calcium ion homeostasisGO:00550741220.012
hydrogen ion transmembrane transportGO:1902600150.012
positive regulation of purine nucleotide metabolic processGO:19005442270.012
negative regulation of phosphorylationGO:00423261740.012
mapk cascadeGO:00001652880.012
blood vessel morphogenesisGO:00485141620.012
actin filament based processGO:00300292240.012
positive regulation of peptidyl serine phosphorylationGO:0033138420.012
hindbrain developmentGO:003090230.012
negative regulation of kinase activityGO:00336731060.012
cell adhesionGO:00071553250.012
calcium ion transportGO:00068161470.012
regulation of neuroblast proliferationGO:190269230.012
regulation of intracellular transportGO:00323861950.012
negative regulation of multicellular organismal processGO:00512413170.011
anion transportGO:00068201610.011
atp catabolic processGO:00062001570.011
positive regulation of mitochondrial membrane permeabilityGO:0035794170.011
negative regulation of nucleotide catabolic processGO:0030812160.011
behaviorGO:00076101120.011
positive regulation of immune system processGO:00026842830.011
neurogenesisGO:00220081690.011
negative regulation of growthGO:0045926970.011
negative regulation of neural precursor cell proliferationGO:200017810.011
tetrapyrrole biosynthetic processGO:003301470.011
central nervous system developmentGO:00074171230.011
positive regulation of cellular component organizationGO:00511303760.011
positive regulation of developmental processGO:00510943140.011
branch elongation of an epitheliumGO:006060230.011
protein catabolic processGO:00301633250.011
osteoblast differentiationGO:0001649920.011
cytokine productionGO:00018162470.011
atp biosynthetic processGO:0006754110.011
nucleoside triphosphate biosynthetic processGO:0009142200.011
atp transportGO:001586740.011
embryonic organ developmentGO:0048568360.011
negative regulation of purine nucleotide metabolic processGO:1900543280.011
axis elongationGO:000340140.011
fatty acid metabolic processGO:00066311150.011
modification dependent protein catabolic processGO:00199412090.011
cell part morphogenesisGO:00329901370.011
regulation of cellular response to stressGO:00801352440.010
regulation of atpase activityGO:0043462250.010
protein processingGO:00164852260.010
regulation of growthGO:00400081650.010
dna replicationGO:00062601160.010
action potentialGO:0001508340.010
cellular response to growth factor stimulusGO:00713631970.010
organic acid transportGO:0015849650.010
myosin filament assemblyGO:003103420.010
negative regulation of nucleoside metabolic processGO:0045978180.010
blastoderm segmentationGO:000735020.010
protein homooligomerizationGO:00512601000.010
positive regulation of apoptotic processGO:00430652460.010
regulation of synaptic plasticityGO:004816730.010
regulation of cell differentiationGO:00455953930.010
regulation of protein kinase activityGO:00458592890.010

SDHB disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
inherited metabolic disorderDOID:6552420.905
leigh diseaseDOID:3652160.905
mitochondrial metabolism diseaseDOID:700290.905
disease of metabolismDOID:00146672950.905
cardiovascular system diseaseDOID:12871060.465
cardiomyopathyDOID:0050700500.465
musculoskeletal system diseaseDOID:172230.465
muscle tissue diseaseDOID:661130.465
myopathyDOID:4231040.465
muscular diseaseDOID:00800001140.465
heart diseaseDOID:114680.465
intrinsic cardiomyopathyDOID:0060036500.261
disease of cellular proliferationDOID:145661740.100
organ system cancerDOID:00506861640.097
cancerDOID:1621670.097
endocrine gland cancerDOID:170260.097
central nervous system diseaseDOID:3311860.021
nervous system diseaseDOID:8634310.021
eye diseaseDOID:56141490.021
eye and adnexa diseaseDOID:14921500.021
sensory system diseaseDOID:00501552030.021
retinal diseaseDOID:56791180.012
retinal degenerationDOID:8466890.012
immune system diseaseDOID:29141550.011
neurodegenerative diseaseDOID:12891020.010
gastrointestinal system cancerDOID:3119520.003
cell type benign neoplasmDOID:0060084100.002
phaeochromocytomaDOID:005077180.002
benign neoplasmDOID:0060072180.002
gastrointestinal stromal tumorDOID:925340.001