Homo sapiens

195 known processes

IGF1R

insulin-like growth factor 1 receptor

(Aliases: IGFR,MGC142172,MGC142170,IGFIR,CD221,MGC18216,JTK13)

IGF1R biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of glycogen metabolic processGO:0070873150.999
Human
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.998
small gtpase mediated signal transductionGO:0007264780.998
activation of mapk activityGO:0000187450.996
positive regulation of map kinase activityGO:0043406800.995
positive regulation of mesenchymal cell proliferationGO:000205320.994
cellular response to phGO:007146790.993
Human
insulin like growth factor receptor signaling pathwayGO:0048009130.988
positive regulation of transferase activityGO:00513472270.986
ras protein signal transductionGO:0007265730.985
regulation of cell motilityGO:20001452990.983
positive regulation of catabolic processGO:00098963100.981
Human
glycogen biosynthetic processGO:0005978160.974
Human
regulation of cardiac muscle cell apoptotic processGO:001066530.974
Human
positive regulation of phosphorylationGO:00423273940.973
transformation of host cell by virusGO:001908720.973
Human
regulation of locomotionGO:00400123290.972
positive regulation of glycogen biosynthetic processGO:0045725100.969
Human
regulation of activin receptor signaling pathwayGO:0032925140.969
cellular response to endogenous stimulusGO:00714953360.969
Human Fly
rho protein signal transductionGO:0007266260.968
positive regulation of glucose import in response to insulin stimulusGO:200127530.968
regulation of cell migrationGO:00303342890.968
positive regulation of protein phosphorylationGO:00019343130.964
regulation of rho protein signal transductionGO:0035023790.952
positive regulation of glycogen metabolic processGO:0070875100.952
Human
positive regulation of cellular catabolic processGO:00313312840.951
Human
regulation of glucan biosynthetic processGO:0010962140.948
Human
enzyme linked receptor protein signaling pathwayGO:00071673030.946
positive regulation of mapk cascadeGO:00434101900.946
regulation of kinase activityGO:00435493140.945
positive regulation of glycolytic processGO:004582140.944
Human
inositol lipid mediated signalingGO:0048017550.942
cell developmentGO:00484683280.939
Human Rat Fly
cellular polysaccharide biosynthetic processGO:0033692210.938
Human
regulation of protein serine threonine kinase activityGO:00719001790.934
erk1 and erk2 cascadeGO:00703711040.931
lipid metabolic processGO:00066293810.925
Rat Fly
positive regulation of rho gtpase activityGO:0032321560.921
positive regulation of cell migrationGO:00303351720.920
regulation of protein kinase activityGO:00458592890.917
positive regulation of respiratory burstGO:006026750.912
Human
neuron differentiationGO:00301821380.912
Human Zebrafish Rat Fly
cellular response to dna damage stimulusGO:00069743790.906
Fly
cellular response to nitrogen compoundGO:19016991440.899
Human Fly
positive regulation of rho protein signal transductionGO:003502540.892
stem cell divisionGO:001714520.892
Fly
positive regulation of protein kinase activityGO:00458601900.891
ion transmembrane transportGO:00342203380.890
glucan biosynthetic processGO:0009250160.888
Human
asymmetric stem cell divisionGO:009872210.886
Fly
behaviorGO:00076101120.881
Fly
carbohydrate transportGO:0008643370.880
Human
regulation of neuron differentiationGO:0045664700.879
Human
associative learningGO:000830610.879
phosphatidylinositol 3 kinase signalingGO:0014065480.877
Human
positive regulation of gtpase activityGO:00435471660.877
negative regulation of secretionGO:0051048580.873
cellular component morphogenesisGO:00329893140.873
Rat Fly
negative regulation of programmed cell deathGO:00430693210.872
energy reserve metabolic processGO:0006112220.870
Human
inactivation of mapkk activityGO:005138910.868
positive regulation of cell proliferationGO:00082843010.863
Human Fly
axon regenerationGO:003110310.860
reactive oxygen species biosynthetic processGO:190340940.851
mapk cascadeGO:00001652880.851
response to phGO:0009268120.851
Human
g protein coupled receptor signaling pathwayGO:00071862070.849
Human
epithelium developmentGO:00604292270.848
Mouse
morphogenesis of embryonic epitheliumGO:001633140.847
multicellular organismal agingGO:001025930.845
Worm Fly
regulation of striated muscle cell apoptotic processGO:001066230.843
Human
phosphatidylinositol mediated signalingGO:0048015550.842
response to oxygen containing compoundGO:19017003690.841
Human Rat Worm Fly
chemotaxisGO:00069351570.840
Fly
regulation of embryonic developmentGO:0045995200.839
Human
intracellular protein transportGO:00068862700.839
Worm
regulation of cell cycle processGO:00105642660.838
Human Mouse Rat
regulation of transferase activityGO:00513383550.838
transmembrane transportGO:00550853990.832
positive regulation of secretion by cellGO:19035321080.812
neuron projection regenerationGO:003110210.811
actin filament based movementGO:0030048170.810
regulation of small gtpase mediated signal transductionGO:00510561560.810
positive regulation of locomotionGO:00400171860.809
actin filament based processGO:00300292240.809
Human
monosaccharide metabolic processGO:0005996740.806
Human
positive regulation of protein kinase b signalingGO:0051897420.802
Human Mouse
positive regulation of glucose metabolic processGO:0010907120.798
Human
positive regulation of developmental processGO:00510943140.794
Human Worm Fly
regulation of intracellular protein transportGO:00331571230.793
Worm
activation of protein kinase activityGO:0032147900.793
regulation of glycogen biosynthetic processGO:0005979140.793
Human
negative regulation of cellular carbohydrate metabolic processGO:0010677140.792
purine ribonucleoside metabolic processGO:00461284370.782
purine ribonucleoside triphosphate catabolic processGO:00092073910.774
protein heterotetramerizationGO:005129030.773
Human
circadian sleep wake cycle processGO:002241020.765
Fly
mammary gland developmentGO:0030879170.765
Mouse
positive regulation of tyrosine phosphorylation of stat5 proteinGO:0042523110.764
circadian behaviorGO:004851220.759
Fly
cell morphogenesis involved in differentiationGO:00009041440.759
Rat Fly
regulation of ras protein signal transductionGO:00465781550.757
cellular amine metabolic processGO:0044106410.755
glucan metabolic processGO:0044042220.752
Human
regulation of cellular component movementGO:00512703340.752
cell cell signalingGO:00072671550.751
post embryonic developmentGO:000979120.751
Worm
regulation of mapk cascadeGO:00434082620.750
regenerationGO:003109940.745
Zebrafish
negative regulation of wnt signaling pathwayGO:0030178690.739
regulation of cellular amino acid metabolic processGO:000652160.737
positive regulation of ras gtpase activityGO:00323201170.736
positive regulation of tyrosine phosphorylation of stat proteinGO:0042531280.735
response to axon injuryGO:004867810.733
muscle cell migrationGO:0014812190.715
positive regulation of glycoprotein biosynthetic processGO:001056060.714
carbohydrate metabolic processGO:00059752070.711
Human Fly
protein heterooligomerizationGO:0051291160.709
Human Rat
regulation of cell morphogenesis involved in differentiationGO:0010769830.707
polysaccharide biosynthetic processGO:0000271270.698
Human
mitotic cell cycleGO:00002783260.697
Human Mouse
purine containing compound catabolic processGO:00725234110.691
ribonucleoside triphosphate catabolic processGO:00092033910.691
photoreceptor cell differentiationGO:004653020.690
monocarboxylic acid metabolic processGO:00327871850.689
Human
positive regulation of cellular component movementGO:00512721810.687
regulation of cell cycleGO:00517263930.687
Human Mouse Rat
positive regulation of cellular amino acid metabolic processGO:004576430.685
head developmentGO:00603221080.684
Mouse
glucose homeostasisGO:0042593310.682
Human
cellular response to oxygen containing compoundGO:19017012760.681
Human Fly
positive regulation of peptide hormone secretionGO:0090277150.668
negative regulation of cell deathGO:00605483450.668
positive regulation of fatty acid beta oxidationGO:003200050.664
regulation of sequence specific dna binding transcription factor activityGO:00510902110.661
Mouse
regulation of glucose metabolic processGO:0010906280.659
Human
regulation of nucleoside metabolic processGO:00091182090.658
regulation of protein transportGO:00512232130.656
Worm
determination of adult lifespanGO:000834020.654
Worm Fly
regulation of ras gtpase activityGO:00323181280.654
cell activationGO:00017752130.652
positive regulation of cellular response to insulin stimulusGO:190007860.650
cellular polysaccharide metabolic processGO:0044264270.648
Human
regulation of generation of precursor metabolites and energyGO:0043467270.644
Human
monosaccharide transportGO:0015749320.642
Human
regulation of anatomical structure morphogenesisGO:00226032860.637
gtp metabolic processGO:00460392390.636
regulation of lipid catabolic processGO:0050994230.634
protein targetingGO:00066051870.630
Worm
regulation of nucleotide catabolic processGO:00308112050.628
neurogenesisGO:00220081690.627
Human Zebrafish Rat Fly
response to other organismGO:00517072610.627
regulation of cellular carbohydrate metabolic processGO:0010675470.626
Human
generation of neuronsGO:00486991520.623
Human Zebrafish Rat Fly
response to alkaline phGO:001044620.618
Human
actin mediated cell contractionGO:0070252120.615
oxidation reduction processGO:00551143960.611
Human
male genitalia developmentGO:003053910.608
negative regulation of ion transmembrane transportGO:0034766260.599
regulation of secretionGO:00510461940.594
regulation of erk1 and erk2 cascadeGO:0070372990.588
positive regulation of small gtpase mediated signal transductionGO:0051057120.587
peptidyl tyrosine modificationGO:00182121700.583
positive regulation of cell motilityGO:20001471770.582
protein oligomerizationGO:00512591730.582
negative regulation of apoptotic processGO:00430663160.578
cellular amino acid metabolic processGO:00065201160.577
cellular response to hormone stimulusGO:00328701250.577
Human Fly
regulation of phosphatidylinositol 3 kinase signalingGO:0014066350.574
positive regulation of sequence specific dna binding transcription factor activityGO:00510911310.573
organelle fissionGO:00482851490.572
Human Mouse
regulation of polysaccharide metabolic processGO:0032881210.572
Human
biological adhesionGO:00226103310.566
regulation of cell differentiationGO:00455953930.563
Human
response to organonitrogen compoundGO:00102431560.561
Human Fly
regulation of cell morphogenesisGO:00226041530.558
regulation of behaviorGO:0050795820.558
Fly
regulation of nucleocytoplasmic transportGO:0046822980.557
Worm
interspecies interaction between organismsGO:00444191560.555
Human
positive regulation of reactive oxygen species biosynthetic processGO:190342820.553
peptide secretionGO:0002790510.552
glycosyl compound catabolic processGO:19016584130.552
cell morphogenesisGO:00009022960.550
Rat Fly
cellular response to peptide hormone stimulusGO:0071375560.549
Human Fly
neuroblast proliferationGO:000740540.543
regulation of reactive oxygen species biosynthetic processGO:190342630.542
positive regulation of mitotic cell cycleGO:0045931600.529
Human Mouse
axon developmentGO:0061564340.525
Rat Fly
digestive system developmentGO:0055123750.521
Mouse
positive regulation of dna replicationGO:0045740350.520
regulation of immune responseGO:00507762010.519
purine ribonucleoside triphosphate metabolic processGO:00092054110.518
regulation of establishment of protein localizationGO:00702012420.518
Worm
regulation of neurogenesisGO:0050767820.517
Human
peripheral nervous system developmentGO:000742220.515
cellular glucan metabolic processGO:0006073220.509
Human
glucose transportGO:0015758300.509
Human
cellular response to peptideGO:1901653590.506
Human Fly
positive regulation of phosphatidylinositol 3 kinase signalingGO:0014068280.506
muscle cell differentiationGO:0042692630.502
Fly
positive regulation of protein serine threonine kinase activityGO:00719021190.501
regulation of rho gtpase activityGO:0032319660.500
cellular carbohydrate biosynthetic processGO:0034637210.500
Human
protein autophosphorylationGO:00467771230.491
positive regulation of nucleotide catabolic processGO:00308131850.489
positive regulation of erk1 and erk2 cascadeGO:0070374750.480
positive regulation of nucleoside metabolic processGO:00459791860.478
regulation of tyrosine phosphorylation of stat5 proteinGO:0042522120.478
monocarboxylic acid catabolic processGO:0072329370.477
response to peptideGO:1901652650.476
Human Fly
peptide transportGO:0015833740.472
neuron developmentGO:00486661130.465
Human Rat Fly
positive regulation of muscle cell apoptotic processGO:001066140.463
Human
regulation of glucose transportGO:0010827230.462
Human
glucose import in response to insulin stimulusGO:004438140.462
regulation of gtpase activityGO:00430871800.462
regulation of tyrosine phosphorylation of stat proteinGO:0042509300.458
signal releaseGO:0023061700.456
protein targeting to nucleusGO:00447441040.453
Worm
regulation of peptide hormone secretionGO:0090276410.453
guanosine containing compound metabolic processGO:19010682440.450
protein kinase b signalingGO:0043491690.450
Human Mouse
regulation of peptide secretionGO:0002791420.436
negative regulation of circadian sleep wake cycle sleepGO:004232110.433
Fly
positive regulation of kinase activityGO:00336742040.431
rhythmic behaviorGO:000762220.428
Fly
regulation of glucose importGO:0046324210.424
Human
taxisGO:00423301570.420
Fly
regulation of fatty acid beta oxidationGO:003199880.420
cellular lipid metabolic processGO:00442553030.419
jnk cascadeGO:0007254800.413
ameboidal type cell migrationGO:00016671350.413
cellular response to organonitrogen compoundGO:00714171240.412
Human Fly
reactive nitrogen species metabolic processGO:200105730.412
positive regulation of peptidyl tyrosine phosphorylationGO:0050731850.410
gastrulationGO:0007369510.407
ribonucleotide catabolic processGO:00092614050.406
carbohydrate biosynthetic processGO:0016051420.405
Human
positive regulation of tyrosine phosphorylation of stat3 proteinGO:0042517160.402
guanosine containing compound catabolic processGO:19010692390.398
immune responseGO:00069553070.394
response to biotic stimulusGO:00096072760.394
ribonucleoside triphosphate metabolic processGO:00091994120.389
regulation of immune effector processGO:0002697910.388
single organism behaviorGO:0044708280.387
Fly
cardiovascular system developmentGO:00723582620.384
Human Zebrafish
positive regulation of nucleotide metabolic processGO:00459812300.380
negative regulation of fatty acid transportGO:200019260.377
mammary gland involutionGO:006005610.376
response to manganese ionGO:001004220.367
positive regulation of fatty acid metabolic processGO:0045923110.364
regulation of hormone secretionGO:0046883570.364
positive regulation of cell cycleGO:00457871400.362
Human Mouse Rat
cell projection morphogenesisGO:00488581290.360
Rat Fly
neuron projection morphogenesisGO:0048812500.358
Rat Fly
generation of precursor metabolites and energyGO:0006091680.357
Human
glycogen metabolic processGO:0005977220.356
Human
cognitionGO:0050890430.356
regulation of intracellular transportGO:00323861950.346
Worm
positive regulation of cellular amine metabolic processGO:003324070.338
organophosphate catabolic processGO:00464344300.335
positive regulation of hormone secretionGO:0046887250.333
regulation of secretion by cellGO:19035301770.332
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.330
glucose importGO:0046323240.329
Human
regulation of cellular ketone metabolic processGO:0010565500.328
tube morphogenesisGO:0035239950.325
Zebrafish
response to mechanical stimulusGO:0009612510.325
nucleoside triphosphate metabolic processGO:00091414220.323
digestive tract morphogenesisGO:0048546560.321
regulation of reactive oxygen species metabolic processGO:2000377410.321
Fly
mitotic sister chromatid segregationGO:0000070530.319
regulation of purine nucleotide metabolic processGO:19005422640.319
negative regulation of secretion by cellGO:1903531520.319
regulation of protein localization to nucleusGO:1900180850.318
Worm
positive regulation of reactive oxygen species metabolic processGO:2000379240.318
hexose metabolic processGO:0019318550.316
Human
modification dependent macromolecule catabolic processGO:00436322120.307
cellular lipid catabolic processGO:0044242650.305
fatty acid catabolic processGO:0009062290.305
vascular endothelial growth factor receptor signaling pathwayGO:0048010190.303
positive regulation of dna metabolic processGO:0051054730.303
anatomical structure homeostasisGO:00602491000.301
Fly
multi organism cellular processGO:00447641560.301
Human
nervous system developmentGO:00073992930.297
Human Zebrafish Mouse Rat Fly
negative regulation of protein transportGO:0051224750.295
Worm
negative regulation of cytoplasmic transportGO:1903650460.292
Worm
peptide hormone secretionGO:0030072500.290
positive regulation of vasoconstrictionGO:004590730.290
energy derivation by oxidation of organic compoundsGO:0015980430.289
Human
apoptotic signaling pathwayGO:00971902680.288
activation of protein kinase b activityGO:0032148140.288
Human
positive regulation of cell deathGO:00109422630.288
Human
regulation of tyrosine phosphorylation of stat3 proteinGO:0042516180.286
positive regulation of insulin receptor signaling pathwayGO:004662830.284
signal transduction by phosphorylationGO:00230142970.284
regulation of purine nucleotide catabolic processGO:00331212050.281
purine nucleoside triphosphate catabolic processGO:00091463920.280
regulation of proteolysisGO:00301622930.276
Zebrafish
sex determinationGO:000753030.273
Mouse
gland developmentGO:0048732480.273
Mouse
neuron apoptotic processGO:0051402390.272
regulation of peptidyl tyrosine phosphorylationGO:00507301080.270
regulation of fatty acid transportGO:200019180.267
blastoderm segmentationGO:000735020.267
negative regulation of intracellular transportGO:0032387600.267
Worm
nucleoside phosphate catabolic processGO:19012924120.265
regulation of cytokine productionGO:00018172320.262
regulation of nuclear divisionGO:0051783650.262
Human Mouse
positive regulation of peptidyl serine phosphorylationGO:0033138420.261
hydrogen peroxide metabolic processGO:0042743200.261
cytoplasmic transportGO:00164823790.260
Worm
purine nucleotide catabolic processGO:00061954050.260
cell divisionGO:00513011680.259
Human Mouse Rat Fly
regulation of nucleotide metabolic processGO:00061402690.256
hormone secretionGO:0046879650.255
negative regulation of feeding behaviorGO:200025210.255
Fly
nucleoside catabolic processGO:00091644080.254
central nervous system developmentGO:00074171230.254
Zebrafish Mouse
regulation of glucose import in response to insulin stimulusGO:200127340.251
regulation of protein localizationGO:00328802960.250
Worm
negative regulation of protein phosphorylationGO:00019331400.250
reproductive processGO:00224141060.246
Zebrafish Mouse Worm Fly
taurine metabolic processGO:001953010.246
embryonic viscerocranium morphogenesisGO:004870310.244
brain developmentGO:0007420970.242
Mouse
single organism cellular localizationGO:19025803320.242
Worm
secretion by cellGO:00329402260.242
purine nucleoside catabolic processGO:00061523980.241
gtp catabolic processGO:00061842370.240
regulation of nervous system developmentGO:0051960880.239
Human
positive regulation of transportGO:00510503360.238
Human
regulation of transmembrane transportGO:00347621390.238
small molecule catabolic processGO:0044282920.237
nitrogen compound transportGO:00717051910.236
negative regulation of erk1 and erk2 cascadeGO:0070373140.236
steroid metabolic processGO:0008202940.234
Rat
lipid localizationGO:00108761060.234
Worm
positive regulation of hydrolase activityGO:00513453310.233
response to hormoneGO:00097251750.232
Human Fly
cellular protein catabolic processGO:00442572610.230
protein processingGO:00164852260.230
Zebrafish
developmental growthGO:0048589480.230
Human Zebrafish Worm Fly
peptidyl tyrosine phosphorylationGO:00181081700.229
neuron remodelingGO:001632220.227
Fly
embryonic morphogenesisGO:0048598850.226
Zebrafish Fly
neuron deathGO:0070997650.225
regulation of cellular response to stressGO:00801352440.224
female gamete generationGO:000729220.223
Fly
positive regulation of smooth muscle cell proliferationGO:0048661140.222
positive regulation of secretionGO:00510471160.218
neurological system processGO:00508771630.218
response to growth factorGO:00708482050.217
tissue morphogenesisGO:0048729960.216
Mouse
regulation of transcription factor import into nucleusGO:0042990390.216
Worm
morphogenesis of an epitheliumGO:0002009600.215
Mouse
nucleotide catabolic processGO:00091664080.215
system processGO:00030083490.215
regulation of feeding behaviorGO:006025930.215
Fly
regulation of mitosisGO:0007088630.215
Human Mouse
symbiosis encompassing mutualism through parasitismGO:00444031560.215
Human
activation of mapkk activityGO:0000186180.214
protein localization to nucleusGO:00345041360.214
Worm
anatomical structure formation involved in morphogenesisGO:00486462840.214
Fly
regulation of carbohydrate biosynthetic processGO:0043255270.214
Human
regulation of mitotic cell cycle phase transitionGO:19019901180.213
metaphase anaphase transition of cell cycleGO:0044784210.212
extrinsic apoptotic signaling pathwayGO:00971911190.211
peptidyl serine phosphorylationGO:00181051010.210
mitotic nuclear divisionGO:00070671190.210
Human Mouse
cell part morphogenesisGO:00329901370.209
Rat Fly
regulation of multicellular organism growthGO:004001480.208
Worm Fly
negative regulation of leukocyte apoptotic processGO:2000107160.204
response to organic cyclic compoundGO:00140702040.202
Rat Fly
cation homeostasisGO:00550801890.202
establishment of protein localization to plasma membraneGO:0090002680.202
proteasomal protein catabolic processGO:00104981760.199
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.198
regulation of cytoplasmic transportGO:19036491490.195
Worm
regulation of respiratory burstGO:006026380.193
Human
response to nitrogen compoundGO:19016981840.189
Human Fly
hormone transportGO:0009914680.188
single organism membrane organizationGO:00448022680.188
oogenesisGO:004847720.188
Fly
segmentationGO:003528240.185
nerve developmentGO:002167540.183
cellular ketone metabolic processGO:0042180800.183
regulation of neural precursor cell proliferationGO:200017740.183
regulation of ion transmembrane transportGO:00347651320.182
response to abiotic stimulusGO:00096283360.182
Human Worm Fly
single organism carbohydrate catabolic processGO:0044724330.180
Human
pyruvate metabolic processGO:0006090260.180
Human
embryo developmentGO:00097901230.177
Human Zebrafish Fly
response to insulinGO:0032868450.177
Human Fly
regulation of gtp catabolic processGO:00331241800.175
positive regulation of glucose transportGO:0010828170.173
Human
positive regulation of purine nucleotide catabolic processGO:00331231850.173
positive regulation of developmental growthGO:0048639160.173
Human Worm Fly
regulation of cellular amine metabolic processGO:0033238110.172
glycerolipid metabolic processGO:00464861070.171
digestive tract developmentGO:0048565750.170
cellular response to insulin stimulusGO:0032869410.170
Human Fly
stem cell proliferationGO:0072089250.168
positive regulation of apoptotic processGO:00430652460.168
Human
regulation of insulin secretionGO:0050796330.166
regulation of nitric oxide biosynthetic processGO:0045428170.166
Human
apoptotic mitochondrial changesGO:0008637570.165
cytokine productionGO:00018162470.164
viral processGO:00160321460.164
Human
positive regulation of vascular endothelial growth factor receptor signaling pathwayGO:003094960.164
amine metabolic processGO:0009308440.164
actin filament organizationGO:00070151280.162
positive regulation of jak stat cascadeGO:0046427350.159
smooth muscle cell migrationGO:0014909180.156
protein importGO:00170381300.156
Worm
response to cytokineGO:00340972320.155
positive regulation of gtp catabolic processGO:00331261660.155
positive regulation of cell cycle processGO:00900681060.154
Human Mouse Rat
axon guidanceGO:0007411120.154
Fly
negative regulation of cell proliferationGO:00082852280.154
cranial nerve developmentGO:002154540.153
pancreas developmentGO:0031016190.152
Mouse
cellular carbohydrate metabolic processGO:0044262840.152
Human
cellular divalent inorganic cation homeostasisGO:00725031280.152
calcium mediated signaling using intracellular calcium sourceGO:003558470.150
positive regulation of purine nucleotide metabolic processGO:19005442270.145
hexose transportGO:0008645300.144
Human
protein localization to organelleGO:00333652800.142
Worm
skeletal system developmentGO:0001501790.140
muscle system processGO:0003012810.139
lipid modificationGO:0030258840.139
response to nutrient levelsGO:0031667810.139
Rat Worm
polysaccharide metabolic processGO:0005976330.137
Human
fatty acid metabolic processGO:00066311150.136
positive regulation of smooth muscle cell migrationGO:001491160.135
nuclear transportGO:00511691790.135
Worm
regulation of mitotic cell cycleGO:00073461890.135
Human Mouse
positive regulation of cellular component organizationGO:00511303760.134
Human Mouse
somatic muscle developmentGO:000752510.134
Fly
positive regulation of protein localization to nucleusGO:1900182480.134
regulation of phosphatidylinositol 3 kinase activityGO:0043551140.133
positive regulation of cell projection organizationGO:0031346640.133
Human
regulation of leukocyte proliferationGO:0070663670.132
negative regulation of intracellular signal transductionGO:19025321830.131
positive regulation of cell differentiationGO:00455972110.129
Human
negative regulation of transmembrane transportGO:0034763290.128
regulation of axonogenesisGO:0050770160.126
regulation of golgi to plasma membrane protein transportGO:004299630.125
insulin secretionGO:0030073390.124
regulation of peptide transportGO:0090087620.124
positive regulation of glucose importGO:0046326160.123
Human
positive regulation of nitric oxide biosynthetic processGO:0045429130.121
Human
regulation of polysaccharide biosynthetic processGO:0032885200.121
Human
neuron projection developmentGO:00311751060.121
Human Rat Fly
positive regulation of cell developmentGO:0010720920.121
Human
negative regulation of transportGO:00510511760.120
Worm
regulation of stem cell proliferationGO:0072091150.120
regulation of autophagyGO:0010506520.120
Worm Fly
peptidyl tyrosine autophosphorylationGO:003808350.120
sodium ion transmembrane transportGO:0035725590.120
interleukin 12 mediated signaling pathwayGO:003572230.119
response to decreased oxygen levelsGO:0036293960.119
Fly
negative regulation of lipid transportGO:0032369180.119
multicellular organismal homeostasisGO:0048871670.118
regulation of translationGO:0006417890.118
response to oxidative stressGO:00069791210.118
Worm Fly
regulation of hydrogen peroxide metabolic processGO:001031060.118
rhythmic processGO:0048511310.117
Fly
negative regulation of protein metabolic processGO:00512483910.117
response to extracellular stimulusGO:0009991850.117
Rat Worm
single organism nuclear importGO:19025931040.116
Worm
regulation of insulin receptor signaling pathwayGO:0046626130.115
regulation of neuron projection developmentGO:0010975570.115
Human
single organism reproductive processGO:0044702980.115
Zebrafish Mouse Worm Fly
embryonic placenta developmentGO:000189210.113
growthGO:00400072020.112
Human Zebrafish Worm Fly
protein maturationGO:00516042330.112
Zebrafish

IGF1R disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
hyperinsulinemic hypoglycemiaDOID:1331771.000
Human
disease of metabolismDOID:00146672951.000
Human
carbohydrate metabolic disorderDOID:2978551.000
Human
inherited metabolic disorderDOID:6552421.000
Human
diabetes mellitusDOID:9351310.952
type 2 diabetes mellitusDOID:9352280.952
carbohydrate metabolism diseaseDOID:0050013320.952
glucose metabolism diseaseDOID:4194320.952
acquired metabolic diseaseDOID:0060158580.952
cancerDOID:1621670.842
disease of cellular proliferationDOID:145661740.842
organ system cancerDOID:00506861640.842
immune system cancerDOID:0060083360.276
hematologic cancerDOID:2531360.276
myeloid leukemiaDOID:8692180.123
acute myeloid leukemiaDOID:9119170.123
leukemiaDOID:1240210.123