Homo sapiens

70 known processes

LIN28B

lin-28 homolog B (C. elegans)

(Aliases: CSDD2,FLJ16517)

LIN28B biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
gene silencing by mirnaGO:0035195230.353
embryonic epithelial tube formationGO:000183840.281
regulation of neural precursor cell proliferationGO:200017740.264
cellular macromolecule catabolic processGO:00442653800.250
primary neural tube formationGO:001402030.219
regulation of viral processGO:00507921030.215
regulation of viral transcriptionGO:0046782340.207
multi organism metabolic processGO:0044033410.205
negative regulation of viral processGO:0048525660.199
multi organism cellular processGO:00447641560.184
protein modification by small protein conjugationGO:00324463420.171
symbiosis encompassing mutualism through parasitismGO:00444031560.168
protein ubiquitinationGO:00165673140.164
cellular protein catabolic processGO:00442572610.164
viral life cycleGO:00190581320.153
protein polyubiquitinationGO:00002091100.149
cellular response to dna damage stimulusGO:00069743790.147
viral processGO:00160321460.143
mitotic cell cycle phase transitionGO:00447721620.141
ncrna metabolic processGO:00346601080.138
response to fibroblast growth factorGO:0071774390.137
regulation of cell motilityGO:20001452990.136
regulation of cell cycleGO:00517263930.134
tube closureGO:006060630.131
positive regulation of nf kappab transcription factor activityGO:0051092810.126
negative regulation of viral release from host cellGO:1902187120.125
proteolysis involved in cellular protein catabolic processGO:00516032440.123
cell cycle phase transitionGO:00447701730.123
regulation of symbiosis encompassing mutualism through parasitismGO:00439031090.122
interspecies interaction between organismsGO:00444191560.118
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.118
negative regulation of cell deathGO:00605483450.116
regulation of cellular component movementGO:00512703340.115
positive regulation of proteolysisGO:00458621420.115
negative regulation of cellular protein metabolic processGO:00322693530.114
negative regulation of multi organism processGO:0043901920.112
cellular response to endogenous stimulusGO:00714953360.112
protein autoubiquitinationGO:0051865370.111
cellular response to fibroblast growth factor stimulusGO:0044344390.110
viral release from host cellGO:0019076210.109
positive regulation of i kappab kinase nf kappab signalingGO:00431231320.108
innate immune responseGO:00450871780.106
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.106
modification dependent protein catabolic processGO:00199412090.106
modification dependent macromolecule catabolic processGO:00436322120.105
regulation of locomotionGO:00400123290.105
viral gene expressionGO:0019080350.105
negative regulation of apoptotic processGO:00430663160.105
anatomical structure formation involved in morphogenesisGO:00486462840.104
ubiquitin dependent protein catabolic processGO:00065112060.104
regulation of translationGO:0006417890.103
translationGO:00064121320.101
protein catabolic processGO:00301633250.101
regulation of proteolysisGO:00301622930.099
i kappab kinase nf kappab signalingGO:00072491660.098
defense responseGO:00069523150.096
regulation of multi organism processGO:00439001570.095
regulation of cellular response to stressGO:00801352440.093
regulation of sequence specific dna binding transcription factor activityGO:00510902110.093
negative regulation of programmed cell deathGO:00430693210.092
positive regulation of cell motilityGO:20001471770.090
regulation of viral release from host cellGO:1902186200.090
regulation of i kappab kinase nf kappab signalingGO:00431221620.089
negative regulation of viral transcriptionGO:0032897230.086
proteasomal protein catabolic processGO:00104981760.085
apoptotic signaling pathwayGO:00971902680.084
regulation of cell migrationGO:00303342890.083
posttranscriptional gene silencing by rnaGO:0035194250.083
fibroblast growth factor receptor signaling pathwayGO:0008543260.081
enzyme linked receptor protein signaling pathwayGO:00071673030.081
nervous system developmentGO:00073992930.080
mitotic cell cycleGO:00002783260.079
mirna metabolic processGO:0010586100.078
post embryonic developmentGO:000979120.076
epithelial tube morphogenesisGO:0060562380.076
positive regulation of cell cycleGO:00457871400.074
regulation of apoptotic signaling pathwayGO:20012331750.073
cellular response to growth factor stimulusGO:00713631970.070
epithelium developmentGO:00604292270.070
immune responseGO:00069553070.067
mitotic cell cycle processGO:19030472860.067
negative regulation of apoptotic signaling pathwayGO:2001234970.065
regulation of intrinsic apoptotic signaling pathwayGO:2001242720.065
viral transcriptionGO:0019083350.064
positive regulation of cellular component movementGO:00512721810.064
positive regulation of locomotionGO:00400171860.063
positive regulation of cell migrationGO:00303351720.063
regulation of cell growthGO:00015581350.062
g1 s transition of mitotic cell cycleGO:0000082780.061
intrinsic apoptotic signaling pathwayGO:00971931270.060
response to growth factorGO:00708482050.059
negative regulation of intracellular signal transductionGO:19025321830.052
tube morphogenesisGO:0035239950.052
amine metabolic processGO:0009308440.050
cellular amino acid metabolic processGO:00065201160.050
tube developmentGO:00352951250.049
regulation of cellular amine metabolic processGO:0033238110.048
tissue morphogenesisGO:0048729960.048
regulation of gene expression epigeneticGO:0040029730.048
growthGO:00400072020.046
posttranscriptional gene silencingGO:0016441250.046
cellular amine metabolic processGO:0044106410.046
negative regulation of protein metabolic processGO:00512483910.044
cell growthGO:00160491600.044
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630500.042
gene silencingGO:0016458490.042
positive regulation of cellular amino acid metabolic processGO:004576430.040
cellular ketone metabolic processGO:0042180800.040
multicellular organismal agingGO:001025930.040
regulation of cellular amino acid metabolic processGO:000652160.039
locomotory behaviorGO:000762610.039
determination of adult lifespanGO:000834020.038
neuromuscular junction developmentGO:000752830.038
negative regulation of response to dna damage stimulusGO:2001021330.037
regulation of cellular ketone metabolic processGO:0010565500.037
posttranscriptional regulation of gene expressionGO:00106082130.036
positive regulation of cell growthGO:0030307480.034
negative regulation of intrinsic apoptotic signaling pathwayGO:2001243400.034
cell cycle g1 s phase transitionGO:0044843800.033
female gamete generationGO:000729220.032
oogenesisGO:004847720.031
negative regulation of translationGO:0017148370.031
positive regulation of cellular amine metabolic processGO:003324070.031
positive regulation of cellular component organizationGO:00511303760.031
regulation of gene silencingGO:0060968240.031
chromatin organizationGO:00063253510.030
negative regulation of catalytic activityGO:00430863350.030
positive regulation of developmental processGO:00510943140.029
segmentationGO:003528240.029
chromatin modificationGO:00165682980.028
regenerationGO:003109940.028
regulation of transferase activityGO:00513383550.028
rna processingGO:00063962550.028
system processGO:00030083490.027
covalent chromatin modificationGO:00165692540.027
cytoplasmic transportGO:00164823790.027
histone modificationGO:00165702510.026
embryo developmentGO:00097901230.026
positive regulation of hydrolase activityGO:00513453310.026
purine nucleoside triphosphate metabolic processGO:00091444120.025
transmembrane transportGO:00550853990.024
purine ribonucleoside triphosphate metabolic processGO:00092054110.024
organophosphate catabolic processGO:00464344300.024
positive regulation of transportGO:00510503360.024
lipid metabolic processGO:00066293810.024
chemical homeostasisGO:00488783060.024
biological adhesionGO:00226103310.023
glycosyl compound catabolic processGO:19016584130.023
single organism cellular localizationGO:19025803320.023
ras protein signal transductionGO:0007265730.023
actin filament based processGO:00300292240.023
purine ribonucleoside metabolic processGO:00461284370.023
ion transmembrane transportGO:00342203380.023
small gtpase mediated signal transductionGO:0007264780.023
protein maturationGO:00516042330.022
regulation of cell cycle processGO:00105642660.022
nucleoside triphosphate metabolic processGO:00091414220.022
ribonucleoside triphosphate catabolic processGO:00092033910.022
dna repairGO:00062811980.022
response to abiotic stimulusGO:00096283360.022
anterior posterior axis specificationGO:000994820.022
nucleoside phosphate catabolic processGO:19012924120.022
mapk cascadeGO:00001652880.021
secretionGO:00469032540.021
nucleoside triphosphate catabolic processGO:00091433940.021
single organism membrane organizationGO:00448022680.021
morphogenesis of embryonic epitheliumGO:001633140.021
positive regulation of programmed cell deathGO:00430682490.021
memoryGO:000761330.021
ribonucleoside triphosphate metabolic processGO:00091994120.021
purine containing compound catabolic processGO:00725234110.021
purine nucleotide catabolic processGO:00061954050.021
nucleotide catabolic processGO:00091664080.021
purine ribonucleoside triphosphate catabolic processGO:00092073910.021
adult locomotory behaviorGO:000834410.021
cellular lipid metabolic processGO:00442553030.020
ribonucleoside catabolic processGO:00424544060.020
positive regulation of catabolic processGO:00098963100.020
positive regulation of apoptotic processGO:00430652460.020
inorganic ion transmembrane transportGO:00986602310.020
ion homeostasisGO:00508012300.020
ribonucleotide catabolic processGO:00092614050.020
purine ribonucleotide catabolic processGO:00091544040.020
negative regulation of phosphorus metabolic processGO:00105632670.020
positive regulation of protein phosphorylationGO:00019343130.020
protein processingGO:00164852260.020
positive regulation of cell proliferationGO:00082843010.020
response to axon injuryGO:004867810.020
cellular component morphogenesisGO:00329893140.020
negative regulation of cell proliferationGO:00082852280.020
cell fate determinationGO:000170930.020
lipid biosynthetic processGO:00086101770.020
vesicle mediated transportGO:00161923710.020
axon regenerationGO:003110310.019
metal ion transportGO:00300012720.019
startle responseGO:000196430.019
protein localization to organelleGO:00333652800.019
negative regulation of protein modification processGO:00314002000.019
negative regulation of cellular amine metabolic processGO:003323930.019
purine nucleoside triphosphate catabolic processGO:00091463920.019
rho protein signal transductionGO:0007266260.019
organonitrogen compound biosynthetic processGO:19015662000.019
cell morphogenesisGO:00009022960.019
positive regulation of phosphorylationGO:00423273940.019
positive regulation of cell deathGO:00109422630.019
secretion by cellGO:00329402260.019
positive regulation of cellular catabolic processGO:00313312840.019
regulation of protein localizationGO:00328802960.019
regulation of protein kinase activityGO:00458592890.019
spermatid differentiationGO:004851540.019
dephosphorylationGO:00163112090.019
membrane organizationGO:00610242920.019
regulation of response to external stimulusGO:00321012220.019
response to external biotic stimulusGO:00432072610.019
cellular macromolecular complex assemblyGO:00346223240.019
negative regulation of cell cycleGO:00457861930.019
negative regulation of developmental processGO:00510932470.019
Human
circulatory system developmentGO:00723592620.019
negative regulation of cellular component organizationGO:00511292350.018
regulation of kinase activityGO:00435493140.018
negative regulation of multicellular organismal processGO:00512413170.018
carbohydrate derivative biosynthetic processGO:19011372070.018
purine nucleoside catabolic processGO:00061523980.018
nucleoside catabolic processGO:00091644080.018
nitrogen compound transportGO:00717051910.018
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.018
response to oxygen containing compoundGO:19017003690.018
purine ribonucleoside catabolic processGO:00461303980.018
response to other organismGO:00517072610.018
neurotransmitter secretionGO:000726940.018
maintenance of locationGO:00512351120.018
cell projection organizationGO:00300302520.018
compound eye developmentGO:004874910.018
negative regulation of phosphate metabolic processGO:00459362670.018
oocyte developmentGO:004859910.018
regulation of nucleotide metabolic processGO:00061402690.018
positive regulation of growthGO:0045927580.018
negative regulation of cellular amino acid metabolic processGO:004576320.017
intracellular protein transportGO:00068862700.017
cellular response to organic cyclic compoundGO:00714071270.017
cation transportGO:00068123310.017
cation homeostasisGO:00550801890.017
motor neuron axon guidanceGO:000804520.017
neurological system processGO:00508771630.017
cellular response to oxygen containing compoundGO:19017012760.017
organ formationGO:004864530.017
blastoderm segmentationGO:000735020.017
release of cytoplasmic sequestered nf kappabGO:000858840.017
cation transmembrane transportGO:00986552380.017
associative learningGO:000830610.017
regulation of protein transportGO:00512232130.017
cell developmentGO:00484683280.017
Human
positive regulation of cell differentiationGO:00455972110.017
cardiac muscle cell contractionGO:008600340.017
positive regulation of transferase activityGO:00513472270.017
oocyte differentiationGO:000999420.017
reactive oxygen species biosynthetic processGO:190340940.017
photoreceptor cell differentiationGO:004653020.017
hindbrain developmentGO:003090230.017
neuron projection regenerationGO:003110210.017
regulation of cell developmentGO:00602841610.016
regulation of anatomical structure morphogenesisGO:00226032860.016
regulation of cell cycle phase transitionGO:19019871260.016
regulation of cytokine productionGO:00018172320.016
small molecule biosynthetic processGO:00442831570.016
regulation of secretionGO:00510461940.016
rhythmic behaviorGO:000762220.016
regulation of establishment of protein localizationGO:00702012420.016
regulation of secretion by cellGO:19035301770.016
anion transportGO:00068201610.016
carbohydrate metabolic processGO:00059752070.016
regulation of purine nucleotide metabolic processGO:19005422640.016
cellular chemical homeostasisGO:00550821800.016
regulation of protein processingGO:00706131500.016
regulation of protein catabolic processGO:00421761550.016
regulation of dna metabolic processGO:00510521530.016
nerve developmentGO:002167540.016
peripheral nervous system developmentGO:000742220.016
cellular homeostasisGO:00197251960.016
inorganic cation transmembrane transportGO:00986621940.016
protein targetingGO:00066051870.016
regulation of cellular component biogenesisGO:00440872810.016
circadian behaviorGO:004851220.016
detection of stimulusGO:0051606850.016
signal transduction by phosphorylationGO:00230142970.016
positive regulation of synaptic transmissionGO:005080640.015
spermatid developmentGO:000728640.015
metal ion homeostasisGO:00550651690.015
regulation of mapk cascadeGO:00434082620.015
neuron differentiationGO:00301821380.015
negative regulation of hydrolase activityGO:00513461820.015
response to fungusGO:000962040.015
negative regulation of cell differentiationGO:00455961710.015
Human
limbic system developmentGO:002176130.015
positive regulation of immune system processGO:00026842830.015
positive regulation of organelle organizationGO:00106381950.015
reactive nitrogen species metabolic processGO:200105730.015
neural tube formationGO:000184130.015
positive regulation of purine nucleotide metabolic processGO:19005442270.015
oxidation reduction processGO:00551143960.015
spinal cord developmentGO:002151040.015
inner ear morphogenesisGO:004247240.015
regulation of cell differentiationGO:00455953930.015
Human
metencephalon developmentGO:002203720.015
specification of organ identityGO:001009230.015
cellular cation homeostasisGO:00300031630.015
neural crest cell developmentGO:001403230.015
response to biotic stimulusGO:00096072760.015
cell proliferation in forebrainGO:002184610.015
central nervous system developmentGO:00074171230.015
regulation of endopeptidase activityGO:00525481700.015
response to nitrogen compoundGO:19016981840.015
nuclear transportGO:00511691790.015
matingGO:000761810.015
regulation of mitotic cell cycleGO:00073461890.015
organophosphate biosynthetic processGO:00904071630.015
regulation of mitotic cell cycle phase transitionGO:19019901180.015
muscle contractionGO:0006936730.015
regulation of reactive oxygen species biosynthetic processGO:190342630.014
rna interferenceGO:001624640.014
cardiovascular system developmentGO:00723582620.014
positive regulation of gene silencing by mirnaGO:200063730.014
tripartite regional subdivisionGO:000735120.014
mrna metabolic processGO:00160711750.014
positive regulation of nucleotide metabolic processGO:00459812300.014
tissue regenerationGO:004224630.014
cell adhesionGO:00071553250.014
negative regulation of protein processingGO:00109551420.014
negative regulation of protein maturationGO:19033181420.014
positive regulation of nucleoside metabolic processGO:00459791860.014
cell divisionGO:00513011680.014
regulation of synaptic plasticityGO:004816730.014
neuron remodelingGO:001632220.014
regulation of intracellular transportGO:00323861950.014
response to woundingGO:00096111680.014
response to lipidGO:00339932060.014
cerebellum developmentGO:002154920.014
regulation of membrane potentialGO:0042391950.014
endomembrane system organizationGO:00102561960.014
organelle assemblyGO:00709251760.014
single organism carbohydrate metabolic processGO:00447231930.014
stem cell proliferationGO:0072089250.014
regulation of cytoplasmic transportGO:19036491490.014
regulation of meiotic cell cycleGO:005144540.014
negative regulation of phosphorylationGO:00423261740.014
guanosine containing compound metabolic processGO:19010682440.014
cytokine productionGO:00018162470.014
reactive oxygen species metabolic processGO:0072593750.013
response to radiationGO:00093141510.013
negative regulation of proteolysisGO:00458611320.013
response to cytokineGO:00340972320.013
actin mediated cell contractionGO:0070252120.013
regulation of hormone levelsGO:00108171250.013
regulation of purine nucleotide catabolic processGO:00331212050.013
regulation of cytoskeleton organizationGO:00514931770.013
protein deubiquitinationGO:0016579790.013
atp metabolic processGO:00460341760.013
regulation of peptidase activityGO:00525471800.013
ribonucleoside monophosphate metabolic processGO:00091611870.013
visual behaviorGO:000763220.013
gtp catabolic processGO:00061842370.013
cellular response to cytokine stimulusGO:00713451810.013
sensory perception of smellGO:000760820.013
guanosine containing compound catabolic processGO:19010692390.013
negative regulation of transportGO:00510511760.013
angiogenesisGO:00015251470.013
nucleoside monophosphate metabolic processGO:00091231910.013
protein modification by small protein removalGO:0070646920.013
establishment of protein localization to organelleGO:00725941720.013
negative regulation of cell cycle processGO:00109481210.013
purine nucleoside monophosphate metabolic processGO:00091261860.013
regulation of protein maturationGO:19033171500.013
negative regulation of organelle organizationGO:00106391260.013
positive regulation of cytokine productionGO:00018191670.013
forebrain generation of neuronsGO:002187230.013
purine ribonucleoside monophosphate metabolic processGO:00091671860.013
positive regulation of purine nucleotide catabolic processGO:00331231850.013
alcohol metabolic processGO:00060661140.013
syncytium formation by plasma membrane fusionGO:000076820.013
regulation of nucleoside metabolic processGO:00091182090.013
cellular ion homeostasisGO:00068731680.013
anion transmembrane transportGO:0098656760.013
regulation of protein serine threonine kinase activityGO:00719001790.013
neuroblast proliferationGO:000740540.013
protein acylationGO:00435431380.013
positive regulation of kinase activityGO:00336742040.013
mitochondrion organizationGO:00070051560.013
regulation of neuron projection regenerationGO:007057010.013
microtubule based processGO:00070172100.013
actin filament based movementGO:0030048170.013
cellular metal ion homeostasisGO:00068751460.013
negative regulation of transferase activityGO:00513481240.013
anterior posterior axis specification embryoGO:000859520.012
regulation of cell projection organizationGO:00313441070.012
positive regulation of mapk cascadeGO:00434101900.012
morphogenesis of a polarized epitheliumGO:000173830.012
head developmentGO:00603221080.012
forebrain neuron differentiationGO:002187930.012
nucleic acid phosphodiester bond hydrolysisGO:00903051020.012
cell cycle checkpointGO:00000751170.012
response to organic cyclic compoundGO:00140702040.012
positive regulation of reactive oxygen species biosynthetic processGO:190342820.012
establishment or maintenance of bipolar cell polarityGO:006124520.012
monocarboxylic acid metabolic processGO:00327871850.012
regulation of nucleotide catabolic processGO:00308112050.012
protein oligomerizationGO:00512591730.012
cell cell signalingGO:00072671550.012
regulation of vesicle mediated transportGO:00606271300.012
positive regulation of nucleotide catabolic processGO:00308131850.012
somatic stem cell maintenanceGO:003501940.012
actin cytoskeleton organizationGO:00300362070.012
sequestering of metal ionGO:0051238240.012
ossificationGO:00015031210.012
salivary gland morphogenesisGO:000743540.012
cellular response to nitrogen compoundGO:19016991440.012
monovalent inorganic cation transportGO:00156721280.012
carboxylic acid biosynthetic processGO:0046394970.012
establishment of planar polarityGO:000173630.012
divalent inorganic cation homeostasisGO:00725071360.012
cellular protein complex assemblyGO:00436231880.012
protein localization to membraneGO:00726571600.012
muscle system processGO:0003012810.012
positive regulation of acrosome reactionGO:200034440.012
single organism cell adhesionGO:00986021790.012
blood vessel morphogenesisGO:00485141620.012
striated muscle contractionGO:0006941520.012
organic hydroxy compound metabolic processGO:19016151470.012
regulation of immune responseGO:00507762010.012
regulation of ion transportGO:00432691890.012
organelle fissionGO:00482851490.012
blood vessel developmentGO:00015681720.012
positive regulation of secretionGO:00510471160.012
negative regulation of catabolic processGO:00098951040.012
neurogenesisGO:00220081690.012
negative regulation of gliogenesisGO:001401430.012
sex determinationGO:000753030.011
myoblast fusionGO:000752010.011
gtp metabolic processGO:00460392390.011
positive regulation of cell cycle processGO:00900681060.011
lung alveolus developmentGO:004828640.011
positive regulation of protein kinase activityGO:00458601900.011
sequestering of calcium ionGO:0051208170.011
meiosis iGO:000712740.011
neural tube closureGO:000184330.011
epithelial cell proliferationGO:00506731280.011
establishment or maintenance of apical basal cell polarityGO:003508820.011
epithelial cell differentiationGO:00308551410.011
glycoprotein metabolic processGO:00091001100.011
divalent inorganic cation transportGO:00725111580.011
microtubule cytoskeleton organizationGO:00002261760.011
regulation of growthGO:00400081650.011
organic acid biosynthetic processGO:0016053970.011
g protein coupled receptor signaling pathwayGO:00071862070.011
immune system developmentGO:00025201950.011
regulation of intrinsic apoptotic signaling pathway in response to dna damageGO:1902229200.011
cell projection assemblyGO:00300311260.011
stem cell divisionGO:001714520.011
endodermal cell fate commitmentGO:000171140.011
regulation of cell adhesionGO:00301551660.011
regulation of intracellular protein transportGO:00331571230.011
regulation of reactive oxygen species metabolic processGO:2000377410.011
retinal ganglion cell axon guidanceGO:003129020.011
nucleocytoplasmic transportGO:00069131760.011
regulation of meiosisGO:004002030.011
response to virusGO:00096151260.011
meiotic chromosome segregationGO:004513240.011
somitogenesisGO:000175620.011
response to organonitrogen compoundGO:00102431560.011
dna conformation changeGO:00711031130.011
fatty acid metabolic processGO:00066311150.011
wnt signaling pathwayGO:00160551560.011
regulation of ras protein signal transductionGO:00465781550.011

LIN28B disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:00146672950.027
sensory system diseaseDOID:00501552030.024
nervous system diseaseDOID:8634310.024
musculoskeletal system diseaseDOID:172230.023
inherited metabolic disorderDOID:6552420.022
cancerDOID:1621670.021
disease of cellular proliferationDOID:145661740.021
organ system cancerDOID:00506861640.020
eye diseaseDOID:56141490.019
eye and adnexa diseaseDOID:14921500.019
central nervous system diseaseDOID:3311860.017
retinal diseaseDOID:56791180.015
connective tissue diseaseDOID:651090.014
immune system diseaseDOID:29141550.013
bone diseaseDOID:0080001880.013
muscle tissue diseaseDOID:661130.013
muscular diseaseDOID:00800001140.013
neurodegenerative diseaseDOID:12891020.012
myopathyDOID:4231040.012
cardiovascular system diseaseDOID:12871060.011
brain diseaseDOID:936730.011