Homo sapiens

189 known processes

HMGB2

high mobility group box 2

(Aliases: HMG2)

HMGB2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
negative regulation of transcription initiation from rna polymerase ii promoterGO:006063331.000
Human
negative regulation of rna polymerase ii transcriptional preinitiation complex assemblyGO:001705520.935
Human
base excision repair dna ligationGO:000628820.769
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280690.584
Human
mitotic cell cycle processGO:19030472860.568
positive regulation of hydrolase activityGO:00513453310.443
rna polymerase ii transcriptional preinitiation complex assemblyGO:005112340.443
Human
regulation of cell differentiationGO:00455953930.430
regulation of proteolysisGO:00301622930.404
Human
regulation of nuclease activityGO:0032069110.353
nucleosome assemblyGO:0006334500.312
response to lipidGO:00339932060.305
v d j recombinationGO:003315130.254
Human
microtubule cytoskeleton organizationGO:00002261760.252
dna repairGO:00062811980.251
nucleosome organizationGO:0034728660.241
positive regulation of programmed cell deathGO:00430682490.231
Human
positive regulation of endopeptidase activityGO:0010950840.228
Human
positive regulation of proteolysisGO:00458621420.226
Human
regulation of cell cycleGO:00517263930.217
positive regulation of cysteine type endopeptidase activityGO:2001056790.214
Human
cellular response to dna damage stimulusGO:00069743790.213
dna ligation involved in dna repairGO:005110340.213
regulation of hematopoietic progenitor cell differentiationGO:1901532240.199
positive regulation of nuclease activityGO:003207550.189
positive regulation of peptidase activityGO:0010952880.184
Human
regulation of triglyceride catabolic processGO:001089660.178
dna packagingGO:0006323770.177
negative regulation of cellular component organizationGO:00511292350.174
Human
mitotic cell cycleGO:00002783260.166
mitotic cell cycle phase transitionGO:00447721620.157
regulation of megakaryocyte differentiationGO:0045652220.145
taxisGO:00423301570.144
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.140
Human
histone exchangeGO:004348630.138
asymmetric neuroblast divisionGO:005505910.136
positive regulation of transportGO:00510503360.132
positive regulation of cell deathGO:00109422630.128
Human
regulation of wnt signaling pathwayGO:00301111230.118
cellular amino acid metabolic processGO:00065201160.113
regulation of endopeptidase activityGO:00525481700.113
Human
regulation of mitotic cell cycleGO:00073461890.111
positive regulation of apoptotic processGO:00430652460.104
Human
neuroblast proliferationGO:000740540.102
negative regulation of cell differentiationGO:00455961710.099
positive regulation of homeostatic processGO:0032846470.098
regulation of response to dna damage stimulusGO:2001020940.097
neuroblast divisionGO:005505710.097
cellular response to oxygen containing compoundGO:19017012760.095
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.093
Human
nervous system developmentGO:00073992930.093
Rat
regulation of cysteine type endopeptidase activityGO:20001161270.091
Human
amine metabolic processGO:0009308440.091
chemotaxisGO:00069351570.090
positive regulation of cell proliferationGO:00082843010.084
response to lipopolysaccharideGO:0032496700.084
chromatin assembly or disassemblyGO:0006333780.082
dna conformation changeGO:00711031130.082
single organism cellular localizationGO:19025803320.081
regulation of endothelial cell proliferationGO:0001936560.081
negative regulation of cell cycleGO:00457861930.079
regulation of dna metabolic processGO:00510521530.079
Rat
response to other organismGO:00517072610.077
response to molecule of bacterial originGO:0002237820.077
somatic stem cell divisionGO:004810310.076
regulation of cell cycle processGO:00105642660.075
chromatin assemblyGO:0031497610.075
meiotic chromosome segregationGO:004513240.074
positive regulation of cell cycleGO:00457871400.074
positive regulation of wnt signaling pathwayGO:0030177540.074
g1 s transition of mitotic cell cycleGO:0000082780.073
maintenance of locationGO:00512351120.072
regulation of canonical wnt signaling pathwayGO:0060828880.072
cellular response to molecule of bacterial originGO:0071219620.072
mrna processingGO:00063971330.071
positive regulation of phosphorylationGO:00423273940.071
mitotic sister chromatid segregationGO:0000070530.070
canonical wnt signaling pathwayGO:00600701160.070
regulation of protein localizationGO:00328802960.069
regulation of cellular response to stressGO:00801352440.067
regulation of dna templated transcription initiationGO:200014290.067
Human
erythrocyte differentiationGO:0030218280.066
regulation of epithelial cell proliferationGO:00506781130.065
negative regulation of developmental processGO:00510932470.065
regulation of cytoplasmic transportGO:19036491490.064
response to bacteriumGO:00096171440.064
mitotic nuclear divisionGO:00070671190.064
inflammatory response to antigenic stimulusGO:000243740.063
Human
protein dna complex subunit organizationGO:0071824800.061
Human
neutral lipid catabolic processGO:0046461120.061
positive regulation of hematopoietic progenitor cell differentiationGO:190153450.061
neurogenesisGO:00220081690.060
protein processingGO:00164852260.060
hematopoietic progenitor cell differentiationGO:0002244380.059
oocyte developmentGO:004859910.058
oocyte differentiationGO:000999420.057
cellular response to lipopolysaccharideGO:0071222570.056
regulation of peptidase activityGO:00525471800.056
Human
positive regulation of epithelial cell proliferationGO:0050679650.056
chromatin remodelingGO:0006338550.056
organelle assemblyGO:00709251760.056
negative regulation of protein complex assemblyGO:0031333430.055
Human
immune system developmentGO:00025201950.054
positive regulation of protein transportGO:00512221350.054
response to abiotic stimulusGO:00096283360.054
rna processingGO:00063962550.054
positive regulation of cellular catabolic processGO:00313312840.054
immune responseGO:00069553070.054
Human
single organism reproductive processGO:0044702980.053
Mouse
cardiovascular system developmentGO:00723582620.053
cell chemotaxisGO:00603261120.053
positive regulation of cell differentiationGO:00455972110.052
base excision repairGO:0006284210.051
establishment of organelle localizationGO:0051656590.051
positive regulation of cytoplasmic transportGO:1903651820.050
asymmetric stem cell divisionGO:009872210.050
wnt signaling pathwayGO:00160551560.050
meiosis iGO:000712740.049
regulation of transcription initiation from rna polymerase ii promoterGO:006026080.049
Human
response to oxygen containing compoundGO:19017003690.049
hemopoiesisGO:00300971800.049
positive regulation of cellular component organizationGO:00511303760.049
oogenesisGO:004847720.048
positive regulation of intracellular transportGO:00323881040.047
transcription initiation from rna polymerase ii promoterGO:0006367270.047
Human
myeloid cell homeostasisGO:0002262340.046
generation of neuronsGO:00486991520.046
cell developmentGO:00484683280.044
Mouse
endomembrane system organizationGO:00102561960.044
regulation of cellular component biogenesisGO:00440872810.044
Human
microtubule based processGO:00070172100.044
negative regulation of dna templated transcription initiationGO:200014330.043
Human
reproductive processGO:00224141060.043
Mouse
purine ribonucleoside metabolic processGO:00461284370.043
post embryonic developmentGO:000979120.043
positive regulation of cell cycle processGO:00900681060.043
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434710.042
positive regulation of nucleocytoplasmic transportGO:0046824540.042
organelle fissionGO:00482851490.042
intracellular protein transportGO:00068862700.042
regulation of myeloid cell differentiationGO:0045637810.042
microtubule based movementGO:0007018320.042
regulation of cellular ketone metabolic processGO:0010565500.041
nuclear divisionGO:00002801280.041
organelle localizationGO:0051640840.041
regulation of nucleocytoplasmic transportGO:0046822980.041
dna templated transcription initiationGO:0006352350.041
Human
mitotic spindle organizationGO:0007052270.040
developmental process involved in reproductionGO:0003006660.040
Mouse
regulation of protein complex assemblyGO:00432541470.040
Human
negative regulation of chromosome organizationGO:2001251480.040
endothelial cell proliferationGO:0001935650.039
hematopoietic or lymphoid organ developmentGO:00485341860.039
regulation of protein transportGO:00512232130.039
response to external biotic stimulusGO:00432072610.039
regenerationGO:003109940.038
Rat
cellular macromolecule catabolic processGO:00442653800.037
spindle elongationGO:005123140.037
maintenance of protein location in cellGO:0032507560.037
cell cycle g1 s phase transitionGO:0044843800.037
protein export from nucleusGO:0006611290.036
positive regulation of mitotic cell cycleGO:0045931600.036
regulation of mitosisGO:0007088630.036
cellular response to fibroblast growth factor stimulusGO:0044344390.036
mesenchymal cell developmentGO:0014031500.036
positive regulation of intracellular protein transportGO:0090316760.036
ribonucleoside catabolic processGO:00424544060.035
golgi organizationGO:0007030380.035
regulation of cell divisionGO:00513021160.035
cellular component disassemblyGO:0022411920.034
neuron differentiationGO:00301821380.033
cellular amine metabolic processGO:0044106410.033
determination of adult lifespanGO:000834020.033
ras protein signal transductionGO:0007265730.033
stem cell divisionGO:001714520.033
protein dna complex assemblyGO:0065004640.033
Human
ribonucleoside triphosphate catabolic processGO:00092033910.033
protein complex disassemblyGO:0043241520.032
ribonucleotide catabolic processGO:00092614050.032
positive regulation of catabolic processGO:00098963100.032
cellular response to endogenous stimulusGO:00714953360.032
nuclear exportGO:0051168690.032
symbiosis encompassing mutualism through parasitismGO:00444031560.032
protein maturationGO:00516042330.032
enzyme linked receptor protein signaling pathwayGO:00071673030.032
regulation of cellular amine metabolic processGO:0033238110.032
female gamete generationGO:000729220.031
positive regulation of cell divisionGO:0051781590.031
positive regulation of dna bindingGO:0043388170.031
positive regulation of cellular amine metabolic processGO:003324070.031
regulation of cytoskeleton organizationGO:00514931770.030
regulation of establishment of protein localizationGO:00702012420.030
cell cycle phase transitionGO:00447701730.030
regulation of nuclear divisionGO:0051783650.030
methylationGO:00322591060.030
cofactor metabolic processGO:0051186870.029
embryo developmentGO:00097901230.029
negative regulation of organelle organizationGO:00106391260.029
reproductive system developmentGO:0061458560.029
Mouse
positive regulation of protein phosphorylationGO:00019343130.029
cellular macromolecular complex assemblyGO:00346223240.029
Human
glycosyl compound catabolic processGO:19016584130.028
protein localization to organelleGO:00333652800.028
microtubule organizing center organizationGO:0031023620.028
response to oxygen levelsGO:00704821000.028
tube developmentGO:00352951250.028
purine ribonucleoside catabolic processGO:00461303980.028
regulation of bindingGO:00510981110.027
blastocyst developmentGO:000182430.027
spindle assemblyGO:0051225290.027
nucleotide catabolic processGO:00091664080.027
nucleoside catabolic processGO:00091644080.027
cell divisionGO:00513011680.026
regulation of intracellular protein transportGO:00331571230.026
erythrocyte homeostasisGO:0034101310.026
regulation of intracellular transportGO:00323861950.026
posttranscriptional regulation of gene expressionGO:00106082130.026
negative regulation of cytoskeleton organizationGO:0051494450.026
somatic diversification of immune receptorsGO:000220080.026
Human
regulation of microtubule based processGO:0032886740.026
tissue regenerationGO:004224630.026
inflammatory responseGO:0006954790.026
Human
growthGO:00400072020.025
neuronal stem cell divisionGO:003644510.025
positive regulation of canonical wnt signaling pathwayGO:0090263330.025
dna ligationGO:0006266100.025
regulation of meiosisGO:004002030.025
chromatin modificationGO:00165682980.024
ribonucleoside monophosphate catabolic processGO:00091581580.024
negative regulation of protein complex disassemblyGO:0043242200.024
positive regulation of nucleotide metabolic processGO:00459812300.024
cell projection organizationGO:00300302520.024
regulation of nucleotide metabolic processGO:00061402690.024
locomotory behaviorGO:000762610.024
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.024
establishment or maintenance of cell polarityGO:0007163310.024
purine nucleoside catabolic processGO:00061523980.024
nucleoside triphosphate catabolic processGO:00091433940.024
positive regulation of bindingGO:0051099450.023
rna interferenceGO:001624640.023
activation of cysteine type endopeptidase activityGO:0097202570.023
activation of cysteine type endopeptidase activity involved in apoptotic processGO:0006919490.023
purine ribonucleoside triphosphate metabolic processGO:00092054110.023
maintenance of location in cellGO:0051651620.023
positive regulation of cellular protein catabolic processGO:1903364370.022
oxidation reduction processGO:00551143960.022
somatic muscle developmentGO:000752510.022
maintenance of protein locationGO:0045185570.022
negative regulation of protein modification processGO:00314002000.022
small gtpase mediated signal transductionGO:0007264780.022
regulation of proteasomal protein catabolic processGO:0061136870.022
rna splicingGO:00083801310.022
negative regulation of cell cycle phase transitionGO:1901988890.022
ameboidal type cell migrationGO:00016671350.022
cellular component morphogenesisGO:00329893140.022
chromosome segregationGO:00070591140.021
regulation of chromosome segregationGO:0051983440.021
regulation of cell growthGO:00015581350.021
segmentationGO:003528240.021
sister chromatid biorientationGO:003113420.021
system processGO:00030083490.021
regulation of mitotic cell cycle phase transitionGO:19019901180.021
sister chromatid segregationGO:0000819540.021
nucleoside phosphate catabolic processGO:19012924120.021
regulation of double strand break repairGO:2000779220.021
negative regulation of microtubule polymerization or depolymerizationGO:0031111170.021
positive regulation of proteasomal protein catabolic processGO:1901800350.021
regulation of cellular amino acid metabolic processGO:000652160.020
macromolecular complex disassemblyGO:0032984600.020
cellular protein catabolic processGO:00442572610.020
brain developmentGO:0007420970.020
zymogen activationGO:0031638700.020
regulation of histone h3 k27 methylationGO:006108540.020
proteasomal protein catabolic processGO:00104981760.020
negative regulation of cell cycle processGO:00109481210.020
gmp metabolic processGO:004603740.020
positive chemotaxisGO:0050918330.020
positive regulation of myeloid cell differentiationGO:0045639390.020
defense response to fungusGO:005083240.020
viral life cycleGO:00190581320.020
spindle organizationGO:0007051530.020
regulation of multi organism processGO:00439001570.019
negative regulation of dna metabolic processGO:0051053570.019
positive regulation of developmental processGO:00510943140.019
cellular response to biotic stimulusGO:0071216710.019
nucleoside monophosphate catabolic processGO:00091251590.019
nucleocytoplasmic transportGO:00069131760.019
regulation of homeostatic processGO:00328441210.019
protein methylationGO:0006479740.019
guanosine containing compound metabolic processGO:19010682440.019
purine nucleoside triphosphate metabolic processGO:00091444120.019
positive regulation of organelle organizationGO:00106381950.018
regulation of dephosphorylationGO:0035303960.018
centrosome organizationGO:0051297580.018
response to decreased oxygen levelsGO:0036293960.018
central nervous system developmentGO:00074171230.018
negative regulation of catalytic activityGO:00430863350.018
intracellular mrna localizationGO:000829810.018
microtubule polymerization or depolymerizationGO:0031109370.018
regulation of ras protein signal transductionGO:00465781550.018
regulation of microtubule cytoskeleton organizationGO:0070507610.018
purine ribonucleoside triphosphate catabolic processGO:00092073910.018
cell cycle arrestGO:0007050710.018
regulation of protein catabolic processGO:00421761550.018
organophosphate catabolic processGO:00464344300.018
atp dependent chromatin remodelingGO:0043044250.017
neural tube closureGO:000184330.017
regulation of cellular protein catabolic processGO:1903362960.017
anatomical structure formation involved in morphogenesisGO:00486462840.017
multi organism reproductive processGO:0044703540.017
Mouse
reproductionGO:0000003630.017
Mouse
cellular response to hormone stimulusGO:00328701250.017
regulation of small gtpase mediated signal transductionGO:00510561560.017
regulation of transferase activityGO:00513383550.017
response to fungusGO:000962040.017
positive regulation of nucleotide catabolic processGO:00308131850.017
response to cytokineGO:00340972320.017
spindle assembly involved in mitosisGO:0090307120.017
establishment or maintenance of microtubule cytoskeleton polarityGO:003095120.017
apoptotic signaling pathwayGO:00971902680.017
Mouse
purine containing compound catabolic processGO:00725234110.016
regulation of rna polymerase ii transcriptional preinitiation complex assemblyGO:004589830.016
Human
spermatid developmentGO:000728640.016
Mouse
nuclear transportGO:00511691790.016
regulation of purine nucleotide metabolic processGO:19005422640.016
regulation of cell cycle phase transitionGO:19019871260.016
response to hormoneGO:00097251750.016
Mouse
cytoplasmic transportGO:00164823790.016
positive regulation of nucleoside metabolic processGO:00459791860.016
response to alcoholGO:0097305640.016
purine nucleotide catabolic processGO:00061954050.016
cell morphogenesis involved in differentiationGO:00009041440.016
histone serine phosphorylationGO:003540440.016
neuron developmentGO:00486661130.016
regulation of dna repairGO:0006282470.016
protein depolymerizationGO:0051261300.015
dna replicationGO:00062601160.015
cytokinesisGO:0000910960.015
mrna splicing via spliceosomeGO:0000398890.015
response to growth factorGO:00708482050.015
head developmentGO:00603221080.015
pharynx developmentGO:006046510.015
regulation of dna bindingGO:0051101370.015
regulation of meiotic cell cycleGO:005144540.015
cellular ketone metabolic processGO:0042180800.015
cell part morphogenesisGO:00329901370.015
circulatory system developmentGO:00723592620.015
positive regulation of protein catabolic processGO:0045732750.014
rna splicing via transesterification reactionsGO:0000375900.014
tripartite regional subdivisionGO:000735120.014
regulation of mrna metabolic processGO:1903311530.014
purine nucleoside triphosphate catabolic processGO:00091463920.014
ubiquitin dependent protein catabolic processGO:00065112060.014
response to activityGO:001482300.014
protein catabolic processGO:00301633250.014
protein import into nucleusGO:00066061040.014
regulation of proteolysis involved in cellular protein catabolic processGO:1903050910.014
regulation of protein export from nucleusGO:0046825150.014
cell morphogenesisGO:00009022960.014
regulation of gene silencingGO:0060968240.014
behaviorGO:00076101120.014
neural crest cell developmentGO:001403230.014
establishment or maintenance of cytoskeleton polarityGO:003095230.014
positive regulation of immune system processGO:00026842830.014
neurological system processGO:00508771630.014
interspecies interaction between organismsGO:00444191560.013
negative regulation of mitotic cell cycleGO:00459301020.013
chromosome condensationGO:0030261150.013
response to axon injuryGO:004867810.013
neuromuscular junction developmentGO:000752830.013
ribonucleoside triphosphate metabolic processGO:00091994120.013
negative regulation of intracellular signal transductionGO:19025321830.013
cellular response to cytokine stimulusGO:00713451810.013
regulation of mrna processingGO:0050684480.013
proteolysis involved in cellular protein catabolic processGO:00516032440.013
cellular response to oxidative stressGO:0034599850.013
mrna metabolic processGO:00160711750.013
regulation of nucleoside metabolic processGO:00091182090.013
regulation of protein targetingGO:1903533910.013
cell fate determinationGO:000170930.013
peptidyl serine phosphorylationGO:00181051010.013
modification dependent protein catabolic processGO:00199412090.013
response to oxidative stressGO:00069791210.013
positive regulation of proteolysis involved in cellular protein catabolic processGO:1903052350.013
stem cell differentiationGO:0048863930.013
regulation of microtubule polymerization or depolymerizationGO:0031110270.013
nucleoside triphosphate metabolic processGO:00091414220.013
sex differentiationGO:0007548450.013
Mouse
fertilizationGO:0009566120.013
organ morphogenesisGO:00098871470.012
positive regulation of purine nucleotide catabolic processGO:00331231850.012
cellular response to growth factor stimulusGO:00713631970.012
guanosine containing compound catabolic processGO:19010692390.012
mesenchyme developmentGO:0060485590.012
positive regulation of cellular amino acid metabolic processGO:004576430.012
positive regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032436300.012
establishment of nucleus localizationGO:004002310.012
gene silencingGO:0016458490.012
protein localization to chromosomeGO:0034502300.012
negative regulation of apoptotic processGO:00430663160.012
Mouse
negative regulation of mitotic metaphase anaphase transitionGO:0045841170.011
mitotic spindle elongationGO:000002240.011
negative regulation of ligase activityGO:005135280.011
cellular response to decreased oxygen levelsGO:0036294510.011
regulation of spindle organizationGO:0090224100.011
modification dependent macromolecule catabolic processGO:00436322120.011
regulation of kinase activityGO:00435493140.011
anterior posterior axis specificationGO:000994820.011
protein acetylationGO:00064731160.011
regulation of protein processingGO:00706131500.011
internal protein amino acid acetylationGO:00064751010.011
peptidyl lysine modificationGO:00182051440.011
primary neural tube formationGO:001402030.011
mesenchymal cell differentiationGO:0048762520.011
histone h3 s10 phosphorylationGO:004398730.011
centrosome separationGO:005129930.011
positive regulation of endothelial cell proliferationGO:0001938370.011
negative regulation of cell deathGO:00605483450.011
Mouse
regulation of mrna splicing via spliceosomeGO:0048024320.010
multicellular organism reproductionGO:0032504420.010
Mouse
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.010
centrosome cycleGO:0007098320.010
development of primary sexual characteristicsGO:0045137350.010
Mouse
response to biotic stimulusGO:00096072760.010
nitrogen compound transportGO:00717051910.010
establishment of ribosome localizationGO:003375340.010
atp catabolic processGO:00062001570.010
negative regulation of dephosphorylationGO:0035305630.010

HMGB2 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:00146672950.054
inherited metabolic disorderDOID:6552420.048