Homo sapiens

22 known processes

TGM1

transglutaminase 1 (K polypeptide epidermal type I, protein-glutamine-gamma-glutamyltransferase)

(Aliases: TGASE,LI,LI1,ICR2,TGK,KTG)

TGM1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
hepoxilin metabolic processGO:005112110.482
lipoxin b4 metabolic processGO:200130410.316
hepoxilin biosynthetic processGO:005112210.269
lipoxygenase pathwayGO:001937240.222
epidermis morphogenesisGO:004873030.199
leukotriene a4 metabolic processGO:190175110.175
skin developmentGO:0043588760.148
positive regulation of phosphorylationGO:00423273940.138
regulation of locomotionGO:00400123290.128
cellular ketone metabolic processGO:0042180800.110
amine metabolic processGO:0009308440.105
cellular amine metabolic processGO:0044106410.103
positive regulation of cellular amine metabolic processGO:003324070.100
regulation of cellular component movementGO:00512703340.098
epidermis developmentGO:0008544590.096
linoleic acid metabolic processGO:004365140.095
small gtpase mediated signal transductionGO:0007264780.093
regulation of anatomical structure morphogenesisGO:00226032860.092
cellular amino acid metabolic processGO:00065201160.088
regulation of cell differentiationGO:00455953930.087
regulation of cell migrationGO:00303342890.086
positive regulation of cell proliferationGO:00082843010.081
regulation of mapk cascadeGO:00434082620.079
lipid metabolic processGO:00066293810.077
epithelium developmentGO:00604292270.077
negative regulation of apoptotic processGO:00430663160.077
positive regulation of mapk cascadeGO:00434101900.076
mapk cascadeGO:00001652880.075
regulation of cellular amino acid metabolic processGO:000652160.075
actin filament based processGO:00300292240.074
purine ribonucleoside metabolic processGO:00461284370.071
regulation of cellular amine metabolic processGO:0033238110.071
positive regulation of cell motilityGO:20001471770.070
positive regulation of cellular amino acid metabolic processGO:004576430.069
post embryonic developmentGO:000979120.067
regulation of cell motilityGO:20001452990.066
anatomical structure formation involved in morphogenesisGO:00486462840.064
regulation of cellular ketone metabolic processGO:0010565500.064
regulation of cytokine productionGO:00018172320.062
ribonucleoside triphosphate catabolic processGO:00092033910.062
cytoplasmic transportGO:00164823790.061
positive regulation of locomotionGO:00400171860.061
small molecule biosynthetic processGO:00442831570.060
keratinizationGO:003142420.059
cellular lipid metabolic processGO:00442553030.058
nucleotide catabolic processGO:00091664080.058
defense responseGO:00069523150.057
positive regulation of immune system processGO:00026842830.057
cardiovascular system developmentGO:00723582620.056
locomotory behaviorGO:000762610.054
purine nucleoside catabolic processGO:00061523980.054
regulation of protein localizationGO:00328802960.053
positive regulation of cell migrationGO:00303351720.052
response to cytokineGO:00340972320.052
purine ribonucleoside catabolic processGO:00461303980.051
chemical homeostasisGO:00488783060.051
Human
cellular response to cytokine stimulusGO:00713451810.051
signal transduction by phosphorylationGO:00230142970.051
copulationGO:000762010.051
cellular component morphogenesisGO:00329893140.051
positive regulation of developmental processGO:00510943140.050
immune responseGO:00069553070.050
ribonucleotide catabolic processGO:00092614050.049
ribonucleoside triphosphate metabolic processGO:00091994120.049
ras protein signal transductionGO:0007265730.049
negative regulation of programmed cell deathGO:00430693210.049
hair follicle morphogenesisGO:003106920.048
matingGO:000761810.048
organophosphate catabolic processGO:00464344300.048
ribonucleoside catabolic processGO:00424544060.048
cytokine productionGO:00018162470.048
regulation of gtp catabolic processGO:00331241800.047
response to biotic stimulusGO:00096072760.047
purine ribonucleoside triphosphate metabolic processGO:00092054110.047
cell developmentGO:00484683280.046
blood vessel developmentGO:00015681720.046
positive regulation of cellular component movementGO:00512721810.046
nucleoside triphosphate catabolic processGO:00091433940.045
ameboidal type cell migrationGO:00016671350.045
positive regulation of protein phosphorylationGO:00019343130.045
cell morphogenesisGO:00009022960.044
purine ribonucleotide catabolic processGO:00091544040.044
divalent inorganic cation homeostasisGO:00725071360.044
Human
blood vessel morphogenesisGO:00485141620.044
cell adhesionGO:00071553250.044
protein processingGO:00164852260.043
nucleoside triphosphate metabolic processGO:00091414220.043
negative regulation of cell proliferationGO:00082852280.042
negative regulation of cell deathGO:00605483450.042
positive regulation of transportGO:00510503360.042
purine nucleoside triphosphate metabolic processGO:00091444120.042
response to oxygen containing compoundGO:19017003690.042
nucleoside catabolic processGO:00091644080.041
growthGO:00400072020.041
regulation of nucleoside metabolic processGO:00091182090.041
glycosyl compound catabolic processGO:19016584130.041
gtp catabolic processGO:00061842370.041
inseminationGO:000732010.040
lipid biosynthetic processGO:00086101770.040
seminal clot liquefactionGO:007068410.040
epithelial cell migrationGO:00106311190.039
purine nucleotide catabolic processGO:00061954050.039
system processGO:00030083490.039
regulation of gtpase activityGO:00430871800.039
innate immune responseGO:00450871780.039
positive regulation of hydrolase activityGO:00513453310.039
regulation of actin filament based processGO:00329701410.039
purine nucleoside triphosphate catabolic processGO:00091463920.039
cardiac muscle cell contractionGO:008600340.039
long chain fatty acid metabolic processGO:0001676300.038
regenerationGO:003109940.038
vesicle mediated transportGO:00161923710.038
Human
oxidation reduction processGO:00551143960.038
carboxylic acid biosynthetic processGO:0046394970.038
purine ribonucleoside triphosphate catabolic processGO:00092073910.037
regulation of purine nucleotide catabolic processGO:00331212050.037
negative regulation of cellular protein metabolic processGO:00322693530.037
negative regulation of multicellular organismal processGO:00512413170.037
guanosine containing compound catabolic processGO:19010692390.037
response to external biotic stimulusGO:00432072610.037
nucleoside phosphate catabolic processGO:19012924120.037
rho protein signal transductionGO:0007266260.036
biological adhesionGO:00226103310.036
regulation of purine nucleotide metabolic processGO:19005422640.036
regulation of nucleotide metabolic processGO:00061402690.036
organic acid biosynthetic processGO:0016053970.036
positive regulation of nucleoside metabolic processGO:00459791860.036
positive regulation of cytokine productionGO:00018191670.035
calcium ion homeostasisGO:00550741220.035
Human
single organism cellular localizationGO:19025803320.034
protein maturationGO:00516042330.034
monocarboxylic acid metabolic processGO:00327871850.034
regulation of sequence specific dna binding transcription factor activityGO:00510902110.034
segmentationGO:003528240.034
positive regulation of nucleotide catabolic processGO:00308131850.033
positive regulation of secretionGO:00510471160.033
actin cytoskeleton organizationGO:00300362070.033
purine containing compound catabolic processGO:00725234110.033
multicellular organismal agingGO:001025930.033
enzyme linked receptor protein signaling pathwayGO:00071673030.033
secretionGO:00469032540.033
guanosine containing compound metabolic processGO:19010682440.033
leukotriene metabolic processGO:0006691100.032
positive regulation of cell differentiationGO:00455972110.032
epithelial cell proliferationGO:00506731280.032
positive regulation of erk1 and erk2 cascadeGO:0070374750.031
organ morphogenesisGO:00098871470.031
regulation of nucleotide catabolic processGO:00308112050.031
fatty acid metabolic processGO:00066311150.031
response to abiotic stimulusGO:00096283360.031
regulation of cell cycleGO:00517263930.031
response to lipidGO:00339932060.031
regulation of cell growthGO:00015581350.031
positive regulation of purine nucleotide metabolic processGO:19005442270.031
cellular macromolecular complex assemblyGO:00346223240.031
positive regulation of catabolic processGO:00098963100.030
cell activationGO:00017752130.030
regulation of growthGO:00400081650.030
positive regulation of gtp catabolic processGO:00331261660.030
response to organic cyclic compoundGO:00140702040.030
gtp metabolic processGO:00460392390.030
vasculature developmentGO:00019441810.030
determination of adult lifespanGO:000834020.030
regulation of protein transportGO:00512232130.030
regulation of kinase activityGO:00435493140.030
positive regulation of purine nucleotide catabolic processGO:00331231850.029
regulation of small gtpase mediated signal transductionGO:00510561560.029
cell growthGO:00160491600.029
epithelial cell differentiationGO:00308551410.029
membrane organizationGO:00610242920.029
angiogenesisGO:00015251470.029
defense response to other organismGO:00985421290.029
regulation of transferase activityGO:00513383550.028
circulatory system developmentGO:00723592620.028
organic hydroxy compound metabolic processGO:19016151470.028
response to inorganic substanceGO:00100351270.028
tissue migrationGO:00901301190.028
response to other organismGO:00517072610.027
nervous system developmentGO:00073992930.027
positive regulation of protein transportGO:00512221350.027
ion homeostasisGO:00508012300.027
Human
memoryGO:000761330.027
regulation of establishment of protein localizationGO:00702012420.027
hair cycleGO:0042633280.027
arachidonic acid metabolic processGO:0019369140.027
positive regulation of cellular catabolic processGO:00313312840.027
cell fate determinationGO:000170930.027
positive regulation of nucleotide metabolic processGO:00459812300.027
positive regulation of gtpase activityGO:00435471660.026
negative regulation of catalytic activityGO:00430863350.026
keratinocyte differentiationGO:0030216360.026
erk1 and erk2 cascadeGO:00703711040.026
peptidyl tyrosine modificationGO:00182121700.026
positive regulation of cytosolic calcium ion concentrationGO:0007204820.025
cellular metal ion homeostasisGO:00068751460.025
Human
regulation of proteolysisGO:00301622930.025
regulation of cell adhesionGO:00301551660.025
regulation of angiogenesisGO:0045765920.025
cellular response to oxygen containing compoundGO:19017012760.024
negative regulation of protein metabolic processGO:00512483910.024
regulation of secretionGO:00510461940.024
negative regulation of hydrolase activityGO:00513461820.024
neuromuscular junction developmentGO:000752830.024
single organism membrane organizationGO:00448022680.024
cellular response to dna damage stimulusGO:00069743790.024
regulation of response to external stimulusGO:00321012220.024
positive regulation of ras gtpase activityGO:00323201170.023
secretion by cellGO:00329402260.023
regulation of immune responseGO:00507762010.023
negative regulation of phosphorus metabolic processGO:00105632670.023
sequestering of metal ionGO:0051238240.023
epidermal cell differentiationGO:0009913450.023
zymogen activationGO:0031638700.023
regulation of cell developmentGO:00602841610.023
positive regulation of cellular component organizationGO:00511303760.023
unsaturated fatty acid metabolic processGO:0033559370.023
positive regulation of apoptotic processGO:00430652460.023
Human
monocarboxylic acid biosynthetic processGO:0072330670.023
maintenance of locationGO:00512351120.023
protein modification by small protein conjugationGO:00324463420.023
positive regulation of kinase activityGO:00336742040.023
actin mediated cell contractionGO:0070252120.023
regulation of protein kinase activityGO:00458592890.022
positive regulation of cell deathGO:00109422630.022
Human
regulation of cell morphogenesisGO:00226041530.022
regulation of cytoplasmic transportGO:19036491490.022
rhythmic behaviorGO:000762220.022
negative regulation of cell cycleGO:00457861930.022
positive regulation of transferase activityGO:00513472270.022
regulation of intracellular transportGO:00323861950.022
adult locomotory behaviorGO:000834410.022
wnt signaling pathwayGO:00160551560.022
posttranscriptional regulation of gene expressionGO:00106082130.022
cellular chemical homeostasisGO:00550821800.022
Human
positive regulation of sequence specific dna binding transcription factor activityGO:00510911310.021
regulation of body fluid levelsGO:0050878990.021
tissue regenerationGO:004224630.021
cation homeostasisGO:00550801890.021
Human
circadian behaviorGO:004851220.021
positive regulation of programmed cell deathGO:00430682490.021
Human
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.021
fatty acid derivative metabolic processGO:1901568350.021
regulation of erk1 and erk2 cascadeGO:0070372990.021
sequestering of calcium ionGO:0051208170.021
positive regulation of protein kinase activityGO:00458601900.020
mitotic cell cycleGO:00002783260.020
regulation of cellular component biogenesisGO:00440872810.020
epithelium migrationGO:00901321190.020
cellular cation homeostasisGO:00300031630.020
Human
mitotic cell cycle processGO:19030472860.020
positive regulation of secretion by cellGO:19035321080.020
cellular homeostasisGO:00197251960.020
Human
intracellular protein transportGO:00068862700.020
circulatory system processGO:00030131130.020
cell projection organizationGO:00300302520.020
organonitrogen compound biosynthetic processGO:19015662000.020
organic hydroxy compound biosynthetic processGO:1901617710.020
endomembrane system organizationGO:00102561960.020
protein catabolic processGO:00301633250.020
cell type specific apoptotic processGO:00972851250.020
associative learningGO:000830610.020
ion transmembrane transportGO:00342203380.019
regulation of cytoskeleton organizationGO:00514931770.019
leukocyte activationGO:00453211640.019
negative regulation of cellular amine metabolic processGO:003323930.019
regulation of cell cycle processGO:00105642660.019
chemotaxisGO:00069351570.019
response to fungusGO:000962040.019
chromatin organizationGO:00063253510.019
regulation of vasculature developmentGO:1901342970.019
metal ion homeostasisGO:00550651690.019
Human
negative regulation of cellular amino acid metabolic processGO:004576320.019
neurological system processGO:00508771630.019
regulation of ras gtpase activityGO:00323181280.018
cytokine secretionGO:0050663640.018
regulation of actin cytoskeleton organizationGO:00329561160.018
regulation of protein maturationGO:19033171500.018
calcium ion transportGO:00068161470.018
cellular protein complex assemblyGO:00436231880.018
taxisGO:00423301570.018
positive regulation of protein serine threonine kinase activityGO:00719021190.018
sex determinationGO:000753030.018
fatty acid biosynthetic processGO:0006633460.018
regulation of protein secretionGO:0050708860.018
endodermal cell fate commitmentGO:000171140.018
establishment of protein localization to membraneGO:00901501210.018
apoptotic signaling pathwayGO:00971902680.018
regulation of ras protein signal transductionGO:00465781550.018
long chain fatty acid biosynthetic processGO:004275940.018
embryonic forelimb morphogenesisGO:003511540.018
icosanoid metabolic processGO:0006690350.018
cellular ion homeostasisGO:00068731680.018
Human
action potentialGO:0001508340.018
regulation of secretion by cellGO:19035301770.018
oogenesisGO:004847720.018
regulation of cellular response to stressGO:00801352440.018
reactive oxygen species biosynthetic processGO:190340940.018
cellular macromolecule catabolic processGO:00442653800.017
positive regulation of insulin like growth factor receptor signaling pathwayGO:004356840.017
female gamete generationGO:000729220.017
tube developmentGO:00352951250.017
response to bacteriumGO:00096171440.017
positive regulation of immune responseGO:00507781590.017
forelimb morphogenesisGO:003513640.017
muscle contractionGO:0006936730.017
negative regulation of protein processingGO:00109551420.017
defense response to fungusGO:005083240.017
response to metal ionGO:0010038840.017
regulation of cytokine secretionGO:0050707570.017
endothelial cell migrationGO:0043542860.017
positive regulation of angiogenesisGO:0045766510.017
positive regulation of peptidyl tyrosine phosphorylationGO:0050731850.017
muscle system processGO:0003012810.016
regulation of i kappab kinase nf kappab signalingGO:00431221620.016
peripheral nervous system developmentGO:000742220.016
negative regulation of growthGO:0045926970.016
cellular protein catabolic processGO:00442572610.016
regulation of protein processingGO:00706131500.016
second messenger mediated signalingGO:0019932780.016
negative regulation of cellular component organizationGO:00511292350.016
protein localization to organelleGO:00333652800.016
organ formationGO:004864530.016
lymphocyte activationGO:00466491330.016
negative regulation of protein modification processGO:00314002000.016
hematopoietic or lymphoid organ developmentGO:00485341860.016
negative regulation of phosphate metabolic processGO:00459362670.016
regulation of peptidyl tyrosine phosphorylationGO:00507301080.016
regulation of multi organism processGO:00439001570.016
protein ubiquitinationGO:00165673140.016
peptidyl tyrosine phosphorylationGO:00181081700.016
immune effector processGO:00022521590.016
regulation of cell substrate adhesionGO:0010810680.016
response to woundingGO:00096111680.016
protein targetingGO:00066051870.016
positive regulation of intracellular transportGO:00323881040.016
regulation of epithelial cell proliferationGO:00506781130.016
regulation of defense responseGO:00313471540.016
transmembrane transportGO:00550853990.015
golgi to plasma membrane cftr protein transportGO:004300010.015
visual behaviorGO:000763220.015
cell divisionGO:00513011680.015
blastoderm segmentationGO:000735020.015
g protein coupled receptor signaling pathwayGO:00071862070.015
central nervous system developmentGO:00074171230.015
hindlimb morphogenesisGO:003513720.015
motor neuron axon guidanceGO:000804520.015
cellular divalent inorganic cation homeostasisGO:00725031280.015
Human
positive regulation of cellular component biogenesisGO:00440891580.015
regulation of protein serine threonine kinase activityGO:00719001790.015
negative regulation of protein maturationGO:19033181420.015
spermatid differentiationGO:004851540.015
dephosphorylationGO:00163112090.015
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781250.015
plasma membrane organizationGO:00070091150.015
nucleocytoplasmic transportGO:00069131760.015
positive regulation of organelle organizationGO:00106381950.015
inorganic cation transmembrane transportGO:00986621940.015
microtubule based processGO:00070172100.015
protein localization to membraneGO:00726571600.015
protein secretionGO:0009306980.015
nuclear transportGO:00511691790.015
single organismal cell cell adhesionGO:00163371480.015
reactive oxygen species metabolic processGO:0072593750.015
embryonic epithelial tube formationGO:000183840.015
protein oligomerizationGO:00512591730.015
Human
negative regulation of intracellular signal transductionGO:19025321830.014
positive regulation of cytoplasmic transportGO:1903651820.014
response to growth factorGO:00708482050.014
morphogenesis of embryonic epitheliumGO:001633140.014
organelle assemblyGO:00709251760.014
regulation of mitotic cell cycleGO:00073461890.014
proteolysis involved in cellular protein catabolic processGO:00516032440.014
negative regulation of developmental processGO:00510932470.014
covalent chromatin modificationGO:00165692540.014
response to oxidative stressGO:00069791210.014
regulation of reactive oxygen species biosynthetic processGO:190342630.014
ossificationGO:00015031210.014
chromatin modificationGO:00165682980.014
membrane lipid metabolic processGO:0006643530.014
regulation of apoptotic signaling pathwayGO:20012331750.014
single organism cell adhesionGO:00986021790.014
sensory perception of painGO:001923340.014
positive regulation of response to external stimulusGO:0032103880.014
regulation of ion transmembrane transporter activityGO:0032412720.014
lipid modificationGO:0030258840.014
spermatid developmentGO:000728640.014
regulation of dna metabolic processGO:00510521530.014
sensory perceptionGO:00076001030.014
response to radiationGO:00093141510.014
endocytosisGO:00068971590.014
Human
canonical wnt signaling pathwayGO:00600701160.014
regulation of intracellular protein transportGO:00331571230.014
negative regulation of peptidase activityGO:0010466910.014
negative regulation of protein phosphorylationGO:00019331400.013
regulation of endopeptidase activityGO:00525481700.013
nitrogen compound transportGO:00717051910.013
response to virusGO:00096151260.013
regulation of cell projection organizationGO:00313441070.013
metal ion transportGO:00300012720.013
negative regulation of proteolysisGO:00458611320.013
cytokine mediated signaling pathwayGO:00192211090.013
blood circulationGO:00080151130.013
cell substrate adhesionGO:00315891320.013
regulation of protein catabolic processGO:00421761550.013
lens development in camera type eyeGO:000208820.013
thymus developmentGO:004853830.013
cell morphogenesis involved in differentiationGO:00009041440.013
cellular response to growth factor stimulusGO:00713631970.013
regulation of odontogenesisGO:004248140.013
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.013
negative regulation of catabolic processGO:00098951040.013
anterior posterior axis specificationGO:000994820.013
unsaturated fatty acid biosynthetic processGO:0006636210.013
negative regulation of immune system processGO:00026831360.013
regulation of peptidase activityGO:00525471800.013
positive regulation of protein secretionGO:0050714600.013
carbohydrate derivative biosynthetic processGO:19011372070.013
cell cell signalingGO:00072671550.013
modification dependent macromolecule catabolic processGO:00436322120.013
compound eye developmentGO:004874910.013
tube morphogenesisGO:0035239950.013
regulation of g protein coupled receptor protein signaling pathwayGO:0008277350.013
oocyte developmentGO:004859910.013
activation of immune responseGO:00022531140.013
fatty acid derivative biosynthetic processGO:1901570180.013
reactive nitrogen species metabolic processGO:200105730.013
endoderm formationGO:0001706330.013
response to hormoneGO:00097251750.012
divalent inorganic cation transportGO:00725111580.012
regulation of transmembrane transporter activityGO:0022898740.012
dna repairGO:00062811980.012
phospholipid metabolic processGO:0006644990.012
regulation of synaptic plasticityGO:004816730.012
neurotransmitter secretionGO:000726940.012
regulation of reactive oxygen species metabolic processGO:2000377410.012
cell cycle phase transitionGO:00447701730.012
specification of organ identityGO:001009230.012
cytosolic calcium ion homeostasisGO:0051480890.012
multi organism cellular processGO:00447641560.012
negative regulation of transportGO:00510511760.012
regulation of wnt signaling pathwayGO:00301111230.012
regulation of protein stabilityGO:0031647870.012
positive regulation of cell growthGO:0030307480.012
i kappab kinase nf kappab signalingGO:00072491660.012
regulation of cell activationGO:00508651250.012
cellular component assembly involved in morphogenesisGO:0010927730.012
negative regulation of phosphorylationGO:00423261740.012
regulation of cell morphogenesis involved in differentiationGO:0010769830.012
response to axon injuryGO:004867810.012
morphogenesis of an epitheliumGO:0002009600.012
histone modificationGO:00165702510.012
negative regulation of androgen biosynthetic processGO:200018010.012
defense response to bacteriumGO:0042742630.012
regulation of leukocyte activationGO:00026941150.012
cell part morphogenesisGO:00329901370.012
negative regulation of gliogenesisGO:001401430.012
hormone metabolic processGO:0042445610.012
tissue morphogenesisGO:0048729960.012
cellular response to metal ionGO:0071248430.012
cell projection assemblyGO:00300311260.012
protein acylationGO:00435431380.012
muscle cell fate commitmentGO:004269340.012
syncytium formation by plasma membrane fusionGO:000076820.012
mitotic cell cycle phase transitionGO:00447721620.012
negative regulation of cell differentiationGO:00455961710.012
regulation of symbiosis encompassing mutualism through parasitismGO:00439031090.012
positive regulation of reactive oxygen species biosynthetic processGO:190342820.012
somatic stem cell maintenanceGO:003501940.012
negative regulation of organelle organizationGO:00106391260.012
extrinsic apoptotic signaling pathwayGO:00971911190.012
cellular amide metabolic processGO:0043603690.012
regulation of ion transportGO:00432691890.012
positive regulation of proteolysisGO:00458621420.012
modification dependent protein catabolic processGO:00199412090.012
regulation of cysteine type endopeptidase activityGO:20001161270.012

TGM1 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
sensory system diseaseDOID:00501552030.052
nervous system diseaseDOID:8634310.052
musculoskeletal system diseaseDOID:172230.027
eye and adnexa diseaseDOID:14921500.022
eye diseaseDOID:56141490.022
retinal diseaseDOID:56791180.018
immune system diseaseDOID:29141550.017
Human
connective tissue diseaseDOID:651090.016
disease of metabolismDOID:00146672950.016
disease of cellular proliferationDOID:145661740.016
organ system cancerDOID:00506861640.016
cancerDOID:1621670.016
bone diseaseDOID:0080001880.014
retinal degenerationDOID:8466890.014
central nervous system diseaseDOID:3311860.014
cardiovascular system diseaseDOID:12871060.013
muscular diseaseDOID:00800001140.012
integumentary system diseaseDOID:16430.012