Homo sapiens

6 known processes

INPP5E

inositol polyphosphate-5-phosphatase, 72 kDa

(Aliases: PPI5PIV,JBTS1,MORMS,CORS1,CPD4,MGC117201)

INPP5E biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
small gtpase mediated signal transductionGO:0007264780.084
regulation of cellular amine metabolic processGO:0033238110.077
post embryonic developmentGO:000979120.071
regulation of cellular amino acid metabolic processGO:000652160.066
regulation of cellular ketone metabolic processGO:0010565500.062
amine metabolic processGO:0009308440.059
cellular amine metabolic processGO:0044106410.058
ribonucleoside triphosphate catabolic processGO:00092033910.057
glycosyl compound catabolic processGO:19016584130.057
ribonucleoside triphosphate metabolic processGO:00091994120.056
cellular ketone metabolic processGO:0042180800.055
cellular amino acid metabolic processGO:00065201160.054
purine nucleoside triphosphate metabolic processGO:00091444120.051
organophosphate catabolic processGO:00464344300.050
purine nucleoside catabolic processGO:00061523980.050
ras protein signal transductionGO:0007265730.048
nucleoside phosphate catabolic processGO:19012924120.044
regulation of nucleotide metabolic processGO:00061402690.044
purine ribonucleoside metabolic processGO:00461284370.044
nucleotide catabolic processGO:00091664080.044
purine nucleoside triphosphate catabolic processGO:00091463920.044
regulation of cell cycle processGO:00105642660.043
positive regulation of hydrolase activityGO:00513453310.042
positive regulation of cellular component organizationGO:00511303760.042
Rat
morphogenesis of embryonic epitheliumGO:001633140.040
purine ribonucleoside triphosphate metabolic processGO:00092054110.039
regulation of cell cycleGO:00517263930.039
purine ribonucleoside catabolic processGO:00461303980.039
positive regulation of purine nucleotide metabolic processGO:19005442270.039
positive regulation of catabolic processGO:00098963100.039
positive regulation of nucleotide metabolic processGO:00459812300.038
negative regulation of catalytic activityGO:00430863350.037
ribonucleoside catabolic processGO:00424544060.037
determination of adult lifespanGO:000834020.037
gtp metabolic processGO:00460392390.036
rab protein signal transductionGO:003248240.036
nucleoside triphosphate metabolic processGO:00091414220.036
purine ribonucleoside triphosphate catabolic processGO:00092073910.036
positive regulation of cellular amino acid metabolic processGO:004576430.035
negative regulation of protein metabolic processGO:00512483910.034
ribonucleotide catabolic processGO:00092614050.033
regulation of nucleotide catabolic processGO:00308112050.033
female gamete generationGO:000729220.033
chromatin organizationGO:00063253510.032
hindbrain developmentGO:003090230.032
multicellular organismal agingGO:001025930.031
nucleoside catabolic processGO:00091644080.031
positive regulation of cell deathGO:00109422630.031
positive regulation of cellular amine metabolic processGO:003324070.031
locomotory behaviorGO:000762610.031
positive regulation of purine nucleotide catabolic processGO:00331231850.030
regulation of nucleoside metabolic processGO:00091182090.030
regulation of gtpase activityGO:00430871800.030
cell projection organizationGO:00300302520.030
Rat
positive regulation of nucleoside metabolic processGO:00459791860.029
purine ribonucleotide catabolic processGO:00091544040.029
regulation of purine nucleotide metabolic processGO:19005422640.029
positive regulation of cellular catabolic processGO:00313312840.029
innate immune responseGO:00450871780.027
purine nucleotide catabolic processGO:00061954050.027
mitotic cell cycleGO:00002783260.027
positive regulation of programmed cell deathGO:00430682490.027
signal transduction by phosphorylationGO:00230142970.027
biological adhesionGO:00226103310.027
actin filament based processGO:00300292240.026
Human
neuromuscular junction developmentGO:000752830.026
regulation of cell differentiationGO:00455953930.026
Rat
cellular response to dna damage stimulusGO:00069743790.026
segmentationGO:003528240.026
rho protein signal transductionGO:0007266260.025
embryonic epithelial tube formationGO:000183840.025
cell adhesionGO:00071553250.025
positive regulation of apoptotic processGO:00430652460.025
nucleoside triphosphate catabolic processGO:00091433940.025
guanosine containing compound catabolic processGO:19010692390.025
regulation of transferase activityGO:00513383550.025
positive regulation of phosphorylationGO:00423273940.025
blastoderm segmentationGO:000735020.024
regulation of purine nucleotide catabolic processGO:00331212050.024
oogenesisGO:004847720.024
negative regulation of cellular amino acid metabolic processGO:004576320.024
negative regulation of cellular protein metabolic processGO:00322693530.024
covalent chromatin modificationGO:00165692540.024
regulation of cellular response to stressGO:00801352440.024
positive regulation of nucleotide catabolic processGO:00308131850.024
purine containing compound catabolic processGO:00725234110.024
positive regulation of cell differentiationGO:00455972110.024
Rat
regulation of kinase activityGO:00435493140.023
response to abiotic stimulusGO:00096283360.023
protein modification by small protein conjugationGO:00324463420.023
histone modificationGO:00165702510.023
regulation of small gtpase mediated signal transductionGO:00510561560.023
negative regulation of phosphate metabolic processGO:00459362670.022
positive regulation of gtpase activityGO:00435471660.022
positive regulation of protein phosphorylationGO:00019343130.022
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.022
nervous system developmentGO:00073992930.022
Rat
positive regulation of gtp catabolic processGO:00331261660.022
metencephalon developmentGO:002203720.022
cellular component morphogenesisGO:00329893140.022
vesicle mediated transportGO:00161923710.022
Human
neural tube formationGO:000184130.022
protein ubiquitinationGO:00165673140.022
regulation of gtp catabolic processGO:00331241800.021
system processGO:00030083490.021
defense responseGO:00069523150.021
neurogenesisGO:00220081690.021
Rat
cell morphogenesisGO:00009022960.021
response to external biotic stimulusGO:00432072610.021
regulation of ras gtpase activityGO:00323181280.021
cellular macromolecular complex assemblyGO:00346223240.021
internal protein amino acid acetylationGO:00064751010.020
microtubule based processGO:00070172100.020
mitotic cell cycle processGO:19030472860.020
compound eye developmentGO:004874910.020
protein acylationGO:00435431380.020
cellular macromolecule catabolic processGO:00442653800.020
single organism carbohydrate metabolic processGO:00447231930.020
cellular response to endogenous stimulusGO:00714953360.020
positive regulation of ras gtpase activityGO:00323201170.020
negative regulation of multicellular organismal processGO:00512413170.020
membrane organizationGO:00610242920.020
positive regulation of immune system processGO:00026842830.020
regulation of ras protein signal transductionGO:00465781550.020
protein catabolic processGO:00301633250.020
positive regulation of organelle organizationGO:00106381950.020
negative regulation of cellular amine metabolic processGO:003323930.019
regulation of protein localizationGO:00328802960.019
cell cycle phase transitionGO:00447701730.019
peptidyl lysine modificationGO:00182051440.019
guanosine containing compound metabolic processGO:19010682440.019
chromatin modificationGO:00165682980.019
negative regulation of phosphorus metabolic processGO:00105632670.019
positive regulation of immune responseGO:00507781590.019
mapk cascadeGO:00001652880.019
negative regulation of cell cycleGO:00457861930.019
primary neural tube formationGO:001402030.019
positive regulation of cell proliferationGO:00082843010.019
anterior posterior axis specificationGO:000994820.019
regulation of proteolysisGO:00301622930.019
regulation of protein kinase activityGO:00458592890.019
regulation of bindingGO:00510981110.018
positive regulation of developmental processGO:00510943140.018
Rat
regenerationGO:003109940.018
tripartite regional subdivisionGO:000735120.018
response to oxygen containing compoundGO:19017003690.018
regulation of immune responseGO:00507762010.018
regulation of neural precursor cell proliferationGO:200017740.018
negative regulation of protein modification processGO:00314002000.018
establishment of planar polarityGO:000173630.018
negative regulation of programmed cell deathGO:00430693210.018
regulation of mitotic cell cycleGO:00073461890.018
spermatid developmentGO:000728640.018
regulation of response to external stimulusGO:00321012220.018
organonitrogen compound biosynthetic processGO:19015662000.018
lipid metabolic processGO:00066293810.017
positive regulation of transferase activityGO:00513472270.017
transmembrane transportGO:00550853990.017
matingGO:000761810.017
carbohydrate derivative biosynthetic processGO:19011372070.017
negative regulation of cell deathGO:00605483450.017
peptidyl lysine acetylationGO:00183941010.017
regulation of mapk cascadeGO:00434082620.017
neural tube closureGO:000184330.017
negative regulation of developmental processGO:00510932470.017
carbohydrate metabolic processGO:00059752070.017
protein localization to organelleGO:00333652800.017
regulation of cellular component movementGO:00512703340.017
morphogenesis of a polarized epitheliumGO:000173830.017
cell part morphogenesisGO:00329901370.017
cytoplasmic transportGO:00164823790.017
apoptotic signaling pathwayGO:00971902680.016
anatomical structure formation involved in morphogenesisGO:00486462840.016
nitrogen compound transportGO:00717051910.016
spermatid differentiationGO:004851540.016
regulation of cell motilityGO:20001452990.016
startle responseGO:000196430.016
immune responseGO:00069553070.016
inner ear morphogenesisGO:004247240.016
response to other organismGO:00517072610.016
negative regulation of hydrolase activityGO:00513461820.016
neurotransmitter secretionGO:000726940.016
cation transportGO:00068123310.016
positive regulation of rab gtpase activityGO:0032851390.016
regulation of meiotic cell cycleGO:005144540.016
regulation of growthGO:00400081650.016
microtubule cytoskeleton organizationGO:00002261760.016
anion transportGO:00068201610.016
single organism membrane organizationGO:00448022680.016
regulation of peptidase activityGO:00525471800.016
regulation of sequence specific dna binding transcription factor activityGO:00510902110.016
neuron differentiationGO:00301821380.016
Rat
regulation of locomotionGO:00400123290.016
memoryGO:000761330.016
regulation of multi organism processGO:00439001570.015
protein acetylationGO:00064731160.015
proteasomal protein catabolic processGO:00104981760.015
negative regulation of growthGO:0045926970.015
posttranscriptional regulation of gene expressionGO:00106082130.015
establishment or maintenance of bipolar cell polarityGO:006124520.015
positive regulation of transportGO:00510503360.015
regulation of anatomical structure morphogenesisGO:00226032860.015
cellular lipid metabolic processGO:00442553030.015
organ formationGO:004864530.015
actin mediated cell contractionGO:0070252120.015
regulation of cell migrationGO:00303342890.015
protein oligomerizationGO:00512591730.015
growthGO:00400072020.015
cell morphogenesis involved in differentiationGO:00009041440.015
negative regulation of intracellular signal transductionGO:19025321830.015
histone h3 acetylationGO:0043966450.015
proteolysis involved in cellular protein catabolic processGO:00516032440.015
positive regulation of neural precursor cell proliferationGO:200017920.015
endosomal transportGO:00161971290.015
single organism cell adhesionGO:00986021790.015
mitotic cell cycle phase transitionGO:00447721620.014
cellular protein catabolic processGO:00442572610.014
anterior posterior axis specification embryoGO:000859520.014
positive regulation of synaptic transmissionGO:005080640.014
positive regulation of kinase activityGO:00336742040.014
cellular response to oxygen containing compoundGO:19017012760.014
regulation of protein serine threonine kinase activityGO:00719001790.014
cell projection morphogenesisGO:00488581290.014
neuroblast proliferationGO:000740540.014
secretion by cellGO:00329402260.014
dephosphorylationGO:00163112090.014
Rat
regulation of cell adhesionGO:00301551660.014
long term memoryGO:000761620.014
cell divisionGO:00513011680.014
cell fate determinationGO:000170930.014
neurological system processGO:00508771630.014
enzyme linked receptor protein signaling pathwayGO:00071673030.014
positive regulation of cell cycle processGO:00900681060.014
negative regulation of cell cycle processGO:00109481210.014
regulation of cytoskeleton organizationGO:00514931770.014
establishment or maintenance of epithelial cell apical basal polarityGO:004519710.014
cellular protein complex assemblyGO:00436231880.014
regulation of cell cycle phase transitionGO:19019871260.014
metal ion transportGO:00300012720.014
response to biotic stimulusGO:00096072760.014
negative regulation of phosphorylationGO:00423261740.014
protein autophosphorylationGO:00467771230.014
positive regulation of cell cycleGO:00457871400.014
regulation of establishment of protein localizationGO:00702012420.014
response to woundingGO:00096111680.014
endomembrane system organizationGO:00102561960.014
intracellular protein transportGO:00068862700.014
regulation of endopeptidase activityGO:00525481700.014
reactive oxygen species metabolic processGO:0072593750.014
organophosphate biosynthetic processGO:00904071630.013
cardiovascular system developmentGO:00723582620.013
chemical homeostasisGO:00488783060.013
peripheral nervous system developmentGO:000742220.013
ion transmembrane transportGO:00342203380.013
establishment of tissue polarityGO:000716430.013
associative learningGO:000830610.013
positive regulation of cell migrationGO:00303351720.013
modification dependent macromolecule catabolic processGO:00436322120.013
cell developmentGO:00484683280.013
Rat
glycoprotein metabolic processGO:00091001100.013
visual behaviorGO:000763220.013
positive regulation of cellular component movementGO:00512721810.013
epithelium developmentGO:00604292270.013
regulation of dna metabolic processGO:00510521530.013
negative regulation of cellular component organizationGO:00511292350.013
regulation of cysteine type endopeptidase activityGO:20001161270.013
actin filament based movementGO:0030048170.013
negative regulation of cell proliferationGO:00082852280.013
purine ribonucleoside monophosphate metabolic processGO:00091671860.013
response to fungusGO:000962040.013
negative regulation of mitotic cell cycleGO:00459301020.013
cellular homeostasisGO:00197251960.013
histone acetylationGO:0016573930.013
ribonucleoside monophosphate metabolic processGO:00091611870.013
secretionGO:00469032540.013
motor neuron axon guidanceGO:000804520.013
adult locomotory behaviorGO:000834410.013
response to virusGO:00096151260.013
positive regulation of cell motilityGO:20001471770.013
g protein coupled receptor signaling pathwayGO:00071862070.013
regulation of protein transportGO:00512232130.013
reactive nitrogen species metabolic processGO:200105730.013
meiotic chromosome segregationGO:004513240.013
cellular response to cytokine stimulusGO:00713451810.013
spinal cord developmentGO:002151040.013
regulation of response to dna damage stimulusGO:2001020940.013
regulation of protein stabilityGO:0031647870.013
oocyte developmentGO:004859910.013
central nervous system developmentGO:00074171230.013
mitochondrion organizationGO:00070051560.013
response to radiationGO:00093141510.013
forebrain neuron differentiationGO:002187930.012
regulation of synaptic plasticityGO:004816730.012
establishment or maintenance of apical basal cell polarityGO:003508820.012
somitogenesisGO:000175620.012
neuron projection developmentGO:00311751060.012
Rat
positive regulation of defense responseGO:0031349870.012
photoreceptor cell differentiationGO:004653020.012
protein localization to membraneGO:00726571600.012
positive regulation of proteolysisGO:00458621420.012
circulatory system developmentGO:00723592620.012
regulation of cellular component biogenesisGO:00440872810.012
forebrain generation of neuronsGO:002187230.012
rna processingGO:00063962550.012
regulation of mitotic cell cycle phase transitionGO:19019901180.012
activation of immune responseGO:00022531140.012
cerebellum developmentGO:002154920.012
positive regulation of peptidase activityGO:0010952880.012
protein methylationGO:0006479740.012
rhythmic behaviorGO:000762220.012
regulation of rab protein signal transductionGO:0032483390.012
salivary gland morphogenesisGO:000743540.012
protein maturationGO:00516042330.012
positive regulation of protein kinase activityGO:00458601900.012
negative regulation of axonogenesisGO:005077140.012
reactive oxygen species biosynthetic processGO:190340940.012
negative regulation of protein phosphorylationGO:00019331400.012
tube closureGO:006060630.012
regulation of secretionGO:00510461940.012
cell projection assemblyGO:00300311260.012
regulation of defense responseGO:00313471540.012
single organismal cell cell adhesionGO:00163371480.012
regulation of rab gtpase activityGO:0032313390.012
inorganic ion transmembrane transportGO:00986602310.012
maintenance of locationGO:00512351120.012
response to growth factorGO:00708482050.012
stress activated mapk cascadeGO:0051403930.012
generation of neuronsGO:00486991520.012
Rat
oocyte differentiationGO:000999420.012
single organism cellular localizationGO:19025803320.012
circadian behaviorGO:004851220.012
positive regulation of locomotionGO:00400171860.012
neuron fate commitmentGO:004866320.012
syncytium formation by plasma membrane fusionGO:000076820.011
neuron developmentGO:00486661130.011
Rat
defense response to virusGO:0051607710.011
negative regulation of apoptotic processGO:00430663160.011
cation transmembrane transportGO:00986552380.011
atp metabolic processGO:00460341760.011
somatic stem cell maintenanceGO:003501940.011
head developmentGO:00603221080.011
purine nucleoside monophosphate metabolic processGO:00091261860.011
negative regulation of transferase activityGO:00513481240.011
sex determinationGO:000753030.011
limbic system developmentGO:002176130.011
regulation of protein catabolic processGO:00421761550.011
protein targetingGO:00066051870.011
ubiquitin dependent protein catabolic processGO:00065112060.011
regulation of reactive oxygen species biosynthetic processGO:190342630.011
response to nitrogen compoundGO:19016981840.011
cell growthGO:00160491600.011
negative regulation of organelle organizationGO:00106391260.011
modification dependent protein catabolic processGO:00199412090.011
regulation of apoptotic signaling pathwayGO:20012331750.011
reproductive processGO:00224141060.011
chemotaxisGO:00069351570.011
organelle fissionGO:00482851490.011
glycerolipid metabolic processGO:00464861070.011
negative regulation of transportGO:00510511760.011
regulation of meiosisGO:004002030.011
macromolecule methylationGO:0043414970.011
positive regulation of i kappab kinase nf kappab signalingGO:00431231320.011
glial cell migrationGO:000834740.011
protein processingGO:00164852260.011
convergent extensionGO:006002610.011
brain developmentGO:0007420970.011
epithelial cell differentiationGO:00308551410.011
regulation of cytokine productionGO:00018172320.011
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.011
macromolecule deacylationGO:0098732410.011
visual learningGO:000854210.011
regulation of chromosome organizationGO:00330441030.011
i kappab kinase nf kappab signalingGO:00072491660.011
peptidyl tyrosine phosphorylationGO:00181081700.011
negative regulation of synaptic transmissionGO:005080520.011
regulation of i kappab kinase nf kappab signalingGO:00431221620.011
regulation of cell divisionGO:00513021160.010
regulation of cell morphogenesisGO:00226041530.010
sensory perception of painGO:001923340.010
positive regulation of cell developmentGO:0010720920.010
Rat
immune system developmentGO:00025201950.010
hemopoiesisGO:00300971800.010
defense response to other organismGO:00985421290.010
taxisGO:00423301570.010
inorganic cation transmembrane transportGO:00986621940.010
methylationGO:00322591060.010
mitotic nuclear divisionGO:00070671190.010
organic anion transportGO:00157111030.010
cellular response to nitrogen compoundGO:19016991440.010
response to axon injuryGO:004867810.010
hematopoietic or lymphoid organ developmentGO:00485341860.010
oxidation reduction processGO:00551143960.010
nucleoside monophosphate metabolic processGO:00091231910.010
organelle assemblyGO:00709251760.010
brain morphogenesisGO:004885410.010
small molecule biosynthetic processGO:00442831570.010
cranial nerve developmentGO:002154540.010
regulation of response to woundingGO:19030341010.010
immune effector processGO:00022521590.010
monovalent inorganic cation transportGO:00156721280.010

INPP5E disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
musculoskeletal system diseaseDOID:172230.029
nervous system diseaseDOID:8634310.023
central nervous system diseaseDOID:3311860.023
muscular diseaseDOID:00800001140.018
disease of metabolismDOID:00146672950.016
sensory system diseaseDOID:00501552030.016
muscle tissue diseaseDOID:661130.016
myopathyDOID:4231040.015
organ system cancerDOID:00506861640.013
disease of cellular proliferationDOID:145661740.013
cancerDOID:1621670.013
inherited metabolic disorderDOID:6552420.012
brain diseaseDOID:936730.011
connective tissue diseaseDOID:651090.011
eye and adnexa diseaseDOID:14921500.011
eye diseaseDOID:56141490.010
retinal diseaseDOID:56791180.010
bone diseaseDOID:0080001880.010
joubert syndromeDOID:0050777180.003