Homo sapiens

193 known processes

DNAJB6

DnaJ (Hsp40) homolog, subfamily B, member 6

(Aliases: FLJ42837,DJ4,MRJ,MGC1152,HSJ-2,HHDJ1,HSJ2,MSJ-1,DnaJ,DKFZp566D0824,MGC117297)

DNAJB6 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
protein refoldingGO:0042026140.589
Human
de novo protein foldingGO:000645820.306
determination of adult lifespanGO:000834020.228
de novo posttranslational protein foldingGO:005108420.172
nucleoside catabolic processGO:00091644080.159
actin filament based processGO:00300292240.143
Mouse
multicellular organismal agingGO:001025930.135
ribonucleoside catabolic processGO:00424544060.133
negative regulation of programmed cell deathGO:00430693210.130
chaperone cofactor dependent protein refoldingGO:007038940.122
modification dependent macromolecule catabolic processGO:00436322120.117
Human
post embryonic developmentGO:000979120.117
response to abiotic stimulusGO:00096283360.115
ubiquitin dependent protein catabolic processGO:00065112060.110
Human
cell developmentGO:00484683280.107
negative regulation of apoptotic processGO:00430663160.102
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.097
Human
regulation of purine nucleotide metabolic processGO:19005422640.096
positive regulation of apoptotic processGO:00430652460.095
intracellular protein transmembrane transportGO:0065002240.090
positive regulation of programmed cell deathGO:00430682490.090
cellular macromolecule catabolic processGO:00442653800.087
Human
purine ribonucleotide catabolic processGO:00091544040.085
membrane organizationGO:00610242920.081
cytoplasmic transportGO:00164823790.081
intracellular protein transportGO:00068862700.080
single organism membrane organizationGO:00448022680.078
regulation of protein transportGO:00512232130.078
purine ribonucleoside metabolic processGO:00461284370.077
posttranscriptional regulation of gene expressionGO:00106082130.076
negative regulation of cell deathGO:00605483450.076
female gamete generationGO:000729220.074
purine nucleoside triphosphate metabolic processGO:00091444120.073
cellular component morphogenesisGO:00329893140.072
cellular response to topologically incorrect proteinGO:0035967190.070
apoptotic signaling pathwayGO:00971902680.067
purine ribonucleoside triphosphate catabolic processGO:00092073910.067
modification dependent protein catabolic processGO:00199412090.066
Human
cell type specific apoptotic processGO:00972851250.066
regulation of jnk cascadeGO:0046328730.063
mitotic cell cycleGO:00002783260.063
defense responseGO:00069523150.063
positive regulation of hydrolase activityGO:00513453310.062
positive regulation of cellular catabolic processGO:00313312840.062
nervous system developmentGO:00073992930.062
rna interferenceGO:001624640.062
protein localization to membraneGO:00726571600.060
regulation of purine nucleotide catabolic processGO:00331212050.056
negative regulation of phosphate metabolic processGO:00459362670.056
purine nucleoside catabolic processGO:00061523980.056
response to topologically incorrect proteinGO:0035966290.054
negative regulation of phosphorylationGO:00423261740.053
positive regulation of nucleotide metabolic processGO:00459812300.052
stress activated mapk cascadeGO:0051403930.051
nucleoside phosphate catabolic processGO:19012924120.051
cellular macromolecular complex assemblyGO:00346223240.050
transmembrane transportGO:00550853990.049
regulation of nucleotide metabolic processGO:00061402690.049
regulation of protein modification by small protein conjugation or removalGO:19033201070.048
Human
oogenesisGO:004847720.048
ribonucleoside triphosphate catabolic processGO:00092033910.048
adult locomotory behaviorGO:000834410.047
negative regulation of phosphorus metabolic processGO:00105632670.046
purine containing compound catabolic processGO:00725234110.046
regulation of establishment of protein localizationGO:00702012420.046
ribonucleotide catabolic processGO:00092614050.046
ribonucleoside triphosphate metabolic processGO:00091994120.046
protein modification by small protein conjugationGO:00324463420.045
Human
regulation of nucleotide catabolic processGO:00308112050.045
regulation of cell cycleGO:00517263930.045
regulation of protein localizationGO:00328802960.044
cellular protein catabolic processGO:00442572610.044
Human
purine ribonucleoside triphosphate metabolic processGO:00092054110.044
gtp metabolic processGO:00460392390.044
guanosine containing compound metabolic processGO:19010682440.043
positive regulation of cell deathGO:00109422630.043
negative regulation of protein metabolic processGO:00512483910.043
neuromuscular junction developmentGO:000752830.042
nucleoside triphosphate catabolic processGO:00091433940.041
generation of neuronsGO:00486991520.041
multi organism cellular processGO:00447641560.041
cellular protein complex assemblyGO:00436231880.041
regulation of nucleoside metabolic processGO:00091182090.040
regulation of transferase activityGO:00513383550.040
negative regulation of cellular component organizationGO:00511292350.039
locomotory behaviorGO:000762610.039
endosomal transportGO:00161971290.039
negative regulation of cellular protein metabolic processGO:00322693530.039
protein polyubiquitinationGO:00002091100.039
chromatin organizationGO:00063253510.039
negative regulation of protein modification processGO:00314002000.039
Human
positive regulation of catabolic processGO:00098963100.038
negative regulation of cell cycleGO:00457861930.038
establishment of protein localization to membraneGO:00901501210.037
nucleotide catabolic processGO:00091664080.037
actin cytoskeleton organizationGO:00300362070.037
Mouse
proteolysis involved in cellular protein catabolic processGO:00516032440.037
Human
regulation of kinase activityGO:00435493140.036
positive regulation of cellular amino acid metabolic processGO:004576430.036
nucleoside triphosphate metabolic processGO:00091414220.036
regulation of cellular component biogenesisGO:00440872810.036
positive regulation of purine nucleotide metabolic processGO:19005442270.035
cellular component assembly involved in morphogenesisGO:0010927730.035
regulation of cellular ketone metabolic processGO:0010565500.034
blastoderm segmentationGO:000735020.034
guanosine containing compound catabolic processGO:19010692390.033
gtp catabolic processGO:00061842370.033
intracellular protein transmembrane importGO:0044743230.033
neurotransmitter secretionGO:000726940.033
cell projection organizationGO:00300302520.033
protein foldingGO:0006457380.033
anatomical structure formation involved in morphogenesisGO:00486462840.033
proteasomal protein catabolic processGO:00104981760.033
Human
single organism cellular localizationGO:19025803320.032
cellular amine metabolic processGO:0044106410.032
regenerationGO:003109940.032
establishment of protein localization to organelleGO:00725941720.031
protein catabolic processGO:00301633250.030
Human
chromatin modificationGO:00165682980.030
small gtpase mediated signal transductionGO:0007264780.030
protein ubiquitinationGO:00165673140.030
Human
segmentationGO:003528240.030
muscle structure developmentGO:0061061980.030
Zebrafish
histone modificationGO:00165702510.029
positive regulation of meiotic cell cycleGO:005144620.029
extrinsic apoptotic signaling pathwayGO:00971911190.029
protein localization to endoplasmic reticulumGO:0070972190.029
single organism reproductive processGO:0044702980.029
Mouse
mapk cascadeGO:00001652880.028
mitochondrion organizationGO:00070051560.028
immune responseGO:00069553070.028
amine metabolic processGO:0009308440.028
organophosphate catabolic processGO:00464344300.028
regulation of anatomical structure morphogenesisGO:00226032860.027
microtubule based processGO:00070172100.027
symbiosis encompassing mutualism through parasitismGO:00444031560.026
regulation of protein kinase activityGO:00458592890.026
negative regulation of catalytic activityGO:00430863350.026
cellular amino acid metabolic processGO:00065201160.026
chaperone mediated protein foldingGO:0061077130.026
chaperone mediated protein folding requiring cofactorGO:005108510.025
mitochondrial membrane organizationGO:0007006400.025
nucleocytoplasmic transportGO:00069131760.025
glycosyl compound catabolic processGO:19016584130.025
jnk cascadeGO:0007254800.025
organelle assemblyGO:00709251760.025
sleepGO:003043120.025
regulation of gtpase activityGO:00430871800.025
regulation of cellular amino acid metabolic processGO:000652160.024
regulation of protein catabolic processGO:00421761550.024
Human
cellular response to misfolded proteinGO:007121820.024
regulation of homeostatic processGO:00328441210.024
regulation of cell migrationGO:00303342890.024
anterior posterior axis specificationGO:000994820.024
regulation of secretion by cellGO:19035301770.024
protein oligomerizationGO:00512591730.024
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.023
protein polymerizationGO:0051258710.023
cellular ketone metabolic processGO:0042180800.023
positive regulation of cellular component organizationGO:00511303760.023
positive regulation of protein catabolic processGO:0045732750.023
Human
response to unfolded proteinGO:0006986240.023
positive regulation of nucleoside metabolic processGO:00459791860.023
mitotic cell cycle processGO:19030472860.023
embryonic placenta developmentGO:000189210.023
Mouse
cell adhesionGO:00071553250.023
Mouse
positive regulation of proteolysisGO:00458621420.023
Human
negative regulation of protein phosphorylationGO:00019331400.023
response to lithium ionGO:001022620.023
regulation of mapk cascadeGO:00434082620.023
cellular response to cytokine stimulusGO:00713451810.023
cotranslational protein targeting to membraneGO:000661320.023
reproductive processGO:00224141060.023
Mouse
cellular response to tumor necrosis factorGO:0071356630.022
detection of stimulusGO:0051606850.022
lipid metabolic processGO:00066293810.022
actin filament organizationGO:00070151280.022
spinal cord developmentGO:002151040.022
system processGO:00030083490.022
purine ribonucleoside catabolic processGO:00461303980.022
positive regulation of developmental processGO:00510943140.022
positive regulation of transportGO:00510503360.022
tissue regenerationGO:004224630.021
protein targetingGO:00066051870.021
nuclear transportGO:00511691790.021
regulation of cellular component movementGO:00512703340.021
regulation of symbiosis encompassing mutualism through parasitismGO:00439031090.021
positive regulation of gtpase activityGO:00435471660.021
regulation of cell differentiationGO:00455953930.021
meiosis iGO:000712740.021
nucleoside monophosphate metabolic processGO:00091231910.021
positive regulation of protein transportGO:00512221350.021
microtubule cytoskeleton organizationGO:00002261760.021
protein maturationGO:00516042330.021
positive regulation of organelle organizationGO:00106381950.021
regulation of secretionGO:00510461940.021
negative regulation of cell growthGO:0030308830.021
Human
protein targeting to nucleusGO:00447441040.021
cation transportGO:00068123310.020
protein processingGO:00164852260.020
nucleus localizationGO:005164710.020
regulation of cellular amine metabolic processGO:0033238110.020
growthGO:00400072020.020
Human
spermatid developmentGO:000728640.020
protein import into nucleusGO:00066061040.020
response to cytokineGO:00340972320.020
myosin filament organizationGO:003103320.020
biological adhesionGO:00226103310.020
Mouse
regulation of locomotionGO:00400123290.020
translationGO:00064121320.020
ras protein signal transductionGO:0007265730.019
purine nucleoside triphosphate catabolic processGO:00091463920.019
regulation of intracellular transportGO:00323861950.019
positive regulation of secretionGO:00510471160.019
regulation of gene expression epigeneticGO:0040029730.019
regulation of meiotic cell cycleGO:005144540.019
cell projection morphogenesisGO:00488581290.019
rna splicingGO:00083801310.019
retrograde transport endosome to golgiGO:0042147450.019
cation transmembrane transportGO:00986552380.019
protein transmembrane transportGO:0071806250.019
negative regulation of transportGO:00510511760.019
regulation of ion transportGO:00432691890.018
regulation of cellular response to stressGO:00801352440.018
positive regulation of immune system processGO:00026842830.018
regulation of proteasomal protein catabolic processGO:0061136870.018
Human
regulation of protein complex assemblyGO:00432541470.018
mitotic cell cycle phase transitionGO:00447721620.018
positive regulation of purine nucleotide catabolic processGO:00331231850.018
negative regulation of intracellular signal transductionGO:19025321830.018
signal transduction by phosphorylationGO:00230142970.018
negative regulation of apoptotic signaling pathwayGO:2001234970.018
agingGO:0007568660.018
divalent inorganic cation transportGO:00725111580.018
macromolecule methylationGO:0043414970.018
regulation of cytokine productionGO:00018172320.018
negative regulation of inclusion body assemblyGO:009008490.018
maintenance of locationGO:00512351120.018
purine nucleotide catabolic processGO:00061954050.018
protein localization to organelleGO:00333652800.018
Mouse
circadian behaviorGO:004851220.018
striated muscle cell apoptotic processGO:001065830.017
neurogenesisGO:00220081690.017
engulfment of apoptotic cellGO:004365220.017
regulation of circadian sleep wake cycleGO:004274920.017
negative regulation of developmental processGO:00510932470.017
rab protein signal transductionGO:003248240.017
positive regulation of cellular component biogenesisGO:00440891580.017
regulation of protein maturationGO:19033171500.017
response to inorganic substanceGO:00100351270.017
positive regulation of nucleotide catabolic processGO:00308131850.017
cellular homeostasisGO:00197251960.017
response to organic cyclic compoundGO:00140702040.017
regulation of cytoskeleton organizationGO:00514931770.017
striated muscle myosin thick filament assemblyGO:007168820.017
regulation of gtp catabolic processGO:00331241800.016
neurological system processGO:00508771630.016
response to external biotic stimulusGO:00432072610.016
protein deacetylationGO:0006476380.016
purine ribonucleoside monophosphate metabolic processGO:00091671860.016
sensory perceptionGO:00076001030.016
motor neuron axon guidanceGO:000804520.016
positive regulation of gtp catabolic processGO:00331261660.016
chaperone mediated protein complex assemblyGO:005113190.016
protein deacylationGO:0035601390.016
reactive oxygen species metabolic processGO:0072593750.016
oocyte differentiationGO:000999420.016
protein importGO:00170381300.016
regulation of small gtpase mediated signal transductionGO:00510561560.016
positive regulation of cell cycleGO:00457871400.016
response to nitrogen compoundGO:19016981840.016
anterior posterior axis specification embryoGO:000859520.016
response to woundingGO:00096111680.016
regulation of cellular protein catabolic processGO:1903362960.016
Human
negative regulation of striated muscle cell apoptotic processGO:001066420.016
regulation of neurotransmitter secretionGO:004692830.016
response to virusGO:00096151260.016
regulation of stress activated protein kinase signaling cascadeGO:0070302850.016
circulatory system developmentGO:00723592620.016
protein import into mitochondrial matrixGO:003015010.016
regulation of response to external stimulusGO:00321012220.015
purine ribonucleoside monophosphate catabolic processGO:00091691580.015
spermatid differentiationGO:004851540.015
regulation of bindingGO:00510981110.015
sperm motilityGO:003031760.015
carbohydrate derivative biosynthetic processGO:19011372070.015
response to other organismGO:00517072610.015
single organism carbohydrate metabolic processGO:00447231930.015
calcium ion transportGO:00068161470.015
somitogenesisGO:000175620.015
regulation of immune responseGO:00507762010.015
plasma membrane organizationGO:00070091150.015
positive regulation of cellular amine metabolic processGO:003324070.015
taxisGO:00423301570.015
inorganic ion transmembrane transportGO:00986602310.015
substantia nigra developmentGO:0021762450.015
midbrain developmentGO:0030901450.015
response to tumor necrosis factorGO:0034612760.015
chemotaxisGO:00069351570.015
methylationGO:00322591060.015
maintenance of location in cellGO:0051651620.015
regulation of cell growthGO:00015581350.015
Human
regulation of protein stabilityGO:0031647870.015
myosin filament assemblyGO:003103420.015
immune effector processGO:00022521590.015
golgi vesicle transportGO:0048193800.015
regulation of cytoplasmic transportGO:19036491490.015
dephosphorylationGO:00163112090.015
limbic system developmentGO:002176130.015
cell cycle arrestGO:0007050710.015
response to light stimulusGO:0009416870.014
neuron differentiationGO:00301821380.014
positive regulation of protein complex assemblyGO:0031334860.014
cell morphogenesisGO:00009022960.014
positive regulation of cell differentiationGO:00455972110.014
copulationGO:000762010.014
spindle elongationGO:005123140.014
negative regulation of jnk cascadeGO:0046329160.014
regulation of map kinase activityGO:00434051080.014
response to axon injuryGO:004867810.014
regulation of cell motilityGO:20001452990.014
negative regulation of organelle organizationGO:00106391260.014
regulation of neural precursor cell proliferationGO:200017740.014
cell activationGO:00017752130.014
neuron projection developmentGO:00311751060.014
negative regulation of proteolysisGO:00458611320.014
rna processingGO:00063962550.014
multicellular organismal response to stressGO:003355510.014
negative regulation of mapk cascadeGO:0043409560.014
cell cycle phase transitionGO:00447701730.014
carbohydrate metabolic processGO:00059752070.014
blood vessel morphogenesisGO:00485141620.014
regulation of protein bindingGO:0043393660.014
divalent metal ion transportGO:00708381520.014
covalent chromatin modificationGO:00165692540.014
actomyosin structure organizationGO:0031032590.014
protein localization to mitochondrionGO:0070585250.014
regulation of cell cycle phase transitionGO:19019871260.014
regulation of protein polymerizationGO:0032271630.013
regulation of ras protein signal transductionGO:00465781550.013
positive regulation of ras gtpase activityGO:00323201170.013
morphogenesis of embryonic epitheliumGO:001633140.013
cardiovascular system developmentGO:00723582620.013
protein stabilizationGO:0050821640.013
circadian sleep wake cycle sleepGO:005080220.013
negative regulation of protein kinase activityGO:0006469980.013
vesicle mediated transportGO:00161923710.013
regulation of multi organism processGO:00439001570.013
interspecies interaction between organismsGO:00444191560.013
organelle fissionGO:00482851490.013
muscle cell differentiationGO:0042692630.013
protein localization to nucleusGO:00345041360.013
Mouse
regulation of nucleocytoplasmic transportGO:0046822980.013
regulation of defense responseGO:00313471540.013
atp metabolic processGO:00460341760.013
negative regulation of protein transportGO:0051224750.013
rhythmic behaviorGO:000762220.013
wound healingGO:00420601150.013
rho protein signal transductionGO:0007266260.013
sensory perception of painGO:001923340.013
viral processGO:00160321460.013
innate immune responseGO:00450871780.012
ion transmembrane transportGO:00342203380.012
single organism nuclear importGO:19025931040.012
stress activated protein kinase signaling cascadeGO:0031098940.012
regulation of mitotic cell cycleGO:00073461890.012
response to radiationGO:00093141510.012
muscle system processGO:0003012810.012
apoptotic mitochondrial changesGO:0008637570.012
cell cell signalingGO:00072671550.012
negative regulation of multicellular organismal processGO:00512413170.012
positive regulation of intracellular protein transportGO:0090316760.012
cellular response to external stimulusGO:00714961110.012
actin mediated cell contractionGO:0070252120.012
positive regulation of cell migrationGO:00303351720.012
intrinsic apoptotic signaling pathwayGO:00971931270.012
cellular component disassemblyGO:0022411920.012
photoreceptor cell differentiationGO:004653020.012
positive regulation of synaptic transmissionGO:005080640.012
positive regulation of immune responseGO:00507781590.012
negative regulation of nf kappab transcription factor activityGO:0032088510.012
negative regulation of axon extensionGO:003051720.012
regulation of extrinsic apoptotic signaling pathwayGO:2001236850.012
positive regulation of protein ubiquitinationGO:0031398530.012
Human
positive regulation of secretion by cellGO:19035321080.012
regulation of sequence specific dna binding transcription factor activityGO:00510902110.012
lipid biosynthetic processGO:00086101770.012
response to organonitrogen compoundGO:00102431560.012
regulation of synaptic plasticityGO:004816730.012
head developmentGO:00603221080.012
regulation of proteolysisGO:00301622930.012
peptidyl lysine modificationGO:00182051440.012
myeloid cell differentiationGO:00300991170.012
response to oxidative stressGO:00069791210.011
metal ion transportGO:00300012720.011
stem cell divisionGO:001714520.011
positive regulation of phosphorylationGO:00423273940.011
positive regulation of cell cycle processGO:00900681060.011
anion transportGO:00068201610.011
endomembrane system organizationGO:00102561960.011
macromolecule deacylationGO:0098732410.011
regulation of cell adhesionGO:00301551660.011
response to oxygen containing compoundGO:19017003690.011
cell part morphogenesisGO:00329901370.011
negative regulation of protein maturationGO:19033181420.011
regulation of proteolysis involved in cellular protein catabolic processGO:1903050910.011
Human
embryo developmentGO:00097901230.011
Mouse
developmental growthGO:0048589480.011
cellular lipid metabolic processGO:00442553030.011
response to uvGO:0009411730.011
negative regulation of extrinsic apoptotic signaling pathwayGO:2001237520.011
blastocyst developmentGO:000182430.011
negative regulation of jun kinase activityGO:004350840.011
neuron developmentGO:00486661130.011
regulation of transmembrane transportGO:00347621390.011
canonical wnt signaling pathwayGO:00600701160.011
cellular response to dna damage stimulusGO:00069743790.011
regulation of viral processGO:00507921030.011
organelle inheritanceGO:004830820.011
associative learningGO:000830610.011
hematopoietic or lymphoid organ developmentGO:00485341860.011
blood vessel developmentGO:00015681720.011
organonitrogen compound biosynthetic processGO:19015662000.011
positive regulation of protein phosphorylationGO:00019343130.011
response to fungusGO:000962040.011
regulation of growthGO:00400081650.011
Human
atp catabolic processGO:00062001570.011
glycerophospholipid metabolic processGO:0006650840.010
regulation of reactive oxygen species biosynthetic processGO:190342630.010
negative regulation of camp mediated signalingGO:004395140.010
muscle cell developmentGO:0055001290.010
neuron apoptotic processGO:0051402390.010
synaptic vesicle endocytosisGO:004848820.010
regulation of intracellular protein transportGO:00331571230.010
cell morphogenesis involved in differentiationGO:00009041440.010
cell growthGO:00160491600.010
Human
negative regulation of sequence specific dna binding transcription factor activityGO:0043433890.010
negative regulation of catabolic processGO:00098951040.010
negative regulation of neuron deathGO:1901215320.010
positive regulation of cellular component movementGO:00512721810.010
protein k48 linked ubiquitinationGO:0070936380.010
regulation of mitotic cell cycle phase transitionGO:19019901180.010
nuclear divisionGO:00002801280.010

DNAJB6 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
musculoskeletal system diseaseDOID:172230.110
muscle tissue diseaseDOID:661130.039
muscular diseaseDOID:00800001140.039
heart diseaseDOID:114680.031
cardiovascular system diseaseDOID:12871060.031
disease of cellular proliferationDOID:145661740.021
connective tissue diseaseDOID:651090.017
disease of mental healthDOID:150700.017
cancerDOID:1621670.017
immune system diseaseDOID:29141550.016
nervous system diseaseDOID:8634310.014
central nervous system diseaseDOID:3311860.014
organ system cancerDOID:00506861640.014
sensory system diseaseDOID:00501552030.012
integumentary system diseaseDOID:16430.010
skin diseaseDOID:37330.010
disease of metabolismDOID:00146672950.010
myopathyDOID:4231040.009
muscular dystrophyDOID:9884510.004
limb girdle muscular dystrophyDOID:11724250.003