Homo sapiens

0 known processes

HELZ

helicase with zinc finger

(Aliases: KIAA0054,DKFZp586G1924,HUMORF5,DRHC,MGC163454,DHRC)

HELZ biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
chromatin modificationGO:00165682980.454
chromatin organizationGO:00063253510.288
covalent chromatin modificationGO:00165692540.231
nucleoside triphosphate catabolic processGO:00091433940.162
nucleoside triphosphate metabolic processGO:00091414220.151
purine ribonucleoside triphosphate catabolic processGO:00092073910.147
cardiovascular system developmentGO:00723582620.135
histone modificationGO:00165702510.134
purine nucleotide catabolic processGO:00061954050.120
purine ribonucleoside metabolic processGO:00461284370.118
nucleoside catabolic processGO:00091644080.110
macromolecule methylationGO:0043414970.107
cell developmentGO:00484683280.105
glycosyl compound catabolic processGO:19016584130.105
nervous system developmentGO:00073992930.095
nucleotide catabolic processGO:00091664080.093
purine nucleoside triphosphate metabolic processGO:00091444120.093
regulation of cell differentiationGO:00455953930.092
purine nucleoside catabolic processGO:00061523980.092
determination of adult lifespanGO:000834020.091
regulation of cellular amino acid metabolic processGO:000652160.088
purine ribonucleoside triphosphate metabolic processGO:00092054110.086
nucleoside phosphate catabolic processGO:19012924120.085
purine containing compound catabolic processGO:00725234110.085
ribonucleoside triphosphate metabolic processGO:00091994120.085
histone demethylationGO:0016577150.075
ribonucleotide catabolic processGO:00092614050.074
histone methylationGO:0016571600.072
purine ribonucleotide catabolic processGO:00091544040.071
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.070
cellular component morphogenesisGO:00329893140.070
nucleoside monophosphate catabolic processGO:00091251590.069
multicellular organismal agingGO:001025930.067
cellular amine metabolic processGO:0044106410.067
post embryonic developmentGO:000979120.067
purine ribonucleoside catabolic processGO:00461303980.067
circulatory system developmentGO:00723592620.066
cellular amino acid metabolic processGO:00065201160.065
generation of neuronsGO:00486991520.064
regulation of cellular amine metabolic processGO:0033238110.063
ribonucleoside catabolic processGO:00424544060.063
response to oxygen containing compoundGO:19017003690.061
amine metabolic processGO:0009308440.060
cell morphogenesisGO:00009022960.060
embryonic placenta developmentGO:000189210.060
positive regulation of cellular amine metabolic processGO:003324070.058
intracellular receptor signaling pathwayGO:00305221040.057
ribonucleoside triphosphate catabolic processGO:00092033910.057
neuron projection developmentGO:00311751060.057
rab protein signal transductionGO:003248240.057
segmentationGO:003528240.056
purine nucleoside triphosphate catabolic processGO:00091463920.056
cellular ketone metabolic processGO:0042180800.056
regulation of anatomical structure morphogenesisGO:00226032860.055
positive regulation of cellular catabolic processGO:00313312840.055
biological adhesionGO:00226103310.054
methylationGO:00322591060.053
positive regulation of cellular amino acid metabolic processGO:004576430.053
oogenesisGO:004847720.052
regulation of cellular ketone metabolic processGO:0010565500.051
response to biotic stimulusGO:00096072760.050
cell projection organizationGO:00300302520.050
negative regulation of protein metabolic processGO:00512483910.050
cellular response to organic cyclic compoundGO:00714071270.050
small gtpase mediated signal transductionGO:0007264780.050
immune responseGO:00069553070.048
regulation of cell cycleGO:00517263930.048
purine nucleoside monophosphate metabolic processGO:00091261860.047
morphogenesis of embryonic epitheliumGO:001633140.047
cell projection morphogenesisGO:00488581290.046
locomotory behaviorGO:000762610.045
vesicle mediated transportGO:00161923710.044
ras protein signal transductionGO:0007265730.043
dephosphorylationGO:00163112090.043
ribonucleoside monophosphate metabolic processGO:00091611870.042
negative regulation of cellular protein metabolic processGO:00322693530.042
neuromuscular junction developmentGO:000752830.042
cytoplasmic transportGO:00164823790.041
demethylationGO:0070988370.041
regulation of nucleotide metabolic processGO:00061402690.041
regulation of cell developmentGO:00602841610.041
cell morphogenesis involved in differentiationGO:00009041440.040
cellular response to dna damage stimulusGO:00069743790.040
ribonucleoside monophosphate catabolic processGO:00091581580.040
regulation of purine nucleotide metabolic processGO:19005422640.040
memoryGO:000761330.040
positive regulation of developmental processGO:00510943140.039
histone lysine methylationGO:0034968500.039
cell cycle phase transitionGO:00447701730.038
cellular response to oxygen containing compoundGO:19017012760.038
cell adhesionGO:00071553250.038
growthGO:00400072020.037
histone acetylationGO:0016573930.037
negative regulation of catalytic activityGO:00430863350.035
anatomical structure formation involved in morphogenesisGO:00486462840.035
central nervous system developmentGO:00074171230.035
cellular response to endogenous stimulusGO:00714953360.035
hindbrain developmentGO:003090230.034
response to other organismGO:00517072610.034
system processGO:00030083490.034
positive regulation of cellular component organizationGO:00511303760.033
negative regulation of developmental processGO:00510932470.033
guanosine containing compound catabolic processGO:19010692390.033
purine ribonucleoside monophosphate catabolic processGO:00091691580.033
heart developmentGO:0007507950.032
positive regulation of nucleotide metabolic processGO:00459812300.032
atp metabolic processGO:00460341760.032
innate immune responseGO:00450871780.032
spermatid differentiationGO:004851540.032
response to external biotic stimulusGO:00432072610.031
guanosine containing compound metabolic processGO:19010682440.031
positive regulation of purine nucleotide metabolic processGO:19005442270.031
defense responseGO:00069523150.031
peptidyl lysine modificationGO:00182051440.030
positive regulation of catabolic processGO:00098963100.030
regulation of immune responseGO:00507762010.029
positive regulation of gtpase activityGO:00435471660.029
negative regulation of cell differentiationGO:00455961710.029
cellular response to growth factor stimulusGO:00713631970.029
female gamete generationGO:000729220.029
regulation of cellular component biogenesisGO:00440872810.028
metencephalon developmentGO:002203720.028
cerebellum developmentGO:002154920.028
ubiquitin dependent protein catabolic processGO:00065112060.028
epithelium developmentGO:00604292270.028
protein maturationGO:00516042330.028
gtp metabolic processGO:00460392390.028
proteolysis involved in cellular protein catabolic processGO:00516032440.028
enzyme linked receptor protein signaling pathwayGO:00071673030.028
brain developmentGO:0007420970.027
regulation of gtpase activityGO:00430871800.027
protein ubiquitinationGO:00165673140.027
tube closureGO:006060630.027
purine ribonucleoside monophosphate metabolic processGO:00091671860.027
gtp catabolic processGO:00061842370.027
chemotaxisGO:00069351570.026
negative regulation of phosphorus metabolic processGO:00105632670.026
neurogenesisGO:00220081690.026
embryonic epithelial tube formationGO:000183840.026
cellular response to lipidGO:00713961270.026
cell part morphogenesisGO:00329901370.026
regulation of transferase activityGO:00513383550.026
wnt signaling pathwayGO:00160551560.026
protein modification by small protein removalGO:0070646920.026
regulation of nucleoside metabolic processGO:00091182090.026
immune system developmentGO:00025201950.026
nucleosome organizationGO:0034728660.026
negative regulation of hydrolase activityGO:00513461820.025
mitotic cell cycleGO:00002783260.025
negative regulation of phosphate metabolic processGO:00459362670.025
atp catabolic processGO:00062001570.025
organophosphate catabolic processGO:00464344300.024
positive regulation of protein phosphorylationGO:00019343130.024
blood vessel developmentGO:00015681720.024
positive regulation of rab gtpase activityGO:0032851390.024
positive regulation of nucleotide catabolic processGO:00308131850.024
negative regulation of cellular component organizationGO:00511292350.024
hemopoiesisGO:00300971800.024
protein catabolic processGO:00301633250.024
hematopoietic or lymphoid organ developmentGO:00485341860.023
protein alkylationGO:0008213740.023
protein processingGO:00164852260.023
rhythmic behaviorGO:000762220.023
regulation of protein maturationGO:19033171500.023
response to growth factorGO:00708482050.023
negative regulation of protein modification processGO:00314002000.023
forelimb morphogenesisGO:003513640.023
nucleoside monophosphate metabolic processGO:00091231910.023
cell growthGO:00160491600.023
head developmentGO:00603221080.023
positive regulation of phosphorylationGO:00423273940.022
negative regulation of intracellular signal transductionGO:19025321830.022
negative regulation of protein processingGO:00109551420.022
stem cell developmentGO:0048864690.022
regulation of protein kinase activityGO:00458592890.022
regulation of sequence specific dna binding transcription factor activityGO:00510902110.022
regulation of jak stat cascadeGO:0046425440.022
protein methylationGO:0006479740.021
cellular protein catabolic processGO:00442572610.021
secretionGO:00469032540.021
mitotic cell cycle processGO:19030472860.021
regulation of cell cycle processGO:00105642660.021
jak stat cascadeGO:0007259460.021
positive regulation of transferase activityGO:00513472270.021
neuron developmentGO:00486661130.020
intracellular steroid hormone receptor signaling pathwayGO:0030518610.020
peptidyl lysine acetylationGO:00183941010.020
cellular macromolecule catabolic processGO:00442653800.020
neuron differentiationGO:00301821380.020
neuroblast proliferationGO:000740540.020
regulation of cell morphogenesisGO:00226041530.020
membrane organizationGO:00610242920.020
negative regulation of multicellular organismal processGO:00512413170.020
protein localization to organelleGO:00333652800.020
regulation of small gtpase mediated signal transductionGO:00510561560.019
response to abiotic stimulusGO:00096283360.019
single organism membrane organizationGO:00448022680.019
positive regulation of hydrolase activityGO:00513453310.019
neurological system processGO:00508771630.019
protein acetylationGO:00064731160.019
regulation of protein localizationGO:00328802960.019
negative regulation of organelle organizationGO:00106391260.019
protein modification by small protein conjugationGO:00324463420.019
regulation of response to external stimulusGO:00321012220.019
taxisGO:00423301570.019
protein targetingGO:00066051870.019
regulation of cellular response to stressGO:00801352440.019
response to lipidGO:00339932060.019
regulation of ras gtpase activityGO:00323181280.019
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.019
embryo developmentGO:00097901230.019
regulation of gtp catabolic processGO:00331241800.018
positive regulation of cell differentiationGO:00455972110.018
lipid metabolic processGO:00066293810.018
single organism cellular localizationGO:19025803320.018
protein deubiquitinationGO:0016579790.018
interspecies interaction between organismsGO:00444191560.018
neural tube formationGO:000184130.018
reproductive processGO:00224141060.018
histone h3 acetylationGO:0043966450.018
rho protein signal transductionGO:0007266260.018
negative regulation of phosphorylationGO:00423261740.018
negative regulation of immune system processGO:00026831360.018
cellular macromolecular complex assemblyGO:00346223240.018
positive regulation of transportGO:00510503360.018
negative regulation of proteolysisGO:00458611320.018
regulation of protein processingGO:00706131500.018
regulation of kinase activityGO:00435493140.018
positive regulation of immune system processGO:00026842830.018
regulation of ras protein signal transductionGO:00465781550.017
cellular response to nitrogen compoundGO:19016991440.017
limbic system developmentGO:002176130.017
circadian behaviorGO:004851220.017
vasculature developmentGO:00019441810.017
agingGO:0007568660.017
regulation of nucleotide catabolic processGO:00308112050.017
long term memoryGO:000761620.017
immune effector processGO:00022521590.017
regulation of cytoskeleton organizationGO:00514931770.017
regulation of cell morphogenesis involved in differentiationGO:0010769830.017
oxidation reduction processGO:00551143960.017
positive regulation of purine nucleotide catabolic processGO:00331231850.017
primary neural tube formationGO:001402030.017
negative regulation of cellular amine metabolic processGO:003323930.017
modification dependent macromolecule catabolic processGO:00436322120.017
apoptotic signaling pathwayGO:00971902680.017
cellular lipid metabolic processGO:00442553030.017
regulation of defense responseGO:00313471540.017
mapk cascadeGO:00001652880.017
negative regulation of cell cycleGO:00457861930.016
regulation of innate immune responseGO:0045088970.016
positive regulation of cell proliferationGO:00082843010.016
regulation of purine nucleotide catabolic processGO:00331212050.016
positive regulation of nucleoside metabolic processGO:00459791860.016
single organism reproductive processGO:0044702980.016
positive regulation of wnt signaling pathwayGO:0030177540.016
internal protein amino acid acetylationGO:00064751010.016
regulation of wnt signaling pathwayGO:00301111230.016
cellular protein complex assemblyGO:00436231880.016
negative regulation of programmed cell deathGO:00430693210.016
regulation of cell cycle phase transitionGO:19019871260.016
endomembrane system organizationGO:00102561960.016
positive regulation of organelle organizationGO:00106381950.016
cell cell signalingGO:00072671550.016
engulfment of apoptotic cellGO:004365220.015
regulation of protein stabilityGO:0031647870.015
regulation of growthGO:00400081650.015
negative regulation of protein maturationGO:19033181420.015
regulation of cell projection organizationGO:00313441070.015
negative regulation of immune responseGO:0050777400.015
positive regulation of cellular component biogenesisGO:00440891580.015
maintenance of locationGO:00512351120.015
negative regulation of chromosome organizationGO:2001251480.015
actin filament based processGO:00300292240.015
regulation of multi organism processGO:00439001570.015
negative regulation of cell cycle phase transitionGO:1901988890.015
posttranscriptional regulation of gene expressionGO:00106082130.015
regulation of rab gtpase activityGO:0032313390.015
neuron projection morphogenesisGO:0048812500.015
negative regulation of cellular amino acid metabolic processGO:004576320.015
stem cell differentiationGO:0048863930.015
dna damage checkpointGO:0000077680.015
regulation of cell growthGO:00015581350.015
chordate embryonic developmentGO:0043009340.015
regulation of mitotic cell cycle phase transitionGO:19019901180.015
endocytosisGO:00068971590.015
cell divisionGO:00513011680.014
neural tube closureGO:000184330.014
compound eye developmentGO:004874910.014
establishment of protein localization to organelleGO:00725941720.014
humoral immune responseGO:0006959490.014
autophagyGO:0006914880.014
muscle structure developmentGO:0061061980.014
signal transduction by phosphorylationGO:00230142970.014
negative regulation of cell deathGO:00605483450.014
regulation of proteolysisGO:00301622930.014
defense response to other organismGO:00985421290.014
tube developmentGO:00352951250.014
regulation of chromatin modificationGO:1903308510.014
carbohydrate derivative biosynthetic processGO:19011372070.014
mitotic cell cycle checkpointGO:0007093680.014
negative regulation of jak stat cascadeGO:004642640.014
transmembrane transportGO:00550853990.014
negative regulation of mitotic cell cycle phase transitionGO:1901991850.014
regulation of cell divisionGO:00513021160.013
regulation of cell adhesionGO:00301551660.013
blood vessel morphogenesisGO:00485141620.013
motor neuron axon guidanceGO:000804520.013
organ morphogenesisGO:00098871470.013
canonical wnt signaling pathwayGO:00600701160.013
internal peptidyl lysine acetylationGO:0018393970.013
nitrogen compound transportGO:00717051910.013
regulation of stem cell differentiationGO:2000736560.013
response to nitrogen compoundGO:19016981840.013
response to organic cyclic compoundGO:00140702040.013
negative regulation of mitotic cell cycleGO:00459301020.013
glycerolipid metabolic processGO:00464861070.013
modification dependent protein catabolic processGO:00199412090.013
cellular response to organonitrogen compoundGO:00714171240.013
organelle assemblyGO:00709251760.013
bmp signaling pathwayGO:0030509490.013
carbohydrate metabolic processGO:00059752070.012
epithelial cell proliferationGO:00506731280.012
cellular carbohydrate metabolic processGO:0044262840.012
oocyte differentiationGO:000999420.012
symbiosis encompassing mutualism through parasitismGO:00444031560.012
myeloid cell differentiationGO:00300991170.012
tissue morphogenesisGO:0048729960.012
blastoderm segmentationGO:000735020.012
secretion by cellGO:00329402260.012
pattern specification processGO:0007389430.012
negative regulation of synaptic transmissionGO:005080520.012
negative regulation of cell cycle processGO:00109481210.012
negative regulation of chromatin silencingGO:003193640.012
hippocampus developmentGO:002176610.012
organonitrogen compound biosynthetic processGO:19015662000.012
embryonic eye morphogenesisGO:004804820.012
response to bacteriumGO:00096171440.012
protein localization to membraneGO:00726571600.012
cell substrate adhesionGO:00315891320.012
protein demethylationGO:0006482170.012
response to hypoxiaGO:0001666960.012
reactive oxygen species biosynthetic processGO:190340940.012
positive regulation of protein kinase activityGO:00458601900.012
protein dna complex subunit organizationGO:0071824800.012
leukocyte differentiationGO:0002521980.012
glial cell migrationGO:000834740.012
protein polyubiquitinationGO:00002091100.012
chromatin remodelingGO:0006338550.012
positive regulation of ras gtpase activityGO:00323201170.012
cell activationGO:00017752130.012
inner ear morphogenesisGO:004247240.012
response to axon injuryGO:004867810.012
glycerophospholipid metabolic processGO:0006650840.012
embryonic organ developmentGO:0048568360.012
somitogenesisGO:000175620.012
somatic stem cell maintenanceGO:003501940.012
plasma membrane organizationGO:00070091150.012
negative regulation of catabolic processGO:00098951040.012
protein acylationGO:00435431380.011
nerve developmentGO:002167540.011
negative regulation of cell proliferationGO:00082852280.011
protein dealkylationGO:0008214170.011
regulation of hormone levelsGO:00108171250.011
peptidyl lysine methylationGO:0018022370.011
intracellular protein transportGO:00068862700.011
regulation of nervous system developmentGO:0051960880.011
chromosome segregationGO:00070591140.011
actin cytoskeleton organizationGO:00300362070.011
blood vessel maturationGO:000195510.011
male meiosisGO:000714010.011
mitotic nuclear divisionGO:00070671190.011
regulation of meiosisGO:004002030.011
endoderm developmentGO:0007492330.011
peripheral nervous system developmentGO:000742220.011
myosin filament assemblyGO:003103420.011
regulation of apoptotic signaling pathwayGO:20012331750.011
g2 dna damage checkpointGO:0031572260.011
response to organonitrogen compoundGO:00102431560.011
multi organism cellular processGO:00447641560.011
regulation of dephosphorylationGO:0035303960.011
cell morphogenesis involved in neuron differentiationGO:0048667440.011
response to oxygen levelsGO:00704821000.011
response to sterolGO:0036314140.011
regulation of symbiosis encompassing mutualism through parasitismGO:00439031090.011
dna integrity checkpointGO:0031570710.011
nuclear divisionGO:00002801280.011
adult locomotory behaviorGO:000834410.011
phospholipid metabolic processGO:0006644990.011
organelle fissionGO:00482851490.011
cellular component disassemblyGO:0022411920.011
regulation of cellular component movementGO:00512703340.011
ribonucleoprotein complex biogenesisGO:00226131160.011
positive regulation of insulin like growth factor receptor signaling pathwayGO:004356840.011
mitotic spindle elongationGO:000002240.011
dna repairGO:00062811980.011
lymphocyte activationGO:00466491330.011
regulation of endopeptidase activityGO:00525481700.010
ameboidal type cell migrationGO:00016671350.010
regulation of cytokine productionGO:00018172320.010
response to woundingGO:00096111680.010
cerebellar cortex developmentGO:002169510.010
epidermis morphogenesisGO:004873030.010
response to inorganic substanceGO:00100351270.010
establishment of nucleus localizationGO:004002310.010
embryonic forelimb morphogenesisGO:003511540.010
inorganic ion transmembrane transportGO:00986602310.010
positive regulation of gtp catabolic processGO:00331261660.010
response to hormoneGO:00097251750.010
regulation of vesicle mediated transportGO:00606271300.010

HELZ disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:145661740.018
organ system cancerDOID:00506861640.018
cancerDOID:1621670.018
central nervous system diseaseDOID:3311860.017
nervous system diseaseDOID:8634310.017
neurodegenerative diseaseDOID:12891020.015
immune system diseaseDOID:29141550.011