Homo sapiens

63 known processes

MSH3

mutS homolog 3 (E. coli)

(Aliases: DUP,MGC163308,MRP1,MGC163306)

MSH3 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
nucleotide excision repairGO:0006289310.779
dna repairGO:00062811980.714
mismatch repairGO:0006298150.707
cellular response to dna damage stimulusGO:00069743790.691
double strand break repairGO:00063021010.560
isotype switchingGO:004519030.503
dna recombinationGO:0006310770.407
sex determinationGO:000753030.394
Yeast
somatic recombination of immunoglobulin gene segmentsGO:001644740.342
Mouse
dna damage checkpointGO:0000077680.327
somatic recombination of immunoglobulin genes involved in immune responseGO:000220430.305
somatic diversification of immune receptors via somatic mutationGO:000256610.296
nucleic acid phosphodiester bond hydrolysisGO:00903051020.256
Yeast
telomere maintenanceGO:0000723320.239
purine nucleoside catabolic processGO:00061523980.199
Yeast
anatomical structure homeostasisGO:00602491000.199
purine ribonucleoside triphosphate catabolic processGO:00092073910.193
Yeast
positive regulation of hydrolase activityGO:00513453310.190
cellular macromolecule catabolic processGO:00442653800.189
Yeast
lymphocyte mediated immunityGO:0002449480.182
double strand break repair via homologous recombinationGO:0000724500.175
purine ribonucleoside catabolic processGO:00461303980.173
Yeast
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630500.165
meiosis iGO:000712740.157
Yeast
apoptotic signaling pathwayGO:00971902680.155
ribonucleotide catabolic processGO:00092614050.149
Yeast
purine nucleoside triphosphate catabolic processGO:00091463920.147
Yeast
purine nucleotide catabolic processGO:00061954050.146
Yeast
response to abiotic stimulusGO:00096283360.140
response to radiationGO:00093141510.139
purine nucleoside triphosphate metabolic processGO:00091444120.138
Yeast
immune responseGO:00069553070.138
somatic diversification of immunoglobulins involved in immune responseGO:000220830.137
dna double strand break processingGO:0000729100.133
glycosyl compound catabolic processGO:19016584130.132
Yeast
interstrand cross link repairGO:003629730.127
purine nucleoside monophosphate catabolic processGO:00091281580.122
Yeast
intrinsic apoptotic signaling pathwayGO:00971931270.121
nucleoside catabolic processGO:00091644080.120
Yeast
regulation of dna recombinationGO:0000018230.120
nucleoside phosphate catabolic processGO:19012924120.110
Yeast
negative regulation of cell cycleGO:00457861930.109
purine ribonucleotide catabolic processGO:00091544040.108
Yeast
cell developmentGO:00484683280.108
purine containing compound catabolic processGO:00725234110.107
Yeast
somatic hypermutation of immunoglobulin genesGO:001644610.106
nucleoside monophosphate metabolic processGO:00091231910.103
Yeast
dna replicationGO:00062601160.102
multicellular organismal agingGO:001025930.101
ribonucleoside monophosphate metabolic processGO:00091611870.097
Yeast
response to ionizing radiationGO:0010212650.096
determination of adult lifespanGO:000834020.094
dna integrity checkpointGO:0031570710.094
recombinational repairGO:0000725500.093
immune system developmentGO:00025201950.089
Mouse
nucleoside triphosphate catabolic processGO:00091433940.089
Yeast
negative regulation of mitotic cell cycleGO:00459301020.086
double strand break repair via single strand annealingGO:004500240.086
regulation of dna metabolic processGO:00510521530.085
regulation of cell cycleGO:00517263930.085
somatic diversification of immunoglobulinsGO:001644560.082
Mouse
regulation of meiotic cell cycleGO:005144540.080
b cell activationGO:0042113330.077
telomere maintenance via telomeraseGO:000700480.076
negative regulation of cell cycle phase transitionGO:1901988890.075
leukocyte mediated immunityGO:0002443590.075
nucleoside triphosphate metabolic processGO:00091414220.074
Yeast
leukocyte activationGO:00453211640.073
ribonucleoside triphosphate catabolic processGO:00092033910.073
Yeast
nucleotide catabolic processGO:00091664080.072
Yeast
purine ribonucleoside metabolic processGO:00461284370.071
Yeast
ribonucleoside catabolic processGO:00424544060.071
Yeast
adaptive immune responseGO:0002250490.069
intra s dna damage checkpointGO:003157340.068
rna processingGO:00063962550.068
regulation of cell cycle phase transitionGO:19019871260.068
meiotic chromosome segregationGO:004513240.067
purine ribonucleoside monophosphate catabolic processGO:00091691580.065
Yeast
response to uvGO:0009411730.064
dna catabolic processGO:0006308490.064
Yeast
immune effector processGO:00022521590.063
regulation of cell divisionGO:00513021160.062
atp metabolic processGO:00460341760.061
Yeast
midbrain developmentGO:0030901450.060
cell cycle checkpointGO:00000751170.056
ribonucleoside triphosphate metabolic processGO:00091994120.053
Yeast
negative regulation of cell cycle processGO:00109481210.052
negative regulation of programmed cell deathGO:00430693210.051
cellular protein complex assemblyGO:00436231880.050
regulation of meiosisGO:004002030.049
telomere maintenance via telomere lengtheningGO:001083390.048
maintenance of dna repeat elementsGO:004357040.048
ribonucleoside monophosphate catabolic processGO:00091581580.048
Yeast
purine ribonucleoside triphosphate metabolic processGO:00092054110.047
Yeast
nucleoside monophosphate catabolic processGO:00091251590.047
Yeast
cell morphogenesisGO:00009022960.047
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002460400.047
cellular response to abiotic stimulusGO:00712141170.047
purine nucleoside monophosphate metabolic processGO:00091261860.046
Yeast
regulation of cell cycle processGO:00105642660.046
negative regulation of cell deathGO:00605483450.044
compound eye developmentGO:004874910.044
somatic diversification of immune receptorsGO:000220080.043
Mouse
negative regulation of dna recombinationGO:004591060.042
atp catabolic processGO:00062001570.042
Yeast
nuclear divisionGO:00002801280.042
Yeast
cellular ketone metabolic processGO:0042180800.042
cellular amino acid metabolic processGO:00065201160.041
cell cycle arrestGO:0007050710.040
mitotic cell cycle phase transitionGO:00447721620.039
female gamete generationGO:000729220.038
purine ribonucleoside monophosphate metabolic processGO:00091671860.037
Yeast
ion homeostasisGO:00508012300.037
protein polyubiquitinationGO:00002091100.037
postreplication repairGO:0006301120.036
mitotic cell cycleGO:00002783260.036
cardiovascular system developmentGO:00723582620.036
positive regulation of helicase activityGO:005109660.036
organelle fissionGO:00482851490.036
Yeast
negative regulation of catalytic activityGO:00430863350.033
microtubule based processGO:00070172100.033
lymphocyte activationGO:00466491330.033
telomere maintenance via recombinationGO:000072240.033
protein processingGO:00164852260.033
regulation of anatomical structure morphogenesisGO:00226032860.032
cell activation involved in immune responseGO:0002263300.032
chromosome segregationGO:00070591140.031
cell divisionGO:00513011680.031
gene conversionGO:003582210.031
Yeast
lymphocyte activation involved in immune responseGO:0002285200.030
regenerationGO:003109940.030
leukocyte differentiationGO:0002521980.029
dna catabolic process exonucleolyticGO:0000738170.029
post embryonic developmentGO:000979120.029
oogenesisGO:004847720.029
amine metabolic processGO:0009308440.029
g2 dna damage checkpointGO:0031572260.029
protein ubiquitinationGO:00165673140.029
leukocyte activation involved in immune responseGO:0002366300.029
covalent chromatin modificationGO:00165692540.028
intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediatorGO:0042771230.028
hindbrain developmentGO:003090230.027
positive regulation of transportGO:00510503360.027
response to oxygen containing compoundGO:19017003690.027
regulation of establishment of protein localizationGO:00702012420.027
response to light stimulusGO:0009416870.027
regulation of cellular amino acid metabolic processGO:000652160.027
production of molecular mediator of immune responseGO:0002440370.027
Mouse
reciprocal meiotic recombinationGO:000713140.027
segmentationGO:003528240.027
mitotic dna damage checkpointGO:0044773280.026
regulation of helicase activityGO:005109580.026
blastoderm segmentationGO:000735020.026
positive regulation of protein phosphorylationGO:00019343130.026
signal transduction by phosphorylationGO:00230142970.026
cell projection organizationGO:00300302520.026
cellular response to external stimulusGO:00714961110.026
central nervous system developmentGO:00074171230.026
regulation of mitotic cell cycle phase transitionGO:19019901180.026
chemical homeostasisGO:00488783060.026
meiotic nuclear divisionGO:0007126100.026
Yeast
cellular homeostasisGO:00197251960.025
circulatory system developmentGO:00723592620.025
negative regulation of cellular component organizationGO:00511292350.025
signal transduction by p53 class mediatorGO:0072331720.024
negative regulation of mitotic cell cycle phase transitionGO:1901991850.024
organophosphate catabolic processGO:00464344300.024
Yeast
cytoplasmic transportGO:00164823790.024
regulation of mitotic cell cycleGO:00073461890.024
hemopoiesisGO:00300971800.024
blood vessel developmentGO:00015681720.024
meiotic gene conversionGO:000631110.023
proteolysis involved in cellular protein catabolic processGO:00516032440.023
negative regulation of meiotic cell cycleGO:005144720.023
positive regulation of cellular amino acid metabolic processGO:004576430.023
response to nitrogen compoundGO:19016981840.023
regulation of multi organism processGO:00439001570.023
cell activationGO:00017752130.023
ras protein signal transductionGO:0007265730.023
negative regulation of organelle organizationGO:00106391260.023
neural nucleus developmentGO:0048857470.023
angiogenesisGO:00015251470.022
regulation of cellular ketone metabolic processGO:0010565500.022
substantia nigra developmentGO:0021762450.022
positive regulation of cellular catabolic processGO:00313312840.022
response to organic cyclic compoundGO:00140702040.022
anatomical structure formation involved in morphogenesisGO:00486462840.022
metal ion homeostasisGO:00550651690.022
negative regulation of phosphorus metabolic processGO:00105632670.021
hematopoietic or lymphoid organ developmentGO:00485341860.021
immunoglobulin mediated immune responseGO:0016064100.021
regulation of cellular component biogenesisGO:00440872810.021
cell type specific apoptotic processGO:00972851250.021
protein maturationGO:00516042330.021
b cell mediated immunityGO:0019724100.020
immunoglobulin production involved in immunoglobulin mediated immune responseGO:000238150.020
innate immune responseGO:00450871780.020
mrna processingGO:00063971330.020
negative regulation of cell proliferationGO:00082852280.020
protein catabolic processGO:00301633250.020
regulation of transferase activityGO:00513383550.020
generation of precursor metabolites and energyGO:0006091680.020
tripartite regional subdivisionGO:000735120.020
protein autophosphorylationGO:00467771230.020
actin filament based processGO:00300292240.020
negative regulation of cellular amine metabolic processGO:003323930.020
development of primary male sexual characteristicsGO:0046546230.019
cellular response to endogenous stimulusGO:00714953360.019
meiotic cell cycleGO:0051321130.019
Yeast
positive regulation of programmed cell deathGO:00430682490.019
positive regulation of cellular amine metabolic processGO:003324070.019
calcium ion homeostasisGO:00550741220.019
telomere organizationGO:0032200330.019
response to lipidGO:00339932060.019
vasculature developmentGO:00019441810.019
regulation of cellular component movementGO:00512703340.019
protein modification by small protein conjugationGO:00324463420.019
regulation of protein transportGO:00512232130.018
regulation of kinase activityGO:00435493140.018
positive regulation of cell deathGO:00109422630.018
blastocyst developmentGO:000182430.018
cellular metal ion homeostasisGO:00068751460.018
dna catabolic process endonucleolyticGO:0000737370.018
Yeast
response to inorganic substanceGO:00100351270.018
regulation of vasculature developmentGO:1901342970.018
positive regulation of kinase activityGO:00336742040.018
regulation of cell differentiationGO:00455953930.018
negative regulation of cellular protein metabolic processGO:00322693530.018
cellular component morphogenesisGO:00329893140.018
positive regulation of protein transportGO:00512221350.018
anterior posterior axis specification embryoGO:000859520.017
regulation of locomotionGO:00400123290.017
regulation of dna replicationGO:0006275680.017
regulation of cell migrationGO:00303342890.017
response to biotic stimulusGO:00096072760.017
system processGO:00030083490.017
regulation of angiogenesisGO:0045765920.017
regulation of cell motilityGO:20001452990.017
cation homeostasisGO:00550801890.017
actin filament organizationGO:00070151280.017
tissue regenerationGO:004224630.017
nervous system developmentGO:00073992930.017
epithelial cell differentiationGO:00308551410.017
neuromuscular junction developmentGO:000752830.017
positive regulation of response to dna damage stimulusGO:2001022430.017
response to uv bGO:0010224100.017
male gonad developmentGO:0008584230.017
cellular ion homeostasisGO:00068731680.017
single organism cellular localizationGO:19025803320.017
dephosphorylationGO:00163112090.017
regulation of cellular amine metabolic processGO:0033238110.016
cell part morphogenesisGO:00329901370.016
regulation of protein localizationGO:00328802960.016
regulation of protein bindingGO:0043393660.016
intracellular mrna localizationGO:000829810.016
tube morphogenesisGO:0035239950.016
cellular amine metabolic processGO:0044106410.016
cellular macromolecular complex assemblyGO:00346223240.016
negative regulation of apoptotic processGO:00430663160.016
oocyte developmentGO:004859910.016
generation of neuronsGO:00486991520.016
positive regulation of phosphorylationGO:00423273940.016
cellular chemical homeostasisGO:00550821800.016
response to organonitrogen compoundGO:00102431560.016
positive regulation of cell differentiationGO:00455972110.016
cellular cation homeostasisGO:00300031630.016
non recombinational repairGO:0000726140.016
metencephalon developmentGO:002203720.016
response to caffeineGO:003100030.016
positive regulation of transferase activityGO:00513472270.015
regulation of cytokine productionGO:00018172320.015
positive regulation of cytokine productionGO:00018191670.015
somitogenesisGO:000175620.015
embryonic epithelial tube formationGO:000183840.015
reactive oxygen species metabolic processGO:0072593750.015
intracellular protein transportGO:00068862700.015
epithelium developmentGO:00604292270.015
negative regulation of blood vessel morphogenesisGO:2000181410.015
cellular protein catabolic processGO:00442572610.015
actin cytoskeleton organizationGO:00300362070.015
regulation of cell developmentGO:00602841610.015
cell projection assemblyGO:00300311260.015
positive regulation of cell proliferationGO:00082843010.015
negative regulation of developmental processGO:00510932470.015
multi organism cellular processGO:00447641560.015
negative regulation of dna metabolic processGO:0051053570.015
negative regulation of vasculature developmentGO:1901343430.015
organophosphate biosynthetic processGO:00904071630.015
positive regulation of developmental processGO:00510943140.015
response to woundingGO:00096111680.015
oocyte differentiationGO:000999420.015
brain developmentGO:0007420970.015
mrna metabolic processGO:00160711750.015
regulation of proteolysisGO:00301622930.014
regulation of sequence specific dna binding transcription factor activityGO:00510902110.014
translesion synthesisGO:001998580.014
regulation of symbiosis encompassing mutualism through parasitismGO:00439031090.014
anterior posterior axis specificationGO:000994820.014
cellular response to ionizing radiationGO:0071479320.014
small gtpase mediated signal transductionGO:0007264780.014
transmembrane transportGO:00550853990.014
regulation of immune responseGO:00507762010.014
defense responseGO:00069523150.014
neural tube closureGO:000184330.014
protein oligomerizationGO:00512591730.014
regulation of cell morphogenesisGO:00226041530.014
negative regulation of angiogenesisGO:0016525390.014
negative regulation of phosphate metabolic processGO:00459362670.014
nuclear transportGO:00511691790.014
neuron apoptotic processGO:0051402390.014
regulation of neuron deathGO:1901214560.014
morphogenesis of embryonic epitheliumGO:001633140.014
carbohydrate derivative biosynthetic processGO:19011372070.014
mapk cascadeGO:00001652880.014
inorganic ion transmembrane transportGO:00986602310.014
regulation of epithelial cell proliferationGO:00506781130.014
cell adhesionGO:00071553250.014
chromatin modificationGO:00165682980.014
retinal ganglion cell axon guidanceGO:003129020.014
negative regulation of cellular amino acid metabolic processGO:004576320.014
negative regulation of multicellular organismal processGO:00512413170.013
meiotic chromosome separationGO:005130730.013
spermatid developmentGO:000728640.013
reproductionGO:0000003630.013
Yeast
associative learningGO:000830610.013
regulation of protein kinase activityGO:00458592890.013
histone modificationGO:00165702510.013
epithelial cell proliferationGO:00506731280.013
regulation of cellular response to stressGO:00801352440.013
lipid metabolic processGO:00066293810.013
regulation of carbohydrate metabolic processGO:0006109540.013
response to hormoneGO:00097251750.013
membrane organizationGO:00610242920.013
male sex differentiationGO:0046661250.013
neuron deathGO:0070997650.013
memoryGO:000761330.013
chromatin organizationGO:00063253510.013
single organism membrane organizationGO:00448022680.013
immunoglobulin productionGO:0002377120.013
Mouse
base excision repairGO:0006284210.013
regulation of growthGO:00400081650.013
small molecule biosynthetic processGO:00442831570.013
cytokine productionGO:00018162470.013
primary neural tube formationGO:001402030.012
biological adhesionGO:00226103310.012
regulation of homeostatic processGO:00328441210.012
establishment of protein localization to organelleGO:00725941720.012
microtubule cytoskeleton organizationGO:00002261760.012
divalent inorganic cation homeostasisGO:00725071360.012
negative regulation of phosphorylationGO:00423261740.012
protein localization to membraneGO:00726571600.012
positive regulation of organelle organizationGO:00106381950.012
agingGO:0007568660.012
reproductive processGO:00224141060.012
Yeast
long chain fatty acid metabolic processGO:0001676300.012
posttranscriptional regulation of gene expressionGO:00106082130.012
rna splicingGO:00083801310.012
regulation of endopeptidase activityGO:00525481700.012
tissue morphogenesisGO:0048729960.012
head developmentGO:00603221080.012
organ morphogenesisGO:00098871470.012
regulation of neural precursor cell proliferationGO:200017740.012
somatic cell dna recombinationGO:001644460.012
Mouse
negative regulation of hydrolase activityGO:00513461820.012
positive regulation of apoptotic processGO:00430652460.012
negative regulation of transportGO:00510511760.012
regulation of protein catabolic processGO:00421761550.012
ion transmembrane transportGO:00342203380.012
positive regulation of catabolic processGO:00098963100.011
sulfur compound metabolic processGO:00067901010.011
mitotic recombinationGO:000631280.011
Yeast
enzyme linked receptor protein signaling pathwayGO:00071673030.011
protein polymerizationGO:0051258710.011
cellular response to radiationGO:0071478650.011
neural tube formationGO:000184130.011
reciprocal dna recombinationGO:003582540.011
protein localization to organelleGO:00333652800.011
reactive nitrogen species metabolic processGO:200105730.011
reactive oxygen species biosynthetic processGO:190340940.011
response to metal ionGO:0010038840.011
tube closureGO:006060630.011
maintenance of locationGO:00512351120.011
cellular response to organonitrogen compoundGO:00714171240.011
metal ion transportGO:00300012720.011
viral processGO:00160321460.011
negative regulation of protein metabolic processGO:00512483910.011
regulation of peptidase activityGO:00525471800.011
response to growth factorGO:00708482050.011
regulation of dephosphorylationGO:0035303960.011
nucleocytoplasmic transportGO:00069131760.011
detection of stimulusGO:0051606850.011
organonitrogen compound biosynthetic processGO:19015662000.011
regulation of double strand break repair via homologous recombinationGO:0010569110.011
regulation of purine nucleotide catabolic processGO:00331212050.011
response to axon injuryGO:004867810.011
cellular response to organic cyclic compoundGO:00714071270.011
negative regulation of cellular component movementGO:00512711060.011
positive regulation of cellular component movementGO:00512721810.011
interspecies interaction between organismsGO:00444191560.010
regulation of endothelial cell differentiationGO:004560140.010
growthGO:00400072020.010
humoral immune responseGO:0006959490.010
protein homooligomerizationGO:00512601000.010
regulation of rna splicingGO:0043484620.010
cellular lipid metabolic processGO:00442553030.010
cell fate commitmentGO:0045165270.010
Yeast
response to cytokineGO:00340972320.010
negative regulation of cell differentiationGO:00455961710.010
negative regulation of transferase activityGO:00513481240.010
positive regulation of reactive oxygen species biosynthetic processGO:190342820.010
dna duplex unwindingGO:0032508300.010
negative regulation of dna replicationGO:0008156290.010
regulation of endothelial cell proliferationGO:0001936560.010
response to other organismGO:00517072610.010
cellular response to lipidGO:00713961270.010
rhythmic behaviorGO:000762220.010
positive regulation of cell developmentGO:0010720920.010
negative regulation of cell migrationGO:00303361020.010
inorganic cation transmembrane transportGO:00986621940.010
endothelial cell proliferationGO:0001935650.010

MSH3 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
immune system diseaseDOID:29141550.123
disease of cellular proliferationDOID:145661740.116
cancerDOID:1621670.104
organ system cancerDOID:00506861640.049
female reproductive organ cancerDOID:120100.040
reproductive organ cancerDOID:193230.040
disease of metabolismDOID:00146672950.032
hematopoietic system diseaseDOID:741000.030
anemiaDOID:2355550.028
nervous system diseaseDOID:8634310.018
sensory system diseaseDOID:00501552030.018
musculoskeletal system diseaseDOID:172230.017
eye and adnexa diseaseDOID:14921500.017
endocrine gland cancerDOID:170260.014
retinal diseaseDOID:56791180.014
eye diseaseDOID:56141490.014
inherited metabolic disorderDOID:6552420.013