Homo sapiens

0 known processes

GREM2

gremlin 2

(Aliases: PRDC,DAND3,CKTSF1B2)

GREM2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular ketone metabolic processGO:0042180800.161
cellular amine metabolic processGO:0044106410.125
regulation of cellular amine metabolic processGO:0033238110.114
regulation of cellular ketone metabolic processGO:0010565500.114
lipid metabolic processGO:00066293810.110
regulation of locomotionGO:00400123290.109
regulation of cellular amino acid metabolic processGO:000652160.103
amine metabolic processGO:0009308440.103
positive regulation of cellular amino acid metabolic processGO:004576430.098
cellular amino acid metabolic processGO:00065201160.097
regulation of cellular component movementGO:00512703340.084
positive regulation of cellular amine metabolic processGO:003324070.083
cellular lipid metabolic processGO:00442553030.079
system processGO:00030083490.075
cation transportGO:00068123310.072
positive regulation of locomotionGO:00400171860.071
response to oxygen containing compoundGO:19017003690.071
g protein coupled receptor signaling pathwayGO:00071862070.070
negative regulation of multicellular organismal processGO:00512413170.070
Human
positive regulation of cellular component organizationGO:00511303760.069
positive regulation of phosphorylationGO:00423273940.065
regulation of cell differentiationGO:00455953930.065
Human
regulation of response to external stimulusGO:00321012220.064
positive regulation of protein phosphorylationGO:00019343130.064
regulation of cell motilityGO:20001452990.063
oxidation reduction processGO:00551143960.063
locomotory behaviorGO:000762610.063
positive regulation of mapk cascadeGO:00434101900.063
negative regulation of protein metabolic processGO:00512483910.063
Human
post embryonic developmentGO:000979120.062
nervous system developmentGO:00073992930.061
metal ion transportGO:00300012720.061
regulation of mapk cascadeGO:00434082620.061
ribonucleoside catabolic processGO:00424544060.058
positive regulation of cellular component movementGO:00512721810.058
signal transduction by phosphorylationGO:00230142970.057
regulation of cell migrationGO:00303342890.053
transmembrane transportGO:00550853990.053
ion transmembrane transportGO:00342203380.053
chemical homeostasisGO:00488783060.053
organophosphate catabolic processGO:00464344300.051
positive regulation of cell motilityGO:20001471770.051
mapk cascadeGO:00001652880.050
purine ribonucleoside triphosphate metabolic processGO:00092054110.050
ribonucleoside triphosphate catabolic processGO:00092033910.049
positive regulation of cell migrationGO:00303351720.048
nucleoside catabolic processGO:00091644080.048
ion homeostasisGO:00508012300.047
negative regulation of cellular protein metabolic processGO:00322693530.047
Human
regulation of transferase activityGO:00513383550.046
Human
purine containing compound catabolic processGO:00725234110.046
positive regulation of catabolic processGO:00098963100.045
purine nucleoside triphosphate metabolic processGO:00091444120.045
ras protein signal transductionGO:0007265730.045
regulation of kinase activityGO:00435493140.045
negative regulation of phosphate metabolic processGO:00459362670.044
Human
nucleoside phosphate catabolic processGO:19012924120.044
negative regulation of developmental processGO:00510932470.044
Human
cellular response to endogenous stimulusGO:00714953360.044
nucleotide catabolic processGO:00091664080.044
purine nucleoside triphosphate catabolic processGO:00091463920.043
regulation of nucleotide metabolic processGO:00061402690.043
positive regulation of transportGO:00510503360.043
glycosyl compound catabolic processGO:19016584130.043
negative regulation of cell deathGO:00605483450.042
secretionGO:00469032540.042
vesicle mediated transportGO:00161923710.042
defense responseGO:00069523150.041
regulation of system processGO:00440571010.041
purine ribonucleoside metabolic processGO:00461284370.041
regulation of anatomical structure morphogenesisGO:00226032860.041
Human
regulation of cellular component biogenesisGO:00440872810.041
purine ribonucleoside triphosphate catabolic processGO:00092073910.041
actin filament based processGO:00300292240.041
purine ribonucleoside catabolic processGO:00461303980.040
cation homeostasisGO:00550801890.040
positive regulation of immune system processGO:00026842830.040
purine nucleotide catabolic processGO:00061954050.040
negative regulation of locomotionGO:00400131180.040
ribonucleotide catabolic processGO:00092614050.040
positive regulation of protein kinase activityGO:00458601900.040
cytoplasmic transportGO:00164823790.039
nucleoside triphosphate metabolic processGO:00091414220.039
cell morphogenesisGO:00009022960.039
Human
purine nucleoside catabolic processGO:00061523980.039
ribonucleoside triphosphate metabolic processGO:00091994120.038
positive regulation of purine nucleotide metabolic processGO:19005442270.038
regulation of protein kinase activityGO:00458592890.038
taxisGO:00423301570.038
negative regulation of apoptotic processGO:00430663160.038
regulation of purine nucleotide metabolic processGO:19005422640.037
purine ribonucleotide catabolic processGO:00091544040.037
small gtpase mediated signal transductionGO:0007264780.037
response to abiotic stimulusGO:00096283360.036
nucleoside triphosphate catabolic processGO:00091433940.036
negative regulation of cell proliferationGO:00082852280.036
Human
cellular chemical homeostasisGO:00550821800.036
positive regulation of kinase activityGO:00336742040.036
cellular ion homeostasisGO:00068731680.036
negative regulation of programmed cell deathGO:00430693210.035
inorganic ion transmembrane transportGO:00986602310.035
cellular cation homeostasisGO:00300031630.035
multicellular organismal agingGO:001025930.035
negative regulation of catalytic activityGO:00430863350.035
regulation of cell cycleGO:00517263930.035
female gamete generationGO:000729220.035
secretion by cellGO:00329402260.034
determination of adult lifespanGO:000834020.034
positive regulation of developmental processGO:00510943140.034
monocarboxylic acid metabolic processGO:00327871850.034
cellular metal ion homeostasisGO:00068751460.034
biological adhesionGO:00226103310.034
negative regulation of cellular component movementGO:00512711060.033
cell developmentGO:00484683280.033
Human
cellular homeostasisGO:00197251960.033
positive regulation of nucleotide metabolic processGO:00459812300.033
positive regulation of cell proliferationGO:00082843010.033
Human
immune responseGO:00069553070.033
positive regulation of cellular catabolic processGO:00313312840.033
positive regulation of hydrolase activityGO:00513453310.032
response to lipidGO:00339932060.032
cardiovascular system developmentGO:00723582620.032
circulatory system developmentGO:00723592620.032
positive regulation of transferase activityGO:00513472270.032
Human
behaviorGO:00076101120.032
negative regulation of cellular component organizationGO:00511292350.031
metal ion homeostasisGO:00550651690.031
response to other organismGO:00517072610.031
divalent inorganic cation transportGO:00725111580.031
single organism cell adhesionGO:00986021790.031
alcohol metabolic processGO:00060661140.031
cellular response to oxygen containing compoundGO:19017012760.030
single organism cellular localizationGO:19025803320.030
growthGO:00400072020.030
peptidyl tyrosine phosphorylationGO:00181081700.030
cell projection organizationGO:00300302520.030
calcium ion homeostasisGO:00550741220.030
regulation of secretion by cellGO:19035301770.030
anatomical structure formation involved in morphogenesisGO:00486462840.030
Human
carbohydrate metabolic processGO:00059752070.029
neurogenesisGO:00220081690.029
peptidyl tyrosine modificationGO:00182121700.029
regulation of secretionGO:00510461940.029
cell adhesionGO:00071553250.029
cellular response to growth factor stimulusGO:00713631970.029
blood vessel developmentGO:00015681720.028
blood vessel morphogenesisGO:00485141620.028
carbohydrate derivative biosynthetic processGO:19011372070.028
purine nucleoside monophosphate metabolic processGO:00091261860.028
response to growth factorGO:00708482050.028
inorganic cation transmembrane transportGO:00986621940.028
adult locomotory behaviorGO:000834410.028
response to woundingGO:00096111680.028
regulation of cellular response to stressGO:00801352440.027
regulation of growthGO:00400081650.027
cellular macromolecular complex assemblyGO:00346223240.027
generation of neuronsGO:00486991520.027
sequestering of metal ionGO:0051238240.027
chemotaxisGO:00069351570.027
positive regulation of cell deathGO:00109422630.027
cell activationGO:00017752130.027
membrane organizationGO:00610242920.027
dephosphorylationGO:00163112090.026
apoptotic signaling pathwayGO:00971902680.026
nucleoside monophosphate metabolic processGO:00091231910.026
regulation of ion transportGO:00432691890.026
cation transmembrane transportGO:00986552380.026
hindbrain developmentGO:003090230.026
protein maturationGO:00516042330.026
enzyme linked receptor protein signaling pathwayGO:00071673030.026
Human Mouse
regulation of behaviorGO:0050795820.025
divalent inorganic cation homeostasisGO:00725071360.025
maintenance of locationGO:00512351120.025
response to biotic stimulusGO:00096072760.025
organ morphogenesisGO:00098871470.025
Human
negative regulation of phosphorus metabolic processGO:00105632670.025
Human
cell growthGO:00160491600.025
cellular divalent inorganic cation homeostasisGO:00725031280.025
cellular calcium ion homeostasisGO:00068741170.025
fatty acid metabolic processGO:00066311150.025
response to hormoneGO:00097251750.025
neuron differentiationGO:00301821380.025
response to external biotic stimulusGO:00432072610.025
regulation of homeostatic processGO:00328441210.025
oogenesisGO:004847720.025
sequestering of calcium ionGO:0051208170.024
regulation of establishment of protein localizationGO:00702012420.024
regenerationGO:003109940.024
positive regulation of purine nucleotide catabolic processGO:00331231850.024
actin cytoskeleton organizationGO:00300362070.024
calcium ion transportGO:00068161470.024
regulation of transmembrane transportGO:00347621390.023
protein processingGO:00164852260.023
regulation of ion transmembrane transportGO:00347651320.023
negative regulation of protein modification processGO:00314002000.023
Human
motor neuron axon guidanceGO:000804520.023
cytosolic calcium ion homeostasisGO:0051480890.023
regulation of protein localizationGO:00328802960.023
regulation of cell cycle processGO:00105642660.023
divalent metal ion transportGO:00708381520.023
regulation of proteolysisGO:00301622930.023
single organism carbohydrate metabolic processGO:00447231930.023
cellular response to dna damage stimulusGO:00069743790.023
organic hydroxy compound metabolic processGO:19016151470.023
regulation of hormone levelsGO:00108171250.023
ameboidal type cell migrationGO:00016671350.023
hematopoietic or lymphoid organ developmentGO:00485341860.023
epithelium developmentGO:00604292270.023
segmentationGO:003528240.023
organonitrogen compound biosynthetic processGO:19015662000.023
neuromuscular junction developmentGO:000752830.022
muscle system processGO:0003012810.022
regulation of body fluid levelsGO:0050878990.022
single organism membrane organizationGO:00448022680.022
neurological system processGO:00508771630.022
positive regulation of nucleotide catabolic processGO:00308131850.022
regulation of response to woundingGO:19030341010.022
ribonucleoside monophosphate metabolic processGO:00091611870.022
cellular component morphogenesisGO:00329893140.022
Human
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.022
positive regulation of cell differentiationGO:00455972110.022
memoryGO:000761330.022
regulation of cell projection organizationGO:00313441070.022
positive regulation of apoptotic processGO:00430652460.022
mitotic cell cycleGO:00002783260.022
purine ribonucleoside monophosphate metabolic processGO:00091671860.022
organophosphate biosynthetic processGO:00904071630.022
nitrogen compound transportGO:00717051910.022
muscle contractionGO:0006936730.022
immune system developmentGO:00025201950.022
cellular protein complex assemblyGO:00436231880.021
vasculature developmentGO:00019441810.021
negative regulation of cellular amino acid metabolic processGO:004576320.021
regulation of cell developmentGO:00602841610.021
Human
regulation of cell morphogenesisGO:00226041530.021
Human
circulatory system processGO:00030131130.021
negative regulation of cellular amine metabolic processGO:003323930.021
gtp catabolic processGO:00061842370.021
rho protein signal transductionGO:0007266260.021
response to organic cyclic compoundGO:00140702040.021
regulation of protein transportGO:00512232130.021
metencephalon developmentGO:002203720.021
positive regulation of nucleoside metabolic processGO:00459791860.021
actin filament based movementGO:0030048170.021
positive regulation of organelle organizationGO:00106381950.021
regulation of cytoskeleton organizationGO:00514931770.021
positive regulation of synaptic transmissionGO:005080640.021
circadian behaviorGO:004851220.021
small molecule biosynthetic processGO:00442831570.020
epithelial cell proliferationGO:00506731280.020
regulation of nucleoside metabolic processGO:00091182090.020
negative regulation of response to external stimulusGO:0032102830.020
negative regulation of phosphorylationGO:00423261740.020
Human
regulation of purine nucleotide catabolic processGO:00331212050.020
negative regulation of cell migrationGO:00303361020.020
atp metabolic processGO:00460341760.020
negative regulation of cell differentiationGO:00455961710.020
regulation of protein serine threonine kinase activityGO:00719001790.020
sensory perception of painGO:001923340.020
ossificationGO:00015031210.020
Human
guanosine containing compound catabolic processGO:19010692390.020
peripheral nervous system developmentGO:000742220.020
regulation of sequence specific dna binding transcription factor activityGO:00510902110.020
blood coagulationGO:0007596760.020
spinal cord developmentGO:002151040.020
protein catabolic processGO:00301633250.020
negative regulation of intracellular signal transductionGO:19025321830.020
innate immune responseGO:00450871780.019
anion transportGO:00068201610.019
mitotic cell cycle processGO:19030472860.019
central nervous system developmentGO:00074171230.019
reactive oxygen species metabolic processGO:0072593750.019
cellular macromolecule catabolic processGO:00442653800.019
activation of protein kinase activityGO:0032147900.019
regulation of cell growthGO:00015581350.019
protein localization to membraneGO:00726571600.019
regulation of cytokine productionGO:00018172320.019
cell chemotaxisGO:00603261120.019
negative regulation of hydrolase activityGO:00513461820.019
gtp metabolic processGO:00460392390.019
cell cell signalingGO:00072671550.019
forelimb morphogenesisGO:003513640.019
regulation of axon guidanceGO:190266730.019
positive regulation of programmed cell deathGO:00430682490.019
guanosine containing compound metabolic processGO:19010682440.019
regulation of defense responseGO:00313471540.019
cardiac muscle cell contractionGO:008600340.019
muscle structure developmentGO:0061061980.019
reactive oxygen species biosynthetic processGO:190340940.019
associative learningGO:000830610.019
protein ubiquitinationGO:00165673140.019
regulation of ras protein signal transductionGO:00465781550.018
protein localization to organelleGO:00333652800.018
regulation of ion homeostasisGO:2000021730.018
tissue migrationGO:00901301190.018
regulation of endopeptidase activityGO:00525481700.018
positive regulation of secretion by cellGO:19035321080.018
rhythmic behaviorGO:000762220.018
regulation of metal ion transportGO:00109591200.018
regulation of actin filament based processGO:00329701410.018
positive regulation of cellular component biogenesisGO:00440891580.018
regulation of vesicle mediated transportGO:00606271300.018
nucleoside phosphate biosynthetic processGO:19012931090.018
regulation of gtpase activityGO:00430871800.018
regulation of intracellular transportGO:00323861950.018
chromatin organizationGO:00063253510.018
immune effector processGO:00022521590.018
actin mediated cell contractionGO:0070252120.018
response to hypoxiaGO:0001666960.018
regulation of reactive oxygen species biosynthetic processGO:190342630.018
second messenger mediated signalingGO:0019932780.018
ribonucleoside monophosphate catabolic processGO:00091581580.017
regulation of protein maturationGO:19033171500.017
regulation of erk1 and erk2 cascadeGO:0070372990.017
regulation of protein processingGO:00706131500.017
protein oligomerizationGO:00512591730.017
negative regulation of transportGO:00510511760.017
regulation of membrane potentialGO:0042391950.017
regulation of cell adhesionGO:00301551660.017
negative regulation of cell cycleGO:00457861930.017
negative regulation of cell motilityGO:20001461040.017
endomembrane system organizationGO:00102561960.017
protein modification by small protein conjugationGO:00324463420.017
positive regulation of cytosolic calcium ion concentrationGO:0007204820.017
epithelium migrationGO:00901321190.017
nucleoside monophosphate catabolic processGO:00091251590.017
intracellular protein transportGO:00068862700.017
purine nucleoside monophosphate catabolic processGO:00091281580.017
positive regulation of peptidyl tyrosine phosphorylationGO:0050731850.017
negative regulation of protein phosphorylationGO:00019331400.017
Human
regulation of epithelial cell proliferationGO:00506781130.017
positive regulation of secretionGO:00510471160.017
regulation of small gtpase mediated signal transductionGO:00510561560.017
cellular response to organonitrogen compoundGO:00714171240.017
posttranscriptional regulation of gene expressionGO:00106082130.017
organ formationGO:004864530.017
positive regulation of chemotaxisGO:0050921570.017
regulation of protein complex assemblyGO:00432541470.017
regulation of reactive oxygen species metabolic processGO:2000377410.017
hemopoiesisGO:00300971800.017
cell part morphogenesisGO:00329901370.017
lipid catabolic processGO:0016042840.017
neuron developmentGO:00486661130.017
purine ribonucleoside monophosphate catabolic processGO:00091691580.017
atp catabolic processGO:00062001570.017
epithelial cell differentiationGO:00308551410.016
reactive nitrogen species metabolic processGO:200105730.016
coagulationGO:0050817780.016
behavioral response to ethanolGO:004814920.016
cytokine productionGO:00018162470.016
negative regulation of organelle organizationGO:00106391260.016
actin filament organizationGO:00070151280.016
proteolysis involved in cellular protein catabolic processGO:00516032440.016
neuron projection developmentGO:00311751060.016
lipid biosynthetic processGO:00086101770.016
response to decreased oxygen levelsGO:0036293960.016
chromatin modificationGO:00165682980.016
matingGO:000761810.016
startle responseGO:000196430.016
angiogenesisGO:00015251470.016
erk1 and erk2 cascadeGO:00703711040.016
sensory perception of smellGO:000760820.016
cellular protein catabolic processGO:00442572610.016
cell projection morphogenesisGO:00488581290.016
regulation of chemotaxisGO:0050920740.016
cell divisionGO:00513011680.016
cerebellum developmentGO:002154920.016
blastoderm segmentationGO:000735020.016
head developmentGO:00603221080.016
regulation of dna metabolic processGO:00510521530.016
Human
response to oxygen levelsGO:00704821000.016
morphogenesis of embryonic epitheliumGO:001633140.016
sex determinationGO:000753030.016
brain developmentGO:0007420970.016
regulation of peptidyl tyrosine phosphorylationGO:00507301080.015
positive regulation of gtpase activityGO:00435471660.015
regulation of nucleotide catabolic processGO:00308112050.015
response to inorganic substanceGO:00100351270.015
response to organonitrogen compoundGO:00102431560.015
lipid transportGO:0006869900.015
protein targetingGO:00066051870.015
epithelial cell migrationGO:00106311190.015
positive regulation of protein transportGO:00512221350.015
regulation of immune responseGO:00507762010.015
positive regulation of gtp catabolic processGO:00331261660.015
nerve developmentGO:002167540.015
cell fate determinationGO:000170930.015
response to virusGO:00096151260.015
response to axon injuryGO:004867810.015
multicellular organismal response to stressGO:003355510.015
thymus developmentGO:004853830.015
negative regulation of axonogenesisGO:005077140.015
single organismal cell cell adhesionGO:00163371480.015
regulation of vasculature developmentGO:1901342970.015
embryonic epithelial tube formationGO:000183840.015
cellular response to cytokine stimulusGO:00713451810.015
Mouse
sulfur compound metabolic processGO:00067901010.015
compound eye developmentGO:004874910.015
regulation of gtp catabolic processGO:00331241800.015
positive regulation of erk1 and erk2 cascadeGO:0070374750.015
endocytosisGO:00068971590.015
salivary gland morphogenesisGO:000743540.015
regulation of synaptic plasticityGO:004816730.015
regulation of cardiac muscle cell proliferationGO:006004340.015
leukocyte migrationGO:00509001070.015
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.015
morphogenesis of a polarized epitheliumGO:000173830.015
anterior posterior axis specificationGO:000994820.015
cell cycle phase transitionGO:00447701730.014
cellular response to nitrogen compoundGO:19016991440.014
negative regulation of protein maturationGO:19033181420.014
regulation of axon extension involved in axon guidanceGO:004884120.014
leukocyte activationGO:00453211640.014
spermatid differentiationGO:004851540.014
regulation of apoptotic signaling pathwayGO:20012331750.014
multi organism cellular processGO:00447641560.014
positive regulation of ras gtpase activityGO:00323201170.014
midgut developmentGO:000749410.014
positive regulation of reactive oxygen species metabolic processGO:2000379240.014
regulation of transporter activityGO:0032409820.014
response to cytokineGO:00340972320.014
Mouse
interspecies interaction between organismsGO:00444191560.014
positive regulation of reactive oxygen species biosynthetic processGO:190342820.014
positive regulation of vasoconstrictionGO:004590730.014
nucleotide biosynthetic processGO:00091651090.014
visual behaviorGO:000763220.014
negative regulation of gliogenesisGO:001401430.014
steroid metabolic processGO:0008202940.014
negative regulation of protein processingGO:00109551420.014
ribose phosphate biosynthetic processGO:0046390820.014
mitotic cell cycle phase transitionGO:00447721620.014
glycerolipid metabolic processGO:00464861070.014
positive regulation of response to external stimulusGO:0032103880.014
positive regulation of protein serine threonine kinase activityGO:00719021190.014
histone modificationGO:00165702510.014
limbic system developmentGO:002176130.014
phospholipid metabolic processGO:0006644990.014
regulation of lipid metabolic processGO:0019216960.014
regulation of peptidase activityGO:00525471800.014
regulation of neurogenesisGO:0050767820.014
response to metal ionGO:0010038840.014
nucleocytoplasmic transportGO:00069131760.013
cellular response to organic cyclic compoundGO:00714071270.013
regulation of mitotic cell cycleGO:00073461890.013
response to nitrogen compoundGO:19016981840.013
regulation of epithelial cell migrationGO:0010632930.013
embryonic forelimb morphogenesisGO:003511540.013
epithelial tube branching involved in lung morphogenesisGO:006044140.013
regulation of bindingGO:00510981110.013
Mouse
lung alveolus developmentGO:004828640.013
regulation of heart growthGO:006042040.013
regulation of neural precursor cell proliferationGO:200017740.013
protein autophosphorylationGO:00467771230.013
cyclic nucleotide metabolic processGO:0009187820.013
organic acid biosynthetic processGO:0016053970.013
oocyte developmentGO:004859910.013
camp metabolic processGO:0046058610.013
somitogenesisGO:000175620.013
organic anion transportGO:00157111030.013
cell substrate adhesionGO:00315891320.013
modification dependent macromolecule catabolic processGO:00436322120.013
wound healingGO:00420601150.013
regulation of protein catabolic processGO:00421761550.013
dna repairGO:00062811980.013
mitochondrion organizationGO:00070051560.013
neurotransmitter secretionGO:000726940.013
hemostasisGO:0007599760.013
extrinsic apoptotic signaling pathwayGO:00971911190.013
glial cell migrationGO:000834740.013
syncytium formation by plasma membrane fusionGO:000076820.013
neuroblast proliferationGO:000740540.013
blood circulationGO:00080151130.013
activation of transmembrane receptor protein tyrosine kinase activityGO:000717140.013
proteasomal protein catabolic processGO:00104981760.013
negative regulation of proteolysisGO:00458611320.013
cerebral cortex cell migrationGO:002179530.013

GREM2 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
musculoskeletal system diseaseDOID:172230.036
disease of metabolismDOID:00146672950.034
cardiovascular system diseaseDOID:12871060.032
inherited metabolic disorderDOID:6552420.027
central nervous system diseaseDOID:3311860.019
nervous system diseaseDOID:8634310.019
sensory system diseaseDOID:00501552030.018
disease of cellular proliferationDOID:145661740.017
cancerDOID:1621670.017
organ system cancerDOID:00506861640.016
connective tissue diseaseDOID:651090.015
muscular diseaseDOID:00800001140.014
muscle tissue diseaseDOID:661130.014
eye and adnexa diseaseDOID:14921500.014
eye diseaseDOID:56141490.014
bone diseaseDOID:0080001880.014
neurodegenerative diseaseDOID:12891020.013