Homo sapiens

0 known processes

PNPLA1

patatin-like phospholipase domain containing 1

(Aliases: MGC119319,dJ50J22.1,MGC119320,FLJ38755,MGC119321)

PNPLA1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
post embryonic developmentGO:000979120.061
cellular amino acid metabolic processGO:00065201160.060
cellular ketone metabolic processGO:0042180800.049
defense responseGO:00069523150.048
amine metabolic processGO:0009308440.046
immune responseGO:00069553070.046
regulation of cellular amino acid metabolic processGO:000652160.045
system processGO:00030083490.045
positive regulation of cellular amino acid metabolic processGO:004576430.040
cellular amine metabolic processGO:0044106410.039
regulation of cellular ketone metabolic processGO:0010565500.039
negative regulation of protein metabolic processGO:00512483910.039
positive regulation of immune system processGO:00026842830.038
multicellular organismal agingGO:001025930.038
Fly
determination of adult lifespanGO:000834020.037
Fly
regulation of cellular amine metabolic processGO:0033238110.036
negative regulation of cellular protein metabolic processGO:00322693530.036
biological adhesionGO:00226103310.034
response to other organismGO:00517072610.034
response to external biotic stimulusGO:00432072610.032
locomotory behaviorGO:000762610.032
cation transportGO:00068123310.032
response to oxygen containing compoundGO:19017003690.031
cytokine productionGO:00018162470.031
regulation of cytokine productionGO:00018172320.031
regulation of cell differentiationGO:00455953930.031
female gamete generationGO:000729220.031
positive regulation of cellular amine metabolic processGO:003324070.031
positive regulation of transportGO:00510503360.030
segmentationGO:003528240.029
regulation of immune responseGO:00507762010.029
vesicle mediated transportGO:00161923710.029
cellular lipid metabolic processGO:00442553030.028
Human Fly
regulation of proteolysisGO:00301622930.028
ribonucleoside triphosphate metabolic processGO:00091994120.028
nucleoside triphosphate metabolic processGO:00091414220.028
chemical homeostasisGO:00488783060.028
Fly
regulation of response to external stimulusGO:00321012220.028
response to biotic stimulusGO:00096072760.028
positive regulation of phosphorylationGO:00423273940.028
organophosphate catabolic processGO:00464344300.027
purine ribonucleoside metabolic processGO:00461284370.027
oogenesisGO:004847720.027
purine ribonucleoside catabolic processGO:00461303980.027
negative regulation of multicellular organismal processGO:00512413170.027
positive regulation of hydrolase activityGO:00513453310.027
negative regulation of catalytic activityGO:00430863350.027
regulation of transferase activityGO:00513383550.027
glycosyl compound catabolic processGO:19016584130.027
ras protein signal transductionGO:0007265730.026
cytoplasmic transportGO:00164823790.026
purine nucleoside triphosphate metabolic processGO:00091444120.026
innate immune responseGO:00450871780.026
protein catabolic processGO:00301633250.026
regulation of protein localizationGO:00328802960.026
cellular macromolecule catabolic processGO:00442653800.025
nucleotide catabolic processGO:00091664080.025
cell adhesionGO:00071553250.025
regulation of secretionGO:00510461940.025
negative regulation of cell deathGO:00605483450.025
purine containing compound catabolic processGO:00725234110.025
regulation of cell cycleGO:00517263930.025
neurological system processGO:00508771630.025
small molecule biosynthetic processGO:00442831570.025
purine nucleoside triphosphate catabolic processGO:00091463920.025
purine ribonucleotide catabolic processGO:00091544040.025
ribonucleoside triphosphate catabolic processGO:00092033910.025
leukocyte activationGO:00453211640.024
negative regulation of apoptotic processGO:00430663160.024
ribonucleoside catabolic processGO:00424544060.024
carboxylic acid biosynthetic processGO:0046394970.024
purine ribonucleoside triphosphate metabolic processGO:00092054110.024
positive regulation of immune responseGO:00507781590.024
positive regulation of cell deathGO:00109422630.024
ribonucleotide catabolic processGO:00092614050.024
signal transduction by phosphorylationGO:00230142970.024
protein maturationGO:00516042330.023
negative regulation of programmed cell deathGO:00430693210.023
positive regulation of cellular component organizationGO:00511303760.023
nucleoside catabolic processGO:00091644080.023
small gtpase mediated signal transductionGO:0007264780.023
nucleoside phosphate catabolic processGO:19012924120.023
organic acid biosynthetic processGO:0016053970.023
purine nucleoside catabolic processGO:00061523980.023
purine ribonucleoside triphosphate catabolic processGO:00092073910.023
regenerationGO:003109940.023
nervous system developmentGO:00073992930.023
transmembrane transportGO:00550853990.023
single organism membrane organizationGO:00448022680.023
neuromuscular junction developmentGO:000752830.023
positive regulation of apoptotic processGO:00430652460.023
lipid biosynthetic processGO:00086101770.022
Human
positive regulation of catabolic processGO:00098963100.022
Human
purine nucleotide catabolic processGO:00061954050.022
lipid metabolic processGO:00066293810.022
Human Fly
regulation of protein kinase activityGO:00458592890.022
positive regulation of cell proliferationGO:00082843010.022
negative regulation of phosphate metabolic processGO:00459362670.022
positive regulation of cytokine productionGO:00018191670.022
regulation of kinase activityGO:00435493140.022
response to abiotic stimulusGO:00096283360.022
cell activationGO:00017752130.022
nucleoside triphosphate catabolic processGO:00091433940.022
organonitrogen compound biosynthetic processGO:19015662000.022
positive regulation of programmed cell deathGO:00430682490.022
anion transportGO:00068201610.022
secretionGO:00469032540.021
regulation of cellular component movementGO:00512703340.021
cellular protein catabolic processGO:00442572610.021
regulation of establishment of protein localizationGO:00702012420.021
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.021
apoptotic signaling pathwayGO:00971902680.021
monocarboxylic acid metabolic processGO:00327871850.021
neuron fate commitmentGO:004866320.021
protein processingGO:00164852260.021
blastoderm segmentationGO:000735020.021
actin filament based processGO:00300292240.020
cell fate determinationGO:000170930.020
reactive oxygen species metabolic processGO:0072593750.020
ion homeostasisGO:00508012300.020
cellular response to oxygen containing compoundGO:19017012760.020
cellular component morphogenesisGO:00329893140.020
regulation of protein transportGO:00512232130.020
lymphocyte activationGO:00466491330.020
positive regulation of developmental processGO:00510943140.020
regulation of cellular response to stressGO:00801352440.020
negative regulation of cellular amino acid metabolic processGO:004576320.020
negative regulation of cellular amine metabolic processGO:003323930.020
secretion by cellGO:00329402260.020
response to cytokineGO:00340972320.020
negative regulation of phosphorus metabolic processGO:00105632670.020
cellular homeostasisGO:00197251960.020
negative regulation of cell proliferationGO:00082852280.019
regulation of secretion by cellGO:19035301770.019
positive regulation of transferase activityGO:00513472270.019
cardiac muscle cell contractionGO:008600340.019
metal ion transportGO:00300012720.019
protein modification by small protein conjugationGO:00324463420.019
cellular response to dna damage stimulusGO:00069743790.019
divalent inorganic cation transportGO:00725111580.019
positive regulation of cellular catabolic processGO:00313312840.019
Human
oxidation reduction processGO:00551143960.019
single organism cellular localizationGO:19025803320.019
regulation of endopeptidase activityGO:00525481700.019
cell morphogenesisGO:00009022960.019
negative regulation of protein modification processGO:00314002000.019
sensory perceptionGO:00076001030.019
regulation of leukocyte activationGO:00026941150.018
cellular response to cytokine stimulusGO:00713451810.018
mapk cascadeGO:00001652880.018
defense response to other organismGO:00985421290.018
rho protein signal transductionGO:0007266260.018
membrane organizationGO:00610242920.018
reactive oxygen species biosynthetic processGO:190340940.018
cation homeostasisGO:00550801890.018
regulation of cell activationGO:00508651250.018
regulation of intracellular transportGO:00323861950.018
response to bacteriumGO:00096171440.018
anatomical structure formation involved in morphogenesisGO:00486462840.018
mitotic cell cycleGO:00002783260.018
protein localization to organelleGO:00333652800.018
hindbrain developmentGO:003090230.018
regulation of anatomical structure morphogenesisGO:00226032860.018
cell developmentGO:00484683280.017
photoreceptor cell differentiationGO:004653020.017
regulation of mapk cascadeGO:00434082620.017
maintenance of locationGO:00512351120.017
Human Fly
single organism cell adhesionGO:00986021790.017
oocyte developmentGO:004859910.017
negative regulation of cellular component organizationGO:00511292350.017
regulation of peptidase activityGO:00525471800.017
protein ubiquitinationGO:00165673140.017
cellular ion homeostasisGO:00068731680.017
dephosphorylationGO:00163112090.017
inorganic cation transmembrane transportGO:00986621940.017
oocyte differentiationGO:000999420.017
actin filament based movementGO:0030048170.017
anterior posterior axis specificationGO:000994820.017
regulation of defense responseGO:00313471540.017
proteolysis involved in cellular protein catabolic processGO:00516032440.017
protein oligomerizationGO:00512591730.017
spermatid differentiationGO:004851540.017
immune system developmentGO:00025201950.017
adult locomotory behaviorGO:000834410.017
inorganic ion transmembrane transportGO:00986602310.016
regulation of purine nucleotide metabolic processGO:19005422640.016
immune effector processGO:00022521590.016
regulation of cell cycle processGO:00105642660.016
single organismal cell cell adhesionGO:00163371480.016
cellular macromolecular complex assemblyGO:00346223240.016
cell projection organizationGO:00300302520.016
regulation of cellular component biogenesisGO:00440872810.016
negative regulation of hydrolase activityGO:00513461820.016
reactive nitrogen species metabolic processGO:200105730.016
nitrogen compound transportGO:00717051910.016
intracellular protein transportGO:00068862700.016
enzyme linked receptor protein signaling pathwayGO:00071673030.016
response to lipidGO:00339932060.016
positive regulation of protein phosphorylationGO:00019343130.016
positive regulation of cell differentiationGO:00455972110.016
peripheral nervous system developmentGO:000742220.016
carbohydrate derivative biosynthetic processGO:19011372070.016
response to fungusGO:000962040.016
carbohydrate metabolic processGO:00059752070.016
associative learningGO:000830610.016
negative regulation of phosphorylationGO:00423261740.016
regulation of protein catabolic processGO:00421761550.016
metencephalon developmentGO:002203720.016
fatty acid metabolic processGO:00066311150.015
hemopoiesisGO:00300971800.015
chromatin organizationGO:00063253510.015
negative regulation of cell cycleGO:00457861930.015
epithelium developmentGO:00604292270.015
cation transmembrane transportGO:00986552380.015
positive regulation of nucleotide metabolic processGO:00459812300.015
cellular response to lipidGO:00713961270.015
negative regulation of cytokine productionGO:0001818820.015
organelle assemblyGO:00709251760.015
release of cytoplasmic sequestered nf kappabGO:000858840.015
compound eye developmentGO:004874910.015
detection of stimulusGO:0051606850.015
negative regulation of transportGO:00510511760.015
positive regulation of mapk cascadeGO:00434101900.015
regulation of lymphocyte activationGO:00512491030.015
regulation of sequence specific dna binding transcription factor activityGO:00510902110.015
organ formationGO:004864530.015
negative regulation of intracellular signal transductionGO:19025321830.015
regulation of cell adhesionGO:00301551660.015
purine ribonucleoside monophosphate metabolic processGO:00091671860.015
actin cytoskeleton organizationGO:00300362070.015
posttranscriptional regulation of gene expressionGO:00106082130.015
guanosine containing compound catabolic processGO:19010692390.015
metal ion homeostasisGO:00550651690.015
ion transmembrane transportGO:00342203380.014
actin mediated cell contractionGO:0070252120.014
mitotic cell cycle processGO:19030472860.014
endomembrane system organizationGO:00102561960.014
cellular metal ion homeostasisGO:00068751460.014
regulation of cell developmentGO:00602841610.014
spinal cord developmentGO:002151040.014
morphogenesis of embryonic epitheliumGO:001633140.014
regulation of locomotionGO:00400123290.014
regulation of cysteine type endopeptidase activityGO:20001161270.014
negative regulation of protein maturationGO:19033181420.014
generation of neuronsGO:00486991520.014
regulation of cytoplasmic transportGO:19036491490.014
spermatid developmentGO:000728640.014
positive regulation of protein transportGO:00512221350.014
neurotransmitter secretionGO:000726940.014
regulation of ion transportGO:00432691890.014
positive regulation of protein kinase activityGO:00458601900.014
regulation of protein maturationGO:19033171500.014
negative regulation of immune system processGO:00026831360.014
ribonucleoside monophosphate metabolic processGO:00091611870.014
pituitary gland developmentGO:002198320.014
regulation of protein processingGO:00706131500.014
response to organic cyclic compoundGO:00140702040.014
purine nucleoside monophosphate metabolic processGO:00091261860.014
regulation of apoptotic signaling pathwayGO:20012331750.014
atp metabolic processGO:00460341760.014
calcium ion transportGO:00068161470.014
regulation of synaptic plasticityGO:004816730.014
positive regulation of kinase activityGO:00336742040.014
regulation of cell motilityGO:20001452990.014
positive regulation of secretion by cellGO:19035321080.014
positive regulation of organelle organizationGO:00106381950.014
memoryGO:000761330.014
histone modificationGO:00165702510.014
response to radiationGO:00093141510.013
modification dependent protein catabolic processGO:00199412090.013
regulation of immune effector processGO:0002697910.013
nucleoside monophosphate metabolic processGO:00091231910.013
monocarboxylic acid biosynthetic processGO:0072330670.013
regulation of purine nucleotide catabolic processGO:00331212050.013
cellular chemical homeostasisGO:00550821800.013
modification dependent macromolecule catabolic processGO:00436322120.013
negative regulation of protein processingGO:00109551420.013
t cell activationGO:0042110990.013
cell growthGO:00160491600.013
growthGO:00400072020.013
central nervous system developmentGO:00074171230.013
regulation of reactive oxygen species biosynthetic processGO:190342630.013
response to nitrogen compoundGO:19016981840.013
divalent metal ion transportGO:00708381520.013
positive regulation of proteolysisGO:00458621420.013
neurogenesisGO:00220081690.013
syncytium formation by plasma membrane fusionGO:000076820.013
negative regulation of proteolysisGO:00458611320.013
guanosine containing compound metabolic processGO:19010682440.013
divalent inorganic cation homeostasisGO:00725071360.013
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.013
tissue regenerationGO:004224630.013
positive regulation of synaptic transmissionGO:005080640.013
cellular response to endogenous stimulusGO:00714953360.013
calcium ion homeostasisGO:00550741220.013
circadian behaviorGO:004851220.013
response to woundingGO:00096111680.013
immune response regulating signaling pathwayGO:0002764970.013
sensory perception of painGO:001923340.013
activation of immune responseGO:00022531140.013
protein targetingGO:00066051870.013
proteasomal protein catabolic processGO:00104981760.013
sequestering of metal ionGO:0051238240.013
i kappab kinase nf kappab signalingGO:00072491660.013
chromatin modificationGO:00165682980.013
cardiovascular system developmentGO:00723582620.013
regulation of cytoskeleton organizationGO:00514931770.013
positive regulation of purine nucleotide metabolic processGO:19005442270.013
regulation of cell migrationGO:00303342890.013
regulation of nucleotide catabolic processGO:00308112050.013
limbic system developmentGO:002176130.013
organic anion transportGO:00157111030.013
circulatory system developmentGO:00723592620.013
negative regulation of protein phosphorylationGO:00019331400.013
regulation of innate immune responseGO:0045088970.013
response to molecule of bacterial originGO:0002237820.013
regulation of neural precursor cell proliferationGO:200017740.013
single organism carbohydrate metabolic processGO:00447231930.013
positive regulation of nucleotide catabolic processGO:00308131850.013
regulation of protein serine threonine kinase activityGO:00719001790.013
regulation of nucleotide metabolic processGO:00061402690.013
wnt signaling pathwayGO:00160551560.012
cellular calcium ion homeostasisGO:00068741170.012
cell cycle phase transitionGO:00447701730.012
ubiquitin dependent protein catabolic processGO:00065112060.012
symbiosis encompassing mutualism through parasitismGO:00444031560.012
mitochondrion organizationGO:00070051560.012
nucleocytoplasmic transportGO:00069131760.012
regulation of homeostatic processGO:00328441210.012
defense response to fungusGO:005083240.012
sequestering of calcium ionGO:0051208170.012
regulation of growthGO:00400081650.012
immune response activating signal transductionGO:0002757900.012
hematopoietic or lymphoid organ developmentGO:00485341860.012
inner ear morphogenesisGO:004247240.012
gtp metabolic processGO:00460392390.012
microtubule based processGO:00070172100.012
positive regulation of purine nucleotide catabolic processGO:00331231850.012
regulation of nucleoside metabolic processGO:00091182090.012
atp catabolic processGO:00062001570.012
epithelial cell differentiationGO:00308551410.012
anterior posterior axis specification embryoGO:000859520.012
positive regulation of nucleoside metabolic processGO:00459791860.012
cellular protein complex assemblyGO:00436231880.012
regulation of i kappab kinase nf kappab signalingGO:00431221620.012
positive regulation of leukocyte activationGO:0002696800.012
positive regulation of secretionGO:00510471160.012
gtp catabolic processGO:00061842370.012
organophosphate biosynthetic processGO:00904071630.012
detection of muramyl dipeptideGO:003249810.012
negative regulation of cell differentiationGO:00455961710.012
rhythmic behaviorGO:000762220.012
regulation of wnt signaling pathwayGO:00301111230.012
regulation of response to woundingGO:19030341010.012
regulation of cell morphogenesisGO:00226041530.012
regulation of reactive oxygen species metabolic processGO:2000377410.012
cell divisionGO:00513011680.012
cellular cation homeostasisGO:00300031630.012
head developmentGO:00603221080.012
positive regulation of cell migrationGO:00303351720.012
visual behaviorGO:000763220.012
positive regulation of mhc class i biosynthetic processGO:004534540.012
somitogenesisGO:000175620.012
negative regulation of response to external stimulusGO:0032102830.012
glial cell migrationGO:000834740.012
regulation of ras protein signal transductionGO:00465781550.012
cellular divalent inorganic cation homeostasisGO:00725031280.012
protein localization to membraneGO:00726571600.012
positive regulation of gtpase activityGO:00435471660.012
myoblast fusionGO:000752010.012
response to axon injuryGO:004867810.012
covalent chromatin modificationGO:00165692540.012
cardiac muscle contractionGO:0060048340.012
cell type specific apoptotic processGO:00972851250.012
protein acylationGO:00435431380.012
rna processingGO:00063962550.012
response to growth factorGO:00708482050.012
organic hydroxy compound metabolic processGO:19016151470.012
regulation of mitotic cell cycleGO:00073461890.012
lipid localizationGO:00108761060.012
Human Fly
defense response to bacteriumGO:0042742630.011
regulation of small gtpase mediated signal transductionGO:00510561560.011
intrinsic apoptotic signaling pathwayGO:00971931270.011
regulation of multi organism processGO:00439001570.011
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.011
matingGO:000761810.011
regulation of vesicle mediated transportGO:00606271300.011
neuroblast proliferationGO:000740540.011
positive regulation of cell activationGO:0050867810.011
purine ribonucleoside monophosphate catabolic processGO:00091691580.011
tripartite regional subdivisionGO:000735120.011
nucleoside monophosphate catabolic processGO:00091251590.011
regulation of cell growthGO:00015581350.011
meiosis iGO:000712740.011
positive regulation of innate immune responseGO:0045089790.011
regulation of intracellular protein transportGO:00331571230.011
cellular response to abiotic stimulusGO:00712141170.011
negative regulation of catabolic processGO:00098951040.011
establishment of protein localization to organelleGO:00725941720.011
negative regulation of developmental processGO:00510932470.011
regulation of dna metabolic processGO:00510521530.011
protein secretionGO:0009306980.011
endocytosisGO:00068971590.011
nuclear transportGO:00511691790.011
dna repairGO:00062811980.011
purine nucleoside monophosphate catabolic processGO:00091281580.011
positive regulation of gtp catabolic processGO:00331261660.011
epidermis morphogenesisGO:004873030.011
inflammatory responseGO:0006954790.011
mitotic cell cycle phase transitionGO:00447721620.011
interspecies interaction between organismsGO:00444191560.011
response to hormoneGO:00097251750.011
response to virusGO:00096151260.011
embryonic epithelial tube formationGO:000183840.011
ribonucleoside monophosphate catabolic processGO:00091581580.011
negative regulation of alpha beta t cell activationGO:004663630.011
protein autophosphorylationGO:00467771230.011
motor neuron axon guidanceGO:000804520.011
alpha amino acid metabolic processGO:1901605720.011
regulation of gtpase activityGO:00430871800.011
regulation of protein secretionGO:0050708860.011
sex determinationGO:000753030.010
cell part morphogenesisGO:00329901370.010
response to organonitrogen compoundGO:00102431560.010
lipid transportGO:0006869900.010
microtubule cytoskeleton organizationGO:00002261760.010
response to inorganic substanceGO:00100351270.010
regulation of t cell activationGO:0050863770.010
tube closureGO:006060630.010
neuron differentiationGO:00301821380.010
post embryonic organ developmentGO:004856910.010
peptidyl tyrosine phosphorylationGO:00181081700.010
cellular response to organic cyclic compoundGO:00714071270.010
negative regulation of growthGO:0045926970.010
sulfur compound metabolic processGO:00067901010.010
regulation of meiotic cell cycleGO:005144540.010
cell projection morphogenesisGO:00488581290.010
negative regulation of transferase activityGO:00513481240.010
forebrain generation of neuronsGO:002187230.010
small molecule catabolic processGO:0044282920.010
regulation of meiosisGO:004002030.010
regulation of actin filament based processGO:00329701410.010
fatty acid biosynthetic processGO:0006633460.010
positive regulation of reactive oxygen species biosynthetic processGO:190342820.010
positive regulation of i kappab kinase nf kappab signalingGO:00431231320.010
alcohol metabolic processGO:00060661140.010
cd8 positive alpha beta t cell activationGO:003603730.010
carboxylic acid transportGO:0046942630.010
cytokine mediated signaling pathwayGO:00192211090.010

PNPLA1 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:00146672950.035
sensory system diseaseDOID:00501552030.033
nervous system diseaseDOID:8634310.033
musculoskeletal system diseaseDOID:172230.023
eye and adnexa diseaseDOID:14921500.022
inherited metabolic disorderDOID:6552420.022
eye diseaseDOID:56141490.021
retinal diseaseDOID:56791180.019
connective tissue diseaseDOID:651090.015
bone diseaseDOID:0080001880.015
disease of cellular proliferationDOID:145661740.015
cancerDOID:1621670.014
immune system diseaseDOID:29141550.014
organ system cancerDOID:00506861640.014
retinal degenerationDOID:8466890.014
central nervous system diseaseDOID:3311860.013
cardiovascular system diseaseDOID:12871060.011
neurodegenerative diseaseDOID:12891020.011
acquired metabolic diseaseDOID:0060158580.010