Homo sapiens

6 known processes

PNPLA6

patatin-like phospholipase domain containing 6

(Aliases: NTEMND,SPG39,sws,NTE)

PNPLA6 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
ras protein signal transductionGO:0007265730.807
ribonucleotide catabolic processGO:00092614050.622
regulation of nucleotide metabolic processGO:00061402690.558
rab protein signal transductionGO:003248240.510
purine ribonucleotide catabolic processGO:00091544040.506
lipid metabolic processGO:00066293810.444
Fly
gtp metabolic processGO:00460392390.439
gtp catabolic processGO:00061842370.426
nucleoside triphosphate catabolic processGO:00091433940.420
purine ribonucleoside triphosphate catabolic processGO:00092073910.416
regulation of gtp catabolic processGO:00331241800.394
guanosine containing compound metabolic processGO:19010682440.376
regulation of ras protein signal transductionGO:00465781550.364
response to hormoneGO:00097251750.354
purine ribonucleoside metabolic processGO:00461284370.352
purine nucleoside triphosphate catabolic processGO:00091463920.351
actin cytoskeleton organizationGO:00300362070.346
glycosyl compound catabolic processGO:19016584130.345
positive regulation of purine nucleotide catabolic processGO:00331231850.338
purine nucleoside triphosphate metabolic processGO:00091444120.321
regulation of small gtpase mediated signal transductionGO:00510561560.320
purine nucleotide catabolic processGO:00061954050.320
positive regulation of rab gtpase activityGO:0032851390.316
positive regulation of gtp catabolic processGO:00331261660.312
actin filament based processGO:00300292240.306
ribonucleoside triphosphate metabolic processGO:00091994120.297
regulation of nucleotide catabolic processGO:00308112050.291
regulation of nucleoside metabolic processGO:00091182090.286
regulation of purine nucleotide catabolic processGO:00331212050.286
purine nucleoside catabolic processGO:00061523980.285
positive regulation of gtpase activityGO:00435471660.283
ribonucleoside catabolic processGO:00424544060.282
purine ribonucleoside triphosphate metabolic processGO:00092054110.277
nucleotide catabolic processGO:00091664080.269
positive regulation of ras gtpase activityGO:00323201170.267
guanosine containing compound catabolic processGO:19010692390.257
nucleoside catabolic processGO:00091644080.246
organophosphate catabolic processGO:00464344300.239
enzyme linked receptor protein signaling pathwayGO:00071673030.228
positive regulation of nucleotide catabolic processGO:00308131850.226
cellular ketone metabolic processGO:0042180800.221
positive regulation of nucleotide metabolic processGO:00459812300.215
vesicle mediated transportGO:00161923710.202
positive regulation of cellular catabolic processGO:00313312840.200
ribonucleoside triphosphate catabolic processGO:00092033910.197
nucleoside triphosphate metabolic processGO:00091414220.196
purine containing compound catabolic processGO:00725234110.195
regulation of rab gtpase activityGO:0032313390.194
small gtpase mediated signal transductionGO:0007264780.193
rho protein signal transductionGO:0007266260.191
regulation of gtpase activityGO:00430871800.168
positive regulation of nucleoside metabolic processGO:00459791860.154
positive regulation of hydrolase activityGO:00513453310.152
regulation of cellular ketone metabolic processGO:0010565500.137
cellular amine metabolic processGO:0044106410.136
Fly
membrane organizationGO:00610242920.135
Fly
regulation of ras gtpase activityGO:00323181280.131
amine metabolic processGO:0009308440.128
Fly
regulation of rho protein signal transductionGO:0035023790.118
purine ribonucleoside catabolic processGO:00461303980.104
positive regulation of catabolic processGO:00098963100.094
response to abiotic stimulusGO:00096283360.090
regulation of cellular component biogenesisGO:00440872810.088
cellular lipid metabolic processGO:00442553030.088
Fly
chemical homeostasisGO:00488783060.086
histone modificationGO:00165702510.082
regulation of purine nucleotide metabolic processGO:19005422640.081
locomotory behaviorGO:000762610.077
hemostasisGO:0007599760.073
lipid biosynthetic processGO:00086101770.071
endomembrane system organizationGO:00102561960.070
regulation of body fluid levelsGO:0050878990.067
cell developmentGO:00484683280.067
cell adhesionGO:00071553250.065
nervous system developmentGO:00073992930.063
cell projection organizationGO:00300302520.061
regulation of anatomical structure morphogenesisGO:00226032860.059
determination of adult lifespanGO:000834020.059
negative regulation of phosphate metabolic processGO:00459362670.058
cellular amino acid metabolic processGO:00065201160.058
protein localization to organelleGO:00333652800.057
single organism cellular localizationGO:19025803320.057
response to other organismGO:00517072610.054
nucleoside phosphate catabolic processGO:19012924120.054
positive regulation of purine nucleotide metabolic processGO:19005442270.054
positive regulation of protein phosphorylationGO:00019343130.053
negative regulation of cellular protein metabolic processGO:00322693530.052
regulation of protein kinase activityGO:00458592890.051
positive regulation of cellular amine metabolic processGO:003324070.050
protein localization to membraneGO:00726571600.049
cellular response to endogenous stimulusGO:00714953360.048
regulation of kinase activityGO:00435493140.047
multicellular organismal agingGO:001025930.047
glycerolipid metabolic processGO:00464861070.047
Fly
system processGO:00030083490.046
Fly
negative regulation of transportGO:00510511760.046
regulation of cell differentiationGO:00455953930.045
protein targetingGO:00066051870.045
actin filament organizationGO:00070151280.045
segmentationGO:003528240.045
defense responseGO:00069523150.044
maintenance of locationGO:00512351120.044
regulation of cellular component movementGO:00512703340.043
cytoplasmic transportGO:00164823790.043
cell substrate adhesionGO:00315891320.043
chromatin organizationGO:00063253510.042
transmembrane transportGO:00550853990.041
cellular homeostasisGO:00197251960.040
organophosphate biosynthetic processGO:00904071630.040
regulation of locomotionGO:00400123290.040
positive regulation of cellular component organizationGO:00511303760.039
regulation of neuron differentiationGO:0045664700.039
cellular component morphogenesisGO:00329893140.039
regulation of rab protein signal transductionGO:0032483390.039
cellular macromolecule catabolic processGO:00442653800.039
covalent chromatin modificationGO:00165692540.039
neuromuscular junction developmentGO:000752830.038
inorganic ion transmembrane transportGO:00986602310.038
regulation of transferase activityGO:00513383550.038
organelle assemblyGO:00709251760.038
response to biotic stimulusGO:00096072760.037
negative regulation of phosphorus metabolic processGO:00105632670.037
cellular response to external stimulusGO:00714961110.037
lipid modificationGO:0030258840.037
cell morphogenesisGO:00009022960.037
glycerophospholipid metabolic processGO:0006650840.037
Fly
regulation of response to external stimulusGO:00321012220.036
positive regulation of transportGO:00510503360.036
secretion by cellGO:00329402260.036
response to oxygen containing compoundGO:19017003690.036
mapk cascadeGO:00001652880.036
response to extracellular stimulusGO:0009991850.035
positive regulation of cellular amino acid metabolic processGO:004576430.035
signal transduction by phosphorylationGO:00230142970.035
regulation of cellular amine metabolic processGO:0033238110.035
inorganic cation transmembrane transportGO:00986621940.033
biological adhesionGO:00226103310.033
nitrogen compound transportGO:00717051910.033
alcohol metabolic processGO:00060661140.032
Fly
negative regulation of catalytic activityGO:00430863350.032
negative regulation of cellular component organizationGO:00511292350.032
monocarboxylic acid biosynthetic processGO:0072330670.031
endosomal transportGO:00161971290.031
cell matrix adhesionGO:0007160850.031
positive regulation of rho gtpase activityGO:0032321560.031
ion homeostasisGO:00508012300.030
ameboidal type cell migrationGO:00016671350.030
proteasomal protein catabolic processGO:00104981760.030
cell junction assemblyGO:0034329670.030
regulation of proteolysisGO:00301622930.029
single organism membrane organizationGO:00448022680.029
ruffle organizationGO:0031529180.029
cellular cation homeostasisGO:00300031630.029
peptidyl tyrosine phosphorylationGO:00181081700.029
regulation of mapk cascadeGO:00434082620.028
regulation of cellular response to stressGO:00801352440.028
nucleoside phosphate biosynthetic processGO:19012931090.028
sex determinationGO:000753030.028
protein processingGO:00164852260.028
anion transportGO:00068201610.028
chromatin modificationGO:00165682980.028
vacuole organizationGO:0007033440.028
regulation of cell projection organizationGO:00313441070.027
cellular response to hormone stimulusGO:00328701250.027
epithelium developmentGO:00604292270.027
microtubule cytoskeleton organizationGO:00002261760.027
immune effector processGO:00022521590.027
cellular response to peptide hormone stimulusGO:0071375560.026
amide transportGO:0042886760.026
post embryonic developmentGO:000979120.026
cellular protein catabolic processGO:00442572610.026
homotypic cell cell adhesionGO:0034109470.026
protein localization to plasma membraneGO:0072659930.025
cell junction organizationGO:0034330790.025
negative regulation of multicellular organismal processGO:00512413170.025
regulation of protein localizationGO:00328802960.024
negative regulation of protein kinase activityGO:0006469980.024
establishment of protein localization to membraneGO:00901501210.024
autophagyGO:0006914880.024
vesicle organizationGO:0016050620.024
cellular response to extracellular stimulusGO:0031668720.024
cell chemotaxisGO:00603261120.024
cytokine productionGO:00018162470.023
cellular chemical homeostasisGO:00550821800.023
regulation of nervous system developmentGO:0051960880.023
negative regulation of phosphorylationGO:00423261740.023
negative regulation of protein metabolic processGO:00512483910.023
cellular response to transforming growth factor beta stimulusGO:0071560940.023
neurological system processGO:00508771630.022
Fly
regulation of cellular amino acid metabolic processGO:000652160.022
peptidyl threonine modificationGO:0018210450.022
secretionGO:00469032540.022
receptor metabolic processGO:0043112810.022
response to organonitrogen compoundGO:00102431560.022
embryo developmentGO:00097901230.022
response to nitrogen compoundGO:19016981840.022
blood coagulationGO:0007596760.022
growthGO:00400072020.022
purine nucleoside monophosphate catabolic processGO:00091281580.022
protein catabolic processGO:00301633250.022
compound eye developmentGO:004874910.021
single organism cell adhesionGO:00986021790.021
regulation of secretion by cellGO:19035301770.021
mitotic cell cycleGO:00002783260.021
negative regulation of protein phosphorylationGO:00019331400.021
cellular response to starvationGO:0009267580.021
female gamete generationGO:000729220.020
positive regulation of kinase activityGO:00336742040.020
ruffle assemblyGO:0097178100.020
protein targeting to nucleusGO:00447441040.020
regulation of dephosphorylationGO:0035303960.020
regulation of cell developmentGO:00602841610.020
cation homeostasisGO:00550801890.020
positive regulation of phosphorylationGO:00423273940.020
modification dependent macromolecule catabolic processGO:00436322120.020
nucleus localizationGO:005164710.020
nucleoside monophosphate metabolic processGO:00091231910.020
plasma membrane organizationGO:00070091150.020
cell morphogenesis involved in differentiationGO:00009041440.020
regulation of cell motilityGO:20001452990.020
regulation of immune responseGO:00507762010.020
protein import into nucleusGO:00066061040.020
cellular ion homeostasisGO:00068731680.020
pattern specification processGO:0007389430.020
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.019
protein autophosphorylationGO:00467771230.019
blastoderm segmentationGO:000735020.019
neuron projection developmentGO:00311751060.019
cell migration involved in gastrulationGO:004207410.019
response to peptideGO:1901652650.019
mitotic cell cycle phase transitionGO:00447721620.019
epithelial cell migrationGO:00106311190.019
endocytosisGO:00068971590.019
cellular response to oxygen containing compoundGO:19017012760.018
activation of protein kinase activityGO:0032147900.018
negative regulation of apoptotic processGO:00430663160.018
cell activationGO:00017752130.018
negative regulation of protein modification processGO:00314002000.018
regulation of establishment of protein localizationGO:00702012420.018
cation transportGO:00068123310.018
response to external biotic stimulusGO:00432072610.018
ribonucleoside monophosphate metabolic processGO:00091611870.018
dephosphorylationGO:00163112090.018
peptidyl threonine phosphorylationGO:0018107410.018
positive regulation of cellular component movementGO:00512721810.018
establishment of protein localization to organelleGO:00725941720.018
rhythmic behaviorGO:000762220.017
response to woundingGO:00096111680.017
regulation of lipid metabolic processGO:0019216960.017
neurogenesisGO:00220081690.017
positive regulation of locomotionGO:00400171860.017
regulation of protein complex assemblyGO:00432541470.017
positive regulation of mapk cascadeGO:00434101900.017
regulation of cell migrationGO:00303342890.017
negative regulation of intracellular signal transductionGO:19025321830.017
positive regulation of transferase activityGO:00513472270.017
protein secretionGO:0009306980.016
focal adhesion assemblyGO:0048041300.016
interleukin 12 mediated signaling pathwayGO:003572230.016
internal protein amino acid acetylationGO:00064751010.016
regulation of growthGO:00400081650.016
positive regulation of cell divisionGO:0051781590.016
regulation of secretionGO:00510461940.016
response to peptide hormoneGO:0043434610.016
neuron differentiationGO:00301821380.016
peptidyl serine modificationGO:00182091060.016
negative regulation of transferase activityGO:00513481240.016
phosphatidic acid biosynthetic processGO:000665440.016
organonitrogen compound biosynthetic processGO:19015662000.016
cellular response to nutrient levelsGO:0031669690.016
memoryGO:000761330.016
protein dephosphorylationGO:0006470810.015
monocarboxylic acid metabolic processGO:00327871850.015
regulation of cell activationGO:00508651250.015
lipid localizationGO:00108761060.015
negative regulation of hydrolase activityGO:00513461820.015
intracellular protein transportGO:00068862700.015
positive regulation of developmental processGO:00510943140.015
peptide transportGO:0015833740.015
neuron developmentGO:00486661130.015
peptidyl serine phosphorylationGO:00181051010.015
purine ribonucleoside monophosphate metabolic processGO:00091671860.015
protein localization to nucleusGO:00345041360.015
protein maturationGO:00516042330.015
regionalizationGO:0003002290.015
negative regulation of developmental processGO:00510932470.015
regulation of ion transportGO:00432691890.015
regulation of cell cycleGO:00517263930.015
positive regulation of cell proliferationGO:00082843010.015
regulation of plasma lipoprotein particle levelsGO:0097006320.015
negative regulation of cell deathGO:00605483450.015
chemotaxisGO:00069351570.015
negative regulation of protein processingGO:00109551420.015
negative regulation of protein maturationGO:19033181420.014
head developmentGO:00603221080.014
golgi organizationGO:0007030380.014
peptidyl lysine modificationGO:00182051440.014
cellular response to growth factor stimulusGO:00713631970.014
positive regulation of secretionGO:00510471160.014
spermatid differentiationGO:004851540.014
circadian behaviorGO:004851220.014
regulation of cell adhesionGO:00301551660.014
brain developmentGO:0007420970.014
negative regulation of organelle organizationGO:00106391260.014
proteolysis involved in cellular protein catabolic processGO:00516032440.014
single organismal cell cell adhesionGO:00163371480.014
phospholipid biosynthetic processGO:0008654440.014
adherens junction organizationGO:0034332360.014
purine nucleoside monophosphate metabolic processGO:00091261860.014
spermatid developmentGO:000728640.014
positive regulation of protein kinase activityGO:00458601900.014
fatty acid biosynthetic processGO:0006633460.013
regulation of cell morphogenesisGO:00226041530.013
regulation of intracellular transportGO:00323861950.013
cell cell junction organizationGO:0045216690.013
positive regulation of cell developmentGO:0010720920.013
cation transmembrane transportGO:00986552380.013
steroid metabolic processGO:0008202940.013
anatomical structure formation involved in morphogenesisGO:00486462840.013
Mouse
taxisGO:00423301570.013
small molecule biosynthetic processGO:00442831570.013
cell substrate adherens junction assemblyGO:0007045300.013
cell part morphogenesisGO:00329901370.013
nucleocytoplasmic transportGO:00069131760.013
cytokine mediated signaling pathwayGO:00192211090.013
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781250.013
wound healingGO:00420601150.013
macroautophagyGO:0016236390.013
tissue migrationGO:00901301190.013
response to growth factorGO:00708482050.013
negative regulation of kinase activityGO:00336731060.013
cyclic nucleotide biosynthetic processGO:0009190610.013
nuclear transportGO:00511691790.013
response to fungusGO:000962040.013
phospholipid metabolic processGO:0006644990.012
Fly
regulation of proteolysis involved in cellular protein catabolic processGO:1903050910.012
innate immune responseGO:00450871780.012
stem cell divisionGO:001714520.012
atp catabolic processGO:00062001570.012
ribonucleotide biosynthetic processGO:0009260810.012
regulation of response to woundingGO:19030341010.012
hormone secretionGO:0046879650.012
response to bacteriumGO:00096171440.012
circulatory system developmentGO:00723592620.012
Mouse
neuroblast proliferationGO:000740540.012
positive regulation of neuron differentiationGO:0045666400.012
ribose phosphate biosynthetic processGO:0046390820.012
metal ion transportGO:00300012720.012
positive regulation of cytoskeleton organizationGO:0051495830.012
atp metabolic processGO:00460341760.012
regulation of chromatin modificationGO:1903308510.012
positive regulation of cell differentiationGO:00455972110.012
protein acylationGO:00435431380.012
regulation of protein processingGO:00706131500.012
regulation of neuron projection developmentGO:0010975570.012
response to cytokineGO:00340972320.012
regulation of cell cycle processGO:00105642660.012
platelet aggregationGO:0070527320.011
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.011
actin cytoskeleton reorganizationGO:0031532370.011
positive regulation of cytokinesisGO:0032467290.011
microtubule based processGO:00070172100.011
cellular response to tumor necrosis factorGO:0071356630.011
regulation of dna metabolic processGO:00510521530.011
ectodermal placode developmentGO:007169610.011
epithelial cell differentiationGO:00308551410.011
maintenance of location in cellGO:0051651620.011
positive regulation of cell projection organizationGO:0031346640.011
cellular response to peptideGO:1901653590.011
regulation of cell divisionGO:00513021160.011
cell cycle arrestGO:0007050710.011
positive regulation of cellular component biogenesisGO:00440891580.011
regulation of protein maturationGO:19033171500.011
receptor mediated endocytosisGO:0006898840.011
adherens junction assemblyGO:0034333340.011
response to hypoxiaGO:0001666960.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092900.011
positive regulation of response to external stimulusGO:0032103880.011
response to decreased oxygen levelsGO:0036293960.011
regulation of neurogenesisGO:0050767820.011
camp biosynthetic processGO:0006171470.011
immune system developmentGO:00025201950.011
cellular response to organonitrogen compoundGO:00714171240.011
regulation of epithelial cell proliferationGO:00506781130.011
positive regulation of cell motilityGO:20001471770.011
cell projection morphogenesisGO:00488581290.011
response to inorganic substanceGO:00100351270.011
negative regulation of cellular amino acid metabolic processGO:004576320.011
convergent extensionGO:006002610.011
adult locomotory behaviorGO:000834410.011
regulation of phosphatase activityGO:0010921810.010
regulation of map kinase activityGO:00434051080.010
regulation of defense responseGO:00313471540.010
monovalent inorganic cation transportGO:00156721280.010
modification dependent protein catabolic processGO:00199412090.010
inorganic anion transportGO:0015698600.010
internal peptidyl lysine acetylationGO:0018393970.010
regulation of sequence specific dna binding transcription factor activityGO:00510902110.010
epithelium migrationGO:00901321190.010
cellular response to nitrogen compoundGO:19016991440.010
neural tube formationGO:000184130.010
cellular response to interleukin 12GO:007134930.010
generation of neuronsGO:00486991520.010
g protein coupled receptor signaling pathwayGO:00071862070.010

PNPLA6 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
central nervous system diseaseDOID:3311860.025
nervous system diseaseDOID:8634310.025
neurodegenerative diseaseDOID:12891020.015
musculoskeletal system diseaseDOID:172230.013
osteosclerosisDOID:4254160.013
connective tissue diseaseDOID:651090.013
bone remodeling diseaseDOID:0080005260.013
osteopetrosisDOID:1353390.013
bone diseaseDOID:0080001880.013
immune system diseaseDOID:29141550.010
paraplegiaDOID:607190.002
hereditary spastic paraplegiaDOID:2476190.002