Homo sapiens

98 known processes

PNPLA8

patatin-like phospholipase domain containing 8

(Aliases: IPLA2G,IPLA2-2,IPLA2(GAMMA))

PNPLA8 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
modification dependent protein catabolic processGO:00199412090.171
cellular protein catabolic processGO:00442572610.121
protein ubiquitinationGO:00165673140.109
post embryonic developmentGO:000979120.101
modification dependent macromolecule catabolic processGO:00436322120.082
nucleoside phosphate catabolic processGO:19012924120.081
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.079
cellular macromolecule catabolic processGO:00442653800.077
oogenesisGO:004847720.076
gtp metabolic processGO:00460392390.074
organophosphate catabolic processGO:00464344300.071
proteasomal protein catabolic processGO:00104981760.069
posttranscriptional regulation of gene expressionGO:00106082130.068
proteolysis involved in cellular protein catabolic processGO:00516032440.065
ubiquitin dependent protein catabolic processGO:00065112060.064
protein catabolic processGO:00301633250.064
purine containing compound catabolic processGO:00725234110.063
lipid metabolic processGO:00066293810.061
amine metabolic processGO:0009308440.058
cytoplasmic transportGO:00164823790.057
intracellular protein transportGO:00068862700.052
positive regulation of nucleoside metabolic processGO:00459791860.051
response to woundingGO:00096111680.051
ribonucleoside triphosphate metabolic processGO:00091994120.051
protein localization to organelleGO:00333652800.049
female gamete generationGO:000729220.047
purine ribonucleoside metabolic processGO:00461284370.047
regulation of cellular response to stressGO:00801352440.046
purine ribonucleoside catabolic processGO:00461303980.046
positive regulation of cellular catabolic processGO:00313312840.045
nucleoside triphosphate metabolic processGO:00091414220.042
cellular lipid metabolic processGO:00442553030.042
cellular amine metabolic processGO:0044106410.039
ras protein signal transductionGO:0007265730.038
positive regulation of catabolic processGO:00098963100.038
positive regulation of gtp catabolic processGO:00331261660.038
positive regulation of gtpase activityGO:00435471660.038
regulation of gtpase activityGO:00430871800.037
chondroitin sulfate proteoglycan biosynthetic processGO:0050650100.037
single organism cellular localizationGO:19025803320.037
ribonucleoside catabolic processGO:00424544060.037
purine nucleoside catabolic processGO:00061523980.036
regulation of cellular amino acid metabolic processGO:000652160.036
positive regulation of transportGO:00510503360.035
purine ribonucleotide catabolic processGO:00091544040.035
negative regulation of protein metabolic processGO:00512483910.033
glycoprotein metabolic processGO:00091001100.033
ribonucleoside triphosphate catabolic processGO:00092033910.033
regulation of cytoplasmic transportGO:19036491490.032
positive regulation of cellular amine metabolic processGO:003324070.032
unidimensional cell growthGO:000982610.031
cellular component morphogenesisGO:00329893140.031
cell morphogenesisGO:00009022960.030
purine nucleoside triphosphate metabolic processGO:00091444120.030
regulation of nucleoside metabolic processGO:00091182090.030
negative regulation of phosphate metabolic processGO:00459362670.029
purine nucleotide catabolic processGO:00061954050.029
regulation of nucleotide metabolic processGO:00061402690.029
response to abiotic stimulusGO:00096283360.029
wnt signaling pathwayGO:00160551560.028
positive regulation of purine nucleotide metabolic processGO:19005442270.028
regulation of intracellular transportGO:00323861950.028
regulation of nucleotide catabolic processGO:00308112050.028
carbohydrate derivative biosynthetic processGO:19011372070.028
negative regulation of cellular protein metabolic processGO:00322693530.028
guanosine containing compound catabolic processGO:19010692390.027
purine nucleoside triphosphate catabolic processGO:00091463920.027
cellular ketone metabolic processGO:0042180800.027
mechanosensory behaviorGO:000763840.026
regulation of protein localizationGO:00328802960.026
purine ribonucleoside triphosphate metabolic processGO:00092054110.026
protein stabilizationGO:0050821640.026
protein modification by small protein conjugationGO:00324463420.026
positive regulation of hydrolase activityGO:00513453310.025
regulation of gtp catabolic processGO:00331241800.025
gtp catabolic processGO:00061842370.025
nucleoside catabolic processGO:00091644080.025
glycosyl compound catabolic processGO:19016584130.025
regulation of response to external stimulusGO:00321012220.024
regulation of intracellular protein transportGO:00331571230.023
regulation of proteolysisGO:00301622930.023
positive regulation of nucleotide catabolic processGO:00308131850.023
regulation of anatomical structure morphogenesisGO:00226032860.023
positive regulation of cellular amino acid metabolic processGO:004576430.023
lipid biosynthetic processGO:00086101770.022
cellular amino acid metabolic processGO:00065201160.022
positive regulation of purine nucleotide catabolic processGO:00331231850.022
negative regulation of cellular component organizationGO:00511292350.022
guanosine containing compound metabolic processGO:19010682440.022
chemical homeostasisGO:00488783060.021
actin mediated cell contractionGO:0070252120.021
negative regulation of phosphorus metabolic processGO:00105632670.021
nucleotide catabolic processGO:00091664080.021
regulation of protein kinase activityGO:00458592890.021
regulation of cellular ketone metabolic processGO:0010565500.021
cell growthGO:00160491600.020
regulation of protein stabilityGO:0031647870.020
multicellular organismal agingGO:001025930.020
adenylate cyclase modulating g protein coupled receptor signaling pathwayGO:0007188430.020
regulation of transferase activityGO:00513383550.020
positive regulation of cell deathGO:00109422630.019
determination of adult lifespanGO:000834020.019
positive regulation of exocytosisGO:0045921350.019
small gtpase mediated signal transductionGO:0007264780.019
regulation of cell cycle processGO:00105642660.019
regulation of cell cycleGO:00517263930.019
regulation of cellular amine metabolic processGO:0033238110.019
regulation of apoptotic signaling pathwayGO:20012331750.019
organonitrogen compound biosynthetic processGO:19015662000.018
purine ribonucleoside triphosphate catabolic processGO:00092073910.018
endomembrane system organizationGO:00102561960.018
positive regulation of nucleotide metabolic processGO:00459812300.018
cellular cation homeostasisGO:00300031630.018
dephosphorylationGO:00163112090.018
secretion by cellGO:00329402260.018
protein polyubiquitinationGO:00002091100.018
defense responseGO:00069523150.018
cilium morphogenesisGO:0060271750.017
glycerolipid metabolic processGO:00464861070.017
chromatin modificationGO:00165682980.017
positive regulation of cellular component organizationGO:00511303760.017
regulation of kinase activityGO:00435493140.017
regulation of vesicle mediated transportGO:00606271300.017
positive regulation of secretion by cellGO:19035321080.017
vesicle mediated transportGO:00161923710.016
negative regulation of programmed cell deathGO:00430693210.016
negative regulation of apoptotic processGO:00430663160.016
negative regulation of phosphorylationGO:00423261740.016
regulation of purine nucleotide catabolic processGO:00331212050.016
regulation of tor signalingGO:0032006300.016
monovalent inorganic cation transportGO:00156721280.015
response to oxidative stressGO:00069791210.015
chromatin organizationGO:00063253510.015
cation transportGO:00068123310.015
nitrogen compound transportGO:00717051910.015
mitochondrion organizationGO:00070051560.015
protein localization to nucleusGO:00345041360.015
metal ion transportGO:00300012720.015
fatty acid metabolic processGO:00066311150.015
regulation of establishment of protein localizationGO:00702012420.015
positive regulation of secretionGO:00510471160.015
regulation of protein transportGO:00512232130.015
ribonucleotide catabolic processGO:00092614050.014
positive regulation of programmed cell deathGO:00430682490.014
somatic muscle developmentGO:000752510.014
protein import into nucleusGO:00066061040.014
cell projection organizationGO:00300302520.014
establishment of protein localization to organelleGO:00725941720.014
single organism nuclear importGO:19025931040.014
cellular macromolecular complex assemblyGO:00346223240.014
positive regulation of phosphorylationGO:00423273940.014
regulation of secretionGO:00510461940.013
regulation of nucleocytoplasmic transportGO:0046822980.013
positive regulation of cell proliferationGO:00082843010.013
positive regulation of apoptotic processGO:00430652460.013
positive regulation of cytosolic calcium ion concentrationGO:0007204820.013
regulation of cellular component biogenesisGO:00440872810.013
immune responseGO:00069553070.013
neurotransmitter secretionGO:000726940.013
er associated ubiquitin dependent protein catabolic processGO:0030433310.013
regulation of cell projection organizationGO:00313441070.013
cilium organizationGO:0044782680.013
post golgi vesicle mediated transportGO:0006892360.013
secretionGO:00469032540.013
regulation of gene expression epigeneticGO:0040029730.013
mitotic cell cycleGO:00002783260.013
rho protein signal transductionGO:0007266260.013
cellular chemical homeostasisGO:00550821800.013
regulation of cytoskeleton organizationGO:00514931770.013
regulation of dna metabolic processGO:00510521530.013
negative regulation of cell cycleGO:00457861930.013
golgi vesicle transportGO:0048193800.012
regulation of immune responseGO:00507762010.012
regulation of neurotransmitter secretionGO:004692830.012
negative regulation of protein phosphorylationGO:00019331400.012
apoptotic signaling pathwayGO:00971902680.012
vacuolar transportGO:0007034340.012
histone modificationGO:00165702510.012
plasma membrane organizationGO:00070091150.012
negative regulation of cellular amino acid metabolic processGO:004576320.012
lipid transportGO:0006869900.012
g protein coupled receptor signaling pathwayGO:00071862070.012
nuclear transportGO:00511691790.012
axon cargo transportGO:000808820.012
regulation of i kappab kinase nf kappab signalingGO:00431221620.012
negative regulation of axonogenesisGO:005077140.012
cilium assemblyGO:0042384630.012
negative regulation of protein modification processGO:00314002000.011
cellular ion homeostasisGO:00068731680.011
endosomal transportGO:00161971290.011
negative regulation of growthGO:0045926970.011
response to organic cyclic compoundGO:00140702040.011
mitotic cell cycle processGO:19030472860.011
response to oxygen containing compoundGO:19017003690.011
autophagyGO:0006914880.011
negative regulation of axon extensionGO:003051720.011
regulation of proteasomal protein catabolic processGO:0061136870.011
negative regulation of cell cycle processGO:00109481210.011
i kappab kinase nf kappab signalingGO:00072491660.011
regulation of cell morphogenesisGO:00226041530.011
rna interferenceGO:001624640.011
spermatid developmentGO:000728640.011
gastrulation with mouth forming secondGO:000170210.011
membrane lipid metabolic processGO:0006643530.011
negative regulation of catalytic activityGO:00430863350.011
cellular response to endogenous stimulusGO:00714953360.011
maintenance of locationGO:00512351120.011
covalent chromatin modificationGO:00165692540.011
negative regulation of transportGO:00510511760.011
nucleoside triphosphate catabolic processGO:00091433940.011
actin filament based processGO:00300292240.011
positive regulation of immune responseGO:00507781590.011
ion homeostasisGO:00508012300.011
protein importGO:00170381300.011
hindbrain developmentGO:003090230.010
regulation of protein catabolic processGO:00421761550.010
positive regulation of organelle organizationGO:00106381950.010
canonical wnt signaling pathwayGO:00600701160.010
cell cycle checkpointGO:00000751170.010
tissue regenerationGO:004224630.010
liposaccharide metabolic processGO:1903509270.010

PNPLA8 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:145661740.025
organ system cancerDOID:00506861640.019
cancerDOID:1621670.019
nervous system diseaseDOID:8634310.019
sensory system diseaseDOID:00501552030.019
disease of metabolismDOID:00146672950.012
central nervous system diseaseDOID:3311860.010
brain diseaseDOID:936730.010
retinal diseaseDOID:56791180.010
eye diseaseDOID:56141490.010
eye and adnexa diseaseDOID:14921500.010