Homo sapiens

130 known processes

SFPQ

splicing factor proline/glutamine-rich

(Aliases: PSF,POMP100)

SFPQ biological process predictions


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Biological processGO term IDProcess sizeProbabilityFunc Analog Org
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.978
rna splicingGO:00083801310.957
mrna metabolic processGO:00160711750.925
positive regulation of response to oxidative stressGO:190288470.921
positive regulation of oxidative stress induced intrinsic apoptotic signaling pathwayGO:190217740.896
regulation of intrinsic apoptotic signaling pathwayGO:2001242720.878
neuron intrinsic apoptotic signaling pathway in response to oxidative stressGO:003648070.871
Human
intrinsic apoptotic signaling pathwayGO:00971931270.828
regulation of cellular response to stressGO:00801352440.813
negative regulation of response to oxidative stressGO:1902883180.767
Human
positive regulation of intrinsic apoptotic signaling pathwayGO:2001244280.750
positive regulation of oxidative stress induced cell deathGO:190320950.736
regulation of meiotic cell cycleGO:005144540.716
negative regulation of oxidative stress induced cell deathGO:1903202170.705
Human
negative regulation of oxidative stress induced neuron intrinsic apoptotic signaling pathwayGO:190337750.693
Human
regulation of oxidative stress induced cell deathGO:1903201240.664
rna processingGO:00063962550.653
positive regulation of programmed cell deathGO:00430682490.614
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377890.590
positive regulation of apoptotic processGO:00430652460.552
alternative mrna splicing via spliceosomeGO:0000380270.539
regulation of mrna splicing via spliceosomeGO:0048024320.538
regulation of meiosisGO:004002030.531
positive regulation of apoptotic signaling pathwayGO:2001235700.501
regulation of mrna processingGO:0050684480.489
regulation of cellular response to oxidative stressGO:1900407260.485
multicellular organismal agingGO:001025930.456
regulation of circadian rhythmGO:0042752110.455
Mouse
mrna processingGO:00063971330.455
mitotic cell cycleGO:00002783260.444
regulation of alternative mrna splicing via spliceosomeGO:0000381220.411
organelle fissionGO:00482851490.408
mrna splicing via spliceosomeGO:0000398890.407
cell developmentGO:00484683280.397
Zebrafish
locomotory behaviorGO:000762610.386
rna interferenceGO:001624640.361
regulation of cellular component biogenesisGO:00440872810.348
blastoderm segmentationGO:000735020.346
regulation of apoptotic signaling pathwayGO:20012331750.337
visual perceptionGO:0007601270.328
Fly
negative regulation of oxidative stress induced neuron deathGO:190320470.318
Human
negative regulation of intrinsic apoptotic signaling pathwayGO:2001243400.310
Human
neuron death in response to oxidative stressGO:003647590.292
Human
positive regulation of cellular component organizationGO:00511303760.272
cell divisionGO:00513011680.267
chromatin assembly or disassemblyGO:0006333780.261
post embryonic developmentGO:000979120.258
Worm
intracellular receptor signaling pathwayGO:00305221040.257
dna packagingGO:0006323770.252
epithelium developmentGO:00604292270.237
posttranscriptional gene silencing by rnaGO:0035194250.229
negative regulation of cell deathGO:00605483450.212
Human
regulation of mrna stabilityGO:0043488230.203
sensory perception of light stimulusGO:0050953350.202
Fly
negative regulation of intracellular signal transductionGO:19025321830.181
Human
meiotic nuclear divisionGO:0007126100.179
nuclear divisionGO:00002801280.164
nuclear exportGO:0051168690.162
regulation of cell cycleGO:00517263930.157
cellular response to dna damage stimulusGO:00069743790.157
negative regulation of cellular protein metabolic processGO:00322693530.152
rna splicing via transesterification reactionsGO:0000375900.152
mitotic cell cycle processGO:19030472860.148
heart developmentGO:0007507950.147
viral processGO:00160321460.143
defense responseGO:00069523150.140
reproductionGO:0000003630.139
Worm Fly
sensory organ developmentGO:0007423520.137
secretionGO:00469032540.129
actin cytoskeleton organizationGO:00300362070.129
covalent chromatin modificationGO:00165692540.127
Mouse
oogenesisGO:004847720.125
chromatin silencing at rdnaGO:000018350.123
vesicle mediated transportGO:00161923710.123
regulation of oxidative stress induced neuron intrinsic apoptotic signaling pathwayGO:190337670.122
Human
response to oxidative stressGO:00069791210.121
determination of adult lifespanGO:000834020.116
rna stabilizationGO:0043489180.112
negative regulation of cellular response to oxidative stressGO:1900408180.112
Human
lymphocyte mediated immunityGO:0002449480.110
negative regulation of protein metabolic processGO:00512483910.110
oocyte differentiationGO:000999420.110
cell type specific apoptotic processGO:00972851250.108
Human
cellular response to oxidative stressGO:0034599850.107
neuron apoptotic processGO:0051402390.104
Human
cardiovascular system developmentGO:00723582620.101
circadian rhythmGO:0007623210.101
Mouse
anterior posterior axis specificationGO:000994820.096
rhythmic processGO:0048511310.096
Mouse
regulation of mitotic cell cycle phase transitionGO:19019901180.096
interspecies interaction between organismsGO:00444191560.095
nucleosome assemblyGO:0006334500.093
posttranscriptional regulation of gene expressionGO:00106082130.092
modification of morphology or physiology of other organismGO:0035821430.091
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781250.090
adult locomotory behaviorGO:000834410.089
cellular amine metabolic processGO:0044106410.089
actin filament based processGO:00300292240.085
regulation of response to oxidative stressGO:1902882260.084
regulation of cellular amino acid metabolic processGO:000652160.084
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathwayGO:1902176100.084
Human
positive regulation of developmental processGO:00510943140.084
dna recombinationGO:0006310770.081
embryo developmentGO:00097901230.078
regulation of nervous system developmentGO:0051960880.077
Zebrafish
positive regulation of cell deathGO:00109422630.077
regulation of gene expression epigeneticGO:0040029730.077
negative regulation of apoptotic signaling pathwayGO:2001234970.076
Human
regulation of cell cycle phase transitionGO:19019871260.072
apoptotic signaling pathwayGO:00971902680.071
regulation of cell cycle processGO:00105642660.069
hemopoiesisGO:00300971800.068
neuromuscular junction developmentGO:000752830.067
positive regulation of cellular component biogenesisGO:00440891580.067
regulation of neuron apoptotic processGO:0043523350.065
Human
negative regulation of epidermal cell differentiationGO:004560540.064
establishment or maintenance of cytoskeleton polarityGO:003095230.064
regulation of mrna metabolic processGO:1903311530.062
regulation of leukocyte activationGO:00026941150.061
regulation of epithelial cell proliferationGO:00506781130.061
cellular response to transforming growth factor beta stimulusGO:0071560940.061
reproductive processGO:00224141060.059
Fly
regulation of nuclear divisionGO:0051783650.059
organ morphogenesisGO:00098871470.058
negative regulation of programmed cell deathGO:00430693210.057
Human
mrna stabilizationGO:0048255180.056
cell cycle phase transitionGO:00447701730.055
negative regulation of apoptotic processGO:00430663160.054
Human
retina development in camera type eyeGO:0060041150.053
positive regulation of nervous system developmentGO:0051962540.052
spermatid developmentGO:000728640.052
cellular component morphogenesisGO:00329893140.051
dna conformation changeGO:00711031130.051
sensory perceptionGO:00076001030.050
Fly
establishment or maintenance of microtubule cytoskeleton polarityGO:003095120.050
cellular amino acid metabolic processGO:00065201160.050
regulation of cellular amine metabolic processGO:0033238110.050
histone modificationGO:00165702510.049
Mouse
cell activationGO:00017752130.049
proteasomal protein catabolic processGO:00104981760.048
negative regulation of multi organism processGO:0043901920.048
microtubule based processGO:00070172100.046
negative regulation of rna splicingGO:0033119150.044
positive regulation of mitotic cell cycleGO:0045931600.043
cell death in response to oxidative stressGO:0036473290.043
cytoplasmic transportGO:00164823790.043
regulation of neuron deathGO:1901214560.042
Human
chromosome condensationGO:0030261150.042
regulation of protein stabilityGO:0031647870.041
tripartite regional subdivisionGO:000735120.041
regulation of dna recombinationGO:0000018230.041
striated muscle cell differentiationGO:0051146430.040
positive regulation of organelle organizationGO:00106381950.039
negative regulation of neuron deathGO:1901215320.039
Human
adult behaviorGO:0030534180.039
protein stabilizationGO:0050821640.039
maintenance of locationGO:00512351120.038
segmentationGO:003528240.037
positive regulation of chromatin assembly or disassemblyGO:004579920.036
protein methylationGO:0006479740.036
chordate embryonic developmentGO:0043009340.036
spermatid differentiationGO:004851540.035
regulation of protein complex assemblyGO:00432541470.035
growthGO:00400072020.035
Worm
negative regulation of chromatin silencingGO:003193640.035
determination of bilateral symmetryGO:0009855150.035
amine metabolic processGO:0009308440.034
nucleoside triphosphate catabolic processGO:00091433940.034
negative regulation of organelle organizationGO:00106391260.034
ribonucleoprotein complex export from nucleusGO:007142640.034
multi organism cellular processGO:00447641560.034
response to organic cyclic compoundGO:00140702040.034
eye developmentGO:0001654420.034
posttranscriptional gene silencingGO:0016441250.033
circulatory system developmentGO:00723592620.032
muscle system processGO:0003012810.032
negative regulation of cellular amine metabolic processGO:003323930.032
cytokinesisGO:0000910960.032
macromolecule methylationGO:0043414970.031
regulation of cellular component movementGO:00512703340.031
response to transforming growth factor betaGO:0071559940.031
small molecule biosynthetic processGO:00442831570.030
leukocyte activationGO:00453211640.030
ossificationGO:00015031210.030
regulation of g1 s transition of mitotic cell cycleGO:2000045400.030
atrial septum primum morphogenesisGO:000328910.030
cellular chemical homeostasisGO:00550821800.030
circadian regulation of translationGO:009716710.030
regulation of cell differentiationGO:00455953930.029
Zebrafish
immune system developmentGO:00025201950.029
negative regulation of neuron apoptotic processGO:0043524230.029
Human
stem cell maintenanceGO:0019827190.029
regulation of growthGO:00400081650.028
photoreceptor cell differentiationGO:004653020.028
single organism membrane organizationGO:00448022680.028
regulation of cell cycle g1 s phase transitionGO:1902806420.028
viral transcriptionGO:0019083350.028
negative regulation of dna metabolic processGO:0051053570.027
purine ribonucleotide catabolic processGO:00091544040.027
immune effector processGO:00022521590.027
nucleoside catabolic processGO:00091644080.027
positive regulation of translationGO:0045727350.027
purine ribonucleoside triphosphate metabolic processGO:00092054110.027
negative regulation of cellular component organizationGO:00511292350.027
Zebrafish
leukocyte differentiationGO:0002521980.027
hair cycleGO:0042633280.027
positive regulation of cell activationGO:0050867810.027
regulation of cell activationGO:00508651250.027
regulation of mitotic cell cycleGO:00073461890.026
cellular response to organic cyclic compoundGO:00714071270.026
regulation of canonical wnt signaling pathwayGO:0060828880.026
muscle structure developmentGO:0061061980.025
hematopoietic progenitor cell differentiationGO:0002244380.025
central nervous system developmentGO:00074171230.025
Zebrafish
generation of neuronsGO:00486991520.024
Zebrafish
dna templated transcription initiationGO:0006352350.024
nucleosome positioningGO:001658430.024
negative regulation of cell cycle processGO:00109481210.024
chromatin remodelingGO:0006338550.024
chromatin modificationGO:00165682980.023
Mouse
alcohol metabolic processGO:00060661140.023
androgen receptor signaling pathwayGO:0030521340.023
lymphocyte differentiationGO:0030098350.023
digestive tract morphogenesisGO:0048546560.023
regulation of oxidative stress induced intrinsic apoptotic signaling pathwayGO:1902175160.023
regulation of rna stabilityGO:0043487230.023
negative regulation of cellular response to growth factor stimulusGO:0090288410.023
anterior posterior axis specification embryoGO:000859520.023
nucleotide catabolic processGO:00091664080.022
transforming growth factor beta receptor signaling pathwayGO:0007179760.022
regulation of chromatin modificationGO:1903308510.022
membrane organizationGO:00610242920.022
mesenchymal cell differentiationGO:0048762520.022
negative regulation of locomotionGO:00400131180.022
ras protein signal transductionGO:0007265730.021
cellular ion homeostasisGO:00068731680.021
regulation of proteolysisGO:00301622930.021
regulation of response to dna damage stimulusGO:2001020940.020
negative regulation of cellular amino acid metabolic processGO:004576320.020
modulation by host of viral transcriptionGO:0043921200.020
regulation of cell divisionGO:00513021160.020
negative regulation of catalytic activityGO:00430863350.020
regulation of anatomical structure morphogenesisGO:00226032860.020
pattern specification processGO:0007389430.019
muscle tissue developmentGO:0060537620.019
negative regulation of protein modification processGO:00314002000.019
ventricular septum morphogenesisGO:006041230.019
sexual reproductionGO:0019953370.019
Fly
positive regulation of immune system processGO:00026842830.019
regulation of chromatin organizationGO:1902275560.019
regulation of dna metabolic processGO:00510521530.018
nucleosome organizationGO:0034728660.018
positive regulation of lymphocyte activationGO:0051251730.018
positive regulation of multi organism processGO:0043902560.018
protein catabolic processGO:00301633250.018
regulation of cell morphogenesisGO:00226041530.018
regulation of lymphocyte activationGO:00512491030.018
negative regulation of gene expression epigeneticGO:0045814190.018
epithelial cell differentiationGO:00308551410.018
dna templated transcription terminationGO:000635330.018
positive regulation of cell differentiationGO:00455972110.018
rna transportGO:0050658390.017
dephosphorylationGO:00163112090.017
nervous system developmentGO:00073992930.017
Zebrafish
regulation of establishment of protein localizationGO:00702012420.017
negative regulation of growthGO:0045926970.017
response to woundingGO:00096111680.017
Zebrafish
neurological system processGO:00508771630.017
Fly
cell growthGO:00160491600.016
sex determinationGO:000753030.016
molting cycleGO:0042303280.016
erythrocyte developmentGO:004882130.016
regulation of viral transcriptionGO:0046782340.016
muscle cell differentiationGO:0042692630.016
organelle assemblyGO:00709251760.016
single organism reproductive processGO:0044702980.016
myeloid cell differentiationGO:00300991170.016
cellular response to endogenous stimulusGO:00714953360.016
actomyosin structure organizationGO:0031032590.016
cellular ketone metabolic processGO:0042180800.015
negative regulation of cell motilityGO:20001461040.015
regulation of response to external stimulusGO:00321012220.015
Zebrafish
macromolecule deacylationGO:0098732410.015
Mouse
epidermis developmentGO:0008544590.015
nitrogen compound transportGO:00717051910.015
mitotic chromosome condensationGO:0007076110.015
behaviorGO:00076101120.015
Fly
positive regulation of dna metabolic processGO:0051054730.015
chromatin organizationGO:00063253510.015
Mouse
lipid localizationGO:00108761060.015
wnt signaling pathwayGO:00160551560.015
positive regulation of chromosome organizationGO:2001252410.015
positive regulation of epithelial cell proliferationGO:0050679650.014
system processGO:00030083490.014
Fly
gene silencing by mirnaGO:0035195230.014
snrna metabolic processGO:0016073150.014
regulation of wound healingGO:0061041560.014
dna repairGO:00062811980.014
female gamete generationGO:000729220.014
gene silencing by rnaGO:0031047260.014
stem cell differentiationGO:0048863930.014
response to nutrient levelsGO:0031667810.014
regulation of wnt signaling pathwayGO:00301111230.014
genitalia developmentGO:0048806100.014
positive regulation of immunoglobulin productionGO:000263940.014
response to abiotic stimulusGO:00096283360.014
organonitrogen compound biosynthetic processGO:19015662000.014
striated muscle cell developmentGO:0055002270.013
regulation of mapk cascadeGO:00434082620.013
neurogenesisGO:00220081690.013
Zebrafish
specification of symmetryGO:0009799160.013
regulation of rna splicingGO:0043484620.013
negative regulation of axonogenesisGO:005077140.013
cellular cation homeostasisGO:00300031630.013
protein dna complex subunit organizationGO:0071824800.013
regulation of innate immune responseGO:0045088970.013
ribosomal large subunit export from nucleusGO:000005530.013
intracellular protein transportGO:00068862700.013
protein ubiquitinationGO:00165673140.013
negative regulation of cell growthGO:0030308830.013
embryo development ending in birth or egg hatchingGO:0009792340.013
regulation of neuron differentiationGO:0045664700.013
Zebrafish
heart loopingGO:000194770.013
regulation of dna templated transcription initiationGO:200014290.012
somatic diversification of immunoglobulins involved in immune responseGO:000220830.012
g1 s transition of mitotic cell cycleGO:0000082780.012
lymphocyte activation involved in immune responseGO:0002285200.012
response to nitrogen compoundGO:19016981840.012
regulation of ion transportGO:00432691890.012
regulation of transforming growth factor beta receptor signaling pathwayGO:0017015480.012
positive regulation of response to alcoholGO:190142130.012
compound eye developmentGO:004874910.012
endomembrane system organizationGO:00102561960.012
b cell activationGO:0042113330.012
regulation of histone modificationGO:0031056470.012
viral life cycleGO:00190581320.012
nucleus organizationGO:0006997280.012
cellular macromolecule catabolic processGO:00442653800.012
negative regulation of developmental processGO:00510932470.012
Zebrafish Worm
peripheral nervous system developmentGO:000742220.012
tissue regenerationGO:004224630.012
gene silencingGO:0016458490.012
adaptive immune responseGO:0002250490.012
cardiac muscle contractionGO:0060048340.012
nucleobase containing compound transportGO:0015931510.012
organophosphate catabolic processGO:00464344300.012
nucleoside triphosphate metabolic processGO:00091414220.011
detection of stimulusGO:0051606850.011
negative regulation of cell cycleGO:00457861930.011
positive regulation of secretionGO:00510471160.011
intracellular steroid hormone receptor signaling pathwayGO:0030518610.011
regulation of cellular ketone metabolic processGO:0010565500.011
purine containing compound catabolic processGO:00725234110.011
hard palate developmentGO:006002210.011
negative regulation of phosphorus metabolic processGO:00105632670.011
myosin filament assemblyGO:003103420.011
secretion by cellGO:00329402260.011
modification dependent macromolecule catabolic processGO:00436322120.011
mitotic nuclear divisionGO:00070671190.011
dna replicationGO:00062601160.011
regulation of multi organism processGO:00439001570.011
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.011
regulation of cardiac muscle cell proliferationGO:006004340.011
intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediatorGO:0042771230.011
regulation of viral processGO:00507921030.011
striated muscle myosin thick filament assemblyGO:007168820.011
rna export from nucleusGO:0006405330.010
positive regulation of erk1 and erk2 cascadeGO:0070374750.010
lymphocyte activationGO:00466491330.010
glycosyl compound catabolic processGO:19016584130.010
multi organism metabolic processGO:0044033410.010
hematopoietic or lymphoid organ developmentGO:00485341860.010
heart morphogenesisGO:0003007480.010
positive regulation of mrna processingGO:0050685170.010
cellular metal ion homeostasisGO:00068751460.010
sex differentiationGO:0007548450.010
ribonucleoside triphosphate catabolic processGO:00092033910.010
modification dependent protein catabolic processGO:00199412090.010
oocyte developmentGO:004859910.010
carbohydrate derivative biosynthetic processGO:19011372070.010
purine ribonucleoside triphosphate catabolic processGO:00092073910.010
negative regulation of phosphate metabolic processGO:00459362670.010

SFPQ disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:8634310.057
central nervous system diseaseDOID:3311860.057
musculoskeletal system diseaseDOID:172230.038
sensory system diseaseDOID:00501552030.029
eye and adnexa diseaseDOID:14921500.029
neurodegenerative diseaseDOID:12891020.015
muscular diseaseDOID:00800001140.015