Homo sapiens

0 known processes

SMPD3

sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)

(Aliases: MGC138443,NSMASE2,FLJ22593)

SMPD3 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
post embryonic developmentGO:000979120.060
lipid metabolic processGO:00066293810.055
cellular ketone metabolic processGO:0042180800.052
transmembrane transportGO:00550853990.048
cation transportGO:00068123310.046
actin filament based processGO:00300292240.042
regulation of cellular ketone metabolic processGO:0010565500.042
positive regulation of cellular component organizationGO:00511303760.042
locomotory behaviorGO:000762610.042
small gtpase mediated signal transductionGO:0007264780.042
cellular amino acid metabolic processGO:00065201160.042
system processGO:00030083490.042
regulation of cellular amine metabolic processGO:0033238110.041
regulation of cellular amino acid metabolic processGO:000652160.041
amine metabolic processGO:0009308440.041
multicellular organismal agingGO:001025930.038
cellular lipid metabolic processGO:00442553030.037
regulation of cell cycleGO:00517263930.037
negative regulation of catalytic activityGO:00430863350.037
cellular amine metabolic processGO:0044106410.036
nervous system developmentGO:00073992930.036
vesicle mediated transportGO:00161923710.036
positive regulation of transportGO:00510503360.035
determination of adult lifespanGO:000834020.035
cell morphogenesisGO:00009022960.035
segmentationGO:003528240.035
cell developmentGO:00484683280.034
secretion by cellGO:00329402260.034
regulation of locomotionGO:00400123290.034
oogenesisGO:004847720.034
regulation of transferase activityGO:00513383550.033
positive regulation of cell deathGO:00109422630.033
regulation of cell differentiationGO:00455953930.033
secretionGO:00469032540.033
cellular component morphogenesisGO:00329893140.033
positive regulation of phosphorylationGO:00423273940.033
regulation of protein localizationGO:00328802960.033
female gamete generationGO:000729220.033
immune responseGO:00069553070.033
negative regulation of protein metabolic processGO:00512483910.032
cell adhesionGO:00071553250.032
organophosphate catabolic processGO:00464344300.032
ribonucleotide catabolic processGO:00092614050.032
regulation of cellular component biogenesisGO:00440872810.032
negative regulation of cellular protein metabolic processGO:00322693530.032
mapk cascadeGO:00001652880.031
positive regulation of apoptotic processGO:00430652460.031
ribonucleoside triphosphate metabolic processGO:00091994120.031
neuromuscular junction developmentGO:000752830.031
biological adhesionGO:00226103310.031
cell projection organizationGO:00300302520.030
negative regulation of phosphorus metabolic processGO:00105632670.030
nucleoside triphosphate metabolic processGO:00091414220.030
regulation of kinase activityGO:00435493140.030
ion transmembrane transportGO:00342203380.030
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.030
purine nucleoside triphosphate catabolic processGO:00091463920.030
nucleotide catabolic processGO:00091664080.029
cellular macromolecule catabolic processGO:00442653800.029
regulation of sequence specific dna binding transcription factor activityGO:00510902110.029
positive regulation of programmed cell deathGO:00430682490.029
chemical homeostasisGO:00488783060.029
nucleoside triphosphate catabolic processGO:00091433940.029
positive regulation of catabolic processGO:00098963100.029
ribonucleoside catabolic processGO:00424544060.029
glycosyl compound catabolic processGO:19016584130.029
purine ribonucleoside triphosphate metabolic processGO:00092054110.028
ras protein signal transductionGO:0007265730.028
cation transmembrane transportGO:00986552380.028
purine nucleoside triphosphate metabolic processGO:00091444120.028
positive regulation of hydrolase activityGO:00513453310.028
purine ribonucleoside catabolic processGO:00461303980.028
response to oxygen containing compoundGO:19017003690.028
negative regulation of programmed cell deathGO:00430693210.028
regenerationGO:003109940.028
regulation of protein kinase activityGO:00458592890.028
positive regulation of immune system processGO:00026842830.028
positive regulation of cellular catabolic processGO:00313312840.027
ribonucleoside triphosphate catabolic processGO:00092033910.027
memoryGO:000761330.027
negative regulation of phosphate metabolic processGO:00459362670.027
protein catabolic processGO:00301633250.027
regulation of mapk cascadeGO:00434082620.027
mitotic cell cycleGO:00002783260.027
purine containing compound catabolic processGO:00725234110.027
purine ribonucleoside metabolic processGO:00461284370.027
hindbrain developmentGO:003090230.027
signal transduction by phosphorylationGO:00230142970.027
metal ion transportGO:00300012720.026
regulation of proteolysisGO:00301622930.026
cellular response to oxygen containing compoundGO:19017012760.026
purine nucleoside catabolic processGO:00061523980.026
regulation of purine nucleotide metabolic processGO:19005422640.026
cytoplasmic transportGO:00164823790.026
dephosphorylationGO:00163112090.026
oxidation reduction processGO:00551143960.026
gtp catabolic processGO:00061842370.026
protein modification by small protein conjugationGO:00324463420.026
regulation of cell motilityGO:20001452990.025
carbohydrate metabolic processGO:00059752070.025
nucleoside catabolic processGO:00091644080.025
response to abiotic stimulusGO:00096283360.025
purine ribonucleoside triphosphate catabolic processGO:00092073910.025
negative regulation of cell deathGO:00605483450.025
negative regulation of multicellular organismal processGO:00512413170.025
purine ribonucleotide catabolic processGO:00091544040.025
negative regulation of cellular component organizationGO:00511292350.025
nucleoside phosphate catabolic processGO:19012924120.024
cellular response to endogenous stimulusGO:00714953360.024
negative regulation of cell proliferationGO:00082852280.024
neurological system processGO:00508771630.024
positive regulation of cellular amine metabolic processGO:003324070.024
defense responseGO:00069523150.024
cellular protein catabolic processGO:00442572610.024
regulation of anatomical structure morphogenesisGO:00226032860.024
cellular macromolecular complex assemblyGO:00346223240.024
guanosine containing compound catabolic processGO:19010692390.024
divalent inorganic cation transportGO:00725111580.024
mitotic cell cycle processGO:19030472860.024
rho protein signal transductionGO:0007266260.024
positive regulation of cell proliferationGO:00082843010.023
blastoderm segmentationGO:000735020.023
regulation of secretion by cellGO:19035301770.023
negative regulation of developmental processGO:00510932470.023
purine nucleotide catabolic processGO:00061954050.023
response to external biotic stimulusGO:00432072610.023
negative regulation of protein modification processGO:00314002000.023
regulation of cytokine productionGO:00018172320.023
regulation of nucleotide metabolic processGO:00061402690.023
neurotransmitter secretionGO:000726940.023
motor neuron axon guidanceGO:000804520.023
protein ubiquitinationGO:00165673140.023
positive regulation of developmental processGO:00510943140.023
positive regulation of cellular amino acid metabolic processGO:004576430.023
response to lipidGO:00339932060.023
inorganic ion transmembrane transportGO:00986602310.023
protein processingGO:00164852260.023
matingGO:000761810.022
inorganic cation transmembrane transportGO:00986621940.022
spinal cord developmentGO:002151040.022
protein maturationGO:00516042330.022
apoptotic signaling pathwayGO:00971902680.022
positive regulation of protein phosphorylationGO:00019343130.022
chromatin organizationGO:00063253510.022
cellular response to dna damage stimulusGO:00069743790.022
single organism membrane organizationGO:00448022680.022
protein localization to organelleGO:00333652800.022
regulation of response to external stimulusGO:00321012220.022
regulation of cellular response to stressGO:00801352440.022
single organism cellular localizationGO:19025803320.022
lipid biosynthetic processGO:00086101770.022
negative regulation of apoptotic processGO:00430663160.022
proteolysis involved in cellular protein catabolic processGO:00516032440.021
regulation of establishment of protein localizationGO:00702012420.021
anterior posterior axis specificationGO:000994820.021
membrane organizationGO:00610242920.021
chromatin modificationGO:00165682980.021
cellular protein complex assemblyGO:00436231880.021
negative regulation of cellular amine metabolic processGO:003323930.021
adult locomotory behaviorGO:000834410.021
regulation of purine nucleotide catabolic processGO:00331212050.021
regulation of cytoskeleton organizationGO:00514931770.020
innate immune responseGO:00450871780.020
regulation of secretionGO:00510461940.020
associative learningGO:000830610.020
response to other organismGO:00517072610.020
guanosine containing compound metabolic processGO:19010682440.020
regulation of cell developmentGO:00602841610.020
negative regulation of cellular amino acid metabolic processGO:004576320.020
oocyte differentiationGO:000999420.020
neurogenesisGO:00220081690.019
gtp metabolic processGO:00460392390.019
regulation of intracellular transportGO:00323861950.019
histone modificationGO:00165702510.019
modification dependent macromolecule catabolic processGO:00436322120.019
positive regulation of organelle organizationGO:00106381950.019
regulation of cellular component movementGO:00512703340.019
epithelium developmentGO:00604292270.019
carbohydrate derivative biosynthetic processGO:19011372070.019
regulation of protein transportGO:00512232130.019
regulation of gtpase activityGO:00430871800.019
small molecule biosynthetic processGO:00442831570.019
peripheral nervous system developmentGO:000742220.019
enzyme linked receptor protein signaling pathwayGO:00071673030.019
oocyte developmentGO:004859910.019
positive regulation of cell differentiationGO:00455972110.019
covalent chromatin modificationGO:00165692540.019
positive regulation of kinase activityGO:00336742040.019
regulation of protein complex assemblyGO:00432541470.018
negative regulation of phosphorylationGO:00423261740.018
inner ear morphogenesisGO:004247240.018
actin cytoskeleton organizationGO:00300362070.018
regulation of gtp catabolic processGO:00331241800.018
negative regulation of intracellular signal transductionGO:19025321830.018
ubiquitin dependent protein catabolic processGO:00065112060.018
response to biotic stimulusGO:00096072760.018
regulation of ion transportGO:00432691890.018
regulation of cell cycle processGO:00105642660.018
regulation of mitotic cell cycleGO:00073461890.018
regulation of nucleoside metabolic processGO:00091182090.018
metencephalon developmentGO:002203720.018
positive regulation of nucleotide metabolic processGO:00459812300.018
positive regulation of transferase activityGO:00513472270.018
oligosaccharide biosynthetic processGO:000931230.018
cytokine productionGO:00018162470.018
positive regulation of gtp catabolic processGO:00331261660.018
single organism carbohydrate metabolic processGO:00447231930.018
positive regulation of synaptic transmissionGO:005080640.018
neuron differentiationGO:00301821380.018
regulation of immune responseGO:00507762010.018
negative regulation of hydrolase activityGO:00513461820.018
regulation of neurotransmitter secretionGO:004692830.018
cardiac muscle cell contractionGO:008600340.018
monocarboxylic acid metabolic processGO:00327871850.018
regulation of cell morphogenesisGO:00226041530.018
negative regulation of cell cycleGO:00457861930.018
modification dependent protein catabolic processGO:00199412090.017
positive regulation of tooth mineralizationGO:007017220.017
negative regulation of protein phosphorylationGO:00019331400.017
positive regulation of nucleoside metabolic processGO:00459791860.017
intracellular protein transportGO:00068862700.017
cation homeostasisGO:00550801890.017
positive regulation of gtpase activityGO:00435471660.017
rhythmic behaviorGO:000762220.017
metal ion homeostasisGO:00550651690.017
posttranscriptional regulation of gene expressionGO:00106082130.017
regulation of cell migrationGO:00303342890.017
positive regulation of purine nucleotide catabolic processGO:00331231850.017
endomembrane system organizationGO:00102561960.017
anatomical structure formation involved in morphogenesisGO:00486462840.017
positive regulation of purine nucleotide metabolic processGO:19005442270.017
regulation of apoptotic signaling pathwayGO:20012331750.017
generation of neuronsGO:00486991520.017
microtubule based processGO:00070172100.017
regulation of actin filament based processGO:00329701410.017
positive regulation of mapk cascadeGO:00434101900.017
ion homeostasisGO:00508012300.017
positive regulation of nucleotide catabolic processGO:00308131850.017
protein localization to membraneGO:00726571600.017
forebrain generation of neuronsGO:002187230.017
positive regulation of cytokine productionGO:00018191670.016
cell part morphogenesisGO:00329901370.016
negative regulation of organelle organizationGO:00106391260.016
spermatid differentiationGO:004851540.016
regulation of cell growthGO:00015581350.016
cell growthGO:00160491600.016
negative regulation of cell differentiationGO:00455961710.016
anterior posterior axis specification embryoGO:000859520.016
actin filament based movementGO:0030048170.016
regulation of protein processingGO:00706131500.016
immune system developmentGO:00025201950.016
regulation of nucleotide catabolic processGO:00308112050.016
nerve developmentGO:002167540.016
response to hormoneGO:00097251750.016
single organismal cell cell adhesionGO:00163371480.016
protein targetingGO:00066051870.016
morphogenesis of embryonic epitheliumGO:001633140.016
regulation of protein catabolic processGO:00421761550.016
negative regulation of protein processingGO:00109551420.016
divalent metal ion transportGO:00708381520.016
cell fate determinationGO:000170930.016
cellular response to cytokine stimulusGO:00713451810.016
endosomal transportGO:00161971290.016
regulation of small gtpase mediated signal transductionGO:00510561560.016
compound eye developmentGO:004874910.016
positive regulation of protein kinase activityGO:00458601900.016
regulation of protein maturationGO:19033171500.015
regulation of ras gtpase activityGO:00323181280.015
negative regulation of protein maturationGO:19033181420.015
regulation of i kappab kinase nf kappab signalingGO:00431221620.015
organic hydroxy compound metabolic processGO:19016151470.015
reactive oxygen species biosynthetic processGO:190340940.015
cell morphogenesis involved in differentiationGO:00009041440.015
regulation of actin cytoskeleton organizationGO:00329561160.015
chemotaxisGO:00069351570.015
response to cytokineGO:00340972320.015
regulation of synaptic plasticityGO:004816730.015
growthGO:00400072020.015
positive regulation of sequence specific dna binding transcription factor activityGO:00510911310.015
hemopoiesisGO:00300971800.015
i kappab kinase nf kappab signalingGO:00072491660.015
negative regulation of transportGO:00510511760.015
tripartite regional subdivisionGO:000735120.015
regulation of multi organism processGO:00439001570.015
regulation of ras protein signal transductionGO:00465781550.015
sensory perceptionGO:00076001030.015
protein oligomerizationGO:00512591730.015
central nervous system developmentGO:00074171230.015
photoreceptor cell differentiationGO:004653020.015
organonitrogen compound biosynthetic processGO:19015662000.015
circadian behaviorGO:004851220.015
organ formationGO:004864530.015
calcium ion transportGO:00068161470.015
actin mediated cell contractionGO:0070252120.015
regulation of protein serine threonine kinase activityGO:00719001790.015
neuron developmentGO:00486661130.014
spermatid developmentGO:000728640.014
limbic system developmentGO:002176130.014
positive regulation of i kappab kinase nf kappab signalingGO:00431231320.014
cell differentiation in spinal cordGO:002151510.014
microtubule cytoskeleton organizationGO:00002261760.014
positive regulation of secretion by cellGO:19035321080.014
sex determinationGO:000753030.014
maintenance of locationGO:00512351120.014
reactive nitrogen species metabolic processGO:200105730.014
negative regulation of locomotionGO:00400131180.014
multi organism cellular processGO:00447641560.014
myeloid cell differentiationGO:00300991170.014
negative regulation of proteolysisGO:00458611320.014
neuron fate commitmentGO:004866320.014
epidermis morphogenesisGO:004873030.014
regulation of ion transmembrane transportGO:00347651320.014
regulation of dna metabolic processGO:00510521530.014
cell cycle phase transitionGO:00447701730.014
regulation of axon guidanceGO:190266730.014
regulation of cell projection organizationGO:00313441070.014
single organism cell adhesionGO:00986021790.014
fatty acid metabolic processGO:00066311150.014
regulation of cell adhesionGO:00301551660.014
regulation of growthGO:00400081650.014
response to bacteriumGO:00096171440.014
cell cell signalingGO:00072671550.014
regulation of neural precursor cell proliferationGO:200017740.014
positive regulation of ras gtpase activityGO:00323201170.014
morphogenesis of a polarized epitheliumGO:000173830.014
response to nitrogen compoundGO:19016981840.014
wnt signaling pathway involved in wound healing spreading of epidermal cellsGO:003565910.014
positive regulation of cell cycleGO:00457871400.014
cell divisionGO:00513011680.014
establishment of protein localization to organelleGO:00725941720.014
regulation of transmembrane transportGO:00347621390.014
response to organic cyclic compoundGO:00140702040.014
cellular response to lipidGO:00713961270.014
proteasomal protein catabolic processGO:00104981760.014
positive regulation of cellular component biogenesisGO:00440891580.014
cellular homeostasisGO:00197251960.014
actin filament organizationGO:00070151280.014
nuclear transportGO:00511691790.014
syncytium formation by plasma membrane fusionGO:000076820.014
neuroblast proliferationGO:000740540.014
monovalent inorganic cation transportGO:00156721280.014
regulation of metal ion transportGO:00109591200.013
organelle assemblyGO:00709251760.013
taxisGO:00423301570.013
organic acid biosynthetic processGO:0016053970.013
hematopoietic or lymphoid organ developmentGO:00485341860.013
long term memoryGO:000761620.013
regulation of reactive oxygen species biosynthetic processGO:190342630.013
response to fungusGO:000962040.013
negative regulation of transferase activityGO:00513481240.013
cardiovascular system developmentGO:00723582620.013
methylationGO:00322591060.013
positive regulation of secretionGO:00510471160.013
epithelial cell differentiationGO:00308551410.013
cell projection morphogenesisGO:00488581290.013
anion transportGO:00068201610.013
visual behaviorGO:000763220.013
viral processGO:00160321460.013
regulation of axon extension involved in axon guidanceGO:004884120.013
interspecies interaction between organismsGO:00444191560.013
mitotic cell cycle phase transitionGO:00447721620.013
regulation of neuronal synaptic plasticityGO:004816810.013
establishment or maintenance of bipolar cell polarityGO:006124520.013
positive regulation of locomotionGO:00400171860.013
glycoprotein metabolic processGO:00091001100.013
head developmentGO:00603221080.013
nucleocytoplasmic transportGO:00069131760.013
sensory perception of smellGO:000760820.013
cerebellum developmentGO:002154920.013
regulation of meiotic cell cycleGO:005144540.013
glial cell migrationGO:000834740.013
sequestering of metal ionGO:0051238240.013
cellular chemical homeostasisGO:00550821800.013
regulation of bindingGO:00510981110.013
positive regulation of dermatome developmentGO:006118430.013
regulation of viral processGO:00507921030.013
nitrogen compound transportGO:00717051910.013
circulatory system developmentGO:00723592620.013
symbiosis encompassing mutualism through parasitismGO:00444031560.013
establishment or maintenance of apical basal cell polarityGO:003508820.013
t cell differentiation in thymusGO:003307740.012
response to growth factorGO:00708482050.012
positive regulation of protein transportGO:00512221350.012
rna processingGO:00063962550.012
regulation of dephosphorylationGO:0035303960.012
organophosphate biosynthetic processGO:00904071630.012
negative regulation of catabolic processGO:00098951040.012
cellular ion homeostasisGO:00068731680.012
purine ribonucleoside monophosphate metabolic processGO:00091671860.012
synaptic vesicle recyclingGO:003646530.012
protein acylationGO:00435431380.012
sequestering of calcium ionGO:0051208170.012
carboxylic acid biosynthetic processGO:0046394970.012
response to axon injuryGO:004867810.012
viral life cycleGO:00190581320.012
lipid modificationGO:0030258840.012
positive regulation of reactive oxygen species biosynthetic processGO:190342820.012
cell projection assemblyGO:00300311260.012
response to virusGO:00096151260.012
cellular metal ion homeostasisGO:00068751460.012
negative regulation of kinase activityGO:00336731060.012
reactive oxygen species metabolic processGO:0072593750.012
regulation of symbiosis encompassing mutualism through parasitismGO:00439031090.012
protein modification by small protein removalGO:0070646920.012
positive regulation of cellular component movementGO:00512721810.012
cell activationGO:00017752130.012
positive regulation of immune responseGO:00507781590.012
wnt signaling pathwayGO:00160551560.012
cellular response to nitrogen compoundGO:19016991440.012
negative regulation of cellular catabolic processGO:0031330830.012
negative regulation of cell motilityGO:20001461040.012
myoblast fusionGO:000752010.012
atp metabolic processGO:00460341760.012
tissue regenerationGO:004224630.012
somitogenesisGO:000175620.012
purine nucleoside monophosphate metabolic processGO:00091261860.012
stem cell divisionGO:001714520.012
organelle fissionGO:00482851490.012
startle responseGO:000196430.012
mitochondrion organizationGO:00070051560.012
regulation of phosphatase activityGO:0010921810.012
macromolecule methylationGO:0043414970.012
embryonic epithelial tube formationGO:000183840.012
forebrain neuron differentiationGO:002187930.012
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.012
establishment of protein localization to membraneGO:00901501210.012
regulation of membrane potentialGO:0042391950.011
regulation of protein stabilityGO:0031647870.011
regulation of cellular protein catabolic processGO:1903362960.011
cranial nerve developmentGO:002154540.011
protein polymerizationGO:0051258710.011
regulation of cytoplasmic transportGO:19036491490.011
cellular response to hormone stimulusGO:00328701250.011
regulation of peptidase activityGO:00525471800.011
cytokine secretionGO:0050663640.011
alcohol metabolic processGO:00060661140.011
forebrain regionalizationGO:002187130.011
regulation of proteolysis involved in cellular protein catabolic processGO:1903050910.011
rab protein signal transductionGO:003248240.011
regulation of endopeptidase activityGO:00525481700.011
cellular response to growth factor stimulusGO:00713631970.011
cellular response to organonitrogen compoundGO:00714171240.011
sensory perception of painGO:001923340.011
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.011
negative regulation of protein kinase activityGO:0006469980.011
positive regulation of proteolysisGO:00458621420.011
response to organonitrogen compoundGO:00102431560.011
regulation of defense responseGO:00313471540.011
negative regulation of cellular component movementGO:00512711060.011
negative regulation of cell growthGO:0030308830.011
regulation of reactive oxygen species metabolic processGO:2000377410.011
neuron projection developmentGO:00311751060.011
immune effector processGO:00022521590.011
negative regulation of axonogenesisGO:005077140.011
leukocyte activationGO:00453211640.011
monocarboxylic acid biosynthetic processGO:0072330670.011
regulation of protein secretionGO:0050708860.011
plasma membrane organizationGO:00070091150.011
establishment of planar polarityGO:000173630.011
sleepGO:003043120.011
protein localization to nucleusGO:00345041360.011
regulation of protein polymerizationGO:0032271630.011
intrinsic apoptotic signaling pathwayGO:00971931270.011
meiotic chromosome segregationGO:004513240.011
positive regulation of protein serine threonine kinase activityGO:00719021190.011
brain developmentGO:0007420970.011
neural tube formationGO:000184130.011
positive regulation of cell migrationGO:00303351720.011
cell substrate adhesionGO:00315891320.011
ribonucleoside monophosphate metabolic processGO:00091611870.011
heart formationGO:006091420.011
rna interferenceGO:001624640.011
negative regulation of cell migrationGO:00303361020.011
positive regulation of cell motilityGO:20001471770.011
blood circulationGO:00080151130.011
post embryonic organ developmentGO:004856910.011

SMPD3 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:00146672950.023
musculoskeletal system diseaseDOID:172230.022
nervous system diseaseDOID:8634310.022
central nervous system diseaseDOID:3311860.022
sensory system diseaseDOID:00501552030.022
bone diseaseDOID:0080001880.019
connective tissue diseaseDOID:651090.019
disease of cellular proliferationDOID:145661740.018
cancerDOID:1621670.018
organ system cancerDOID:00506861640.016
inherited metabolic disorderDOID:6552420.016
eye and adnexa diseaseDOID:14921500.016
neurodegenerative diseaseDOID:12891020.015
immune system diseaseDOID:29141550.015
eye diseaseDOID:56141490.013
disease of mental healthDOID:150700.012
brain diseaseDOID:936730.012