Homo sapiens

133 known processes

UPF1

UPF1 regulator of nonsense transcripts homolog (yeast)

(Aliases: RENT1,NORF1,FLJ43809,FLJ46894,pNORF1,KIAA0221,HUPF1)

UPF1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
mrna catabolic processGO:0006402561.000
mrna metabolic processGO:00160711751.000
rna catabolic processGO:0006401711.000
nuclear transcribed mrna catabolic processGO:0000956481.000
cellular macromolecule catabolic processGO:00442653801.000
nuclear transcribed mrna catabolic process nonsense mediated decayGO:0000184231.000
male genitalia developmentGO:003053910.983
translationGO:00064121320.914
female gamete generationGO:000729220.892
intracellular mrna localizationGO:000829810.884
Yeast
regulation of translationGO:0006417890.866
nucleic acid phosphodiester bond hydrolysisGO:00903051020.730
posttranscriptional regulation of gene expressionGO:00106082130.670
posttranscriptional gene silencing by rnaGO:0035194250.636
Worm
rna phosphodiester bond hydrolysisGO:0090501350.626
anatomical structure homeostasisGO:00602491000.621
anterior posterior axis specificationGO:000994820.585
reproductive processGO:00224141060.564
Worm
rna localizationGO:0006403410.551
Yeast
telomere maintenanceGO:0000723320.535
oocyte differentiationGO:000999420.505
blastoderm segmentationGO:000735020.475
ribonucleoprotein complex biogenesisGO:00226131160.475
multicellular organismal agingGO:001025930.456
mrna processingGO:00063971330.455
anterior posterior axis specification embryoGO:000859520.425
rna processingGO:00063962550.395
telomere organizationGO:0032200330.377
ribonucleoprotein complex assemblyGO:0022618780.349
oocyte developmentGO:004859910.342
segmentationGO:003528240.301
negative regulation of gene silencing by rnaGO:006096730.297
defense response to fungusGO:005083240.286
single organism cellular localizationGO:19025803320.269
nuclear transcribed mrna catabolic process no go decayGO:007096620.262
glycerophospholipid metabolic processGO:0006650840.261
sex differentiationGO:0007548450.229
Worm
regulation of meiotic cell cycleGO:005144540.216
post embryonic developmentGO:000979120.207
positive regulation of translationGO:0045727350.207
regulation of cell maturationGO:190342930.201
vesicle mediated transportGO:00161923710.200
memoryGO:000761330.200
tripartite regional subdivisionGO:000735120.196
phosphatidylinositol metabolic processGO:0046488530.196
negative regulation of posttranscriptional gene silencingGO:006014930.181
determination of adult lifespanGO:000834020.176
oogenesisGO:004847720.173
ribonucleoprotein complex disassemblyGO:003298870.156
single organism reproductive processGO:0044702980.138
Worm
cellular lipid metabolic processGO:00442553030.133
cytoplasmic mrna processing body assemblyGO:0033962100.132
methylationGO:00322591060.131
dephosphorylationGO:00163112090.123
mitotic cell cycle processGO:19030472860.105
enzyme linked receptor protein signaling pathwayGO:00071673030.101
embryo developmentGO:00097901230.100
Zebrafish Worm
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.099
reproductive system developmentGO:0061458560.092
Worm
protein autophosphorylationGO:00467771230.090
defense responseGO:00069523150.089
translational initiationGO:0006413480.085
response to fungusGO:000962040.085
lipid metabolic processGO:00066293810.085
regulation of mrna processingGO:0050684480.078
rna interferenceGO:001624640.077
Worm
developmental process involved in reproductionGO:0003006660.074
Worm
gene silencing by mirnaGO:0035195230.073
wnt signaling pathwayGO:00160551560.073
phospholipid metabolic processGO:0006644990.072
organelle assemblyGO:00709251760.066
receptor mediated endocytosisGO:0006898840.064
nucleoside catabolic processGO:00091644080.063
nucleoside phosphate catabolic processGO:19012924120.063
phosphatidylinositol phosphorylationGO:0046854240.063
telomere assemblyGO:003220250.061
cell cell signalingGO:00072671550.061
glycerolipid metabolic processGO:00464861070.061
protein complex disassemblyGO:0043241520.060
rna splicingGO:00083801310.060
primary mirna processingGO:003105330.059
behaviorGO:00076101120.058
cell developmentGO:00484683280.057
dna replicationGO:00062601160.057
gonad developmentGO:0008406340.054
Worm
ribonucleoprotein complex subunit organizationGO:0071826810.054
cellular response to dna damage stimulusGO:00069743790.053
lipid modificationGO:0030258840.051
reproductive structure developmentGO:0048608550.050
Worm
development of primary sexual characteristicsGO:0045137350.050
Worm
nucleobase containing compound transportGO:0015931510.047
regulation of cell cycleGO:00517263930.045
regulation of meiosisGO:004002030.045
response to external biotic stimulusGO:00432072610.043
rna export from nucleusGO:0006405330.043
reproductionGO:0000003630.042
posttranscriptional gene silencingGO:0016441250.041
Worm
intracellular protein transportGO:00068862700.041
gene silencingGO:0016458490.040
Yeast Worm
nucleoside monophosphate catabolic processGO:00091251590.040
agingGO:0007568660.039
regulation of mrna metabolic processGO:1903311530.038
regulation of wnt signaling pathwayGO:00301111230.037
defense response to other organismGO:00985421290.036
pattern specification processGO:0007389430.035
regulation of gene expression epigeneticGO:0040029730.035
Yeast Mouse Worm
embryonic axis specificationGO:000057850.035
microtubule cytoskeleton organizationGO:00002261760.034
vesicle localizationGO:0051648260.034
regulation of dna metabolic processGO:00510521530.033
synaptic transmissionGO:0007268610.032
regulation of growthGO:00400081650.032
nuclear divisionGO:00002801280.032
organophosphate catabolic processGO:00464344300.032
protein methylationGO:0006479740.031
establishment of rna localizationGO:0051236390.031
neural crest cell developmentGO:001403230.031
gene silencing by rnaGO:0031047260.029
Worm
neuromuscular synaptic transmissionGO:000727450.029
ncrna metabolic processGO:00346601080.029
locomotory behaviorGO:000762610.029
rna 3 end processingGO:0031123350.029
hemopoiesisGO:00300971800.029
nucleic acid transportGO:0050657390.028
protein alkylationGO:0008213740.028
positive regulation of transferase activityGO:00513472270.028
purine nucleoside monophosphate catabolic processGO:00091281580.027
regulation of apoptotic signaling pathwayGO:20012331750.027
regulation of cell divisionGO:00513021160.027
symbiosis encompassing mutualism through parasitismGO:00444031560.026
nuclear transportGO:00511691790.026
cellular macromolecular complex assemblyGO:00346223240.026
cellular amine metabolic processGO:0044106410.025
regionalizationGO:0003002290.024
regulation of cell differentiationGO:00455953930.024
regulation of locomotionGO:00400123290.024
protein localization to organelleGO:00333652800.024
negative regulation of programmed cell deathGO:00430693210.024
regulation of dephosphorylationGO:0035303960.024
telomere maintenance via telomeraseGO:000700480.024
negative regulation of mrna catabolic processGO:190237340.024
hormone metabolic processGO:0042445610.024
mrna transportGO:0051028300.023
cellular amino acid metabolic processGO:00065201160.023
response to other organismGO:00517072610.023
microtubule based processGO:00070172100.023
matingGO:000761810.023
organelle fissionGO:00482851490.023
protein targetingGO:00066051870.023
sexual reproductionGO:0019953370.023
regulation of cellular amino acid metabolic processGO:000652160.022
embryo development ending in birth or egg hatchingGO:0009792340.022
positive regulation of cell deathGO:00109422630.021
dna repairGO:00062811980.021
viral processGO:00160321460.021
reactive oxygen species metabolic processGO:0072593750.020
nucleocytoplasmic transportGO:00069131760.020
cellular protein complex disassemblyGO:0043624360.020
spermatid differentiationGO:004851540.020
nitrogen compound transportGO:00717051910.020
positive regulation of cellular amine metabolic processGO:003324070.020
macromolecule methylationGO:0043414970.020
negative regulation of cellular component organizationGO:00511292350.020
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377890.020
histone mrna catabolic processGO:0071044100.019
multi organism reproductive processGO:0044703540.019
embryonic morphogenesisGO:0048598850.019
Worm
negative regulation of multi organism processGO:0043901920.019
cytoplasmic transportGO:00164823790.019
negative regulation of cellular amine metabolic processGO:003323930.019
cellular component disassemblyGO:0022411920.019
hematopoietic or lymphoid organ developmentGO:00485341860.018
cellular ketone metabolic processGO:0042180800.018
adult locomotory behaviorGO:000834410.018
spermatid developmentGO:000728640.018
synaptic vesicle localizationGO:009747950.018
purine ribonucleoside metabolic processGO:00461284370.017
cell morphogenesisGO:00009022960.017
neurological system processGO:00508771630.017
covalent chromatin modificationGO:00165692540.017
mrna splicing via spliceosomeGO:0000398890.016
regulation of nuclear divisionGO:0051783650.016
modification dependent macromolecule catabolic processGO:00436322120.016
growthGO:00400072020.016
male sex differentiationGO:0046661250.016
immune system developmentGO:00025201950.016
regulation of cellular amine metabolic processGO:0033238110.015
spindle elongationGO:005123140.015
response to organic cyclic compoundGO:00140702040.015
nuclear exportGO:0051168690.015
regulation of homeostatic processGO:00328441210.015
regulation of cell developmentGO:00602841610.015
peripheral nervous system developmentGO:000742220.015
mitotic cell cycleGO:00002783260.015
alternative mrna splicing via spliceosomeGO:0000380270.015
rna phosphodiester bond hydrolysis endonucleolyticGO:0090502150.015
rna transportGO:0050658390.015
regulation of transferase activityGO:00513383550.014
system processGO:00030083490.014
chordate embryonic developmentGO:0043009340.014
negative regulation of viral genome replicationGO:0045071350.014
single organism membrane organizationGO:00448022680.014
regulation of extrinsic apoptotic signaling pathwayGO:2001236850.014
long term memoryGO:000761620.014
cytoplasmic translational initiationGO:000218360.014
mapk cascadeGO:00001652880.014
skeletal system developmentGO:0001501790.013
regulation of symbiosis encompassing mutualism through parasitismGO:00439031090.013
establishment of protein localization to plasma membraneGO:0090002680.013
regulation of multi organism processGO:00439001570.013
negative regulation of hydrolase activityGO:00513461820.013
negative regulation of apoptotic signaling pathwayGO:2001234970.013
nucleoside triphosphate metabolic processGO:00091414220.013
negative regulation of apoptotic processGO:00430663160.013
amine metabolic processGO:0009308440.013
lipid phosphorylationGO:0046834310.013
endocytosisGO:00068971590.013
negative regulation of locomotionGO:00400131180.013
synaptic vesicle transportGO:004848950.013
circadian sleep wake cycle processGO:002241020.012
cell growthGO:00160491600.012
rna splicing via transesterification reactionsGO:0000375900.012
meiosis iGO:000712740.012
negative regulation of cellular amino acid metabolic processGO:004576320.012
multicellular organismal reproductive processGO:0048609400.012
rhythmic behaviorGO:000762220.012
positive regulation of wnt signaling pathwayGO:0030177540.012
interspecies interaction between organismsGO:00444191560.012
monocarboxylic acid metabolic processGO:00327871850.011
gamete generationGO:0007276250.011
cell divisionGO:00513011680.011
regulation of cell growthGO:00015581350.011
7 methylguanosine mrna cappingGO:000637070.011
mitotic spindle elongationGO:000002240.011
positive regulation of apoptotic processGO:00430652460.011
protein catabolic processGO:00301633250.011
ribonucleoside monophosphate metabolic processGO:00091611870.011
reactive nitrogen species metabolic processGO:200105730.011
proteasomal protein catabolic processGO:00104981760.011
cellular response to starvationGO:0009267580.011
circadian behaviorGO:004851220.011
cellular response to nitrogen compoundGO:19016991440.011
ncrna catabolic processGO:0034661140.011
regulation of cell activationGO:00508651250.011
regulation of protein catabolic processGO:00421761550.011
positive regulation of mapk cascadeGO:00434101900.011
lymphocyte homeostasisGO:000226040.011
establishment of vesicle localizationGO:0051650230.011
purine ribonucleoside monophosphate catabolic processGO:00091691580.011
regulation of cellular ketone metabolic processGO:0010565500.011
regulation of mrna splicing via spliceosomeGO:0048024320.011
negative regulation of cell deathGO:00605483450.011
macroautophagyGO:0016236390.011
regulation of viral processGO:00507921030.011
negative regulation of cellular protein metabolic processGO:00322693530.011
multicellular organismal homeostasisGO:0048871670.011
epidermis morphogenesisGO:004873030.010
immune responseGO:00069553070.010
regulation of autophagyGO:0010506520.010
rrna metabolic processGO:0016072400.010
positive regulation of cellular amino acid metabolic processGO:004576430.010
atp metabolic processGO:00460341760.010
ras protein signal transductionGO:0007265730.010
sleepGO:003043120.010
ubiquitin dependent protein catabolic processGO:00065112060.010

UPF1 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
cancerDOID:1621670.084
organ system cancerDOID:00506861640.084
disease of cellular proliferationDOID:145661740.084
nervous system diseaseDOID:8634310.061
neurodegenerative diseaseDOID:12891020.061
central nervous system diseaseDOID:3311860.061