Homo sapiens

31 known processes

UPF2

UPF2 regulator of nonsense transcripts homolog (yeast)

(Aliases: DKFZp434D222,KIAA1408,smg-3,RENT2,MGC138835,MGC138834,HUPF2)

UPF2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
mrna catabolic processGO:0006402560.999
male genitalia developmentGO:003053910.999
nuclear transcribed mrna catabolic processGO:0000956480.999
rna catabolic processGO:0006401710.999
nuclear transcribed mrna catabolic process nonsense mediated decayGO:0000184230.997
cellular macromolecule catabolic processGO:00442653800.918
intracellular mrna localizationGO:000829810.900
histone mrna catabolic processGO:0071044100.778
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.662
mrna metabolic processGO:00160711750.650
nucleoside phosphate catabolic processGO:19012924120.640
purine nucleotide catabolic processGO:00061954050.631
nucleic acid phosphodiester bond hydrolysisGO:00903051020.480
ribonucleoside catabolic processGO:00424544060.470
organophosphate catabolic processGO:00464344300.455
male sex differentiationGO:0046661250.393
positive regulation of translationGO:0045727350.347
female gamete generationGO:000729220.305
rna phosphodiester bond hydrolysisGO:0090501350.303
purine nucleoside catabolic processGO:00061523980.300
neuromuscular synaptic transmissionGO:000727450.275
enzyme linked receptor protein signaling pathwayGO:00071673030.248
ncrna processingGO:0034470830.244
glycosyl compound catabolic processGO:19016584130.241
microtubule cytoskeleton organizationGO:00002261760.230
regulation of cellular component biogenesisGO:00440872810.223
ribonucleoprotein complex biogenesisGO:00226131160.212
nucleoside catabolic processGO:00091644080.206
purine ribonucleotide catabolic processGO:00091544040.201
multicellular organismal agingGO:001025930.187
purine nucleoside monophosphate metabolic processGO:00091261860.175
reproductive processGO:00224141060.174
ncrna metabolic processGO:00346601080.162
rna localizationGO:0006403410.160
vesicle mediated transportGO:00161923710.158
rna phosphodiester bond hydrolysis exonucleolyticGO:0090503140.148
translationGO:00064121320.146
ribonucleoside triphosphate metabolic processGO:00091994120.144
rrna metabolic processGO:0016072400.139
purine nucleoside monophosphate catabolic processGO:00091281580.137
snrna metabolic processGO:0016073150.133
purine ribonucleoside triphosphate catabolic processGO:00092073910.130
nucleoside triphosphate metabolic processGO:00091414220.115
protein ubiquitinationGO:00165673140.110
oocyte differentiationGO:000999420.110
lipid metabolic processGO:00066293810.106
positive regulation of cellular amine metabolic processGO:003324070.106
rna processingGO:00063962550.105
single organism reproductive processGO:0044702980.104
nucleoside triphosphate catabolic processGO:00091433940.102
dna templated transcription initiationGO:0006352350.095
purine containing compound catabolic processGO:00725234110.095
positive regulation of protein complex assemblyGO:0031334860.091
intracellular protein transportGO:00068862700.088
single organism cellular localizationGO:19025803320.087
glycerophospholipid metabolic processGO:0006650840.087
glycerolipid metabolic processGO:00464861070.084
purine nucleoside triphosphate catabolic processGO:00091463920.083
nucleotide catabolic processGO:00091664080.081
purine ribonucleoside metabolic processGO:00461284370.080
regulation of translationGO:0006417890.079
purine ribonucleoside triphosphate metabolic processGO:00092054110.078
mapk cascadeGO:00001652880.075
purine ribonucleoside catabolic processGO:00461303980.075
regulation of protein complex assemblyGO:00432541470.075
lipid modificationGO:0030258840.071
determination of adult lifespanGO:000834020.070
tissue regenerationGO:004224630.067
oogenesisGO:004847720.065
positive regulation of cellular component organizationGO:00511303760.065
microtubule based processGO:00070172100.064
transcription initiation from rna polymerase ii promoterGO:0006367270.063
dna repairGO:00062811980.063
reproductive system developmentGO:0061458560.062
regulation of meiosisGO:004002030.061
positive regulation of phosphorylationGO:00423273940.061
cellular ketone metabolic processGO:0042180800.060
cellular response to dna damage stimulusGO:00069743790.060
dosage compensationGO:000754930.059
ncrna catabolic processGO:0034661140.059
ribonucleoprotein complex assemblyGO:0022618780.059
purine ribonucleoside monophosphate catabolic processGO:00091691580.058
regulation of cellular amino acid metabolic processGO:000652160.058
protein localization to organelleGO:00333652800.057
reproductive structure developmentGO:0048608550.056
endomembrane system organizationGO:00102561960.054
negative regulation of posttranscriptional gene silencingGO:006014930.054
cytokinesisGO:0000910960.054
post embryonic developmentGO:000979120.053
peptidyl serine modificationGO:00182091060.052
atp catabolic processGO:00062001570.052
cellular lipid metabolic processGO:00442553030.051
ribonucleoside triphosphate catabolic processGO:00092033910.050
positive regulation of cellular component biogenesisGO:00440891580.050
sex differentiationGO:0007548450.049
cell cell signalingGO:00072671550.048
positive regulation of cellular amino acid metabolic processGO:004576430.048
nucleoside monophosphate metabolic processGO:00091231910.047
phosphatidylinositol phosphorylationGO:0046854240.046
phospholipid metabolic processGO:0006644990.046
regulation of growthGO:00400081650.045
cell morphogenesisGO:00009022960.045
gonad developmentGO:0008406340.044
regulation of cell differentiationGO:00455953930.044
regulation of protein localizationGO:00328802960.044
embryonic epithelial tube formationGO:000183840.044
blastoderm segmentationGO:000735020.043
regulation of meiotic cell cycleGO:005144540.042
nucleocytoplasmic transportGO:00069131760.042
protein localization to nucleusGO:00345041360.040
segmentationGO:003528240.040
tripartite regional subdivisionGO:000735120.040
regulation of cell divisionGO:00513021160.040
regulation of cellular ketone metabolic processGO:0010565500.039
positive regulation of catabolic processGO:00098963100.039
modification dependent macromolecule catabolic processGO:00436322120.039
cellular response to endogenous stimulusGO:00714953360.039
positive regulation of cellular catabolic processGO:00313312840.039
covalent chromatin modificationGO:00165692540.038
double strand break repairGO:00063021010.038
neuromuscular junction developmentGO:000752830.038
defense responseGO:00069523150.037
regulation of cell maturationGO:190342930.037
posttranscriptional regulation of gene expressionGO:00106082130.037
embryonic morphogenesisGO:0048598850.037
mitotic cell cycleGO:00002783260.037
dephosphorylationGO:00163112090.036
ribonucleotide catabolic processGO:00092614050.036
chromatin organizationGO:00063253510.035
cellular response to oxygen containing compoundGO:19017012760.035
embryo developmentGO:00097901230.034
cell projection organizationGO:00300302520.034
locomotory behaviorGO:000762610.033
developmental process involved in reproductionGO:0003006660.033
protein autophosphorylationGO:00467771230.033
synaptic transmissionGO:0007268610.033
embryo development ending in birth or egg hatchingGO:0009792340.033
primary mirna processingGO:003105330.033
regulation of cell developmentGO:00602841610.032
organelle fissionGO:00482851490.032
cell developmentGO:00484683280.031
regulation of nuclear divisionGO:0051783650.031
agingGO:0007568660.031
long term memoryGO:000761620.031
nucleoside monophosphate catabolic processGO:00091251590.031
ribonucleoside monophosphate metabolic processGO:00091611870.031
regulation of mrna processingGO:0050684480.030
growthGO:00400072020.030
cellular amine metabolic processGO:0044106410.030
regulation of dna repairGO:0006282470.030
cytoplasmic transportGO:00164823790.030
regulation of dephosphorylationGO:0035303960.029
protein modification by small protein conjugationGO:00324463420.028
regulation of cell cycleGO:00517263930.028
purine nucleoside triphosphate metabolic processGO:00091444120.028
oocyte developmentGO:004859910.028
ribosome biogenesisGO:0042254480.027
rna splicingGO:00083801310.027
regulation of protein transportGO:00512232130.026
regulation of small gtpase mediated signal transductionGO:00510561560.025
cellular amino acid metabolic processGO:00065201160.025
snrna transcription from rna polymerase ii promoterGO:004279570.025
positive regulation of transcription initiation from rna polymerase ii promoterGO:006026140.025
protein maturationGO:00516042330.024
nervous system developmentGO:00073992930.024
histone methylationGO:0016571600.023
cellular component morphogenesisGO:00329893140.023
atp metabolic processGO:00460341760.023
organelle assemblyGO:00709251760.023
nuclear divisionGO:00002801280.023
anterior posterior axis specification embryoGO:000859520.022
small gtpase mediated signal transductionGO:0007264780.022
immune responseGO:00069553070.022
regulation of anatomical structure morphogenesisGO:00226032860.022
negative regulation of gene silencing by rnaGO:006096730.022
positive regulation of cell divisionGO:0051781590.022
response to radiationGO:00093141510.021
anatomical structure homeostasisGO:00602491000.021
cell growthGO:00160491600.021
negative regulation of programmed cell deathGO:00430693210.021
ras protein signal transductionGO:0007265730.021
erk1 and erk2 cascadeGO:00703711040.021
cell cycle phase transitionGO:00447701730.021
cell part morphogenesisGO:00329901370.020
regulation of dna metabolic processGO:00510521530.020
response to biotic stimulusGO:00096072760.020
chromatin modificationGO:00165682980.020
nuclear transportGO:00511691790.020
positive regulation of protein phosphorylationGO:00019343130.020
regulation of establishment of protein localizationGO:00702012420.020
regulation of gene expression epigeneticGO:0040029730.019
circulatory system developmentGO:00723592620.019
negative regulation of hydrolase activityGO:00513461820.019
regenerationGO:003109940.019
cell adhesionGO:00071553250.019
negative regulation of cellular component organizationGO:00511292350.019
actin filament based processGO:00300292240.019
purine ribonucleoside monophosphate metabolic processGO:00091671860.019
response to abiotic stimulusGO:00096283360.018
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.018
dna recombinationGO:0006310770.018
regulation of intracellular transportGO:00323861950.018
stem cell divisionGO:001714520.018
cellular macromolecular complex assemblyGO:00346223240.018
cellular protein complex disassemblyGO:0043624360.017
establishment of organelle localizationGO:0051656590.017
reproductionGO:0000003630.017
macromolecule methylationGO:0043414970.017
organ morphogenesisGO:00098871470.017
anterior posterior axis specificationGO:000994820.017
regulation of cellular amine metabolic processGO:0033238110.017
amine metabolic processGO:0009308440.017
regulation of bindingGO:00510981110.017
positive regulation of organelle organizationGO:00106381950.017
response to oxygen containing compoundGO:19017003690.017
cut metabolic processGO:007104330.017
histone modificationGO:00165702510.016
protein targetingGO:00066051870.016
cell activationGO:00017752130.016
response to fungusGO:000962040.016
positive regulation of histone modificationGO:0031058290.016
mitotic cell cycle processGO:19030472860.016
signal transduction by phosphorylationGO:00230142970.015
positive regulation of insulin like growth factor receptor signaling pathwayGO:004356840.015
head developmentGO:00603221080.015
regulation of purine nucleotide metabolic processGO:19005422640.015
cellular response to nitrogen compoundGO:19016991440.015
phosphatidylinositol metabolic processGO:0046488530.015
regulation of nucleotide metabolic processGO:00061402690.015
mitotic cell cycle phase transitionGO:00447721620.015
gtp metabolic processGO:00460392390.015
maturation of ssu rrnaGO:003049030.015
regulation of transcription initiation from rna polymerase ii promoterGO:006026080.015
meiosis iGO:000712740.015
histone lysine methylationGO:0034968500.015
negative regulation of cellular protein metabolic processGO:00322693530.014
neurological system processGO:00508771630.014
double strand break repair via homologous recombinationGO:0000724500.014
regulation of cytoskeleton organizationGO:00514931770.014
behaviorGO:00076101120.014
positive regulation of cell proliferationGO:00082843010.014
tube morphogenesisGO:0035239950.014
neuronal action potentialGO:001922890.014
positive regulation of programmed cell deathGO:00430682490.014
protein methylationGO:0006479740.014
regulation of purine nucleotide catabolic processGO:00331212050.014
positive regulation of transportGO:00510503360.014
regulation of cellular response to stressGO:00801352440.014
regulation of nucleoside metabolic processGO:00091182090.014
response to external biotic stimulusGO:00432072610.013
regulation of cell growthGO:00015581350.013
organelle localizationGO:0051640840.013
regulation of cell cycle processGO:00105642660.013
negative regulation of phosphate metabolic processGO:00459362670.013
response to woundingGO:00096111680.013
protein importGO:00170381300.013
defense response to other organismGO:00985421290.013
centrosome organizationGO:0051297580.013
synapse organizationGO:0050808140.013
histone ubiquitinationGO:0016574310.013
regulation of protein catabolic processGO:00421761550.013
chordate embryonic developmentGO:0043009340.012
regulation of cell morphogenesisGO:00226041530.012
nuclear transcribed mrna catabolic process deadenylation dependent decayGO:0000288140.012
positive regulation of erk1 and erk2 cascadeGO:0070374750.012
neurogenesisGO:00220081690.012
guanosine containing compound catabolic processGO:19010692390.012
regulation of intracellular protein transportGO:00331571230.012
rrna processingGO:0006364350.012
gtp catabolic processGO:00061842370.012
dna catabolic processGO:0006308490.012
spermatid differentiationGO:004851540.012
negative regulation of phosphorus metabolic processGO:00105632670.012
establishment of rna localizationGO:0051236390.012
defense response to fungusGO:005083240.012
nuclear importGO:00511701060.012
positive regulation of cell cycle processGO:00900681060.012
multi organism reproductive processGO:0044703540.012
recombinational repairGO:0000725500.011
negative regulation of immune system processGO:00026831360.011
matingGO:000761810.011
regulation of proteolysisGO:00301622930.011
response to nitrogen compoundGO:19016981840.011
exonucleolytic nuclear transcribed mrna catabolic process involved in deadenylation dependent decayGO:004392860.011
mitotic spindle elongationGO:000002240.011
protein catabolic processGO:00301633250.011
proteolysis involved in cellular protein catabolic processGO:00516032440.011
epidermal growth factor receptor signaling pathwayGO:0007173390.011
transmission of nerve impulseGO:0019226110.011
mrna processingGO:00063971330.011
positive regulation of protein transportGO:00512221350.011
regulation of ras protein signal transductionGO:00465781550.011
regulation of protein maturationGO:19033171500.011
morphogenesis of embryonic epitheliumGO:001633140.011
negative regulation of multicellular organismal processGO:00512413170.011
positive regulation of growthGO:0045927580.011
adult locomotory behaviorGO:000834410.011
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.011
cell projection morphogenesisGO:00488581290.011
synaptic vesicle transportGO:004848950.011
rna polyadenylationGO:0043631140.011
regulation of multi organism processGO:00439001570.011
positive regulation of purine nucleotide metabolic processGO:19005442270.011
regulation of kinase activityGO:00435493140.010
response to other organismGO:00517072610.010
developmental growthGO:0048589480.010
negative regulation of growthGO:0045926970.010
regulation of nervous system developmentGO:0051960880.010
protein complex disassemblyGO:0043241520.010
rna 3 end processingGO:0031123350.010
deadenylation dependent decapping of nuclear transcribed mrnaGO:000029010.010
positive regulation of apoptotic processGO:00430652460.010
actin filament organizationGO:00070151280.010
regulation of response to external stimulusGO:00321012220.010
regulation of neurogenesisGO:0050767820.010
skeletal system developmentGO:0001501790.010
single organism nuclear importGO:19025931040.010
endothelial cell migrationGO:0043542860.010
spindle elongationGO:005123140.010
microtubule organizing center organizationGO:0031023620.010
positive regulation of gtpase activityGO:00435471660.010
rna interferenceGO:001624640.010

UPF2 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:8634310.018
central nervous system diseaseDOID:3311860.018
neurodegenerative diseaseDOID:12891020.018
disease of cellular proliferationDOID:145661740.012