Homo sapiens

5 known processes

COMT

catechol-O-methyltransferase

COMT biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cofactor metabolic processGO:0051186870.111
oxidation reduction processGO:00551143960.106
post embryonic developmentGO:000979120.104
cellular amino acid metabolic processGO:00065201160.102
ribonucleotide catabolic processGO:00092614050.086
lipid metabolic processGO:00066293810.073
purine ribonucleoside metabolic processGO:00461284370.064
cellular lipid metabolic processGO:00442553030.061
glycosyl compound catabolic processGO:19016584130.059
cellular ketone metabolic processGO:0042180800.057
single organism cellular localizationGO:19025803320.051
transmembrane transportGO:00550853990.051
nitrogen compound transportGO:00717051910.049
purine nucleotide catabolic processGO:00061954050.048
purine ribonucleoside triphosphate metabolic processGO:00092054110.048
purine nucleoside catabolic processGO:00061523980.047
amine metabolic processGO:0009308440.045
regulation of cellular amino acid metabolic processGO:000652160.044
cellular amine metabolic processGO:0044106410.044
cytoplasmic transportGO:00164823790.043
gtp catabolic processGO:00061842370.043
oogenesisGO:004847720.041
ribonucleoside catabolic processGO:00424544060.040
ribonucleoside triphosphate metabolic processGO:00091994120.040
oocyte differentiationGO:000999420.039
regulation of cellular ketone metabolic processGO:0010565500.039
response to oxygen containing compoundGO:19017003690.038
purine nucleoside triphosphate catabolic processGO:00091463920.037
determination of adult lifespanGO:000834020.036
regulation of purine nucleotide metabolic processGO:19005422640.036
nucleoside phosphate catabolic processGO:19012924120.036
regulation of nucleotide metabolic processGO:00061402690.036
positive regulation of transportGO:00510503360.035
gtp metabolic processGO:00460392390.034
regulation of cellular amine metabolic processGO:0033238110.034
regulation of kinase activityGO:00435493140.033
nucleoside catabolic processGO:00091644080.033
purine ribonucleoside triphosphate catabolic processGO:00092073910.033
purine containing compound catabolic processGO:00725234110.033
regulation of transferase activityGO:00513383550.033
ribonucleoside triphosphate catabolic processGO:00092033910.033
organic hydroxy compound metabolic processGO:19016151470.032
Mouse
cellular response to dna damage stimulusGO:00069743790.032
negative regulation of multicellular organismal processGO:00512413170.032
purine ribonucleotide catabolic processGO:00091544040.031
female gamete generationGO:000729220.031
system processGO:00030083490.031
intracellular protein transportGO:00068862700.031
response to biotic stimulusGO:00096072760.031
biological adhesionGO:00226103310.030
positive regulation of cellular amine metabolic processGO:003324070.030
organonitrogen compound biosynthetic processGO:19015662000.030
regulation of nucleoside metabolic processGO:00091182090.030
purine nucleoside triphosphate metabolic processGO:00091444120.030
actin filament based processGO:00300292240.030
nucleoside triphosphate catabolic processGO:00091433940.029
negative regulation of phosphate metabolic processGO:00459362670.029
multicellular organismal agingGO:001025930.029
apoptotic signaling pathwayGO:00971902680.029
guanosine containing compound catabolic processGO:19010692390.029
positive regulation of hydrolase activityGO:00513453310.029
ras protein signal transductionGO:0007265730.029
ion transmembrane transportGO:00342203380.029
positive regulation of purine nucleotide catabolic processGO:00331231850.028
regulation of gtp catabolic processGO:00331241800.028
negative regulation of protein metabolic processGO:00512483910.028
negative regulation of catalytic activityGO:00430863350.028
regulation of i kappab kinase nf kappab signalingGO:00431221620.028
negative regulation of cellular protein metabolic processGO:00322693530.028
nucleoside triphosphate metabolic processGO:00091414220.028
positive regulation of cellular amino acid metabolic processGO:004576430.027
regulation of gtpase activityGO:00430871800.027
positive regulation of nucleotide catabolic processGO:00308131850.027
cellular macromolecule catabolic processGO:00442653800.026
positive regulation of gtp catabolic processGO:00331261660.026
negative regulation of phosphorus metabolic processGO:00105632670.026
positive regulation of protein phosphorylationGO:00019343130.026
vesicle mediated transportGO:00161923710.026
regulation of cellular component biogenesisGO:00440872810.025
protein localization to organelleGO:00333652800.025
regenerationGO:003109940.025
nucleotide catabolic processGO:00091664080.024
single organism membrane organizationGO:00448022680.024
purine ribonucleoside catabolic processGO:00461303980.024
guanosine containing compound metabolic processGO:19010682440.024
regulation of purine nucleotide catabolic processGO:00331212050.024
monocarboxylic acid metabolic processGO:00327871850.024
endomembrane system organizationGO:00102561960.024
cell morphogenesisGO:00009022960.023
small gtpase mediated signal transductionGO:0007264780.023
response to abiotic stimulusGO:00096283360.023
positive regulation of nucleoside metabolic processGO:00459791860.023
carboxylic acid biosynthetic processGO:0046394970.023
positive regulation of cellular catabolic processGO:00313312840.023
cellular component morphogenesisGO:00329893140.023
positive regulation of catabolic processGO:00098963100.023
positive regulation of purine nucleotide metabolic processGO:19005442270.023
cell developmentGO:00484683280.022
response to external biotic stimulusGO:00432072610.022
mitotic cell cycleGO:00002783260.022
positive regulation of cellular component organizationGO:00511303760.022
positive regulation of phosphorylationGO:00423273940.022
spermatid developmentGO:000728640.022
organophosphate catabolic processGO:00464344300.022
epithelium developmentGO:00604292270.022
protein oligomerizationGO:00512591730.022
regulation of protein kinase activityGO:00458592890.021
regulation of protein transportGO:00512232130.021
cellular response to oxygen containing compoundGO:19017012760.021
negative regulation of intracellular signal transductionGO:19025321830.021
striated muscle contractionGO:0006941520.021
oocyte developmentGO:004859910.021
lipid biosynthetic processGO:00086101770.021
inorganic ion transmembrane transportGO:00986602310.021
response to molecule of bacterial originGO:0002237820.021
cytokine productionGO:00018162470.021
regulation of nucleotide catabolic processGO:00308112050.020
immune responseGO:00069553070.020
cation transportGO:00068123310.020
carbohydrate derivative biosynthetic processGO:19011372070.020
organophosphate biosynthetic processGO:00904071630.020
organic acid biosynthetic processGO:0016053970.020
response to woundingGO:00096111680.020
locomotory behaviorGO:000762610.020
memoryGO:000761330.020
regulation of cytokine productionGO:00018172320.020
negative regulation of hydrolase activityGO:00513461820.019
regulation of intracellular transportGO:00323861950.019
negative regulation of protein modification processGO:00314002000.019
signal transduction by phosphorylationGO:00230142970.019
lipid catabolic processGO:0016042840.019
protein maturationGO:00516042330.019
regulation of cell cycleGO:00517263930.019
carbohydrate metabolic processGO:00059752070.019
response to cytokineGO:00340972320.019
anion transportGO:00068201610.019
innate immune responseGO:00450871780.018
single organism carbohydrate metabolic processGO:00447231930.018
cell projection organizationGO:00300302520.018
segmentationGO:003528240.018
circulatory system developmentGO:00723592620.018
nervous system developmentGO:00073992930.018
regulation of establishment of protein localizationGO:00702012420.018
positive regulation of i kappab kinase nf kappab signalingGO:00431231320.018
membrane organizationGO:00610242920.018
protein processingGO:00164852260.018
response to other organismGO:00517072610.018
organic anion transportGO:00157111030.018
intrinsic apoptotic signaling pathwayGO:00971931270.018
mapk cascadeGO:00001652880.017
positive regulation of nucleotide metabolic processGO:00459812300.017
cell adhesionGO:00071553250.017
regulation of protein serine threonine kinase activityGO:00719001790.017
regulation of secretion by cellGO:19035301770.017
microtubule based processGO:00070172100.017
regulation of microtubule cytoskeleton organizationGO:0070507610.017
regulation of protein localizationGO:00328802960.017
inorganic cation transmembrane transportGO:00986621940.017
adult locomotory behaviorGO:000834410.017
negative regulation of cell cycleGO:00457861930.017
cell activationGO:00017752130.017
cellular protein catabolic processGO:00442572610.017
positive regulation of kinase activityGO:00336742040.017
spermatid differentiationGO:004851540.017
endocytosisGO:00068971590.017
secretion by cellGO:00329402260.017
peripheral nervous system developmentGO:000742220.017
negative regulation of apoptotic processGO:00430663160.017
posttranscriptional regulation of gene expressionGO:00106082130.017
negative regulation of cell deathGO:00605483450.017
regulation of cellular component movementGO:00512703340.016
small molecule biosynthetic processGO:00442831570.016
carboxylic acid catabolic processGO:0046395710.016
cation transmembrane transportGO:00986552380.016
secretionGO:00469032540.016
regulation of multi organism processGO:00439001570.016
cardiovascular system developmentGO:00723582620.016
protein catabolic processGO:00301633250.016
cardiac muscle cell contractionGO:008600340.016
negative regulation of phosphorylationGO:00423261740.016
positive regulation of protein kinase activityGO:00458601900.016
neurological system processGO:00508771630.016
chemical homeostasisGO:00488783060.016
mitochondrion organizationGO:00070051560.016
response to organic cyclic compoundGO:00140702040.016
negative regulation of transferase activityGO:00513481240.016
defense responseGO:00069523150.016
metal ion transportGO:00300012720.015
regulation of response to external stimulusGO:00321012220.015
i kappab kinase nf kappab signalingGO:00072491660.015
stem cell divisionGO:001714520.015
negative regulation of cellular component organizationGO:00511292350.015
response to nitrogen compoundGO:19016981840.015
wound healingGO:00420601150.015
enzyme linked receptor protein signaling pathwayGO:00071673030.015
ubiquitin dependent protein catabolic processGO:00065112060.015
cellular lipid catabolic processGO:0044242650.015
positive regulation of immune system processGO:00026842830.015
g protein coupled receptor signaling pathwayGO:00071862070.015
blastoderm segmentationGO:000735020.015
negative regulation of posttranscriptional gene silencingGO:006014930.015
hindbrain developmentGO:003090230.015
growthGO:00400072020.015
protein targetingGO:00066051870.015
plasma membrane organizationGO:00070091150.015
neuromuscular junction developmentGO:000752830.014
positive regulation of apoptotic processGO:00430652460.014
muscle contractionGO:0006936730.014
protein localization to membraneGO:00726571600.014
small molecule catabolic processGO:0044282920.014
protein ubiquitinationGO:00165673140.014
protein modification by small protein conjugationGO:00324463420.014
organic acid catabolic processGO:0016054710.014
response to metal ionGO:0010038840.014
regulation of cell cycle processGO:00105642660.014
coenzyme metabolic processGO:0006732650.014
positive regulation of gtpase activityGO:00435471660.014
blood vessel developmentGO:00015681720.014
regulation of body fluid levelsGO:0050878990.014
regulation of vesicle mediated transportGO:00606271300.014
response to bacteriumGO:00096171440.014
positive regulation of developmental processGO:00510943140.014
anatomical structure formation involved in morphogenesisGO:00486462840.014
cellular response to cytokine stimulusGO:00713451810.014
proteasomal protein catabolic processGO:00104981760.013
positive regulation of cell deathGO:00109422630.013
negative regulation of gene silencing by rnaGO:006096730.013
positive regulation of cellular component biogenesisGO:00440891580.013
embryo developmentGO:00097901230.013
regulation of feeding behaviorGO:006025930.013
fatty acid metabolic processGO:00066311150.013
microtubule cytoskeleton organizationGO:00002261760.013
peptidyl tyrosine modificationGO:00182121700.013
modification dependent protein catabolic processGO:00199412090.013
multi organism cellular processGO:00447641560.013
muscle system processGO:0003012810.013
negative regulation of gene silencing by mirnaGO:006096530.013
regulation of proteolysisGO:00301622930.013
metencephalon developmentGO:002203720.013
regulation of cytoskeleton organizationGO:00514931770.013
negative regulation of programmed cell deathGO:00430693210.013
cytokine mediated signaling pathwayGO:00192211090.013
organic acid transportGO:0015849650.013
sulfur compound metabolic processGO:00067901010.013
interspecies interaction between organismsGO:00444191560.013
negative regulation of transportGO:00510511760.013
maintenance of locationGO:00512351120.013
mitotic cell cycle processGO:19030472860.013
tissue regenerationGO:004224630.013
cellular modified amino acid metabolic processGO:0006575640.013
meiosis iGO:000712740.013
cell growthGO:00160491600.013
negative regulation of cell proliferationGO:00082852280.012
regulation of cell morphogenesisGO:00226041530.012
nuclear transportGO:00511691790.012
regulation of cell differentiationGO:00455953930.012
proteolysis involved in cellular protein catabolic processGO:00516032440.012
positive regulation of secretion by cellGO:19035321080.012
blood vessel morphogenesisGO:00485141620.012
angiogenesisGO:00015251470.012
regulation of locomotionGO:00400123290.012
negative regulation of cellular amino acid metabolic processGO:004576320.012
steroid metabolic processGO:0008202940.012
regulation of ras protein signal transductionGO:00465781550.012
negative regulation of developmental processGO:00510932470.012
protein localization to nucleusGO:00345041360.012
cellular cation homeostasisGO:00300031630.012
cellular macromolecular complex assemblyGO:00346223240.012
regulation of protein complex assemblyGO:00432541470.012
regulation of response to woundingGO:19030341010.012
regulation of growthGO:00400081650.012
cell part morphogenesisGO:00329901370.012
mitochondrial transportGO:0006839600.012
cardiac muscle contractionGO:0060048340.012
cation homeostasisGO:00550801890.012
protein localization to plasma membraneGO:0072659930.012
single organism reproductive processGO:0044702980.012
nuclear importGO:00511701060.012
ion homeostasisGO:00508012300.012
coagulationGO:0050817780.012
negative regulation of protein phosphorylationGO:00019331400.012
regulation of sequence specific dna binding transcription factor activityGO:00510902110.012
positive regulation of programmed cell deathGO:00430682490.012
response to organonitrogen compoundGO:00102431560.012
regulation of mapk cascadeGO:00434082620.012
nucleocytoplasmic transportGO:00069131760.012
dephosphorylationGO:00163112090.012
sensory perception of painGO:001923340.012
response to virusGO:00096151260.012
glycerophospholipid metabolic processGO:0006650840.012
endosomal transportGO:00161971290.012
positive regulation of secretionGO:00510471160.012
divalent inorganic cation transportGO:00725111580.012
regulation of anatomical structure morphogenesisGO:00226032860.012
endothelial cell migrationGO:0043542860.012
regulation of cell adhesionGO:00301551660.012
organelle assemblyGO:00709251760.011
regulation of secretionGO:00510461940.011
positive regulation of transferase activityGO:00513472270.011
anterior posterior axis specificationGO:000994820.011
viral life cycleGO:00190581320.011
regulation of cytoplasmic transportGO:19036491490.011
visual behaviorGO:000763220.011
regulation of neural precursor cell proliferationGO:200017740.011
regulation of wnt signaling pathwayGO:00301111230.011
regulation of immune responseGO:00507762010.011
negative regulation of kinase activityGO:00336731060.011
regulation of cellular response to stressGO:00801352440.011
regulation of protein catabolic processGO:00421761550.011
viral processGO:00160321460.011
cell divisionGO:00513011680.011
cellular ion homeostasisGO:00068731680.011
modification dependent macromolecule catabolic processGO:00436322120.011
regulation of mitotic cell cycle phase transitionGO:19019901180.011
regulation of ion transportGO:00432691890.011
protein homooligomerizationGO:00512601000.011
glycoprotein metabolic processGO:00091001100.011
neurogenesisGO:00220081690.011
protein importGO:00170381300.011
negative regulation of cellular amine metabolic processGO:003323930.011
lipid localizationGO:00108761060.011
regulation of transmembrane transportGO:00347621390.011
response to lipidGO:00339932060.011
purine nucleoside monophosphate metabolic processGO:00091261860.011
positive regulation of protein complex assemblyGO:0031334860.011
cellular homeostasisGO:00197251960.011
vasodilationGO:004231140.011
regulation of protein maturationGO:19033171500.011
actin cytoskeleton organizationGO:00300362070.011
metal ion homeostasisGO:00550651690.011
establishment of protein localization to membraneGO:00901501210.011
regulation of cell developmentGO:00602841610.011
neuroblast divisionGO:005505710.011
divalent metal ion transportGO:00708381520.011
behaviorGO:00076101120.011
negative regulation of synaptic transmissionGO:005080520.011
cerebellum developmentGO:002154920.011
regulation of muscle system processGO:0090257530.011
nucleic acid phosphodiester bond hydrolysisGO:00903051020.011
generation of neuronsGO:00486991520.011
response to inorganic substanceGO:00100351270.011
response to oxygen levelsGO:00704821000.011
cellular response to lipidGO:00713961270.011
regulation of small gtpase mediated signal transductionGO:00510561560.011
hemostasisGO:0007599760.011
double strand break repairGO:00063021010.011
tripartite regional subdivisionGO:000735120.010
morphogenesis of a polarized epitheliumGO:000173830.010
regulation of protein localization to nucleusGO:1900180850.010
negative regulation of organelle organizationGO:00106391260.010
response to axon injuryGO:004867810.010
membrane lipid metabolic processGO:0006643530.010
regulation of cell growthGO:00015581350.010
rna processingGO:00063962550.010
tissue migrationGO:00901301190.010
epithelial cell migrationGO:00106311190.010
chromatin organizationGO:00063253510.010
regulation of protein stabilityGO:0031647870.010
salivary gland morphogenesisGO:000743540.010
glycerolipid metabolic processGO:00464861070.010
negative regulation of mitotic cell cycleGO:00459301020.010
calcium ion transportGO:00068161470.010
regulation of actin filament based processGO:00329701410.010
regulation of endocytosisGO:0030100720.010
regulation of intracellular protein transportGO:00331571230.010
peptidyl tyrosine phosphorylationGO:00181081700.010
monocarboxylic acid biosynthetic processGO:0072330670.010
anterior posterior axis specification embryoGO:000859520.010
lipid transportGO:0006869900.010
cell projection morphogenesisGO:00488581290.010
response to radiationGO:00093141510.010
glycoprotein biosynthetic processGO:0009101910.010
regulation of ion transmembrane transportGO:00347651320.010
regulation of cell motilityGO:20001452990.010
negative regulation of mitotic cell cycle phase transitionGO:1901991850.010
regulation of stress activated mapk cascadeGO:0032872840.010
regulation of apoptotic signaling pathwayGO:20012331750.010

COMT disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:00146672950.073
inherited metabolic disorderDOID:6552420.059
central nervous system diseaseDOID:3311860.029
nervous system diseaseDOID:8634310.029
neurodegenerative diseaseDOID:12891020.019
cancerDOID:1621670.018
disease of cellular proliferationDOID:145661740.018
sensory system diseaseDOID:00501552030.018
organ system cancerDOID:00506861640.016
immune system diseaseDOID:29141550.014
musculoskeletal system diseaseDOID:172230.013
amino acid metabolic disorderDOID:9252500.013
neuropathyDOID:870520.012
eye and adnexa diseaseDOID:14921500.011
eye diseaseDOID:56141490.011
retinal diseaseDOID:56791180.011
disease of mental healthDOID:150700.007
cognitive disorderDOID:1561290.002
psychotic disorderDOID:246880.001
schizophreniaDOID:541980.001