Homo sapiens

96 known processes

TARDBP

TAR DNA binding protein

(Aliases: TDP-43,ALS10)

TARDBP biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
rna processingGO:00063962550.995
female gamete generationGO:000729220.976
posttranscriptional regulation of gene expressionGO:00106082130.954
post embryonic developmentGO:000979120.934
translationGO:00064121320.890
oogenesisGO:004847720.857
regulation of mrna splicing via spliceosomeGO:0048024320.745
embryo developmentGO:00097901230.736
mrna metabolic processGO:00160711750.731
mrna processingGO:00063971330.702
posttranscriptional gene silencing by rnaGO:0035194250.701
determination of adult lifespanGO:000834020.683
cellular macromolecule catabolic processGO:00442653800.593
regulation of alternative mrna splicing via spliceosomeGO:0000381220.572
oocyte developmentGO:004859910.556
multicellular organismal agingGO:001025930.551
negative regulation of gene silencing by rnaGO:006096730.533
ribonucleoprotein complex biogenesisGO:00226131160.514
cell developmentGO:00484683280.513
Zebrafish Fly
rna catabolic processGO:0006401710.501
spermatid developmentGO:000728640.483
regulation of rna splicingGO:0043484620.475
posttranscriptional gene silencingGO:0016441250.386
regulation of meiotic cell cycleGO:005144540.368
intracellular mrna localizationGO:000829810.367
oocyte differentiationGO:000999420.343
negative regulation of developmental processGO:00510932470.338
Fly
regulation of rna stabilityGO:0043487230.333
response to abiotic stimulusGO:00096283360.330
negative regulation of posttranscriptional gene silencingGO:006014930.329
regulation of meiosisGO:004002030.328
negative regulation of cell differentiationGO:00455961710.320
regulation of translationGO:0006417890.314
ribonucleoside monophosphate metabolic processGO:00091611870.311
nucleobase containing compound transportGO:0015931510.311
embryo development ending in birth or egg hatchingGO:0009792340.306
nucleic acid transportGO:0050657390.305
regulation of mrna metabolic processGO:1903311530.304
negative regulation of cellular protein metabolic processGO:00322693530.301
establishment of rna localizationGO:0051236390.300
crd mediated mrna stabilizationGO:007093450.290
mitotic cell cycle processGO:19030472860.276
reproductionGO:0000003630.272
alternative mrna splicing via spliceosomeGO:0000380270.258
negative regulation of rna splicingGO:0033119150.249
histone methylationGO:0016571600.241
nuclear divisionGO:00002801280.239
circadian regulation of translationGO:009716710.228
regulation of growthGO:00400081650.226
Fly
rna localizationGO:0006403410.197
regulation of cell cycleGO:00517263930.191
mitotic cell cycleGO:00002783260.185
mrna splicing via spliceosomeGO:0000398890.182
gene silencing by rnaGO:0031047260.179
rna splicing via transesterification reactionsGO:0000375900.176
ribonucleoprotein complex assemblyGO:0022618780.176
reproductive processGO:00224141060.170
positive regulation of cell proliferationGO:00082843010.168
stem cell differentiationGO:0048863930.164
rna interferenceGO:001624640.155
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377890.154
spermatid differentiationGO:004851540.151
regulation of gene expression epigeneticGO:0040029730.148
neurogenesisGO:00220081690.147
Zebrafish Fly
nuclear exportGO:0051168690.144
stem cell developmentGO:0048864690.132
regulation of cell cycle processGO:00105642660.127
growthGO:00400072020.118
Zebrafish Fly
nuclear transcribed mrna catabolic process nonsense mediated decayGO:0000184230.116
single organism cellular localizationGO:19025803320.115
rna splicingGO:00083801310.114
ribonucleoprotein complex subunit organizationGO:0071826810.108
cytoplasmic transportGO:00164823790.108
regulation of mrna processingGO:0050684480.096
methylationGO:00322591060.093
positive regulation of developmental processGO:00510943140.091
regionalizationGO:0003002290.090
behaviorGO:00076101120.089
Zebrafish Fly
nervous system developmentGO:00073992930.088
Zebrafish Fly
glycosyl compound catabolic processGO:19016584130.084
vesicle mediated transportGO:00161923710.082
negative regulation of programmed cell deathGO:00430693210.076
purine nucleoside monophosphate catabolic processGO:00091281580.072
sexual reproductionGO:0019953370.070
response to biotic stimulusGO:00096072760.066
mrna export from nucleusGO:0006406290.066
purine ribonucleoside triphosphate metabolic processGO:00092054110.064
regulation of mrna stabilityGO:0043488230.064
purine ribonucleoside catabolic processGO:00461303980.063
gene silencingGO:0016458490.063
negative regulation of apoptotic processGO:00430663160.063
negative regulation of protein metabolic processGO:00512483910.062
nuclear transcribed mrna catabolic processGO:0000956480.061
segmentationGO:003528240.060
rna transportGO:0050658390.059
protein acylationGO:00435431380.059
lipid localizationGO:00108761060.058
anterior posterior axis specification embryoGO:000859520.055
purine ribonucleoside monophosphate catabolic processGO:00091691580.055
endocytosisGO:00068971590.055
mrna catabolic processGO:0006402560.054
epithelium developmentGO:00604292270.054
single organism reproductive processGO:0044702980.054
cell divisionGO:00513011680.053
organelle assemblyGO:00709251760.053
positive regulation of translationGO:0045727350.052
pattern specification processGO:0007389430.052
rna polyadenylationGO:0043631140.052
hemidesmosome assemblyGO:003158150.052
gene silencing by mirnaGO:0035195230.051
negative regulation of translationGO:0017148370.051
negative regulation of mrna splicing via spliceosomeGO:0048025110.050
stem cell divisionGO:001714520.049
ncrna metabolic processGO:00346601080.048
cellular component morphogenesisGO:00329893140.047
Zebrafish Fly
cell junction organizationGO:0034330790.047
regulation of intrinsic apoptotic signaling pathwayGO:2001242720.046
cellular amine metabolic processGO:0044106410.046
multi organism reproductive processGO:0044703540.045
muscle contractionGO:0006936730.045
chromatin modificationGO:00165682980.045
response to nutrient levelsGO:0031667810.045
viral life cycleGO:00190581320.043
response to external biotic stimulusGO:00432072610.042
rna phosphodiester bond hydrolysisGO:0090501350.042
regulation of cellular response to stressGO:00801352440.041
blastoderm segmentationGO:000735020.041
protein alkylationGO:0008213740.040
histone modificationGO:00165702510.040
regulation of cell divisionGO:00513021160.040
negative regulation of cell deathGO:00605483450.039
nuclear transportGO:00511691790.039
organelle fissionGO:00482851490.039
multicellular organism reproductionGO:0032504420.039
amine metabolic processGO:0009308440.038
nucleoside phosphate catabolic processGO:19012924120.038
osteoblast differentiationGO:0001649920.038
gamete generationGO:0007276250.038
response to oxygen containing compoundGO:19017003690.037
ribonucleoside catabolic processGO:00424544060.037
purine nucleoside monophosphate metabolic processGO:00091261860.037
agingGO:0007568660.036
positive regulation of cellular catabolic processGO:00313312840.036
tripartite regional subdivisionGO:000735120.035
cell junction assemblyGO:0034329670.035
nucleocytoplasmic transportGO:00069131760.032
negative regulation of cell cycle processGO:00109481210.032
apoptotic signaling pathwayGO:00971902680.032
negative regulation of mrna metabolic processGO:1903312150.032
meiotic nuclear divisionGO:0007126100.032
ribonucleoside triphosphate metabolic processGO:00091994120.031
regulation of cell differentiationGO:00455953930.031
microtubule cytoskeleton organizationGO:00002261760.031
negative regulation of epidermal cell differentiationGO:004560540.031
positive regulation of cell activationGO:0050867810.031
positive regulation of dna metabolic processGO:0051054730.030
macromolecule methylationGO:0043414970.030
response to cytokineGO:00340972320.029
regenerationGO:003109940.029
positive regulation of organelle organizationGO:00106381950.029
female sex differentiationGO:0046660120.028
reproductive structure developmentGO:0048608550.028
production of mirnas involved in gene silencing by mirnaGO:0035196120.028
anterior posterior axis specificationGO:000994820.028
protein stabilizationGO:0050821640.028
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.027
nucleoside monophosphate catabolic processGO:00091251590.026
embryonic morphogenesisGO:0048598850.025
multicellular organismal reproductive processGO:0048609400.025
cellular response to oxygen containing compoundGO:19017012760.025
ras protein signal transductionGO:0007265730.025
intrinsic apoptotic signaling pathwayGO:00971931270.025
spliceosomal complex assemblyGO:0000245170.024
atp metabolic processGO:00460341760.024
positive regulation of proteolysisGO:00458621420.024
purine nucleoside catabolic processGO:00061523980.024
cell substrate junction assemblyGO:0007044350.024
spermatogenesisGO:0007283220.024
protein methylationGO:0006479740.024
rna 3 end processingGO:0031123350.023
nucleoside catabolic processGO:00091644080.023
regulation of protein modification by small protein conjugation or removalGO:19033201070.023
positive regulation of chromatin assembly or disassemblyGO:004579920.023
purine nucleotide catabolic processGO:00061954050.023
regulation of nervous system developmentGO:0051960880.023
Fly
negative regulation of cell cycleGO:00457861930.023
regulation of mitotic cell cycleGO:00073461890.023
regulation of endopeptidase activityGO:00525481700.022
nucleic acid phosphodiester bond hydrolysisGO:00903051020.022
signal transduction by p53 class mediatorGO:0072331720.022
cellular process involved in reproduction in multicellular organismGO:0022412150.022
dorsal ventral pattern formationGO:0009953150.022
response to extracellular stimulusGO:0009991850.022
organophosphate catabolic processGO:00464344300.022
cellular macromolecular complex assemblyGO:00346223240.021
response to heatGO:0009408210.021
vasculature developmentGO:00019441810.021
regulation of viral processGO:00507921030.021
interspecies interaction between organismsGO:00444191560.021
positive regulation of transportGO:00510503360.021
nuclear importGO:00511701060.021
regulation of chromatin modificationGO:1903308510.021
rna export from nucleusGO:0006405330.020
regulation of developmental growthGO:0048638300.020
Fly
positive regulation of cellular component organizationGO:00511303760.020
circulatory system developmentGO:00723592620.020
positive regulation of cell cycleGO:00457871400.020
response to starvationGO:0042594590.020
blastocyst developmentGO:000182430.020
response to nitrogen compoundGO:19016981840.020
dna replicationGO:00062601160.019
protein localization to organelleGO:00333652800.019
purine nucleoside triphosphate metabolic processGO:00091444120.019
nitrogen compound transportGO:00717051910.019
purine ribonucleotide catabolic processGO:00091544040.019
purine nucleoside triphosphate catabolic processGO:00091463920.019
negative regulation of peptidase activityGO:0010466910.018
regulation of cell cycle phase transitionGO:19019871260.018
small molecule biosynthetic processGO:00442831570.018
cell growthGO:00160491600.017
Zebrafish
ubiquitin dependent protein catabolic processGO:00065112060.017
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.017
rna phosphodiester bond hydrolysis exonucleolyticGO:0090503140.017
positive regulation of mrna processingGO:0050685170.017
atp catabolic processGO:00062001570.017
regulation of apoptotic signaling pathwayGO:20012331750.017
regulation of translational initiationGO:0006446240.017
regulation of viral genome replicationGO:0045069480.016
cell projection organizationGO:00300302520.016
Zebrafish Fly
immune responseGO:00069553070.016
neuron projection developmentGO:00311751060.016
Zebrafish Fly
regulation of dna metabolic processGO:00510521530.016
angiogenesisGO:00015251470.016
blood vessel morphogenesisGO:00485141620.016
regulation of cysteine type endopeptidase activityGO:20001161270.015
cell cycle checkpointGO:00000751170.015
ribonucleoside monophosphate catabolic processGO:00091581580.015
nucleoside monophosphate metabolic processGO:00091231910.015
generation of neuronsGO:00486991520.015
Zebrafish Fly
developmental process involved in reproductionGO:0003006660.015
regulation of cellular ketone metabolic processGO:0010565500.015
ncrna processingGO:0034470830.014
germ cell developmentGO:000728180.014
tissue regenerationGO:004224630.014
ossificationGO:00015031210.014
dosage compensationGO:000754930.014
response to drugGO:0042493810.014
positive regulation of growthGO:0045927580.014
cell cycle phase transitionGO:00447701730.014
covalent chromatin modificationGO:00165692540.014
positive regulation of immunoglobulin mediated immune responseGO:000289140.014
mrna transportGO:0051028300.013
muscle system processGO:0003012810.013
cellular component disassemblyGO:0022411920.013
chordate embryonic developmentGO:0043009340.013
purine ribonucleoside triphosphate catabolic processGO:00092073910.013
organelle localizationGO:0051640840.013
ribonucleoside triphosphate catabolic processGO:00092033910.013
organ morphogenesisGO:00098871470.013
development of primary sexual characteristicsGO:0045137350.013
regulation of immune effector processGO:0002697910.013
regulation of peptidase activityGO:00525471800.013
cell part morphogenesisGO:00329901370.013
Zebrafish Fly
protein ubiquitinationGO:00165673140.013
heart morphogenesisGO:0003007480.013
response to temperature stimulusGO:0009266220.013
regulation of chromosome organizationGO:00330441030.013
developmental growthGO:0048589480.012
Zebrafish Fly
regulation of lymphocyte activationGO:00512491030.012
microtubule based processGO:00070172100.012
purine ribonucleoside monophosphate metabolic processGO:00091671860.012
regulation of leukocyte mediated immunityGO:0002703380.012
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822290.012
negative regulation of mrna processingGO:0050686120.012
response to lipidGO:00339932060.012
nuclear migrationGO:000709710.012
protein targeting to nucleusGO:00447441040.012
chemotaxisGO:00069351570.012
mrna 3 end processingGO:0031124240.011
negative regulation of multicellular organismal processGO:00512413170.011
Fly
regulation of nuclear divisionGO:0051783650.011
response to interferon gammaGO:0034341390.011
system processGO:00030083490.011
cellular ketone metabolic processGO:0042180800.011
receptor mediated endocytosisGO:0006898840.011
anatomical structure formation involved in morphogenesisGO:00486462840.011
nucleoside triphosphate metabolic processGO:00091414220.011
mitotic sister chromatid segregationGO:0000070530.011
regulation of protein stabilityGO:0031647870.011
defense responseGO:00069523150.011
regulation of protein complex assemblyGO:00432541470.011
ribonucleotide catabolic processGO:00092614050.011
chromatin organizationGO:00063253510.011
dna geometric changeGO:0032392320.010
positive regulation of leukocyte mediated immunityGO:0002705240.010
mitotic cell cycle phase transitionGO:00447721620.010
innate immune responseGO:00450871780.010
cellular amino acid metabolic processGO:00065201160.010
nucleotide catabolic processGO:00091664080.010
regulation of histone modificationGO:0031056470.010
protein maturationGO:00516042330.010
regulation of protein transportGO:00512232130.010
negative regulation of cell growthGO:0030308830.010
regulation of cellular component biogenesisGO:00440872810.010
Fly
sex differentiationGO:0007548450.010

TARDBP disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
myopathyDOID:4231040.875
muscle tissue diseaseDOID:661130.875
musculoskeletal system diseaseDOID:172230.875
muscular diseaseDOID:00800001140.875
muscular dystrophyDOID:9884510.313
nervous system diseaseDOID:8634310.257
neurodegenerative diseaseDOID:12891020.257
central nervous system diseaseDOID:3311860.257
sensory system diseaseDOID:00501552030.081
eye and adnexa diseaseDOID:14921500.081
motor neuron diseaseDOID:231270.002
amyotrophic lateral sclerosisDOID:332200.002