Homo sapiens

0 known processes

AFF4

AF4/FMR2 family, member 4

(Aliases: MCEF,MGC75036,AF5Q31)

AFF4 biological process predictions


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Biological processGO term IDProcess sizeProbabilityFunc Analog Org
positive regulation of dna templated transcription elongationGO:0032786180.998
regulation of transcription elongation from rna polymerase ii promoterGO:0034243130.964
snrna transcriptionGO:000930180.963
regulation of wnt signaling pathway planar cell polarity pathwayGO:200009520.943
positive regulation of transcription elongation from rna polymerase ii promoterGO:0032968100.933
regulation of transcription from rna polymerase iii promoterGO:0006359130.914
regulation of dna templated transcription elongationGO:0032784230.896
dna templated transcription elongationGO:0006354250.878
morphogenesis of a polarized epitheliumGO:000173830.806
negative regulation of phosphatase activityGO:0010923610.787
dephosphorylationGO:00163112090.755
transcription from rna polymerase iii promoterGO:0006383190.721
covalent chromatin modificationGO:00165692540.653
establishment of planar polarityGO:000173630.558
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.521
chromatin modificationGO:00165682980.509
canonical wnt signaling pathwayGO:00600701160.487
establishment of tissue polarityGO:000716430.474
mrna destabilizationGO:006115710.456
regulation of cytoskeleton organizationGO:00514931770.398
regulation of anatomical structure morphogenesisGO:00226032860.385
system processGO:00030083490.378
cell developmentGO:00484683280.364
Mouse
negative regulation of phosphorus metabolic processGO:00105632670.359
transcription elongation from rna polymerase ii promoterGO:0006368180.352
response to abiotic stimulusGO:00096283360.320
negative regulation of hydrolase activityGO:00513461820.307
internal protein amino acid acetylationGO:00064751010.306
regulation of non canonical wnt signaling pathwayGO:200005040.306
snrna transcription from rna polymerase ii promoterGO:004279570.306
mitotic cell cycleGO:00002783260.286
negative regulation of catalytic activityGO:00430863350.273
cell morphogenesisGO:00009022960.272
regulation of phosphatase activityGO:0010921810.266
histone modificationGO:00165702510.252
positive regulation of non canonical wnt signaling pathwayGO:200005230.251
positive regulation of wnt signaling pathway planar cell polarity pathwayGO:200009620.237
regulation of cytoplasmic translationGO:200076520.229
segmentationGO:003528240.221
blastoderm segmentationGO:000735020.218
cellular macromolecule catabolic processGO:00442653800.211
negative regulation of phosphate metabolic processGO:00459362670.199
positive regulation of transcription from rna polymerase iii promoterGO:0045945100.193
negative regulation of canonical wnt signaling pathwayGO:0090090550.193
actin filament based processGO:00300292240.191
regulation of dephosphorylationGO:0035303960.184
regulation of dna templated transcription in response to stressGO:0043620180.157
rna splicingGO:00083801310.157
cellular ketone metabolic processGO:0042180800.144
wnt signaling pathwayGO:00160551560.143
methylationGO:00322591060.130
post embryonic developmentGO:000979120.129
negative regulation of dephosphorylationGO:0035305630.126
amine metabolic processGO:0009308440.124
positive regulation of catabolic processGO:00098963100.119
regulation of response to dna damage stimulusGO:2001020940.117
negative regulation of wnt signaling pathwayGO:0030178690.116
regulation of cellular response to stressGO:00801352440.113
embryo developmentGO:00097901230.113
Human
actin cytoskeleton organizationGO:00300362070.111
negative regulation of protein metabolic processGO:00512483910.111
histone acetylationGO:0016573930.110
regulation of protein kinase activityGO:00458592890.108
ribonucleotide catabolic processGO:00092614050.104
nucleoside phosphate catabolic processGO:19012924120.103
oogenesisGO:004847720.099
cellular component morphogenesisGO:00329893140.098
multicellular organismal agingGO:001025930.096
histone methylationGO:0016571600.096
mapk cascadeGO:00001652880.093
purine containing compound catabolic processGO:00725234110.088
gtp catabolic processGO:00061842370.085
cellular amino acid metabolic processGO:00065201160.083
nucleoside catabolic processGO:00091644080.080
cellular amine metabolic processGO:0044106410.080
regulation of cellular component sizeGO:0032535820.079
oocyte developmentGO:004859910.078
positive regulation of transportGO:00510503360.076
regulation of cell shapeGO:0008360480.076
regulation of cellular amine metabolic processGO:0033238110.075
actin filament organizationGO:00070151280.075
anterior posterior axis specificationGO:000994820.073
determination of adult lifespanGO:000834020.072
purine ribonucleotide catabolic processGO:00091544040.070
positive regulation of cellular amine metabolic processGO:003324070.069
erythrocyte developmentGO:004882130.069
glycosyl compound catabolic processGO:19016584130.067
cellular response to oxygen containing compoundGO:19017012760.067
protein methylationGO:0006479740.066
purine nucleotide catabolic processGO:00061954050.066
guanosine containing compound catabolic processGO:19010692390.064
protein modification by small protein conjugationGO:00324463420.063
negative regulation of cellular protein metabolic processGO:00322693530.061
regulation of kinase activityGO:00435493140.060
behaviorGO:00076101120.059
cellular response to endogenous stimulusGO:00714953360.057
regulation of nucleotide metabolic processGO:00061402690.056
regulation of cell developmentGO:00602841610.055
regulation of wnt signaling pathwayGO:00301111230.055
regulation of cell differentiationGO:00455953930.054
non canonical wnt signaling pathwayGO:0035567140.053
positive regulation of cellular amino acid metabolic processGO:004576430.053
regionalizationGO:0003002290.052
rna 3 end processingGO:0031123350.051
regulation of cellular ketone metabolic processGO:0010565500.051
reproductive processGO:00224141060.050
Mouse
posttranscriptional regulation of gene expressionGO:00106082130.050
enzyme linked receptor protein signaling pathwayGO:00071673030.048
purine ribonucleoside metabolic processGO:00461284370.048
positive regulation of cellular catabolic processGO:00313312840.048
pattern specification processGO:0007389430.046
rho protein signal transductionGO:0007266260.046
viral life cycleGO:00190581320.045
chromatin organizationGO:00063253510.045
positive regulation of cell deathGO:00109422630.045
regulation of transferase activityGO:00513383550.044
purine ribonucleoside triphosphate catabolic processGO:00092073910.043
negative regulation of phosphorylationGO:00423261740.043
regulation of cellular component biogenesisGO:00440872810.043
anatomical structure homeostasisGO:00602491000.042
regulation of purine nucleotide metabolic processGO:19005422640.042
regulation of lipid transportGO:0032368440.041
organophosphate catabolic processGO:00464344300.041
guanosine containing compound metabolic processGO:19010682440.038
response to hormoneGO:00097251750.038
small gtpase mediated signal transductionGO:0007264780.038
regulation of nucleoside metabolic processGO:00091182090.037
histone h4 k8 acetylationGO:0043982150.037
phosphorylation of rna polymerase ii c terminal domainGO:007081630.037
ras protein signal transductionGO:0007265730.037
ribonucleoside catabolic processGO:00424544060.037
positive regulation of wnt signaling pathwayGO:0030177540.036
ribonucleoside triphosphate catabolic processGO:00092033910.036
cellular response to dna damage stimulusGO:00069743790.036
stress activated protein kinase signaling cascadeGO:0031098940.036
activation of protein kinase activityGO:0032147900.036
purine ribonucleoside triphosphate metabolic processGO:00092054110.035
positive regulation of hydrolase activityGO:00513453310.035
positive regulation of transporter activityGO:0032411320.035
nucleoside triphosphate metabolic processGO:00091414220.035
regulation of protein complex assemblyGO:00432541470.034
histone h3 acetylationGO:0043966450.034
regulation of response to drugGO:200102330.034
positive regulation of purine nucleotide metabolic processGO:19005442270.034
positive regulation of gtp catabolic processGO:00331261660.034
regulation of protein serine threonine kinase activityGO:00719001790.033
osteoblast differentiationGO:0001649920.033
cell projection organizationGO:00300302520.033
regulation of dna metabolic processGO:00510521530.033
regulation of anatomical structure sizeGO:00900661010.032
agingGO:0007568660.032
regulation of neurotransmitter secretionGO:004692830.032
negative regulation of protein modification processGO:00314002000.031
regulation of establishment of planar polarityGO:009017550.031
positive regulation of cellular component organizationGO:00511303760.031
single organism reproductive processGO:0044702980.031
Mouse
cellular response to nitrogen compoundGO:19016991440.031
telomere maintenanceGO:0000723320.031
somatic stem cell maintenanceGO:003501940.031
microtubule based processGO:00070172100.030
regulation of nucleotide catabolic processGO:00308112050.030
cellular protein catabolic processGO:00442572610.030
regulation of intracellular transportGO:00323861950.030
negative regulation of dna replicationGO:0008156290.030
lipid metabolic processGO:00066293810.029
cytokine productionGO:00018162470.029
purine nucleoside triphosphate metabolic processGO:00091444120.029
dna repairGO:00062811980.029
nucleoside triphosphate catabolic processGO:00091433940.029
tube morphogenesisGO:0035239950.029
dna modificationGO:0006304270.029
positive regulation of cell differentiationGO:00455972110.029
regulation of cell cycle processGO:00105642660.029
rna processingGO:00063962550.028
regulation of canonical wnt signaling pathwayGO:0060828880.028
positive regulation of nucleotide catabolic processGO:00308131850.028
cellular macromolecular complex assemblyGO:00346223240.028
female gamete generationGO:000729220.028
positive regulation of mrna processingGO:0050685170.028
positive regulation of phosphorylationGO:00423273940.028
multicellular organismal reproductive processGO:0048609400.028
Mouse
regulation of sequence specific dna binding transcription factor activityGO:00510902110.027
histone h4 k16 acetylationGO:0043984140.027
gtp metabolic processGO:00460392390.027
regulation of cellular amino acid metabolic processGO:000652160.027
neuromuscular junction developmentGO:000752830.027
purine nucleoside catabolic processGO:00061523980.027
response to decreased oxygen levelsGO:0036293960.026
positive regulation of cell proliferationGO:00082843010.026
secretion by cellGO:00329402260.026
nucleotide catabolic processGO:00091664080.025
positive regulation of nucleoside metabolic processGO:00459791860.025
neuroblast proliferationGO:000740540.025
ribonucleoside triphosphate metabolic processGO:00091994120.024
positive regulation of protein phosphorylationGO:00019343130.024
epithelium developmentGO:00604292270.024
peripheral nervous system developmentGO:000742220.024
anatomical structure formation involved in morphogenesisGO:00486462840.024
wnt signaling pathway planar cell polarity pathwayGO:006007150.024
regulation of protein processingGO:00706131500.024
organ morphogenesisGO:00098871470.024
peptidyl lysine acetylationGO:00183941010.024
compound eye developmentGO:004874910.024
negative regulation of intracellular signal transductionGO:19025321830.023
reproductionGO:0000003630.022
Mouse
3 utr mediated mrna destabilizationGO:006115810.022
positive regulation of protein transportGO:00512221350.022
ameboidal type cell migrationGO:00016671350.022
spermatid differentiationGO:004851540.022
Mouse
biological adhesionGO:00226103310.022
purine nucleoside triphosphate catabolic processGO:00091463920.022
endocytosisGO:00068971590.022
angiogenesisGO:00015251470.022
positive regulation of organelle organizationGO:00106381950.022
positive regulation of gtpase activityGO:00435471660.022
negative regulation of cell proliferationGO:00082852280.022
lipid localizationGO:00108761060.021
internal peptidyl lysine acetylationGO:0018393970.021
single organism carbohydrate metabolic processGO:00447231930.021
regulation of cell sizeGO:0008361190.021
g1 s transition of mitotic cell cycleGO:0000082780.021
regulation of protein localizationGO:00328802960.021
cardiovascular system developmentGO:00723582620.021
regulation of protein catabolic processGO:00421761550.020
microtubule cytoskeleton organizationGO:00002261760.020
cerebellum developmentGO:002154920.020
regulation of cysteine type endopeptidase activityGO:20001161270.020
regulation of gtp catabolic processGO:00331241800.020
mrna processingGO:00063971330.020
defense responseGO:00069523150.020
cell adhesionGO:00071553250.020
response to organic cyclic compoundGO:00140702040.020
regulation of cell cycleGO:00517263930.019
positive regulation of mrna 3 end processingGO:0031442120.019
negative regulation of cell deathGO:00605483450.019
response to oxygen containing compoundGO:19017003690.019
viral processGO:00160321460.019
response to ionizing radiationGO:0010212650.019
nuclear divisionGO:00002801280.019
regulation of jnk cascadeGO:0046328730.019
response to growth factorGO:00708482050.019
hindbrain developmentGO:003090230.019
response to organonitrogen compoundGO:00102431560.019
proteolysis involved in cellular protein catabolic processGO:00516032440.019
vesicle mediated transportGO:00161923710.019
modification dependent protein catabolic processGO:00199412090.019
positive regulation of nucleotide metabolic processGO:00459812300.018
regulation of mrna processingGO:0050684480.018
regulation of establishment of protein localizationGO:00702012420.018
negative regulation of cellular amino acid metabolic processGO:004576320.018
mrna metabolic processGO:00160711750.018
negative regulation of protein phosphorylationGO:00019331400.018
regulation of secretion by cellGO:19035301770.018
nuclear transcribed mrna catabolic processGO:0000956480.018
actin mediated cell contractionGO:0070252120.018
limbic system developmentGO:002176130.018
negative regulation of synaptic transmissionGO:005080520.018
negative regulation of multicellular organismal processGO:00512413170.018
locomotory behaviorGO:000762610.017
positive regulation of programmed cell deathGO:00430682490.017
positive regulation of purine nucleotide catabolic processGO:00331231850.017
nervous system developmentGO:00073992930.017
digestive tract morphogenesisGO:0048546560.017
regulation of cell morphogenesisGO:00226041530.017
organelle localizationGO:0051640840.017
regulation of purine nucleotide catabolic processGO:00331212050.017
gastrulationGO:0007369510.017
positive regulation of protein kinase activityGO:00458601900.017
immune system developmentGO:00025201950.017
positive regulation of mrna metabolic processGO:1903313190.017
regulation of vesicle mediated transportGO:00606271300.017
regulation of dna repairGO:0006282470.017
cognitionGO:0050890430.017
hemopoiesisGO:00300971800.017
positive regulation of ras gtpase activityGO:00323201170.016
protein stabilizationGO:0050821640.016
regulation of protein transportGO:00512232130.016
dna integrity checkpointGO:0031570710.016
photoreceptor cell differentiationGO:004653020.016
protein ubiquitinationGO:00165673140.016
tissue morphogenesisGO:0048729960.016
cellular chemical homeostasisGO:00550821800.016
negative regulation of endopeptidase activityGO:0010951840.016
response to woundingGO:00096111680.016
peptidyl tyrosine phosphorylationGO:00181081700.016
tube developmentGO:00352951250.016
cellular response to growth factor stimulusGO:00713631970.016
single organism cellular localizationGO:19025803320.016
protein autophosphorylationGO:00467771230.016
regulation of leukocyte activationGO:00026941150.016
cellular response to cytokine stimulusGO:00713451810.016
nucleocytoplasmic transportGO:00069131760.016
negative regulation of transferase activityGO:00513481240.015
reactive oxygen species metabolic processGO:0072593750.015
response to nitrogen compoundGO:19016981840.015
regulation of rho protein signal transductionGO:0035023790.015
oocyte differentiationGO:000999420.015
synaptic vesicle exocytosisGO:001607930.015
unidimensional cell growthGO:000982610.015
regulation of stress activated mapk cascadeGO:0032872840.015
exocytosisGO:0006887710.015
symbiosis encompassing mutualism through parasitismGO:00444031560.015
response to radiationGO:00093141510.015
protein localization to organelleGO:00333652800.015
snrna transcription from rna polymerase iii promoterGO:004279650.015
peptidyl serine modificationGO:00182091060.015
protein processingGO:00164852260.015
positive regulation of cellular component biogenesisGO:00440891580.015
dna replicationGO:00062601160.015
response to axon injuryGO:004867810.015
rna interferenceGO:001624640.014
eye photoreceptor cell differentiationGO:000175420.014
regulation of intracellular protein transportGO:00331571230.014
regulation of gene expression epigeneticGO:0040029730.014
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.014
adult locomotory behaviorGO:000834410.014
regulation of ras protein signal transductionGO:00465781550.014
positive regulation of apoptotic processGO:00430652460.014
establishment or maintenance of cytoskeleton polarityGO:003095230.014
embryonic hemopoiesisGO:003516240.014
jnk cascadeGO:0007254800.014
cell part morphogenesisGO:00329901370.014
protein targetingGO:00066051870.014
negative regulation of proteolysisGO:00458611320.014
regulation of gtpase activityGO:00430871800.014
sexual reproductionGO:0019953370.014
Mouse
spermatid developmentGO:000728640.014
Mouse
regulation of apoptotic signaling pathwayGO:20012331750.014
cellular protein complex assemblyGO:00436231880.014
negative regulation of cellular amine metabolic processGO:003323930.013
protein catabolic processGO:00301633250.013
positive regulation of cell migrationGO:00303351720.013
single organism membrane organizationGO:00448022680.013
regulation of multi organism processGO:00439001570.013
maintenance of locationGO:00512351120.013
peptidyl serine phosphorylationGO:00181051010.013
regulation of transcription from rna polymerase ii promoter in response to stressGO:0043618170.013
signal transduction by phosphorylationGO:00230142970.013
tripartite regional subdivisionGO:000735120.013
cellular carbohydrate metabolic processGO:0044262840.013
regulation of peptidyl tyrosine phosphorylationGO:00507301080.013
rna destabilizationGO:005077910.013
regulation of rna stabilityGO:0043487230.013
positive regulation of map kinase activityGO:0043406800.013
positive regulation of transferase activityGO:00513472270.013
translationGO:00064121320.013
positive regulation of developmental processGO:00510943140.013
cytoplasmic transportGO:00164823790.013
endomembrane system organizationGO:00102561960.013
patterning of blood vesselsGO:000156920.013
chemotaxisGO:00069351570.013
memoryGO:000761330.013
regulation of mapk cascadeGO:00434082620.013
regulation of ossificationGO:0030278580.012
organelle fissionGO:00482851490.012
cellular response to drugGO:0035690270.012
intracellular protein transportGO:00068862700.012
negative regulation of programmed cell deathGO:00430693210.012
protein acetylationGO:00064731160.012
regulation of actin filament based processGO:00329701410.012
regulation of nucleocytoplasmic transportGO:0046822980.012
positive regulation of mapk cascadeGO:00434101900.012
cellular response to hormone stimulusGO:00328701250.012
inner ear morphogenesisGO:004247240.012
visual behaviorGO:000763220.012
cellular response to oxygen levelsGO:0071453550.012
cation transmembrane transportGO:00986552380.012
regulation of cytoplasmic transportGO:19036491490.012
morphogenesis of an epitheliumGO:0002009600.012
regulation of angiogenesisGO:0045765920.012
leukocyte proliferationGO:0070661740.012
regulation of axon extension involved in axon guidanceGO:004884120.012
epithelial cell differentiationGO:00308551410.012
negative regulation of protein processingGO:00109551420.012
regulation of cellular component movementGO:00512703340.012
mitotic cell cycle processGO:19030472860.011
regulation of dna replicationGO:0006275680.011
positive regulation of multi organism processGO:0043902560.011
regulation of small gtpase mediated signal transductionGO:00510561560.011
regulation of response to cytokine stimulusGO:0060759460.011
cell cycle g2 m phase transitionGO:0044839430.011
regenerationGO:003109940.011
extrinsic apoptotic signaling pathwayGO:00971911190.011
cellular response to organonitrogen compoundGO:00714171240.011
apoptotic signaling pathwayGO:00971902680.011
positive regulation of intracellular transportGO:00323881040.011
organophosphate biosynthetic processGO:00904071630.011
regulation of chromosome organizationGO:00330441030.011
brain developmentGO:0007420970.011
histone h3 k4 trimethylationGO:008018270.011
ossificationGO:00015031210.011
motor neuron axon guidanceGO:000804520.011
response to lipidGO:00339932060.011
membrane organizationGO:00610242920.011
regulation of cell activationGO:00508651250.011
sensory perceptionGO:00076001030.011
response to bacteriumGO:00096171440.011
negative regulation of kinase activityGO:00336731060.011
protein localization to membraneGO:00726571600.011
negative regulation of cysteine type endopeptidase activityGO:2000117480.011
organic hydroxy compound metabolic processGO:19016151470.011
inorganic ion transmembrane transportGO:00986602310.011
regulation of growthGO:00400081650.011
regulation of synaptic plasticityGO:004816730.011
protein maturationGO:00516042330.011
regulation of lymphocyte activationGO:00512491030.011
negative regulation of cell differentiationGO:00455961710.011
nucleic acid phosphodiester bond hydrolysisGO:00903051020.011
blood vessel morphogenesisGO:00485141620.011
regulation of cell motilityGO:20001452990.011
organonitrogen compound biosynthetic processGO:19015662000.011
g2 m transition of mitotic cell cycleGO:0000086410.011
multicellular organism reproductionGO:0032504420.011
Mouse
growthGO:00400072020.011
carbohydrate metabolic processGO:00059752070.011
visual learningGO:000854210.011
positive regulation of cellular component movementGO:00512721810.011
actin filament based movementGO:0030048170.011
reactive oxygen species biosynthetic processGO:190340940.011
ubiquitin dependent protein catabolic processGO:00065112060.010
endosomal transportGO:00161971290.010
negative regulation of catabolic processGO:00098951040.010
positive regulation of axon extensionGO:004577340.010
cellular homeostasisGO:00197251960.010
regulation of immune responseGO:00507762010.010
regulation of actin cytoskeleton organizationGO:00329561160.010
regulation of transforming growth factor beta receptor signaling pathwayGO:0017015480.010
regulation of ras gtpase activityGO:00323181280.010
negative regulation of protein kinase activityGO:0006469980.010
release of cytoplasmic sequestered nf kappabGO:000858840.010
associative learningGO:000830610.010
protein targeting to membraneGO:0006612420.010
purine ribonucleoside catabolic processGO:00461303980.010
negative regulation of apoptotic processGO:00430663160.010
interspecies interaction between organismsGO:00444191560.010
negative regulation of transportGO:00510511760.010
regulation of vasculature developmentGO:1901342970.010
meiosis iGO:000712740.010

AFF4 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:145661740.058
cancerDOID:1621670.029
organ system cancerDOID:00506861640.014
disease of metabolismDOID:00146672950.013