Homo sapiens

15 known processes

MLH3

mutL homolog 3 (E. coli)

(Aliases: HNPCC7,MGC138372)

MLH3 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
post embryonic developmentGO:000979120.063
female gamete generationGO:000729220.049
cellular amino acid metabolic processGO:00065201160.048
meiosis iGO:000712740.045
multicellular organismal agingGO:001025930.045
determination of adult lifespanGO:000834020.043
amine metabolic processGO:0009308440.038
regulation of cellular amine metabolic processGO:0033238110.038
cellular ketone metabolic processGO:0042180800.037
cellular amine metabolic processGO:0044106410.037
regulation of cellular ketone metabolic processGO:0010565500.037
regulation of cellular amino acid metabolic processGO:000652160.035
cellular macromolecular complex assemblyGO:00346223240.034
positive regulation of cellular amino acid metabolic processGO:004576430.032
oogenesisGO:004847720.031
cellular response to dna damage stimulusGO:00069743790.031
positive regulation of cellular amine metabolic processGO:003324070.030
purine nucleotide catabolic processGO:00061954050.030
cytoplasmic transportGO:00164823790.030
glycosyl compound catabolic processGO:19016584130.029
organophosphate catabolic processGO:00464344300.029
ribonucleoside catabolic processGO:00424544060.028
ribonucleotide catabolic processGO:00092614050.028
locomotory behaviorGO:000762610.028
nucleoside triphosphate metabolic processGO:00091414220.028
purine ribonucleoside metabolic processGO:00461284370.028
immune responseGO:00069553070.027
purine ribonucleoside catabolic processGO:00461303980.027
purine nucleoside catabolic processGO:00061523980.027
purine containing compound catabolic processGO:00725234110.027
cellular macromolecule catabolic processGO:00442653800.027
segmentationGO:003528240.027
dna repairGO:00062811980.026
negative regulation of cellular protein metabolic processGO:00322693530.026
negative regulation of protein metabolic processGO:00512483910.026
nucleotide catabolic processGO:00091664080.026
purine ribonucleoside triphosphate catabolic processGO:00092073910.025
ribonucleoside triphosphate catabolic processGO:00092033910.025
ribonucleoside triphosphate metabolic processGO:00091994120.025
nucleoside phosphate catabolic processGO:19012924120.025
single organism cellular localizationGO:19025803320.025
nucleoside triphosphate catabolic processGO:00091433940.025
lipid metabolic processGO:00066293810.025
positive regulation of catabolic processGO:00098963100.024
organelle fissionGO:00482851490.024
cellular component morphogenesisGO:00329893140.024
purine nucleoside triphosphate metabolic processGO:00091444120.024
regulation of cell cycleGO:00517263930.024
positive regulation of phosphorylationGO:00423273940.024
positive regulation of cellular component organizationGO:00511303760.024
apoptotic signaling pathwayGO:00971902680.024
cellular lipid metabolic processGO:00442553030.024
positive regulation of hydrolase activityGO:00513453310.024
mitotic cell cycleGO:00002783260.024
negative regulation of catalytic activityGO:00430863350.024
purine nucleoside triphosphate catabolic processGO:00091463920.023
purine ribonucleoside triphosphate metabolic processGO:00092054110.023
purine ribonucleotide catabolic processGO:00091544040.023
ras protein signal transductionGO:0007265730.022
regulation of cell cycle processGO:00105642660.022
positive regulation of cellular catabolic processGO:00313312840.022
cell morphogenesisGO:00009022960.022
regulation of protein localizationGO:00328802960.022
nucleoside catabolic processGO:00091644080.022
transmembrane transportGO:00550853990.022
small gtpase mediated signal transductionGO:0007264780.022
intracellular protein transportGO:00068862700.022
protein localization to organelleGO:00333652800.022
protein catabolic processGO:00301633250.022
neuromuscular junction developmentGO:000752830.022
system processGO:00030083490.021
regulation of cell differentiationGO:00455953930.021
regenerationGO:003109940.021
negative regulation of programmed cell deathGO:00430693210.021
memoryGO:000761330.021
positive regulation of transportGO:00510503360.021
membrane organizationGO:00610242920.021
protein maturationGO:00516042330.021
vesicle mediated transportGO:00161923710.020
mitotic cell cycle processGO:19030472860.020
response to oxygen containing compoundGO:19017003690.020
single organism membrane organizationGO:00448022680.020
regulation of transferase activityGO:00513383550.020
negative regulation of apoptotic processGO:00430663160.020
nuclear divisionGO:00002801280.020
anterior posterior axis specificationGO:000994820.020
cell projection organizationGO:00300302520.020
cellular protein complex assemblyGO:00436231880.020
regulation of proteolysisGO:00301622930.020
organelle assemblyGO:00709251760.020
response to abiotic stimulusGO:00096283360.020
biological adhesionGO:00226103310.019
ion transmembrane transportGO:00342203380.019
actin filament based processGO:00300292240.019
cellular protein catabolic processGO:00442572610.019
cation transportGO:00068123310.019
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.019
negative regulation of phosphorus metabolic processGO:00105632670.019
release of cytoplasmic sequestered nf kappabGO:000858840.019
dephosphorylationGO:00163112090.019
positive regulation of cell deathGO:00109422630.019
negative regulation of cell deathGO:00605483450.019
anatomical structure formation involved in morphogenesisGO:00486462840.019
cell adhesionGO:00071553250.019
regulation of kinase activityGO:00435493140.018
regulation of nucleotide metabolic processGO:00061402690.018
chromatin organizationGO:00063253510.018
organonitrogen compound biosynthetic processGO:19015662000.018
blastoderm segmentationGO:000735020.018
negative regulation of phosphate metabolic processGO:00459362670.018
carbohydrate derivative biosynthetic processGO:19011372070.018
oocyte developmentGO:004859910.018
nervous system developmentGO:00073992930.018
chemical homeostasisGO:00488783060.018
meiotic chromosome segregationGO:004513240.018
nitrogen compound transportGO:00717051910.018
rna processingGO:00063962550.017
negative regulation of cellular amino acid metabolic processGO:004576320.017
positive regulation of purine nucleotide metabolic processGO:19005442270.017
adult locomotory behaviorGO:000834410.017
cellular response to endogenous stimulusGO:00714953360.017
metal ion transportGO:00300012720.017
positive regulation of programmed cell deathGO:00430682490.017
regulation of establishment of protein localizationGO:00702012420.017
positive regulation of protein phosphorylationGO:00019343130.017
negative regulation of cellular amine metabolic processGO:003323930.017
regulation of purine nucleotide metabolic processGO:19005422640.017
proteolysis involved in cellular protein catabolic processGO:00516032440.017
microtubule based processGO:00070172100.017
histone modificationGO:00165702510.017
regulation of cytokine productionGO:00018172320.017
regulation of anatomical structure morphogenesisGO:00226032860.017
protein processingGO:00164852260.017
positive regulation of developmental processGO:00510943140.017
regulation of cellular component movementGO:00512703340.017
mapk cascadeGO:00001652880.017
cell developmentGO:00484683280.017
oxidation reduction processGO:00551143960.017
negative regulation of intracellular signal transductionGO:19025321830.017
innate immune responseGO:00450871780.017
signal transduction by phosphorylationGO:00230142970.017
positive regulation of apoptotic processGO:00430652460.017
reactive nitrogen species metabolic processGO:200105730.017
defense responseGO:00069523150.017
gtp metabolic processGO:00460392390.017
morphogenesis of embryonic epitheliumGO:001633140.017
spermatid differentiationGO:004851540.016
chromatin modificationGO:00165682980.016
response to cytokineGO:00340972320.016
regulation of protein transportGO:00512232130.016
regulation of meiotic cell cycleGO:005144540.016
hindbrain developmentGO:003090230.016
ion homeostasisGO:00508012300.016
positive regulation of immune system processGO:00026842830.016
negative regulation of cell cycleGO:00457861930.016
maintenance of locationGO:00512351120.016
reactive oxygen species biosynthetic processGO:190340940.016
guanosine containing compound catabolic processGO:19010692390.016
protein targetingGO:00066051870.016
posttranscriptional regulation of gene expressionGO:00106082130.016
regulation of protein kinase activityGO:00458592890.016
oocyte differentiationGO:000999420.016
carbohydrate metabolic processGO:00059752070.016
regulation of nucleoside metabolic processGO:00091182090.016
peripheral nervous system developmentGO:000742220.016
cellular response to oxygen containing compoundGO:19017012760.016
positive regulation of nucleotide metabolic processGO:00459812300.016
neurotransmitter secretionGO:000726940.016
cation transmembrane transportGO:00986552380.016
protein ubiquitinationGO:00165673140.015
guanosine containing compound metabolic processGO:19010682440.015
negative regulation of cellular component organizationGO:00511292350.015
cytokine productionGO:00018162470.015
gtp catabolic processGO:00061842370.015
rhythmic behaviorGO:000762220.015
dna recombinationGO:0006310770.015
mitochondrion organizationGO:00070051560.015
regulation of purine nucleotide catabolic processGO:00331212050.015
negative regulation of cell proliferationGO:00082852280.015
regulation of locomotionGO:00400123290.015
covalent chromatin modificationGO:00165692540.015
ubiquitin dependent protein catabolic processGO:00065112060.015
positive regulation of nucleoside metabolic processGO:00459791860.015
lipid biosynthetic processGO:00086101770.015
rho protein signal transductionGO:0007266260.015
negative regulation of hydrolase activityGO:00513461820.015
regulation of dna metabolic processGO:00510521530.015
protein modification by small protein conjugationGO:00324463420.015
microtubule cytoskeleton organizationGO:00002261760.015
regulation of intracellular transportGO:00323861950.015
regulation of cellular component biogenesisGO:00440872810.015
spermatid developmentGO:000728640.015
response to external biotic stimulusGO:00432072610.015
negative regulation of multicellular organismal processGO:00512413170.015
regulation of synaptic plasticityGO:004816730.015
regulation of cell motilityGO:20001452990.015
single organism carbohydrate metabolic processGO:00447231930.015
proteasomal protein catabolic processGO:00104981760.015
regulation of nucleotide catabolic processGO:00308112050.015
monocarboxylic acid metabolic processGO:00327871850.015
establishment of protein localization to organelleGO:00725941720.015
cell divisionGO:00513011680.015
regulation of mapk cascadeGO:00434082620.015
reciprocal meiotic recombinationGO:000713140.015
regulation of secretionGO:00510461940.015
small molecule biosynthetic processGO:00442831570.014
regulation of response to external stimulusGO:00321012220.014
positive regulation of organelle organizationGO:00106381950.014
positive regulation of purine nucleotide catabolic processGO:00331231850.014
positive regulation of cell proliferationGO:00082843010.014
associative learningGO:000830610.014
secretionGO:00469032540.014
response to biotic stimulusGO:00096072760.014
regulation of reactive oxygen species biosynthetic processGO:190342630.014
inorganic ion transmembrane transportGO:00986602310.014
tripartite regional subdivisionGO:000735120.014
regulation of cellular response to stressGO:00801352440.014
cardiac muscle cell contractionGO:008600340.014
response to organic cyclic compoundGO:00140702040.014
purine nucleoside monophosphate metabolic processGO:00091261860.014
nuclear transportGO:00511691790.014
inner ear morphogenesisGO:004247240.014
secretion by cellGO:00329402260.014
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.014
inorganic cation transmembrane transportGO:00986621940.014
compound eye developmentGO:004874910.014
reactive oxygen species metabolic processGO:0072593750.014
positive regulation of transcription from rna polymerase ii promoter during mitosisGO:004602210.014
response to axon injuryGO:004867810.014
anterior posterior axis specification embryoGO:000859520.014
photoreceptor cell differentiationGO:004653020.014
positive regulation of transferase activityGO:00513472270.014
motor neuron axon guidanceGO:000804520.014
epithelium developmentGO:00604292270.014
immune system developmentGO:00025201950.014
cellular response to cytokine stimulusGO:00713451810.014
regulation of sequence specific dna binding transcription factor activityGO:00510902110.014
cell activationGO:00017752130.014
positive regulation of kinase activityGO:00336742040.014
regulation of mitotic cell cycleGO:00073461890.014
chromosome segregationGO:00070591140.014
regulation of transcription from rna polymerase ii promoter mitoticGO:004602110.014
negative regulation of cell cycle processGO:00109481210.013
circadian behaviorGO:004851220.013
regulation of protein catabolic processGO:00421761550.013
organ formationGO:004864530.013
regulation of cell migrationGO:00303342890.013
regulation of transcription during mitosisGO:004589620.013
cell projection assemblyGO:00300311260.013
anion transportGO:00068201610.013
cellular homeostasisGO:00197251960.013
morphogenesis of a polarized epitheliumGO:000173830.013
regulation of gtpase activityGO:00430871800.013
male meiosisGO:000714010.013
nerve developmentGO:002167540.013
positive regulation of transcription during mitosisGO:004589720.013
modification dependent protein catabolic processGO:00199412090.013
positive regulation of cell differentiationGO:00455972110.013
metencephalon developmentGO:002203720.013
protein localization to membraneGO:00726571600.013
regulation of immune responseGO:00507762010.013
cell growthGO:00160491600.013
matingGO:000761810.013
negative regulation of protein modification processGO:00314002000.013
regulation of meiosisGO:004002030.013
purine ribonucleoside monophosphate metabolic processGO:00091671860.013
regulation of gtp catabolic processGO:00331241800.013
regulation of protein maturationGO:19033171500.013
positive regulation of reactive oxygen species biosynthetic processGO:190342820.013
positive regulation of gtpase activityGO:00435471660.013
mrna metabolic processGO:00160711750.013
regulation of neural precursor cell proliferationGO:200017740.013
modification dependent macromolecule catabolic processGO:00436322120.013
negative regulation of transportGO:00510511760.013
tissue regenerationGO:004224630.013
ribonucleoside monophosphate metabolic processGO:00091611870.013
negative regulation of developmental processGO:00510932470.013
actin filament based movementGO:0030048170.013
growthGO:00400072020.013
regulation of protein processingGO:00706131500.013
nucleic acid phosphodiester bond hydrolysisGO:00903051020.012
cell cycle phase transitionGO:00447701730.012
rna interferenceGO:001624640.012
enzyme linked receptor protein signaling pathwayGO:00071673030.012
neurological system processGO:00508771630.012
organophosphate biosynthetic processGO:00904071630.012
protein oligomerizationGO:00512591730.012
positive regulation of synaptic transmissionGO:005080640.012
peptidyl lysine modificationGO:00182051440.012
syncytium formation by plasma membrane fusionGO:000076820.012
circulatory system developmentGO:00723592620.012
regulation of endopeptidase activityGO:00525481700.012
long term memoryGO:000761620.012
visual behaviorGO:000763220.012
response to lipidGO:00339932060.012
sequestering of metal ionGO:0051238240.012
response to fungusGO:000962040.012
embryonic epithelial tube formationGO:000183840.012
protein acylationGO:00435431380.012
divalent inorganic cation transportGO:00725111580.012
cellular chemical homeostasisGO:00550821800.012
atp metabolic processGO:00460341760.012
actin cytoskeleton organizationGO:00300362070.012
regulation of multi organism processGO:00439001570.012
positive regulation of nucleotide catabolic processGO:00308131850.012
endomembrane system organizationGO:00102561960.012
endosomal transportGO:00161971290.012
nucleoside monophosphate metabolic processGO:00091231910.012
negative regulation of protein maturationGO:19033181420.012
regulation of peptidase activityGO:00525471800.012
leukocyte activationGO:00453211640.012
salivary gland morphogenesisGO:000743540.012
actin mediated cell contractionGO:0070252120.012
positive regulation of cytokine productionGO:00018191670.012
spinal cord developmentGO:002151040.012
negative regulation of protein processingGO:00109551420.012
neuroblast proliferationGO:000740540.012
immune effector processGO:00022521590.012
mrna processingGO:00063971330.012
cell part morphogenesisGO:00329901370.012
cation homeostasisGO:00550801890.012
regulation of cytoskeleton organizationGO:00514931770.012
negative regulation of phosphorylationGO:00423261740.012
response to woundingGO:00096111680.011
regulation of cytoplasmic transportGO:19036491490.011
mitotic cell cycle phase transitionGO:00447721620.011
response to nitrogen compoundGO:19016981840.011
metal ion homeostasisGO:00550651690.011
establishment of protein localization to membraneGO:00901501210.011
glycoprotein metabolic processGO:00091001100.011
double strand break repairGO:00063021010.011
limbic system developmentGO:002176130.011
regulation of secretion by cellGO:19035301770.011
neural tube formationGO:000184130.011
sensory perception of painGO:001923340.011
thymus developmentGO:004853830.011
response to growth factorGO:00708482050.011
regulation of growthGO:00400081650.011
regulation of apoptotic signaling pathwayGO:20012331750.011
response to other organismGO:00517072610.011
regulation of vesicle mediated transportGO:00606271300.011
nucleoside monophosphate catabolic processGO:00091251590.011
stem cell divisionGO:001714520.011
regulation of small gtpase mediated signal transductionGO:00510561560.011
protein localization to nucleusGO:00345041360.011
regulation of reactive oxygen species metabolic processGO:2000377410.011
organic anion transportGO:00157111030.011
cell fate determinationGO:000170930.011
somitogenesisGO:000175620.011
regulation of cell morphogenesisGO:00226041530.011
response to hormoneGO:00097251750.011
positive regulation of gtp catabolic processGO:00331261660.011
negative regulation of proteolysisGO:00458611320.011
nucleocytoplasmic transportGO:00069131760.011
myoblast fusionGO:000752010.011
cellular ion homeostasisGO:00068731680.011
regulation of ras protein signal transductionGO:00465781550.011
reciprocal dna recombinationGO:003582540.011
regulation of i kappab kinase nf kappab signalingGO:00431221620.011
positive regulation of protein kinase activityGO:00458601900.011
cell projection morphogenesisGO:00488581290.011
sequestering of calcium ionGO:0051208170.011
calcium ion transportGO:00068161470.011
establishment of planar polarityGO:000173630.011
i kappab kinase nf kappab signalingGO:00072491660.011
sex determinationGO:000753030.011
divalent metal ion transportGO:00708381520.011
cardiovascular system developmentGO:00723582620.011
positive regulation of cellular component movementGO:00512721810.011
cellular cation homeostasisGO:00300031630.011
regulation of cell growthGO:00015581350.011
ribonucleoside monophosphate catabolic processGO:00091581580.011
positive regulation of locomotionGO:00400171860.011
negative regulation of transferase activityGO:00513481240.011
positive regulation of cell motilityGO:20001471770.011
cilium organizationGO:0044782680.011
positive regulation of immune responseGO:00507781590.011
endocytosisGO:00068971590.011
organic hydroxy compound metabolic processGO:19016151470.011
regulation of protein complex assemblyGO:00432541470.011
cranial nerve developmentGO:002154540.011
regulation of cell cycle phase transitionGO:19019871260.011
cerebellum developmentGO:002154920.011
positive regulation of reactive oxygen species metabolic processGO:2000379240.011
developmental programmed cell deathGO:001062330.011
cellular response to growth factor stimulusGO:00713631970.011
organic acid biosynthetic processGO:0016053970.011
interspecies interaction between organismsGO:00444191560.011
neural tube closureGO:000184330.010
positive regulation of cell migrationGO:00303351720.010
cellular metal ion homeostasisGO:00068751460.010
regulation of protein serine threonine kinase activityGO:00719001790.010
establishment of tissue polarityGO:000716430.010
regulation of ion transportGO:00432691890.010
regulation of cell divisionGO:00513021160.010
carboxylic acid biosynthetic processGO:0046394970.010
translationGO:00064121320.010
neurogenesisGO:00220081690.010
cilium morphogenesisGO:0060271750.010
response to organonitrogen compoundGO:00102431560.010
wnt signaling pathwayGO:00160551560.010
positive regulation of protein transportGO:00512221350.010
single organism cell adhesionGO:00986021790.010
multi organism cellular processGO:00447641560.010
purine ribonucleoside monophosphate catabolic processGO:00091691580.010
regulation of glial cell differentiationGO:004568530.010
tube closureGO:006060630.010
epidermis morphogenesisGO:004873030.010
positive regulation of ras gtpase activityGO:00323201170.010
t cell differentiation in thymusGO:003307740.010
symbiosis encompassing mutualism through parasitismGO:00444031560.010
protein dephosphorylationGO:0006470810.010
negative regulation of organelle organizationGO:00106391260.010
phospholipid metabolic processGO:0006644990.010
cofactor metabolic processGO:0051186870.010
negative regulation of protein phosphorylationGO:00019331400.010
lung alveolus developmentGO:004828640.010
positive regulation of cellular component biogenesisGO:00440891580.010
response to virusGO:00096151260.010
glycerolipid metabolic processGO:00464861070.010
forelimb morphogenesisGO:003513640.010

MLH3 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:00146672950.038
musculoskeletal system diseaseDOID:172230.029
inherited metabolic disorderDOID:6552420.026
disease of cellular proliferationDOID:145661740.024
cancerDOID:1621670.024
nervous system diseaseDOID:8634310.024
sensory system diseaseDOID:00501552030.024
immune system diseaseDOID:29141550.023
organ system cancerDOID:00506861640.021
central nervous system diseaseDOID:3311860.020
eye and adnexa diseaseDOID:14921500.020
eye diseaseDOID:56141490.020
cardiovascular system diseaseDOID:12871060.016
muscular diseaseDOID:00800001140.016
retinal diseaseDOID:56791180.016
muscle tissue diseaseDOID:661130.016
connective tissue diseaseDOID:651090.016
myopathyDOID:4231040.015
neurodegenerative diseaseDOID:12891020.015
bone diseaseDOID:0080001880.014
hematopoietic system diseaseDOID:741000.013
amino acid metabolic disorderDOID:9252500.013
brain diseaseDOID:936730.011
retinal degenerationDOID:8466890.011
heart diseaseDOID:114680.011
disease of mental healthDOID:150700.010
gastrointestinal system cancerDOID:3119520.008
colorectal cancerDOID:9256290.004
large intestine cancerDOID:5672290.004
intestinal cancerDOID:10155290.004
colon cancerDOID:219250.004
colon carcinomaDOID:1520250.004
reproductive organ cancerDOID:193230.004
female reproductive organ cancerDOID:120100.002
uterine cancerDOID:36340.000
endometrial carcinomaDOID:287140.000
endometrial cancerDOID:138040.000