Homo sapiens

0 known processes

APLN

apelin

(Aliases: APEL,XNPEP2)

APLN biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.126
segmentationGO:003528240.095
amine metabolic processGO:0009308440.064
extraocular skeletal muscle developmentGO:000207410.061
post embryonic developmentGO:000979120.060
cellular amine metabolic processGO:0044106410.056
cellular amino acid metabolic processGO:00065201160.050
regulation of kinase activityGO:00435493140.050
organ formationGO:004864530.049
cellular ketone metabolic processGO:0042180800.049
transmembrane transportGO:00550853990.049
negative regulation of cell deathGO:00605483450.048
regulation of anatomical structure morphogenesisGO:00226032860.047
regulation of cellular ketone metabolic processGO:0010565500.047
regulation of cellular amino acid metabolic processGO:000652160.044
system processGO:00030083490.042
positive regulation of transportGO:00510503360.040
cyclic nucleotide metabolic processGO:0009187820.040
lipid metabolic processGO:00066293810.040
positive regulation of developmental processGO:00510943140.039
regulation of transferase activityGO:00513383550.038
negative regulation of programmed cell deathGO:00430693210.038
mapk cascadeGO:00001652880.037
ras protein signal transductionGO:0007265730.037
positive regulation of cellular amine metabolic processGO:003324070.037
anatomical structure formation involved in morphogenesisGO:00486462840.037
regulation of cellular amine metabolic processGO:0033238110.037
neuromuscular junction developmentGO:000752830.037
regulation of cell differentiationGO:00455953930.037
regulation of cellular component biogenesisGO:00440872810.036
actin filament based processGO:00300292240.036
locomotory behaviorGO:000762610.036
negative regulation of cellular protein metabolic processGO:00322693530.036
regulation of proteolysisGO:00301622930.036
carbohydrate derivative biosynthetic processGO:19011372070.035
multicellular organismal agingGO:001025930.035
nervous system developmentGO:00073992930.035
vesicle mediated transportGO:00161923710.035
positive regulation of cell proliferationGO:00082843010.035
positive regulation of cellular amino acid metabolic processGO:004576430.035
regulation of purine nucleotide metabolic processGO:19005422640.034
positive regulation of cellular component organizationGO:00511303760.034
negative regulation of catalytic activityGO:00430863350.034
ion transmembrane transportGO:00342203380.034
negative regulation of protein metabolic processGO:00512483910.033
female gamete generationGO:000729220.033
cellular response to endogenous stimulusGO:00714953360.033
determination of adult lifespanGO:000834020.033
anion transportGO:00068201610.033
small gtpase mediated signal transductionGO:0007264780.032
protein maturationGO:00516042330.032
regulation of sequence specific dna binding transcription factor activityGO:00510902110.032
epithelium developmentGO:00604292270.032
negative regulation of phosphate metabolic processGO:00459362670.032
positive regulation of transferase activityGO:00513472270.031
photoreceptor cell differentiationGO:004653020.031
cation transmembrane transportGO:00986552380.031
regulation of nucleotide metabolic processGO:00061402690.031
negative regulation of apoptotic processGO:00430663160.031
response to cytokineGO:00340972320.031
reactive oxygen species metabolic processGO:0072593750.030
response to oxygen containing compoundGO:19017003690.030
blastoderm segmentationGO:000735020.030
positive regulation of hydrolase activityGO:00513453310.030
organophosphate catabolic processGO:00464344300.030
cell adhesionGO:00071553250.030
regulation of protein localizationGO:00328802960.029
positive regulation of phosphorylationGO:00423273940.029
cytoplasmic transportGO:00164823790.029
regulation of endopeptidase activityGO:00525481700.029
biological adhesionGO:00226103310.029
cellular lipid metabolic processGO:00442553030.029
organonitrogen compound biosynthetic processGO:19015662000.029
oogenesisGO:004847720.029
ribonucleoside triphosphate catabolic processGO:00092033910.029
hindbrain developmentGO:003090230.028
mitotic cell cycleGO:00002783260.028
memoryGO:000761330.028
neuron fate commitmentGO:004866320.028
negative regulation of multicellular organismal processGO:00512413170.028
single organism cellular localizationGO:19025803320.028
nucleoside triphosphate metabolic processGO:00091414220.028
nucleoside catabolic processGO:00091644080.028
regulation of protein kinase activityGO:00458592890.028
cellular response to dna damage stimulusGO:00069743790.028
chemical homeostasisGO:00488783060.028
purine ribonucleoside metabolic processGO:00461284370.028
nucleoside phosphate catabolic processGO:19012924120.028
nucleoside triphosphate catabolic processGO:00091433940.028
ribonucleotide catabolic processGO:00092614050.027
purine nucleoside triphosphate catabolic processGO:00091463920.027
organophosphate biosynthetic processGO:00904071630.027
purine containing compound catabolic processGO:00725234110.027
cellular macromolecular complex assemblyGO:00346223240.027
response to organic cyclic compoundGO:00140702040.027
ribonucleoside triphosphate metabolic processGO:00091994120.026
metencephalon developmentGO:002203720.026
positive regulation of protein phosphorylationGO:00019343130.026
carbohydrate metabolic processGO:00059752070.026
protein processingGO:00164852260.026
regulation of cellular response to stressGO:00801352440.026
metal ion transportGO:00300012720.026
regulation of cysteine type endopeptidase activityGO:20001161270.025
specification of organ identityGO:001009230.025
inner ear morphogenesisGO:004247240.025
ribonucleoside catabolic processGO:00424544060.025
negative regulation of phosphorus metabolic processGO:00105632670.025
positive regulation of protein kinase activityGO:00458601900.025
hematopoietic or lymphoid organ developmentGO:00485341860.025
signal transduction by phosphorylationGO:00230142970.025
cranial nerve developmentGO:002154540.025
regulation of branching involved in ureteric bud morphogenesisGO:009018930.025
nucleoside phosphate biosynthetic processGO:19012931090.024
cation transportGO:00068123310.024
mitotic cell cycle processGO:19030472860.024
associative learningGO:000830610.024
cell morphogenesisGO:00009022960.024
purine ribonucleoside triphosphate catabolic processGO:00092073910.024
peripheral nervous system developmentGO:000742220.024
rho protein signal transductionGO:0007266260.024
positive regulation of programmed cell deathGO:00430682490.024
embryonic epithelial tube formationGO:000183840.024
positive regulation of apoptotic processGO:00430652460.024
negative regulation of developmental processGO:00510932470.024
response to abiotic stimulusGO:00096283360.024
cell developmentGO:00484683280.024
positive regulation of cellular catabolic processGO:00313312840.024
taxisGO:00423301570.023
ion homeostasisGO:00508012300.023
regulation of cell developmentGO:00602841610.023
glycosyl compound catabolic processGO:19016584130.023
anterior posterior axis specificationGO:000994820.023
cardiovascular system developmentGO:00723582620.023
lipid biosynthetic processGO:00086101770.023
regulation of peptidase activityGO:00525471800.023
positive regulation of catabolic processGO:00098963100.023
morphogenesis of embryonic epitheliumGO:001633140.023
immune responseGO:00069553070.022
inorganic cation transmembrane transportGO:00986621940.022
cell morphogenesis involved in differentiationGO:00009041440.022
purine ribonucleoside triphosphate metabolic processGO:00092054110.022
negative regulation of cell proliferationGO:00082852280.022
secretion by cellGO:00329402260.022
central nervous system developmentGO:00074171230.022
blood vessel morphogenesisGO:00485141620.022
positive regulation of kinase activityGO:00336742040.022
purine nucleoside catabolic processGO:00061523980.022
single organism membrane organizationGO:00448022680.022
positive regulation of cell deathGO:00109422630.022
negative regulation of cellular component organizationGO:00511292350.022
apoptotic signaling pathwayGO:00971902680.022
nucleotide biosynthetic processGO:00091651090.022
cellular component morphogenesisGO:00329893140.021
negative regulation of hydrolase activityGO:00513461820.021
nucleotide catabolic processGO:00091664080.021
positive regulation of purine nucleotide metabolic processGO:19005442270.021
regulation of protein serine threonine kinase activityGO:00719001790.021
neurological system processGO:00508771630.021
regulation of cell migrationGO:00303342890.021
protein catabolic processGO:00301633250.020
cellular response to oxygen containing compoundGO:19017012760.020
response to lipidGO:00339932060.020
cellular macromolecule catabolic processGO:00442653800.020
regulation of cellular component movementGO:00512703340.020
organ morphogenesisGO:00098871470.020
peptidyl tyrosine phosphorylationGO:00181081700.020
positive regulation of organelle organizationGO:00106381950.020
growthGO:00400072020.020
secretionGO:00469032540.020
protein localization to organelleGO:00333652800.020
cation homeostasisGO:00550801890.020
purine ribonucleoside catabolic processGO:00461303980.020
cellular ion homeostasisGO:00068731680.020
actin cytoskeleton organizationGO:00300362070.020
generation of neuronsGO:00486991520.020
positive regulation of nucleotide metabolic processGO:00459812300.020
dephosphorylationGO:00163112090.020
defense responseGO:00069523150.019
enzyme linked receptor protein signaling pathwayGO:00071673030.019
negative regulation of cellular amino acid metabolic processGO:004576320.019
immune system developmentGO:00025201950.019
purine nucleoside triphosphate metabolic processGO:00091444120.019
spermatid differentiationGO:004851540.019
response to hormoneGO:00097251750.019
head developmentGO:00603221080.019
regulation of vesicle mediated transportGO:00606271300.019
regulation of cell cycleGO:00517263930.019
intracellular protein transportGO:00068862700.019
regulation of cell motilityGO:20001452990.019
circulatory system developmentGO:00723592620.019
regulation of response to external stimulusGO:00321012220.019
calcium ion transportGO:00068161470.019
regenerationGO:003109940.019
regulation of protein maturationGO:19033171500.019
oxidation reduction processGO:00551143960.019
regulation of reactive oxygen species metabolic processGO:2000377410.019
heart formationGO:006091420.019
single organism cell adhesionGO:00986021790.019
vasculature developmentGO:00019441810.019
cellular protein catabolic processGO:00442572610.019
regulation of neural precursor cell proliferationGO:200017740.019
purine ribonucleotide catabolic processGO:00091544040.019
regulation of cytoskeleton organizationGO:00514931770.019
regulation of growthGO:00400081650.018
purine nucleotide catabolic processGO:00061954050.018
negative regulation of intracellular signal transductionGO:19025321830.018
cellular response to cytokine stimulusGO:00713451810.018
positive regulation of secretionGO:00510471160.018
reactive oxygen species biosynthetic processGO:190340940.018
cardiac muscle cell contractionGO:008600340.018
axis elongationGO:000340140.018
nitrogen compound transportGO:00717051910.018
membrane organizationGO:00610242920.018
glial cell migrationGO:000834740.018
cell projection organizationGO:00300302520.018
cellular chemical homeostasisGO:00550821800.018
purine nucleotide biosynthetic processGO:0006164840.018
canonical wnt signaling pathwayGO:00600701160.018
positive regulation of purine nucleotide catabolic processGO:00331231850.018
stress activated protein kinase signaling cascadeGO:0031098940.018
hemopoiesisGO:00300971800.018
single organism carbohydrate metabolic processGO:00447231930.018
maintenance of locationGO:00512351120.018
innate immune responseGO:00450871780.018
negative regulation of proteolysisGO:00458611320.018
cell growthGO:00160491600.018
protein targetingGO:00066051870.018
tripartite regional subdivisionGO:000735120.018
regulation of ion transportGO:00432691890.018
divalent metal ion transportGO:00708381520.018
regulation of intracellular transportGO:00323861950.017
purine ribonucleotide biosynthetic processGO:0009152790.017
regulation of cell cycle processGO:00105642660.017
nephron tubule formationGO:007207910.017
compound eye developmentGO:004874910.017
cyclic nucleotide biosynthetic processGO:0009190610.017
cellular cation homeostasisGO:00300031630.017
mitochondrion organizationGO:00070051560.017
matingGO:000761810.017
anterior posterior axis specification embryoGO:000859520.017
small molecule biosynthetic processGO:00442831570.017
oocyte differentiationGO:000999420.017
regulation of cytokine productionGO:00018172320.017
inorganic ion transmembrane transportGO:00986602310.017
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.017
adult locomotory behaviorGO:000834410.017
regulation of cell adhesionGO:00301551660.017
microtubule based processGO:00070172100.017
cellular protein complex assemblyGO:00436231880.017
behaviorGO:00076101120.017
regulation of mapk cascadeGO:00434082620.017
positive regulation of cellular component biogenesisGO:00440891580.017
visual behaviorGO:000763220.017
response to radiationGO:00093141510.017
regulation of ras protein signal transductionGO:00465781550.016
motor neuron axon guidanceGO:000804520.016
gtp catabolic processGO:00061842370.016
negative regulation of cellular amine metabolic processGO:003323930.016
response to decreased oxygen levelsGO:0036293960.016
spermatid developmentGO:000728640.016
response to woundingGO:00096111680.016
positive regulation of cell differentiationGO:00455972110.016
regulation of synaptic plasticityGO:004816730.016
guanosine containing compound catabolic processGO:19010692390.016
angiogenesisGO:00015251470.016
proteolysis involved in cellular protein catabolic processGO:00516032440.016
regulation of nucleoside metabolic processGO:00091182090.016
regulation of establishment of protein localizationGO:00702012420.016
regulation of nucleotide catabolic processGO:00308112050.016
nuclear transportGO:00511691790.016
cellular homeostasisGO:00197251960.016
regulation of protein processingGO:00706131500.016
protein oligomerizationGO:00512591730.016
regulation of gtpase activityGO:00430871800.016
posttranscriptional regulation of gene expressionGO:00106082130.016
regulation of gtp catabolic processGO:00331241800.016
regulation of purine nucleotide catabolic processGO:00331212050.016
neurogenesisGO:00220081690.016
developmental programmed cell deathGO:001062330.016
wound healingGO:00420601150.016
epithelial cell differentiationGO:00308551410.016
positive regulation of nucleotide catabolic processGO:00308131850.016
regulation of body fluid levelsGO:0050878990.016
wnt signaling pathwayGO:00160551560.016
protein localization to membraneGO:00726571600.016
oocyte developmentGO:004859910.016
protein ubiquitinationGO:00165673140.015
neuron differentiationGO:00301821380.015
regulation of locomotionGO:00400123290.015
somitogenesisGO:000175620.015
negative regulation of protein processingGO:00109551420.015
positive regulation of digestive system processGO:006045620.015
positive regulation of proteolysisGO:00458621420.015
regulation of cell morphogenesisGO:00226041530.015
regulation of small gtpase mediated signal transductionGO:00510561560.015
negative regulation of phosphorylationGO:00423261740.015
establishment of protein localization to organelleGO:00725941720.015
cell cycle phase transitionGO:00447701730.015
regulation of reactive oxygen species biosynthetic processGO:190342630.015
regulation of protein complex assemblyGO:00432541470.015
negative regulation of cell differentiationGO:00455961710.015
glycoprotein metabolic processGO:00091001100.015
negative regulation of protein maturationGO:19033181420.015
limbic system developmentGO:002176130.015
cellular response to organic cyclic compoundGO:00714071270.015
positive regulation of mapk cascadeGO:00434101900.015
receptor metabolic processGO:0043112810.015
regulation of apoptotic signaling pathwayGO:20012331750.015
regulation of stress activated mapk cascadeGO:0032872840.015
interspecies interaction between organismsGO:00444191560.015
response to growth factorGO:00708482050.015
protein localization to nucleusGO:00345041360.015
regulation of secretionGO:00510461940.015
response to inorganic substanceGO:00100351270.015
rna processingGO:00063962550.015
thymus developmentGO:004853830.015
proteasomal protein catabolic processGO:00104981760.015
single organismal cell cell adhesionGO:00163371480.015
organic hydroxy compound metabolic processGO:19016151470.015
ribose phosphate biosynthetic processGO:0046390820.015
cell substrate adhesionGO:00315891320.015
protein modification by small protein conjugationGO:00324463420.014
pharynx developmentGO:006046510.014
gtp metabolic processGO:00460392390.014
blood vessel developmentGO:00015681720.014
response to nitrogen compoundGO:19016981840.014
phospholipid metabolic processGO:0006644990.014
regulation of cell growthGO:00015581350.014
symbiosis encompassing mutualism through parasitismGO:00444031560.014
reactive nitrogen species metabolic processGO:200105730.014
organic anion transportGO:00157111030.014
canonical wnt signaling pathway involved in cardiac muscle cell fate commitmentGO:006131730.014
glycerolipid metabolic processGO:00464861070.014
positive regulation of cellular component movementGO:00512721810.014
positive regulation of reactive oxygen species metabolic processGO:2000379240.014
metal ion homeostasisGO:00550651690.014
purine containing compound biosynthetic processGO:0072522880.014
divalent inorganic cation homeostasisGO:00725071360.014
epithelial cell proliferationGO:00506731280.014
modification dependent macromolecule catabolic processGO:00436322120.014
ossificationGO:00015031210.014
response to external biotic stimulusGO:00432072610.014
forebrain regionalizationGO:002187130.014
positive regulation of nucleoside metabolic processGO:00459791860.014
chemotaxisGO:00069351570.014
mitotic cell cycle phase transitionGO:00447721620.014
cell part morphogenesisGO:00329901370.014
cell projection assemblyGO:00300311260.014
peptidyl tyrosine modificationGO:00182121700.014
cellular metal ion homeostasisGO:00068751460.014
positive regulation of gtpase activityGO:00435471660.014
sequestering of metal ionGO:0051238240.014
modification dependent protein catabolic processGO:00199412090.014
microtubule cytoskeleton organizationGO:00002261760.014
regulation of axon guidanceGO:190266730.014
endocytosisGO:00068971590.014
sensory perceptionGO:00076001030.014
neuroblast proliferationGO:000740540.014
rhythmic behaviorGO:000762220.014
spinal cord developmentGO:002151040.014
regulation of cyclic nucleotide metabolic processGO:0030799630.014
eye photoreceptor cell differentiationGO:000175420.014
regulation of anatomical structure sizeGO:00900661010.014
long term memoryGO:000761620.013
regulation of mitotic cell cycleGO:00073461890.013
regulation of multi organism processGO:00439001570.013
nerve developmentGO:002167540.013
regulation of immune responseGO:00507762010.013
syncytium formation by plasma membrane fusionGO:000076820.013
stress activated mapk cascadeGO:0051403930.013
negative regulation of transportGO:00510511760.013
regulation of cytoplasmic transportGO:19036491490.013
hemostasisGO:0007599760.013
negative regulation of kinase activityGO:00336731060.013
regulation of ras gtpase activityGO:00323181280.013
ribonucleotide biosynthetic processGO:0009260810.013
cell type specific apoptotic processGO:00972851250.013
embryonic placenta developmentGO:000189210.013
positive regulation of ras gtpase activityGO:00323201170.013
ubiquitin dependent protein catabolic processGO:00065112060.013
embryo developmentGO:00097901230.013
regulation of cell substrate adhesionGO:0010810680.013
regulation of epithelial cell proliferationGO:00506781130.013
ameboidal type cell migrationGO:00016671350.013
regulation of actin cytoskeleton organizationGO:00329561160.013
epithelial cell migrationGO:00106311190.013
positive regulation of protein serine threonine kinase activityGO:00719021190.013
skeletal muscle satellite cell proliferationGO:001484110.013
neurotransmitter secretionGO:000726940.013
regulation of actin filament based processGO:00329701410.013
pattern specification processGO:0007389430.013
regulation of transmembrane transportGO:00347621390.013
protein autophosphorylationGO:00467771230.013
organic hydroxy compound transportGO:0015850630.013
muscle cell fate commitmentGO:004269340.013
ectodermal placode formationGO:006078810.013
cell activationGO:00017752130.013
regulation of wnt signaling pathwayGO:00301111230.013
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.013
myeloid cell differentiationGO:00300991170.013
negative regulation of protein modification processGO:00314002000.013
nucleocytoplasmic transportGO:00069131760.013
negative regulation of transferase activityGO:00513481240.013
regulation of i kappab kinase nf kappab signalingGO:00431221620.013
brain developmentGO:0007420970.013
guanosine containing compound metabolic processGO:19010682440.013
positive regulation of cytokine productionGO:00018191670.013
positive regulation of locomotionGO:00400171860.013
histone modificationGO:00165702510.013
actin mediated cell contractionGO:0070252120.013
circadian behaviorGO:004851220.013
extrinsic apoptotic signaling pathwayGO:00971911190.013
sequestering of calcium ionGO:0051208170.013
regulation of protein transportGO:00512232130.013
positive regulation of neural precursor cell proliferationGO:200017920.013
epithelium migrationGO:00901321190.013
divalent inorganic cation transportGO:00725111580.013
negative regulation of cell adhesionGO:0007162640.012
actin filament based movementGO:0030048170.012
response to hypoxiaGO:0001666960.012
organelle fissionGO:00482851490.012
tissue migrationGO:00901301190.012
coagulationGO:0050817780.012
primary neural tube formationGO:001402030.012
blood coagulationGO:0007596760.012
chromatin organizationGO:00063253510.012
positive regulation of cell adhesionGO:0045785840.012
neural crest cell developmentGO:001403230.012
rostrocaudal neural tube patterningGO:002190310.012
negative regulation of endopeptidase activityGO:0010951840.012
tissue regenerationGO:004224630.012
regulation of bindingGO:00510981110.012
response to organonitrogen compoundGO:00102431560.012
regulation of protein catabolic processGO:00421761550.012
positive regulation of synaptic transmissionGO:005080640.012
cell cell signalingGO:00072671550.012
jnk cascadeGO:0007254800.012
regulation of camp metabolic processGO:0030814520.012
lipid localizationGO:00108761060.012
forebrain generation of neuronsGO:002187230.012
startle responseGO:000196430.012
response to biotic stimulusGO:00096072760.012
regulation of dna metabolic processGO:00510521530.012
regulation of cell activationGO:00508651250.012
cellular response to lipidGO:00713961270.012
endothelial cell migrationGO:0043542860.012
pancreatic juice secretionGO:003015740.012
calcium ion homeostasisGO:00550741220.012
zymogen activationGO:0031638700.012
cellular calcium ion homeostasisGO:00068741170.012
positive regulation of intracellular transportGO:00323881040.012
regulation of map kinase activityGO:00434051080.012
cellular response to nitrogen compoundGO:19016991440.012
negative regulation of cellular component movementGO:00512711060.012
actin filament organizationGO:00070151280.012
cytokine productionGO:00018162470.012
endosomal transportGO:00161971290.012
carboxylic acid biosynthetic processGO:0046394970.012
regulation of cell cycle phase transitionGO:19019871260.012
monocarboxylic acid metabolic processGO:00327871850.012
regulation of stress activated protein kinase signaling cascadeGO:0070302850.012
anion transmembrane transportGO:0098656760.012
regulation of vasculature developmentGO:1901342970.012
brain morphogenesisGO:004885410.012
cell divisionGO:00513011680.012
regulation of erk1 and erk2 cascadeGO:0070372990.012
stem cell divisionGO:001714520.012
positive regulation of secretion by cellGO:19035321080.012
i kappab kinase nf kappab signalingGO:00072491660.011
regulation of hormone levelsGO:00108171250.011
purine ribonucleoside monophosphate metabolic processGO:00091671860.011
negative regulation of protein phosphorylationGO:00019331400.011
positive regulation of endopeptidase activityGO:0010950840.011
negative regulation of cell cycleGO:00457861930.011
cerebellum developmentGO:002154920.011
activation of protein kinase activityGO:0032147900.011

APLN disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
sensory system diseaseDOID:00501552030.034
nervous system diseaseDOID:8634310.034
eye and adnexa diseaseDOID:14921500.027
eye diseaseDOID:56141490.027
central nervous system diseaseDOID:3311860.025
disease of cellular proliferationDOID:145661740.019
retinal diseaseDOID:56791180.019
cancerDOID:1621670.018
organ system cancerDOID:00506861640.018
disease of metabolismDOID:00146672950.017
musculoskeletal system diseaseDOID:172230.016
connective tissue diseaseDOID:651090.015
cardiovascular system diseaseDOID:12871060.013
retinal degenerationDOID:8466890.013
auditory system diseaseDOID:2742530.013
neurodegenerative diseaseDOID:12891020.012
inherited metabolic disorderDOID:6552420.012