Homo sapiens

72 known processes

MAPK1

mitogen-activated protein kinase 1

(Aliases: ERK2,p41mapk,PRKM2,PRKM1,MAPK2,p38,P42MAPK,p40,ERT1,p41,ERK)

MAPK1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
response to nitrosative stressGO:005140941.000
jun phosphorylationGO:0007258281.000
Fly
transposition rna mediatedGO:003219701.000
Yeast
inactivation of mapk activityGO:000018851.000
negative regulation of erk1 and erk2 cascadeGO:0070373141.000
peptidyl tyrosine dephosphorylationGO:0035335361.000
regulation of erk1 and erk2 cascadeGO:0070372991.000
Human Fly
ras protein signal transductionGO:0007265731.000
Worm Fly
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691811.000
negative regulation of protein serine threonine kinase activityGO:0071901571.000
dephosphorylationGO:00163112091.000
protein dephosphorylationGO:0006470811.000
erk1 and erk2 cascadeGO:00703711041.000
regulation of map kinase activityGO:00434051081.000
negative regulation of catalytic activityGO:00430863351.000
negative regulation of map kinase activityGO:0043407271.000
mapk cascadeGO:00001652880.999
negative regulation of phosphate metabolic processGO:00459362670.999
Yeast
regulation of ras protein signal transductionGO:00465781550.999
Fly
small gtpase mediated signal transductionGO:0007264780.999
Worm Fly
signal transduction by phosphorylationGO:00230142970.999
regulation of protein serine threonine kinase activityGO:00719001790.999
negative regulation of phosphorylationGO:00423261740.999
Yeast
mapk import into nucleusGO:000018910.998
Rat
arachidonic acid metabolic processGO:0019369140.998
negative regulation of mapk cascadeGO:0043409560.998
Yeast
regulation of mapk cascadeGO:00434082620.997
Human Yeast Fly
peptidyl threonine phosphorylationGO:0018107410.997
stress activated protein kinase signaling cascadeGO:0031098940.996
Fly
negative regulation of small gtpase mediated signal transductionGO:0051058120.995
oogenesisGO:004847720.995
Worm
immune response regulating signaling pathwayGO:0002764970.994
Mouse
positive regulation of apoptotic processGO:00430652460.994
negative regulation of transpositionGO:001052970.994
Yeast
positive regulation of protein phosphorylationGO:00019343130.993
negative regulation of phosphorus metabolic processGO:00105632670.992
Yeast
enzyme linked receptor protein signaling pathwayGO:00071673030.992
negative regulation of protein phosphorylationGO:00019331400.991
negative regulation of protein metabolic processGO:00512483910.991
protein localization to organelleGO:00333652800.990
Rat
chordate embryonic developmentGO:0043009340.989
Mouse
mitotic cell cycleGO:00002783260.989
Worm Fly
peptidyl serine phosphorylationGO:00181051010.988
hyperosmotic responseGO:000697240.987
negative regulation of cellular protein metabolic processGO:00322693530.986
regulation of protein kinase activityGO:00458592890.986
regulation of peptidase activityGO:00525471800.984
cytoplasmic transportGO:00164823790.983
Yeast Rat
synaptic transmissionGO:0007268610.979
Fly
regulation of protein localizationGO:00328802960.979
Yeast
cell cycle arrestGO:0007050710.978
Yeast
negative regulation of transferase activityGO:00513481240.976
response to abiotic stimulusGO:00096283360.974
Human
cellular amine metabolic processGO:0044106410.971
tor signalingGO:0031929390.970
establishment of protein localization to organelleGO:00725941720.970
Rat
regulation of small gtpase mediated signal transductionGO:00510561560.969
Fly
positive regulation of cellular amine metabolic processGO:003324070.969
photoreceptor cell differentiationGO:004653020.967
Fly
negative regulation of ras protein signal transductionGO:0046580110.961
regulation of cell motilityGO:20001452990.961
Rat
cartilage condensationGO:000150210.961
negative regulation of apoptotic processGO:00430663160.952
response to molecule of bacterial originGO:0002237820.951
Mouse
behavioral response to ethanolGO:004814920.951
Fly
positive regulation of cellular amino acid metabolic processGO:004576430.950
histone phosphorylationGO:0016572160.949
Human
positive regulation of programmed cell deathGO:00430682490.949
macroautophagyGO:0016236390.947
Fly
long chain fatty acid metabolic processGO:0001676300.946
regulation of transferase activityGO:00513383550.944
regulation of kinase activityGO:00435493140.942
cell junction maintenanceGO:003433140.941
Fly
activation of mapk activityGO:0000187450.938
negative regulation of intracellular signal transductionGO:19025321830.938
Yeast
apoptotic signaling pathwayGO:00971902680.936
negative regulation of protein kinase activityGO:0006469980.934
regulation of cell cycleGO:00517263930.933
Yeast Worm
negative regulation of cell cycleGO:00457861930.928
Yeast Worm
p38mapk cascadeGO:003806690.924
response to growth factorGO:00708482050.924
negative regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043154460.924
negative regulation of response to external stimulusGO:0032102830.921
Fly
positive regulation of apoptotic signaling pathwayGO:2001235700.921
negative regulation of macroautophagyGO:001624240.911
Fly
peptidyl lysine acetylationGO:00183941010.910
Human
lipid metabolic processGO:00066293810.903
determination of adult lifespanGO:000834020.901
Worm
oocyte developmentGO:004859910.900
Worm
protein catabolic processGO:00301633250.898
Worm
peptidyl serine modificationGO:00182091060.895
positive regulation of histone phosphorylationGO:003312930.891
Human
female gamete generationGO:000729220.889
Worm
neuron differentiationGO:00301821380.886
Fly
positive regulation of mapk cascadeGO:00434101900.886
Human Fly
single organism cellular localizationGO:19025803320.884
Rat
positive regulation of phosphorylationGO:00423273940.880
cellular response to cytokine stimulusGO:00713451810.880
Human Mouse
interleukin 1 mediated signaling pathwayGO:0070498120.874
Human
histone h2a s1 phosphorylationGO:004399010.869
regulation of stress activated mapk cascadeGO:0032872840.867
regulation of jnk cascadeGO:0046328730.864
nucleocytoplasmic transportGO:00069131760.863
Yeast Rat
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781250.857
Human
negative regulation of kinase activityGO:00336731060.855
cell cell signalingGO:00072671550.851
Fly
organelle inheritanceGO:004830820.851
post embryonic developmentGO:000979120.838
Worm Fly
regulation of nucleocytoplasmic transportGO:0046822980.837
Yeast
regulation of histone phosphorylationGO:003312750.827
Human
regulation of transpositionGO:001052870.827
Yeast
immune responseGO:00069553070.818
Mouse
response to lipidGO:00339932060.816
Mouse Rat
regulation of protein transportGO:00512232130.808
Yeast
response to cytokineGO:00340972320.805
Human Mouse
regulation of cellular ketone metabolic processGO:0010565500.804
purine ribonucleotide catabolic processGO:00091544040.798
system processGO:00030083490.793
Rat
cellular response to abiotic stimulusGO:00712141170.789
Human
regulation of cellular response to stressGO:00801352440.786
Fly
muscle system processGO:0003012810.780
response to external biotic stimulusGO:00432072610.775
Mouse
dna damage response signal transduction by p53 class mediatorGO:0030330440.774
epithelium migrationGO:00901321190.772
response to salt stressGO:000965130.772
negative regulation of cell migrationGO:00303361020.771
cellular amino acid metabolic processGO:00065201160.770
nuclear transportGO:00511691790.770
Yeast Rat
cellular response to metal ionGO:0071248430.762
Fly
amine metabolic processGO:0009308440.756
nervous system developmentGO:00073992930.749
Fly
regulation of mitotic cell cycleGO:00073461890.747
Worm
cell activationGO:00017752130.740
negative regulation of protein processingGO:00109551420.735
activation of protein kinase activityGO:0032147900.734
positive regulation of cell deathGO:00109422630.725
histone serine phosphorylationGO:003540440.719
cellular response to external stimulusGO:00714961110.719
Human Fly
stress activated mapk cascadeGO:0051403930.717
Fly
activation of immune responseGO:00022531140.714
Mouse
protein importGO:00170381300.709
Rat
multicellular organismal agingGO:001025930.706
Worm
negative regulation of apoptotic signaling pathwayGO:2001234970.706
response to woundingGO:00096111680.702
Fly
peptidyl tyrosine phosphorylationGO:00181081700.702
Human
mucosal immune responseGO:0002385210.701
response to metal ionGO:0010038840.700
Fly
response to nitrogen compoundGO:19016981840.692
Mouse
protein targetingGO:00066051870.687
Rat
regulation of immune responseGO:00507762010.687
Mouse
defense responseGO:00069523150.685
cell aggregationGO:009874310.679
fatty acid metabolic processGO:00066311150.674
positive regulation of organelle organizationGO:00106381950.668
Human
jnk cascadeGO:0007254800.660
Fly
peptidyl tyrosine modificationGO:00182121700.660
Human
regulation of cellular amine metabolic processGO:0033238110.659
protein maturationGO:00516042330.655
intracellular protein transportGO:00068862700.654
Yeast Rat
endomembrane system organizationGO:00102561960.649
paracrine signalingGO:003800110.645
growthGO:00400072020.642
Yeast
positive regulation of cell cycleGO:00457871400.638
Worm
innate immune responseGO:00450871780.638
tissue migrationGO:00901301190.637
cellular response to growth factor stimulusGO:00713631970.636
regulation of cellular amino acid metabolic processGO:000652160.636
nuclear divisionGO:00002801280.627
Fly
regulation of chromatin organizationGO:1902275560.624
Human
regulation of peptidyl lysine acetylationGO:2000756220.617
Human
chromatin modificationGO:00165682980.611
Human
negative regulation of extrinsic apoptotic signaling pathway via death domain receptorsGO:1902042150.609
negative regulation of protein modification processGO:00314002000.608
regulation of cysteine type endopeptidase activityGO:20001161270.606
skeletal system developmentGO:0001501790.599
cellular response to interleukin 1GO:0071347350.598
Human
regulation of apoptotic signaling pathwayGO:20012331750.597
negative regulation of stress activated protein kinase signaling cascadeGO:0070303190.597
regulation of protein export from nucleusGO:0046825150.594
Yeast
regulation of cytoplasmic transportGO:19036491490.593
Yeast
regulation of defense responseGO:00313471540.592
regulation of intracellular transportGO:00323861950.584
Yeast
regulation of protein acetylationGO:1901983250.583
Human
regulation of protein maturationGO:19033171500.582
tube morphogenesisGO:0035239950.578
Zebrafish
response to toxic substanceGO:0009636370.576
Rat
cellular ketone metabolic processGO:0042180800.575
positive regulation of hydrolase activityGO:00513453310.574
positive regulation of map kinase activityGO:0043406800.573
extrinsic apoptotic signaling pathwayGO:00971911190.572
regulation of multi organism processGO:00439001570.572
dna damage induced protein phosphorylationGO:000697550.571
Human
positive regulation of wound healingGO:0090303200.568
Fly
cellular response to dna damage stimulusGO:00069743790.568
Human Mouse Fly
response to extracellular stimulusGO:0009991850.568
Fly
lipopolysaccharide mediated signaling pathwayGO:0031663260.564
Mouse
mitotic nuclear divisionGO:00070671190.562
Fly
single organism nuclear importGO:19025931040.561
Rat
negative regulation of mitotic cell cycleGO:00459301020.561
Worm
negative regulation of jnk cascadeGO:0046329160.559
response to mechanical stimulusGO:0009612510.558
Human
cellular senescenceGO:0090398340.554
innate immune response activating signal transductionGO:0002758480.549
regulation of autophagyGO:0010506520.546
Fly
positive regulation of transportGO:00510503360.546
Yeast
histone modificationGO:00165702510.536
Human
response to inorganic substanceGO:00100351270.533
Fly
cardiovascular system developmentGO:00723582620.516
Mouse
blood vessel developmentGO:00015681720.513
Mouse
mitotic cell cycle processGO:19030472860.512
Fly
positive regulation of intracellular protein transportGO:0090316760.511
Yeast
positive regulation of extrinsic apoptotic signaling pathwayGO:2001238260.511
regulation of response to woundingGO:19030341010.506
Fly
positive regulation of protein kinase activityGO:00458601900.503
chromatin organizationGO:00063253510.501
Human
regulation of endopeptidase activityGO:00525481700.498
negative regulation of hydrolase activityGO:00513461820.496
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.496
embryo development ending in birth or egg hatchingGO:0009792340.494
Mouse Worm
cell morphogenesisGO:00009022960.492
developmental growthGO:0048589480.492
dna replicationGO:00062601160.487
single organismal cell cell adhesionGO:00163371480.487
tripartite regional subdivisionGO:000735120.486
regulation of muscle system processGO:0090257530.480
protein localization to nucleusGO:00345041360.471
Rat
icosanoid metabolic processGO:0006690350.468
immune response regulating cell surface receptor signaling pathwayGO:0002768510.462
Mouse
peroxisome degradationGO:003024210.462
positive regulation of cytoplasmic transportGO:1903651820.456
Yeast
regulation of epithelial cell migrationGO:0010632930.455
response to osmotic stressGO:0006970170.454
protein targeting to nucleusGO:00447441040.451
Rat
negative regulation of programmed cell deathGO:00430693210.448
mrna stabilizationGO:0048255180.444
regulation of intracellular protein transportGO:00331571230.443
Yeast
regenerationGO:003109940.443
positive regulation of transferase activityGO:00513472270.442
fatty acid derivative metabolic processGO:1901568350.439
regulation of sequence specific dna binding transcription factor activityGO:00510902110.437
Yeast
regulation of response to osmotic stressGO:004748430.436
cytokine mediated signaling pathwayGO:00192211090.435
Human
negative regulation of cell deathGO:00605483450.434
mapk export from nucleusGO:004520410.426
negative regulation of protein maturationGO:19033181420.414
negative regulation of immune system processGO:00026831360.413
regulation of protein localization to plasma membraneGO:1903076400.413
response to biotic stimulusGO:00096072760.412
Mouse
cell adhesionGO:00071553250.410
organ morphogenesisGO:00098871470.410
Mouse Fly
placenta developmentGO:0001890100.409
Mouse
sensory perception of painGO:001923340.408
Rat
associative learningGO:000830610.407
positive regulation of cell developmentGO:0010720920.407
Fly
translational initiationGO:0006413480.406
regulation of anatomical structure sizeGO:00900661010.406
cytoskeleton dependent intracellular transportGO:0030705210.404
regulation of locomotionGO:00400123290.389
Rat
regulation of chromosome organizationGO:00330441030.388
Human
regulation of proteolysisGO:00301622930.385
response to light stimulusGO:0009416870.382
positive regulation of defense responseGO:0031349870.381
positive regulation of chromatin modificationGO:1903310300.380
Human
unsaturated fatty acid metabolic processGO:0033559370.380
skeletal muscle tissue regenerationGO:004340320.379
positive regulation of neurogenesisGO:0050769490.378
Fly
response to bacteriumGO:00096171440.376
Mouse
regulation of killing of cells of other organismGO:005170940.376
cellular component morphogenesisGO:00329893140.375
negative regulation of peptidase activityGO:0010466910.373
cellular lipid metabolic processGO:00442553030.372
cellular response to nitrogen compoundGO:19016991440.370
transmission of nerve impulseGO:0019226110.370
regulation of protein targetingGO:1903533910.370
positive regulation of meiotic cell cycleGO:005144620.365
Worm
embryo developmentGO:00097901230.365
Zebrafish Mouse Worm
positive regulation of cell differentiationGO:00455972110.363
Fly
negative regulation of stress activated mapk cascadeGO:0032873190.361
positive regulation of immune responseGO:00507781590.357
Mouse
tissue morphogenesisGO:0048729960.353
positive regulation of neuron differentiationGO:0045666400.352
Fly
defense response to other organismGO:00985421290.347
cellular response to lipidGO:00713961270.346
Mouse
positive regulation of erk1 and erk2 cascadeGO:0070374750.344
Human Fly
behaviorGO:00076101120.342
Fly
regulation of neuron differentiationGO:0045664700.340
Fly
response to other organismGO:00517072610.338
Mouse
anterior posterior axis specification embryoGO:000859520.335
response to hormoneGO:00097251750.335
Rat
regulation of dephosphorylationGO:0035303960.333
cellular homeostasisGO:00197251960.332
internal peptidyl lysine acetylationGO:0018393970.330
Human
positive regulation of developmental processGO:00510943140.330
Fly
signal transduction in response to dna damageGO:0042770570.329
regulation of cellular component movementGO:00512703340.326
Rat
positive regulation of protein export from nucleusGO:004682760.324
Yeast
regulation of translationGO:0006417890.317
Rat
protein autophosphorylationGO:00467771230.316
Human Yeast
cell cell junction organizationGO:0045216690.316
Fly
cellular response to reactive oxygen speciesGO:0034614500.311
Fly
cellular macromolecular complex assemblyGO:00346223240.310
developmental process involved in reproductionGO:0003006660.308
Mouse Worm
autophagyGO:0006914880.308
Fly
circulatory system developmentGO:00723592620.308
Mouse
negative regulation of t cell receptor signaling pathwayGO:005086040.307
response to axon injuryGO:004867810.303
regulation of hepatic stellate cell activationGO:200048910.300
apoptotic mitochondrial changesGO:0008637570.297
immune response activating signal transductionGO:0002757900.291
Mouse
actin filament based processGO:00300292240.291
pattern recognition receptor signaling pathwayGO:0002221480.290
embryonic placenta developmentGO:000189210.289
Mouse
purine ribonucleoside triphosphate metabolic processGO:00092054110.288
negative regulation of catabolic processGO:00098951040.284
Fly
wound healingGO:00420601150.282
Fly
t cell receptor signaling pathwayGO:0050852210.279
Mouse
regulation of response to drugGO:200102330.279
Fly
signal transduction by p53 class mediatorGO:0072331720.277
central nervous system neuron axonogenesisGO:002195530.276
posttranscriptional regulation of gene expressionGO:00106082130.271
Rat
single organism cell adhesionGO:00986021790.270
regulation of protein polymerizationGO:0032271630.269
regulation of cell differentiationGO:00455953930.269
Mouse Fly
cell agingGO:0007569520.269
generation of neuronsGO:00486991520.267
Fly
response to interleukin 1GO:0070555470.264
Human
translationGO:00064121320.264
Rat
cellular response to organonitrogen compoundGO:00714171240.262
regulation of neurogenesisGO:0050767820.259
Fly
regulation of antigen receptor mediated signaling pathwayGO:0050854100.258
positive regulation of protein serine threonine kinase activityGO:00719021190.257
brain developmentGO:0007420970.257
cellular response to inorganic substanceGO:0071241450.253
Fly
regulation of wound healingGO:0061041560.246
Fly
microtubule based processGO:00070172100.244
regulation of cell developmentGO:00602841610.243
Fly
regulation of protein processingGO:00706131500.241
negative regulation of cellular catabolic processGO:0031330830.237
Fly
carbohydrate transportGO:0008643370.236
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280690.235
response to radiationGO:00093141510.235
heart developmentGO:0007507950.234
positive regulation of ras gtpase activityGO:00323201170.228
positive regulation of nucleocytoplasmic transportGO:0046824540.227
Yeast
tissue regenerationGO:004224630.227
regulation of histone acetylationGO:0035065190.224
Human
regulation of cytokine productionGO:00018172320.224
neurological system processGO:00508771630.218
Rat
negative regulation of cellular component movementGO:00512711060.216
cartilage developmentGO:0051216310.216
regulation of syncytium formation by plasma membrane fusionGO:006014220.214
regulation of meiotic cell cycleGO:005144540.210
Worm
regulation of mitotic cell cycle phase transitionGO:19019901180.209
pattern specification processGO:0007389430.208
Fly
response to temperature stimulusGO:0009266220.203
cellular response to hormone stimulusGO:00328701250.202
release of cytochrome c from mitochondriaGO:0001836350.200
cellular response to endogenous stimulusGO:00714953360.199
negative regulation of response to extracellular stimulusGO:003210550.199
Fly
response to insulinGO:0032868450.198
response to tumor necrosis factorGO:0034612760.198
foam cell differentiationGO:0090077150.197
regulation of protein complex assemblyGO:00432541470.196
microtubule based movementGO:0007018320.196
negative regulation of endopeptidase activityGO:0010951840.195
protein oligomerizationGO:00512591730.193
sensory perceptionGO:00076001030.192
Rat
ribonucleotide catabolic processGO:00092614050.191
negative regulation of multicellular organismal processGO:00512413170.187
Worm
ameboidal type cell migrationGO:00016671350.185
regulation of protein bindingGO:0043393660.181
pigmentationGO:0043473220.180
cellular response to starvationGO:0009267580.178
Fly
positive regulation of cellular component biogenesisGO:00440891580.178
positive regulation of small gtpase mediated signal transductionGO:0051057120.177
Fly
circadian behaviorGO:004851220.176
organelle assemblyGO:00709251760.175
negative regulation of organelle organizationGO:00106391260.172
positive regulation of growthGO:0045927580.170
single organism reproductive processGO:0044702980.169
Mouse Worm
centrosome separationGO:005129930.169
regulation of stress activated protein kinase signaling cascadeGO:0070302850.169
meiotic chromosome segregationGO:004513240.169
cellular response to nutrient levelsGO:0031669690.168
Fly
positive regulation of organic acid transportGO:003289230.168
regulation of innate immune responseGO:0045088970.168
antigen receptor mediated signaling pathwayGO:0050851380.167
Mouse
positive regulation of intracellular transportGO:00323881040.165
Yeast
negative regulation of bindingGO:0051100570.160
cellular hyperosmotic responseGO:007147440.159
neuron projection developmentGO:00311751060.157
response to cadmium ionGO:0046686100.157
Fly
blastoderm segmentationGO:000735020.156
regulation of nervous system developmentGO:0051960880.154
Fly
negative regulation of cell adhesionGO:0007162640.154
negative regulation of cell proliferationGO:00082852280.152
response to uvGO:0009411730.152
actin filament cappingGO:005169340.150
positive regulation of histone acetylationGO:0035066110.150
Human
peptidyl serine autophosphorylationGO:003628920.148
positive regulation of kinase activityGO:00336742040.148
defense response to fungusGO:005083240.148
covalent chromatin modificationGO:00165692540.147
Human
circulatory system processGO:00030131130.147
agingGO:0007568660.146
Worm
anatomical structure formation involved in morphogenesisGO:00486462840.146
extrinsic apoptotic signaling pathway via death domain receptorsGO:0008625420.146
regulation of cell killingGO:0031341220.145
positive regulation of multi organism processGO:0043902560.145
segmentationGO:003528240.145
protein import into nucleusGO:00066061040.144
Rat
cell type specific apoptotic processGO:00972851250.141
histone acetylationGO:0016573930.138
Human
protein acetylationGO:00064731160.138
Human
regulation of dna metabolic processGO:00510521530.137
membrane organizationGO:00610242920.135
cell growthGO:00160491600.135
negative regulation of locomotionGO:00400131180.134
negative regulation of cell cycle processGO:00109481210.134
t cell activationGO:0042110990.134
positive regulation of chromosome organizationGO:2001252410.132
Human
intrinsic apoptotic signaling pathwayGO:00971931270.132
response to oxidative stressGO:00069791210.131
Fly
negative regulation of protein polymerizationGO:0032272160.130
actin polymerization or depolymerizationGO:0008154560.130
regulation of secretionGO:00510461940.130
positive regulation of cellular component organizationGO:00511303760.129
Human
nuclear exportGO:0051168690.129
Yeast
establishment of protein localization to membraneGO:00901501210.128
reproductionGO:0000003630.127
Yeast Worm
cytosolic calcium ion homeostasisGO:0051480890.126
response to nutrient levelsGO:0031667810.122
Fly
protein acylationGO:00435431380.121
Human
negative regulation of intracellular transportGO:0032387600.120
striated muscle tissue developmentGO:0014706590.119
regulation of rho protein signal transductionGO:0035023790.118
regulation of developmental pigmentationGO:004807020.116
regulation of establishment of protein localizationGO:00702012420.115
Yeast
positive regulation of sequence specific dna binding transcription factor activityGO:00510911310.115
regulation of extrinsic apoptotic signaling pathwayGO:2001236850.115
regulation of protein localization to nucleusGO:1900180850.112
neuromuscular junction developmentGO:000752830.111
dna damage response signal transduction resulting in transcriptionGO:0042772120.111
morphogenesis of embryonic epitheliumGO:001633140.111
negative regulation of protein complex assemblyGO:0031333430.109
regulation of anatomical structure morphogenesisGO:00226032860.109
oocyte differentiationGO:000999420.108
Worm
nuclear importGO:00511701060.107
Rat
positive regulation of mitotic cell cycleGO:0045931600.107
muscle tissue developmentGO:0060537620.107
response to alcoholGO:0097305640.106
Fly
positive regulation of cell motilityGO:20001471770.104
Rat
neuron developmentGO:00486661130.103
regulation of protein import into nucleusGO:0042306780.102
positive regulation of catabolic processGO:00098963100.101
regulation of macroautophagyGO:0016241190.100
Fly
response to organic cyclic compoundGO:00140702040.100
Mouse Rat
negative regulation of autophagyGO:0010507140.099
Fly
cell developmentGO:00484683280.099
Worm Fly
positive regulation of gtp catabolic processGO:00331261660.098
regulation of glucose importGO:0046324210.098
cation homeostasisGO:00550801890.097
negative regulation of homotypic cell cell adhesionGO:003411130.096
negative regulation of mitotic cell cycle phase transitionGO:1901991850.095
response to organonitrogen compoundGO:00102431560.094
purine nucleoside catabolic processGO:00061523980.094
regulation of growthGO:00400081650.093
cellular response to molecule of bacterial originGO:0071219620.093
Mouse
glycosyl compound catabolic processGO:19016584130.093
central nervous system neuron developmentGO:002195470.092
histone h2a phosphorylationGO:199016430.092
developmental programmed cell deathGO:001062330.092
cellular response to lipopolysaccharideGO:0071222570.091
Mouse
regulation of cytoskeleton organizationGO:00514931770.091
microtubule based transportGO:0010970210.090
proteolysis involved in cellular protein catabolic processGO:00516032440.090
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092900.089
negative regulation of proteolysisGO:00458611320.089
cellular response to osmotic stressGO:007147080.089
regulation of protein dephosphorylationGO:0035304180.089
regulation of extrinsic apoptotic signaling pathway via death domain receptorsGO:1902041240.088
axon developmentGO:0061564340.088
lipid biosynthetic processGO:00086101770.088
regulation of ras gtpase activityGO:00323181280.087
cellular response to oxidative stressGO:0034599850.086
Fly
rho protein signal transductionGO:0007266260.086
biological adhesionGO:00226103310.085
gtp metabolic processGO:00460392390.085
protein localization to plasma membraneGO:0072659930.084

MAPK1 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
cancerDOID:1621670.632
disease of cellular proliferationDOID:145661740.632
non syndromic intellectual disabilityDOID:005088990.246
disease of mental healthDOID:150700.246
developmental disorder of mental healthDOID:0060037290.246
specific developmental disorderDOID:0060038190.246
non specific x linked mental retardationDOID:005077670.246
intellectual disabilityDOID:1059130.246