Homo sapiens

110 known processes

PLCE1

phospholipase C, epsilon 1

(Aliases: MGC167842,PPLC,PLCE,KIAA1516,FLJ23659,NPHS3)

PLCE1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
small gtpase mediated signal transductionGO:0007264780.208
rho protein signal transductionGO:0007266260.135
positive regulation of hydrolase activityGO:00513453310.128
post embryonic developmentGO:000979120.127
purine nucleotide catabolic processGO:00061954050.124
purine ribonucleotide catabolic processGO:00091544040.123
purine nucleoside catabolic processGO:00061523980.119
nucleoside phosphate catabolic processGO:19012924120.118
purine containing compound catabolic processGO:00725234110.118
glycosyl compound catabolic processGO:19016584130.113
organophosphate catabolic processGO:00464344300.108
purine ribonucleoside metabolic processGO:00461284370.102
purine ribonucleoside triphosphate catabolic processGO:00092073910.101
purine ribonucleoside triphosphate metabolic processGO:00092054110.099
purine ribonucleoside catabolic processGO:00461303980.096
nucleoside triphosphate metabolic processGO:00091414220.092
nucleoside catabolic processGO:00091644080.092
ras protein signal transductionGO:0007265730.092
ribonucleoside triphosphate metabolic processGO:00091994120.089
cellular component morphogenesisGO:00329893140.087
negative regulation of developmental processGO:00510932470.087
purine nucleoside triphosphate catabolic processGO:00091463920.087
nucleoside triphosphate catabolic processGO:00091433940.087
positive regulation of catabolic processGO:00098963100.087
ribonucleoside triphosphate catabolic processGO:00092033910.084
nucleotide catabolic processGO:00091664080.084
regulation of locomotionGO:00400123290.084
regulation of cellular amine metabolic processGO:0033238110.082
cell developmentGO:00484683280.081
purine nucleoside triphosphate metabolic processGO:00091444120.080
ribonucleoside catabolic processGO:00424544060.080
regulation of cell motilityGO:20001452990.079
anatomical structure formation involved in morphogenesisGO:00486462840.079
positive regulation of nucleotide catabolic processGO:00308131850.078
mapk cascadeGO:00001652880.077
regulation of cellular component movementGO:00512703340.077
regulation of purine nucleotide metabolic processGO:19005422640.076
regulation of gtp catabolic processGO:00331241800.076
regulation of nucleoside metabolic processGO:00091182090.075
positive regulation of cellular catabolic processGO:00313312840.075
gtp catabolic processGO:00061842370.074
guanosine containing compound metabolic processGO:19010682440.073
positive regulation of purine nucleotide metabolic processGO:19005442270.073
cellular ketone metabolic processGO:0042180800.072
regulation of cellular amino acid metabolic processGO:000652160.071
regulation of nucleotide metabolic processGO:00061402690.071
circulatory system developmentGO:00723592620.071
positive regulation of nucleoside metabolic processGO:00459791860.070
regulation of cell differentiationGO:00455953930.070
regulation of nucleotide catabolic processGO:00308112050.070
amine metabolic processGO:0009308440.069
regulation of ras protein signal transductionGO:00465781550.068
gtp metabolic processGO:00460392390.068
nervous system developmentGO:00073992930.068
positive regulation of gtpase activityGO:00435471660.067
oogenesisGO:004847720.067
cellular amino acid metabolic processGO:00065201160.066
cellular amine metabolic processGO:0044106410.066
regulation of purine nucleotide catabolic processGO:00331212050.065
cell projection organizationGO:00300302520.065
female gamete generationGO:000729220.064
ribonucleotide catabolic processGO:00092614050.063
actin filament based processGO:00300292240.063
regulation of cellular ketone metabolic processGO:0010565500.063
cardiovascular system developmentGO:00723582620.063
positive regulation of protein phosphorylationGO:00019343130.062
regulation of cellular component biogenesisGO:00440872810.062
positive regulation of phosphorylationGO:00423273940.061
positive regulation of gtp catabolic processGO:00331261660.061
cell fate determinationGO:000170930.060
cytoplasmic transportGO:00164823790.059
positive regulation of locomotionGO:00400171860.059
regulation of small gtpase mediated signal transductionGO:00510561560.059
cell morphogenesisGO:00009022960.059
establishment or maintenance of bipolar cell polarityGO:006124520.059
positive regulation of cellular amino acid metabolic processGO:004576430.058
regulation of anatomical structure morphogenesisGO:00226032860.058
system processGO:00030083490.058
regulation of gtpase activityGO:00430871800.058
negative regulation of multicellular organismal processGO:00512413170.057
guanosine containing compound catabolic processGO:19010692390.057
signal transduction by phosphorylationGO:00230142970.055
regulation of mapk cascadeGO:00434082620.054
vasculature developmentGO:00019441810.054
enzyme linked receptor protein signaling pathwayGO:00071673030.054
negative regulation of cell proliferationGO:00082852280.053
peripheral nervous system developmentGO:000742220.052
positive regulation of cellular component organizationGO:00511303760.052
regulation of transferase activityGO:00513383550.052
positive regulation of ras gtpase activityGO:00323201170.051
regulation of protein kinase activityGO:00458592890.051
regulation of cell migrationGO:00303342890.051
positive regulation of cellular amine metabolic processGO:003324070.051
positive regulation of cell proliferationGO:00082843010.050
regulation of kinase activityGO:00435493140.049
regulation of cell cycleGO:00517263930.048
establishment or maintenance of apical basal cell polarityGO:003508820.048
negative regulation of phosphorus metabolic processGO:00105632670.047
positive regulation of nucleotide metabolic processGO:00459812300.047
blood vessel morphogenesisGO:00485141620.047
positive regulation of mapk cascadeGO:00434101900.047
blood vessel developmentGO:00015681720.046
photoreceptor cell differentiationGO:004653020.046
multicellular organismal agingGO:001025930.046
cyclic nucleotide metabolic processGO:0009187820.045
cell morphogenesis involved in differentiationGO:00009041440.045
negative regulation of phosphate metabolic processGO:00459362670.045
positive regulation of developmental processGO:00510943140.045
negative regulation of cell deathGO:00605483450.044
negative regulation of catalytic activityGO:00430863350.044
cell adhesionGO:00071553250.044
protein localization to organelleGO:00333652800.043
negative regulation of programmed cell deathGO:00430693210.043
regulation of protein serine threonine kinase activityGO:00719001790.043
angiogenesisGO:00015251470.042
growthGO:00400072020.042
neuromuscular junction developmentGO:000752830.042
organophosphate biosynthetic processGO:00904071630.042
lipid metabolic processGO:00066293810.041
actin cytoskeleton organizationGO:00300362070.041
chemotaxisGO:00069351570.041
secretionGO:00469032540.041
locomotory behaviorGO:000762610.041
taxisGO:00423301570.041
oocyte differentiationGO:000999420.040
regulation of cytoskeleton organizationGO:00514931770.040
response to oxygen containing compoundGO:19017003690.040
epithelium developmentGO:00604292270.040
positive regulation of cell migrationGO:00303351720.040
determination of adult lifespanGO:000834020.039
regulation of protein localizationGO:00328802960.039
regulation of cellular response to stressGO:00801352440.039
regulation of ras gtpase activityGO:00323181280.039
biological adhesionGO:00226103310.039
regulation of cell developmentGO:00602841610.038
neuron differentiationGO:00301821380.038
g protein coupled receptor signaling pathwayGO:00071862070.037
oocyte developmentGO:004859910.037
tube developmentGO:00352951250.037
mitotic cell cycleGO:00002783260.037
carbohydrate derivative biosynthetic processGO:19011372070.037
vesicle mediated transportGO:00161923710.037
generation of neuronsGO:00486991520.037
cellular response to endogenous stimulusGO:00714953360.037
regulation of cell cycle processGO:00105642660.036
compound eye developmentGO:004874910.036
muscle structure developmentGO:0061061980.036
positive regulation of transferase activityGO:00513472270.036
single organism cellular localizationGO:19025803320.036
apoptotic signaling pathwayGO:00971902680.035
osteoblast differentiationGO:0001649920.035
segmentationGO:003528240.035
mitotic cell cycle processGO:19030472860.035
regulation of epithelial cell proliferationGO:00506781130.035
positive regulation of cell differentiationGO:00455972110.035
positive regulation of kinase activityGO:00336742040.035
cellular lipid metabolic processGO:00442553030.035
intracellular protein transportGO:00068862700.034
negative regulation of protein metabolic processGO:00512483910.034
negative regulation of cellular component organizationGO:00511292350.034
regulation of actin filament based processGO:00329701410.034
regulation of growthGO:00400081650.034
cell projection assemblyGO:00300311260.033
regulation of actin cytoskeleton organizationGO:00329561160.033
cellular response to oxygen containing compoundGO:19017012760.033
negative regulation of cell cycleGO:00457861930.033
negative regulation of hydrolase activityGO:00513461820.033
chemical homeostasisGO:00488783060.033
immune responseGO:00069553070.033
stress activated protein kinase signaling cascadeGO:0031098940.033
positive regulation of purine nucleotide catabolic processGO:00331231850.032
positive regulation of cellular component movementGO:00512721810.032
nucleoside phosphate biosynthetic processGO:19012931090.032
establishment of protein localization to organelleGO:00725941720.032
positive regulation of map kinase activityGO:0043406800.032
regulation of angiogenesisGO:0045765920.031
hindbrain developmentGO:003090230.031
organonitrogen compound biosynthetic processGO:19015662000.031
cation transportGO:00068123310.031
regulation of rho protein signal transductionGO:0035023790.030
tube morphogenesisGO:0035239950.030
positive regulation of transportGO:00510503360.030
response to growth factorGO:00708482050.030
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.029
regulation of map kinase activityGO:00434051080.029
ossificationGO:00015031210.029
positive regulation of organelle organizationGO:00106381950.029
defense responseGO:00069523150.029
regenerationGO:003109940.028
cellular response to growth factor stimulusGO:00713631970.028
dephosphorylationGO:00163112090.028
cell divisionGO:00513011680.028
response to abiotic stimulusGO:00096283360.028
positive regulation of protein serine threonine kinase activityGO:00719021190.028
regulation of response to external stimulusGO:00321012220.028
negative regulation of cellular protein metabolic processGO:00322693530.028
regulation of apoptotic signaling pathwayGO:20012331750.027
mitotic cell cycle phase transitionGO:00447721620.027
cell growthGO:00160491600.027
positive regulation of cell deathGO:00109422630.027
positive regulation of cell developmentGO:0010720920.027
cellular macromolecular complex assemblyGO:00346223240.027
protein localization to nucleusGO:00345041360.027
neuroblast proliferationGO:000740540.027
organ formationGO:004864530.026
epithelial tube branching involved in lung morphogenesisGO:006044140.026
regulation of secretionGO:00510461940.026
regulation of cell growthGO:00015581350.026
cell cycle phase transitionGO:00447701730.026
response to woundingGO:00096111680.026
regulation of cell projection organizationGO:00313441070.026
purine ribonucleotide biosynthetic processGO:0009152790.026
stress activated mapk cascadeGO:0051403930.026
regulation of establishment of protein localizationGO:00702012420.026
neuron developmentGO:00486661130.026
regulation of vasculature developmentGO:1901342970.026
transmembrane transportGO:00550853990.026
innate immune responseGO:00450871780.026
anterior posterior axis specificationGO:000994820.026
organ morphogenesisGO:00098871470.026
organic hydroxy compound metabolic processGO:19016151470.025
cellular response to dna damage stimulusGO:00069743790.025
inorganic ion transmembrane transportGO:00986602310.025
purine containing compound biosynthetic processGO:0072522880.025
nuclear importGO:00511701060.025
erk1 and erk2 cascadeGO:00703711040.025
neurogenesisGO:00220081690.025
cell projection morphogenesisGO:00488581290.025
morphogenesis of embryonic epitheliumGO:001633140.025
blastoderm segmentationGO:000735020.025
hematopoietic or lymphoid organ developmentGO:00485341860.025
positive regulation of rho gtpase activityGO:0032321560.025
digestive system developmentGO:0055123750.024
neurological system processGO:00508771630.024
positive regulation of camp biosynthetic processGO:0030819350.024
regulation of proteolysisGO:00301622930.024
regulation of intracellular transportGO:00323861950.024
immune system developmentGO:00025201950.024
regulation of stress activated protein kinase signaling cascadeGO:0070302850.024
regulation of stress activated mapk cascadeGO:0032872840.024
regulation of erk1 and erk2 cascadeGO:0070372990.024
nucleocytoplasmic transportGO:00069131760.024
regulation of rho gtpase activityGO:0032319660.024
negative regulation of apoptotic processGO:00430663160.024
ion homeostasisGO:00508012300.024
head developmentGO:00603221080.024
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.023
positive regulation of apoptotic processGO:00430652460.023
regulation of secretion by cellGO:19035301770.023
response to lipidGO:00339932060.023
response to external biotic stimulusGO:00432072610.023
stem cell divisionGO:001714520.023
negative regulation of protein modification processGO:00314002000.023
single organism cell adhesionGO:00986021790.023
protein catabolic processGO:00301633250.023
forebrain generation of neuronsGO:002187230.023
nucleotide biosynthetic processGO:00091651090.023
regulation of sequence specific dna binding transcription factor activityGO:00510902110.023
response to biotic stimulusGO:00096072760.022
response to nitrogen compoundGO:19016981840.022
protein import into nucleusGO:00066061040.022
positive regulation of cell motilityGO:20001471770.022
hemopoiesisGO:00300971800.022
regulation of nervous system developmentGO:0051960880.022
cell part morphogenesisGO:00329901370.022
ameboidal type cell migrationGO:00016671350.022
memoryGO:000761330.022
regulation of dna metabolic processGO:00510521530.022
single organismal cell cell adhesionGO:00163371480.022
cellular protein complex assemblyGO:00436231880.022
negative regulation of locomotionGO:00400131180.022
oxidation reduction processGO:00551143960.022
negative regulation of cell differentiationGO:00455961710.022
metal ion transportGO:00300012720.021
lipid biosynthetic processGO:00086101770.021
cation homeostasisGO:00550801890.021
microtubule based processGO:00070172100.021
jnk cascadeGO:0007254800.021
cyclic purine nucleotide metabolic processGO:0052652600.021
calcium ion transportGO:00068161470.021
membrane organizationGO:00610242920.021
lung alveolus developmentGO:004828640.021
ion transmembrane transportGO:00342203380.021
glial cell migrationGO:000834740.021
response to organonitrogen compoundGO:00102431560.021
cellular macromolecule catabolic processGO:00442653800.021
anion transportGO:00068201610.021
positive regulation of immune system processGO:00026842830.021
protein importGO:00170381300.021
spermatid differentiationGO:004851540.021
regulation of camp biosynthetic processGO:0030817450.021
cellular homeostasisGO:00197251960.020
regulation of cell morphogenesisGO:00226041530.020
positive regulation of erk1 and erk2 cascadeGO:0070374750.020
ribose phosphate biosynthetic processGO:0046390820.020
dna replicationGO:00062601160.020
cellular response to nitrogen compoundGO:19016991440.020
single organism nuclear importGO:19025931040.020
single organism membrane organizationGO:00448022680.020
purine nucleotide biosynthetic processGO:0006164840.020
specification of organ identityGO:001009230.020
carbohydrate metabolic processGO:00059752070.020
negative regulation of rho gtpase activityGO:003425940.020
positive regulation of proteolysisGO:00458621420.020
nuclear transportGO:00511691790.020
maintenance of locationGO:00512351120.020
digestive tract developmentGO:0048565750.020
ribonucleotide biosynthetic processGO:0009260810.020
regulation of axon guidanceGO:190266730.020
protein targetingGO:00066051870.020
regulation of cell cycle phase transitionGO:19019871260.020
cell cycle arrestGO:0007050710.020
protein maturationGO:00516042330.020
tissue migrationGO:00901301190.020
epithelial cell differentiationGO:00308551410.019
positive regulation of stress activated protein kinase signaling cascadeGO:0070304610.019
camp metabolic processGO:0046058610.019
central nervous system developmentGO:00074171230.019
negative regulation of cellular amino acid metabolic processGO:004576320.019
positive regulation of cytoskeleton organizationGO:0051495830.019
tissue morphogenesisGO:0048729960.019
negative regulation of cellular amine metabolic processGO:003323930.019
regulation of anatomical structure sizeGO:00900661010.019
protein targeting to nucleusGO:00447441040.019
negative regulation of cell cycle processGO:00109481210.019
negative regulation of cell migrationGO:00303361020.019
regulation of vesicle mediated transportGO:00606271300.019
positive regulation of programmed cell deathGO:00430682490.019
protein processingGO:00164852260.019
adult locomotory behaviorGO:000834410.018
somatic stem cell divisionGO:004810310.018
response to other organismGO:00517072610.018
positive regulation of protein kinase activityGO:00458601900.018
regulation of cyclic nucleotide metabolic processGO:0030799630.018
secretion by cellGO:00329402260.018
actin mediated cell contractionGO:0070252120.018
epithelial cell proliferation involved in lung morphogenesisGO:006050230.018
metal ion homeostasisGO:00550651690.018
motor neuron axon guidanceGO:000804520.018
response to organic cyclic compoundGO:00140702040.018
neuron projection developmentGO:00311751060.018
brain developmentGO:0007420970.018
negative regulation of transportGO:00510511760.018
response to hormoneGO:00097251750.018
purine ribonucleoside monophosphate metabolic processGO:00091671860.018
cyclic nucleotide biosynthetic processGO:0009190610.018
divalent inorganic cation transportGO:00725111580.018
regulation of multi organism processGO:00439001570.018
regulation of mitotic cell cycleGO:00073461890.018
regulation of purine nucleotide biosynthetic processGO:1900371500.018
spermatid developmentGO:000728640.018
regulation of epithelial cell migrationGO:0010632930.018
positive regulation of synaptic transmissionGO:005080640.018
regulation of peptidase activityGO:00525471800.018
embryonic epithelial tube formationGO:000183840.017
nucleoside monophosphate metabolic processGO:00091231910.017
axis elongationGO:000340140.017
tripartite regional subdivisionGO:000735120.017
positive regulation of stress activated mapk cascadeGO:0032874600.017
behaviorGO:00076101120.017
negative regulation of intracellular signal transductionGO:19025321830.017
regulation of wnt signaling pathwayGO:00301111230.017
inorganic cation transmembrane transportGO:00986621940.017
anterior posterior axis specification embryoGO:000859520.017
startle responseGO:000196430.017
gastrulationGO:0007369510.017
response to cytokineGO:00340972320.017
negative regulation of apoptotic signaling pathwayGO:2001234970.017
peptidyl tyrosine phosphorylationGO:00181081700.017
regulation of jnk cascadeGO:0046328730.017
alcohol metabolic processGO:00060661140.017
small molecule biosynthetic processGO:00442831570.017
regulation of protein transportGO:00512232130.017
negative regulation of cell motilityGO:20001461040.017
response to axon injuryGO:004867810.017
inner ear morphogenesisGO:004247240.017
morphogenesis of a polarized epitheliumGO:000173830.017
wound healingGO:00420601150.017
stem cell differentiationGO:0048863930.017
protein kinase b signalingGO:0043491690.017
cell substrate adhesionGO:00315891320.017
cellular protein catabolic processGO:00442572610.017
regulation of mitotic cell cycle phase transitionGO:19019901180.017
cellular chemical homeostasisGO:00550821800.017
muscle tissue developmentGO:0060537620.017
regulation of cellular component sizeGO:0032535820.017
actin filament based movementGO:0030048170.017
negative regulation of protein phosphorylationGO:00019331400.017
purine nucleoside monophosphate metabolic processGO:00091261860.017
monocarboxylic acid metabolic processGO:00327871850.017
sequestering of metal ionGO:0051238240.017
epithelium migrationGO:00901321190.017
regulation of muscle organ developmentGO:0048634270.017
digestive tract morphogenesisGO:0048546560.016
wnt signaling pathwayGO:00160551560.016
cellular cation homeostasisGO:00300031630.016
positive regulation of jnk cascadeGO:0046330520.016
calcium ion homeostasisGO:00550741220.016
negative regulation of mitotic cell cycleGO:00459301020.016
negative regulation of catabolic processGO:00098951040.016
positive regulation of dna metabolic processGO:0051054730.016
cytokine productionGO:00018162470.016
cation transmembrane transportGO:00986552380.016
limbic system developmentGO:002176130.016
embryonic morphogenesisGO:0048598850.016
atp metabolic processGO:00460341760.016
rhythmic behaviorGO:000762220.016
chromatin modificationGO:00165682980.016
somatic muscle developmentGO:000752510.016
regulation of intracellular protein transportGO:00331571230.016
regulation of cytoplasmic transportGO:19036491490.016
single organism carbohydrate metabolic processGO:00447231930.016
positive regulation of cell cycleGO:00457871400.016
epithelial cell migrationGO:00106311190.016
positive regulation of purine nucleotide biosynthetic processGO:1900373380.016
neuronal stem cell divisionGO:003644510.016
reproductive processGO:00224141060.016
matingGO:000761810.016
cellular ion homeostasisGO:00068731680.016
thymus developmentGO:004853830.016
negative regulation of phosphorylationGO:00423261740.016
sequestering of calcium ionGO:0051208170.016
regulation of axon extension involved in axon guidanceGO:004884120.016
cellular response to external stimulusGO:00714961110.015
chromatin organizationGO:00063253510.015
proteolysis involved in cellular protein catabolic processGO:00516032440.015
positive regulation of rac gtpase activityGO:0032855310.015
sex determinationGO:000753030.015
negative regulation of cell cycle phase transitionGO:1901988890.015
regulation of endopeptidase activityGO:00525481700.015
regulation of immune responseGO:00507762010.015
positive regulation of cellular component biogenesisGO:00440891580.015
endomembrane system organizationGO:00102561960.015
reactive oxygen species metabolic processGO:0072593750.015
sensory perception of smellGO:000760820.015
salivary gland morphogenesisGO:000743540.015
ubiquitin dependent protein catabolic processGO:00065112060.015
neurotransmitter secretionGO:000726940.015
endothelial cell migrationGO:0043542860.015
cellular response to organonitrogen compoundGO:00714171240.015
regulation of cytokine productionGO:00018172320.015
single organism reproductive processGO:0044702980.015
cellular response to organic cyclic compoundGO:00714071270.015
ribonucleoside monophosphate metabolic processGO:00091611870.015
divalent metal ion transportGO:00708381520.015
organelle assemblyGO:00709251760.015
nerve developmentGO:002167540.015
regulation of protein complex assemblyGO:00432541470.015
regulation of neurogenesisGO:0050767820.015
regulation of meiotic cell cycleGO:005144540.015
histone modificationGO:00165702510.015
cellular metal ion homeostasisGO:00068751460.015
replicative cell agingGO:000130230.015
negative regulation of striated muscle tissue developmentGO:0045843110.015
circadian behaviorGO:004851220.015
associative learningGO:000830610.015
modification dependent protein catabolic processGO:00199412090.015
blood circulationGO:00080151130.015
urogenital system developmentGO:0001655650.015
striated muscle tissue developmentGO:0014706590.015
post embryonic organ developmentGO:004856910.015
kidney developmentGO:0001822530.015
interspecies interaction between organismsGO:00444191560.014
atp catabolic processGO:00062001570.014
camp biosynthetic processGO:0006171470.014
cell cycle checkpointGO:00000751170.014
protein ubiquitinationGO:00165673140.014
nitrogen compound transportGO:00717051910.014
peptidyl tyrosine modificationGO:00182121700.014
proteasomal protein catabolic processGO:00104981760.014
autophagyGO:0006914880.014
positive regulation of epithelial cell proliferationGO:0050679650.014
cell type specific apoptotic processGO:00972851250.014

PLCE1 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:145661740.043
cancerDOID:1621670.043
musculoskeletal system diseaseDOID:172230.042
organ system cancerDOID:00506861640.042
cardiovascular system diseaseDOID:12871060.035
muscular diseaseDOID:00800001140.024
disease of metabolismDOID:00146672950.023
muscle tissue diseaseDOID:661130.023
nervous system diseaseDOID:8634310.022
sensory system diseaseDOID:00501552030.022
gastrointestinal system cancerDOID:3119520.022
myopathyDOID:4231040.021
eye and adnexa diseaseDOID:14921500.021
central nervous system diseaseDOID:3311860.018
inherited metabolic disorderDOID:6552420.018
heart diseaseDOID:114680.018
eye diseaseDOID:56141490.017
connective tissue diseaseDOID:651090.016
bone diseaseDOID:0080001880.015
retinal diseaseDOID:56791180.015