Homo sapiens

0 known processes

PLEKHN1

pleckstrin homology domain containing, family N member 1

(Aliases: MGC120616,DKFZp434H2010,RP11-54O7.7,MGC120613)

PLEKHN1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular ketone metabolic processGO:0042180800.057
cellular amino acid metabolic processGO:00065201160.055
post embryonic developmentGO:000979120.054
positive regulation of phosphorylationGO:00423273940.047
lipid metabolic processGO:00066293810.047
multicellular organismal agingGO:001025930.044
regulation of cellular amino acid metabolic processGO:000652160.042
determination of adult lifespanGO:000834020.041
ras protein signal transductionGO:0007265730.040
nucleoside phosphate catabolic processGO:19012924120.039
regulation of cell cycleGO:00517263930.038
positive regulation of catabolic processGO:00098963100.037
signal transduction by phosphorylationGO:00230142970.036
regulation of cellular ketone metabolic processGO:0010565500.036
cytoplasmic transportGO:00164823790.036
organophosphate catabolic processGO:00464344300.035
regulation of cellular amine metabolic processGO:0033238110.035
purine ribonucleoside catabolic processGO:00461303980.035
cellular amine metabolic processGO:0044106410.035
purine ribonucleoside metabolic processGO:00461284370.035
ribonucleotide catabolic processGO:00092614050.035
nucleoside triphosphate metabolic processGO:00091414220.035
nucleoside triphosphate catabolic processGO:00091433940.035
ribonucleoside triphosphate metabolic processGO:00091994120.034
regulation of cellular component movementGO:00512703340.034
nucleotide catabolic processGO:00091664080.033
cellular lipid metabolic processGO:00442553030.033
nucleoside catabolic processGO:00091644080.033
immune responseGO:00069553070.033
glycosyl compound catabolic processGO:19016584130.033
cellular macromolecule catabolic processGO:00442653800.033
purine ribonucleoside triphosphate catabolic processGO:00092073910.033
purine containing compound catabolic processGO:00725234110.033
ribonucleoside triphosphate catabolic processGO:00092033910.032
purine nucleoside triphosphate metabolic processGO:00091444120.032
locomotory behaviorGO:000762610.032
regulation of locomotionGO:00400123290.032
small gtpase mediated signal transductionGO:0007264780.032
positive regulation of hydrolase activityGO:00513453310.032
purine nucleoside catabolic processGO:00061523980.032
positive regulation of cellular amine metabolic processGO:003324070.032
purine ribonucleoside triphosphate metabolic processGO:00092054110.032
positive regulation of transportGO:00510503360.032
positive regulation of cellular amino acid metabolic processGO:004576430.031
cytokine productionGO:00018162470.031
purine nucleoside triphosphate catabolic processGO:00091463920.031
female gamete generationGO:000729220.031
innate immune responseGO:00450871780.031
membrane organizationGO:00610242920.031
segmentationGO:003528240.030
positive regulation of immune system processGO:00026842830.030
positive regulation of cell proliferationGO:00082843010.030
purine nucleotide catabolic processGO:00061954050.030
defense responseGO:00069523150.030
single organism membrane organizationGO:00448022680.030
ribonucleoside catabolic processGO:00424544060.030
amine metabolic processGO:0009308440.029
actin filament based processGO:00300292240.029
negative regulation of protein metabolic processGO:00512483910.029
regulation of anatomical structure morphogenesisGO:00226032860.029
single organism cellular localizationGO:19025803320.029
regulation of transferase activityGO:00513383550.029
positive regulation of protein phosphorylationGO:00019343130.028
negative regulation of cellular protein metabolic processGO:00322693530.028
oogenesisGO:004847720.027
cellular response to dna damage stimulusGO:00069743790.027
regulation of cytokine productionGO:00018172320.027
guanosine containing compound catabolic processGO:19010692390.027
regulation of cell motilityGO:20001452990.027
regulation of mapk cascadeGO:00434082620.027
protein catabolic processGO:00301633250.027
purine ribonucleotide catabolic processGO:00091544040.026
epidermis morphogenesisGO:004873030.025
enzyme linked receptor protein signaling pathwayGO:00071673030.025
guanosine containing compound metabolic processGO:19010682440.025
negative regulation of cell deathGO:00605483450.025
negative regulation of apoptotic processGO:00430663160.025
cellular protein catabolic processGO:00442572610.025
epithelium developmentGO:00604292270.025
negative regulation of multicellular organismal processGO:00512413170.025
secretionGO:00469032540.025
cell activationGO:00017752130.025
positive regulation of cellular catabolic processGO:00313312840.025
rho protein signal transductionGO:0007266260.025
regulation of cellular component biogenesisGO:00440872810.024
regulation of protein localizationGO:00328802960.024
protein localization to organelleGO:00333652800.024
intracellular protein transportGO:00068862700.024
positive regulation of cellular component organizationGO:00511303760.024
negative regulation of catalytic activityGO:00430863350.024
gtp catabolic processGO:00061842370.024
regulation of gtpase activityGO:00430871800.024
negative regulation of programmed cell deathGO:00430693210.024
regulation of cellular response to stressGO:00801352440.023
cellular component morphogenesisGO:00329893140.023
mapk cascadeGO:00001652880.023
protein maturationGO:00516042330.023
hindbrain developmentGO:003090230.023
regulation of proteolysisGO:00301622930.023
gtp metabolic processGO:00460392390.023
regulation of cell migrationGO:00303342890.023
proteolysis involved in cellular protein catabolic processGO:00516032440.022
positive regulation of developmental processGO:00510943140.022
regulation of cell differentiationGO:00455953930.022
mitotic cell cycleGO:00002783260.022
biological adhesionGO:00226103310.022
regulation of kinase activityGO:00435493140.022
vesicle mediated transportGO:00161923710.022
regulation of protein kinase activityGO:00458592890.022
memoryGO:000761330.021
nervous system developmentGO:00073992930.021
cell morphogenesisGO:00009022960.021
regulation of nucleoside metabolic processGO:00091182090.021
regulation of nucleotide metabolic processGO:00061402690.021
cell developmentGO:00484683280.021
oxidation reduction processGO:00551143960.021
neuromuscular junction developmentGO:000752830.021
regulation of cell cycle processGO:00105642660.021
negative regulation of cellular component organizationGO:00511292350.021
small molecule biosynthetic processGO:00442831570.020
maintenance of locationGO:00512351120.020
cell adhesionGO:00071553250.020
regulation of protein transportGO:00512232130.020
response to external biotic stimulusGO:00432072610.020
regulation of cytoskeleton organizationGO:00514931770.020
positive regulation of mapk cascadeGO:00434101900.020
positive regulation of transferase activityGO:00513472270.020
regenerationGO:003109940.020
dephosphorylationGO:00163112090.020
regulation of intracellular transportGO:00323861950.020
anterior posterior axis specificationGO:000994820.020
protein processingGO:00164852260.020
regulation of purine nucleotide catabolic processGO:00331212050.019
negative regulation of phosphate metabolic processGO:00459362670.019
regulation of response to external stimulusGO:00321012220.019
regulation of establishment of protein localizationGO:00702012420.019
ubiquitin dependent protein catabolic processGO:00065112060.019
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.019
modification dependent macromolecule catabolic processGO:00436322120.019
regulation of nucleotide catabolic processGO:00308112050.019
regulation of gtp catabolic processGO:00331241800.019
cellular response to endogenous stimulusGO:00714953360.019
protein targetingGO:00066051870.019
regulation of purine nucleotide metabolic processGO:19005422640.019
positive regulation of kinase activityGO:00336742040.019
regulation of reactive oxygen species metabolic processGO:2000377410.019
positive regulation of apoptotic processGO:00430652460.019
positive regulation of cellular component movementGO:00512721810.019
negative regulation of phosphorus metabolic processGO:00105632670.019
negative regulation of developmental processGO:00510932470.018
response to oxygen containing compoundGO:19017003690.018
positive regulation of organelle organizationGO:00106381950.018
endomembrane system organizationGO:00102561960.018
cell projection organizationGO:00300302520.018
regulation of reactive oxygen species biosynthetic processGO:190342630.018
system processGO:00030083490.018
actin cytoskeleton organizationGO:00300362070.018
positive regulation of cell motilityGO:20001471770.018
lipid biosynthetic processGO:00086101770.018
apoptotic signaling pathwayGO:00971902680.018
anatomical structure formation involved in morphogenesisGO:00486462840.018
response to abiotic stimulusGO:00096283360.018
g protein coupled receptor signaling pathwayGO:00071862070.018
calcium ion homeostasisGO:00550741220.018
reactive oxygen species metabolic processGO:0072593750.018
positive regulation of nucleoside metabolic processGO:00459791860.017
positive regulation of purine nucleotide catabolic processGO:00331231850.017
spermatid differentiationGO:004851540.017
cellular response to oxygen containing compoundGO:19017012760.017
mitotic cell cycle processGO:19030472860.017
positive regulation of nucleotide catabolic processGO:00308131850.017
modification dependent protein catabolic processGO:00199412090.017
response to growth factorGO:00708482050.017
morphogenesis of embryonic epitheliumGO:001633140.017
positive regulation of purine nucleotide metabolic processGO:19005442270.017
blastoderm segmentationGO:000735020.017
monocarboxylic acid metabolic processGO:00327871850.017
protein ubiquitinationGO:00165673140.017
epithelial cell differentiationGO:00308551410.017
peripheral nervous system developmentGO:000742220.016
positive regulation of cell migrationGO:00303351720.016
cellular macromolecular complex assemblyGO:00346223240.016
secretion by cellGO:00329402260.016
response to woundingGO:00096111680.016
negative regulation of cellular amino acid metabolic processGO:004576320.016
regulation of i kappab kinase nf kappab signalingGO:00431221620.016
cellular response to cytokine stimulusGO:00713451810.016
positive regulation of programmed cell deathGO:00430682490.016
central nervous system developmentGO:00074171230.016
embryonic epithelial tube formationGO:000183840.016
protein modification by small protein conjugationGO:00324463420.016
spermatid developmentGO:000728640.016
metal ion transportGO:00300012720.016
cellular cation homeostasisGO:00300031630.016
regulation of sequence specific dna binding transcription factor activityGO:00510902110.016
positive regulation of nucleotide metabolic processGO:00459812300.016
circadian behaviorGO:004851220.016
protein localization to membraneGO:00726571600.016
regulation of immune responseGO:00507762010.016
transmembrane transportGO:00550853990.016
establishment of protein localization to organelleGO:00725941720.016
regulation of ras protein signal transductionGO:00465781550.016
sequestering of metal ionGO:0051238240.015
hair follicle morphogenesisGO:003106920.015
positive regulation of gtp catabolic processGO:00331261660.015
negative regulation of protein modification processGO:00314002000.015
cation transportGO:00068123310.015
anterior posterior axis specification embryoGO:000859520.015
chromatin organizationGO:00063253510.015
negative regulation of cell differentiationGO:00455961710.015
positive regulation of cytokine productionGO:00018191670.015
regulation of protein catabolic processGO:00421761550.015
rhythmic behaviorGO:000762220.015
positive regulation of protein kinase activityGO:00458601900.015
single organism cell adhesionGO:00986021790.015
cellular homeostasisGO:00197251960.015
response to biotic stimulusGO:00096072760.015
wnt signaling pathwayGO:00160551560.015
metencephalon developmentGO:002203720.015
regulation of protein processingGO:00706131500.015
response to other organismGO:00517072610.015
sequestering of calcium ionGO:0051208170.015
posttranscriptional regulation of gene expressionGO:00106082130.015
response to cytokineGO:00340972320.015
positive regulation of cell differentiationGO:00455972110.015
proteasomal protein catabolic processGO:00104981760.015
regulation of protein complex assemblyGO:00432541470.014
oocyte developmentGO:004859910.014
reactive nitrogen species metabolic processGO:200105730.014
associative learningGO:000830610.014
chemical homeostasisGO:00488783060.014
regulation of cytoplasmic transportGO:19036491490.014
positive regulation of reactive oxygen species biosynthetic processGO:190342820.014
immune system developmentGO:00025201950.014
histone modificationGO:00165702510.014
oocyte differentiationGO:000999420.014
hemopoiesisGO:00300971800.014
head developmentGO:00603221080.014
leukocyte activationGO:00453211640.014
cellular response to growth factor stimulusGO:00713631970.014
negative regulation of cellular amine metabolic processGO:003323930.014
immune effector processGO:00022521590.014
regulation of cell adhesionGO:00301551660.014
nuclear transportGO:00511691790.014
regulation of ion transportGO:00432691890.014
visual behaviorGO:000763220.014
negative regulation of intracellular signal transductionGO:19025321830.014
microtubule based processGO:00070172100.014
positive regulation of cell deathGO:00109422630.014
cell substrate adhesionGO:00315891320.014
hematopoietic or lymphoid organ developmentGO:00485341860.014
oxidative stress induced premature senescenceGO:009040330.014
response to virusGO:00096151260.014
glycerolipid metabolic processGO:00464861070.014
tripartite regional subdivisionGO:000735120.014
chromatin modificationGO:00165682980.014
positive regulation of gtpase activityGO:00435471660.014
motor neuron axon guidanceGO:000804520.014
activation of immune responseGO:00022531140.014
regulation of wnt signaling pathwayGO:00301111230.014
cell cell signalingGO:00072671550.014
negative regulation of protein processingGO:00109551420.014
regulation of peptidase activityGO:00525471800.014
positive regulation of i kappab kinase nf kappab signalingGO:00431231320.014
response to fungusGO:000962040.013
dna repairGO:00062811980.013
positive regulation of cellular component biogenesisGO:00440891580.013
regulation of stress activated protein kinase signaling cascadeGO:0070302850.013
carbohydrate metabolic processGO:00059752070.013
positive regulation of ras gtpase activityGO:00323201170.013
organelle assemblyGO:00709251760.013
regulation of jnk cascadeGO:0046328730.013
regulation of ras gtpase activityGO:00323181280.013
endosomal transportGO:00161971290.013
actin filament organizationGO:00070151280.013
regulation of protein maturationGO:19033171500.013
micturitionGO:006007330.013
positive regulation of reactive oxygen species metabolic processGO:2000379240.013
photoreceptor cell differentiationGO:004653020.013
establishment of protein localization to membraneGO:00901501210.013
positive regulation of locomotionGO:00400171860.013
syncytium formation by plasma membrane fusionGO:000076820.013
cellular ion homeostasisGO:00068731680.013
embryonic forelimb morphogenesisGO:003511540.013
matingGO:000761810.013
nitrogen compound transportGO:00717051910.013
regulation of secretionGO:00510461940.013
negative regulation of hydrolase activityGO:00513461820.013
cellular protein complex assemblyGO:00436231880.013
jnk cascadeGO:0007254800.013
nucleocytoplasmic transportGO:00069131760.013
regulation of actin cytoskeleton organizationGO:00329561160.013
regulation of apoptotic signaling pathwayGO:20012331750.013
negative regulation of protein maturationGO:19033181420.013
adult locomotory behaviorGO:000834410.013
regulation of mitotic cell cycleGO:00073461890.013
viral life cycleGO:00190581320.013
i kappab kinase nf kappab signalingGO:00072491660.013
stress activated mapk cascadeGO:0051403930.013
neurological system processGO:00508771630.013
rna processingGO:00063962550.013
neuron differentiationGO:00301821380.013
leukocyte migrationGO:00509001070.012
regulation of viral processGO:00507921030.012
positive regulation of immune responseGO:00507781590.012
positive regulation of sequence specific dna binding transcription factor activityGO:00510911310.012
organic hydroxy compound metabolic processGO:19016151470.012
compound eye developmentGO:004874910.012
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.012
ameboidal type cell migrationGO:00016671350.012
peptidyl tyrosine modificationGO:00182121700.012
regulation of multi organism processGO:00439001570.012
peptidyl tyrosine phosphorylationGO:00181081700.012
cardiovascular system developmentGO:00723582620.012
wound healingGO:00420601150.012
organ morphogenesisGO:00098871470.012
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.012
regulation of neural precursor cell proliferationGO:200017740.012
cell divisionGO:00513011680.012
morphogenesis of a polarized epitheliumGO:000173830.012
mitotic cell cycle phase transitionGO:00447721620.012
reactive oxygen species biosynthetic processGO:190340940.012
cell cycle phase transitionGO:00447701730.012
protein localization to nucleusGO:00345041360.012
negative regulation of cell proliferationGO:00082852280.012
regulation of endopeptidase activityGO:00525481700.012
ion transmembrane transportGO:00342203380.012
regulation of small gtpase mediated signal transductionGO:00510561560.012
protein oligomerizationGO:00512591730.012
regulation of intracellular protein transportGO:00331571230.012
regulation of protein serine threonine kinase activityGO:00719001790.012
regulation of vesicle mediated transportGO:00606271300.012
opioid receptor signaling pathwayGO:003800340.012
lipid catabolic processGO:0016042840.012
actin mediated cell contractionGO:0070252120.012
single organism carbohydrate metabolic processGO:00447231930.012
canonical wnt signaling pathwayGO:00600701160.012
negative regulation of proteolysisGO:00458611320.012
negative regulation of gliogenesisGO:001401430.012
vasculature developmentGO:00019441810.012
multi organism cellular processGO:00447641560.012
negative regulation of phosphorylationGO:00423261740.012
cerebellum developmentGO:002154920.012
tube closureGO:006060630.012
regulation of defense responseGO:00313471540.012
fatty acid metabolic processGO:00066311150.012
ion homeostasisGO:00508012300.012
stress activated protein kinase signaling cascadeGO:0031098940.012
regulation of stress activated mapk cascadeGO:0032872840.012
phospholipid metabolic processGO:0006644990.012
plasma membrane organizationGO:00070091150.012
glycoprotein metabolic processGO:00091001100.012
divalent metal ion transportGO:00708381520.012
taxisGO:00423301570.012
single organismal cell cell adhesionGO:00163371480.012
negative regulation of transferase activityGO:00513481240.012
covalent chromatin modificationGO:00165692540.012
regulation of actin filament based processGO:00329701410.011
response to axon injuryGO:004867810.011
regulation of cell morphogenesisGO:00226041530.011
positive regulation of intracellular transportGO:00323881040.011
regulation of cell projection organizationGO:00313441070.011
cellular response to lipidGO:00713961270.011
primary neural tube formationGO:001402030.011
cation homeostasisGO:00550801890.011
response to oxygen levelsGO:00704821000.011
negative regulation of organelle organizationGO:00106391260.011
ribonucleoside monophosphate metabolic processGO:00091611870.011
cell projection assemblyGO:00300311260.011
purine ribonucleoside monophosphate metabolic processGO:00091671860.011
negative regulation of cell cycleGO:00457861930.011
cellular lipid catabolic processGO:0044242650.011
somitogenesisGO:000175620.011
regulation of symbiosis encompassing mutualism through parasitismGO:00439031090.011
tissue regenerationGO:004224630.011
cellular metal ion homeostasisGO:00068751460.011
endocytosisGO:00068971590.011
interspecies interaction between organismsGO:00444191560.011
regulation of cell activationGO:00508651250.011
defense response to other organismGO:00985421290.011
negative regulation of cell migrationGO:00303361020.011
growthGO:00400072020.011
negative regulation of protein phosphorylationGO:00019331400.011
positive regulation of cell cycleGO:00457871400.011
regulation of vasculature developmentGO:1901342970.011
response to lipidGO:00339932060.011
inner ear morphogenesisGO:004247240.011
negative regulation of transportGO:00510511760.011
organophosphate biosynthetic processGO:00904071630.011
organ formationGO:004864530.011
forelimb morphogenesisGO:003513640.011
positive regulation of protein transportGO:00512221350.011
ventral spinal cord developmentGO:002151710.011
microtubule cytoskeleton organizationGO:00002261760.011
positive regulation of secretionGO:00510471160.011
response to organic cyclic compoundGO:00140702040.011
viral processGO:00160321460.011
cellular chemical homeostasisGO:00550821800.011
calcium ion transportGO:00068161470.011
regulation of cell developmentGO:00602841610.011
epidermis developmentGO:0008544590.011
negative regulation of locomotionGO:00400131180.011
regulation of secretion by cellGO:19035301770.011
divalent inorganic cation transportGO:00725111580.011
cellular response to external stimulusGO:00714961110.011
positive regulation of stress activated protein kinase signaling cascadeGO:0070304610.011
cell part morphogenesisGO:00329901370.010
response to decreased oxygen levelsGO:0036293960.010
blood vessel developmentGO:00015681720.010
cellular organohalogen metabolic processGO:009034520.010
purine nucleoside monophosphate metabolic processGO:00091261860.010
glycerophospholipid metabolic processGO:0006650840.010
lymphocyte activationGO:00466491330.010
alcohol metabolic processGO:00060661140.010
blood coagulationGO:0007596760.010
behavioral response to ethanolGO:004814920.010
regulation of body fluid levelsGO:0050878990.010
regulation of cell cycle phase transitionGO:19019871260.010
cellular component disassemblyGO:0022411920.010
epithelial cell proliferationGO:00506731280.010
regulation of glial cell differentiationGO:004568530.010
neural tube formationGO:000184130.010
tissue morphogenesisGO:0048729960.010
carbohydrate derivative biosynthetic processGO:19011372070.010
melanin metabolic processGO:000658210.010
thymus developmentGO:004853830.010
regulation of epithelial cell proliferationGO:00506781130.010
protein modification by small protein removalGO:0070646920.010
tissue migrationGO:00901301190.010
regulation of canonical wnt signaling pathwayGO:0060828880.010
protein importGO:00170381300.010
negative regulation of catabolic processGO:00098951040.010

PLEKHN1 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
musculoskeletal system diseaseDOID:172230.026
disease of metabolismDOID:00146672950.019
central nervous system diseaseDOID:3311860.015
nervous system diseaseDOID:8634310.015
sensory system diseaseDOID:00501552030.014
eye and adnexa diseaseDOID:14921500.014
eye diseaseDOID:56141490.014
inherited metabolic disorderDOID:6552420.014
neurodegenerative diseaseDOID:12891020.013
disease of cellular proliferationDOID:145661740.012
immune system diseaseDOID:29141550.012
muscle tissue diseaseDOID:661130.012
muscular diseaseDOID:00800001140.012
connective tissue diseaseDOID:651090.012
cancerDOID:1621670.011
organ system cancerDOID:00506861640.011
retinal diseaseDOID:56791180.011
bone diseaseDOID:0080001880.010