Homo sapiens

0 known processes

PCSK1N

proprotein convertase subtilisin/kexin type 1 inhibitor

(Aliases: PROSAAS,SAAS)

PCSK1N biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
spinal cord developmentGO:002151040.071
post embryonic developmentGO:000979120.058
locomotory behaviorGO:000762610.058
cellular response to endogenous stimulusGO:00714953360.054
nervous system developmentGO:00073992930.053
ion transmembrane transportGO:00342203380.049
transmembrane transportGO:00550853990.048
segmentationGO:003528240.046
cellular amino acid metabolic processGO:00065201160.045
cell projection organizationGO:00300302520.044
regulation of cellular ketone metabolic processGO:0010565500.044
neuron fate commitmentGO:004866320.042
regulation of cell differentiationGO:00455953930.042
cation transportGO:00068123310.041
vesicle mediated transportGO:00161923710.039
regulation of cellular amino acid metabolic processGO:000652160.037
regulation of purine nucleotide metabolic processGO:19005422640.037
negative regulation of developmental processGO:00510932470.036
regulation of nucleotide metabolic processGO:00061402690.036
regulation of neurotransmitter secretionGO:004692830.035
cytoplasmic transportGO:00164823790.034
adult locomotory behaviorGO:000834410.034
system processGO:00030083490.034
peripheral nervous system developmentGO:000742220.034
cellular amine metabolic processGO:0044106410.034
regulation of locomotionGO:00400123290.033
cell differentiation in spinal cordGO:002151510.033
regulation of anatomical structure morphogenesisGO:00226032860.032
negative regulation of multicellular organismal processGO:00512413170.032
morphogenesis of embryonic epitheliumGO:001633140.032
regulation of cellular amine metabolic processGO:0033238110.032
amine metabolic processGO:0009308440.032
cell morphogenesisGO:00009022960.032
positive regulation of cell proliferationGO:00082843010.032
determination of adult lifespanGO:000834020.031
response to oxygen containing compoundGO:19017003690.031
multicellular organismal agingGO:001025930.031
mitotic cell cycleGO:00002783260.031
oogenesisGO:004847720.030
metal ion transportGO:00300012720.030
regulation of cell motilityGO:20001452990.029
negative regulation of protein metabolic processGO:00512483910.029
regulation of cell cycleGO:00517263930.029
cell developmentGO:00484683280.029
neurogenesisGO:00220081690.029
cellular response to dna damage stimulusGO:00069743790.029
regulation of cell developmentGO:00602841610.028
cation transmembrane transportGO:00986552380.028
ion homeostasisGO:00508012300.028
neuromuscular junction developmentGO:000752830.028
nucleoside triphosphate metabolic processGO:00091414220.027
positive regulation of cell deathGO:00109422630.027
neurotransmitter secretionGO:000726940.027
single organism membrane organizationGO:00448022680.027
response to abiotic stimulusGO:00096283360.027
female gamete generationGO:000729220.027
cellular lipid metabolic processGO:00442553030.027
actin filament based processGO:00300292240.027
regulation of protein localizationGO:00328802960.027
purine ribonucleoside triphosphate metabolic processGO:00092054110.026
regulation of cellular component movementGO:00512703340.026
dephosphorylationGO:00163112090.026
nitrogen compound transportGO:00717051910.026
negative regulation of cell differentiationGO:00455961710.026
purine ribonucleoside metabolic processGO:00461284370.026
nucleoside triphosphate catabolic processGO:00091433940.026
negative regulation of phosphate metabolic processGO:00459362670.026
ribonucleoside triphosphate metabolic processGO:00091994120.025
purine ribonucleoside triphosphate catabolic processGO:00092073910.025
cell cell signalingGO:00072671550.025
ribonucleoside triphosphate catabolic processGO:00092033910.025
small gtpase mediated signal transductionGO:0007264780.025
ras protein signal transductionGO:0007265730.025
cell adhesionGO:00071553250.025
inorganic ion transmembrane transportGO:00986602310.024
negative regulation of phosphorus metabolic processGO:00105632670.024
positive regulation of transportGO:00510503360.024
secretion by cellGO:00329402260.024
mitotic cell cycle processGO:19030472860.024
secretionGO:00469032540.024
embryonic epithelial tube formationGO:000183840.024
cellular ketone metabolic processGO:0042180800.024
positive regulation of apoptotic processGO:00430652460.024
negative regulation of catalytic activityGO:00430863350.023
positive regulation of phosphorylationGO:00423273940.023
negative regulation of cellular protein metabolic processGO:00322693530.023
organophosphate catabolic processGO:00464344300.023
cellular macromolecule catabolic processGO:00442653800.023
spinal cord dorsal ventral patterningGO:002151320.023
organonitrogen compound biosynthetic processGO:19015662000.023
regulation of protein kinase activityGO:00458592890.022
neuroblast proliferationGO:000740540.022
neurological system processGO:00508771630.022
brain developmentGO:0007420970.022
positive regulation of cellular catabolic processGO:00313312840.022
positive regulation of cellular amino acid metabolic processGO:004576430.022
positive regulation of neural precursor cell proliferationGO:200017920.022
regulation of kinase activityGO:00435493140.022
central nervous system developmentGO:00074171230.022
negative regulation of cellular component organizationGO:00511292350.022
cell fate commitment involved in pattern specificationGO:006058110.022
single organism cellular localizationGO:19025803320.022
regulation of neural precursor cell proliferationGO:200017740.022
regulation of cell migrationGO:00303342890.022
positive regulation of catabolic processGO:00098963100.022
lipid metabolic processGO:00066293810.021
inorganic cation transmembrane transportGO:00986621940.021
endomembrane system organizationGO:00102561960.021
signal transduction by phosphorylationGO:00230142970.021
regulation of transferase activityGO:00513383550.021
cellular response to growth factor stimulusGO:00713631970.021
cellular response to oxygen containing compoundGO:19017012760.021
anion transportGO:00068201610.021
negative regulation of cell migrationGO:00303361020.021
cellular component morphogenesisGO:00329893140.021
regulation of cellular response to stressGO:00801352440.021
ribonucleoside catabolic processGO:00424544060.021
neuron differentiationGO:00301821380.021
positive regulation of cellular amine metabolic processGO:003324070.021
regulation of mapk cascadeGO:00434082620.021
cellular macromolecular complex assemblyGO:00346223240.021
ventral spinal cord interneuron differentiationGO:002151410.021
purine nucleoside triphosphate metabolic processGO:00091444120.021
nucleoside phosphate catabolic processGO:19012924120.020
startle responseGO:000196430.020
negative regulation of gliogenesisGO:001401430.020
regulation of establishment of protein localizationGO:00702012420.020
positive regulation of kinase activityGO:00336742040.020
carbohydrate derivative biosynthetic processGO:19011372070.020
positive regulation of cellular component organizationGO:00511303760.020
purine containing compound catabolic processGO:00725234110.020
nucleotide catabolic processGO:00091664080.020
forebrain generation of neuronsGO:002187230.020
positive regulation of hydrolase activityGO:00513453310.020
regulation of cellular component biogenesisGO:00440872810.020
protein catabolic processGO:00301633250.020
intracellular protein transportGO:00068862700.020
positive regulation of purine nucleotide metabolic processGO:19005442270.019
somitogenesisGO:000175620.019
hindbrain developmentGO:003090230.019
protein localization to organelleGO:00333652800.019
membrane organizationGO:00610242920.019
regenerationGO:003109940.019
cell fate determinationGO:000170930.019
immune system developmentGO:00025201950.019
organophosphate biosynthetic processGO:00904071630.019
ribonucleotide catabolic processGO:00092614050.019
purine nucleoside catabolic processGO:00061523980.019
anterior posterior axis specificationGO:000994820.019
purine nucleotide catabolic processGO:00061954050.019
purine ribonucleoside catabolic processGO:00461303980.019
positive regulation of programmed cell deathGO:00430682490.019
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.019
regulation of cell cycle processGO:00105642660.019
memoryGO:000761330.019
blastoderm segmentationGO:000735020.019
negative regulation of programmed cell deathGO:00430693210.019
morphogenesis of a polarized epitheliumGO:000173830.019
positive regulation of protein phosphorylationGO:00019343130.019
negative regulation of apoptotic processGO:00430663160.018
regulation of ion transportGO:00432691890.018
sex determinationGO:000753030.018
guanosine containing compound metabolic processGO:19010682440.018
anatomical structure formation involved in morphogenesisGO:00486462840.018
negative regulation of cell proliferationGO:00082852280.018
cell cycle phase transitionGO:00447701730.018
negative regulation of cellular amine metabolic processGO:003323930.018
regulation of cell morphogenesisGO:00226041530.018
microtubule based processGO:00070172100.018
hematopoietic or lymphoid organ developmentGO:00485341860.018
negative regulation of cellular amino acid metabolic processGO:004576320.018
immune responseGO:00069553070.018
compound eye developmentGO:004874910.018
response to growth factorGO:00708482050.018
inner ear morphogenesisGO:004247240.018
rho protein signal transductionGO:0007266260.017
cartilage condensationGO:000150210.017
nuclear transportGO:00511691790.017
positive regulation of transferase activityGO:00513472270.017
cell part morphogenesisGO:00329901370.017
renal system pattern specificationGO:007204810.017
regulation of proteolysisGO:00301622930.017
mapk cascadeGO:00001652880.017
cytokine productionGO:00018162470.017
positive regulation of synaptic transmissionGO:005080640.017
purine nucleoside triphosphate catabolic processGO:00091463920.017
regulation of cytokine productionGO:00018172320.017
regulation of protein transportGO:00512232130.017
astrocyte differentiationGO:004870840.017
regulation of secretionGO:00510461940.017
glycosyl compound catabolic processGO:19016584130.017
proteasomal protein catabolic processGO:00104981760.017
negative regulation of cell deathGO:00605483450.017
generation of neuronsGO:00486991520.016
apoptotic signaling pathwayGO:00971902680.016
biological adhesionGO:00226103310.016
positive regulation of secretion by cellGO:19035321080.016
regulation of cyclic nucleotide metabolic processGO:0030799630.016
positive regulation of secretionGO:00510471160.016
nucleoside catabolic processGO:00091644080.016
regulation of neuronal synaptic plasticityGO:004816810.016
chemical homeostasisGO:00488783060.016
actin cytoskeleton organizationGO:00300362070.016
purine ribonucleotide catabolic processGO:00091544040.016
wnt signaling pathwayGO:00160551560.016
protein modification by small protein conjugationGO:00324463420.016
epithelium developmentGO:00604292270.016
regulation of cytoskeleton organizationGO:00514931770.016
cellular protein catabolic processGO:00442572610.016
positive regulation of protein kinase activityGO:00458601900.016
hemopoiesisGO:00300971800.016
head developmentGO:00603221080.016
protein localization to membraneGO:00726571600.016
nucleoside phosphate biosynthetic processGO:19012931090.016
ventral spinal cord developmentGO:002151710.016
purine containing compound biosynthetic processGO:0072522880.015
glial cell migrationGO:000834740.015
rhythmic behaviorGO:000762220.015
regulation of synaptic transmission dopaminergicGO:003222540.015
negative regulation of cell cycleGO:00457861930.015
guanosine containing compound catabolic processGO:19010692390.015
protein ubiquitinationGO:00165673140.015
proteolysis involved in cellular protein catabolic processGO:00516032440.015
t cell differentiation in thymusGO:003307740.015
circulatory system developmentGO:00723592620.015
nucleotide biosynthetic processGO:00091651090.015
regulation of mitotic cell cycleGO:00073461890.015
neuron projection developmentGO:00311751060.015
cell growthGO:00160491600.015
protein maturationGO:00516042330.015
negative regulation of protein modification processGO:00314002000.015
positive regulation of nucleotide catabolic processGO:00308131850.015
taxisGO:00423301570.015
positive regulation of cell differentiationGO:00455972110.015
negative regulation of cell motilityGO:20001461040.015
actin filament organizationGO:00070151280.015
mitochondrion organizationGO:00070051560.015
synaptic vesicle endocytosisGO:004848820.015
posttranscriptional regulation of gene expressionGO:00106082130.015
negative regulation of phosphorylationGO:00423261740.015
innate immune responseGO:00450871780.015
regulation of nucleoside metabolic processGO:00091182090.014
anterior posterior axis specification embryoGO:000859520.014
mitotic cell cycle phase transitionGO:00447721620.014
positive regulation of developmental processGO:00510943140.014
enzyme linked receptor protein signaling pathwayGO:00071673030.014
negative regulation of hydrolase activityGO:00513461820.014
protein targetingGO:00066051870.014
positive regulation of nucleotide metabolic processGO:00459812300.014
regulation of intracellular transportGO:00323861950.014
spermatid differentiationGO:004851540.014
regulation of neurogenesisGO:0050767820.014
oocyte developmentGO:004859910.014
regulation of apoptotic signaling pathwayGO:20012331750.014
positive regulation of gliogenesisGO:001401540.014
photoreceptor cell differentiationGO:004653020.014
negative regulation of blood pressureGO:004577630.014
monovalent inorganic cation transportGO:00156721280.014
negative regulation of axonogenesisGO:005077140.014
metencephalon developmentGO:002203720.014
regulation of purine nucleotide catabolic processGO:00331212050.014
carbohydrate metabolic processGO:00059752070.014
neural tube formationGO:000184130.014
regulation of cell growthGO:00015581350.014
forebrain regionalizationGO:002187130.014
organ formationGO:004864530.014
cell projection assemblyGO:00300311260.014
oocyte differentiationGO:000999420.014
forebrain neuron differentiationGO:002187930.014
regulation of cell projection organizationGO:00313441070.014
cation homeostasisGO:00550801890.014
motor neuron axon guidanceGO:000804520.014
divalent metal ion transportGO:00708381520.014
forelimb morphogenesisGO:003513640.014
cyclic purine nucleotide metabolic processGO:0052652600.014
single organism carbohydrate metabolic processGO:00447231930.013
regulation of secretion by cellGO:19035301770.013
nucleocytoplasmic transportGO:00069131760.013
positive regulation of nucleoside metabolic processGO:00459791860.013
regulation of growthGO:00400081650.013
negative regulation of immune system processGO:00026831360.013
response to axon injuryGO:004867810.013
gtp catabolic processGO:00061842370.013
vasculature developmentGO:00019441810.013
regulation of protein complex assemblyGO:00432541470.013
protein processingGO:00164852260.013
negative regulation of intracellular signal transductionGO:19025321830.013
neuron projection regenerationGO:003110210.013
maintenance of locationGO:00512351120.013
salivary gland morphogenesisGO:000743540.013
negative regulation of locomotionGO:00400131180.013
positive regulation of immune system processGO:00026842830.013
single organism cell adhesionGO:00986021790.013
embryonic placenta developmentGO:000189210.013
purine nucleotide biosynthetic processGO:0006164840.013
tripartite regional subdivisionGO:000735120.013
limbic system developmentGO:002176130.013
growthGO:00400072020.013
regulation of wnt signaling pathwayGO:00301111230.013
somatic stem cell maintenanceGO:003501940.013
regulation of axon guidanceGO:190266730.013
long term memoryGO:000761620.013
axon cargo transportGO:000808820.013
retinal ganglion cell axon guidanceGO:003129020.013
negative regulation of organelle organizationGO:00106391260.013
regulation of nervous system developmentGO:0051960880.013
non canonical wnt signaling pathway via mapk cascadeGO:003803040.013
endocytosisGO:00068971590.013
cell morphogenesis involved in differentiationGO:00009041440.013
gtp metabolic processGO:00460392390.013
cell activationGO:00017752130.013
epithelial tube branching involved in lung morphogenesisGO:006044140.013
behaviorGO:00076101120.013
glycoprotein metabolic processGO:00091001100.013
pattern specification involved in kidney developmentGO:006100410.013
dna repairGO:00062811980.013
regulation of cell adhesionGO:00301551660.013
regulation of protein catabolic processGO:00421761550.013
regulation of glial cell differentiationGO:004568530.013
regulation of meiotic cell cycleGO:005144540.013
regulation of protein serine threonine kinase activityGO:00719001790.012
synaptic vesicle exocytosisGO:001607930.012
cardiac muscle cell contractionGO:008600340.012
t cell selectionGO:004505840.012
regulation of ras protein signal transductionGO:00465781550.012
circadian behaviorGO:004851220.012
reactive oxygen species biosynthetic processGO:190340940.012
associative learningGO:000830610.012
regulation of nucleotide catabolic processGO:00308112050.012
response to woundingGO:00096111680.012
positive regulation of purine nucleotide catabolic processGO:00331231850.012
organic anion transportGO:00157111030.012
regulation of multi organism processGO:00439001570.012
multicellular organismal response to stressGO:003355510.012
pituitary gland developmentGO:002198320.012
cellular protein complex assemblyGO:00436231880.012
glycerolipid metabolic processGO:00464861070.012
regulation of vesicle mediated transportGO:00606271300.012
spermatid developmentGO:000728640.012
cell divisionGO:00513011680.012
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.012
ribose phosphate biosynthetic processGO:0046390820.012
matingGO:000761810.012
neuron developmentGO:00486661130.012
organic acid transportGO:0015849650.012
ribonucleoside monophosphate metabolic processGO:00091611870.012
regulation of microtubule based processGO:0032886740.012
regulation of sequence specific dna binding transcription factor activityGO:00510902110.012
cerebral cortex gabaergic interneuron differentiationGO:002189210.012
cell projection morphogenesisGO:00488581290.012
hindlimb morphogenesisGO:003513720.012
peptidyl tyrosine modificationGO:00182121700.012
synaptic vesicle recyclingGO:003646530.012
cyclic nucleotide biosynthetic processGO:0009190610.012
positive regulation of cell cycleGO:00457871400.012
receptor metabolic processGO:0043112810.012
regulation of protein processingGO:00706131500.012
microtubule cytoskeleton organizationGO:00002261760.012
nucleoside monophosphate metabolic processGO:00091231910.012
lipid biosynthetic processGO:00086101770.012
cellular response to cytokine stimulusGO:00713451810.012
regulation of neuroblast proliferationGO:190269230.012
cellular response to nitrogen compoundGO:19016991440.012
regulation of dephosphorylationGO:0035303960.012
regulation of synaptic plasticityGO:004816730.012
modification dependent macromolecule catabolic processGO:00436322120.012
ubiquitin dependent protein catabolic processGO:00065112060.012
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.012
regulation of glial cell proliferationGO:006025140.012
translationGO:00064121320.012
regulation of i kappab kinase nf kappab signalingGO:00431221620.012
establishment of tissue polarityGO:000716430.011
response to nitrogen compoundGO:19016981840.011
sensory perceptionGO:00076001030.011
negative regulation of transferase activityGO:00513481240.011
histone modificationGO:00165702510.011
ribonucleotide biosynthetic processGO:0009260810.011
rna processingGO:00063962550.011
somatic stem cell divisionGO:004810310.011
cellular amide metabolic processGO:0043603690.011
negative regulation of protein phosphorylationGO:00019331400.011
exocytosisGO:0006887710.011
negative regulation of cellular component movementGO:00512711060.011
regulation of cell cycle phase transitionGO:19019871260.011
epithelium migrationGO:00901321190.011
negative regulation of transportGO:00510511760.011
positive regulation of epithelial cell proliferation involved in wound healingGO:006005430.011
protein localization to plasma membraneGO:0072659930.011
small molecule biosynthetic processGO:00442831570.011
plasma membrane organizationGO:00070091150.011
divalent inorganic cation transportGO:00725111580.011
epithelial cell migrationGO:00106311190.011
embryonic forelimb morphogenesisGO:003511540.011
positive regulation of organelle organizationGO:00106381950.011
developmental programmed cell deathGO:001062330.011
positive regulation of cellular component biogenesisGO:00440891580.011
stress activated protein kinase signaling cascadeGO:0031098940.011
leukocyte differentiationGO:0002521980.011
reactive oxygen species metabolic processGO:0072593750.011
cyclic nucleotide metabolic processGO:0009187820.011
circulatory system processGO:00030131130.011
cell aggregationGO:009874310.011
cellular response to organonitrogen compoundGO:00714171240.011
single organism reproductive processGO:0044702980.011
regulation of axon extension involved in axon guidanceGO:004884120.011
atp metabolic processGO:00460341760.011
blood vessel morphogenesisGO:00485141620.011
peptidyl serine modificationGO:00182091060.011
positive regulation of cell developmentGO:0010720920.011
response to fungusGO:000962040.011
organelle assemblyGO:00709251760.011
tube closureGO:006060630.011
regulation of dna metabolic processGO:00510521530.011
response to biotic stimulusGO:00096072760.011
establishment of protein localization to organelleGO:00725941720.011
positive regulation of cytokine productionGO:00018191670.011
negative regulation of protein processingGO:00109551420.011
chromatin organizationGO:00063253510.011
embryo developmentGO:00097901230.011
cardiovascular system developmentGO:00723582620.011
positive regulation of neuroblast proliferationGO:000205220.011
regulation of reactive oxygen species biosynthetic processGO:190342630.011
copulationGO:000762010.011
regulation of protein maturationGO:19033171500.011
negative regulation of synaptic transmissionGO:005080520.011
anion transmembrane transportGO:0098656760.011
axis elongationGO:000340140.010
regulation of small gtpase mediated signal transductionGO:00510561560.010
wnt signaling pathway involved in wound healing spreading of epidermal cellsGO:003565910.010
thymus developmentGO:004853830.010
regulation of response to external stimulusGO:00321012220.010
visual behaviorGO:000763220.010
response to cytokineGO:00340972320.010
positive regulation of cortisol biosynthetic processGO:200006610.010
tissue regenerationGO:004224630.010
protein oligomerizationGO:00512591730.010
tube developmentGO:00352951250.010
ribonucleoside monophosphate catabolic processGO:00091581580.010
dopamine uptake involved in synaptic transmissionGO:005158340.010
prostate gland developmentGO:003085030.010
organelle localizationGO:0051640840.010
negative regulation of proteolysisGO:00458611320.010
sleepGO:003043120.010
cell cycle checkpointGO:00000751170.010
purine ribonucleotide biosynthetic processGO:0009152790.010
cerebellum developmentGO:002154920.010
sequestering of calcium ionGO:0051208170.010
establishment or maintenance of bipolar cell polarityGO:006124520.010
cell type specific apoptotic processGO:00972851250.010
camp metabolic processGO:0046058610.010
modification dependent protein catabolic processGO:00199412090.010
regulation of ras gtpase activityGO:00323181280.010
purine ribonucleoside monophosphate metabolic processGO:00091671860.010
phospholipid metabolic processGO:0006644990.010
protein autophosphorylationGO:00467771230.010
regulation of synaptic vesicle transportGO:190280330.010

PCSK1N disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:8634310.031
central nervous system diseaseDOID:3311860.031
musculoskeletal system diseaseDOID:172230.025
disease of metabolismDOID:00146672950.024
connective tissue diseaseDOID:651090.019
bone diseaseDOID:0080001880.019
sensory system diseaseDOID:00501552030.016
neurodegenerative diseaseDOID:12891020.015
inherited metabolic disorderDOID:6552420.015
disease of cellular proliferationDOID:145661740.014
brain diseaseDOID:936730.013
bone development diseaseDOID:0080006550.013
cancerDOID:1621670.012
disease of mental healthDOID:150700.011
eye and adnexa diseaseDOID:14921500.011
eye diseaseDOID:56141490.011
organ system cancerDOID:00506861640.011
cardiovascular system diseaseDOID:12871060.010