Homo sapiens

28 known processes

MMP15

matrix metallopeptidase 15 (membrane-inserted)

(Aliases: SMCP-2,MT2-MMP,MTMMP2)

MMP15 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
amine metabolic processGO:0009308440.136
purine nucleotide catabolic processGO:00061954050.128
small gtpase mediated signal transductionGO:0007264780.117
cellular amine metabolic processGO:0044106410.107
regulation of locomotionGO:00400123290.106
Human
nucleoside catabolic processGO:00091644080.106
regulation of cellular ketone metabolic processGO:0010565500.103
cell adhesionGO:00071553250.102
cellular ketone metabolic processGO:0042180800.100
cellular amino acid metabolic processGO:00065201160.097
ras protein signal transductionGO:0007265730.094
nucleoside triphosphate catabolic processGO:00091433940.091
purine ribonucleoside triphosphate metabolic processGO:00092054110.090
morphogenesis of embryonic epitheliumGO:001633140.090
glycosyl compound catabolic processGO:19016584130.090
ribonucleoside triphosphate catabolic processGO:00092033910.089
ribonucleotide catabolic processGO:00092614050.087
purine nucleoside triphosphate catabolic processGO:00091463920.087
purine nucleoside triphosphate metabolic processGO:00091444120.080
regulation of cellular amine metabolic processGO:0033238110.078
regulation of cellular amino acid metabolic processGO:000652160.076
ribonucleoside triphosphate metabolic processGO:00091994120.076
nucleoside triphosphate metabolic processGO:00091414220.075
purine ribonucleoside triphosphate catabolic processGO:00092073910.073
organophosphate catabolic processGO:00464344300.073
purine nucleoside catabolic processGO:00061523980.072
regulation of cell migrationGO:00303342890.072
Human
purine containing compound catabolic processGO:00725234110.072
regulation of cellular component movementGO:00512703340.071
Human
nucleoside phosphate catabolic processGO:19012924120.069
rho protein signal transductionGO:0007266260.069
purine ribonucleoside catabolic processGO:00461303980.068
regulation of nucleoside metabolic processGO:00091182090.067
membrane organizationGO:00610242920.066
ribonucleoside catabolic processGO:00424544060.066
purine ribonucleoside metabolic processGO:00461284370.064
purine ribonucleotide catabolic processGO:00091544040.064
gtp metabolic processGO:00460392390.064
nucleotide catabolic processGO:00091664080.064
post embryonic developmentGO:000979120.063
cellular component morphogenesisGO:00329893140.060
regulation of purine nucleotide catabolic processGO:00331212050.059
regulation of cell differentiationGO:00455953930.058
epithelium developmentGO:00604292270.057
positive regulation of cellular component organizationGO:00511303760.056
endomembrane system organizationGO:00102561960.056
female gamete generationGO:000729220.056
guanosine containing compound metabolic processGO:19010682440.055
positive regulation of cellular amine metabolic processGO:003324070.055
regulation of gtp catabolic processGO:00331241800.055
negative regulation of cell deathGO:00605483450.052
guanosine containing compound catabolic processGO:19010692390.052
actin filament based processGO:00300292240.051
lipid metabolic processGO:00066293810.051
positive regulation of hydrolase activityGO:00513453310.049
positive regulation of purine nucleotide metabolic processGO:19005442270.049
oogenesisGO:004847720.049
cellular lipid metabolic processGO:00442553030.049
regulation of purine nucleotide metabolic processGO:19005422640.049
cell projection organizationGO:00300302520.049
regulation of nucleotide metabolic processGO:00061402690.048
nervous system developmentGO:00073992930.048
positive regulation of locomotionGO:00400171860.048
Human
biological adhesionGO:00226103310.048
regulation of small gtpase mediated signal transductionGO:00510561560.048
single organism cellular localizationGO:19025803320.045
positive regulation of cellular catabolic processGO:00313312840.045
response to oxygen containing compoundGO:19017003690.045
Rat
negative regulation of catalytic activityGO:00430863350.045
negative regulation of phosphate metabolic processGO:00459362670.044
positive regulation of purine nucleotide catabolic processGO:00331231850.044
positive regulation of nucleotide catabolic processGO:00308131850.044
positive regulation of catabolic processGO:00098963100.043
cellular response to oxygen containing compoundGO:19017012760.043
chemical homeostasisGO:00488783060.043
positive regulation of cellular amino acid metabolic processGO:004576430.042
regulation of cell motilityGO:20001452990.042
Human
negative regulation of apoptotic processGO:00430663160.042
single organism membrane organizationGO:00448022680.042
cell developmentGO:00484683280.042
regulation of ras protein signal transductionGO:00465781550.042
gtp catabolic processGO:00061842370.042
positive regulation of gtpase activityGO:00435471660.041
circulatory system developmentGO:00723592620.041
negative regulation of developmental processGO:00510932470.041
negative regulation of phosphorus metabolic processGO:00105632670.041
cdc42 protein signal transductionGO:003248840.040
taxisGO:00423301570.040
cell morphogenesisGO:00009022960.040
negative regulation of locomotionGO:00400131180.040
organonitrogen compound biosynthetic processGO:19015662000.040
positive regulation of nucleoside metabolic processGO:00459791860.040
regulation of transferase activityGO:00513383550.039
protein localization to membraneGO:00726571600.039
multicellular organismal agingGO:001025930.039
anatomical structure formation involved in morphogenesisGO:00486462840.039
cation transportGO:00068123310.039
immune responseGO:00069553070.038
enzyme linked receptor protein signaling pathwayGO:00071673030.038
organ morphogenesisGO:00098871470.038
negative regulation of cellular protein metabolic processGO:00322693530.038
determination of adult lifespanGO:000834020.037
positive regulation of ras gtpase activityGO:00323201170.037
cell fate determinationGO:000170930.037
peptidyl tyrosine modificationGO:00182121700.037
negative regulation of protein metabolic processGO:00512483910.037
negative regulation of programmed cell deathGO:00430693210.037
regulation of protein kinase activityGO:00458592890.036
negative regulation of cellular component movementGO:00512711060.036
positive regulation of nucleotide metabolic processGO:00459812300.036
mapk cascadeGO:00001652880.036
regulation of anatomical structure morphogenesisGO:00226032860.035
negative regulation of cell motilityGO:20001461040.035
regulation of gtpase activityGO:00430871800.035
positive regulation of cell motilityGO:20001471770.035
Human
signal transduction by phosphorylationGO:00230142970.035
negative regulation of cell migrationGO:00303361020.035
positive regulation of phosphorylationGO:00423273940.035
chemotaxisGO:00069351570.035
regulation of mapk cascadeGO:00434082620.034
tissue migrationGO:00901301190.034
segmentationGO:003528240.034
regulation of ras gtpase activityGO:00323181280.033
regulation of cytoskeleton organizationGO:00514931770.033
oocyte differentiationGO:000999420.033
cardiovascular system developmentGO:00723582620.033
carbohydrate derivative biosynthetic processGO:19011372070.032
locomotory behaviorGO:000762610.032
cellular response to endogenous stimulusGO:00714953360.032
regulation of nucleotide catabolic processGO:00308112050.032
positive regulation of protein phosphorylationGO:00019343130.032
positive regulation of cell migrationGO:00303351720.032
Human
regulation of cell adhesionGO:00301551660.032
regulation of protein localizationGO:00328802960.032
positive regulation of developmental processGO:00510943140.031
peptidyl tyrosine phosphorylationGO:00181081700.031
regulation of kinase activityGO:00435493140.031
negative regulation of multicellular organismal processGO:00512413170.031
ion transmembrane transportGO:00342203380.031
regulation of cellular component biogenesisGO:00440872810.031
vesicle mediated transportGO:00161923710.031
regulation of rho protein signal transductionGO:0035023790.031
response to abiotic stimulusGO:00096283360.031
regulation of proteolysisGO:00301622930.031
positive regulation of gtp catabolic processGO:00331261660.030
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.030
negative regulation of hydrolase activityGO:00513461820.030
epithelium migrationGO:00901321190.030
system processGO:00030083490.030
secretionGO:00469032540.030
cytoplasmic transportGO:00164823790.029
innate immune responseGO:00450871780.029
transmembrane transportGO:00550853990.029
wound healingGO:00420601150.028
positive regulation of immune system processGO:00026842830.028
blastoderm segmentationGO:000735020.028
regulation of establishment of protein localizationGO:00702012420.028
single organismal cell cell adhesionGO:00163371480.028
single organism cell adhesionGO:00986021790.027
plasma membrane organizationGO:00070091150.027
regulation of response to external stimulusGO:00321012220.027
organic hydroxy compound metabolic processGO:19016151470.027
peripheral nervous system developmentGO:000742220.026
regulation of cellular response to stressGO:00801352440.025
nitrogen compound transportGO:00717051910.025
positive regulation of cell differentiationGO:00455972110.025
regenerationGO:003109940.025
motor neuron axon guidanceGO:000804520.025
regulation of rho gtpase activityGO:0032319660.025
establishment of protein localization to membraneGO:00901501210.025
positive regulation of cell proliferationGO:00082843010.025
regulation of peptidyl tyrosine phosphorylationGO:00507301080.025
response to lipidGO:00339932060.025
Rat
actin cytoskeleton organizationGO:00300362070.025
protein maturationGO:00516042330.025
immune system developmentGO:00025201950.025
response to growth factorGO:00708482050.025
memoryGO:000761330.024
lipid biosynthetic processGO:00086101770.024
positive regulation of transportGO:00510503360.024
neuromuscular junction developmentGO:000752830.024
apoptotic signaling pathwayGO:00971902680.024
positive regulation of cell deathGO:00109422630.024
cellular macromolecular complex assemblyGO:00346223240.024
oocyte developmentGO:004859910.024
negative regulation of cellular component organizationGO:00511292350.024
regulation of cell cycleGO:00517263930.024
cell morphogenesis involved in differentiationGO:00009041440.024
ameboidal type cell migrationGO:00016671350.024
regulation of cell cycle processGO:00105642660.024
single organism carbohydrate metabolic processGO:00447231930.024
positive regulation of cellular component movementGO:00512721810.023
Human
negative regulation of protein modification processGO:00314002000.023
cation homeostasisGO:00550801890.023
cell substrate adhesionGO:00315891320.023
ion homeostasisGO:00508012300.023
cell projection morphogenesisGO:00488581290.023
protein localization to plasma membraneGO:0072659930.023
protein catabolic processGO:00301633250.022
regulation of actin filament based processGO:00329701410.022
dephosphorylationGO:00163112090.022
epithelial cell differentiationGO:00308551410.022
organophosphate biosynthetic processGO:00904071630.022
hematopoietic or lymphoid organ developmentGO:00485341860.022
embryonic epithelial tube formationGO:000183840.022
metal ion transportGO:00300012720.022
regulation of defense responseGO:00313471540.021
cellular homeostasisGO:00197251960.021
neurogenesisGO:00220081690.021
defense responseGO:00069523150.021
compound eye developmentGO:004874910.021
anterior posterior axis specificationGO:000994820.021
cell activationGO:00017752130.021
negative regulation of transferase activityGO:00513481240.021
protein processingGO:00164852260.021
cell matrix adhesionGO:0007160850.020
regulation of sequence specific dna binding transcription factor activityGO:00510902110.020
neurological system processGO:00508771630.020
cell part morphogenesisGO:00329901370.020
cellular response to growth factor stimulusGO:00713631970.020
regulation of growthGO:00400081650.020
Human
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.020
regulation of intracellular transportGO:00323861950.020
blood vessel developmentGO:00015681720.020
regulation of axon guidanceGO:190266730.020
cytokine productionGO:00018162470.020
blood vessel morphogenesisGO:00485141620.020
neural tube formationGO:000184130.020
regulation of actin cytoskeleton organizationGO:00329561160.020
response to other organismGO:00517072610.020
regulation of hormone levelsGO:00108171250.020
positive regulation of apoptotic processGO:00430652460.020
neuron differentiationGO:00301821380.020
epithelial cell migrationGO:00106311190.019
negative regulation of cellular amine metabolic processGO:003323930.019
regulation of cytokine productionGO:00018172320.019
negative regulation of phosphorylationGO:00423261740.019
ribonucleoside monophosphate metabolic processGO:00091611870.019
intracellular protein transportGO:00068862700.019
cellular macromolecule catabolic processGO:00442653800.019
response to external biotic stimulusGO:00432072610.019
protein ubiquitinationGO:00165673140.019
cell type specific apoptotic processGO:00972851250.019
protein modification by small protein conjugationGO:00324463420.019
carbohydrate metabolic processGO:00059752070.019
regulation of microtubule based processGO:0032886740.019
positive regulation of cellular component biogenesisGO:00440891580.019
response to biotic stimulusGO:00096072760.019
monocarboxylic acid metabolic processGO:00327871850.019
cellular chemical homeostasisGO:00550821800.018
mitotic cell cycle processGO:19030472860.018
nucleoside monophosphate metabolic processGO:00091231910.018
negative regulation of proteolysisGO:00458611320.018
positive regulation of programmed cell deathGO:00430682490.018
regulation of immune responseGO:00507762010.018
retinal ganglion cell axon guidanceGO:003129020.018
spermatid developmentGO:000728640.018
response to organonitrogen compoundGO:00102431560.018
negative regulation of intracellular signal transductionGO:19025321830.018
melanin metabolic processGO:000658210.018
microtubule based processGO:00070172100.018
neuron developmentGO:00486661130.018
spermatid differentiationGO:004851540.018
cellular response to dna damage stimulusGO:00069743790.018
organelle assemblyGO:00709251760.018
glycoprotein metabolic processGO:00091001100.018
negative regulation of protein maturationGO:19033181420.018
negative regulation of cell cycleGO:00457861930.018
positive regulation of rho gtpase activityGO:0032321560.018
negative regulation of protein phosphorylationGO:00019331400.018
endocytosisGO:00068971590.018
sensory perception of painGO:001923340.018
generation of neuronsGO:00486991520.018
maintenance of locationGO:00512351120.018
regulation of cell developmentGO:00602841610.018
angiogenesisGO:00015251470.017
neuron projection developmentGO:00311751060.017
negative regulation of cellular amino acid metabolic processGO:004576320.017
metal ion homeostasisGO:00550651690.017
multi organism cellular processGO:00447641560.017
inner ear morphogenesisGO:004247240.017
protein localization to organelleGO:00333652800.017
cell junction organizationGO:0034330790.017
viral processGO:00160321460.017
mitotic cell cycleGO:00002783260.017
reactive oxygen species metabolic processGO:0072593750.017
growthGO:00400072020.017
Human
cell cycle phase transitionGO:00447701730.017
epithelial cell proliferationGO:00506731280.017
regulation of protein maturationGO:19033171500.017
positive regulation of protein kinase activityGO:00458601900.017
central nervous system developmentGO:00074171230.017
secretion by cellGO:00329402260.017
vasculature developmentGO:00019441810.017
atp metabolic processGO:00460341760.017
somatic stem cell maintenanceGO:003501940.016
hindbrain developmentGO:003090230.016
regulation of protein processingGO:00706131500.016
tissue morphogenesisGO:0048729960.016
purine ribonucleoside monophosphate metabolic processGO:00091671860.016
small molecule biosynthetic processGO:00442831570.016
regulation of secretionGO:00510461940.016
leukocyte activationGO:00453211640.016
cell growthGO:00160491600.016
Human
protein autophosphorylationGO:00467771230.016
response to hormoneGO:00097251750.016
Rat
microtubule cytoskeleton organizationGO:00002261760.016
negative regulation of kinase activityGO:00336731060.016
regulation of peptidase activityGO:00525471800.016
organ formationGO:004864530.016
alcohol metabolic processGO:00060661140.016
cell projection assemblyGO:00300311260.016
regulation of multi organism processGO:00439001570.016
negative regulation of transportGO:00510511760.016
symbiosis encompassing mutualism through parasitismGO:00444031560.016
response to woundingGO:00096111680.016
purine nucleoside monophosphate metabolic processGO:00091261860.016
anion transportGO:00068201610.016
regulation of ion transportGO:00432691890.016
negative regulation of protein processingGO:00109551420.016
i kappab kinase nf kappab signalingGO:00072491660.016
skin developmentGO:0043588760.016
leukocyte migrationGO:00509001070.016
cellular protein catabolic processGO:00442572610.016
response to cytokineGO:00340972320.015
inorganic ion transmembrane transportGO:00986602310.015
regulation of body fluid levelsGO:0050878990.015
cell chemotaxisGO:00603261120.015
negative regulation of protein kinase activityGO:0006469980.015
regulation of cell growthGO:00015581350.015
Human
cellular protein complex assemblyGO:00436231880.015
immune effector processGO:00022521590.015
regulation of stress activated protein kinase signaling cascadeGO:0070302850.015
spinal cord developmentGO:002151040.015
viral life cycleGO:00190581320.015
regulation of synaptic plasticityGO:004816730.015
embryo developmentGO:00097901230.015
regulation of cell projection organizationGO:00313441070.015
purine nucleoside monophosphate catabolic processGO:00091281580.015
regulation of apoptotic signaling pathwayGO:20012331750.015
regulation of protein serine threonine kinase activityGO:00719001790.015
oxidation reduction processGO:00551143960.015
positive regulation of kinase activityGO:00336742040.015
salivary gland morphogenesisGO:000743540.015
positive regulation of transferase activityGO:00513472270.015
erk1 and erk2 cascadeGO:00703711040.015
regulation of erk1 and erk2 cascadeGO:0070372990.015
protein targetingGO:00066051870.015
blood vessel endothelial cell migrationGO:0043534420.015
phospholipid metabolic processGO:0006644990.014
regulation of secretion by cellGO:19035301770.014
developmental programmed cell deathGO:001062330.014
regulation of cell morphogenesisGO:00226041530.014
glycoprotein biosynthetic processGO:0009101910.014
negative regulation of cell proliferationGO:00082852280.014
negative regulation of cell differentiationGO:00455961710.014
organic anion transportGO:00157111030.014
regulation of endopeptidase activityGO:00525481700.014
regulation of bindingGO:00510981110.014
morphogenesis of an epitheliumGO:0002009600.014
head developmentGO:00603221080.014
proteolysis involved in cellular protein catabolic processGO:00516032440.014
adult locomotory behaviorGO:000834410.014
embryonic placenta developmentGO:000189210.014
stress activated mapk cascadeGO:0051403930.014
glycerolipid metabolic processGO:00464861070.014
cation transmembrane transportGO:00986552380.014
regulation of protein complex assemblyGO:00432541470.014
multicellular organismal response to stressGO:003355510.014
mitochondrion organizationGO:00070051560.014
regulation of protein transportGO:00512232130.014
brain developmentGO:0007420970.014
skeletal system developmentGO:0001501790.014
primary neural tube formationGO:001402030.014
actin filament organizationGO:00070151280.014
tripartite regional subdivisionGO:000735120.014
organic acid biosynthetic processGO:0016053970.014
tube closureGO:006060630.014
cellular cation homeostasisGO:00300031630.013
positive regulation of secretionGO:00510471160.013
positive regulation of immune responseGO:00507781590.013
cell cell signalingGO:00072671550.013
hemopoiesisGO:00300971800.013
sulfur compound metabolic processGO:00067901010.013
divalent inorganic cation transportGO:00725111580.013
protein oligomerizationGO:00512591730.013
nucleoside monophosphate catabolic processGO:00091251590.013
regulation of dephosphorylationGO:0035303960.013
calcium ion transportGO:00068161470.013
chromatin organizationGO:00063253510.013
regulation of i kappab kinase nf kappab signalingGO:00431221620.013
positive regulation of organelle organizationGO:00106381950.013
mitotic cell cycle phase transitionGO:00447721620.013
morphogenesis of a polarized epitheliumGO:000173830.013
cell cell junction organizationGO:0045216690.013
regulation of protein catabolic processGO:00421761550.013
anterior posterior axis specification embryoGO:000859520.013
negative regulation of peptidase activityGO:0010466910.013
regulation of neural precursor cell proliferationGO:200017740.013
positive regulation of i kappab kinase nf kappab signalingGO:00431231320.013
cellular response to cytokine stimulusGO:00713451810.013
histone modificationGO:00165702510.013
glial cell migrationGO:000834740.013
sequestering of metal ionGO:0051238240.013
negative regulation of protein serine threonine kinase activityGO:0071901570.013
response to radiationGO:00093141510.013
monovalent inorganic cation transportGO:00156721280.013
mesonephric duct developmentGO:007217730.013
regulation of neurogenesisGO:0050767820.013
proteasomal protein catabolic processGO:00104981760.013
tissue regenerationGO:004224630.013
regulation of chemotaxisGO:0050920740.013
endothelial cell migrationGO:0043542860.013
positive regulation of cytokine productionGO:00018191670.013
stress activated protein kinase signaling cascadeGO:0031098940.013
sodium ion transportGO:0006814610.013
oocyte maturationGO:000155610.013
regulation of anatomical structure sizeGO:00900661010.013
nucleoside phosphate biosynthetic processGO:19012931090.013
regulation of reactive oxygen species metabolic processGO:2000377410.012
cellular response to abiotic stimulusGO:00712141170.012
sequestering of calcium ionGO:0051208170.012
neuroblast proliferationGO:000740540.012
regulation of epithelial cell proliferationGO:00506781130.012
positive regulation of secretion by cellGO:19035321080.012
regulation of vasculature developmentGO:1901342970.012
posttranscriptional regulation of gene expressionGO:00106082130.012
positive regulation of peptidyl tyrosine phosphorylationGO:0050731850.012
modification dependent macromolecule catabolic processGO:00436322120.012
positive regulation of mapk cascadeGO:00434101900.012
regulation of protein localization to plasma membraneGO:1903076400.012
lipid transportGO:0006869900.012
regulation of vesicle mediated transportGO:00606271300.012
nucleotide biosynthetic processGO:00091651090.012
neural tube closureGO:000184330.012
regulation of epithelial cell migrationGO:0010632930.012
regulation of cytoplasmic transportGO:19036491490.012
myeloid cell differentiationGO:00300991170.012
circulatory system processGO:00030131130.012
neurotransmitter secretionGO:000726940.012
neural crest cell developmentGO:001403230.012
positive regulation of ion transportGO:0043270870.012
modification dependent protein catabolic processGO:00199412090.012
stem cell divisionGO:001714520.012
regulation of nervous system developmentGO:0051960880.012
regulation of cell morphogenesis involved in differentiationGO:0010769830.012
ribonucleoside monophosphate catabolic processGO:00091581580.012
regulation of wnt signaling pathwayGO:00301111230.012
nucleocytoplasmic transportGO:00069131760.012
regulation of cysteine type endopeptidase activityGO:20001161270.012
negative regulation of axonogenesisGO:005077140.012
sensory perception of smellGO:000760820.012
atp catabolic processGO:00062001570.012
regulation of mitotic cell cycleGO:00073461890.012
positive regulation of rac gtpase activityGO:0032855310.012
reactive nitrogen species metabolic processGO:200105730.012
purine ribonucleoside monophosphate catabolic processGO:00091691580.012
sensory perceptionGO:00076001030.012
outflow tract septum morphogenesisGO:000314840.012
reactive oxygen species biosynthetic processGO:190340940.012
negative regulation of endopeptidase activityGO:0010951840.012
regulation of metal ion transportGO:00109591200.012
purine containing compound biosynthetic processGO:0072522880.012
cellular ion homeostasisGO:00068731680.012
rhythmic behaviorGO:000762220.012
regulation of protein kinase b signalingGO:0051896610.012
ubiquitin dependent protein catabolic processGO:00065112060.011
cellular component disassemblyGO:0022411920.011
interspecies interaction between organismsGO:00444191560.011
regulation of innate immune responseGO:0045088970.011
cellular response to lipidGO:00713961270.011
regulation of homeostatic processGO:00328441210.011
glycerophospholipid metabolic processGO:0006650840.011
wnt signaling pathwayGO:00160551560.011
jnk cascadeGO:0007254800.011
negative regulation of catabolic processGO:00098951040.011
regulation of behaviorGO:0050795820.011
negative regulation of synaptic transmissionGO:005080520.011
regulation of phosphatase activityGO:0010921810.011
establishment of protein localization to plasma membraneGO:0090002680.011
renal system developmentGO:0072001630.011

MMP15 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:00146672950.035
inherited metabolic disorderDOID:6552420.032
cancerDOID:1621670.023
organ system cancerDOID:00506861640.023
disease of cellular proliferationDOID:145661740.023
musculoskeletal system diseaseDOID:172230.021
nervous system diseaseDOID:8634310.018
sensory system diseaseDOID:00501552030.018
central nervous system diseaseDOID:3311860.018
cardiovascular system diseaseDOID:12871060.017
connective tissue diseaseDOID:651090.015
neurodegenerative diseaseDOID:12891020.012