Homo sapiens

7 known processes

MMACHC

methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria

(Aliases: cblC,DKFZp564I122,RP11-291L19.3,FLJ25671)

MMACHC biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
post embryonic developmentGO:000979120.080
cellular ketone metabolic processGO:0042180800.059
cellular amino acid metabolic processGO:00065201160.050
small molecule biosynthetic processGO:00442831570.046
determination of adult lifespanGO:000834020.042
cofactor metabolic processGO:0051186870.039
amine metabolic processGO:0009308440.037
multicellular organismal agingGO:001025930.037
regulation of cellular amino acid metabolic processGO:000652160.036
cellular amine metabolic processGO:0044106410.035
regulation of cellular ketone metabolic processGO:0010565500.033
regulation of cellular amine metabolic processGO:0033238110.032
positive regulation of cellular amino acid metabolic processGO:004576430.032
carbohydrate metabolic processGO:00059752070.029
locomotory behaviorGO:000762610.029
organonitrogen compound biosynthetic processGO:19015662000.029
glycerol metabolic processGO:000607140.028
cellular macromolecule catabolic processGO:00442653800.027
negative regulation of protein metabolic processGO:00512483910.027
cytoplasmic transportGO:00164823790.027
negative regulation of catalytic activityGO:00430863350.026
cellular lipid metabolic processGO:00442553030.026
negative regulation of cellular protein metabolic processGO:00322693530.026
positive regulation of cellular amine metabolic processGO:003324070.026
cellular response to dna damage stimulusGO:00069743790.026
single organism cellular localizationGO:19025803320.025
female gamete generationGO:000729220.025
single organism carbohydrate metabolic processGO:00447231930.025
transmembrane transportGO:00550853990.025
mitochondrion organizationGO:00070051560.024
organophosphate catabolic processGO:00464344300.024
protein catabolic processGO:00301633250.024
neuromuscular junction developmentGO:000752830.024
regulation of proteolysisGO:00301622930.023
positive regulation of catabolic processGO:00098963100.023
protein localization to organelleGO:00333652800.023
cellular protein catabolic processGO:00442572610.023
positive regulation of hydrolase activityGO:00513453310.023
nucleoside triphosphate metabolic processGO:00091414220.022
segmentationGO:003528240.022
regulation of transferase activityGO:00513383550.022
single organism membrane organizationGO:00448022680.022
purine ribonucleoside metabolic processGO:00461284370.022
oogenesisGO:004847720.021
protein maturationGO:00516042330.021
nucleoside phosphate catabolic processGO:19012924120.021
immune responseGO:00069553070.021
cellular macromolecular complex assemblyGO:00346223240.021
negative regulation of phosphorus metabolic processGO:00105632670.020
negative regulation of programmed cell deathGO:00430693210.020
carboxylic acid biosynthetic processGO:0046394970.020
coenzyme metabolic processGO:0006732650.020
negative regulation of cell deathGO:00605483450.020
regulation of peptidase activityGO:00525471800.020
negative regulation of protein modification processGO:00314002000.020
memoryGO:000761330.020
nucleoside triphosphate catabolic processGO:00091433940.020
defense responseGO:00069523150.019
cell morphogenesisGO:00009022960.019
purine containing compound catabolic processGO:00725234110.019
positive regulation of programmed cell deathGO:00430682490.019
posttranscriptional regulation of gene expressionGO:00106082130.019
nucleotide catabolic processGO:00091664080.019
anterior posterior axis specificationGO:000994820.019
protein processingGO:00164852260.019
monocarboxylic acid metabolic processGO:00327871850.018
response to oxygen containing compoundGO:19017003690.018
cofactor biosynthetic processGO:0051188310.018
lipid metabolic processGO:00066293810.018
regulation of protein kinase activityGO:00458592890.018
oocyte developmentGO:004859910.018
chemical homeostasisGO:00488783060.018
intracellular protein transportGO:00068862700.018
glycosyl compound catabolic processGO:19016584130.018
regulation of kinase activityGO:00435493140.018
proteolysis involved in cellular protein catabolic processGO:00516032440.018
regenerationGO:003109940.018
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.018
apoptotic signaling pathwayGO:00971902680.018
purine nucleoside triphosphate metabolic processGO:00091444120.017
negative regulation of phosphorylationGO:00423261740.017
positive regulation of cell deathGO:00109422630.017
maintenance of locationGO:00512351120.017
membrane organizationGO:00610242920.017
negative regulation of phosphate metabolic processGO:00459362670.017
cellular component morphogenesisGO:00329893140.017
negative regulation of apoptotic processGO:00430663160.017
regulation of cellular response to stressGO:00801352440.017
purine nucleoside catabolic processGO:00061523980.017
response to abiotic stimulusGO:00096283360.017
protein ubiquitinationGO:00165673140.017
ribonucleoside triphosphate catabolic processGO:00092033910.017
negative regulation of cellular amine metabolic processGO:003323930.017
adult locomotory behaviorGO:000834410.017
positive regulation of cellular catabolic processGO:00313312840.017
positive regulation of cellular component organizationGO:00511303760.017
negative regulation of intracellular signal transductionGO:19025321830.017
innate immune responseGO:00450871780.017
chromatin organizationGO:00063253510.016
actin filament based processGO:00300292240.016
ribonucleotide catabolic processGO:00092614050.016
negative regulation of cellular amino acid metabolic processGO:004576320.016
purine ribonucleoside triphosphate catabolic processGO:00092073910.016
ras protein signal transductionGO:0007265730.016
blastoderm segmentationGO:000735020.016
regulation of purine nucleotide metabolic processGO:19005422640.016
lipid biosynthetic processGO:00086101770.016
positive regulation of phosphorylationGO:00423273940.016
histone modificationGO:00165702510.016
protein modification by small protein conjugationGO:00324463420.016
protein targetingGO:00066051870.016
cellular response to oxygen containing compoundGO:19017012760.016
positive regulation of apoptotic processGO:00430652460.015
organic hydroxy compound metabolic processGO:19016151470.015
protein localization to membraneGO:00726571600.015
purine nucleotide catabolic processGO:00061954050.015
regulation of cell cycleGO:00517263930.015
negative regulation of cellular component organizationGO:00511292350.015
hindbrain developmentGO:003090230.015
response to cytokineGO:00340972320.015
ion transmembrane transportGO:00342203380.015
regulation of protein localizationGO:00328802960.015
purine ribonucleoside triphosphate metabolic processGO:00092054110.015
ribonucleoside triphosphate metabolic processGO:00091994120.015
dephosphorylationGO:00163112090.015
negative regulation of hydrolase activityGO:00513461820.015
establishment of protein localization to organelleGO:00725941720.015
rna interferenceGO:001624640.015
negative regulation of cell proliferationGO:00082852280.015
mitotic cell cycleGO:00002783260.015
regulation of nucleoside metabolic processGO:00091182090.015
regulation of nucleotide metabolic processGO:00061402690.015
morphogenesis of embryonic epitheliumGO:001633140.014
regulation of i kappab kinase nf kappab signalingGO:00431221620.014
regulation of endopeptidase activityGO:00525481700.014
positive regulation of immune system processGO:00026842830.014
vesicle mediated transportGO:00161923710.014
negative regulation of protein maturationGO:19033181420.014
regulation of establishment of protein localizationGO:00702012420.014
ribonucleoside catabolic processGO:00424544060.014
cation transportGO:00068123310.014
ion homeostasisGO:00508012300.014
organophosphate biosynthetic processGO:00904071630.014
spermatid differentiationGO:004851540.014
positive regulation of transportGO:00510503360.014
oxidation reduction processGO:00551143960.014
cellular response to cytokine stimulusGO:00713451810.014
covalent chromatin modificationGO:00165692540.014
spermatid developmentGO:000728640.014
oocyte differentiationGO:000999420.014
cell growthGO:00160491600.014
positive regulation of purine nucleotide metabolic processGO:19005442270.014
nuclear transportGO:00511691790.014
anterior posterior axis specification embryoGO:000859520.014
compound eye developmentGO:004874910.014
purine ribonucleotide catabolic processGO:00091544040.014
metencephalon developmentGO:002203720.014
small gtpase mediated signal transductionGO:0007264780.014
dna repairGO:00062811980.014
system processGO:00030083490.014
regulation of cell growthGO:00015581350.014
reactive oxygen species biosynthetic processGO:190340940.014
rho protein signal transductionGO:0007266260.013
purine ribonucleoside catabolic processGO:00461303980.013
peripheral nervous system developmentGO:000742220.013
organic acid biosynthetic processGO:0016053970.013
cellular protein complex assemblyGO:00436231880.013
regulation of protein catabolic processGO:00421761550.013
nucleoside catabolic processGO:00091644080.013
response to external biotic stimulusGO:00432072610.013
cellular response to endogenous stimulusGO:00714953360.013
cation transmembrane transportGO:00986552380.013
signal transduction by phosphorylationGO:00230142970.013
tripartite regional subdivisionGO:000735120.013
regulation of cell cycle processGO:00105642660.013
carbohydrate derivative biosynthetic processGO:19011372070.013
purine nucleoside triphosphate catabolic processGO:00091463920.013
positive regulation of nucleotide metabolic processGO:00459812300.013
reactive nitrogen species metabolic processGO:200105730.013
response to biotic stimulusGO:00096072760.013
modification dependent macromolecule catabolic processGO:00436322120.013
positive regulation of nucleoside metabolic processGO:00459791860.013
regulation of response to external stimulusGO:00321012220.013
quinone metabolic processGO:1901661180.013
anatomical structure formation involved in morphogenesisGO:00486462840.013
regulation of purine nucleotide catabolic processGO:00331212050.013
chromatin modificationGO:00165682980.013
negative regulation of cell cycleGO:00457861930.013
guanosine containing compound catabolic processGO:19010692390.013
cell projection organizationGO:00300302520.013
negative regulation of protein processingGO:00109551420.013
ribonucleoside monophosphate metabolic processGO:00091611870.013
biological adhesionGO:00226103310.013
cytokine productionGO:00018162470.012
secretionGO:00469032540.012
neurotransmitter secretionGO:000726940.012
negative regulation of protein phosphorylationGO:00019331400.012
ncrna metabolic processGO:00346601080.012
cellular carbohydrate metabolic processGO:0044262840.012
regulation of protein maturationGO:19033171500.012
negative regulation of multicellular organismal processGO:00512413170.012
regulation of protein transportGO:00512232130.012
regulation of immune responseGO:00507762010.012
glycoprotein metabolic processGO:00091001100.012
release of cytoplasmic sequestered nf kappabGO:000858840.012
regulation of sequence specific dna binding transcription factor activityGO:00510902110.012
regulation of cell differentiationGO:00455953930.012
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.012
positive regulation of cell proliferationGO:00082843010.012
regulation of apoptotic signaling pathwayGO:20012331750.012
nucleocytoplasmic transportGO:00069131760.012
positive regulation of purine nucleotide catabolic processGO:00331231850.012
negative regulation of transferase activityGO:00513481240.012
regulation of anatomical structure morphogenesisGO:00226032860.012
embryonic epithelial tube formationGO:000183840.012
regulation of cysteine type endopeptidase activityGO:20001161270.012
proteasomal protein catabolic processGO:00104981760.012
regulation of cell motilityGO:20001452990.012
positive regulation of nucleotide catabolic processGO:00308131850.012
regulation of intracellular transportGO:00323861950.012
cell adhesionGO:00071553250.012
fatty acid metabolic processGO:00066311150.012
regulation of gtp catabolic processGO:00331241800.012
regulation of cytokine productionGO:00018172320.012
secretion by cellGO:00329402260.012
positive regulation of developmental processGO:00510943140.012
negative regulation of proteolysisGO:00458611320.012
response to fungusGO:000962040.012
associative learningGO:000830610.012
inorganic ion transmembrane transportGO:00986602310.012
nervous system developmentGO:00073992930.012
ketone biosynthetic processGO:0042181170.012
cellular homeostasisGO:00197251960.012
inorganic cation transmembrane transportGO:00986621940.012
regulation of protein processingGO:00706131500.012
establishment of protein localization to membraneGO:00901501210.012
positive regulation of organelle organizationGO:00106381950.012
regulation of reactive oxygen species biosynthetic processGO:190342630.012
response to other organismGO:00517072610.011
inner ear morphogenesisGO:004247240.011
regulation of cytoskeleton organizationGO:00514931770.011
regulation of secretionGO:00510461940.011
metal ion transportGO:00300012720.011
microtubule based processGO:00070172100.011
monocarboxylic acid biosynthetic processGO:0072330670.011
regulation of cellular component movementGO:00512703340.011
coenzyme biosynthetic processGO:0009108240.011
regulation of dna metabolic processGO:00510521530.011
mapk cascadeGO:00001652880.011
positive regulation of proteolysisGO:00458621420.011
cell projection assemblyGO:00300311260.011
regulation of nucleotide catabolic processGO:00308112050.011
nerve developmentGO:002167540.011
organ formationGO:004864530.011
negative regulation of organelle organizationGO:00106391260.011
anion transportGO:00068201610.011
response to axon injuryGO:004867810.011
gtp metabolic processGO:00460392390.011
cardiac muscle cell contractionGO:008600340.011
alpha amino acid metabolic processGO:1901605720.011
mitotic cell cycle processGO:19030472860.011
organic acid catabolic processGO:0016054710.011
regulation of synaptic plasticityGO:004816730.011
positive regulation of protein phosphorylationGO:00019343130.011
organelle assemblyGO:00709251760.011
small molecule catabolic processGO:0044282920.011
negative regulation of transportGO:00510511760.011
actin mediated cell contractionGO:0070252120.011
response to lipidGO:00339932060.011
rna processingGO:00063962550.011
translationGO:00064121320.011
growthGO:00400072020.011
microtubule cytoskeleton organizationGO:00002261760.011
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.011
negative regulation of immune system processGO:00026831360.010
guanosine containing compound metabolic processGO:19010682440.010
reactive oxygen species metabolic processGO:0072593750.010
cation homeostasisGO:00550801890.010
cellular cation homeostasisGO:00300031630.010
tissue regenerationGO:004224630.010
regulation of neural precursor cell proliferationGO:200017740.010
regulation of secretion by cellGO:19035301770.010
sulfur compound metabolic processGO:00067901010.010
rhythmic behaviorGO:000762220.010
methylationGO:00322591060.010
syncytium formation by plasma membrane fusionGO:000076820.010
photoreceptor cell differentiationGO:004653020.010
motor neuron axon guidanceGO:000804520.010
positive regulation of transferase activityGO:00513472270.010
negative regulation of protein kinase activityGO:0006469980.010
response to organic cyclic compoundGO:00140702040.010
cellular chemical homeostasisGO:00550821800.010
positive regulation of gtpase activityGO:00435471660.010
gtp catabolic processGO:00061842370.010
tube closureGO:006060630.010
regulation of locomotionGO:00400123290.010
regulation of cellular component biogenesisGO:00440872810.010
positive regulation of gtp catabolic processGO:00331261660.010
cilium morphogenesisGO:0060271750.010
spinal cord developmentGO:002151040.010
epithelium developmentGO:00604292270.010
morphogenesis of a polarized epitheliumGO:000173830.010
regulation of mapk cascadeGO:00434082620.010

MMACHC disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
inherited metabolic disorderDOID:6552420.140
disease of metabolismDOID:00146672950.140
central nervous system diseaseDOID:3311860.020
nervous system diseaseDOID:8634310.020
carbohydrate metabolic disorderDOID:2978550.019
neurodegenerative diseaseDOID:12891020.017
musculoskeletal system diseaseDOID:172230.017
sensory system diseaseDOID:00501552030.017
disease of cellular proliferationDOID:145661740.016
cancerDOID:1621670.016
organ system cancerDOID:00506861640.016
immune system diseaseDOID:29141550.015
amino acid metabolic disorderDOID:9252500.013
eye and adnexa diseaseDOID:14921500.013
eye diseaseDOID:56141490.013
muscular diseaseDOID:00800001140.011
muscle tissue diseaseDOID:661130.011
connective tissue diseaseDOID:651090.011
retinal diseaseDOID:56791180.011
hematopoietic system diseaseDOID:741000.010
myopathyDOID:4231040.010
organic acidemiaDOID:0060159140.003
methylmalonic acidemiaDOID:1474950.001