Homo sapiens

16 known processes

NEDD8

neural precursor cell expressed, developmentally down-regulated 8

(Aliases: MGC125897,FLJ43224,NEDD-8,MGC104393,MGC125896)

NEDD8 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
protein ubiquitinationGO:00165673140.998
Fly
protein modification by small protein conjugationGO:00324463420.997
protein modification by small protein removalGO:0070646920.995
protein neddylationGO:004511670.979
cellular macromolecule catabolic processGO:00442653800.939
post embryonic developmentGO:000979120.933
Worm
ubiquitin dependent protein catabolic processGO:00065112060.895
modification dependent protein catabolic processGO:00199412090.845
cellular protein catabolic processGO:00442572610.731
cytoplasmic transportGO:00164823790.547
mitotic cell cycleGO:00002783260.488
mitotic cell cycle processGO:19030472860.476
positive regulation of cell deathGO:00109422630.471
Worm
determination of adult lifespanGO:000834020.459
regulation of proteolysisGO:00301622930.454
Fly
cellular response to dna damage stimulusGO:00069743790.424
proteolysis involved in cellular protein catabolic processGO:00516032440.422
proteasomal protein catabolic processGO:00104981760.422
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.420
multicellular organismal agingGO:001025930.413
intracellular protein transportGO:00068862700.413
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434710.396
neurogenesisGO:00220081690.369
Fly
positive regulation of catabolic processGO:00098963100.329
ncrna metabolic processGO:00346601080.326
immune system developmentGO:00025201950.316
regulation of mitotic cell cycleGO:00073461890.302
positive regulation of protein catabolic processGO:0045732750.293
myeloid cell differentiationGO:00300991170.290
dna integrity checkpointGO:0031570710.275
positive regulation of proteolysisGO:00458621420.239
regulation of proteasomal protein catabolic processGO:0061136870.236
modification dependent macromolecule catabolic processGO:00436322120.220
establishment of protein localization to organelleGO:00725941720.215
purine ribonucleoside triphosphate catabolic processGO:00092073910.206
vesicle mediated transportGO:00161923710.199
negative regulation of programmed cell deathGO:00430693210.186
cell cycle phase transitionGO:00447701730.184
hematopoietic or lymphoid organ developmentGO:00485341860.181
cell cycle checkpointGO:00000751170.175
embryo developmentGO:00097901230.165
Worm
hemopoiesisGO:00300971800.154
regulation of proteolysis involved in cellular protein catabolic processGO:1903050910.153
regulation of cell cycle processGO:00105642660.150
regulation of protein catabolic processGO:00421761550.147
regulation of cellular response to stressGO:00801352440.147
regulation of cell cycleGO:00517263930.144
positive regulation of protein modification by small protein conjugation or removalGO:1903322610.144
dna repairGO:00062811980.141
positive regulation of apoptotic processGO:00430652460.135
Worm
positive regulation of protein ubiquitinationGO:0031398530.132
regulation of cell cycle phase transitionGO:19019871260.130
regulation of mitotic cell cycle phase transitionGO:19019901180.122
embryo development ending in birth or egg hatchingGO:0009792340.120
Worm
endocytosisGO:00068971590.118
positive regulation of hydrolase activityGO:00513453310.107
sex differentiationGO:0007548450.105
Worm
protein targetingGO:00066051870.104
apoptotic signaling pathwayGO:00971902680.104
regulation of protein ubiquitinationGO:0031396950.099
Fly
regulation of protein modification by small protein conjugation or removalGO:19033201070.099
Fly
positive regulation of programmed cell deathGO:00430682490.093
Worm
negative regulation of cell cycle phase transitionGO:1901988890.093
negative regulation of cell deathGO:00605483450.092
positive regulation of nucleotide metabolic processGO:00459812300.092
female gamete generationGO:000729220.092
positive regulation of proteasomal protein catabolic processGO:1901800350.090
protein catabolic processGO:00301633250.089
reproductionGO:0000003630.088
Worm
microtubule based processGO:00070172100.088
positive regulation of cellular catabolic processGO:00313312840.088
mapk cascadeGO:00001652880.086
reactive oxygen species metabolic processGO:0072593750.085
protein maturationGO:00516042330.083
regulation of growthGO:00400081650.082
immune responseGO:00069553070.082
positive regulation of purine nucleotide catabolic processGO:00331231850.081
chemical homeostasisGO:00488783060.080
dna damage checkpointGO:0000077680.080
signal transduction by phosphorylationGO:00230142970.078
mitotic cell cycle checkpointGO:0007093680.077
cell cell signaling involved in cell fate commitmentGO:004516850.077
negative regulation of mitotic cell cycleGO:00459301020.075
regulation of cellular protein catabolic processGO:1903362960.070
cell developmentGO:00484683280.067
Fly
protein localization to organelleGO:00333652800.066
negative regulation of apoptotic processGO:00430663160.060
regulation of apoptotic signaling pathwayGO:20012331750.058
innate immune responseGO:00450871780.057
mitotic cell cycle phase transitionGO:00447721620.057
locomotory behaviorGO:000762610.057
purine containing compound catabolic processGO:00725234110.056
purine nucleoside triphosphate catabolic processGO:00091463920.055
cell divisionGO:00513011680.055
gtp metabolic processGO:00460392390.054
intrinsic apoptotic signaling pathwayGO:00971931270.053
nucleoside phosphate catabolic processGO:19012924120.053
reproductive structure developmentGO:0048608550.052
Worm
nucleoside catabolic processGO:00091644080.051
positive regulation of apoptotic signaling pathwayGO:2001235700.049
chromosome segregationGO:00070591140.048
regulation of nucleoside metabolic processGO:00091182090.048
regulation of sequence specific dna binding transcription factor activityGO:00510902110.048
enzyme linked receptor protein signaling pathwayGO:00071673030.046
cellular response to oxygen containing compoundGO:19017012760.045
negative regulation of catalytic activityGO:00430863350.044
receptor mediated endocytosisGO:0006898840.042
regulation of gtp catabolic processGO:00331241800.042
mitotic dna integrity checkpointGO:0044774300.041
cytokinesisGO:0000910960.041
response to cytokineGO:00340972320.040
multicellular organism reproductionGO:0032504420.038
maintenance of locationGO:00512351120.038
autophagyGO:0006914880.038
adult locomotory behaviorGO:000834410.037
organophosphate catabolic processGO:00464344300.037
ribonucleoside catabolic processGO:00424544060.036
cullin deneddylationGO:001038890.035
growthGO:00400072020.035
regulation of reactive oxygen species metabolic processGO:2000377410.034
purine ribonucleoside metabolic processGO:00461284370.034
oogenesisGO:004847720.034
guanosine containing compound catabolic processGO:19010692390.033
g2 dna damage checkpointGO:0031572260.033
nucleoside triphosphate metabolic processGO:00091414220.033
negative regulation of mitotic cell cycle phase transitionGO:1901991850.033
response to light stimulusGO:0009416870.032
agingGO:0007568660.032
regulation of peptidase activityGO:00525471800.032
regulation of mitosisGO:0007088630.032
oocyte developmentGO:004859910.031
positive regulation of nucleotide catabolic processGO:00308131850.031
cellular component morphogenesisGO:00329893140.030
Fly
regulation of transferase activityGO:00513383550.029
Fly
nervous system developmentGO:00073992930.029
Fly
purine nucleoside triphosphate metabolic processGO:00091444120.028
regulation of protein processingGO:00706131500.028
cellular macromolecular complex assemblyGO:00346223240.027
regulation of mapk cascadeGO:00434082620.027
purine ribonucleoside triphosphate metabolic processGO:00092054110.027
lipid localizationGO:00108761060.026
regulation of intrinsic apoptotic signaling pathwayGO:2001242720.026
response to abiotic stimulusGO:00096283360.026
multicellular organismal reproductive processGO:0048609400.026
negative regulation of cell cycle processGO:00109481210.026
regulation of purine nucleotide catabolic processGO:00331212050.025
blastoderm segmentationGO:000735020.025
meiotic chromosome segregationGO:004513240.025
oocyte differentiationGO:000999420.025
positive regulation of protein phosphorylationGO:00019343130.025
regulation of endopeptidase activityGO:00525481700.025
cellular response to endogenous stimulusGO:00714953360.024
ribonucleoside triphosphate catabolic processGO:00092033910.024
response to organonitrogen compoundGO:00102431560.023
cell projection morphogenesisGO:00488581290.023
Fly
positive regulation of purine nucleotide metabolic processGO:19005442270.023
regulation of purine nucleotide metabolic processGO:19005422640.023
ribosome biogenesisGO:0042254480.022
regulation of response to dna damage stimulusGO:2001020940.022
negative regulation of proteolysisGO:00458611320.021
positive regulation of nucleoside metabolic processGO:00459791860.021
nucleoside monophosphate metabolic processGO:00091231910.021
tripartite regional subdivisionGO:000735120.020
positive regulation of transportGO:00510503360.020
response to metal ionGO:0010038840.020
glycosyl compound catabolic processGO:19016584130.020
positive regulation of sequence specific dna binding transcription factor activityGO:00510911310.020
regulation of immune responseGO:00507762010.020
segmentationGO:003528240.020
protein polyubiquitinationGO:00002091100.020
negative regulation of cellular protein metabolic processGO:00322693530.019
organelle fissionGO:00482851490.019
guanosine containing compound metabolic processGO:19010682440.019
generation of neuronsGO:00486991520.019
Fly
protein localization to nucleusGO:00345041360.018
posttranscriptional regulation of gene expressionGO:00106082130.018
Fly
negative regulation of cellular catabolic processGO:0031330830.018
mitotic dna damage checkpointGO:0044773280.018
regulation of nucleotide metabolic processGO:00061402690.018
reproductive processGO:00224141060.017
Worm
response to other organismGO:00517072610.017
developmental process involved in reproductionGO:0003006660.017
Worm
purine ribonucleoside catabolic processGO:00461303980.017
anterior posterior axis specificationGO:000994820.017
regulation of protein localizationGO:00328802960.017
development of primary sexual characteristicsGO:0045137350.017
Worm
ncrna processingGO:0034470830.017
microtubule cytoskeleton organizationGO:00002261760.016
purine nucleotide catabolic processGO:00061954050.016
positive regulation of cellular amino acid metabolic processGO:004576430.016
cellular amine metabolic processGO:0044106410.016
negative regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043154460.016
negative regulation of protein maturationGO:19033181420.016
methylationGO:00322591060.016
protein deneddylationGO:0000338100.015
response to external biotic stimulusGO:00432072610.015
cell type specific apoptotic processGO:00972851250.015
single organism reproductive processGO:0044702980.015
Worm
cellular response to nitrogen compoundGO:19016991440.015
establishment of nucleus localizationGO:004002310.015
regulation of protein maturationGO:19033171500.015
cell agingGO:0007569520.015
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.015
mitotic nuclear divisionGO:00070671190.015
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.015
regulation of response to external stimulusGO:00321012220.015
rrna metabolic processGO:0016072400.015
regulation of stress activated protein kinase signaling cascadeGO:0070302850.015
protein importGO:00170381300.014
negative regulation of protein processingGO:00109551420.014
mitochondrion organizationGO:00070051560.014
purine ribonucleotide catabolic processGO:00091544040.014
regulation of membrane potentialGO:0042391950.014
negative regulation of cell cycleGO:00457861930.014
regulation of cellular component biogenesisGO:00440872810.014
regulation of gtpase activityGO:00430871800.014
negative regulation of hydrolase activityGO:00513461820.014
regulation of protein kinase activityGO:00458592890.014
regulation of establishment of protein localizationGO:00702012420.014
positive regulation of gtp catabolic processGO:00331261660.014
cellular chemical homeostasisGO:00550821800.014
multi organism reproductive processGO:0044703540.014
positive regulation of proteolysis involved in cellular protein catabolic processGO:1903052350.014
cellular ketone metabolic processGO:0042180800.013
purine nucleoside catabolic processGO:00061523980.013
regulation of kinase activityGO:00435493140.013
ribosomal large subunit biogenesisGO:0042273100.013
negative regulation of phosphate metabolic processGO:00459362670.013
regulation of peptidyl serine phosphorylationGO:0033135500.013
mitotic g2 m transition checkpointGO:004481890.013
defense response to other organismGO:00985421290.013
negative regulation of cell proliferationGO:00082852280.013
gtp catabolic processGO:00061842370.013
protein monoubiquitinationGO:0006513390.013
regulation of map kinase activityGO:00434051080.012
positive regulation of cellular amine metabolic processGO:003324070.012
regulation of cellular amine metabolic processGO:0033238110.012
anterior posterior axis specification embryoGO:000859520.012
cellular response to oxidative stressGO:0034599850.012
negative regulation of cysteine type endopeptidase activityGO:2000117480.012
cellular response to hydrogen peroxideGO:0070301370.012
positive regulation of cellular component organizationGO:00511303760.012
chromosome separationGO:0051304230.012
regulation of stress activated mapk cascadeGO:0032872840.012
response to biotic stimulusGO:00096072760.012
regulation of cellular component movementGO:00512703340.012
positive regulation of intrinsic apoptotic signaling pathwayGO:2001244280.012
mitotic g2 dna damage checkpointGO:000709570.012
mitotic cytokinesisGO:0000281190.012
negative regulation of multicellular organismal processGO:00512413170.012
organelle localizationGO:0051640840.012
ribonucleotide catabolic processGO:00092614050.011
regulation of ubiquitin protein transferase activityGO:0051438280.011
Fly
positive regulation of spindle checkpointGO:009023270.011
negative regulation of phosphorus metabolic processGO:00105632670.011
response to acid chemicalGO:0001101660.011
cytokine productionGO:00018162470.011
positive regulation of gtpase activityGO:00435471660.011
positive regulation of phosphorylationGO:00423273940.011
behaviorGO:00076101120.011
ras protein signal transductionGO:0007265730.011
cytosolic calcium ion homeostasisGO:0051480890.011
amine metabolic processGO:0009308440.011
positive regulation of nf kappab transcription factor activityGO:0051092810.011
regulation of nucleotide catabolic processGO:00308112050.011
negative regulation of transportGO:00510511760.011
positive regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032436300.010
positive regulation of reactive oxygen species metabolic processGO:2000379240.010
cell growthGO:00160491600.010
cellular response to acid chemicalGO:0071229440.010
ribonucleoside triphosphate metabolic processGO:00091994120.010
response to nitrogen compoundGO:19016981840.010
stress activated protein kinase signaling cascadeGO:0031098940.010

NEDD8 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
immune system diseaseDOID:29141550.084
bone marrow diseaseDOID:4961310.084
hematopoietic system diseaseDOID:741000.084
anemiaDOID:2355550.019
eye and adnexa diseaseDOID:14921500.017
nervous system diseaseDOID:8634310.017
sensory system diseaseDOID:00501552030.017
congenital hypoplastic anemiaDOID:1342260.011
aplastic anemiaDOID:12449300.011
endocrine gland cancerDOID:170260.011
cancerDOID:1621670.011
organ system cancerDOID:00506861640.011
disease of cellular proliferationDOID:145661740.011