Homo sapiens

65 known processes

TAP1

transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)

(Aliases: ABC17,TAP1*0102N,TAP1N,RING4,APT1,ABCB2,FLJ26666,D6S114E,PSF1,FLJ41500)

TAP1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
antigen processing and presentation via mhc class ibGO:000247531.000
Human
regulation of natural killer cell mediated cytotoxicityGO:0042269161.000
Rat
antigen processing and presentation of peptide antigen via mhc class iGO:000247460.999
antigen processing and presentation of endogenous peptide antigen via mhc class ibGO:000247620.999
Human
negative regulation of leukocyte mediated immunityGO:0002704140.997
Rat
immune response inhibiting cell surface receptor signaling pathwayGO:000276740.993
natural killer cell mediated cytotoxicityGO:0042267230.991
Rat
transport of virusGO:0046794140.991
detection of chemical stimulusGO:0009593550.987
lymphocyte mediated immunityGO:0002449480.986
Rat
negative regulation of leukocyte mediated cytotoxicityGO:000191150.984
Rat
viral life cycleGO:00190581320.982
regulation by virus of viral protein levels in host cellGO:004671940.981
viral processGO:00160321460.979
negative regulation of lymphocyte mediated immunityGO:0002707120.970
Rat
multi organism cellular processGO:00447641560.967
immune effector processGO:00022521590.966
Rat
regulation of regulatory t cell differentiationGO:004558940.965
leukocyte mediated cytotoxicityGO:0001909270.962
Rat
symbiosis encompassing mutualism through parasitismGO:00444031560.962
t cell mediated immunityGO:0002456250.959
antigen processing and presentation of endogenous peptide antigen via mhc class iGO:001988550.959
intracellular transport of virusGO:0075733140.947
adaptive immune responseGO:0002250490.943
positive regulation of leukocyte mediated immunityGO:0002705240.942
defense responseGO:00069523150.940
Mouse Rat
positive regulation of leukocyte mediated cytotoxicityGO:0001912160.939
leukocyte mediated immunityGO:0002443590.936
Rat
regulation of adaptive immune responseGO:0002819330.936
antigen processing and presentation of peptide antigen via mhc class ibGO:000242820.932
Human
regulation of immune responseGO:00507762010.931
Rat
multi organism transportGO:0044766140.925
positive regulation of cell killingGO:0031343190.906
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002824190.893
positive regulation of t cell mediated immunityGO:0002711120.892
regulation of leukocyte mediated immunityGO:0002703380.892
Rat
antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathwayGO:000248430.887
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002460400.877
response to other organismGO:00517072610.870
negative regulation of defense responseGO:0031348470.856
Rat
interaction with hostGO:0051701420.850
multi organism localizationGO:1902579140.846
positive regulation of lymphocyte mediated immunityGO:0002708230.846
cytoplasmic transportGO:00164823790.839
response to external biotic stimulusGO:00432072610.829
regulation of t cell mediated immunityGO:0002709180.827
sensory perception of tasteGO:0050909360.817
response to bacteriumGO:00096171440.815
positive regulation of regulatory t cell differentiationGO:004559130.808
positive regulation of immune effector processGO:0002699400.804
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822290.800
immune responseGO:00069553070.795
Rat
regulation of symbiosis encompassing mutualism through parasitismGO:00439031090.788
regulation of defense responseGO:00313471540.773
Rat
antigen processing and presentationGO:0019882330.749
positive regulation of immune system processGO:00026842830.745
response to biotic stimulusGO:00096072760.706
regulation of viral processGO:00507921030.688
regulation of immune effector processGO:0002697910.682
Rat
regulation of innate immune responseGO:0045088970.679
Rat
immune response inhibiting signal transductionGO:000276540.668
regulation of cell killingGO:0031341220.649
Rat
regulation of t cell mediated cytotoxicityGO:000191480.632
antigen processing and presentation of endogenous antigenGO:001988370.629
sensory perception of chemical stimulusGO:0007606380.626
regulation of lymphocyte mediated immunityGO:0002706330.608
Rat
antigen processing and presentation of endogenous peptide antigenGO:000248360.608
detection of external biotic stimulusGO:0098581190.605
regulation of multi organism processGO:00439001570.601
positive regulation of cytokine productionGO:00018191670.580
positive regulation of developmental processGO:00510943140.573
intracellular protein transportGO:00068862700.555
detection of chemical stimulus involved in sensory perceptionGO:0050907330.547
positive regulation of adaptive immune responseGO:0002821210.534
immune response regulating signaling pathwayGO:0002764970.525
t cell proliferationGO:0042098450.479
regulation of interferon gamma productionGO:0032649360.472
multi organism intracellular transportGO:1902583140.448
natural killer cell mediated immunityGO:0002228230.446
Rat
innate immune responseGO:00450871780.414
Rat
interspecies interaction between organismsGO:00444191560.395
sensory perception of bitter tasteGO:0050913280.390
mononuclear cell proliferationGO:0032943710.385
chemical homeostasisGO:00488783060.370
regulation of interleukin 12 productionGO:0032655150.341
positive regulation of natural killer cell mediated immunityGO:0002717120.335
positive regulation of leukocyte activationGO:0002696800.327
lymphocyte proliferationGO:0046651700.308
antigen processing and presentation of peptide antigenGO:0048002180.307
positive regulation of antigen processing and presentationGO:000257910.302
t cell mediated cytotoxicityGO:000191390.302
detection of biotic stimulusGO:0009595210.298
regulation of leukocyte mediated cytotoxicityGO:0001910190.293
Rat
regulation of leukocyte activationGO:00026941150.291
amide transportGO:0042886760.289
positive regulation of t cell mediated cytotoxicityGO:000191670.287
import into cellGO:009865720.273
cytokine productionGO:00018162470.272
negative regulation of immune effector processGO:0002698380.270
Rat
positive regulation of innate immune responseGO:0045089790.259
interferon gamma productionGO:0032609390.251
positive regulation of defense responseGO:0031349870.251
positive regulation of immune responseGO:00507781590.251
negative regulation of t cell proliferationGO:004213080.243
regulation of lymphocyte proliferationGO:0050670640.241
multicellular organismal homeostasisGO:0048871670.240
regulation of t cell differentiationGO:0045580190.231
peptide transportGO:0015833740.230
lymphocyte activationGO:00466491330.221
t cell tolerance inductionGO:000251740.221
response to molecule of bacterial originGO:0002237820.214
positive regulation of interferon gamma productionGO:0032729260.204
regulation of lymphocyte activationGO:00512491030.203
immune response regulating cell surface receptor signaling pathwayGO:0002768510.200
t cell activationGO:0042110990.197
cell activationGO:00017752130.191
regulation of t cell tolerance inductionGO:000266440.191
regulation of cytokine productionGO:00018172320.188
negative regulation of immune system processGO:00026831360.181
Rat
positive regulation of cell differentiationGO:00455972110.171
detection of stimulus involved in sensory perceptionGO:0050906430.163
negative regulation of developmental processGO:00510932470.162
antigen processing and presentation of exogenous antigenGO:001988440.160
positive regulation of i kappab kinase nf kappab signalingGO:00431231320.159
detection of stimulusGO:0051606850.159
iron ion import into cellGO:009745920.158
hematopoietic or lymphoid organ developmentGO:00485341860.156
regulation of leukocyte proliferationGO:0070663670.152
regulation of cell differentiationGO:00455953930.151
cell adhesionGO:00071553250.148
intracellular transport of viral protein in host cellGO:001906040.143
regulation of t cell activationGO:0050863770.143
regulation of mononuclear cell proliferationGO:0032944650.142
regulation of leukocyte differentiationGO:1902105610.129
negative regulation of leukocyte activationGO:0002695260.123
regulation of t cell proliferationGO:0042129420.118
type i interferon signaling pathwayGO:0060337110.117
negative regulation of multicellular organismal processGO:00512413170.116
positive regulation of lymphocyte differentiationGO:0045621130.114
immune response activating signal transductionGO:0002757900.113
post embryonic developmentGO:000979120.113
cell killingGO:0001906340.110
Rat
negative regulation of viral processGO:0048525660.108
regulation of viral entry into host cellGO:0046596170.102
extracellular transportGO:000685840.102
leukocyte differentiationGO:0002521980.101
positive regulation of cell activationGO:0050867810.095
positive regulation of lymphocyte activationGO:0051251730.094
regulation of lymphocyte differentiationGO:0045619220.092
protection from natural killer cell mediated cytotoxicityGO:004227030.092
Rat
regulation of cell activationGO:00508651250.092
positive regulation of interleukin 12 productionGO:003273580.089
leukocyte activationGO:00453211640.080
activation of immune responseGO:00022531140.079
dendritic cell differentiationGO:0097028130.079
negative regulation of cell proliferationGO:00082852280.079
regulation of apoptotic signaling pathwayGO:20012331750.078
positive regulation of interleukin 13 productionGO:003273640.077
defense response to other organismGO:00985421290.075
lymphocyte differentiationGO:0030098350.075
cd8 positive alpha beta t cell activationGO:003603730.071
apoptotic signaling pathwayGO:00971902680.071
cation transportGO:00068123310.071
system processGO:00030083490.071
antigen processing and presentation of exogenous peptide antigenGO:000247840.068
negative regulation of cell activationGO:0050866330.067
nuclear exportGO:0051168690.065
regulation of natural killer cell mediated immunityGO:0002715160.064
Rat
response to abiotic stimulusGO:00096283360.063
immune system developmentGO:00025201950.063
t cell differentiationGO:0030217290.062
cellular protein complex assemblyGO:00436231880.062
positive regulation of programmed cell deathGO:00430682490.062
regulation of cell cycleGO:00517263930.061
response to peptidoglycanGO:003249430.060
proteolysis involved in cellular protein catabolic processGO:00516032440.059
regulation of transferase activityGO:00513383550.059
purine containing compound catabolic processGO:00725234110.058
Human Rat
cellular response to cytokine stimulusGO:00713451810.057
positive regulation of apoptotic processGO:00430652460.056
antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathway tap independentGO:000248630.056
mitotic cell cycle processGO:19030472860.054
positive regulation of leukocyte differentiationGO:1902107370.053
positive regulation of interleukin 4 biosynthetic processGO:004540410.053
nucleoside phosphate biosynthetic processGO:19012931090.052
negative regulation of cell cycleGO:00457861930.048
cellular response to dna damage stimulusGO:00069743790.047
negative regulation of viral genome replicationGO:0045071350.046
regulation of proteolysisGO:00301622930.046
tissue homeostasisGO:0001894630.046
negative regulation of phosphate metabolic processGO:00459362670.046
detection of chemical stimulus involved in sensory perception of tasteGO:0050912310.046
positive regulation of memory t cell activationGO:200056810.044
extrinsic apoptotic signaling pathwayGO:00971911190.043
activation of innate immune responseGO:0002218550.042
negative regulation of multi organism processGO:0043901920.042
positive regulation of mhc class i biosynthetic processGO:004534540.041
natural killer cell differentiationGO:000177920.041
positive regulation of production of molecular mediator of immune responseGO:0002702110.040
anatomical structure homeostasisGO:00602491000.040
cellular response to external stimulusGO:00714961110.040
positive regulation of t cell activationGO:0050870540.039
negative regulation of dendritic cell differentiationGO:200119920.038
biological adhesionGO:00226103310.038
cellular response to interferon gammaGO:0071346240.038
detection of other organismGO:0098543130.038
cellular response to lipidGO:00713961270.034
positive regulation of cell deathGO:00109422630.034
cellular macromolecule catabolic processGO:00442653800.034
cell cycle arrestGO:0007050710.034
regulation of transmembrane transportGO:00347621390.034
inorganic ion import into cellGO:009958720.033
pattern recognition receptor signaling pathwayGO:0002221480.032
regulation of dendritic cell differentiationGO:200119830.032
regulation of antigen processing and presentation of peptide antigenGO:000258340.031
leukocyte proliferationGO:0070661740.030
response to virusGO:00096151260.030
mitotic spindle elongationGO:000002240.029
negative regulation of phosphorus metabolic processGO:00105632670.029
metal ion transportGO:00300012720.029
regulation of cellular protein catabolic processGO:1903362960.029
negative regulation of apoptotic processGO:00430663160.028
cellular protein catabolic processGO:00442572610.028
negative regulation of protein metabolic processGO:00512483910.028
defense response to virusGO:0051607710.028
negative regulation of lymphocyte activationGO:0051250240.028
response to mechanical stimulusGO:0009612510.027
spindle elongationGO:005123140.027
negative regulation of mononuclear cell proliferationGO:0032945150.027
purine ribonucleoside triphosphate metabolic processGO:00092054110.027
Human Rat
iron ion transportGO:0006826120.027
modification dependent protein catabolic processGO:00199412090.027
nucleotide catabolic processGO:00091664080.027
Human Rat
hemopoiesisGO:00300971800.026
regulation of cell migrationGO:00303342890.026
microtubule organizing center organizationGO:0031023620.026
interleukin 13 productionGO:003261670.026
negative regulation of apoptotic signaling pathwayGO:2001234970.025
sensory perceptionGO:00076001030.025
centrosome organizationGO:0051297580.025
protein export from nucleusGO:0006611290.025
regulation of proteolysis involved in cellular protein catabolic processGO:1903050910.025
purine nucleotide catabolic processGO:00061954050.024
Human Rat
entry into host cellGO:0030260250.023
intracellular protein transport in other organism involved in symbiotic interactionGO:005170840.023
negative regulation of immune responseGO:0050777400.023
Rat
regulation of interleukin 4 biosynthetic processGO:004540220.023
regulation of tolerance inductionGO:000264340.022
regenerationGO:003109940.022
posttranscriptional regulation of gene expressionGO:00106082130.022
positive regulation of cytokine biosynthetic processGO:0042108250.022
regulation of viral transcriptionGO:0046782340.022
regulation of natural killer cell differentiationGO:003282320.022
positive regulation of apoptotic signaling pathwayGO:2001235700.022
negative regulation of cell motilityGO:20001461040.021
protein catabolic processGO:00301633250.021
microtubule cytoskeleton organizationGO:00002261760.021
regulation of type i interferon productionGO:0032479260.021
negative regulation of natural killer cell mediated immunityGO:000271650.021
Rat
mitotic cell cycleGO:00002783260.021
t cell differentiation in thymusGO:003307740.021
positive regulation of cellular component biogenesisGO:00440891580.021
purine nucleoside triphosphate metabolic processGO:00091444120.021
Human Rat
multi organism metabolic processGO:0044033410.021
positive regulation of interferon beta productionGO:0032728170.021
regulation of protein modification by small protein conjugation or removalGO:19033201070.020
regulation of extrinsic apoptotic signaling pathwayGO:2001236850.020
innate immune response activating signal transductionGO:0002758480.020
protein localization to organelleGO:00333652800.019
regulation of cd8 positive alpha beta t cell proliferationGO:200056410.019
guanosine containing compound catabolic processGO:19010692390.019
interleukin 4 biosynthetic processGO:004209720.019
nucleocytoplasmic transportGO:00069131760.019
determination of adult lifespanGO:000834020.018
negative regulation of interleukin 2 secretionGO:190004120.018
regulation of protein localizationGO:00328802960.018
positive regulation of proteolysisGO:00458621420.018
microtubule based processGO:00070172100.018
negative regulation of extrinsic apoptotic signaling pathwayGO:2001237520.018
interleukin 2 productionGO:0032623200.018
negative regulation of cell differentiationGO:00455961710.017
purine ribonucleotide catabolic processGO:00091544040.017
Human Rat
negative regulation of cell deathGO:00605483450.017
regulation of purine nucleotide metabolic processGO:19005422640.017
regulation of cell cycle phase transitionGO:19019871260.017
nucleoside phosphate catabolic processGO:19012924120.017
Human Rat
regulation of kinase activityGO:00435493140.017
memory t cell activationGO:003570910.017
ribonucleoside triphosphate catabolic processGO:00092033910.017
Human Rat
negative regulation of leukocyte differentiationGO:1902106240.016
protein refoldingGO:0042026140.016
positive regulation of cellular catabolic processGO:00313312840.016
regulation of cytokine biosynthetic processGO:0042035350.016
regulation of cytoskeleton organizationGO:00514931770.016
regulation of antigen processing and presentationGO:000257760.016
positive regulation of tolerance inductionGO:000264520.015
regulation of protein catabolic processGO:00421761550.015
negative regulation of natural killer cell mediated cytotoxicityGO:004595350.015
Rat
protein oligomerizationGO:00512591730.015
purine nucleoside catabolic processGO:00061523980.015
Human Rat
rna catabolic processGO:0006401710.015
regulation of cellular component movementGO:00512703340.015
mitotic cell cycle phase transitionGO:00447721620.015
response to type i interferonGO:0034340140.015
negative regulation of catalytic activityGO:00430863350.014
transition metal ion transportGO:0000041230.014
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.014
negative regulation of phosphorylationGO:00423261740.014
mitotic spindle organizationGO:0007052270.014
modification dependent macromolecule catabolic processGO:00436322120.014
cellular macromolecular complex assemblyGO:00346223240.014
nucleoside triphosphate metabolic processGO:00091414220.013
Human Rat
regulation of response to cytokine stimulusGO:0060759460.013
negative regulation of kinase activityGO:00336731060.013
entry into hostGO:0044409250.013
regulation of purine nucleotide catabolic processGO:00331212050.013
regulatory t cell differentiationGO:004506650.013
response to muramyl dipeptideGO:003249540.013
response to interferon gammaGO:0034341390.013
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.013
mapk cascadeGO:00001652880.013
detection of peptidoglycanGO:003249910.012
positive regulation of interleukin 2 productionGO:0032743110.012
positive regulation of protein complex assemblyGO:0031334860.012
osteoblast differentiationGO:0001649920.012
positive regulation of secretionGO:00510471160.012
negative regulation of leukocyte proliferationGO:0070664160.012
regulation of anatomical structure morphogenesisGO:00226032860.012
regulation of cysteine type endopeptidase activityGO:20001161270.012
regulation of endopeptidase activityGO:00525481700.012
regulation of intracellular transportGO:00323861950.012
negative regulation of transferase activityGO:00513481240.012
ubiquitin dependent protein catabolic processGO:00065112060.012
negative regulation of cellular protein metabolic processGO:00322693530.012
alpha beta t cell differentiationGO:004663270.012
negative regulation of t cell activationGO:0050868180.011
regulation of viral genome replicationGO:0045069480.011
negative regulation of viral release from host cellGO:1902187120.011
nucleoside triphosphate catabolic processGO:00091433940.011
Human Rat
negative regulation of protein modification processGO:00314002000.011
cytokine biosynthetic processGO:0042089370.011
glycosyl compound catabolic processGO:19016584130.011
Human Rat
negative regulation of innate immune responseGO:0045824180.011
Rat
single organism cellular localizationGO:19025803320.011
positive regulation of synaptic transmissionGO:005080640.011
neurogenesisGO:00220081690.011
extrinsic apoptotic signaling pathway in absence of ligandGO:0097192220.011
proteasomal ubiquitin independent protein catabolic processGO:001049930.011
interleukin 12 productionGO:0032615150.010
negative regulation of mitotic cell cycleGO:00459301020.010
regulation of nucleoside metabolic processGO:00091182090.010
negative regulation of cell cycle g1 s phase transitionGO:1902807290.010
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.010
gtp catabolic processGO:00061842370.010
positive regulation of interleukin 4 productionGO:003275330.010

TAP1 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
primary immunodeficiency diseaseDOID:612360.984
combined t cell and b cell immunodeficiencyDOID:628120.984
severe combined immunodeficiencyDOID:627100.984
immune system diseaseDOID:29141550.984
organ system cancerDOID:00506861640.045
disease of cellular proliferationDOID:145661740.045
cancerDOID:1621670.045
disease by infectious agentDOID:0050117340.028
viral infectious diseaseDOID:934130.028
musculoskeletal system diseaseDOID:172230.022
human immunodeficiency virus infectious diseaseDOID:526130.011
acquired immunodeficiency syndromeDOID:635130.011
mhc class i deficiencyDOID:006000930.001