Homo sapiens

27 known processes

TWIST2

twist homolog 2 (Drosophila)

(Aliases: DERMO1,bHLHa39,MGC117334)

TWIST2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of cardioblast differentiationGO:005189040.436
tube developmentGO:00352951250.434
segmentationGO:003528240.384
negative regulation of cell fate commitmentGO:001045430.353
regulation of locomotionGO:00400123290.336
negative regulation of cell fate specificationGO:000999630.317
regulation of stem cell differentiationGO:2000736560.299
anatomical structure formation involved in morphogenesisGO:00486462840.240
positive regulation of developmental processGO:00510943140.236
tube morphogenesisGO:0035239950.234
regulation of anatomical structure morphogenesisGO:00226032860.226
digestive system developmentGO:0055123750.223
negative regulation of cardioblast differentiationGO:005189220.213
digestive tract morphogenesisGO:0048546560.200
positive regulation of cell proliferationGO:00082843010.200
cellular ketone metabolic processGO:0042180800.199
digestive tract developmentGO:0048565750.192
regulation of cellular component movementGO:00512703340.190
embryonic morphogenesisGO:0048598850.181
stem cell differentiationGO:0048863930.172
blastoderm segmentationGO:000735020.168
organ morphogenesisGO:00098871470.166
regulation of cell motilityGO:20001452990.162
ameboidal type cell migrationGO:00016671350.161
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.160
anterior posterior axis specificationGO:000994820.160
circulatory system developmentGO:00723592620.154
gastrulationGO:0007369510.152
enzyme linked receptor protein signaling pathwayGO:00071673030.151
vasculature developmentGO:00019441810.146
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.145
regulation of cell migrationGO:00303342890.144
negative regulation of developmental processGO:00510932470.143
regulation of endothelial cell migrationGO:0010594670.142
positive regulation of endothelial cell migrationGO:0010595390.141
negative regulation of stem cell differentiationGO:2000737220.140
negative regulation of cell differentiationGO:00455961710.134
anterior posterior axis specification embryoGO:000859520.125
response to oxygen containing compoundGO:19017003690.122
positive regulation of locomotionGO:00400171860.118
negative regulation of programmed cell deathGO:00430693210.117
cardiac cell fate specificationGO:006091210.117
regulation of cell differentiationGO:00455953930.111
negative regulation of multicellular organismal processGO:00512413170.107
positive regulation of cell migrationGO:00303351720.106
positive regulation of cell motilityGO:20001471770.104
regulation of cardiac cell fate specificationGO:200004310.102
blood vessel morphogenesisGO:00485141620.099
regulation of epithelial cell migrationGO:0010632930.099
positive regulation of cellular component movementGO:00512721810.099
cardiovascular system developmentGO:00723582620.097
tripartite regional subdivisionGO:000735120.090
regulation of angiogenesisGO:0045765920.090
regulation of cellular ketone metabolic processGO:0010565500.089
blood vessel developmentGO:00015681720.088
positive regulation of epithelial cell migrationGO:0010634550.088
regulation of cell developmentGO:00602841610.085
cellular component morphogenesisGO:00329893140.085
positive regulation of cellular component organizationGO:00511303760.083
forelimb morphogenesisGO:003513640.082
biological adhesionGO:00226103310.081
muscle structure developmentGO:0061061980.080
response to abiotic stimulusGO:00096283360.080
angiogenesisGO:00015251470.079
positive regulation of erythrocyte differentiationGO:0045648110.077
lipid metabolic processGO:00066293810.074
fatty acid metabolic processGO:00066311150.073
positive regulation of cellular amino acid metabolic processGO:004576430.070
hematopoietic or lymphoid organ developmentGO:00485341860.070
negative regulation of cell deathGO:00605483450.068
apoptotic signaling pathwayGO:00971902680.066
tissue migrationGO:00901301190.064
positive regulation of cell differentiationGO:00455972110.064
cellular amino acid metabolic processGO:00065201160.063
epithelial cell migrationGO:00106311190.063
nervous system developmentGO:00073992930.063
cardioblast cell fate commitmentGO:004268410.062
mesenchyme developmentGO:0060485590.062
cell developmentGO:00484683280.062
cellular amine metabolic processGO:0044106410.062
regulation of cellular amine metabolic processGO:0033238110.061
vesicle mediated transportGO:00161923710.060
epithelium migrationGO:00901321190.059
single organismal cell cell adhesionGO:00163371480.059
wnt signaling pathwayGO:00160551560.059
epithelium developmentGO:00604292270.059
negative regulation of apoptotic processGO:00430663160.059
single organism cell adhesionGO:00986021790.058
tissue morphogenesisGO:0048729960.057
regulation of homeostatic processGO:00328441210.057
negative regulation of cell cycleGO:00457861930.056
cellular response to endogenous stimulusGO:00714953360.056
post embryonic developmentGO:000979120.055
negative regulation of apoptotic signaling pathwayGO:2001234970.054
regulation of vasculature developmentGO:1901342970.054
morphogenesis of embryonic epitheliumGO:001633140.054
secretionGO:00469032540.053
cell morphogenesis involved in differentiationGO:00009041440.053
secretion by cellGO:00329402260.053
regulation of cellular amino acid metabolic processGO:000652160.052
cardiac right ventricle morphogenesisGO:000321530.052
mesenchymal cell differentiationGO:0048762520.051
heart developmentGO:0007507950.051
canonical wnt signaling pathwayGO:00600701160.050
regulation of cytokine productionGO:00018172320.050
amine metabolic processGO:0009308440.050
negative regulation of protein metabolic processGO:00512483910.049
regulation of secretionGO:00510461940.047
regulation of wnt signaling pathwayGO:00301111230.047
regulation of cell cycleGO:00517263930.046
cell adhesionGO:00071553250.046
regulation of apoptotic signaling pathwayGO:20012331750.046
cardioblast cell fate specificationGO:004268510.045
cell morphogenesisGO:00009022960.045
chromatin organizationGO:00063253510.045
soft palate developmentGO:006002330.045
cardiocyte differentiationGO:0035051230.045
myeloid cell differentiationGO:00300991170.044
regulation of neurogenesisGO:0050767820.044
chromatin modificationGO:00165682980.043
cellular lipid metabolic processGO:00442553030.043
regulation of secretion by cellGO:19035301770.043
generation of neuronsGO:00486991520.043
cellular response to growth factor stimulusGO:00713631970.043
embryonic forelimb morphogenesisGO:003511540.042
regulation of myeloid cell differentiationGO:0045637810.042
neural crest cell developmentGO:001403230.042
positive regulation of immune system processGO:00026842830.042
gastrulation with mouth forming secondGO:000170210.042
system processGO:00030083490.041
extraocular skeletal muscle developmentGO:000207410.040
response to growth factorGO:00708482050.040
hindbrain developmentGO:003090230.040
regulation of hormone levelsGO:00108171250.039
regulation of cardioblast cell fate specificationGO:004268610.039
positive regulation of phosphorylationGO:00423273940.039
neurogenesisGO:00220081690.038
response to woundingGO:00096111680.038
regionalizationGO:0003002290.038
mitotic cell cycleGO:00002783260.038
lipid biosynthetic processGO:00086101770.037
cellular response to nitrogen compoundGO:19016991440.037
multicellular organismal agingGO:001025930.037
rho protein signal transductionGO:0007266260.037
small molecule biosynthetic processGO:00442831570.036
negative regulation of cell proliferationGO:00082852280.035
hemopoiesisGO:00300971800.035
mesoderm developmentGO:0007498140.035
cellular response to oxygen containing compoundGO:19017012760.035
negative regulation of transportGO:00510511760.035
positive regulation of transportGO:00510503360.035
regulation of proteolysisGO:00301622930.035
respiratory system developmentGO:0060541220.035
epithelial cell differentiationGO:00308551410.034
embryonic epithelial tube formationGO:000183840.034
alcohol metabolic processGO:00060661140.034
positive regulation of homeostatic processGO:0032846470.034
regulation of sequence specific dna binding transcription factor activityGO:00510902110.033
determination of adult lifespanGO:000834020.033
locomotory behaviorGO:000762610.033
female gamete generationGO:000729220.033
cranial nerve developmentGO:002154540.033
negative regulation of cellular amine metabolic processGO:003323930.033
monocarboxylic acid metabolic processGO:00327871850.033
cytoplasmic transportGO:00164823790.032
regulation of erythrocyte differentiationGO:0045646170.032
menstrual cycle phaseGO:002260120.032
histone modificationGO:00165702510.032
embryo developmentGO:00097901230.032
positive regulation of organelle organizationGO:00106381950.032
small gtpase mediated signal transductionGO:0007264780.032
regulation of response to external stimulusGO:00321012220.032
oogenesisGO:004847720.031
actin filament based processGO:00300292240.031
cell cell signalingGO:00072671550.031
negative regulation of cellular component organizationGO:00511292350.031
nitrogen compound transportGO:00717051910.031
defense responseGO:00069523150.031
positive regulation of cell deathGO:00109422630.030
formation of primary germ layerGO:0001704420.030
positive regulation of apoptotic processGO:00430652460.030
growthGO:00400072020.030
mesodermal cell fate commitmentGO:000171020.030
striated muscle cell differentiationGO:0051146430.030
embryonic camera type eye developmentGO:003107620.030
hindlimb morphogenesisGO:003513720.030
trachea developmentGO:006043810.029
pattern specification processGO:0007389430.029
regulation of cell cycle processGO:00105642660.029
regulation of protein transportGO:00512232130.029
response to organic cyclic compoundGO:00140702040.029
positive regulation of catabolic processGO:00098963100.029
single organism membrane organizationGO:00448022680.029
regulation of kinase activityGO:00435493140.029
single organism cellular localizationGO:19025803320.029
negative regulation of protein modification processGO:00314002000.028
oxidation reduction processGO:00551143960.028
regulation of cellular response to stressGO:00801352440.028
cytokine productionGO:00018162470.028
negative regulation of cellular amino acid metabolic processGO:004576320.028
epidermis morphogenesisGO:004873030.028
ossificationGO:00015031210.028
endocytosisGO:00068971590.027
muscle cell differentiationGO:0042692630.027
regulation of cell morphogenesisGO:00226041530.027
immune responseGO:00069553070.027
cell fate determinationGO:000170930.027
cell fate commitmentGO:0045165270.026
negative regulation of cardioblast cell fate specificationGO:000999710.026
covalent chromatin modificationGO:00165692540.026
protein maturationGO:00516042330.026
nucleoside triphosphate metabolic processGO:00091414220.026
regulation of canonical wnt signaling pathwayGO:0060828880.026
regulation of cellular component biogenesisGO:00440872810.026
mapk cascadeGO:00001652880.026
organic hydroxy compound metabolic processGO:19016151470.025
regulation of protein localizationGO:00328802960.025
positive regulation of myeloid cell differentiationGO:0045639390.025
regulation of nervous system developmentGO:0051960880.025
cellular macromolecule catabolic processGO:00442653800.025
ribonucleotide catabolic processGO:00092614050.025
ras protein signal transductionGO:0007265730.025
immune system developmentGO:00025201950.025
positive regulation of sequence specific dna binding transcription factor activityGO:00510911310.025
metencephalon developmentGO:002203720.024
brain developmentGO:0007420970.024
stem cell developmentGO:0048864690.024
regulation of growthGO:00400081650.024
embryonic hindlimb morphogenesisGO:003511620.023
cellular response to organonitrogen compoundGO:00714171240.023
signal transduction by phosphorylationGO:00230142970.023
nucleoside phosphate catabolic processGO:19012924120.023
neural crest cell migrationGO:000175520.023
ribonucleoside triphosphate catabolic processGO:00092033910.023
purine nucleotide catabolic processGO:00061954050.023
regulation of nucleotide metabolic processGO:00061402690.023
negative regulation of locomotionGO:00400131180.023
regulation of mitotic cell cycleGO:00073461890.023
cell substrate adhesionGO:00315891320.023
hormone secretionGO:0046879650.023
positive regulation of cellular amine metabolic processGO:003324070.022
negative regulation of phosphorus metabolic processGO:00105632670.022
negative regulation of cellular protein metabolic processGO:00322693530.022
purine nucleoside triphosphate metabolic processGO:00091444120.022
regulation of epithelial cell proliferationGO:00506781130.022
regulation of lipid metabolic processGO:0019216960.022
organ formationGO:004864530.022
ribonucleoside triphosphate metabolic processGO:00091994120.022
cell activationGO:00017752130.022
intracellular protein transportGO:00068862700.022
signal releaseGO:0023061700.021
primary neural tube formationGO:001402030.021
neurological system processGO:00508771630.021
negative regulation of phosphorylationGO:00423261740.021
regulation of mapk cascadeGO:00434082620.021
nucleotide catabolic processGO:00091664080.021
mitotic cell cycle processGO:19030472860.021
purine ribonucleoside metabolic processGO:00461284370.021
transmembrane transportGO:00550853990.021
embryonic eye morphogenesisGO:004804820.021
epithelial tube morphogenesisGO:0060562380.021
purine ribonucleoside triphosphate metabolic processGO:00092054110.021
positive regulation of cytokine productionGO:00018191670.021
neuromuscular junction developmentGO:000752830.021
posttranscriptional regulation of gene expressionGO:00106082130.021
regulation of system processGO:00440571010.021
positive regulation of epithelial cell proliferationGO:0050679650.021
wound healingGO:00420601150.020
positive regulation of hydrolase activityGO:00513453310.020
homeostasis of number of cellsGO:0048872400.020
osteoblast differentiationGO:0001649920.020
cerebellum developmentGO:002154920.020
membrane organizationGO:00610242920.020
negative regulation of phosphate metabolic processGO:00459362670.020
erythrocyte homeostasisGO:0034101310.020
myeloid cell homeostasisGO:0002262340.020
hemostasisGO:0007599760.020
purine ribonucleotide catabolic processGO:00091544040.020
regulation of cell divisionGO:00513021160.020
cellular response to dna damage stimulusGO:00069743790.020
purine ribonucleoside triphosphate catabolic processGO:00092073910.020
chemical homeostasisGO:00488783060.020
regulation of epithelial to mesenchymal transitionGO:0010717370.020
ribonucleoside catabolic processGO:00424544060.020
positive regulation of cellular catabolic processGO:00313312840.020
palate developmentGO:0060021130.020
embryonic camera type eye morphogenesisGO:004859620.019
nucleoside catabolic processGO:00091644080.019
response to external biotic stimulusGO:00432072610.019
muscle fiber developmentGO:0048747160.019
peptidyl tyrosine modificationGO:00182121700.019
cation transportGO:00068123310.019
positive regulation of nucleotide metabolic processGO:00459812300.019
morphogenesis of an epitheliumGO:0002009600.019
regulation of establishment of protein localizationGO:00702012420.019
negative regulation of protein phosphorylationGO:00019331400.019
cellular response to transforming growth factor beta stimulusGO:0071560940.019
protein processingGO:00164852260.019
regulation of cell morphogenesis involved in differentiationGO:0010769830.019
neuroblast proliferationGO:000740540.018
regulation of response to woundingGO:19030341010.018
cellular response to hormone stimulusGO:00328701250.018
compound eye developmentGO:004874910.018
thymus developmentGO:004853830.018
salivary gland morphogenesisGO:000743540.018
regulation of cytoplasmic transportGO:19036491490.018
regulation of cell adhesionGO:00301551660.018
embryonic camera type eye formationGO:006090020.018
cell divisionGO:00513011680.018
inner ear morphogenesisGO:004247240.018
positive regulation of cell developmentGO:0010720920.018
positive regulation of protein phosphorylationGO:00019343130.018
muscle cell developmentGO:0055001290.018
glycosyl compound catabolic processGO:19016584130.018
neural tube formationGO:000184130.018
positive regulation of protein transportGO:00512221350.018
organophosphate catabolic processGO:00464344300.018
mesodermal cell fate specificationGO:000750120.018
neural tube closureGO:000184330.018
regenerationGO:003109940.017
ion transmembrane transportGO:00342203380.017
renal system developmentGO:0072001630.017
morphogenesis of a polarized epitheliumGO:000173830.017
organic hydroxy compound biosynthetic processGO:1901617710.017
endomembrane system organizationGO:00102561960.017
regulation of lipid biosynthetic processGO:0046890470.017
nucleoside triphosphate catabolic processGO:00091433940.017
biomineral tissue developmentGO:0031214390.017
negative regulation of cell migrationGO:00303361020.017
peripheral nervous system developmentGO:000742220.017
maintenance of locationGO:00512351120.017
regulation of protein serine threonine kinase activityGO:00719001790.017
cell projection organizationGO:00300302520.017
regulation of cell growthGO:00015581350.017
cellular protein catabolic processGO:00442572610.017
response to organonitrogen compoundGO:00102431560.016
response to lipidGO:00339932060.016
skeletal system morphogenesisGO:0048705240.016
cardiac ventricle formationGO:000321120.016
response to cytokineGO:00340972320.016
glycerolipid metabolic processGO:00464861070.016
regulation of protein complex assemblyGO:00432541470.016
muscle tissue developmentGO:0060537620.016
actin cytoskeleton organizationGO:00300362070.016
response to oxygen levelsGO:00704821000.016
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.016
intracellular receptor signaling pathwayGO:00305221040.016
positive regulation of secretionGO:00510471160.016
response to decreased oxygen levelsGO:0036293960.016
steroid metabolic processGO:0008202940.016
heart morphogenesisGO:0003007480.016
positive regulation of secretion by cellGO:19035321080.016
central nervous system developmentGO:00074171230.016
peptide transportGO:0015833740.016
acylglycerol metabolic processGO:0006639270.016
somitogenesisGO:000175620.016
epithelial cell proliferationGO:00506731280.016
guanosine containing compound catabolic processGO:19010692390.016
dephosphorylationGO:00163112090.016
endocardial cushion developmentGO:000319730.016
negative regulation of intracellular signal transductionGO:19025321830.016
limbic system developmentGO:002176130.016
oocyte differentiationGO:000999420.016
dna repairGO:00062811980.015
purine containing compound catabolic processGO:00725234110.015
appendage morphogenesisGO:0035107160.015
lipid transportGO:0006869900.015
nucleus organizationGO:0006997280.015
regulation of protein catabolic processGO:00421761550.015
regulation of vesicle mediated transportGO:00606271300.015
cellular response to cytokine stimulusGO:00713451810.015
positive regulation of transferase activityGO:00513472270.015
positive regulation of nucleotide catabolic processGO:00308131850.015
protein localization to organelleGO:00333652800.015
response to toxic substanceGO:0009636370.015
aortic valve developmentGO:000317630.015
negative regulation of secretionGO:0051048580.015
connective tissue developmentGO:0061448390.015
positive regulation of purine nucleotide metabolic processGO:19005442270.015
reproductive processGO:00224141060.015
gtp catabolic processGO:00061842370.015
cell cycle phase transitionGO:00447701730.015
endodermal cell fate commitmentGO:000171140.015
taxisGO:00423301570.015
negative regulation of catalytic activityGO:00430863350.015
cellular response to lipidGO:00713961270.015
negative regulation of cell adhesionGO:0007162640.015
gtp metabolic processGO:00460392390.015
blastocyst formationGO:000182530.015
positive regulation of wnt signaling pathwayGO:0030177540.015
proteolysis involved in cellular protein catabolic processGO:00516032440.015
regulation of chromatin modificationGO:1903308510.014
positive regulation of purine nucleotide catabolic processGO:00331231850.014
sex determinationGO:000753030.014
spermatid differentiationGO:004851540.014
negative regulation of cardiac cell fate specificationGO:200004410.014
regulation of intracellular transportGO:00323861950.014
regulation of peptidase activityGO:00525471800.014
oocyte developmentGO:004859910.014
circulatory system processGO:00030131130.014
regulation of transferase activityGO:00513383550.014
regulation of nucleoside metabolic processGO:00091182090.014
purine nucleoside catabolic processGO:00061523980.014
sensory perceptionGO:00076001030.014
purine ribonucleoside catabolic processGO:00461303980.014
lipid localizationGO:00108761060.014
reactive oxygen species biosynthetic processGO:190340940.014
protein oligomerizationGO:00512591730.014
cell part morphogenesisGO:00329901370.014
nucleocytoplasmic transportGO:00069131760.014
positive regulation of mapk cascadeGO:00434101900.014
positive regulation of proteolysisGO:00458621420.014
positive regulation of cellular component biogenesisGO:00440891580.014
carbohydrate derivative biosynthetic processGO:19011372070.014
negative regulation of canonical wnt signaling pathwayGO:0090090550.014
negative regulation of wnt signaling pathwayGO:0030178690.014
positive regulation of peptidase activityGO:0010952880.014
regulation of chromosome organizationGO:00330441030.014
negative regulation of cellular component movementGO:00512711060.014
forebrain neuron differentiationGO:002187930.014
sensory organ developmentGO:0007423520.014
regulation of cell projection organizationGO:00313441070.014
odontogenesisGO:0042476250.014
pharynx developmentGO:006046510.014
head developmentGO:00603221080.014
amide transportGO:0042886760.014
negative regulation of kidney developmentGO:009018520.014
pituitary gland developmentGO:002198320.014
plasma membrane organizationGO:00070091150.014
positive regulation of synaptic transmissionGO:005080640.014
tube closureGO:006060630.014
cardiac muscle cell contractionGO:008600340.014
regulation of immune responseGO:00507762010.014
cellular macromolecular complex assemblyGO:00346223240.014
positive regulation of epithelial cell proliferation involved in wound healingGO:006005430.014
negative regulation of phosphatidylinositol 3 kinase signalingGO:001406740.014
peptide hormone secretionGO:0030072500.014
erythrocyte differentiationGO:0030218280.014
mitotic cell cycle phase transitionGO:00447721620.013
protein importGO:00170381300.013
protein modification by small protein conjugationGO:00324463420.013
nuclear transportGO:00511691790.013
regulation of protein kinase activityGO:00458592890.013
organic acid biosynthetic processGO:0016053970.013
muscle system processGO:0003012810.013
protein localization to membraneGO:00726571600.013
regulation of heart growthGO:006042040.013
positive regulation of protein kinase activityGO:00458601900.013
i kappab kinase nf kappab signalingGO:00072491660.013
positive regulation of cell cycleGO:00457871400.013
reactive oxygen species metabolic processGO:0072593750.013
cell projection morphogenesisGO:00488581290.013
motor neuron axon guidanceGO:000804520.013
midgut developmentGO:000749410.013
sensory perception of painGO:001923340.013
somatic stem cell maintenanceGO:003501940.013
positive regulation of cysteine type endopeptidase activityGO:2001056790.013
negative regulation of cell growthGO:0030308830.013
kidney developmentGO:0001822530.013
regulation of cholesterol metabolic processGO:009018140.013
cellular response to external stimulusGO:00714961110.013
purine nucleoside triphosphate catabolic processGO:00091463920.013
cell growthGO:00160491600.013
cellular protein complex assemblyGO:00436231880.013
regulation of cytoskeleton organizationGO:00514931770.013
regulation of cysteine type endopeptidase activityGO:20001161270.013
rhythmic behaviorGO:000762220.013
peptide secretionGO:0002790510.013
memoryGO:000761330.013
spermatid developmentGO:000728640.013
regulation of cell activationGO:00508651250.013
negative regulation of mitotic cell cycleGO:00459301020.013
cardiac cell fate commitmentGO:006091170.013
protein catabolic processGO:00301633250.013
protein ubiquitinationGO:00165673140.013
negative regulation of secretion by cellGO:1903531520.013

TWIST2 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
musculoskeletal system diseaseDOID:172230.101
connective tissue diseaseDOID:651090.041
nervous system diseaseDOID:8634310.022
sensory system diseaseDOID:00501552030.022
eye and adnexa diseaseDOID:14921500.021
eye diseaseDOID:56141490.021
bone diseaseDOID:0080001880.018
bone development diseaseDOID:0080006550.018
disease of metabolismDOID:00146672950.018
muscle tissue diseaseDOID:661130.017
muscular diseaseDOID:00800001140.017
disease of cellular proliferationDOID:145661740.017
cancerDOID:1621670.017
myopathyDOID:4231040.016
organ system cancerDOID:00506861640.014
congenital muscular dystrophyDOID:0050557220.014
muscular dystrophyDOID:9884510.014
central nervous system diseaseDOID:3311860.013