Homo sapiens

34 known processes

TDP1

tyrosyl-DNA phosphodiesterase 1

(Aliases: FLJ11090,MGC104252)

TDP1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
dna repairGO:00062811980.654
cellular response to dna damage stimulusGO:00069743790.550
microtubule based processGO:00070172100.145
regulation of mitotic cell cycleGO:00073461890.116
dna recombinationGO:0006310770.114
organophosphate catabolic processGO:00464344300.087
mitotic cell cycle phase transitionGO:00447721620.083
base excision repairGO:0006284210.083
mitotic sister chromatid segregationGO:0000070530.081
female gamete generationGO:000729220.080
regulation of cell cycleGO:00517263930.076
nuclear divisionGO:00002801280.076
microtubule cytoskeleton organizationGO:00002261760.071
cellular response to endogenous stimulusGO:00714953360.068
mitotic cell cycle processGO:19030472860.067
organelle fissionGO:00482851490.065
double strand break repairGO:00063021010.064
nucleoside phosphate catabolic processGO:19012924120.062
nucleic acid phosphodiester bond hydrolysisGO:00903051020.060
mitotic cell cycleGO:00002783260.060
post embryonic developmentGO:000979120.060
meiotic chromosome segregationGO:004513240.056
carbohydrate derivative biosynthetic processGO:19011372070.056
response to abiotic stimulusGO:00096283360.056
cellular protein complex assemblyGO:00436231880.054
glycosyl compound catabolic processGO:19016584130.050
regulation of cell cycle processGO:00105642660.049
anatomical structure formation involved in morphogenesisGO:00486462840.048
cellular ketone metabolic processGO:0042180800.047
purine nucleotide catabolic processGO:00061954050.047
histone acetylationGO:0016573930.047
single organism cellular localizationGO:19025803320.046
regulation of microtubule based processGO:0032886740.046
nucleotide catabolic processGO:00091664080.044
histone modificationGO:00165702510.044
purine containing compound catabolic processGO:00725234110.043
chromosome segregationGO:00070591140.043
organophosphate biosynthetic processGO:00904071630.043
determination of adult lifespanGO:000834020.043
nervous system developmentGO:00073992930.042
sister chromatid segregationGO:0000819540.041
purine ribonucleoside triphosphate catabolic processGO:00092073910.041
protein catabolic processGO:00301633250.041
cellular amine metabolic processGO:0044106410.040
segmentationGO:003528240.040
purine nucleoside triphosphate catabolic processGO:00091463920.038
nucleoside triphosphate catabolic processGO:00091433940.038
regulation of protein localizationGO:00328802960.038
cell cycle phase transitionGO:00447701730.038
negative regulation of cellular component organizationGO:00511292350.037
cellular macromolecule catabolic processGO:00442653800.037
nucleoside phosphate biosynthetic processGO:19012931090.036
purine nucleoside catabolic processGO:00061523980.036
nucleoside monophosphate metabolic processGO:00091231910.036
cell activationGO:00017752130.036
meiosis iGO:000712740.036
regulation of proteolysisGO:00301622930.035
establishment of organelle localizationGO:0051656590.034
mitotic nuclear divisionGO:00070671190.034
dna dependent dna replicationGO:0006261440.034
regulation of microtubule cytoskeleton organizationGO:0070507610.033
purine nucleoside monophosphate metabolic processGO:00091261860.033
protein processingGO:00164852260.033
double strand break repair via homologous recombinationGO:0000724500.032
mitotic cell cycle checkpointGO:0007093680.032
single organism carbohydrate metabolic processGO:00447231930.032
regulation of cellular amino acid metabolic processGO:000652160.031
oogenesisGO:004847720.030
positive regulation of hydrolase activityGO:00513453310.030
negative regulation of cell cycle processGO:00109481210.030
negative regulation of cellular protein metabolic processGO:00322693530.029
negative regulation of protein metabolic processGO:00512483910.029
positive regulation of immune system processGO:00026842830.029
anatomical structure homeostasisGO:00602491000.028
ribonucleoside triphosphate catabolic processGO:00092033910.028
regulation of meiotic cell cycleGO:005144540.028
regulation of response to dna damage stimulusGO:2001020940.028
enzyme linked receptor protein signaling pathwayGO:00071673030.027
dna damage checkpointGO:0000077680.027
nucleoside catabolic processGO:00091644080.027
immune system developmentGO:00025201950.027
recombinational repairGO:0000725500.027
purine ribonucleoside metabolic processGO:00461284370.026
sex determinationGO:000753030.026
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.026
purine ribonucleoside monophosphate metabolic processGO:00091671860.025
regulation of mitotic cell cycle phase transitionGO:19019901180.025
chromatin organizationGO:00063253510.025
nucleoside triphosphate metabolic processGO:00091414220.025
negative regulation of cell cycleGO:00457861930.025
positive regulation of apoptotic processGO:00430652460.024
oocyte developmentGO:004859910.023
protein autophosphorylationGO:00467771230.023
negative regulation of dna metabolic processGO:0051053570.023
maintenance of location in cellGO:0051651620.023
regulation of dna metabolic processGO:00510521530.023
positive regulation of cell deathGO:00109422630.023
response to oxygen containing compoundGO:19017003690.023
attachment of spindle microtubules to kinetochoreGO:0008608170.023
regulation of cellular response to stressGO:00801352440.023
embryo developmentGO:00097901230.023
ribonucleotide catabolic processGO:00092614050.022
ribonucleoside monophosphate metabolic processGO:00091611870.022
single organism membrane organizationGO:00448022680.022
nucleus organizationGO:0006997280.022
regulation of proteasomal protein catabolic processGO:0061136870.022
negative regulation of cellular catabolic processGO:0031330830.022
spindle organizationGO:0007051530.022
negative regulation of protein maturationGO:19033181420.022
immune responseGO:00069553070.022
leukocyte activationGO:00453211640.022
regulation of protein processingGO:00706131500.022
proteasomal protein catabolic processGO:00104981760.021
mrna metabolic processGO:00160711750.021
regulation of cell divisionGO:00513021160.021
regulation of cellular amine metabolic processGO:0033238110.021
blastocyst developmentGO:000182430.021
purine nucleoside triphosphate metabolic processGO:00091444120.021
ribonucleoside catabolic processGO:00424544060.020
proteolysis involved in cellular protein catabolic processGO:00516032440.020
nucleotide excision repairGO:0006289310.020
positive regulation of cellular amino acid metabolic processGO:004576430.020
somatic diversification of immunoglobulins involved in immune responseGO:000220830.020
nucleoside monophosphate catabolic processGO:00091251590.020
regulation of cellular component movementGO:00512703340.020
regulation of immune responseGO:00507762010.020
negative regulation of programmed cell deathGO:00430693210.020
regulation of chromosome segregationGO:0051983440.020
positive regulation of developmental processGO:00510943140.020
protein maturationGO:00516042330.020
cell morphogenesisGO:00009022960.020
negative regulation of cell cycle phase transitionGO:1901988890.020
cell projection organizationGO:00300302520.020
cellular protein catabolic processGO:00442572610.019
nucleotide biosynthetic processGO:00091651090.019
response to growth factorGO:00708482050.019
response to radiationGO:00093141510.019
purine ribonucleotide catabolic processGO:00091544040.019
locomotory behaviorGO:000762610.019
organelle assemblyGO:00709251760.019
regulation of cellular ketone metabolic processGO:0010565500.019
mitochondrion organizationGO:00070051560.019
negative regulation of proteolysisGO:00458611320.019
cellular response to growth factor stimulusGO:00713631970.018
intracellular mrna localizationGO:000829810.018
multicellular organismal agingGO:001025930.018
protein localization to organelleGO:00333652800.018
positive regulation of response to dna damage stimulusGO:2001022430.018
response to biotic stimulusGO:00096072760.018
endocytosisGO:00068971590.018
cellular amino acid metabolic processGO:00065201160.018
purine ribonucleoside catabolic processGO:00461303980.018
cellular response to oxygen containing compoundGO:19017012760.018
anterior posterior axis specificationGO:000994820.018
endomembrane system organizationGO:00102561960.018
oocyte differentiationGO:000999420.018
ribonucleoside triphosphate metabolic processGO:00091994120.017
negative regulation of mitotic cell cycle phase transitionGO:1901991850.017
atp metabolic processGO:00460341760.017
regulation of viral processGO:00507921030.017
chromatin modificationGO:00165682980.017
carbohydrate metabolic processGO:00059752070.017
striated muscle myosin thick filament assemblyGO:007168820.017
negative regulation of organelle organizationGO:00106391260.017
reciprocal dna recombinationGO:003582540.017
protein glycosylationGO:0006486620.017
regulation of proteolysis involved in cellular protein catabolic processGO:1903050910.017
positive regulation of nucleotide metabolic processGO:00459812300.017
cell divisionGO:00513011680.017
protein targetingGO:00066051870.017
defense responseGO:00069523150.017
internal peptidyl lysine acetylationGO:0018393970.016
intracellular protein transportGO:00068862700.016
cardiovascular system developmentGO:00723582620.016
negative regulation of immune system processGO:00026831360.016
cellular response to radiationGO:0071478650.016
anterior posterior axis specification embryoGO:000859520.016
covalent chromatin modificationGO:00165692540.016
peptidyl lysine acetylationGO:00183941010.016
regulation of protein maturationGO:19033171500.016
maintenance of protein locationGO:0045185570.016
single organism reproductive processGO:0044702980.016
vesicle mediated transportGO:00161923710.016
negative regulation of phosphate metabolic processGO:00459362670.016
cellular macromolecular complex assemblyGO:00346223240.016
adult locomotory behaviorGO:000834410.016
mitotic dna integrity checkpointGO:0044774300.016
positive regulation of cellular amine metabolic processGO:003324070.016
regulation of cellular component biogenesisGO:00440872810.015
lipid metabolic processGO:00066293810.015
regulation of defense responseGO:00313471540.015
regulation of leukocyte activationGO:00026941150.015
establishment or maintenance of cytoskeleton polarityGO:003095230.015
regulation of dna repairGO:0006282470.015
positive regulation of immune responseGO:00507781590.015
mitotic sister chromatid separationGO:0051306180.015
cellular response to abiotic stimulusGO:00712141170.015
glycerolipid metabolic processGO:00464861070.015
regulation of nucleotide catabolic processGO:00308112050.015
cytoplasmic transportGO:00164823790.015
protein dephosphorylationGO:0006470810.015
dna geometric changeGO:0032392320.015
glycosylationGO:0070085710.015
internal protein amino acid acetylationGO:00064751010.015
cell part morphogenesisGO:00329901370.015
atp catabolic processGO:00062001570.015
regulation of nucleoside metabolic processGO:00091182090.015
protein import into nucleusGO:00066061040.015
secretionGO:00469032540.015
positive regulation of mapk cascadeGO:00434101900.014
growthGO:00400072020.014
purine nucleoside monophosphate catabolic processGO:00091281580.014
ras protein signal transductionGO:0007265730.014
negative regulation of phosphorus metabolic processGO:00105632670.014
regulation of lymphocyte activationGO:00512491030.014
regulation of establishment of protein localizationGO:00702012420.014
glycoprotein biosynthetic processGO:0009101910.014
protein targeting to nucleusGO:00447441040.014
regulation of protein catabolic processGO:00421761550.014
circulatory system developmentGO:00723592620.014
negative regulation of hydrolase activityGO:00513461820.014
response to oxygen levelsGO:00704821000.014
positive regulation of purine nucleotide metabolic processGO:19005442270.014
reciprocal meiotic recombinationGO:000713140.014
positive regulation of immunoglobulin productionGO:000263940.013
gtp catabolic processGO:00061842370.013
negative regulation of catalytic activityGO:00430863350.013
ubiquitin dependent protein catabolic processGO:00065112060.013
positive regulation of catabolic processGO:00098963100.013
protein homooligomerizationGO:00512601000.013
organonitrogen compound biosynthetic processGO:19015662000.013
glycoprotein metabolic processGO:00091001100.013
cellular lipid metabolic processGO:00442553030.013
central nervous system developmentGO:00074171230.013
regulation of cell motilityGO:20001452990.013
nuclear importGO:00511701060.013
neurogenesisGO:00220081690.013
response to external biotic stimulusGO:00432072610.013
regulation of nuclear divisionGO:0051783650.013
regulation of nucleotide metabolic processGO:00061402690.013
regulation of multi organism processGO:00439001570.013
purine ribonucleoside triphosphate metabolic processGO:00092054110.013
dna integrity checkpointGO:0031570710.013
protein oligomerizationGO:00512591730.013
positive regulation of cellular catabolic processGO:00313312840.012
positive regulation of immunoglobulin mediated immune responseGO:000289140.012
membrane organizationGO:00610242920.012
response to organonitrogen compoundGO:00102431560.012
brain developmentGO:0007420970.012
epithelium developmentGO:00604292270.012
response to hypoxiaGO:0001666960.012
dephosphorylationGO:00163112090.012
regulation of gene expression epigeneticGO:0040029730.012
regulation of purine nucleotide catabolic processGO:00331212050.012
neuromuscular junction developmentGO:000752830.012
cellular component disassemblyGO:0022411920.012
regulation of cell cycle phase transitionGO:19019871260.012
apoptotic signaling pathwayGO:00971902680.012
cellular response to organonitrogen compoundGO:00714171240.012
regulation of kinase activityGO:00435493140.012
establishment of protein localization to organelleGO:00725941720.012
establishment or maintenance of microtubule cytoskeleton polarityGO:003095120.012
chemical homeostasisGO:00488783060.012
regenerationGO:003109940.012
cell developmentGO:00484683280.012
regulation of meiosisGO:004002030.012
microtubule anchoringGO:0034453240.012
regulation of purine nucleotide metabolic processGO:19005422640.012
posttranscriptional regulation of gene expressionGO:00106082130.012
maintenance of locationGO:00512351120.011
protein acylationGO:00435431380.011
protein localization to nucleusGO:00345041360.011
hematopoietic or lymphoid organ developmentGO:00485341860.011
spindle elongationGO:005123140.011
reproductionGO:0000003630.011
cell projection morphogenesisGO:00488581290.011
hemopoiesisGO:00300971800.011
cytokine productionGO:00018162470.011
regulation of intracellular transportGO:00323861950.011
cell cycle checkpointGO:00000751170.011
regulation of cytoskeleton organizationGO:00514931770.011
ribonucleotide biosynthetic processGO:0009260810.011
cellular component morphogenesisGO:00329893140.011
regulation of intracellular protein transportGO:00331571230.011
dna catabolic processGO:0006308490.011
guanosine containing compound metabolic processGO:19010682440.011
actin filament based processGO:00300292240.011
positive regulation of protein transportGO:00512221350.011
amine metabolic processGO:0009308440.011
head developmentGO:00603221080.011
lipid biosynthetic processGO:00086101770.011
response to other organismGO:00517072610.011
maintenance of protein location in cellGO:0032507560.010
negative regulation of apoptotic processGO:00430663160.010
positive regulation of nucleoside metabolic processGO:00459791860.010
neuron differentiationGO:00301821380.010
negative regulation of mitotic cell cycleGO:00459301020.010
regulation of locomotionGO:00400123290.010
dna strand elongation involved in dna replicationGO:000627130.010
oxidation reduction processGO:00551143960.010
establishment or maintenance of cell polarityGO:0007163310.010
immune effector processGO:00022521590.010
signal transduction in response to dna damageGO:0042770570.010
positive regulation of nucleotide catabolic processGO:00308131850.010
ribose phosphate biosynthetic processGO:0046390820.010

TDP1 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
inherited metabolic disorderDOID:6552420.055
disease of metabolismDOID:00146672950.055
disease of cellular proliferationDOID:145661740.053
cancerDOID:1621670.050
organ system cancerDOID:00506861640.022
breast cancerDOID:1612210.022
thoracic cancerDOID:5093210.022
neuropathyDOID:870520.014
nervous system diseaseDOID:8634310.014
central nervous system diseaseDOID:3311860.012
disease of mental healthDOID:150700.011
neurodegenerative diseaseDOID:12891020.004
spinocerebellar degenerationDOID:2478270.001
spinocerebellar ataxiaDOID:1441260.001