Homo sapiens

19 known processes

L2HGDH

L-2-hydroxyglutarate dehydrogenase

(Aliases: DURANIN,FLJ12618,C14orf160)

L2HGDH biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular amino acid metabolic processGO:00065201160.061
post embryonic developmentGO:000979120.049
cellular ketone metabolic processGO:0042180800.042
multicellular organismal agingGO:001025930.040
determination of adult lifespanGO:000834020.039
amine metabolic processGO:0009308440.038
regulation of cellular ketone metabolic processGO:0010565500.036
regulation of cellular amino acid metabolic processGO:000652160.035
cellular amine metabolic processGO:0044106410.034
cellular response to dna damage stimulusGO:00069743790.032
regulation of cellular amine metabolic processGO:0033238110.032
purine nucleotide catabolic processGO:00061954050.031
purine containing compound catabolic processGO:00725234110.030
nucleoside triphosphate metabolic processGO:00091414220.030
purine nucleoside triphosphate metabolic processGO:00091444120.029
purine ribonucleoside catabolic processGO:00461303980.028
female gamete generationGO:000729220.028
ribonucleoside triphosphate metabolic processGO:00091994120.028
positive regulation of cellular amino acid metabolic processGO:004576430.028
ribonucleoside catabolic processGO:00424544060.027
lipid metabolic processGO:00066293810.027
nucleoside triphosphate catabolic processGO:00091433940.027
organophosphate catabolic processGO:00464344300.027
ribonucleotide catabolic processGO:00092614050.027
glycosyl compound catabolic processGO:19016584130.026
locomotory behaviorGO:000762610.026
purine ribonucleoside metabolic processGO:00461284370.026
purine ribonucleoside triphosphate metabolic processGO:00092054110.026
nucleoside phosphate catabolic processGO:19012924120.026
neuromuscular junction developmentGO:000752830.026
ribonucleoside triphosphate catabolic processGO:00092033910.025
oogenesisGO:004847720.025
negative regulation of cellular protein metabolic processGO:00322693530.025
mitochondrion organizationGO:00070051560.025
purine nucleoside triphosphate catabolic processGO:00091463920.024
cellular macromolecule catabolic processGO:00442653800.024
nucleotide catabolic processGO:00091664080.024
purine ribonucleoside triphosphate catabolic processGO:00092073910.023
cytoplasmic transportGO:00164823790.023
purine ribonucleotide catabolic processGO:00091544040.023
regenerationGO:003109940.023
negative regulation of protein metabolic processGO:00512483910.023
positive regulation of cellular amine metabolic processGO:003324070.023
positive regulation of hydrolase activityGO:00513453310.023
negative regulation of catalytic activityGO:00430863350.023
cellular macromolecular complex assemblyGO:00346223240.022
segmentationGO:003528240.022
protein catabolic processGO:00301633250.021
oxidation reduction processGO:00551143960.021
purine nucleoside catabolic processGO:00061523980.021
negative regulation of cell deathGO:00605483450.021
single organism cellular localizationGO:19025803320.021
chemical homeostasisGO:00488783060.021
nucleoside catabolic processGO:00091644080.021
cellular lipid metabolic processGO:00442553030.020
transmembrane transportGO:00550853990.020
regulation of transferase activityGO:00513383550.020
chromatin organizationGO:00063253510.020
protein localization to organelleGO:00333652800.020
positive regulation of catabolic processGO:00098963100.020
negative regulation of phosphorus metabolic processGO:00105632670.020
memoryGO:000761330.019
ras protein signal transductionGO:0007265730.019
carbohydrate metabolic processGO:00059752070.019
negative regulation of programmed cell deathGO:00430693210.019
system processGO:00030083490.019
microtubule based processGO:00070172100.019
negative regulation of phosphate metabolic processGO:00459362670.019
anterior posterior axis specificationGO:000994820.019
small gtpase mediated signal transductionGO:0007264780.018
dephosphorylationGO:00163112090.018
monocarboxylic acid metabolic processGO:00327871850.018
membrane organizationGO:00610242920.018
regulation of cell cycle processGO:00105642660.018
response to abiotic stimulusGO:00096283360.018
regulation of protein kinase activityGO:00458592890.018
negative regulation of cellular amine metabolic processGO:003323930.018
small molecule biosynthetic processGO:00442831570.018
regulation of kinase activityGO:00435493140.018
organonitrogen compound biosynthetic processGO:19015662000.018
ribonucleoside monophosphate metabolic processGO:00091611870.018
mitotic cell cycleGO:00002783260.018
cellular protein catabolic processGO:00442572610.018
positive regulation of cellular catabolic processGO:00313312840.018
dna repairGO:00062811980.018
positive regulation of transportGO:00510503360.018
negative regulation of cellular amino acid metabolic processGO:004576320.018
cation transportGO:00068123310.018
histone modificationGO:00165702510.017
regulation of cellular response to stressGO:00801352440.017
positive regulation of phosphorylationGO:00423273940.017
immune responseGO:00069553070.017
positive regulation of cellular component organizationGO:00511303760.017
purine nucleoside monophosphate metabolic processGO:00091261860.017
intracellular protein transportGO:00068862700.017
nervous system developmentGO:00073992930.017
small molecule catabolic processGO:0044282920.017
regulation of proteolysisGO:00301622930.017
cellular component morphogenesisGO:00329893140.017
protein maturationGO:00516042330.017
adult locomotory behaviorGO:000834410.017
carbohydrate derivative biosynthetic processGO:19011372070.017
cell morphogenesisGO:00009022960.017
cellular protein complex assemblyGO:00436231880.017
spermatid differentiationGO:004851540.017
negative regulation of apoptotic processGO:00430663160.017
positive regulation of cell deathGO:00109422630.016
single organism carbohydrate metabolic processGO:00447231930.016
regulation of nucleotide metabolic processGO:00061402690.016
guanosine containing compound catabolic processGO:19010692390.016
regulation of protein localizationGO:00328802960.016
regulation of cellular component movementGO:00512703340.016
single organism membrane organizationGO:00448022680.016
positive regulation of apoptotic processGO:00430652460.016
regulation of purine nucleotide metabolic processGO:19005422640.016
gtp metabolic processGO:00460392390.016
covalent chromatin modificationGO:00165692540.016
rho protein signal transductionGO:0007266260.016
peripheral nervous system developmentGO:000742220.016
positive regulation of nucleotide metabolic processGO:00459812300.016
signal transduction by phosphorylationGO:00230142970.016
ion homeostasisGO:00508012300.016
regulation of cell cycleGO:00517263930.016
hindbrain developmentGO:003090230.016
purine ribonucleoside monophosphate metabolic processGO:00091671860.016
positive regulation of programmed cell deathGO:00430682490.016
ion transmembrane transportGO:00342203380.016
guanosine containing compound metabolic processGO:19010682440.016
proteolysis involved in cellular protein catabolic processGO:00516032440.016
cofactor metabolic processGO:0051186870.016
nucleoside monophosphate metabolic processGO:00091231910.016
cardiac muscle cell contractionGO:008600340.015
compound eye developmentGO:004874910.015
blastoderm segmentationGO:000735020.015
atp metabolic processGO:00460341760.015
vesicle mediated transportGO:00161923710.015
negative regulation of multicellular organismal processGO:00512413170.015
defense responseGO:00069523150.015
response to oxygen containing compoundGO:19017003690.015
cell projection organizationGO:00300302520.015
metal ion transportGO:00300012720.015
protein processingGO:00164852260.015
embryonic epithelial tube formationGO:000183840.015
regulation of cell motilityGO:20001452990.015
apoptotic signaling pathwayGO:00971902680.015
maintenance of locationGO:00512351120.015
negative regulation of intracellular signal transductionGO:19025321830.015
nerve developmentGO:002167540.015
actin filament based processGO:00300292240.015
innate immune responseGO:00450871780.015
mitotic cell cycle processGO:19030472860.015
oocyte developmentGO:004859910.015
negative regulation of protein modification processGO:00314002000.015
carboxylic acid biosynthetic processGO:0046394970.015
negative regulation of hydrolase activityGO:00513461820.015
nitrogen compound transportGO:00717051910.015
anatomical structure formation involved in morphogenesisGO:00486462840.014
regulation of establishment of protein localizationGO:00702012420.014
protein targetingGO:00066051870.014
spermatid developmentGO:000728640.014
mapk cascadeGO:00001652880.014
protein modification by small protein conjugationGO:00324463420.014
purine nucleoside monophosphate catabolic processGO:00091281580.014
posttranscriptional regulation of gene expressionGO:00106082130.014
chromatin modificationGO:00165682980.014
coenzyme metabolic processGO:0006732650.014
regulation of cellular component biogenesisGO:00440872810.014
positive regulation of purine nucleotide metabolic processGO:19005442270.014
gtp catabolic processGO:00061842370.014
negative regulation of cell proliferationGO:00082852280.014
reactive oxygen species biosynthetic processGO:190340940.014
release of cytoplasmic sequestered nf kappabGO:000858840.014
oocyte differentiationGO:000999420.014
lipid biosynthetic processGO:00086101770.014
secretionGO:00469032540.014
protein oligomerizationGO:00512591730.014
microtubule cytoskeleton organizationGO:00002261760.014
positive regulation of protein phosphorylationGO:00019343130.014
cellular response to oxygen containing compoundGO:19017012760.014
tripartite regional subdivisionGO:000735120.014
rna processingGO:00063962550.014
positive regulation of nucleoside metabolic processGO:00459791860.013
regulation of response to external stimulusGO:00321012220.013
biological adhesionGO:00226103310.013
cell adhesionGO:00071553250.013
proteasomal protein catabolic processGO:00104981760.013
organic acid biosynthetic processGO:0016053970.013
regulation of cell differentiationGO:00455953930.013
organophosphate biosynthetic processGO:00904071630.013
response to cytokineGO:00340972320.013
protein ubiquitinationGO:00165673140.013
regulation of mapk cascadeGO:00434082620.013
rhythmic behaviorGO:000762220.013
regulation of nucleoside metabolic processGO:00091182090.013
positive regulation of transferase activityGO:00513472270.013
sex determinationGO:000753030.013
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.013
regulation of purine nucleotide catabolic processGO:00331212050.013
establishment of protein localization to organelleGO:00725941720.013
carboxylic acid catabolic processGO:0046395710.013
regulation of cytokine productionGO:00018172320.013
organelle assemblyGO:00709251760.013
negative regulation of cellular component organizationGO:00511292350.013
response to fungusGO:000962040.013
photoreceptor cell differentiationGO:004653020.013
regulation of anatomical structure morphogenesisGO:00226032860.013
regulation of protein transportGO:00512232130.013
cellular response to endogenous stimulusGO:00714953360.013
modification dependent macromolecule catabolic processGO:00436322120.013
ribonucleoside monophosphate catabolic processGO:00091581580.013
cellular response to cytokine stimulusGO:00713451810.013
cation transmembrane transportGO:00986552380.013
associative learningGO:000830610.013
cellular homeostasisGO:00197251960.013
cell fate determinationGO:000170930.013
positive regulation of immune system processGO:00026842830.013
cytokine productionGO:00018162470.013
morphogenesis of embryonic epitheliumGO:001633140.013
reactive nitrogen species metabolic processGO:200105730.013
negative regulation of phosphorylationGO:00423261740.013
cation homeostasisGO:00550801890.013
positive regulation of cell proliferationGO:00082843010.013
positive regulation of purine nucleotide catabolic processGO:00331231850.013
negative regulation of cell cycleGO:00457861930.012
neurotransmitter secretionGO:000726940.012
protein homooligomerizationGO:00512601000.012
anterior posterior axis specification embryoGO:000859520.012
anion transportGO:00068201610.012
cell growthGO:00160491600.012
nucleoside monophosphate catabolic processGO:00091251590.012
regulation of intracellular transportGO:00323861950.012
regulation of nucleotide catabolic processGO:00308112050.012
regulation of locomotionGO:00400123290.012
neurological system processGO:00508771630.012
positive regulation of synaptic transmissionGO:005080640.012
actin filament based movementGO:0030048170.012
cell projection assemblyGO:00300311260.012
endomembrane system organizationGO:00102561960.012
regulation of peptidase activityGO:00525471800.012
regulation of cell migrationGO:00303342890.012
motor neuron axon guidanceGO:000804520.012
fatty acid metabolic processGO:00066311150.012
actin mediated cell contractionGO:0070252120.012
methylationGO:00322591060.012
organic hydroxy compound metabolic processGO:19016151470.012
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.012
rna interferenceGO:001624640.012
tissue regenerationGO:004224630.012
alpha amino acid metabolic processGO:1901605720.012
secretion by cellGO:00329402260.012
cell developmentGO:00484683280.012
regulation of immune responseGO:00507762010.012
positive regulation of kinase activityGO:00336742040.012
regulation of endopeptidase activityGO:00525481700.012
regulation of cytoskeleton organizationGO:00514931770.012
organ formationGO:004864530.012
positive regulation of developmental processGO:00510943140.012
metencephalon developmentGO:002203720.012
negative regulation of transportGO:00510511760.012
meiosis iGO:000712740.012
regulation of reactive oxygen species biosynthetic processGO:190342630.012
nuclear transportGO:00511691790.012
inner ear morphogenesisGO:004247240.012
syncytium formation by plasma membrane fusionGO:000076820.012
positive regulation of gtp catabolic processGO:00331261660.012
sulfur compound metabolic processGO:00067901010.012
regulation of dna metabolic processGO:00510521530.012
reactive oxygen species metabolic processGO:0072593750.011
developmental programmed cell deathGO:001062330.011
regulation of protein catabolic processGO:00421761550.011
regulation of secretionGO:00510461940.011
response to nitrogen compoundGO:19016981840.011
glycoprotein metabolic processGO:00091001100.011
negative regulation of transferase activityGO:00513481240.011
circadian behaviorGO:004851220.011
inorganic ion transmembrane transportGO:00986602310.011
regulation of gtp catabolic processGO:00331241800.011
nucleocytoplasmic transportGO:00069131760.011
metal ion homeostasisGO:00550651690.011
atp catabolic processGO:00062001570.011
ubiquitin dependent protein catabolic processGO:00065112060.011
somitogenesisGO:000175620.011
response to axon injuryGO:004867810.011
regulation of neural precursor cell proliferationGO:200017740.011
regulation of gtpase activityGO:00430871800.011
response to external biotic stimulusGO:00432072610.011
modification dependent protein catabolic processGO:00199412090.011
macromolecule methylationGO:0043414970.011
mrna metabolic processGO:00160711750.011
purine ribonucleoside monophosphate catabolic processGO:00091691580.011
positive regulation of cellular component movementGO:00512721810.011
multi organism cellular processGO:00447641560.011
cell part morphogenesisGO:00329901370.011
morphogenesis of a polarized epitheliumGO:000173830.011
response to biotic stimulusGO:00096072760.011
positive regulation of organelle organizationGO:00106381950.011
positive regulation of cellular component biogenesisGO:00440891580.011
regulation of protein maturationGO:19033171500.011
sensory perception of smellGO:000760820.011
regulation of sequence specific dna binding transcription factor activityGO:00510902110.011
cellular chemical homeostasisGO:00550821800.011
negative regulation of protein phosphorylationGO:00019331400.011
enzyme linked receptor protein signaling pathwayGO:00071673030.011
meiotic chromosome segregationGO:004513240.011
alcohol metabolic processGO:00060661140.011
cellular metal ion homeostasisGO:00068751460.011
positive regulation of gtpase activityGO:00435471660.011
regulation of protein processingGO:00706131500.011
symbiosis encompassing mutualism through parasitismGO:00444031560.011
visual behaviorGO:000763220.011
limbic system developmentGO:002176130.011
cellular cation homeostasisGO:00300031630.011
positive regulation of nucleotide catabolic processGO:00308131850.011
growthGO:00400072020.011
positive regulation of cell migrationGO:00303351720.010
regulation of apoptotic signaling pathwayGO:20012331750.010
salivary gland morphogenesisGO:000743540.010
response to growth factorGO:00708482050.010
cilium morphogenesisGO:0060271750.010
sensory perception of painGO:001923340.010
positive regulation of cell differentiationGO:00455972110.010
cerebellum developmentGO:002154920.010
interspecies interaction between organismsGO:00444191560.010
response to radiationGO:00093141510.010
sequestering of metal ionGO:0051238240.010
regulation of synaptic plasticityGO:004816730.010
neural tube closureGO:000184330.010
establishment or maintenance of bipolar cell polarityGO:006124520.010
regulation of meiotic cell cycleGO:005144540.010
response to organic cyclic compoundGO:00140702040.010
neural tube formationGO:000184130.010
epithelium developmentGO:00604292270.010
cell divisionGO:00513011680.010
engulfment of apoptotic cellGO:004365220.010
long term memoryGO:000761620.010
regulation of cytoplasmic transportGO:19036491490.010
positive regulation of reactive oxygen species biosynthetic processGO:190342820.010
translationGO:00064121320.010
cell projection morphogenesisGO:00488581290.010
organelle fissionGO:00482851490.010
regulation of protein serine threonine kinase activityGO:00719001790.010
inorganic cation transmembrane transportGO:00986621940.010
neuroblast proliferationGO:000740540.010

L2HGDH disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:00146672950.039
inherited metabolic disorderDOID:6552420.036
nervous system diseaseDOID:8634310.023
sensory system diseaseDOID:00501552030.023
musculoskeletal system diseaseDOID:172230.021
disease of cellular proliferationDOID:145661740.020
cancerDOID:1621670.020
organ system cancerDOID:00506861640.019
central nervous system diseaseDOID:3311860.019
eye and adnexa diseaseDOID:14921500.017
immune system diseaseDOID:29141550.016
eye diseaseDOID:56141490.016
amino acid metabolic disorderDOID:9252500.015
connective tissue diseaseDOID:651090.014
neurodegenerative diseaseDOID:12891020.013
retinal diseaseDOID:56791180.012
muscle tissue diseaseDOID:661130.012
muscular diseaseDOID:00800001140.012
bone diseaseDOID:0080001880.012
hematopoietic system diseaseDOID:741000.012
myopathyDOID:4231040.012
retinal degenerationDOID:8466890.012
cardiovascular system diseaseDOID:12871060.011
2 hydroxyglutaric aciduriaDOID:005057330.001