Homo sapiens

0 known processes

OGDH

oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)

(Aliases: OGDC,E1k,AKGDH)

OGDH biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
oxidation reduction processGO:00551143960.292
Rat
determination of adult lifespanGO:000834020.142
post embryonic developmentGO:000979120.094
single organism membrane organizationGO:00448022680.088
cellular lipid metabolic processGO:00442553030.085
single organism cellular localizationGO:19025803320.073
multicellular organismal agingGO:001025930.071
monocarboxylic acid metabolic processGO:00327871850.068
amine metabolic processGO:0009308440.065
nucleoside triphosphate metabolic processGO:00091414220.064
ras protein signal transductionGO:0007265730.063
endomembrane system organizationGO:00102561960.059
regulation of cellular ketone metabolic processGO:0010565500.057
membrane organizationGO:00610242920.055
generation of precursor metabolites and energyGO:0006091680.054
Rat
lipid biosynthetic processGO:00086101770.053
cellular amine metabolic processGO:0044106410.053
purine nucleoside triphosphate catabolic processGO:00091463920.052
lipid metabolic processGO:00066293810.052
tricarboxylic acid metabolic processGO:007235040.051
actin filament based processGO:00300292240.051
female gamete generationGO:000729220.050
intracellular protein transportGO:00068862700.050
purine nucleoside triphosphate metabolic processGO:00091444120.049
protein localization to membraneGO:00726571600.049
negative regulation of protein metabolic processGO:00512483910.048
small gtpase mediated signal transductionGO:0007264780.048
energy derivation by oxidation of organic compoundsGO:0015980430.047
Rat
secretion by cellGO:00329402260.047
oogenesisGO:004847720.046
cell developmentGO:00484683280.044
organophosphate catabolic processGO:00464344300.043
purine ribonucleotide catabolic processGO:00091544040.042
glycosyl compound catabolic processGO:19016584130.041
cofactor metabolic processGO:0051186870.041
Rat
cellular homeostasisGO:00197251960.040
cation transportGO:00068123310.040
cytoplasmic transportGO:00164823790.040
nucleotide catabolic processGO:00091664080.040
cellular chemical homeostasisGO:00550821800.040
response to oxygen containing compoundGO:19017003690.040
cellular amino acid metabolic processGO:00065201160.040
positive regulation of hydrolase activityGO:00513453310.039
purine ribonucleoside triphosphate metabolic processGO:00092054110.039
ribonucleoside catabolic processGO:00424544060.038
response to abiotic stimulusGO:00096283360.038
mitotic cell cycle processGO:19030472860.038
purine nucleoside catabolic processGO:00061523980.038
purine ribonucleoside metabolic processGO:00461284370.037
ion homeostasisGO:00508012300.037
plasma membrane organizationGO:00070091150.037
negative regulation of catalytic activityGO:00430863350.036
organic hydroxy compound metabolic processGO:19016151470.036
cell morphogenesisGO:00009022960.036
chemical homeostasisGO:00488783060.036
purine nucleotide catabolic processGO:00061954050.035
cation homeostasisGO:00550801890.035
nervous system developmentGO:00073992930.035
system processGO:00030083490.035
negative regulation of phosphate metabolic processGO:00459362670.034
cation transmembrane transportGO:00986552380.034
neuroblast proliferationGO:000740540.034
protein maturationGO:00516042330.033
segmentationGO:003528240.033
locomotory behaviorGO:000762610.033
cell fate determinationGO:000170930.032
regulation of cellular amino acid metabolic processGO:000652160.032
transmembrane transportGO:00550853990.032
microtubule based processGO:00070172100.032
negative regulation of cellular protein metabolic processGO:00322693530.032
nucleoside triphosphate catabolic processGO:00091433940.031
inorganic ion transmembrane transportGO:00986602310.031
coenzyme metabolic processGO:0006732650.031
Rat
nucleoside phosphate catabolic processGO:19012924120.031
cellular ketone metabolic processGO:0042180800.031
purine ribonucleoside catabolic processGO:00461303980.031
anatomical structure formation involved in morphogenesisGO:00486462840.030
regulation of proteolysisGO:00301622930.030
dephosphorylationGO:00163112090.030
vesicle mediated transportGO:00161923710.030
nucleoside catabolic processGO:00091644080.030
alcohol metabolic processGO:00060661140.029
regulation of small gtpase mediated signal transductionGO:00510561560.029
purine containing compound catabolic processGO:00725234110.029
ribonucleotide catabolic processGO:00092614050.028
protein processingGO:00164852260.028
small molecule biosynthetic processGO:00442831570.028
positive regulation of cellular amine metabolic processGO:003324070.028
metal ion transportGO:00300012720.028
cellular component morphogenesisGO:00329893140.028
protein localization to organelleGO:00333652800.028
lipid oxidationGO:0034440330.028
reactive nitrogen species metabolic processGO:200105730.028
negative regulation of programmed cell deathGO:00430693210.027
mitotic cell cycleGO:00002783260.027
regulation of ras protein signal transductionGO:00465781550.027
regulation of cellular amine metabolic processGO:0033238110.026
positive regulation of transportGO:00510503360.026
dicarboxylic acid metabolic processGO:0043648290.026
Rat
neuromuscular junction developmentGO:000752830.026
positive regulation of immune system processGO:00026842830.026
adult locomotory behaviorGO:000834410.026
positive regulation of cellular catabolic processGO:00313312840.025
negative regulation of apoptotic processGO:00430663160.025
negative regulation of cell deathGO:00605483450.025
immune responseGO:00069553070.025
positive regulation of cellular amino acid metabolic processGO:004576430.025
lipid modificationGO:0030258840.025
response to hormoneGO:00097251750.024
purine ribonucleoside triphosphate catabolic processGO:00092073910.024
regenerationGO:003109940.024
regulation of secretion by cellGO:19035301770.024
inorganic cation transmembrane transportGO:00986621940.024
negative regulation of phosphorylationGO:00423261740.024
regulation of cell cycleGO:00517263930.024
tricarboxylic acid cycleGO:000609940.024
Rat
carbohydrate metabolic processGO:00059752070.023
peripheral nervous system developmentGO:000742220.023
positive regulation of catabolic processGO:00098963100.023
regulation of growthGO:00400081650.023
regulation of purine nucleotide metabolic processGO:19005422640.023
negative regulation of hydrolase activityGO:00513461820.023
negative regulation of intracellular signal transductionGO:19025321830.023
regulation of secretionGO:00510461940.023
ion transmembrane transportGO:00342203380.023
ribonucleoside triphosphate catabolic processGO:00092033910.023
anion transportGO:00068201610.023
nitrogen compound transportGO:00717051910.023
regulation of cell differentiationGO:00455953930.023
biological adhesionGO:00226103310.023
regulation of transporter activityGO:0032409820.023
protein localization to plasma membraneGO:0072659930.022
cardiac muscle cell contractionGO:008600340.022
circulatory system developmentGO:00723592620.022
actin cytoskeleton organizationGO:00300362070.022
oocyte developmentGO:004859910.022
positive regulation of steroid hormone biosynthetic processGO:009003120.022
negative regulation of phosphorus metabolic processGO:00105632670.022
organonitrogen compound biosynthetic processGO:19015662000.022
negative regulation of protein modification processGO:00314002000.022
wnt signaling pathwayGO:00160551560.022
organ formationGO:004864530.022
regulation of kinase activityGO:00435493140.022
regulation of protein localizationGO:00328802960.022
cell cell signalingGO:00072671550.022
guanosine containing compound catabolic processGO:19010692390.021
blastoderm segmentationGO:000735020.021
cellular macromolecule catabolic processGO:00442653800.021
cellular response to oxygen containing compoundGO:19017012760.021
cell projection organizationGO:00300302520.021
protein targetingGO:00066051870.021
positive regulation of cellular component organizationGO:00511303760.021
negative regulation of protein processingGO:00109551420.021
response to mercury ionGO:004668940.021
cellular macromolecular complex assemblyGO:00346223240.021
cell adhesionGO:00071553250.021
spermatid differentiationGO:004851540.021
negative regulation of multicellular organismal processGO:00512413170.020
cellular respirationGO:0045333210.020
Rat
oocyte differentiationGO:000999420.020
regulation of transferase activityGO:00513383550.020
memoryGO:000761330.020
stem cell divisionGO:001714520.020
steroid metabolic processGO:0008202940.020
establishment of protein localization to membraneGO:00901501210.020
regulation of cell cycle processGO:00105642660.020
establishment of protein localization to plasma membraneGO:0090002680.020
proteasomal protein catabolic processGO:00104981760.020
anterior posterior axis specificationGO:000994820.019
regulation of protein processingGO:00706131500.019
steroid biosynthetic processGO:0006694460.019
cellular response to dna damage stimulusGO:00069743790.019
microtubule cytoskeleton organizationGO:00002261760.019
generation of neuronsGO:00486991520.019
cellular protein catabolic processGO:00442572610.019
regulation of gtpase activityGO:00430871800.019
single organism membrane fusionGO:0044801370.019
regulation of anatomical structure morphogenesisGO:00226032860.019
negative regulation of cellular component organizationGO:00511292350.019
cellular protein complex assemblyGO:00436231880.019
positive regulation of hormone biosynthetic processGO:004688640.019
gtp metabolic processGO:00460392390.019
protein catabolic processGO:00301633250.019
protein acylationGO:00435431380.019
regulation of cellular component biogenesisGO:00440872810.019
organic acid biosynthetic processGO:0016053970.019
regulation of protein maturationGO:19033171500.018
regulation of establishment of protein localizationGO:00702012420.018
regulation of homeostatic processGO:00328441210.018
oxidoreduction coenzyme metabolic processGO:0006733190.018
Rat
divalent metal ion transportGO:00708381520.018
cellular metal ion homeostasisGO:00068751460.018
regulation of neuroblast proliferationGO:190269230.018
epithelium developmentGO:00604292270.018
negative regulation of cellular amine metabolic processGO:003323930.018
negative regulation of proteolysisGO:00458611320.018
metal ion homeostasisGO:00550651690.018
reactive oxygen species metabolic processGO:0072593750.018
spermatid developmentGO:000728640.018
response to organonitrogen compoundGO:00102431560.018
myosin filament assemblyGO:003103420.018
cardiovascular system developmentGO:00723582620.018
regulation of ion transmembrane transportGO:00347651320.018
organophosphate biosynthetic processGO:00904071630.018
secretionGO:00469032540.018
regulation of peptidase activityGO:00525471800.018
gtp catabolic processGO:00061842370.017
positive regulation of gtp catabolic processGO:00331261660.017
cellular ion homeostasisGO:00068731680.017
negative regulation of cellular amino acid metabolic processGO:004576320.017
regulation of cellular response to stressGO:00801352440.017
regulation of ion homeostasisGO:2000021730.017
negative regulation of cell proliferationGO:00082852280.017
response to organic cyclic compoundGO:00140702040.017
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.017
positive regulation of nucleotide metabolic processGO:00459812300.017
negative regulation of transportGO:00510511760.017
modification dependent protein catabolic processGO:00199412090.017
axon cargo transportGO:000808820.017
mitochondrion organizationGO:00070051560.017
positive regulation of phosphorylationGO:00423273940.017
fatty acid metabolic processGO:00066311150.016
apoptotic signaling pathwayGO:00971902680.016
positive regulation of smoothened signaling pathwayGO:004588040.016
tripartite regional subdivisionGO:000735120.016
guanosine containing compound metabolic processGO:19010682440.016
rna interferenceGO:001624640.016
neurogenesisGO:00220081690.016
response to nitrogen compoundGO:19016981840.016
regulation of cellular component movementGO:00512703340.016
proteolysis involved in cellular protein catabolic processGO:00516032440.016
ribonucleoside triphosphate metabolic processGO:00091994120.016
positive regulation of gtpase activityGO:00435471660.016
negative regulation of protein maturationGO:19033181420.016
organelle assemblyGO:00709251760.016
ribonucleoside monophosphate metabolic processGO:00091611870.016
positive regulation of secretion by cellGO:19035321080.016
synaptic vesicle exocytosisGO:001607930.016
regulation of neurotransmitter secretionGO:004692830.016
alcohol biosynthetic processGO:0046165520.016
carboxylic acid transportGO:0046942630.016
regulation of cell migrationGO:00303342890.016
anterior posterior axis specification embryoGO:000859520.016
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.016
endosomal transportGO:00161971290.016
regulation of hormone levelsGO:00108171250.015
innate immune responseGO:00450871780.015
nucleocytoplasmic transportGO:00069131760.015
canonical wnt signaling pathwayGO:00600701160.015
actin mediated cell contractionGO:0070252120.015
calcium ion transmembrane transportGO:0070588760.015
positive regulation of chondrocyte differentiationGO:003233240.015
positive regulation of cell deathGO:00109422630.015
positive regulation of cell differentiationGO:00455972110.015
regulation of cytoplasmic transportGO:19036491490.015
positive regulation of developmental processGO:00510943140.015
regulation of protein kinase activityGO:00458592890.015
maintenance of locationGO:00512351120.015
mapk cascadeGO:00001652880.015
cellular response to nitrogen compoundGO:19016991440.015
cellular response to endogenous stimulusGO:00714953360.015
sequestering of metal ionGO:0051238240.015
regulation of locomotionGO:00400123290.015
posttranscriptional regulation of gene expressionGO:00106082130.015
regulation of cell morphogenesisGO:00226041530.015
receptor metabolic processGO:0043112810.015
regulation of dephosphorylationGO:0035303960.015
positive regulation of synaptic transmissionGO:005080640.015
single organism reproductive processGO:0044702980.015
nucleoside monophosphate metabolic processGO:00091231910.015
cellular cation homeostasisGO:00300031630.015
salivary gland morphogenesisGO:000743540.014
neurotransmitter secretionGO:000726940.014
striated muscle myosin thick filament assemblyGO:007168820.014
nuclear transportGO:00511691790.014
negative regulation of organelle organizationGO:00106391260.014
protein secretionGO:0009306980.014
negative regulation of peptidase activityGO:0010466910.014
compound eye developmentGO:004874910.014
rna processingGO:00063962550.014
positive regulation of nucleotide catabolic processGO:00308131850.014
internal protein amino acid acetylationGO:00064751010.014
defense responseGO:00069523150.014
meiotic chromosome segregationGO:004513240.014
leukocyte activationGO:00453211640.014
regulation of nucleoside metabolic processGO:00091182090.014
matingGO:000761810.014
negative regulation of developmental processGO:00510932470.014
regulation of lipid biosynthetic processGO:0046890470.014
regulation of mapk cascadeGO:00434082620.014
purine nucleoside monophosphate metabolic processGO:00091261860.014
pyridine nucleotide metabolic processGO:0019362140.014
Rat
neurological system processGO:00508771630.014
citrate metabolic processGO:000610120.014
sulfur compound metabolic processGO:00067901010.014
Rat
regulation of response to external stimulusGO:00321012220.014
cell projection assemblyGO:00300311260.014
regulation of wnt signaling pathwayGO:00301111230.014
response to axon injuryGO:004867810.014
regulation of protein transportGO:00512232130.014
protein deubiquitinationGO:0016579790.014
sodium ion transmembrane transportGO:0035725590.014
regulation of defense responseGO:00313471540.014
sodium ion transportGO:0006814610.014
atp metabolic processGO:00460341760.013
single organism carbohydrate metabolic processGO:00447231930.013
rhythmic behaviorGO:000762220.013
somitogenesisGO:000175620.013
inner ear morphogenesisGO:004247240.013
ribonucleoside monophosphate catabolic processGO:00091581580.013
regulation of cell motilityGO:20001452990.013
regulation of mitotic cell cycleGO:00073461890.013
motor neuron axon guidanceGO:000804520.013
protein autophosphorylationGO:00467771230.013
mitotic cell cycle phase transitionGO:00447721620.013
golgi vesicle transportGO:0048193800.013
regulation of purine nucleotide catabolic processGO:00331212050.013
purine ribonucleoside monophosphate metabolic processGO:00091671860.013
cell divisionGO:00513011680.013
endochondral bone morphogenesisGO:006035030.013
regulation of synaptic plasticityGO:004816730.013
glycerolipid metabolic processGO:00464861070.013
regulation of ion transmembrane transporter activityGO:0032412720.013
small molecule catabolic processGO:0044282920.013
protein acetylationGO:00064731160.013
organelle localizationGO:0051640840.013
establishment of planar polarityGO:000173630.013
purine nucleoside monophosphate catabolic processGO:00091281580.013
calcium ion transportGO:00068161470.012
response to salt stressGO:000965130.012
monovalent inorganic cation transportGO:00156721280.012
positive regulation of organelle organizationGO:00106381950.012
syncytium formation by plasma membrane fusionGO:000076820.012
regulation of immune responseGO:00507762010.012
carboxylic acid biosynthetic processGO:0046394970.012
cellular response to organonitrogen compoundGO:00714171240.012
ubiquitin dependent protein catabolic processGO:00065112060.012
neuron developmentGO:00486661130.012
regulation of synaptic vesicle exocytosisGO:200030020.012
regulation of nucleotide catabolic processGO:00308112050.012
protein modification by small protein conjugationGO:00324463420.012
embryo developmentGO:00097901230.012
purine ribonucleoside monophosphate catabolic processGO:00091691580.012
chloride transmembrane transportGO:1902476380.012
response to inorganic substanceGO:00100351270.012
positive regulation of protein kinase activityGO:00458601900.012
regulation of ion transportGO:00432691890.012
pyridine containing compound metabolic processGO:0072524180.012
Rat
cell activationGO:00017752130.012
growthGO:00400072020.012
myosin filament organizationGO:003103320.012
regulation of cell developmentGO:00602841610.012
regulation of vesicle mediated transportGO:00606271300.012
regulation of leukocyte activationGO:00026941150.012
regulation of lipid metabolic processGO:0019216960.012
actin filament organizationGO:00070151280.012
positive regulation of secretionGO:00510471160.012
divalent inorganic cation homeostasisGO:00725071360.012
cilium morphogenesisGO:0060271750.012
regulation of metal ion transportGO:00109591200.012
mitotic nuclear divisionGO:00070671190.012
positive regulation of nucleoside metabolic processGO:00459791860.012
organic acid transportGO:0015849650.012
lipid localizationGO:00108761060.012
regulation of nucleotide metabolic processGO:00061402690.012
organelle fissionGO:00482851490.012
covalent chromatin modificationGO:00165692540.012
nuclear exportGO:0051168690.012
response to lipidGO:00339932060.012
positive regulation of protein phosphorylationGO:00019343130.012
oligosaccharide biosynthetic processGO:000931230.012
endocytosisGO:00068971590.012
divalent inorganic cation transportGO:00725111580.012
regulation of reactive oxygen species biosynthetic processGO:190342630.012
circadian behaviorGO:004851220.012
response to cytokineGO:00340972320.012
mrna metabolic processGO:00160711750.012
anterograde axon cargo transportGO:000808910.012
sequestering of calcium ionGO:0051208170.012
regulation of cell activationGO:00508651250.011
hindbrain developmentGO:003090230.011
negative regulation of endopeptidase activityGO:0010951840.011
histone modificationGO:00165702510.011
protein dephosphorylationGO:0006470810.011
reactive oxygen species biosynthetic processGO:190340940.011
protein modification by small protein removalGO:0070646920.011
regulation of ras gtpase activityGO:00323181280.011
detection of muramyl dipeptideGO:003249810.011
modification dependent macromolecule catabolic processGO:00436322120.011
organic hydroxy compound biosynthetic processGO:1901617710.011
synaptic vesicle endocytosisGO:004848820.011
nuclear migrationGO:000709710.011
regulation of cytoskeleton organizationGO:00514931770.011
reproductive processGO:00224141060.011
rho protein signal transductionGO:0007266260.011
establishment or maintenance of apical basal cell polarityGO:003508820.011
regulation of cell adhesionGO:00301551660.011
regulation of reactive oxygen species metabolic processGO:2000377410.011
phospholipid metabolic processGO:0006644990.011
cell part morphogenesisGO:00329901370.011
establishment of protein localization to organelleGO:00725941720.011
establishment or maintenance of cytoskeleton polarityGO:003095230.011
cholesterol metabolic processGO:0008203280.011
nucleus localizationGO:005164710.011
positive regulation of transferase activityGO:00513472270.011
glycoprotein metabolic processGO:00091001100.011
protein oligomerizationGO:00512591730.011
cellular component disassemblyGO:0022411920.011
response to fungusGO:000962040.011
regulation of nucleocytoplasmic transportGO:0046822980.011
long term memoryGO:000761620.011
regulation of neural precursor cell proliferationGO:200017740.011
lipid transportGO:0006869900.011
positive regulation of cell cycleGO:00457871400.011
regulation of nervous system developmentGO:0051960880.011
regulation of actin filament based processGO:00329701410.011
antigen processing and presentation of lipid antigen via mhc class ibGO:004800310.011
muscle system processGO:0003012810.011
regulation of endocytosisGO:0030100720.011
positive regulation of immune responseGO:00507781590.011
head developmentGO:00603221080.011
chromatin organizationGO:00063253510.011
response to other organismGO:00517072610.011
regulation of gtp catabolic processGO:00331241800.011
response to peptideGO:1901652650.011
response to decreased oxygen levelsGO:0036293960.011
regulation of cytokine productionGO:00018172320.011
neuron projection regenerationGO:003110210.010
regulation of synaptic vesicle transportGO:190280330.010
internal peptidyl lysine acetylationGO:0018393970.010
response to metal ionGO:0010038840.010
cellular response to hormone stimulusGO:00328701250.010
demethylationGO:0070988370.010
negative regulation of neural precursor cell proliferationGO:200017810.010
nicotinamide nucleotide metabolic processGO:0046496140.010
Rat
release of cytoplasmic sequestered nf kappabGO:000858840.010
organ morphogenesisGO:00098871470.010
actin filament based movementGO:0030048170.010
signal transduction by phosphorylationGO:00230142970.010
monocarboxylic acid biosynthetic processGO:0072330670.010
morphogenesis of embryonic epitheliumGO:001633140.010
chromatin modificationGO:00165682980.010
sterol metabolic processGO:0016125280.010
regulation of meiotic cell cycleGO:005144540.010
response to growth factorGO:00708482050.010
brain developmentGO:0007420970.010
cell projection morphogenesisGO:00488581290.010
response to woundingGO:00096111680.010

OGDH disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:00146672950.038
central nervous system diseaseDOID:3311860.038
nervous system diseaseDOID:8634310.038
neurodegenerative diseaseDOID:12891020.028
urinary system diseaseDOID:18400.028
musculoskeletal system diseaseDOID:172230.023
muscle tissue diseaseDOID:661130.022
myopathyDOID:4231040.022
muscular diseaseDOID:00800001140.022
inherited metabolic disorderDOID:6552420.020
kidney diseaseDOID:557360.019
cardiovascular system diseaseDOID:12871060.019
disease of cellular proliferationDOID:145661740.018
cancerDOID:1621670.018
sensory system diseaseDOID:00501552030.018
immune system diseaseDOID:29141550.015
neuropathyDOID:870520.014
eye and adnexa diseaseDOID:14921500.014
eye diseaseDOID:56141490.014
retinal diseaseDOID:56791180.014
organ system cancerDOID:00506861640.014
neuromuscular diseaseDOID:440380.011