Homo sapiens

33 known processes

RBX1

ring-box 1, E3 ubiquitin protein ligase

(Aliases: FLJ60363,MGC13357,RNF75,ROC1,MGC1481,BA554C12.1)

RBX1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
protein modification by small protein conjugationGO:00324463420.999
protein neddylationGO:004511670.998
modification dependent protein catabolic processGO:00199412090.998
cellular macromolecule catabolic processGO:00442653800.997
ubiquitin dependent protein catabolic processGO:00065112060.996
protein ubiquitinationGO:00165673140.992
proteolysis involved in cellular protein catabolic processGO:00516032440.988
proteasomal protein catabolic processGO:00104981760.980
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.977
cellular protein catabolic processGO:00442572610.976
scf dependent proteasomal ubiquitin dependent protein catabolic processGO:0031146150.971
cyclin catabolic processGO:000805460.968
protein catabolic processGO:00301633250.928
regulation of ubiquitin protein transferase activityGO:0051438280.923
post embryonic developmentGO:000979120.876
Worm
mitotic cell cycle processGO:19030472860.854
mitotic cell cycleGO:00002783260.828
female gamete generationGO:000729220.796
modification dependent macromolecule catabolic processGO:00436322120.783
regulation of cell cycleGO:00517263930.747
Worm
regulation of cell cycle processGO:00105642660.707
Worm
regulation of meiotic cell cycleGO:005144540.617
Worm
microtubule based processGO:00070172100.605
Worm
determination of adult lifespanGO:000834020.601
Worm
regulation of mitotic cell cycleGO:00073461890.597
Worm
positive regulation of catabolic processGO:00098963100.593
regulation of protein catabolic processGO:00421761550.590
blastoderm segmentationGO:000735020.569
Worm
regulation of protein ubiquitinationGO:0031396950.568
microtubule cytoskeleton organizationGO:00002261760.473
positive regulation of protein modification by small protein conjugation or removalGO:1903322610.472
positive regulation of protein catabolic processGO:0045732750.459
embryo development ending in birth or egg hatchingGO:0009792340.455
Worm
positive regulation of protein ubiquitinationGO:0031398530.454
regulation of ligase activityGO:0051340290.423
embryo developmentGO:00097901230.416
Worm
multicellular organismal agingGO:001025930.371
Worm
regulation of mitosisGO:0007088630.370
Worm
regulation of cell cycle phase transitionGO:19019871260.340
Worm
single organism reproductive processGO:0044702980.340
Worm
meiotic chromosome segregationGO:004513240.337
Worm
regulation of mitotic cell cycle phase transitionGO:19019901180.332
cell developmentGO:00484683280.331
Fly
regulation of protein modification by small protein conjugation or removalGO:19033201070.302
meiotic cell cycleGO:0051321130.287
Worm
mitotic cell cycle phase transitionGO:00447721620.272
dna integrity checkpointGO:0031570710.255
positive regulation of cell cycle processGO:00900681060.254
Worm
anterior posterior axis specificationGO:000994820.254
Worm
growthGO:00400072020.244
anterior posterior axis specification embryoGO:000859520.243
Worm
positive regulation of cell cycleGO:00457871400.239
Worm
multicellular organism reproductionGO:0032504420.228
Worm
neurogenesisGO:00220081690.221
Fly
regulation of metaphase anaphase transition of cell cycleGO:1902099260.210
Worm
positive regulation of proteasomal protein catabolic processGO:1901800350.202
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434710.195
regulation of proteasomal protein catabolic processGO:0061136870.189
ribonucleoprotein complex biogenesisGO:00226131160.181
positive regulation of transferase activityGO:00513472270.176
oogenesisGO:004847720.174
segmentationGO:003528240.173
Worm
reproductive processGO:00224141060.164
Worm
mitotic nuclear divisionGO:00070671190.163
regulation of kinase activityGO:00435493140.150
nervous system developmentGO:00073992930.147
Fly
regulation of growthGO:00400081650.146
protein localization to organelleGO:00333652800.144
histone h2a ubiquitinationGO:0033522170.137
cell cycle phase transitionGO:00447701730.133
Worm
posttranscriptional regulation of gene expressionGO:00106082130.125
gonad developmentGO:0008406340.123
Worm
cell cycle checkpointGO:00000751170.121
positive regulation of meiotic cell cycleGO:005144620.119
Worm
positive regulation of cellular amine metabolic processGO:003324070.112
protein polyubiquitinationGO:00002091100.106
mitotic dna integrity checkpointGO:0044774300.105
dna repairGO:00062811980.105
regulation of proteolysis involved in cellular protein catabolic processGO:1903050910.104
histone h2a monoubiquitinationGO:0035518110.101
multicellular organismal reproductive processGO:0048609400.100
Worm
neuron projection developmentGO:00311751060.098
cell fate commitment involved in pattern specificationGO:006058110.096
negative regulation of cell deathGO:00605483450.092
developmental process involved in reproductionGO:0003006660.091
Worm
organelle fissionGO:00482851490.090
Worm
oocyte differentiationGO:000999420.090
positive regulation of sequence specific dna binding transcription factor activityGO:00510911310.089
cellular amine metabolic processGO:0044106410.088
negative regulation of mitotic cell cycleGO:00459301020.088
cardiovascular system developmentGO:00723582620.087
cellular response to dna damage stimulusGO:00069743790.086
regulation of cellular protein catabolic processGO:1903362960.085
endocytosisGO:00068971590.085
protein importGO:00170381300.082
tripartite regional subdivisionGO:000735120.080
Worm
reproductive structure developmentGO:0048608550.078
Worm
histone monoubiquitinationGO:0010390200.076
regulation of cell divisionGO:00513021160.076
Worm
intracellular receptor signaling pathwayGO:00305221040.074
oocyte developmentGO:004859910.071
cell projection organizationGO:00300302520.071
nuclear transcribed mrna catabolic processGO:0000956480.069
multi organism reproductive processGO:0044703540.067
Worm
nuclear divisionGO:00002801280.066
Worm
covalent chromatin modificationGO:00165692540.065
neuron developmentGO:00486661130.064
Fly
regulation of protein stabilityGO:0031647870.063
sleepGO:003043120.063
single organism cellular localizationGO:19025803320.062
reproductionGO:0000003630.060
Worm
mitotic cell cycle checkpointGO:0007093680.059
cell cell signaling involved in cell fate commitmentGO:004516850.059
nuclear importGO:00511701060.057
histone ubiquitinationGO:0016574310.056
positive regulation of ubiquitin protein transferase activityGO:0051443180.056
establishment of nucleus localizationGO:004002310.056
Worm
blastocyst developmentGO:000182430.054
protein import into nucleusGO:00066061040.053
positive regulation of protein phosphorylationGO:00019343130.051
hematopoietic or lymphoid organ developmentGO:00485341860.051
behaviorGO:00076101120.051
cullin deneddylationGO:001038890.050
nuclear migrationGO:000709710.049
Worm
development of primary sexual characteristicsGO:0045137350.048
Worm
multi organism behaviorGO:0051705140.048
response to biotic stimulusGO:00096072760.044
cellular metal ion homeostasisGO:00068751460.043
protein ubiquitination involved in ubiquitin dependent protein catabolic processGO:0042787370.042
signal transduction by phosphorylationGO:00230142970.042
rna interferenceGO:001624640.042
positive regulation of transportGO:00510503360.042
cell part morphogenesisGO:00329901370.041
regulation of cellular amino acid metabolic processGO:000652160.040
establishment of protein localization to organelleGO:00725941720.040
cerebral cortex radially oriented cell migrationGO:002179910.040
g2 m transition of mitotic cell cycleGO:0000086410.039
generation of neuronsGO:00486991520.039
Fly
meiosis iGO:000712740.038
negative regulation of cell cycle phase transitionGO:1901988890.038
positive regulation of cellular protein catabolic processGO:1903364370.038
positive regulation of cellular amino acid metabolic processGO:004576430.037
negative regulation of immune system processGO:00026831360.036
circulatory system developmentGO:00723592620.036
spermatid differentiationGO:004851540.035
dna replicationGO:00062601160.035
cellular ketone metabolic processGO:0042180800.035
negative regulation of cell cycle processGO:00109481210.034
meiotic nuclear divisionGO:0007126100.034
Worm
protein targetingGO:00066051870.034
sexual reproductionGO:0019953370.034
Worm
receptor mediated endocytosisGO:0006898840.034
regulation of meiosisGO:004002030.033
defense responseGO:00069523150.033
cation homeostasisGO:00550801890.033
spindle organizationGO:0007051530.033
cell projection morphogenesisGO:00488581290.033
regulation of cellular response to stressGO:00801352440.032
cellular macromolecular complex assemblyGO:00346223240.032
mitotic sister chromatid separationGO:0051306180.032
regulation of transferase activityGO:00513383550.032
cytokine productionGO:00018162470.032
chemical homeostasisGO:00488783060.032
immune system developmentGO:00025201950.031
cellular response to endogenous stimulusGO:00714953360.031
ion homeostasisGO:00508012300.031
posttranscriptional gene silencing by rnaGO:0035194250.031
multicellular organismal response to stressGO:003355510.030
glial cell migrationGO:000834740.030
organelle assemblyGO:00709251760.030
cell growthGO:00160491600.030
ncrna processingGO:0034470830.029
negative regulation of apoptotic processGO:00430663160.028
regulation of sister chromatid segregationGO:0033045270.028
Worm
positive regulation of proteolysis involved in cellular protein catabolic processGO:1903052350.027
negative regulation of mitotic cell cycle phase transitionGO:1901991850.026
cellular response to peptideGO:1901653590.026
i kappab kinase nf kappab signalingGO:00072491660.026
neuron remodelingGO:001632220.025
Fly
cellular chemical homeostasisGO:00550821800.025
negative regulation of glial cell proliferationGO:006025320.025
negative regulation of cell cycleGO:00457861930.025
organ formationGO:004864530.025
intracellular protein transportGO:00068862700.025
cell divisionGO:00513011680.024
protein localization to nucleusGO:00345041360.024
positive regulation of cytokine productionGO:00018191670.024
methylationGO:00322591060.024
reproductive system developmentGO:0061458560.024
Worm
dna damage checkpointGO:0000077680.024
cytoplasmic transportGO:00164823790.024
tissue regenerationGO:004224630.024
double strand break repair via homologous recombinationGO:0000724500.024
positive regulation of mitotic cell cycleGO:0045931600.023
protein targeting to nucleusGO:00447441040.023
response to light stimulusGO:0009416870.023
mapk cascadeGO:00001652880.023
regulation of mitotic sister chromatid segregationGO:0033047270.023
Worm
regulation of protein import into nucleusGO:0042306780.023
negative regulation of protein metabolic processGO:00512483910.023
response to abiotic stimulusGO:00096283360.023
negative regulation of transcription from rna polymerase ii promoter in response to hypoxiaGO:006142840.023
negative regulation of catalytic activityGO:00430863350.022
histone modificationGO:00165702510.022
cellular response to oxygen containing compoundGO:19017012760.022
regulation of myeloid cell differentiationGO:0045637810.022
response to organic cyclic compoundGO:00140702040.021
negative regulation of cell growthGO:0030308830.021
regulation of establishment of protein localizationGO:00702012420.021
regulation of gene expression epigeneticGO:0040029730.021
positive regulation of phosphorylationGO:00423273940.021
regulation of nucleocytoplasmic transportGO:0046822980.021
regulation of sequence specific dna binding transcription factor activityGO:00510902110.021
negative regulation of programmed cell deathGO:00430693210.021
regulation of cellular amine metabolic processGO:0033238110.020
multi multicellular organism processGO:0044706180.020
cellular component morphogenesisGO:00329893140.020
protein modification by small protein removalGO:0070646920.020
neurological system processGO:00508771630.020
mrna processingGO:00063971330.019
positive regulation of protein polyubiquitinationGO:190291630.019
positive regulation of nucleotide catabolic processGO:00308131850.019
cell morphogenesisGO:00009022960.019
spermatid developmentGO:000728640.019
neuron differentiationGO:00301821380.019
Fly
response to metal ionGO:0010038840.019
g1 s transition of mitotic cell cycleGO:0000082780.019
response to inorganic substanceGO:00100351270.019
vesicle mediated transportGO:00161923710.019
regulation of cellular component biogenesisGO:00440872810.018
positive regulation of cell proliferationGO:00082843010.018
cell cycle g2 m phase transitionGO:0044839430.018
cellular protein complex assemblyGO:00436231880.018
stress activated protein kinase signaling cascadeGO:0031098940.018
intrinsic apoptotic signaling pathwayGO:00971931270.018
negative regulation of intracellular signal transductionGO:19025321830.017
cell fate determinationGO:000170930.017
establishment of organelle localizationGO:0051656590.017
Worm
response to radiationGO:00093141510.017
system processGO:00030083490.017
mrna splicing via spliceosomeGO:0000398890.017
anterior posterior pattern specificationGO:000995290.017
Worm
hindbrain developmentGO:003090230.016
regulation of cytoplasmic transportGO:19036491490.016
chordate embryonic developmentGO:0043009340.016
protein k63 linked ubiquitinationGO:0070534310.016
positive regulation of programmed cell deathGO:00430682490.016
regulation of chromosome organizationGO:00330441030.016
Worm
regulation of anatomical structure sizeGO:00900661010.016
apoptotic signaling pathwayGO:00971902680.015
cell maturationGO:0048469110.015
Fly
organelle localizationGO:0051640840.015
Worm
regulation of mitotic sister chromatid separationGO:0010965270.015
Worm
positive regulation of ligase activityGO:0051351190.015
cerebral cortex cell migrationGO:002179530.015
behavioral fear responseGO:000166200.014
engulfment of apoptotic cellGO:004365220.014
embryonic axis specificationGO:000057850.014
Worm
guanosine containing compound metabolic processGO:19010682440.014
sex differentiationGO:0007548450.014
Worm
neuromuscular junction developmentGO:000752830.014
transcription factor import into nucleusGO:0042991400.014
stress activated mapk cascadeGO:0051403930.014
neuron projection morphogenesisGO:0048812500.014
negative regulation of growthGO:0045926970.014
vasculature developmentGO:00019441810.013
regulation of epithelial cell proliferationGO:00506781130.013
epithelial cell proliferationGO:00506731280.013
rna catabolic processGO:0006401710.013
amine metabolic processGO:0009308440.013
gene silencingGO:0016458490.013
embryonic pattern specificationGO:000988050.013
Worm
negative regulation of endopeptidase activityGO:0010951840.012
establishment of cell polarityGO:0030010220.012
positive regulation of kinase activityGO:00336742040.012
negative regulation of multicellular organismal processGO:00512413170.012
positive regulation of proteolysisGO:00458621420.012
agingGO:0007568660.012
Worm
cytosolic calcium ion homeostasisGO:0051480890.012
mitotic g2 m transition checkpointGO:004481890.012
maintenance of locationGO:00512351120.012
Fly
immune responseGO:00069553070.012
regulation of protein localizationGO:00328802960.012
response to virusGO:00096151260.012
regulation of cellular component sizeGO:0032535820.012
regulation of cytoskeleton organizationGO:00514931770.012
calcium ion transportGO:00068161470.012
stem cell developmentGO:0048864690.012
regulation of protein processingGO:00706131500.012
cellular response to nitrogen compoundGO:19016991440.011
peptide transportGO:0015833740.011
cellular calcium ion homeostasisGO:00068741170.011
negative regulation of transportGO:00510511760.011
ameboidal type cell migrationGO:00016671350.011
chromatin organizationGO:00063253510.011
regulation of proteolysisGO:00301622930.011
positive regulation of apoptotic processGO:00430652460.011
regulation of centrosome cycleGO:0046605150.011
cellular cation homeostasisGO:00300031630.011
positive regulation of cell deathGO:00109422630.011
cellular process involved in reproduction in multicellular organismGO:0022412150.011
regulation of cellular ketone metabolic processGO:0010565500.011
negative regulation of cellular protein metabolic processGO:00322693530.011
response to oxygen containing compoundGO:19017003690.011
ncrna metabolic processGO:00346601080.011
regionalizationGO:0003002290.011
Worm
response to external biotic stimulusGO:00432072610.011
regulation of protein localization to nucleusGO:1900180850.010
metal ion homeostasisGO:00550651690.010
tissue morphogenesisGO:0048729960.010
hemopoiesisGO:00300971800.010
defense response to other organismGO:00985421290.010
negative regulation of cellular catabolic processGO:0031330830.010
protein stabilizationGO:0050821640.010

RBX1 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
renal cell carcinomaDOID:445080.023
kidney cancerDOID:263110.023
disease of cellular proliferationDOID:145661740.023
hereditary renal cell carcinomaDOID:445560.023
urinary system cancerDOID:3996150.023
renal carcinomaDOID:445180.023
nonpapillary renal cell carcinomaDOID:005038760.023
cancerDOID:1621670.023
organ system cancerDOID:00506861640.023