Homo sapiens

47 known processes

SGMS1

sphingomyelin synthase 1

(Aliases: MGC17342,TMEM23,SMS1,MOB,hmob33,MOB1)

SGMS1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
vesicle mediated transportGO:00161923710.296
membrane organizationGO:00610242920.206
enzyme linked receptor protein signaling pathwayGO:00071673030.166
cell morphogenesisGO:00009022960.155
cell projection organizationGO:00300302520.119
positive regulation of developmental processGO:00510943140.117
neuromuscular junction developmentGO:000752830.114
secretionGO:00469032540.107
nervous system developmentGO:00073992930.104
chemical homeostasisGO:00488783060.102
positive regulation of cellular component organizationGO:00511303760.102
positive regulation of catabolic processGO:00098963100.100
inorganic cation transmembrane transportGO:00986621940.098
regulation of cell differentiationGO:00455953930.094
endosomal transportGO:00161971290.089
cation homeostasisGO:00550801890.089
transmembrane transportGO:00550853990.089
cation transmembrane transportGO:00986552380.088
purine nucleotide catabolic processGO:00061954050.086
actin filament based processGO:00300292240.086
ribonucleoside triphosphate catabolic processGO:00092033910.085
regulation of cell developmentGO:00602841610.079
cation transportGO:00068123310.079
purine ribonucleoside triphosphate metabolic processGO:00092054110.078
small molecule biosynthetic processGO:00442831570.077
nucleoside triphosphate catabolic processGO:00091433940.076
circulatory system developmentGO:00723592620.076
behaviorGO:00076101120.075
single organism membrane organizationGO:00448022680.074
regulation of purine nucleotide metabolic processGO:19005422640.074
positive regulation of cellular catabolic processGO:00313312840.072
oogenesisGO:004847720.070
post embryonic developmentGO:000979120.070
epithelium developmentGO:00604292270.069
response to growth factorGO:00708482050.069
generation of neuronsGO:00486991520.068
cellular homeostasisGO:00197251960.067
positive regulation of transportGO:00510503360.065
protein localization to membraneGO:00726571600.065
biological adhesionGO:00226103310.065
ribonucleoside triphosphate metabolic processGO:00091994120.064
cytoplasmic transportGO:00164823790.064
nucleoside catabolic processGO:00091644080.060
cell developmentGO:00484683280.059
ion homeostasisGO:00508012300.058
ion transmembrane transportGO:00342203380.058
signal transduction by phosphorylationGO:00230142970.057
ribonucleoside catabolic processGO:00424544060.056
neuron projection developmentGO:00311751060.055
kidney developmentGO:0001822530.055
purine ribonucleotide catabolic processGO:00091544040.054
neural crest cell migrationGO:000175520.054
sodium ion transportGO:0006814610.053
guanosine containing compound metabolic processGO:19010682440.053
regulation of protein localizationGO:00328802960.052
nucleoside triphosphate metabolic processGO:00091414220.052
glycosyl compound catabolic processGO:19016584130.051
maintenance of locationGO:00512351120.051
cellular component morphogenesisGO:00329893140.051
positive regulation of gtpase activityGO:00435471660.051
amine metabolic processGO:0009308440.050
protein localization to plasma membraneGO:0072659930.049
organophosphate catabolic processGO:00464344300.048
positive regulation of cellular amino acid metabolic processGO:004576430.047
regulation of establishment of protein localizationGO:00702012420.047
actin cytoskeleton organizationGO:00300362070.047
inorganic ion transmembrane transportGO:00986602310.047
cellular macromolecule catabolic processGO:00442653800.046
purine nucleoside triphosphate metabolic processGO:00091444120.045
regulation of cell cycleGO:00517263930.045
interspecies interaction between organismsGO:00444191560.045
proteasomal protein catabolic processGO:00104981760.045
cellular response to oxygen containing compoundGO:19017012760.043
secretion by cellGO:00329402260.043
nucleotide catabolic processGO:00091664080.043
protein catabolic processGO:00301633250.042
regulation of locomotionGO:00400123290.042
divalent inorganic cation homeostasisGO:00725071360.041
system processGO:00030083490.041
mapk cascadeGO:00001652880.041
digestive system developmentGO:0055123750.041
metal ion transportGO:00300012720.040
neurogenesisGO:00220081690.040
regulation of vesicle mediated transportGO:00606271300.040
memoryGO:000761330.040
cell adhesionGO:00071553250.040
negative regulation of cell proliferationGO:00082852280.039
positive regulation of nucleoside metabolic processGO:00459791860.039
regulation of response to external stimulusGO:00321012220.039
nucleoside phosphate catabolic processGO:19012924120.038
immune responseGO:00069553070.038
positive regulation of programmed cell deathGO:00430682490.038
neuron differentiationGO:00301821380.038
response to cytokineGO:00340972320.038
regulation of secretionGO:00510461940.037
monovalent inorganic cation transportGO:00156721280.037
female gamete generationGO:000729220.037
lipid metabolic processGO:00066293810.037
segmentationGO:003528240.037
regulation of growthGO:00400081650.037
ras protein signal transductionGO:0007265730.037
calcium ion transmembrane transportGO:0070588760.037
tissue morphogenesisGO:0048729960.037
microtubule based processGO:00070172100.037
growthGO:00400072020.036
epithelial tube morphogenesisGO:0060562380.036
positive regulation of cell proliferationGO:00082843010.036
maintenance of protein locationGO:0045185570.036
proteolysis involved in cellular protein catabolic processGO:00516032440.036
response to oxygen containing compoundGO:19017003690.035
embryonic epithelial tube formationGO:000183840.035
protein ubiquitinationGO:00165673140.035
cellular ion homeostasisGO:00068731680.034
endocytosisGO:00068971590.034
regulation of nucleotide metabolic processGO:00061402690.034
regulation of cell migrationGO:00303342890.034
cellular response to starvationGO:0009267580.034
regulation of mapk cascadeGO:00434082620.033
positive regulation of purine nucleotide metabolic processGO:19005442270.033
gtp metabolic processGO:00460392390.033
determination of adult lifespanGO:000834020.033
positive regulation of immune system processGO:00026842830.033
blastoderm segmentationGO:000735020.032
morphogenesis of an epitheliumGO:0002009600.032
negative regulation of protein metabolic processGO:00512483910.032
ubiquitin dependent protein catabolic processGO:00065112060.031
regulation of cellular ketone metabolic processGO:0010565500.031
negative regulation of transportGO:00510511760.031
purine nucleoside triphosphate catabolic processGO:00091463920.031
glycoprotein metabolic processGO:00091001100.030
positive regulation of hydrolase activityGO:00513453310.030
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.030
tube morphogenesisGO:0035239950.030
regulation of transferase activityGO:00513383550.030
long term memoryGO:000761620.030
positive regulation of phosphorylationGO:00423273940.030
heart developmentGO:0007507950.030
modification dependent macromolecule catabolic processGO:00436322120.030
small gtpase mediated signal transductionGO:0007264780.029
somitogenesisGO:000175620.029
regulation of neuron differentiationGO:0045664700.029
digestive tract developmentGO:0048565750.029
positive regulation of cellular amine metabolic processGO:003324070.029
regulation of cellular amino acid metabolic processGO:000652160.028
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.028
purine ribonucleoside catabolic processGO:00461303980.028
cellular divalent inorganic cation homeostasisGO:00725031280.028
central nervous system developmentGO:00074171230.028
lipid transportGO:0006869900.028
locomotory behaviorGO:000762610.028
single organism cell adhesionGO:00986021790.028
regulation of cellular amine metabolic processGO:0033238110.028
neural tube formationGO:000184130.028
neurological system processGO:00508771630.028
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.027
cellular response to external stimulusGO:00714961110.027
cellular macromolecular complex assemblyGO:00346223240.027
ribonucleoside monophosphate metabolic processGO:00091611870.027
cellular protein catabolic processGO:00442572610.027
protein localization to organelleGO:00333652800.027
regulation of cell morphogenesisGO:00226041530.027
ribonucleotide catabolic processGO:00092614050.026
positive regulation of protein phosphorylationGO:00019343130.026
cellular chemical homeostasisGO:00550821800.026
viral processGO:00160321460.026
regulation of multi organism processGO:00439001570.026
calcium ion homeostasisGO:00550741220.025
cellular calcium ion homeostasisGO:00068741170.025
posttranscriptional regulation of gene expressionGO:00106082130.025
actin filament organizationGO:00070151280.025
cell part morphogenesisGO:00329901370.025
cellular protein complex assemblyGO:00436231880.025
renal system developmentGO:0072001630.025
plasma membrane organizationGO:00070091150.025
regulation of purine nucleotide catabolic processGO:00331212050.025
innate immune responseGO:00450871780.025
receptor metabolic processGO:0043112810.025
positive regulation of cell migrationGO:00303351720.025
regulation of protein catabolic processGO:00421761550.025
organic anion transportGO:00157111030.024
muscle cell fate commitmentGO:004269340.024
cell morphogenesis involved in differentiationGO:00009041440.024
phospholipid translocationGO:004533220.024
regulation of secretion by cellGO:19035301770.024
cellular response to glucocorticoid stimulusGO:007138540.024
regulation of cell projection organizationGO:00313441070.024
regulation of cell cycle processGO:00105642660.023
purine ribonucleoside triphosphate catabolic processGO:00092073910.023
multicellular organismal agingGO:001025930.023
positive regulation of cell developmentGO:0010720920.023
regulation of nucleotide catabolic processGO:00308112050.023
single organism cellular localizationGO:19025803320.023
head developmentGO:00603221080.023
regulation of growth rateGO:004000910.023
cholesterol transportGO:0030301390.023
regulation of cellular component biogenesisGO:00440872810.023
Human
purine nucleoside catabolic processGO:00061523980.023
cellular metal ion homeostasisGO:00068751460.023
negative regulation of phosphorylationGO:00423261740.023
positive regulation of cell motilityGO:20001471770.023
chemotaxisGO:00069351570.023
organelle assemblyGO:00709251760.022
negative regulation of phosphate metabolic processGO:00459362670.022
regulation of cell motilityGO:20001452990.022
cardiovascular system developmentGO:00723582620.022
divalent inorganic cation transportGO:00725111580.022
epithelial cell differentiationGO:00308551410.022
peptidyl serine phosphorylationGO:00181051010.022
protein modification by small protein conjugationGO:00324463420.022
regulation of cellular component movementGO:00512703340.022
negative regulation of catalytic activityGO:00430863350.022
cellular response to endogenous stimulusGO:00714953360.022
cellular response to nutrient levelsGO:0031669690.022
positive regulation of ras gtpase activityGO:00323201170.021
ossificationGO:00015031210.021
regulation of cellular response to growth factor stimulusGO:0090287760.021
neural crest cell developmentGO:001403230.021
response to woundingGO:00096111680.021
transforming growth factor beta receptor signaling pathwayGO:0007179760.021
cellular amino acid metabolic processGO:00065201160.021
organic acid biosynthetic processGO:0016053970.021
neuron developmentGO:00486661130.021
multi organism cellular processGO:00447641560.021
positive regulation of locomotionGO:00400171860.021
cellular response to organonitrogen compoundGO:00714171240.021
nitrogen compound transportGO:00717051910.020
anatomical structure formation involved in morphogenesisGO:00486462840.020
regulation of ras gtpase activityGO:00323181280.020
modification dependent protein catabolic processGO:00199412090.020
cellular ketone metabolic processGO:0042180800.020
positive regulation of cell differentiationGO:00455972110.020
negative regulation of intracellular signal transductionGO:19025321830.020
positive regulation of growthGO:0045927580.020
regulation of nervous system developmentGO:0051960880.020
lysosomal transportGO:0007041330.019
maintenance of location in cellGO:0051651620.019
oocyte developmentGO:004859910.019
embryonic morphogenesisGO:0048598850.019
response to tumor necrosis factorGO:0034612760.019
viral life cycleGO:00190581320.019
response to metal ionGO:0010038840.019
associative learningGO:000830610.018
tube developmentGO:00352951250.018
metal ion homeostasisGO:00550651690.018
regulation of anatomical structure morphogenesisGO:00226032860.018
response to lipidGO:00339932060.018
neuron projection morphogenesisGO:0048812500.018
embryo developmentGO:00097901230.018
negative regulation of cellular component organizationGO:00511292350.018
anterior posterior axis specification embryoGO:000859520.018
cellular response to growth factor stimulusGO:00713631970.018
leukocyte activationGO:00453211640.018
regulation of protein transportGO:00512232130.018
regulation of cell growthGO:00015581350.018
membrane buddingGO:0006900280.018
neurotransmitter secretionGO:000726940.018
regulation of meiotic cell cycleGO:005144540.018
negative regulation of apoptotic processGO:00430663160.018
Mouse
cell cell signalingGO:00072671550.018
cell projection morphogenesisGO:00488581290.017
negative regulation of cellular protein metabolic processGO:00322693530.017
purine containing compound catabolic processGO:00725234110.017
regulation of cell morphogenesis involved in differentiationGO:0010769830.017
morphogenesis of embryonic epitheliumGO:001633140.017
regulation of proteolysisGO:00301622930.017
cellular response to nitrogen compoundGO:19016991440.017
response to nutrient levelsGO:0031667810.017
guanosine containing compound catabolic processGO:19010692390.017
tripartite regional subdivisionGO:000735120.017
angiogenesisGO:00015251470.017
compound eye developmentGO:004874910.017
synaptic transmissionGO:0007268610.016
response to salt stressGO:000965130.016
negative regulation of multicellular organismal processGO:00512413170.016
sterol transportGO:0015918390.016
leukocyte migrationGO:00509001070.016
golgi vesicle transportGO:0048193800.016
positive regulation of protein serine threonine kinase activityGO:00719021190.016
lipid localizationGO:00108761060.016
organ morphogenesisGO:00098871470.016
cell divisionGO:00513011680.016
regulation of kinase activityGO:00435493140.016
response to calcium ionGO:0051592460.016
negative regulation of programmed cell deathGO:00430693210.016
Mouse
taxisGO:00423301570.016
protein autophosphorylationGO:00467771230.016
defense responseGO:00069523150.016
regulation of cellular response to stressGO:00801352440.016
formation of primary germ layerGO:0001704420.016
cellular component disassemblyGO:0022411920.016
muscle structure developmentGO:0061061980.016
positive regulation of cell deathGO:00109422630.015
potassium ion transportGO:0006813620.015
regulation of cell divisionGO:00513021160.015
adult locomotory behaviorGO:000834410.015
positive regulation of reactive oxygen species metabolic processGO:2000379240.015
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781250.015
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092900.015
response to starvationGO:0042594590.015
symbiosis encompassing mutualism through parasitismGO:00444031560.015
peptidyl threonine phosphorylationGO:0018107410.015
peptidyl serine modificationGO:00182091060.015
regulation of neuronal synaptic plasticityGO:004816810.015
regulation of gtp catabolic processGO:00331241800.015
regulation of cytoskeleton organizationGO:00514931770.015
atp catabolic processGO:00062001570.015
response to inorganic substanceGO:00100351270.014
regulation of reactive oxygen species metabolic processGO:2000377410.014
regulation of protein kinase activityGO:00458592890.014
divalent metal ion transportGO:00708381520.014
negative regulation of developmental processGO:00510932470.014
response to extracellular stimulusGO:0009991850.014
hindbrain developmentGO:003090230.014
cellular cation homeostasisGO:00300031630.014
regulation of neuron projection developmentGO:0010975570.014
purine ribonucleoside metabolic processGO:00461284370.014
peptidyl tyrosine phosphorylationGO:00181081700.014
intracellular protein transportGO:00068862700.014
endomembrane system organizationGO:00102561960.014
regulation of defense responseGO:00313471540.014
positive regulation of mapk cascadeGO:00434101900.014
brain developmentGO:0007420970.014
gastrulation with mouth forming secondGO:000170210.014
primary neural tube formationGO:001402030.014
cellular response to extracellular stimulusGO:0031668720.013
cellular lipid metabolic processGO:00442553030.013
calcium ion transportGO:00068161470.013
cellular component assembly involved in morphogenesisGO:0010927730.013
cellular response to fibroblast growth factor stimulusGO:0044344390.013
mitotic cell cycleGO:00002783260.013
response to oxidative stressGO:00069791210.013
renal sodium ion absorptionGO:007029420.013
regulation of nucleoside metabolic processGO:00091182090.013
regulation of gtpase activityGO:00430871800.013
regulation of cell adhesionGO:00301551660.013
regulation of ossificationGO:0030278580.013
mesenchymal cell developmentGO:0014031500.013
syncytium formation by plasma membrane fusionGO:000076820.013
response to other organismGO:00517072610.013
response to endoplasmic reticulum stressGO:0034976490.013
retrograde transport endosome to golgiGO:0042147450.013
nucleocytoplasmic transportGO:00069131760.013
cell activationGO:00017752130.013
positive regulation of apoptotic processGO:00430652460.013
response to transforming growth factor betaGO:0071559940.013
mitochondrion organizationGO:00070051560.012
nuclear transportGO:00511691790.012
negative regulation of cellular amine metabolic processGO:003323930.012
proteasomal ubiquitin independent protein catabolic processGO:001049930.012
positive regulation of nervous system developmentGO:0051962540.012
cell morphogenesis involved in neuron differentiationGO:0048667440.012
positive regulation of proteolysisGO:00458621420.012
blood vessel morphogenesisGO:00485141620.012
steroid metabolic processGO:0008202940.012
regulation of endocytosisGO:0030100720.012
negative regulation of hydrolase activityGO:00513461820.012
establishment or maintenance of epithelial cell apical basal polarityGO:004519710.012
regulation of synaptic plasticityGO:004816730.012
organonitrogen compound biosynthetic processGO:19015662000.012
spermatid differentiationGO:004851540.012
response to nitrogen compoundGO:19016981840.012
organic hydroxy compound transportGO:0015850630.012
negative regulation of protein phosphorylationGO:00019331400.012
positive regulation of protein kinase activityGO:00458601900.012
immune system developmentGO:00025201950.011
regulation of leukocyte migrationGO:0002685630.011
anterior posterior axis specificationGO:000994820.011
covalent chromatin modificationGO:00165692540.011
negative regulation of transferase activityGO:00513481240.011
stem cell differentiationGO:0048863930.011
positive regulation of nucleotide catabolic processGO:00308131850.011
establishment of protein localization to membraneGO:00901501210.011
cell growthGO:00160491600.011
circadian sleep wake cycle sleepGO:005080220.011
negative regulation of growthGO:0045926970.011
protein k48 linked ubiquitinationGO:0070936380.011
response to abiotic stimulusGO:00096283360.011
post golgi vesicle mediated transportGO:0006892360.011
response to external biotic stimulusGO:00432072610.011
positive regulation of gtp catabolic processGO:00331261660.011
protein oligomerizationGO:00512591730.011
ribonucleoside monophosphate catabolic processGO:00091581580.011
rhythmic behaviorGO:000762220.011
regulation of innate immune responseGO:0045088970.011
urogenital system developmentGO:0001655650.011
establishment of protein localization to plasma membraneGO:0090002680.011
nucleoside monophosphate catabolic processGO:00091251590.011
positive regulation of nucleotide metabolic processGO:00459812300.011
regulation of phagocytosis engulfmentGO:006009920.011
regulation of wnt signaling pathwayGO:00301111230.011
exocytosisGO:0006887710.011
mitotic cell cycle processGO:19030472860.011
cytokinesisGO:0000910960.010
maintenance of protein location in cellGO:0032507560.010
reproductive processGO:00224141060.010
positive regulation of organelle organizationGO:00106381950.010
positive regulation of endocytosisGO:0045807420.010
response to transition metal nanoparticleGO:1990267290.010
metencephalon developmentGO:002203720.010
negative regulation of cellular amino acid metabolic processGO:004576320.010
renal sodium ion transportGO:000309620.010
positive regulation of purine nucleotide catabolic processGO:00331231850.010
fibroblast growth factor receptor signaling pathwayGO:0008543260.010
cellular amino acid biosynthetic processGO:0008652300.010
cell migration involved in gastrulationGO:004207410.010
nuclear exportGO:0051168690.010
positive regulation of secretion by cellGO:19035321080.010
carbohydrate derivative biosynthetic processGO:19011372070.010
distal tubule developmentGO:007201740.010
amide transportGO:0042886760.010
rho protein signal transductionGO:0007266260.010

SGMS1 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
musculoskeletal system diseaseDOID:172230.061
eye and adnexa diseaseDOID:14921500.046
nervous system diseaseDOID:8634310.046
eye diseaseDOID:56141490.046
sensory system diseaseDOID:00501552030.046
central nervous system diseaseDOID:3311860.040
neurodegenerative diseaseDOID:12891020.040
retinal diseaseDOID:56791180.027
retinal degenerationDOID:8466890.022
muscle tissue diseaseDOID:661130.019
muscular diseaseDOID:00800001140.019
disease of cellular proliferationDOID:145661740.014
cancerDOID:1621670.014
organ system cancerDOID:00506861640.012