Homo sapiens

26 known processes

MDH2

malate dehydrogenase 2, NAD (mitochondrial)

(Aliases: M-MDH,MOR1,MDH,MGC:3559)

MDH2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
oxidation reduction processGO:00551143960.970
post embryonic developmentGO:000979120.849
Worm Fly
vesicle mediated transportGO:00161923710.725
Worm
nucleotide biosynthetic processGO:00091651090.706
tricarboxylic acid metabolic processGO:007235040.617
generation of precursor metabolites and energyGO:0006091680.478
Fly
nucleoside phosphate biosynthetic processGO:19012931090.416
multicellular organismal agingGO:001025930.341
Worm
mitochondrial transportGO:0006839600.283
monovalent inorganic cation transportGO:00156721280.242
purine ribonucleotide biosynthetic processGO:0009152790.231
atp metabolic processGO:00460341760.227
hydrogen ion transmembrane transportGO:1902600150.208
atp biosynthetic processGO:0006754110.198
determination of adult lifespanGO:000834020.187
Worm
proton transportGO:0015992220.180
cation transmembrane transportGO:00986552380.171
citrate metabolic processGO:000610120.168
ribonucleotide biosynthetic processGO:0009260810.164
endocytosisGO:00068971590.153
Worm
nucleoside monophosphate biosynthetic processGO:0009124190.127
embryo development ending in birth or egg hatchingGO:0009792340.120
Worm
cation transportGO:00068123310.118
mitochondrial membrane organizationGO:0007006400.118
energy derivation by oxidation of organic compoundsGO:0015980430.117
Fly
inorganic ion transmembrane transportGO:00986602310.116
glycosyl compound biosynthetic processGO:1901659270.114
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280690.114
Fly
embryo developmentGO:00097901230.113
Worm
tricarboxylic acid cycleGO:000609940.109
Fly
ribose phosphate biosynthetic processGO:0046390820.107
purine ribonucleoside triphosphate metabolic processGO:00092054110.106
hydrogen transportGO:0006818230.093
purine nucleotide biosynthetic processGO:0006164840.089
organophosphate biosynthetic processGO:00904071630.087
monocarboxylic acid metabolic processGO:00327871850.086
purine ribonucleoside triphosphate biosynthetic processGO:0009206110.085
nucleoside triphosphate biosynthetic processGO:0009142200.083
organic acid catabolic processGO:0016054710.082
nucleoside triphosphate metabolic processGO:00091414220.081
inorganic cation transmembrane transportGO:00986621940.080
carbohydrate derivative biosynthetic processGO:19011372070.074
transmembrane transportGO:00550853990.073
oogenesisGO:004847720.072
purine nucleoside monophosphate biosynthetic processGO:0009127160.071
carboxylic acid catabolic processGO:0046395710.068
energy coupled proton transport down electrochemical gradientGO:001598520.068
purine nucleoside monophosphate metabolic processGO:00091261860.060
purine nucleoside triphosphate metabolic processGO:00091444120.059
ribonucleoside monophosphate metabolic processGO:00091611870.059
receptor mediated endocytosisGO:0006898840.056
Worm
female gamete generationGO:000729220.052
ribonucleoside triphosphate metabolic processGO:00091994120.051
negative regulation of cell proliferationGO:00082852280.048
pyridine nucleotide metabolic processGO:0019362140.047
growthGO:00400072020.046
protein processingGO:00164852260.045
Fly
cell differentiation in spinal cordGO:002151510.045
positive regulation of apoptotic processGO:00430652460.044
Fly
spermatid developmentGO:000728640.042
system processGO:00030083490.042
positive regulation of programmed cell deathGO:00430682490.042
Fly
ion transmembrane transportGO:00342203380.041
homeostasis of number of cellsGO:0048872400.041
response to hormoneGO:00097251750.041
maintenance of locationGO:00512351120.040
regulation of nucleotide metabolic processGO:00061402690.040
anatomical structure homeostasisGO:00602491000.038
protein maturationGO:00516042330.037
Fly
cellular respirationGO:0045333210.037
Fly
cellular amino acid metabolic processGO:00065201160.035
neuromuscular junction developmentGO:000752830.035
purine ribonucleoside biosynthetic processGO:0046129230.035
lipid localizationGO:00108761060.033
immune responseGO:00069553070.032
negative regulation of multicellular organismal processGO:00512413170.032
membrane organizationGO:00610242920.031
tissue homeostasisGO:0001894630.031
organonitrogen compound biosynthetic processGO:19015662000.031
nucleoside biosynthetic processGO:0009163260.031
aspartate metabolic processGO:000653140.029
aerobic respirationGO:000906070.029
Fly
ion homeostasisGO:00508012300.028
dicarboxylic acid catabolic processGO:004364990.028
nucleic acid phosphodiester bond hydrolysisGO:00903051020.027
purine ribonucleoside monophosphate biosynthetic processGO:0009168160.027
rna interferenceGO:001624640.026
nucleoside monophosphate metabolic processGO:00091231910.026
fatty acid metabolic processGO:00066311150.026
reproductionGO:0000003630.026
pyruvate metabolic processGO:0006090260.026
positive regulation of developmental processGO:00510943140.026
regulation of endopeptidase activityGO:00525481700.025
Fly
ribonucleoside monophosphate biosynthetic processGO:0009156170.025
angiogenesisGO:00015251470.025
glutamate metabolic processGO:0006536100.025
ribonucleoside biosynthetic processGO:0042455250.025
response to abiotic stimulusGO:00096283360.025
spermatid differentiationGO:004851540.025
carbohydrate metabolic processGO:00059752070.024
oxidoreduction coenzyme metabolic processGO:0006733190.024
lipid metabolic processGO:00066293810.024
cellular macromolecule catabolic processGO:00442653800.024
reproductive structure developmentGO:0048608550.023
ribonucleoside triphosphate biosynthetic processGO:0009201120.023
purine containing compound biosynthetic processGO:0072522880.022
negative regulation of intracellular signal transductionGO:19025321830.022
defense responseGO:00069523150.022
purine ribonucleoside monophosphate metabolic processGO:00091671860.022
execution phase of apoptosisGO:0097194320.022
purine nucleoside biosynthetic processGO:0042451230.022
excretionGO:000758890.022
regulation of immune responseGO:00507762010.021
cell developmentGO:00484683280.021
Worm Fly
isocitrate metabolic processGO:000610210.021
cell cell signalingGO:00072671550.020
positive regulation of peptidase activityGO:0010952880.020
Fly
adult locomotory behaviorGO:000834410.019
purine nucleoside triphosphate biosynthetic processGO:0009145110.019
positive regulation of hydrolase activityGO:00513453310.019
Fly
purine ribonucleoside metabolic processGO:00461284370.019
positive regulation of cell deathGO:00109422630.019
Fly
positive regulation of cellular component organizationGO:00511303760.019
single organism membrane organizationGO:00448022680.019
mitochondrion organizationGO:00070051560.019
posttranscriptional regulation of gene expressionGO:00106082130.019
aspartate family amino acid catabolic processGO:000906850.018
apoptotic nuclear changesGO:0030262130.018
positive regulation of proteolysisGO:00458621420.018
Fly
dicarboxylic acid biosynthetic processGO:004365040.018
response to biotic stimulusGO:00096072760.017
regulation of cellular amine metabolic processGO:0033238110.017
atp synthesis coupled proton transportGO:001598620.017
actin filament based processGO:00300292240.017
Worm
multicellular organismal reproductive processGO:0048609400.017
response to virusGO:00096151260.016
biological adhesionGO:00226103310.016
reproductive processGO:00224141060.016
secretion by cellGO:00329402260.016
response to lipidGO:00339932060.016
epithelial cell differentiationGO:00308551410.016
regulation of proteolysisGO:00301622930.016
Fly
dicarboxylic acid metabolic processGO:0043648290.015
anion transportGO:00068201610.015
purine ribonucleoside catabolic processGO:00461303980.015
secretionGO:00469032540.014
negative regulation of developmental processGO:00510932470.014
cellular component disassembly involved in execution phase of apoptosisGO:0006921130.014
intracellular receptor signaling pathwayGO:00305221040.014
cellular amide metabolic processGO:0043603690.014
mitochondrial respiratory chain complex i biogenesisGO:0097031160.014
cellular divalent inorganic cation homeostasisGO:00725031280.014
dna catabolic processGO:0006308490.014
glutamate biosynthetic processGO:000653730.014
epithelial cell proliferationGO:00506731280.014
myoblast fusionGO:000752010.013
multicellular organism reproductionGO:0032504420.013
cellular protein complex assemblyGO:00436231880.013
Worm
regulation of kinase activityGO:00435493140.013
intrinsic apoptotic signaling pathwayGO:00971931270.013
regulation of apoptotic signaling pathwayGO:20012331750.013
cellular ion homeostasisGO:00068731680.013
small molecule catabolic processGO:0044282920.013
positive regulation of cysteine type endopeptidase activityGO:2001056790.013
Fly
lipid catabolic processGO:0016042840.013
protein localization to organelleGO:00333652800.013
intracellular protein transportGO:00068862700.013
regulation of protein stabilityGO:0031647870.013
regulation of nucleoside metabolic processGO:00091182090.013
cellular response to dna damage stimulusGO:00069743790.013
regulation of peptidase activityGO:00525471800.012
Fly
regulation of transferase activityGO:00513383550.012
positive regulation of organelle organizationGO:00106381950.012
nucleoside catabolic processGO:00091644080.012
multicellular organismal homeostasisGO:0048871670.012
agingGO:0007568660.012
Worm
negative regulation of transportGO:00510511760.012
response to other organismGO:00517072610.012
cofactor metabolic processGO:0051186870.012
cellular amino acid catabolic processGO:0009063310.012
regulation of atp metabolic processGO:1903578290.012
chemical homeostasisGO:00488783060.012
regulation of anatomical structure morphogenesisGO:00226032860.012
negative regulation of programmed cell deathGO:00430693210.011
ribonucleotide catabolic processGO:00092614050.011
response to external biotic stimulusGO:00432072610.011
single organism reproductive processGO:0044702980.011
2 oxoglutarate metabolic processGO:000610340.011
anatomical structure formation involved in morphogenesisGO:00486462840.011
Worm
alpha amino acid biosynthetic processGO:1901607230.011
gene silencing by rnaGO:0031047260.011
innate immune responseGO:00450871780.011
negative regulation of catalytic activityGO:00430863350.011
osteoblast differentiationGO:0001649920.011
response to woundingGO:00096111680.011
purine ribonucleotide catabolic processGO:00091544040.011
positive regulation of purine nucleotide metabolic processGO:19005442270.010
negative regulation of cellular catabolic processGO:0031330830.010
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.010
Fly
purine nucleoside triphosphate catabolic processGO:00091463920.010
protein targetingGO:00066051870.010
regulation of behaviorGO:0050795820.010
alpha amino acid metabolic processGO:1901605720.010

MDH2 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:00146672950.392
inherited metabolic disorderDOID:6552420.275
carbohydrate metabolic disorderDOID:2978550.092
amino acid metabolic disorderDOID:9252500.064
neurodegenerative diseaseDOID:12891020.048
nervous system diseaseDOID:8634310.048
central nervous system diseaseDOID:3311860.048
sensory system diseaseDOID:00501552030.032
eye and adnexa diseaseDOID:14921500.032
immune system diseaseDOID:29141550.017
hematopoietic system diseaseDOID:741000.017