Homo sapiens

93 known processes

HSP90B1

heat shock protein 90kDa beta (Grp94), member 1

(Aliases: GP96,GRP94,TRA1,ECGP)

HSP90B1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular response to topologically incorrect proteinGO:0035967190.994
endoplasmic reticulum unfolded protein responseGO:0030968160.991
response to unfolded proteinGO:0006986240.988
response to endoplasmic reticulum stressGO:0034976490.986
er nucleus signaling pathwayGO:0006984230.969
response to topologically incorrect proteinGO:0035966290.958
post embryonic developmentGO:000979120.913
Worm
cellular response to unfolded proteinGO:0034620160.899
intrinsic apoptotic signaling pathwayGO:00971931270.705
activation of signaling protein activity involved in unfolded protein responseGO:000698730.594
regenerationGO:003109940.535
endoplasmic reticulum organizationGO:0007029200.431
protein foldingGO:0006457380.420
apoptotic signaling pathwayGO:00971902680.418
negative regulation of neurological system processGO:003164520.340
determination of adult lifespanGO:000834020.279
positive regulation of developmental processGO:00510943140.260
chaperone mediated protein foldingGO:0061077130.253
regulation of intrinsic apoptotic signaling pathwayGO:2001242720.253
protein catabolic processGO:00301633250.216
ribonucleoside catabolic processGO:00424544060.201
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280690.193
nucleoside phosphate catabolic processGO:19012924120.186
purine nucleoside catabolic processGO:00061523980.150
modification dependent macromolecule catabolic processGO:00436322120.139
negative regulation of developmental processGO:00510932470.135
modification dependent protein catabolic processGO:00199412090.128
axon regenerationGO:003110310.127
posttranscriptional regulation of gene expressionGO:00106082130.119
regulation of cell cycle phase transitionGO:19019871260.119
proteolysis involved in cellular protein catabolic processGO:00516032440.119
ubiquitin dependent protein catabolic processGO:00065112060.114
activation of cysteine type endopeptidase activity involved in apoptotic processGO:0006919490.112
vesicle mediated transportGO:00161923710.108
Worm
multicellular organismal agingGO:001025930.101
protein localization to endoplasmic reticulumGO:0070972190.096
regulation of growthGO:00400081650.095
ribonucleotide catabolic processGO:00092614050.089
cellular response to cytokine stimulusGO:00713451810.088
negative regulation of programmed cell deathGO:00430693210.088
neuron projection regenerationGO:003110210.087
regulation of cell cycle processGO:00105642660.087
enzyme linked receptor protein signaling pathwayGO:00071673030.082
negative regulation of transforming growth factor beta receptor signaling pathwayGO:0030512280.081
regulation of cell motilityGO:20001452990.079
positive regulation of intrinsic apoptotic signaling pathwayGO:2001244280.079
purine ribonucleoside catabolic processGO:00461303980.079
purine ribonucleotide catabolic processGO:00091544040.078
cellular response to biotic stimulusGO:0071216710.077
positive regulation of catabolic processGO:00098963100.073
membrane organizationGO:00610242920.073
response to inorganic substanceGO:00100351270.071
regulation of proteolysisGO:00301622930.070
protein transmembrane transportGO:0071806250.069
oxidation reduction processGO:00551143960.069
endomembrane system organizationGO:00102561960.066
positive regulation of hydrolase activityGO:00513453310.066
eye pigmentationGO:004806910.063
regulation of homeostatic processGO:00328441210.063
lipid localizationGO:00108761060.063
Worm
hindbrain developmentGO:003090230.062
positive regulation of purine nucleotide catabolic processGO:00331231850.061
regulation of nuclease activityGO:0032069110.058
cell cycle phase transitionGO:00447701730.058
positive regulation of apoptotic signaling pathwayGO:2001235700.058
response to axon injuryGO:004867810.057
maintenance of protein localization in organelleGO:0072595150.057
intrinsic apoptotic signaling pathway in response to oxidative stressGO:0008631210.057
regulation of purine nucleotide catabolic processGO:00331212050.056
cellular macromolecule catabolic processGO:00442653800.055
negative regulation of phosphorus metabolic processGO:00105632670.054
receptor mediated endocytosisGO:0006898840.053
Worm
glycosyl compound catabolic processGO:19016584130.051
maintenance of protein locationGO:0045185570.051
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.050
establishment of protein localization to membraneGO:00901501210.049
regulation of bindingGO:00510981110.048
positive regulation of endopeptidase activityGO:0010950840.048
male genitalia developmentGO:003053910.048
response to transforming growth factor betaGO:0071559940.047
regulation of peptidase activityGO:00525471800.047
regulation of endopeptidase activityGO:00525481700.046
organophosphate catabolic processGO:00464344300.046
actin filament based processGO:00300292240.046
response to organic cyclic compoundGO:00140702040.044
regulation of cell migrationGO:00303342890.043
ribonucleoside monophosphate catabolic processGO:00091581580.043
regulation of behaviorGO:0050795820.043
response to cytokineGO:00340972320.043
neuronal action potentialGO:001922890.043
locomotory behaviorGO:000762610.042
regulation of cell cycleGO:00517263930.042
nucleotide catabolic processGO:00091664080.041
cellular response to lipidGO:00713961270.041
purine nucleotide catabolic processGO:00061954050.040
single organism cellular localizationGO:19025803320.040
growthGO:00400072020.040
reproductive processGO:00224141060.040
protein n linked glycosylationGO:0006487230.040
protein localization to organelleGO:00333652800.039
agingGO:0007568660.039
cellular response to endogenous stimulusGO:00714953360.039
zymogen activationGO:0031638700.038
fatty acid metabolic processGO:00066311150.038
protein targeting to membraneGO:0006612420.038
intracellular protein transportGO:00068862700.037
negative regulation of apoptotic processGO:00430663160.037
intracellular protein transmembrane transportGO:0065002240.037
regulation of cysteine type endopeptidase activityGO:20001161270.037
regulation of apoptotic signaling pathwayGO:20012331750.036
proteasomal protein catabolic processGO:00104981760.036
regulation of cell differentiationGO:00455953930.036
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.035
maintenance of locationGO:00512351120.035
Worm
response to abiotic stimulusGO:00096283360.034
protein stabilizationGO:0050821640.034
transmembrane transportGO:00550853990.034
regulation of locomotionGO:00400123290.034
system processGO:00030083490.034
ribonucleoside triphosphate catabolic processGO:00092033910.034
transforming growth factor beta receptor signaling pathwayGO:0007179760.033
monocarboxylic acid metabolic processGO:00327871850.033
somitogenesisGO:000175620.033
cytoplasmic transportGO:00164823790.032
response to oxygen containing compoundGO:19017003690.032
protein ubiquitinationGO:00165673140.032
rhythmic behaviorGO:000762220.032
cellular response to transforming growth factor beta stimulusGO:0071560940.032
mitotic cell cycle phase transitionGO:00447721620.031
mitotic cell cycleGO:00002783260.031
sex differentiationGO:0007548450.031
regulation of t cell activationGO:0050863770.030
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stressGO:0070059120.030
nervous system developmentGO:00073992930.030
purine ribonucleoside metabolic processGO:00461284370.029
negative regulation of catalytic activityGO:00430863350.029
cerebellar cortex developmentGO:002169510.029
positive regulation of growthGO:0045927580.028
response to biotic stimulusGO:00096072760.028
negative regulation of cellular protein metabolic processGO:00322693530.028
endocytosisGO:00068971590.028
Worm
negative regulation of cell deathGO:00605483450.028
activation of cysteine type endopeptidase activityGO:0097202570.028
positive regulation of multicellular organism growthGO:004001860.028
atp catabolic processGO:00062001570.027
negative regulation of multicellular organismal processGO:00512413170.027
response to disaccharideGO:003428510.027
regulation of mitotic cell cycleGO:00073461890.027
positive regulation of cellular catabolic processGO:00313312840.027
calcium mediated signalingGO:0019722440.027
response to growth factorGO:00708482050.026
positive regulation of cysteine type endopeptidase activityGO:2001056790.025
nucleoside monophosphate catabolic processGO:00091251590.025
cellular protein catabolic processGO:00442572610.025
purine nucleoside monophosphate catabolic processGO:00091281580.025
reproductionGO:0000003630.024
Worm
neurological system processGO:00508771630.024
negative regulation of protein phosphorylationGO:00019331400.024
regulation of atpase activityGO:0043462250.024
regulation of membrane potentialGO:0042391950.024
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090101450.023
positive regulation of developmental growthGO:0048639160.023
positive regulation of proteolysisGO:00458621420.023
nucleoside triphosphate catabolic processGO:00091433940.023
protein maturationGO:00516042330.022
embryo developmentGO:00097901230.022
Worm
regulation of atp metabolic processGO:1903578290.022
brain developmentGO:0007420970.022
positive regulation of extrinsic apoptotic signaling pathwayGO:2001238260.022
midbrain developmentGO:0030901450.021
protein localization to membraneGO:00726571600.021
regulation of cellular amino acid metabolic processGO:000652160.021
er associated ubiquitin dependent protein catabolic processGO:0030433310.021
positive regulation of programmed cell deathGO:00430682490.021
negative regulation of protein metabolic processGO:00512483910.021
positive regulation of nucleotide catabolic processGO:00308131850.021
autophagyGO:0006914880.021
positive regulation of protein modification by small protein conjugation or removalGO:1903322610.021
cellular amino acid metabolic processGO:00065201160.021
regulation of cellular protein catabolic processGO:1903362960.021
purine ribonucleoside triphosphate catabolic processGO:00092073910.020
positive regulation of cell differentiationGO:00455972110.020
synaptic vesicle endocytosisGO:004848820.020
nucleoside triphosphate metabolic processGO:00091414220.020
toxin transportGO:190199840.020
metencephalon developmentGO:002203720.020
regulation of translationGO:0006417890.020
positive regulation of immune system processGO:00026842830.019
purine containing compound catabolic processGO:00725234110.019
purine ribonucleoside triphosphate metabolic processGO:00092054110.019
heart developmentGO:0007507950.019
regulation of nucleoside metabolic processGO:00091182090.019
positive regulation of protein ubiquitinationGO:0031398530.019
mitotic cell cycle processGO:19030472860.019
intracellular receptor signaling pathwayGO:00305221040.019
male sex differentiationGO:0046661250.019
regulation of mitotic cell cycle phase transitionGO:19019901180.018
protein modification by small protein conjugationGO:00324463420.018
guanosine containing compound catabolic processGO:19010692390.018
regulation of meiotic cell cycleGO:005144540.018
oocyte differentiationGO:000999420.018
cellular response to growth factor stimulusGO:00713631970.017
calcium ion transport into cytosolGO:0060402480.017
regulation of cellular ketone metabolic processGO:0010565500.017
single organism reproductive processGO:0044702980.017
regulation of ion transportGO:00432691890.017
regulation of cellular response to stressGO:00801352440.017
cellular metal ion homeostasisGO:00068751460.017
cellular component morphogenesisGO:00329893140.017
regulation of wnt protein secretionGO:006135610.017
negative regulation of phosphate metabolic processGO:00459362670.017
regulation of cellular component movementGO:00512703340.017
response to nitrogen compoundGO:19016981840.017
regulation of response to external stimulusGO:00321012220.017
single organism membrane organizationGO:00448022680.017
response to lipidGO:00339932060.017
cellular protein complex assemblyGO:00436231880.016
negative regulation of cell cycleGO:00457861930.016
regulation of nucleotide metabolic processGO:00061402690.016
circulatory system developmentGO:00723592620.016
response to extracellular stimulusGO:0009991850.016
reproductive system developmentGO:0061458560.016
multicellular organismal reproductive processGO:0048609400.016
head developmentGO:00603221080.016
regulation of protein stabilityGO:0031647870.016
purine nucleoside triphosphate metabolic processGO:00091444120.016
negative regulation of cell cycle processGO:00109481210.016
protein oligomerizationGO:00512591730.015
positive regulation of cytosolic calcium ion concentrationGO:0007204820.015
ribonucleoside triphosphate metabolic processGO:00091994120.015
regulation of metal ion transportGO:00109591200.015
cardiovascular system developmentGO:00723582620.015
response to fungusGO:000962040.015
oogenesisGO:004847720.015
regulation of i kappab kinase nf kappab signalingGO:00431221620.015
reactive oxygen species metabolic processGO:0072593750.015
translationGO:00064121320.015
response to metal ionGO:0010038840.015
anterior posterior axis specificationGO:000994820.015
positive regulation of cell deathGO:00109422630.015
cellular divalent inorganic cation homeostasisGO:00725031280.015
regulation of protein ubiquitinationGO:0031396950.014
fat cell differentiationGO:0045444320.014
positive regulation of nucleotide metabolic processGO:00459812300.014
regulation of autophagyGO:0010506520.014
activation of phospholipase d activityGO:003158430.014
positive regulation of peptidase activityGO:0010952880.014
purine nucleoside triphosphate catabolic processGO:00091463920.014
positive regulation of i kappab kinase nf kappab signalingGO:00431231320.014
cellular response to dna damage stimulusGO:00069743790.014
cellular response to lithium ionGO:007128520.014
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092900.014
divalent inorganic cation transportGO:00725111580.014
central nervous system developmentGO:00074171230.013
response to sucroseGO:000974410.013
positive regulation of cellular component movementGO:00512721810.013
protein processingGO:00164852260.013
developmental growthGO:0048589480.013
circadian behaviorGO:004851220.013
nuclear exportGO:0051168690.013
microtubule based processGO:00070172100.013
positive regulation of systemic arterial blood pressureGO:000308420.013
regulation of transforming growth factor beta receptor signaling pathwayGO:0017015480.013
cellular amine metabolic processGO:0044106410.013
reproductive structure developmentGO:0048608550.012
response to electrical stimulusGO:005160210.012
embryo development ending in birth or egg hatchingGO:0009792340.012
Worm
cellular homeostasisGO:00197251960.012
oocyte developmentGO:004859910.012
positive regulation of cell developmentGO:0010720920.012
positive regulation of phosphorylationGO:00423273940.012
regulation of protein modification by small protein conjugation or removalGO:19033201070.012
negative regulation of cellular response to growth factor stimulusGO:0090288410.012
lipid catabolic processGO:0016042840.012
mitotic cell cycle checkpointGO:0007093680.012
protein targetingGO:00066051870.012
mitochondrion organizationGO:00070051560.012
response to peptideGO:1901652650.012
response to toxic substanceGO:0009636370.012
sleepGO:003043120.012
cellular chemical homeostasisGO:00550821800.012
sensory organ developmentGO:0007423520.012
Zebrafish
response to starvationGO:0042594590.012
divalent metal ion transportGO:00708381520.011
cation homeostasisGO:00550801890.011
cellular response to external stimulusGO:00714961110.011
renal system developmentGO:0072001630.011
lymphocyte activationGO:00466491330.011
primary neural tube formationGO:001402030.011
positive regulation of protein catabolic processGO:0045732750.011
regulation of neurogenesisGO:0050767820.011
cation transportGO:00068123310.011
positive regulation of nucleoside metabolic processGO:00459791860.011
establishment of protein localization to endoplasmic reticulumGO:0072599110.011
nucleocytoplasmic transportGO:00069131760.011
regulation of cell growthGO:00015581350.011
matingGO:000761810.011
regulation of dna replicationGO:0006275680.011
cellular response to insulin stimulusGO:0032869410.011
regulation of anatomical structure morphogenesisGO:00226032860.011
posttranscriptional gene silencingGO:0016441250.011
myosin filament organizationGO:003103320.011
glycogen metabolic processGO:0005977220.011
purine ribonucleoside monophosphate metabolic processGO:00091671860.011
cell growthGO:00160491600.011
cell divisionGO:00513011680.011
reactive nitrogen species metabolic processGO:200105730.011
t cell activationGO:0042110990.011
response to external biotic stimulusGO:00432072610.011
circadian sleep wake cycle sleepGO:005080220.011
response to estrogenGO:0043627470.011
gamete generationGO:0007276250.010
positive regulation of transferase activityGO:00513472270.010
cell cycle checkpointGO:00000751170.010
developmental process involved in reproductionGO:0003006660.010
rna interferenceGO:001624640.010
response to hormoneGO:00097251750.010
defense responseGO:00069523150.010
calcium ion transportGO:00068161470.010
neural nucleus developmentGO:0048857470.010
compound eye developmentGO:004874910.010
regulation of calcium ion transportGO:0051924790.010
regulation of cell morphogenesisGO:00226041530.010
cytosolic calcium ion transportGO:0060401480.010
leukocyte activationGO:00453211640.010

HSP90B1 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
bone development diseaseDOID:0080006550.052
bone diseaseDOID:0080001880.052
musculoskeletal system diseaseDOID:172230.052
connective tissue diseaseDOID:651090.052
organ system cancerDOID:00506861640.046
cancerDOID:1621670.046
disease of cellular proliferationDOID:145661740.046
anemiaDOID:2355550.026
immune system diseaseDOID:29141550.026
hematopoietic system diseaseDOID:741000.026
osteochondrodysplasiaDOID:2256350.022
nervous system diseaseDOID:8634310.011
central nervous system diseaseDOID:3311860.011
brain diseaseDOID:936730.011